215 Matching Annotations
  1. Dec 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Inhibiting intracellular CD28 in cancer cells enhances antitumor immunity and overcomes anti-PD-1 resistance via targeting PD-L1
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    1. scibot 14 Dec 2024
      RRID:AB_1107780

      DOI: 10.1016/j.ccell.2024.11.008

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    sciencedirect.com/science/article/pii/S1535610824004434
  3. www.sciencedirect.com www.sciencedirect.com
    IL-17A/CEBPβ/OPN/LYVE-1 axis inhibits anti-tumor immunity by promoting tumor-associated tissue-resident macrophages
    1
    1. scibot 12 Dec 2024
      RRID:AB_1107780

      DOI: 10.1016/j.celrep.2024.115039

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    sciencedirect.com/science/article/pii/S2211124724013901
  4. www.sciencedirect.com www.sciencedirect.com
    A commonly inherited human PCSK9 germline variant drives breast cancer metastasis via LRP1 receptor
    1
    1. scibot 10 Dec 2024
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      DOI: 10.1016/j.cell.2024.11.009

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    sciencedirect.com/science/article/pii/S0092867424013266
  5. www.sciencedirect.com www.sciencedirect.com
    Flt3L enhances clonal diversification and selective expansion of intratumoral CD8+ T cells while differentiating into effector-like cells
    1
    1. scibot 02 Dec 2024
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      DOI: 10.1016/j.celrep.2024.115023

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    sciencedirect.com/science/article/pii/S2211124724013743
  6. Nov 2024
  7. www.sciencedirect.com www.sciencedirect.com
    Pericancerous cross-presentation to cytotoxic T lymphocytes impairs immunotherapeutic efficacy in hepatocellular carcinoma
    1
    1. scibot 21 Nov 2024
      RRID:AB_1107780

      DOI: 10.1016/j.ccell.2024.10.012

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    sciencedirect.com/science/article/pii/S1535610824004008
  8. 52.53.155.43 52.53.155.43
    can-24-0880-html.html
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    1. scibot 14 Nov 2024
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      DOI: 10.1158/0008-5472.can-24-0880

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    52.53.155.43/9e31c7f41d5a178619d25bd484dc4933596cae92/can-24-0880-html.html
  9. www.sciencedirect.com www.sciencedirect.com
    Itaconate transporter SLC13A3 impairs tumor immunity via endowing ferroptosis resistance
    1
    1. scibot 11 Nov 2024
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      DOI: 10.1016/j.ccell.2024.10.010

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    sciencedirect.com/science/article/pii/S1535610824003982
  10. www.sciencedirect.com www.sciencedirect.com
    Targeting the immune privilege of tumor-initiating cells to enhance cancer immunotherapy
    1
    1. scibot 11 Nov 2024
      RRID:AB_1107780

      DOI: 10.1016/j.ccell.2024.10.008

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    sciencedirect.com/science/article/pii/S1535610824003969
  11. journals.plos.org journals.plos.org
    Humoral and T-cell-mediated responses to an insect-specific flavivirus-based Zika virus vaccine candidate
    1
    1. scibot 07 Nov 2024
      RRID:AB_1107780

      DOI: 10.1371/journal.ppat.1012566

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    journals.plos.org/plospathogens/article
  12. Oct 2024
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Quiescence and aging of melanocyte stem cells and a novel association with PD-L1
    2
    1. scibot 05 Oct 2024
      RRID: AB_1107780

      DOI: 10.1016/j.isci.2024.110908

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    2. scibot 05 Oct 2024
      RRID:AB_1107780

      DOI: 10.1016/j.isci.2024.110908

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    ncbi.nlm.nih.gov/pmc/articles/PMC11440800/
  14. Sep 2024
  15. www.biorxiv.org www.biorxiv.org
    Beta cell extracellular vesicle PD-L1 as a novel regulator of CD8+ T cell activity and biomarker during the evolution of Type 1 Diabetes
    1
    1. scibot 28 Sep 2024
      RRID:AB_1107780

      DOI: 10.1101/2024.09.18.613649

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    biorxiv.org/content/10.1101/2024.09.18.613649v1
  16. www.sciencedirect.com www.sciencedirect.com
    A PD-1-targeted, receptor-masked IL-2 immunocytokine that engages IL-2Rα strengthens T cell-mediated anti-tumor therapies
    1
    1. scibot 27 Sep 2024
      AB_1107780

      DOI: 10.1016/j.xcrm.2024.101747

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    sciencedirect.com/science/article/pii/S2666379124004774
  17. www.sciencedirect.com www.sciencedirect.com
    Dietary vitamin B3 supplementation induces the antitumor immunity against liver cancer via biased GPR109A signaling in myeloid cell
    1
    1. scibot 25 Sep 2024
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      DOI: 10.1016/j.xcrm.2024.101718

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    sciencedirect.com/science/article/pii/S2666379124004397
  18. www.sciencedirect.com www.sciencedirect.com
    Junctional Adhesion Molecule 2 Represents a Subset of Hematopoietic Stem Cells with Enhanced Potential for T Lymphopoiesis
    1
    1. scibot 25 Sep 2024
      RRID:AB_1107780

      DOI: 10.1016/j.celrep.2019.05.028

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    sciencedirect.com/science/article/pii/S2211124719306394
  19. www.sciencedirect.com www.sciencedirect.com
    Glioblastoma induces the recruitment and differentiation of dendritic-like “hybrid” neutrophils from skull bone marrow
    1
    1. scibot 10 Sep 2024
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      DOI: 10.1016/j.ccell.2024.08.008

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    sciencedirect.com/science/article/pii/S1535610824003076
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Type I interferon signaling regulates myeloid and T cell crosstalk in the glioblastoma tumor microenvironment
    1
    1. scibot 04 Sep 2024
      AB_1107780

      DOI: 10.1016/j.isci.2024.110810

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    pmc.ncbi.nlm.nih.gov/articles/PMC11404196/
  21. Aug 2024
  22. www.sciencedirect.com www.sciencedirect.com
    PD-1 signaling limits expression of phospholipid phosphatase 1 and promotes intratumoral CD8+ T cell ferroptosis
    1
    1. scibot 29 Aug 2024
      RRID:AB_1107780

      DOI: 10.1016/j.immuni.2024.08.003

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    sciencedirect.com/science/article/pii/S1074761324003765
  23. www.sciencedirect.com www.sciencedirect.com
    Secreted PTEN binds PLXDC2 on macrophages to drive antitumor immunity and tumor suppression
    1
    1. scibot 28 Aug 2024
      AB_1107780

      DOI: 10.1016/j.devcel.2024.08.003

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    sciencedirect.com/science/article/pii/S1534580724004866
  24. www.sciencedirect.com www.sciencedirect.com
    Uncovering therapeutic targets for macrophage-mediated T cell suppression and PD-L1 therapy sensitization
    1
    1. scibot 27 Aug 2024
      AB_1107780

      DOI: 10.1016/j.xcrm.2024.101698

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    sciencedirect.com/science/article/pii/S2666379124004191
  25. www.sciencedirect.com www.sciencedirect.com
    The cytokine Meteorin-like inhibits anti-tumor CD8+ T cell responses by disrupting mitochondrial function
    2
    1. scibot 19 Aug 2024
      AB_1107780

      DOI: 10.1016/j.immuni.2024.07.003

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    2. scibot 13 Aug 2024
      AB_2616657

      DOI: 10.1016/j.immuni.2024.07.003

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    sciencedirect.com/science/article/pii/S1074761324003522
  26. Jul 2024
  27. www.science.org www.science.org
    Type I conventional dendritic cells facilitate immunotherapy in pancreatic cancer
    1
    1. scibot 25 Jul 2024
      RRID:AB_1107780

      DOI: 10.1126/science.adh4567

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    science.org/doi/10.1126/science.adh4567
  28. www.sciencedirect.com www.sciencedirect.com
    Transcriptional programming mediated by the histone demethylase KDM5C regulates dendritic cell population heterogeneity and function
    1
    1. scibot 25 Jul 2024
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      DOI: 10.1016/j.celrep.2024.114506

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    sciencedirect.com/science/article/pii/S2211124724008350
  29. www.cell.com www.cell.com
    Proteobacteria impair anti-tumor immunity in the omentum by consuming arginine
    1
    1. scibot 18 Jul 2024
      AB_1107780

      DOI: 10.1016/j.chom.2024.06.003

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    cell.com/cell-host-microbe/abstract/S1931-3128(24)00197-5
  30. www.sciencedirect.com www.sciencedirect.com
    Progestogen-driven B7-H4 contributes to onco-fetal immune tolerance
    1
    1. scibot 18 Jul 2024
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      DOI: 10.1016/j.cell.2024.06.012

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    sciencedirect.com/science/article/pii/S0092867424006524
  31. www.cell.com www.cell.com
    Cyclin dependent kinase 9 inhibition reduced programmed death-ligand 1 expression and improved treatment efficacy in hepatocellular carcinoma
    1
    1. scibot 12 Jul 2024
      RRID:AB_1107780

      DOI: 10.1016/j.heliyon.2024.e34289

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    cell.com/heliyon/fulltext/S2405-8440(24)10320-9
  32. Jun 2024
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stabilizing Tumor-Resident Mast Cells Restores T-Cell Infiltration and Sensitizes Sarcomas to PD-L1 Inhibition
    2
    1. scibot 07 Jun 2024
      RRID:AB_1107780

      DOI: 10.1158/1078-0432.CCR-24-0246

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    2. scibot 07 Jun 2024
      RRID:AB_1107780

      DOI: 10.1158/1078-0432.CCR-24-0246

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    ncbi.nlm.nih.gov/pmc/articles/PMC11145177/
  34. www.sciencedirect.com www.sciencedirect.com
    A CD36-dependent non-canonical lipid metabolism program promotes immune escape and resistance to hypomethylating agent therapy in AML
    1
    1. scibot 06 Jun 2024
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      DOI: 10.1016/j.xcrm.2024.101592

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    sciencedirect.com/science/article/pii/S2666379124002842
  35. www.sciencedirect.com www.sciencedirect.com
    Clonal hematopoiesis driven by mutated DNMT3A promotes inflammatory bone loss
    1
    1. scibot 05 Jun 2024
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      DOI: 10.1016/j.cell.2024.05.003

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    sciencedirect.com/science/article/pii/S0092867424004926
  36. www.sciencedirect.com www.sciencedirect.com
    Blockage of L2HGDH-mediated S-2HG catabolism orchestrates macrophage polarization to elicit antitumor immunity
    1
    1. scibot 04 Jun 2024
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      DOI: 10.1016/j.celrep.2024.114300

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    sciencedirect.com/science/article/pii/S2211124724006284
  37. May 2024
  38. www.sciencedirect.com www.sciencedirect.com
    Tumor cells impair immunological synapse formation via central nervous system-enriched metabolite
    2
    1. scibot 31 May 2024
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      DOI: 10.1016/j.ccell.2024.05.006

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    2. scibot 31 May 2024
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      DOI: 10.1016/j.ccell.2024.05.006

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    sciencedirect.com/science/article/pii/S1535610824001697
  39. www.sciencedirect.com www.sciencedirect.com
    Deletion of the mRNA endonuclease Regnase-1 promotes NK cell anti-tumor activity via OCT2-dependent transcription of Ifng
    2
    1. scibot 31 May 2024
      RRID:AB_1107780

      DOI: 10.1016/j.immuni.2024.05.006

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    2. scibot 31 May 2024
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      DOI: 10.1016/j.immuni.2024.05.006

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    sciencedirect.com/science/article/pii/S1074761324002590
  40. www.sciencedirect.com www.sciencedirect.com
    Circadian tumor infiltration and function of CD8+ T cells dictate immunotherapy efficacy
    1
    1. scibot 09 May 2024
      AB_1107780

      DOI: 10.1016/j.cell.2024.04.015

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    sciencedirect.com/science/article/pii/S0092867424004100
  41. Apr 2024
  42. www.sciencedirect.com www.sciencedirect.com
    Batf3+ DCs and the 4-1BB/4-1BBL axis are required at the effector phase in the tumor microenvironment for PD-1/PD-L1 blockade efficacy
    1
    1. scibot 24 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114141

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    sciencedirect.com/science/article/pii/S2211124724004698
  43. www.sciencedirect.com www.sciencedirect.com
    QDPR deficiency drives immune suppression in pancreatic cancer
    1
    1. scibot 23 Apr 2024
      RRID:AB_1107780

      DOI: 10.1016/j.cmet.2024.03.015

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    sciencedirect.com/science/article/pii/S1550413124001190
  44. www.sciencedirect.com www.sciencedirect.com
    Tim4 enables large peritoneal macrophages to cross-present tumor antigens at early stages of tumorigenesis
    1
    1. scibot 18 Apr 2024
      RRID:AB_1107780

      DOI: 10.1016/j.celrep.2024.114096

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    sciencedirect.com/science/article/pii/S2211124724004248
  45. www.sciencedirect.com www.sciencedirect.com
    CXCL9/10-engineered dendritic cells promote T cell activation and enhance immune checkpoint blockade for lung cancer
    1
    1. scibot 12 Apr 2024
      RRID:AB_1107780

      DOI: 10.1016/j.xcrm.2024.101479

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    sciencedirect.com/science/article/pii/S2666379124001253
  46. www.nature.com www.nature.com
    Targeting branched N-glycans and fucosylation sensitizes ovarian tumors to immune checkpoint blockade
    1
    1. scibot 03 Apr 2024
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      DOI: 10.1038/s41467-024-47069-y

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    nature.com/articles/s41467-024-47069-y
  47. Mar 2024
  48. www.sciencedirect.com www.sciencedirect.com
    Retinoic acid receptor activation reprograms senescence response and enhances anti-tumor activity of natural killer cells
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  49. Feb 2024
  50. www.sciencedirect.com www.sciencedirect.com
    UFL1 ablation in T cells suppresses PD-1 UFMylation to enhance anti-tumor immunity
    1
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  51. 52.53.155.43 52.53.155.43
    Scarring hair follicle destruction is driven by the collapse of EGFR-protected JAK-STAT1-sensitive stem cell immune privilege
    1
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  52. www.sciencedirect.com www.sciencedirect.com
    Signaling via a CD27-TRAF2-SHP-1 axis during naive T cell activation promotes memory-associated gene regulatory networks
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    Tumor-secreted FGF21 acts as an immune suppressor by rewiring cholesterol metabolism of CD8+T cells
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    Amphiregulin from regulatory T cells promotes liver fibrosis and insulin resistance in non-alcoholic steatohepatitis
    2
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  55. Jan 2024
  56. www.sciencedirect.com www.sciencedirect.com
    Interrogation of endothelial and mural cells in brain metastasis reveals key immune-regulatory mechanisms
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  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DNA damage repair profiling of esophageal squamous cell carcinoma uncovers clinically relevant molecular subtypes with distinct prognoses and therapeutic vulnerabilities
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  58. www.sciencedirect.com www.sciencedirect.com
    Skin microbe-dependent TSLP-ILC2 priming axis in early life is co-opted in allergic inflammation
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    Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T cells
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  60. Dec 2023
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    More time to kill: a longer liver stage increases T cell-mediated protection against pre-erythrocytic malaria
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  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Helicobacter pylori CagA promotes immune evasion of gastric cancer by upregulating PD-L1 level in exosomes
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  63. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Early cellular mechanisms of type I interferon-driven susceptibility to tuberculosis
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    The tumor-derived cytokine Chi3l1 induces neutrophil extracellular traps that promote T cell exclusion in triple-negative breast cancer
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  65. Nov 2023
  66. link.springer.com link.springer.com
    Trans-vaccenic acid reprograms CD8+ T cells and anti-tumour immunity
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      RRID:AB_1107780

      DOI: 10.1038/s41586-023-06749-3

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    A SOX9-B7x axis safeguards dedifferentiated tumor cells from immune surveillance to drive breast cancer progression
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    PD-L1-mediated immune evasion in triple-negative breast cancer is linked to the loss of ZNF652
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  69. Oct 2023
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    Kruppel-like factor 2+ CD4 T cells avert microbiota-induced intestinal inflammation
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    Dietary fructose-mediated adipocyte metabolism drives antitumor CD8+ T cell responses
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    Intermittent fasting induced ketogenesis inhibits mouse epithelial ovarian cancer by promoting antitumor T cell response
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    Oncolytic virus M1 functions as a bifunctional checkpoint inhibitor to enhance the antitumor activity of DC vaccine
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    Genetic and pharmaceutical targeting of HIF1α allows combo-immunotherapy to boost graft vs. leukemia without exacerbation graft vs. host disease
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    Supplementation with a high-glucose drink stimulates anti-tumor immune responses to glioblastoma via gut microbiota modulation
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    Upregulation of exosome secretion from tumor-associated macrophages plays a key role in the suppression of anti-tumor immunity
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    Glioblastoma vascular plasticity limits effector T-cell infiltration and is blocked by cAMP activation
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      DOI: 10.1158/2326-6066.CIR-22-0872

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    Endothelial cells are a key target of IFN-g during response to combined PD-1/CTLA-4 ICB treatment in a mouse model of bladder cancer
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  79. Sep 2023
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    Molecular, metabolic, and functional CD4 T cell paralysis in the lymph node impedes tumor control
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  81. Aug 2023
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activating Inducible T cell Co-stimulator (ICOS) yields anti-tumor activity alone and in combination with anti-PD-1 checkpoint blockade
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      DOI: 10.1158/2767-9764.CRC-22-0293

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  83. 52.53.155.43 52.53.155.43
    Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8+ T cell exhaustion via TRIM14-IFN-β axis
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  84. 52.53.155.43 52.53.155.43
    CD39 inhibition and VISTA blockade may overcome radiotherapy resistance by targeting exhausted CD8+ T cells and immunosuppressive myeloid cells
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    A CSF-1R-blocking antibody/IL-10 fusion protein increases anti-tumor immunity by effectuating tumor-resident CD8+ T cells
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    Membrane-localized neoantigens predict the efficacy of cancer immunotherapy
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  87. Jun 2023
  88. www.sciencedirect.com www.sciencedirect.com
    PD-L1/PD-1 checkpoint pathway regulates hippocampal neuronal excitability and learning and memory behavior
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    RORψt+CD4+ T cells promote IL-23R-mediated neuronal cell apoptosis in the central nervous system
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  90. May 2023
  91. www.sciencedirect.com www.sciencedirect.com
    CCL19+ dendritic cells potentiate clinical benefit of anti-PD-(L)1 immunotherapy in triple-negative breast cancer
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    The glycolysis/HIF-1α axis defines the inflammatory role of IL-4-primed macrophages
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  93. Apr 2023
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    The gut microbiota promotes distal tissue regeneration via RORγ+ regulatory T cell emissaries
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    Targeting the mevalonate pathway suppresses ARID1A-inactivated cancers by promoting pyroptosis
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    Targeting USP2 regulation of VPRBP-mediated degradation of p53 and PD-L1 for cancer therapy
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  97. www.cell.com www.cell.com
    Dietary tryptophan metabolite released by intratumoral Lactobacillus reuteri facilitates immune checkpoint inhibitor treatment
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    Targeting protein tyrosine phosphatases for CDK6-induced immunotherapy resistance
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  99. Mar 2023
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    LCN2 secreted by tissue-infiltrating neutrophils induces the ferroptosis and wasting of adipose and muscle tissues in lung cancer cachexia
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    ILC3s restrict the dissemination of intestinal bacteria to safeguard liver regeneration after surgery
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    IFNγ is a central node of cancer immune equilibrium
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    Fc glycoengineering of a PD-L1 antibody harnesses Fcγ receptors for increased antitumor efficacy
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  104. Feb 2023
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    Interplay between liver and blood stages of Plasmodium infection dictates malaria severity via γδ T cells and IL-17-promoted stress erythropoiesis
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    Circumvention of luteolysis reveals parturition pathways in mice dependent upon innate type 2 immunity
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    KDM5A Inhibits Antitumor Immune Responses Through Downregulation of the Antigen-Presentation Pathway in Ovarian Cancer
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  108. Jan 2023
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    Neutrophil-activating therapy for the treatment of cancer
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    MHC class II-restricted antigen presentation is required to prevent dysfunction of cytotoxic T cells by blood-borne myeloids in brain tumors
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    Intersection of immune and oncometabolic pathways drives cancer hyperprogression during immunotherapy
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    Non-canonical inflammasome activation mediates the adjuvanticity of nanoparticles
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    Flt3- and Tie2-Cre tracing identifies regeneration in sepsis from multipotent progenitors but not hematopoietic stem cells
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    Microbiota-dependent and -independent postnatal development of salivary immunity
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    Immune checkpoint therapy-elicited sialylation of IgG antibodies impairs antitumorigenic type I interferon responses in hepatocellular carcinoma
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  116. Dec 2022
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    Hyaluronan driven by epithelial aPKC deficiency remodels the microenvironment and creates a vulnerability in mesenchymal colorectal cancer
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    Original research: Targeting of Cdc42 GTPase in regulatory T cells unleashes antitumor T-cell immunity
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  119. Nov 2022
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    STAT3 gain-of-function mutations connect leukemia with autoimmune disease by pathological NKG2Dhi CD8+ T cell dysregulation and accumulation
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    Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1+ T lymphocyte niches through a feed-forward loop
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    The transcription factor IRF2 drives interferon-mediated CD8+ T cell exhaustion to restrict anti-tumor immunity
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    Obesity enhances antiviral immunity in the genital mucosa through a microbiota-mediated effect on γδ T cells
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    Tumor-intrinsic SIRPA promotes sensitivity to checkpoint inhibition immunotherapy in melanoma
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  125. Oct 2022
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    Expansion of T memory stem cells with superior anti-tumor immunity by Urolithin A-induced mitophagy
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    NOTCH induced MDSC recruitment after oHSV virotherapy in CNS cancer models modulates anti-tumor immunotherapy
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      DOI: 10.1158/1078-0432.CCR-21-2347

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  128. Sep 2022
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    The ketone body β-hydroxybutyrate mitigates ILC2-driven airway inflammation by regulating mast cell function
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  130. Jul 2022
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    Group 3 innate lymphocytes make a distinct contribution to Type 17 immunity in bladder defence
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  133. Jun 2022
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    Proinflammatory signaling in islet β cells propagates invasion of pathogenic immune cells in autoimmune diabetes
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    PGE2-EP2/EP4 signaling elicits immunosuppression by driving the mregDC-Treg axis in inflammatory tumor microenvironment
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  136. May 2022
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    WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC
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    Topical therapy for regression and melanoma prevention of congenital giant nevi
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    Lymph node colonization induces tumor-immune tolerance to promote distant metastasis
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  140. Apr 2022
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    Immunosuppressive tumor microenvironment in Uterine Serous Carcinoma via CCL7 signal with myeloid-derived suppressor cells
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      DOI: 10.1093/carcin/bgac032

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  142. Mar 2022
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    The microbial metabolite trimethylamine N-oxide promotes antitumor immunity in triple-negative breast cancer
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    Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity
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    Tumor-associated high endothelial venules mediate lymphocyte entry into tumors and predict response to PD-1 plus CTLA-4 combination immunotherapy
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    Glucocorticoid receptor regulates PD-L1 and MHC-I in pancreatic cancer cells to promote immune evasion and immunotherapy resistance
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  154. Oct 2021
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    Cold exposure protects from neuroinflammation through immunologic reprogramming
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  156. Sep 2021
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    Live Imaging of SARS-CoV-2 Infection in Mice Reveals that Neutralizing Antibodies Require Fc Function for Optimal Efficacy
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    Effector T cell responses unleashed by regulatory T cell ablation exacerbate oral squamous cell carcinoma
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    Identification of a Locus in Mice that Regulates the Collateral Damage and Lethality of Virus Infection
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    Checkpoint Blockade Immunotherapy Induces Dynamic Changes in PD-1−CD8+ Tumor-Infiltrating T Cells
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  166. Jul 2021
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    Colitis-Induced Th17 Cells Increase the Risk for Severe Subsequent Clostridium difficile Infection
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    Type I Interferon Delivery by iPSC-Derived Myeloid Cells Elicits Antitumor Immunity via XCR1+ Dendritic Cells
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      InVivoMab rat IgG2b isotype control clone LTF-2

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    T Helper Cell Cytokines Modulate Intestinal Stem Cell Renewal and Differentiation
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    Interferon-α-producing plasmacytoid dendritic cells drive the loss of adipose tissue regulatory T cells during obesity
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  178. May 2021
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    Inhibition of Glutamine Utilization Synergizes with Immune Checkpoint Inhibitor to Promote Antitumor Immunity
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    Production of the Cytokine VEGF-A by CD4+ T and Myeloid Cells Disrupts the Corneal Nerve Landscape and Promotes Herpes Stromal Keratitis
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    Adoptive T Cell Therapy Targeting Different Gene Products Reveals Diverse and Context-Dependent Immune Evasion in Melanoma
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  186. Apr 2021
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    Sirt2 Inhibition Enhances Metabolic Fitness and Effector Functions of Tumor-Reactive T Cells
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    HSP90 Inhibition Enhances Cancer Immunotherapy by Modulating the Surface Expression of Multiple Immune Checkpoint Proteins
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    CD36-mediated ferroptosis dampens intratumoral CD8+ T cell effector function and impairs their antitumor ability
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    Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity
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    The Intestinal Microbiome Restricts Alphavirus Infection and Dissemination through a Bile Acid-Type I IFN Signaling Axis
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    Stanniocalcin 1 is a phagocytosis checkpoint driving tumor immune resistance
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  195. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting obesity-induced macrophages during preneoplastic growth promotes mammary epithelial stem/progenitor activity, DNA damage and tumor formation
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  196. Nov 2020
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    Therapeutic Role of Inducible Nitric Oxide Synthase Expressing Myeloid-Derived Suppressor Cells in Acetaminophen-Induced Murine Liver Failure
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    Antibody Feedback Limits the Expansion of B Cell Responses to Malaria Vaccination but Drives Diversification of the Humoral Response
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  200. Sep 2020
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    GM-CSF Calibrates Macrophage Defense and Wound Healing Programs during Intestinal Infection and Inflammation
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    Mutant EZH2 Induces a Pre-malignant Lymphoma Niche by Reprogramming the Immune Response
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    Decidual NK Cells Transfer Granulysin to Selectively Kill Bacteria in Trophoblasts
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    TRPM5 Negatively Regulates Calcium-Dependent Responses in Lipopolysaccharide-Stimulated B Lymphocytes
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    Dysregulated Expression of the Nuclear Exosome Targeting Complex Component Rbm7 in Nonhematopoietic Cells Licenses the Development of Fibrosis
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    Ablation of Transcription Factor IRF4 Promotes Transplant Acceptance by Driving Allogenic CD4+ T Cell Dysfunction
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    Dendritic Cell Paucity Leads to Dysfunctional Immune Surveillance in Pancreatic Cancer
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    Th1-Th2 Cross-Regulation Controls Early Leishmania Infection in the Skin by Modulating the Size of the Permissive Monocytic Host Cell Reservoir
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    CD4+ T Cells Cross-Reactive with Dengue and Zika Viruses Protect against Zika Virus Infection
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    Hookworms Evade Host Immunity by Secreting a Deoxyribonuclease to Degrade Neutrophil Extracellular Traps
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    ADORA1 Inhibition Promotes Tumor Immune Evasion by Regulating the ATF3-PD-L1 Axis
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    PD-1 Inhibitory Receptor Downregulates Asparaginyl Endopeptidase and Maintains Foxp3 Transcription Factor Stability in Induced Regulatory T Cells
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      Rat-IgG2b Isotype Control (LTF-2)

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  215. Jan 2020
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    CDK7 Inhibition Potentiates Genome Instability Triggering Anti-tumor Immunity in Small Cell Lung Cancer
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    PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways
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    EphA2 Is a Neutrophil Receptor for Candida albicans that Stimulates Antifungal Activity during Oropharyngeal Infection
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    PD-1 Signaling Promotes Control of Chronic Viral Infection by Restricting Type-I-Interferon-Mediated Tissue Damage
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    Neutrophil Extracellular Traps Initiate Gallstone Formation
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    Proliferating Transitory T Cells with an Effector-like Transcriptional Signature Emerge from PD-1+ Stem-like CD8+ T Cells during Chronic Infection
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    Blocking Antibodies Targeting the CD39/CD73 Immunosuppressive Pathway Unleash Immune Responses in Combination Cancer Therapies
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    The Chemoattractant Receptor Ebi2 Drives Intranodal Naive CD4+ T Cell Peripheralization to Promote Effective Adaptive Immunity
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    Staphylococcus aureus Leukocidins Target Endothelial DARC to Cause Lethality in Mice
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    Colitis-Induced Th17 Cells Increase the Risk for Severe Subsequent Clostridium difficile Infection
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    Suppression of Exosomal PD-L1 Induces Systemic Anti-tumor Immunity and Memory
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