328 Matching Annotations
  1. Oct 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MerTK+ macrophages promote melanoma progression and immunotherapy resistance through AhR-ALKAL1 activation
    1
    1. scibot 08 Oct 2024
      RRID:AB_1107769

      DOI: 10.1126/sciadv.ado8366

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    ncbi.nlm.nih.gov/pmc/articles/PMC11451552/
  3. www.biorxiv.org www.biorxiv.org
    Hematopoietic Tet2 inactivation enhances the response to checkpoint blockade immunotherapy
    1
    1. scibot 02 Oct 2024
      RRID:AB_1107769

      DOI: 10.1101/2024.09.09.612140

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    biorxiv.org/content/10.1101/2024.09.09.612140v1
  4. aacrjournals.org aacrjournals.org
    Targeting of CD40 and PD-L1 pathways inhibit progression of oral premalignant lesions in a carcinogen-induced model of oral squamous cell carcinoma
    1
    1. scibot 02 Oct 2024
      RRID:AB_1107769

      DOI: 10.1158/1940-6207.CAPR-20-0418

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    aacrjournals.org/cancerpreventionresearch/article/14/3/313/47829/Targeting-of-CD40-and-PD-L1-Pathways-Inhibits
  5. www.biorxiv.org www.biorxiv.org
    Trem2 deficiency attenuates breast cancer tumor growth in lean, but not obese or weight loss, mice and is associated with alterations of clonal T cell populations
    1
    1. scibot 02 Oct 2024
      RRID:AB_1107769

      DOI: 10.1101/2024.09.25.614811

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    biorxiv.org/content/10.1101/2024.09.25.614811v1
  6. Sep 2024
  7. www.sciencedirect.com www.sciencedirect.com
    Fusobacterium nucleatum facilitates anti-PD-1 therapy in microsatellite stable colorectal cancer
    1
    1. scibot 25 Sep 2024
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      DOI: 10.1016/j.ccell.2024.08.019

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    sciencedirect.com/science/article/pii/S1535610824003180
  8. www.sciencedirect.com www.sciencedirect.com
    Dietary vitamin B3 supplementation induces the antitumor immunity against liver cancer via biased GPR109A signaling in myeloid cell
    1
    1. scibot 25 Sep 2024
      AB_1107769

      DOI: 10.1016/j.xcrm.2024.101718

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    sciencedirect.com/science/article/pii/S2666379124004397
  9. www.sciencedirect.com www.sciencedirect.com
    Endothelial metabolic control of insulin sensitivity through resident macrophages
    1
    1. scibot 13 Sep 2024
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      DOI: 10.1016/j.cmet.2024.08.008

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    sciencedirect.com/science/article/pii/S1550413124003358
  10. www.sciencedirect.com www.sciencedirect.com
    Glioblastoma induces the recruitment and differentiation of dendritic-like “hybrid” neutrophils from skull bone marrow
    1
    1. scibot 10 Sep 2024
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      DOI: 10.1016/j.ccell.2024.08.008

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    sciencedirect.com/science/article/pii/S1535610824003076
  11. Aug 2024
  12. www.sciencedirect.com www.sciencedirect.com
    Secreted PTEN binds PLXDC2 on macrophages to drive antitumor immunity and tumor suppression
    1
    1. scibot 28 Aug 2024
      AB_1107769

      DOI: 10.1016/j.devcel.2024.08.003

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    sciencedirect.com/science/article/pii/S1534580724004866
  13. www.sciencedirect.com www.sciencedirect.com
    TNFR1 signaling promotes pancreatic tumor growth by limiting dendritic cell number and function
    1
    1. scibot 23 Aug 2024
      AB_1107769

      DOI: 10.1016/j.xcrm.2024.101696

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    sciencedirect.com/science/article/pii/S2666379124004178
  14. www.nature.com www.nature.com
    LIFR regulates cholesterol-driven bidirectional hepatocyte–neutrophil cross-talk to promote liver regeneration
    1
    1. scibot 23 Aug 2024
      RRID:AB_1107769

      DOI: 10.1038/s42255-024-01110-y

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    nature.com/articles/s42255-024-01110-y
  15. www.sciencedirect.com www.sciencedirect.com
    Airway extracellular LTA4H concentrations are governed by release from liver hepatocytes and changes in lung vascular permeability
    1
    1. scibot 21 Aug 2024
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      DOI: 10.1016/j.celrep.2024.114630

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    sciencedirect.com/science/article/pii/S221112472400980X
  16. www.sciencedirect.com www.sciencedirect.com
    Transcription factor Ikzf1 associates with Foxp3 to repress gene expression in Treg cells and limit autoimmunity and anti-tumor immunity
    1
    1. scibot 19 Aug 2024
      AB_1107769

      DOI: 10.1016/j.immuni.2024.07.010

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    sciencedirect.com/science/article/pii/S1074761324003595
  17. Jul 2024
  18. www.cell.com www.cell.com
    Fecal microbiota transplantation improves anti-PD-1 inhibitor efficacy in unresectable or metastatic solid cancers refractory to anti-PD-1 inhibitor
    1
    1. scibot 30 Jul 2024
      RRID:AB_1107769

      DOI: 10.1016/j.chom.2024.06.010

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    cell.com/cell-host-microbe/abstract/S1931-3128(24)00228-2
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    VHL loss enhances antitumor immunity by activating the anti-viral DNA-sensing pathway
    1
    1. scibot 27 Jul 2024
      RRID:AB_1107769

      DOI: 10.1016/j.isci.2024.110285

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    ncbi.nlm.nih.gov/pmc/articles/PMC11267025/
  20. www.sciencedirect.com www.sciencedirect.com
    Lymphatic-localized Treg-mregDC crosstalk limits antigen trafficking and restrains anti-tumor immunity
    1
    1. scibot 25 Jul 2024
      AB_1107769

      DOI: 10.1016/j.ccell.2024.06.014

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    sciencedirect.com/science/article/pii/S1535610824002393
  21. www.science.org www.science.org
    Type I conventional dendritic cells facilitate immunotherapy in pancreatic cancer
    1
    1. scibot 25 Jul 2024
      RRID:AB_1107769

      DOI: 10.1126/science.adh4567

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    science.org/doi/10.1126/science.adh4567
  22. www.cell.com www.cell.com
    Macrophages preserve endothelial cell specialization in the adrenal gland to modulate aldosterone secretion and blood pressure
    1
    1. scibot 19 Jul 2024
      RRID:AB_1107769

      DOI: 10.1016/j.celrep.2024.114395

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    cell.com/cell-reports/fulltext/S2211-1247(24)00723-X
  23. www.biorxiv.org www.biorxiv.org
    Immune Checkpoint Inhibition-related Neuroinflammation Disrupts Cognitive Function
    1
    1. scibot 16 Jul 2024
      RRID:AB_1107769

      DOI: 10.1101/2024.07.01.601087

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    biorxiv.org/content/10.1101/2024.07.01.601087v1
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: Second-generation checkpoint inhibitors and Treg depletion synergize with a mouse cancer vaccine in accordance with tumor microenvironment characterization
    1
    1. scibot 04 Jul 2024
      RRID:AB_1107769

      DOI: 10.1136/jitc-2024-008970

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    ncbi.nlm.nih.gov/pmc/articles/PMC11218019/
  25. Jun 2024
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    p53 gain-of-function mutation induces metastasis via Brd4-dependent Csf-1 expression
    1
    1. scibot 13 Jun 2024
      RRID:AB_1107769

      DOI: 10.1158/2159-8290.CD-23-0601

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    ncbi.nlm.nih.gov/pmc/articles/PMC10841313/
  27. www.sciencedirect.com www.sciencedirect.com
    Clonal hematopoiesis driven by mutated DNMT3A promotes inflammatory bone loss
    1
    1. scibot 05 Jun 2024
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      DOI: 10.1016/j.cell.2024.05.003

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    sciencedirect.com/science/article/pii/S0092867424004926
  28. www.sciencedirect.com www.sciencedirect.com
    Blockage of L2HGDH-mediated S-2HG catabolism orchestrates macrophage polarization to elicit antitumor immunity
    1
    1. scibot 04 Jun 2024
      RRID:AB_1107769

      DOI: 10.1016/j.celrep.2024.114300

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    sciencedirect.com/science/article/pii/S2211124724006284
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Opposing tumor-cell-intrinsic and -extrinsic roles of the IRF1 transcription factor in antitumor immunity
    1
    1. scibot 04 Jun 2024
      RRID:AB_1107769

      DOI: 10.1016/j.celrep.2024.114289

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    ncbi.nlm.nih.gov/pmc/articles/PMC11315447/
  30. May 2024
  31. www.sciencedirect.com www.sciencedirect.com
    A computational pipeline for identifying gene targets and signalling pathways in cancer cells to improve lymphocyte infiltration and immune checkpoint therapy efficacy
    1
    1. scibot 30 May 2024
      RRID:AB_1107769

      DOI: 10.1016/j.ebiom.2024.105167

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    sciencedirect.com/science/article/pii/S2352396424002020
  32. www.sciencedirect.com www.sciencedirect.com
    Clostridioides difficile toxin B subverts germinal center and antibody recall responses by stimulating a drug-treatable CXCR4-dependent mechanism
    1
    1. scibot 21 May 2024
      RRID:AB_1107769

      DOI: 10.1016/j.celrep.2024.114245

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    sciencedirect.com/science/article/pii/S2211124724005734
  33. www.sciencedirect.com www.sciencedirect.com
    Metabolic regulator LKB1 controls adipose tissue ILC2 PD-1 expression and mitochondrial homeostasis to prevent insulin resistance
    1
    1. scibot 21 May 2024
      RRID:AB_1107769

      DOI: 10.1016/j.immuni.2024.04.024

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    sciencedirect.com/science/article/pii/S1074761324002292
  34. www.sciencedirect.com www.sciencedirect.com
    One-carbon unit supplementation fuels purine synthesis in tumor-infiltrating T cells and augments checkpoint blockade
    1
    1. scibot 17 May 2024
      RRID:AB_1107769

      DOI: 10.1016/j.chembiol.2024.04.007

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    sciencedirect.com/science/article/pii/S2451945624001697
  35. www.sciencedirect.com www.sciencedirect.com
    Circadian tumor infiltration and function of CD8+ T cells dictate immunotherapy efficacy
    1
    1. scibot 09 May 2024
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      DOI: 10.1016/j.cell.2024.04.015

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    sciencedirect.com/science/article/pii/S0092867424004100
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chalkophore mediated respiratory oxidase flexibility controls M. tuberculosis virulence
    1
    1. scibot 01 May 2024
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      DOI: 10.1101/2024.04.12.589290

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    ncbi.nlm.nih.gov/pmc/articles/PMC11030325/
  37. Apr 2024
  38. www.sciencedirect.com www.sciencedirect.com
    Exogenous non-coding dsDNA-dependent trans-activation of phagocytes augments anti-tumor immunity
    1
    1. scibot 30 Apr 2024
      BioXcellBP0089

      DOI: 10.1016/j.xcrm.2024.101528

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    sciencedirect.com/science/article/pii/S2666379124001976
  39. www.sciencedirect.com www.sciencedirect.com
    LKB1 prevents ILC2 exhaustion to enhance antitumor immunity
    1
    1. scibot 26 Apr 2024
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      DOI: 10.1016/j.celrep.2023.113579

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    sciencedirect.com/science/article/pii/S2211124723015917
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    Batf3+ DCs and the 4-1BB/4-1BBL axis are required at the effector phase in the tumor microenvironment for PD-1/PD-L1 blockade efficacy
    1
    1. scibot 24 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114141

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    sciencedirect.com/science/article/pii/S2211124724004698
  41. www.sciencedirect.com www.sciencedirect.com
    QDPR deficiency drives immune suppression in pancreatic cancer
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    1. scibot 23 Apr 2024
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      DOI: 10.1016/j.cmet.2024.03.015

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    sciencedirect.com/science/article/pii/S1550413124001190
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TL1A is an epithelial alarmin that cooperates with IL-33 for initiation of allergic airway inflammation
    1
    1. scibot 18 Apr 2024
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      DOI: 10.1084/jem.20231236

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    ncbi.nlm.nih.gov/pmc/articles/PMC11010340/
  43. www.sciencedirect.com www.sciencedirect.com
    Intraepithelial mast cells drive gasdermin C-mediated type 2 immunity
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      DOI: 10.1016/j.immuni.2024.03.017

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      DOI: 10.1016/j.immuni.2024.03.017

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    sciencedirect.com/science/article/pii/S1074761324001389
  44. www.sciencedirect.com www.sciencedirect.com
    CXCL9/10-engineered dendritic cells promote T cell activation and enhance immune checkpoint blockade for lung cancer
    1
    1. scibot 12 Apr 2024
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      DOI: 10.1016/j.xcrm.2024.101479

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    sciencedirect.com/science/article/pii/S2666379124001253
  45. www.sciencedirect.com www.sciencedirect.com
    Genetic interactions reveal distinct biological and therapeutic implications in breast cancer
    1
    1. scibot 09 Apr 2024
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      DOI: 10.1016/j.ccell.2024.03.006

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    sciencedirect.com/science/article/pii/S1535610824000916
  46. Mar 2024
  47. www.sciencedirect.com www.sciencedirect.com
    Hippo-signaling-controlled MHC class I antigen processing and presentation pathway potentiates antitumor immunity
    1
    1. scibot 27 Mar 2024
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      DOI: 10.1016/j.celrep.2024.114003

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    sciencedirect.com/science/article/pii/S2211124724003310
  48. www.sciencedirect.com www.sciencedirect.com
    Biofilm exopolysaccharides alter sensory-neuron-mediated sickness during lung infection
    1
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    Neutrophil-inflicted vasculature damage suppresses immune-mediated optic nerve regeneration
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    Microbial metabolite enhances immunotherapy efficacy by modulating T cell stemness in pan-cancer
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    Long-lasting mRNA-encoded interleukin-2 restores CD8+ T cell neoantigen immunity in MHC class I-deficient cancers
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    Wnt5 controls splenic myelopoiesis and neutrophil functional ambivalency during DSS-induced colitis
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  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    S100A9+CD14+ monocytes contribute to anti-PD-1 immunotherapy resistance in advanced hepatocellular carcinoma by attenuating T cell-mediated antitumor function
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    Leishmania braziliensis enhances monocyte responses to promote anti-tumor activity
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  56. Feb 2024
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    UFL1 ablation in T cells suppresses PD-1 UFMylation to enhance anti-tumor immunity
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    The CD27/CD70 pathway negatively regulates visceral adipose tissue-resident Th2 cells and controls metabolic homeostasis
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    Suppression of adaptive NK cell expansion by macrophage-mediated phagocytosis inhibited by 2B4-CD48
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    Disruption of MerTK increases the efficacy of checkpoint inhibitor by enhancing ferroptosis and immune response in hepatocellular carcinoma
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    EZH2 Inhibition Promotes Tumor Immunogenicity in Lung Squamous Cell Carcinomas
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    Loss of TIM4-Dependent Efferocytosis in Kupffer Cells Promotes Liver Fibrosis in Nonalcoholic Steatohepatitis
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    Inflammatory dendritic cells restrain CD11b+CD4+ CTLs via CD200R in human NSCLC
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    Extracellular-vesicle-packaged S100A11 from osteosarcoma cells mediates lung premetastatic niche formation by recruiting gMDSCs
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    An axon-T cell feedback loop enhances inflammation and axon degeneration
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    Tumor-secreted FGF21 acts as an immune suppressor by rewiring cholesterol metabolism of CD8+T cells
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    Interrogation of endothelial and mural cells in brain metastasis reveals key immune-regulatory mechanisms
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    DNA damage repair profiling of esophageal squamous cell carcinoma uncovers clinically relevant molecular subtypes with distinct prognoses and therapeutic vulnerabilities
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    Skin microbe-dependent TSLP-ILC2 priming axis in early life is co-opted in allergic inflammation
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    Formate supplementation enhances anti-tumor CD8+ T cell fitness and efficacy of PD-1 blockade
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  73. 52.53.155.43 52.53.155.43
    Mitochondria-ER contact mediated by MFN2-SERCA2 interaction supports CD8+ T cell metabolic fitness and function in tumors
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    Interferon-stimulated neutrophils as a predictor of immunotherapy response
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    Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T cells
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  76. Dec 2023
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preventive Treatment with PD-1 Antibody Increases Tissue-Resident Memory T Cells Infiltration and Delays Esophageal Carcinogenesis
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    The tumor-derived cytokine Chi3l1 induces neutrophil extracellular traps that promote T cell exclusion in triple-negative breast cancer
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    IL-18-induced HIF-1α in ILC3s ameliorates the inflammation of C. rodentium-induced colitis
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  82. 52.53.155.43 52.53.155.43
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  83. Nov 2023
  84. www.cell.com www.cell.com
    Prolonged sleep deprivation induces a cytokine-storm-like syndrome in mammals
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    E3 ligase Trim35 inhibits LSD1 demethylase activity through K63-linked ubiquitination and enhances anti-tumor immunity in NSCLC
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    CD115+ monocytes protect microbially experienced mice against E. coli-induced sepsis
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  87. Oct 2023
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    Kruppel-like factor 2+ CD4 T cells avert microbiota-induced intestinal inflammation
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  89. www.sciencedirect.com www.sciencedirect.com
    Targeting VCP potentiates immune checkpoint therapy for colorectal cancer
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  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MEK inhibitors increase the mortality rate in mice with LPS-induced inflammation through IL-12-NO signaling
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  91. www.sciencedirect.com www.sciencedirect.com
    Progenitor-like exhausted SPRY1+CD8+ T cells potentiate responsiveness to neoadjuvant PD-1 blockade in esophageal squamous cell carcinoma
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    TIM-3 blockade in diffuse intrinsic pontine glioma models promotes tumor regression and antitumor immune memory
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    Supplementation with a high-glucose drink stimulates anti-tumor immune responses to glioblastoma via gut microbiota modulation
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    The CX3CL1-CX3CR1 chemokine axis can contribute to tumor immune evasion and blockade with a novel CX3CR1 monoclonal antibody enhances response to anti-PD-1 immunotherapy
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    Endothelial cells are a key target of IFN-g during response to combined PD-1/CTLA-4 ICB treatment in a mouse model of bladder cancer
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    Neutrophil extracellular traps enhance S. aureus skin colonization by oxidative stress induction and downregulation of epidermal barrier genes
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  97. Sep 2023
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    Regulatory T cells require IL6 receptor alpha signaling to control skeletal muscle function and regeneration
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    Ablation of ERO1A induces lethal endoplasmic reticulum stress responses and immunogenic cell death to activate anti-tumor immunity
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    Sex-Biased T-cell Exhaustion Drives Differential Immune Responses in Glioblastoma
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  101. Aug 2023
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    Sepsis induces non-classic innate immune memory in granulocytes
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    Activating Inducible T cell Co-stimulator (ICOS) yields anti-tumor activity alone and in combination with anti-PD-1 checkpoint blockade
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    CRISPR-Cas9 screening identifies an IRF1-SOCS1-mediated negative feedback loop that limits CXCL9 expression and antitumor immunity
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  105. 52.53.155.43 52.53.155.43
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  106. 52.53.155.43 52.53.155.43
    CD39 inhibition and VISTA blockade may overcome radiotherapy resistance by targeting exhausted CD8+ T cells and immunosuppressive myeloid cells
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    A CSF-1R-blocking antibody/IL-10 fusion protein increases anti-tumor immunity by effectuating tumor-resident CD8+ T cells
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    METTL3 drives NAFLD-related hepatocellular carcinoma and is a therapeutic target for boosting immunotherapy
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    TIM3 is a context-dependent co-regulator of cytotoxic T cell function
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  110. 52.53.155.43 52.53.155.43
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  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    OncoLoop: A network-based precision cancer medicine framework
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  112. Jul 2023
  113. www.sciencedirect.com www.sciencedirect.com
    SMYD3 represses tumor-intrinsic interferon response in HPV-negative squamous cell carcinoma of the head and neck
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    Lung injury induces a polarized immune response by self-antigen-specific CD4+ Foxp3+ regulatory T cells
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    Macrophage-mediated extracellular matrix remodeling controls host Staphylococcus aureus susceptibility in the skin
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    TCR-independent CD137 (4-1BB) signaling promotes CD8+-exhausted T cell proliferation and terminal differentiation
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  117. Jun 2023
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    Tumor-derived prostaglandin E2 programs cDC1 dysfunction to impair intratumoral orchestration of anti-cancer T cell responses
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    PD-L1/PD-1 checkpoint pathway regulates hippocampal neuronal excitability and learning and memory behavior
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    Cholesterol efflux pathways hinder KRAS-driven lung tumor progenitor cell expansion
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    Methionine restriction promotes cGAS activation and chromatin untethering through demethylation to enhance antitumor immunity
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    Clearance of senescent macrophages ameliorates tumorigenesis in KRAS-driven lung cancer
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  123. May 2023
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    IL-1β-associated NNT acetylation orchestrates iron-sulfur cluster maintenance and cancer immunotherapy resistance
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    CCL19+ dendritic cells potentiate clinical benefit of anti-PD-(L)1 immunotherapy in triple-negative breast cancer
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    Tailoring vascular phenotype through AAV therapy promotes anti-tumor immunity in glioma
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  127. www.biorxiv.org www.biorxiv.org
    LIFR recruits HGF-producing neutrophils to promote liver injury repair and regeneration
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    Fusobacterium nucleatum-derived succinic acid induces tumor resistance to immunotherapy in colorectal cancer
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  129. Apr 2023
  130. aacrjournals.org aacrjournals.org
    Targeting ULK1 decreases interferon-γ-mediated resistance to immune checkpoint inhibitors
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    Lenvatinib or anti-VEGF in combination with anti-PD-1 differentially augments anti-tumor activity in melanoma
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    Neutrophil Conversion to a Tumor-Killing Phenotype Underpins Effective Microbial Therapy
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    Identification of fibrocyte cluster in tumors reveals the role in antitumor immunity by PD-L1 blockade
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    NK cell-derived extracellular granzyme B drives epithelial ulceration during HSV-2 genital infection
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    Variant enterovirus A71 found in immune-suppressed patient binds to heparan sulfate and exhibits neurotropism in B-cell-depleted mice
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    Age-dependent differences in efferocytosis determine the outcome of opsonophagocytic protection from invasive pathogens
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    Lymphocyte networks are dynamic cellular communities in the immunoregulatory landscape of lung adenocarcinoma
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    An optimized IL-12-Fc expands its therapeutic window, achieving strong activity against mouse tumors at tolerable drug doses
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    Liposome-Encapsulated Eribulin Shows Enhanced Antitumor Activity over Eribulin for Combination Therapy with Anti–PD-1 Antibody
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  140. www.nature.com www.nature.com
    Targeting USP2 regulation of VPRBP-mediated degradation of p53 and PD-L1 for cancer therapy
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  141. www.sciencedirect.com www.sciencedirect.com
    Lacticaseibacillus rhamnosus Probio-M9 enhanced the antitumor response to anti-PD-1 therapy by modulating intestinal metabolites
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  142. Mar 2023
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    Thymus Antibody-Secreting Cells Possess an Interferon Gene Signature and are Preferentially Expanded in Young Female Mice
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  144. Feb 2023
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    Intratumoral CD8+ T cells with a tissue-resident memory phenotype mediate local immunity and immune checkpoint responses in breast cancer
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  146. Jan 2023
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    Neutrophil-activating therapy for the treatment of cancer
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    S-adenosylmethionine blocks tumorigenesis and with immune checkpoint inhibitor enhances anti-cancer efficacy against BRAF mutant and wildtype melanomas
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    MHC class II-restricted antigen presentation is required to prevent dysfunction of cytotoxic T cells by blood-borne myeloids in brain tumors
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    Vitamin E Enhances Cancer Immunotherapy by Reinvigorating Dendritic Cells via Targeting Checkpoint SHP1
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    Microglia drive transient insult-induced brain injury by chemotactic recruitment of CD8+ T lymphocytes
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  152. Dec 2022
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    Alveolar macrophages instruct CD8+ T cell expansion by antigen cross-presentation in lung
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    IL-5-producing CD4+ T cells and eosinophils cooperate to enhance response to immune checkpoint blockade in breast cancer
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    Cancer cell-derived type I interferons instruct tumor monocyte polarization
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    Mouse placenta fetal macrophages arise from endothelial cells outside the placenta
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  158. Nov 2022
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    STAT3 gain-of-function mutations connect leukemia with autoimmune disease by pathological NKG2Dhi CD8+ T cell dysregulation and accumulation
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    Driving axon regeneration by orchestrating neuronal and non-neuronal innate immune responses via the IFNγ-cGAS-STING axis
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    Cardiac myosin-specific autoimmune T cells contribute to immune-checkpoint-inhibitor-associated myocarditis
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    Mobilizing phospholipids on tumor plasma membrane implicates phosphatidylserine externalization blockade for cancer immunotherapy
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  163. Oct 2022
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    Ferroptosis heterogeneity in triple-negative breast cancer reveals an innovative immunotherapy combination strategy
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    Gut microbiome dysbiosis contributes to abdominal aortic aneurysm by promoting neutrophil extracellular trap formation
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    PARP-inhibition reprograms macrophages toward an anti-tumor phenotype
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  167. Sep 2022
  168. www.sciencedirect.com www.sciencedirect.com
    Tumor-associated macrophages are shaped by intratumoral high potassium via Kir2.1
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    Balance between immunoregulatory B cells and plasma cells drives pancreatic tumor immunity
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    Intestinal Inflammation Reversibly Alters the Microbiota to Drive Susceptibility to Clostridioides difficile Colonization in a Mouse Model of Colitis
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  171. Aug 2022
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    B Cells Produce the Tissue-Protective Protein RELMα during Helminth Infection, which Inhibits IL-17 Expression and Limits Emphysema
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    Aerobic glycolysis promotes tumor immune evasion by hexokinase2-mediated phosphorylation of IκBα
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    Stromal remodeling regulates dendritic cell abundance and activity in the tumor microenvironment
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    Blocking DCIR mitigates colitis and prevents colorectal tumors by enhancing the GM-CSF-STAT5 pathway
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    Lung fibroblasts facilitate pre-metastatic niche formation by remodeling the local immune microenvironment
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  177. Jul 2022
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    Keratinocyte-derived defensins activate neutrophil-specific receptors Mrgpra2a/b to prevent skin dysbiosis and bacterial infection
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    Tumor cells dictate anti-tumor immune responses by altering pyruvate utilization and succinate signaling in CD8+ T cells
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  180. Jun 2022
  181. 52.53.155.43 52.53.155.43
    cd-21-1022-html.html
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      DOI: 10.1158/2159-8290.CD-21-1022

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  182. 52.53.155.43 52.53.155.43
    cd-21-0900-html.html
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  183. www.sciencedirect.com www.sciencedirect.com
    Androgens drive sexual dimorphism in liver metastasis by promoting hepatic accumulation of neutrophils
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  184. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Senescence-induced endothelial phenotypes underpin immune-mediated senescence surveillance
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  185. www.sciencedirect.com www.sciencedirect.com
    Unravelling the sex-specific diversity and functions of adrenal gland macrophages
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    Poroptosis: a form of cell death depending on plasma membrane nanopores formation
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    Nt5e deficiency does not affect post-stroke inflammation and lesion size in a murine ischemia/reperfusion stroke model
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    Flow cytometry analysis of endothelial cells and subsets of exhausted CD8+ T cells in murine tumor models
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    PGE2-EP2/EP4 signaling elicits immunosuppression by driving the mregDC-Treg axis in inflammatory tumor microenvironment
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  190. May 2022
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    Newly recruited intraepithelial Ly6A+CCR9+CD4+ T cells protect against enteric viral infection
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    The C5a-C5aR1 complement axis is essential for neutrophil recruitment to draining lymph nodes via high endothelial venules in cutaneous leishmaniasis
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    Mesothelial cell-derived antigen-presenting cancer-associated fibroblasts induce expansion of regulatory T cells in pancreatic cancer
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    Colony stimulating factor-1 producing endothelial cells and mesenchymal stromal cells maintain monocytes within a perivascular bone marrow niche
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  195. Apr 2022
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    Treg tissue stability depends on lymphotoxin beta-receptor- and adenosine-receptor-driven lymphatic endothelial cell responses
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    The interferon-stimulated gene RIPK1 regulates cancer cell intrinsic and extrinsic resistance to immune checkpoint blockade
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    Differential regulation of transcription factor T-bet induction during NK cell development and T helper-1 cell differentiation
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  199. aacrjournals.org aacrjournals.org
    mDKN-01, a Novel Anti-DKK1 mAb, Enhances Innate Immune Responses in the Tumor Microenvironment
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      DOI: 10.1158/1541-7786.MCR-20-0799

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  200. Mar 2022
  201. www.sciencedirect.com www.sciencedirect.com
    Secondary influenza challenge triggers resident memory B cell migration and rapid relocation to boost antibody secretion at infected sites
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    The microbial metabolite trimethylamine N-oxide promotes antitumor immunity in triple-negative breast cancer
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  203. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Heterogeneity of tyrosine-based melanin anabolism regulates pulmonary and cerebral organotropic colonization microenvironment of melanoma cells
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      DOI: 10.7150/thno.69198

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  204. elifesciences.org elifesciences.org
    A non-bactericidal cathelicidin provides prophylactic efficacy against bacterial infection by driving phagocyte influx
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    CD8+ T cells and fatty acids orchestrate tumor ferroptosis and immunity via ACSL4
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  206. Feb 2022
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    An adjuvant strategy enabled by modulation of the physical properties of microbial ligands expands antigen immunogenicity
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    Tumor-associated high endothelial venules mediate lymphocyte entry into tumors and predict response to PD-1 plus CTLA-4 combination immunotherapy
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  209. www.jneurosci.org www.jneurosci.org
    Embryonic pericytes promote microglial homeostasis and their effects on neural progenitors in the developing cerebral cortex
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  210. Jan 2022
  211. www.sciencedirect.com www.sciencedirect.com
    Magnesium sensing via LFA-1 regulates CD8+ T cell effector function
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    MEK inhibition overcomes chemoimmunotherapy resistance by inducing CXCL10 in cancer cells
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    Adenosine 2A receptor and TIM3 suppress cytolytic killing of tumor cells via cytoskeletal polarization
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  214. www.sciencedirect.com www.sciencedirect.com
    Helminth resistance is mediated by differential activation of recruited monocyte-derived alveolar macrophages and arginine depletion
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  215. Dec 2021
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    Virulence factors perforate the pathogen-containing vacuole to signal efferocytosis
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    Resolving the immune landscape of human prostate at a single-cell level in health and cancer
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