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Restoration of Lysosomal Hydrolase Activities by LRRK2 Inhibition in GBA1- and LRRK2-Associated Parkinson's Disease Patient-Derived Cells

1
1. scibot 09 Sep 2025
  
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  RRID:AB_2313773
  
  DOI: 10.1111/jnc.70214
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.70214
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Investigating cochlear cellular dynamics in neurofibromatosis type 2-associated schwannomatosis: a histopathological study

1
1. scibot 07 Sep 2025
  
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  RRID:AB_2313773
  
  DOI: 10.3389/fneur.2025.1650470
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12394883/
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Effect of henagliflozin on aging biomarkers in patients with type 2 diabetes: A multicenter, randomized, double-blind, placebo-controlled study

1
1. scibot 06 Sep 2025
  
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  RRID:AB_2313773
  
  DOI: 10.1016/j.xcrm.2025.102331
  
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sciencedirect.com/science/article/pii/S2666379125004045
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Feature-driven whole-tissue imaging with subcellular resolution

1
1. scibot 03 Sep 2025
  
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  RRID:AB_2313773
  
  DOI: 10.1016/j.crmeth.2025.101148
  
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sciencedirect.com/science/article/pii/S2667237525001845
Aug 2025
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Generation of patient-derived and gene-corrected hiPSC lines from Hereditary Hemorrhagic Telangiectasia type 2 patients with ACVRL1 c.1042delG mutation

1
1. scibot 26 Aug 2025
  
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  AB_2313773
  
  DOI: 10.1016/j.scr.2025.103812
  
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sciencedirect.com/science/article/pii/S187350612500162X
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Activation of polo-like kinase 1 correlates with selective motor neuron vulnerability in familial ALS

1
1. scibot 26 Aug 2025
  
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  RRID:AB_2313773
  
  DOI: 10.1016/j.celrep.2025.116113
  
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sciencedirect.com/science/article/pii/S2211124725008848
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Molecular and spatial analysis of ganglion cells on retinal flatmounts identifies perivascular neurons resilient to glaucoma

1
1. scibot 21 Aug 2025
  
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  RRID:AB_2728521
  
  DOI: 10.1016/j.neuron.2025.07.025
  
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sciencedirect.com/science/article/pii/S0896627325005525
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Generation of three human induced pluripotent stem cell (hiPSC) lines from patients with Late-Onset Tay-Sachs disease (HEXA-related adult-onset GM2-gangliosidosis)

1
1. scibot 13 Aug 2025
  
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  RRID:AB_10063408
  
  DOI: 10.1016/j.scr.2025.103801
  
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sciencedirect.com/science/article/pii/S1873506125001515
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The Nα-acetyl-L-lysine/Loxl2/H2O2 promotes intestinal tumor growth in Drosophila and cell proliferation in human colorectal cancer

1
1. scibot 13 Aug 2025
  
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  RRID:AB_2313773
  
  DOI: 10.1016/j.celrep.2025.116126
  
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sciencedirect.com/science/article/pii/S2211124725008976
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Generation of three iPSC lines from patients with CACNA1S related congenital myopathy

1
1. scibot 09 Aug 2025
  
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  RRID:AB_2313773
  
  DOI: 10.1016/j.scr.2025.103796
  
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sciencedirect.com/science/article/pii/S1873506125001461
www.cell.com www.cell.com

Chemical reprogramming of human blood cells to pluripotent stem cells

1
1. scibot 05 Aug 2025
  
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  RRID:AB_2313773
  
  DOI: 10.1016/j.stem.2025.07.003
  
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cell.com/cell-stem-cell/abstract/S1934-5909(25)00260-7
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Prediction of the hypothalamus-pituitary organoid formation using machine learning

1
1. scibot 05 Aug 2025
  
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  RRID:AB_2313773
  
  DOI: 10.1016/j.crmeth.2025.101119
  
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sciencedirect.com/science/article/pii/S2667237525001559
Jul 2025
52.53.155.43 52.53.155.43

watanabe-et-al-als-associated-rna-binding-proteins-promote-unc13a-transcription-through-rest-downregulation-html.html

1
1. scibot 30 Jul 2025
  
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  AB_2313773
  
  DOI: 10.1038/s44318-025-00506-0
  
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52.53.155.43/42423fb21c90eb6b2282f89153f3787d8f44c56d/watanabe-et-al-als-associated-rna-binding-proteins-promote-unc13a-transcription-through-rest-downregulation-html.html
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Protocol for direct reprogramming of canine fibroblasts to induced motor neurons

1
1. scibot 29 Jul 2025
  
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  RRID:AB_2728521
  
  DOI: 10.1016/j.xpro.2025.103975
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12311591/
www.biorxiv.org www.biorxiv.org

Fusiform Cells in the Dorsal Cochlear Nucleus Change Intrinsic Electrophysiological Properties and Morphologically Remodel Their Basal Dendrites with Age

1
1. scibot 25 Jul 2025
  
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  RRID:AB_2313773
  
  DOI: 10.1101/2025.07.16.665173
  
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biorxiv.org/content/10.1101/2025.07.16.665173v1
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Enhancing transcriptome mapping with rapid PRO-seq profiling of nascent RNA

1
1. scibot 25 Jul 2025
  
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  RRID:AB_2313773
  
  DOI: 10.1016/j.molcel.2025.06.029
  
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sciencedirect.com/science/article/pii/S1097276525005799
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Epigenome profiling identifies H3K27me3 regulation of extracellular matrix composition in human corticogenesis

1
1. scibot 23 Jul 2025
  
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  RRID:AB_2313773
  
  DOI: 10.1016/j.neuron.2025.06.016
  
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sciencedirect.com/science/article/pii/S089662732500474X
www.biorxiv.org www.biorxiv.org

Taste dysfunction in Long COVID

1
1. scibot 22 Jul 2025
  
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  RRID:AB_2313773
  
  DOI: 10.1101/2025.07.17.661973
  
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biorxiv.org/content/10.1101/2025.07.17.661973v1
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Generation of an iPSC line from congenital hypopituitarism patient with a nonsense heterozygous variant in FOXA2

1
1. scibot 19 Jul 2025
  
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  RRID:AB_2313773
  
  DOI: 10.1016/j.scr.2025.103777
  
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sciencedirect.com/science/article/pii/S1873506125001278
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Spiner, deep learning-based automated detection of spiral ganglion neurons in intact cochleae

1
1. scibot 15 Jul 2025
  
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  RRID:AB_2313773
  
  DOI: 10.1016/j.isci.2025.112929
  
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sciencedirect.com/science/article/pii/S2589004225011903
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The association between cystatin C and hypertension risk in diabetes patients: A multi-cohort cross-sectional study

1
1. scibot 08 Jul 2025
  
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  RRID:AB_2313773
  
  DOI: 10.1016/j.isci.2025.112979
  
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sciencedirect.com/science/article/pii/S2589004225012404
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Delayed forebrain excitatory and inhibitory neurogenesis in STRADA-related megalencephaly via mTOR hyperactivity

1
1. scibot 15 Jun 2025
  
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  RRID:AB_2313773
  
  DOI: 10.1101/2025.05.13.653911
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12132401/
www.cell.com www.cell.com

Quiescent horizontal basal stem cells act as a niche for olfactory neurogenesis in a mouse 3D organoid model

1
1. scibot 15 Jun 2025
  
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  RRID:AB_2313773
  
  DOI: 10.1016/j.crmeth.2025.101055
  
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cell.com/cell-reports-methods/fulltext/S2667-2375(25)00091-8
www.cell.com www.cell.com

Derepressing nuclear pyruvate dehydrogenase induces therapeutic cancer cell reprogramming

1
1. scibot 11 Jun 2025
  
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  RRID:AB_2313773
  
  DOI: 10.1016/j.cmet.2025.05.009
  
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cell.com/cell-metabolism/abstract/S1550-4131(25)00265-7
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Synaptic activity causes minute-scale changes in BAF complex composition and function

1
1. scibot 11 Jun 2025
  
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  RRID:AB_2313773
  
  DOI: 10.1016/j.molcel.2025.05.017
  
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sciencedirect.com/science/article/pii/S1097276525004563
May 2025
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GADD45G operates as a pathological sensor orchestrating reactive gliosis and neurodegeneration

1
1. scibot 29 May 2025
  
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  RRID:AB_2313773
  
  DOI: 10.1016/j.neuron.2025.04.033
  
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sciencedirect.com/science/article/pii/S0896627325003459
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A Novel Phosphorylated Tau Conformer Implicated in the Tauopathy Pathogenesis of Human Neurons

1
1. scibot 21 May 2025
  
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  RRID:AB_2313773
  
  DOI: 10.3390/biom15040585
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12025006/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

hiPSC-neurons recapitulate the subtype-specific cell intrinsic nature of susceptibility to neurodegenerative disease-relevant aggregation

1
1. scibot 21 May 2025
  
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  AB_2313773
  
  DOI: 10.1186/s40478-025-02000-4
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12087151/
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Generation of human induced pluripotent stem cell lines from two down syndrome patients, including a down syndrome/Alzheimer’s disease case (FLENIi002-A) and a beta-amyloid-resistant case (FLENIi003-A)

1
1. scibot 18 May 2025
  
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  AB_2313773
  
  DOI: 10.1016/j.scr.2025.103728
  
  Resource: (BioLegend Cat# 801201, RRID:AB_2313773)
  
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sciencedirect.com/science/article/pii/S1873506125000789
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Generation of human induced pluripotent stem cell lines HUJIi004 and HUJIi005 from two individuals carrying autosomal-dominant mutations in the CTNBB1 gene resulting in CTNNB1 neurodevelopmental disorder

1
1. scibot 18 May 2025
  
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  AB_2313773
  
  DOI: 10.1016/j.scr.2025.103667
  
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sciencedirect.com/science/article/pii/S1873506125000170
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Enhanced differentiation of neural progenitor cells in Alzheimer’s disease into vulnerable immature neurons

1
1. scibot 18 May 2025
  
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  RRID:AB_2313773
  
  DOI: 10.1016/j.isci.2025.112446
  
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sciencedirect.com/science/article/pii/S2589004225007072
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Repeat-element RNAs integrate a neuronal growth circuit

1
1. scibot 17 May 2025
  
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  RRID:AB_2313773
  
  DOI: 10.1016/j.cell.2025.04.030
  
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sciencedirect.com/science/article/pii/S0092867425004982
Apr 2025
52.53.155.43 52.53.155.43

1-s2.0-S1525001625002941-main-html.html

1
1. scibot 24 Apr 2025
  
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  RRID:AB_23137
  
  DOI: 10.1016/j.ymthe.2025.04.020
  
  Resource: None
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:AB_2313773
  
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  RRID:AB_2313773 RRIDCUR:Unresolved
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52.53.155.43/62a2f6c8628763245253eabaf4b28b782b5ff84c/1-s2.0-S1525001625002941-main-html.html
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Enteric glia regulate Paneth cell secretion and intestinal microbial ecology

1
1. scibot 16 Apr 2025
  
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  RRID:AB_2313773
  
  DOI: 10.7554/eLife.97144
  
  Resource: (BioLegend Cat# 801201, RRID:AB_2313773)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11996175/
52.53.155.43 52.53.155.43

1-s2.0-S2589004225006169-main-html.html

2
1. scibot 10 Apr 2025
  
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  RRID:AB_2313773
  
  DOI: 10.1016/j.isci.2025.112355
  
  Resource: (BioLegend Cat# 801201, RRID:AB_2313773)
  
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  RRID:AB_2313773
2. scibot 08 Apr 2025
  
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  RRID:AB_2313773
  
  DOI: 10.1016/j.isci.2025.112355
  
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Harmine promotes axon regeneration through enhancing glucose metabolism

1
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Heroin Regulates the Voltage-Gated Sodium Channel Auxiliary Subunit, SCN1b, to Modulate Nucleus Accumbens Medium Spiny Neuron Intrinsic Excitability and Cue-Induced Heroin Seeking

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A transcriptional atlas of gut-innervating neurons reveals activation of interferon signaling and ferroptosis during intestinal inflammation

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Protective ApoE variants support neuronal function by extracting peroxidated lipids

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Protocol for generating human cerebral organoids from two-dimensional cultures of pluripotent stem cells bypassing embryoid body aggregation

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Local keratinocyte-nociceptor interactions enhance obesity-mediated painful small fiber neuropathy via NGF-TrkA-PI3K signaling axis

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Compact transcription factor cassettes generate functional, engraftable motor neurons by direct conversion

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Proliferation history and transcription factor levels drive direct conversion to motor neurons

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Translatome analysis reveals cellular network in DLK-dependent hippocampal glutamatergic neuron degeneration

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Single extracellular vesicle detection assay identifies membrane-associated α-synuclein as an early-stage biomarker in Parkinson’s disease

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Novel CRISPR-Cas9 iPSC knockouts for PCCA and PCCB genes: advancing propionic acidemia research

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TRIM46 is required for microtubule fasciculation in vivo but not axon specification or axon initial segment formation

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Oxidative Stress Suppresses Trk Signaling While Stimulating JNK-Mediated Endocytosis and Cleavage of p75NTR: A Targetable Pathway for Neuroprotection in a Parkinson's Disease Model

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awaf051-html.html

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Harmine promotes axon regeneration through enhancing glucose metabolism

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A developmental atlas of mouse vestibular-like inner ear organoids

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Measuring Protein Nuclear Transport via a Dual Reporter in iPSC-Derived Neurons

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Preparation of Highly Pure hiPSC-Derived Motor Neurons Through Assembling a Co-culture System

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Generation of Motor Neurons from Human Induced Pluripotent Stem Cells Using Small Chemical Molecules

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Mina53 catalyzes arginine demethylation of p53 to promote tumor growth

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Kinesin-like motor protein KIF23 maintains neural stem and progenitor cell pools in the developing cortex

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Phospho-regulation of ASCL1-mediated chromatin opening during cellular reprogramming

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Biotin mitigates the development of manganese-induced, Parkinson’s disease–related neurotoxicity in Drosophila and human neurons

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Unbiased identification of cell identity in dense mixed neural cultures

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Placode and neural crest origins of congenital deafness in mouse models of Waardenburg-Shah syndrome

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Blood-derived APLP1+ extracellular vesicles are potential biomarkers for the early diagnosis of brain diseases

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Blood-derived APLP1+ extracellular vesicles are potential biomarkers for the early diagnosis of brain diseases

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Generation of three human induced pluripotent stem cell lines from retinitis pigmentosa 25 patient and two carriers but asymptomatic daughters

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Cyclin O controls entry into the cell-cycle variant required for multiciliated cell differentiation

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Dec 2024
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PDF-html.html

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Intrinsic adaptive plasticity in mouse and human sensory neurons

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Persistence of spike protein at the skull-meninges-brain axis may contribute to the neurological sequelae of COVID-19

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Development of MAPT S305 mutation human iPSC lines exhibiting elevated 4R tau expression and functional alterations in neurons and astrocytes

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Netrin1 patterns the dorsal spinal cord through modulation of Bmp signaling

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Protocol for analyzing the function of the type VI secretion system of the oral symbiont Aggregatibacter aphrophilus in targeting pathobionts

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SNARE protein SNAP25 regulates the chloride-transporter KCC2 in neurons

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Generation and characterization of two isogenic induced pluripotent stem cell lines from a young female with microcephaly carrying a compound heterozygous mutation in BUB1 gene

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Local glycolysis supports injury-induced axonal regeneration

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Microbiota-dependent early-life programming of gastrointestinal motility

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Targeting vasohibins to promote axon regeneration

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SOX10 mediates glioblastoma cell-state plasticity

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Axon guidance during mouse central nervous system regeneration is required for specific brain innervation

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LM11a-31 Inhibits p75 Neurotrophin Receptor (p75NTR) Cleavage and is Neuroprotective in a Cell Culture Model of Parkinson’s Disease

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Targeting the PAC1 receptor mitigates degradation of myelin and synaptic markers and diminishes locomotor deficits in the cuprizone demyelination model

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Epitranscriptomic m6A Regulation of Axon Regeneration in the Adult Mammalian Nervous System

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Generation of homozygous CRISPRa human induced pluripotent stem cell (hiPSC) lines for sustained endogenous gene activation

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TAG-1 Multifunctionality Coordinates Neuronal Migration, Axon Guidance, and Fasciculation

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Modeling Progressive Fibrosis with Pluripotent Stem Cells Identifies an Anti-fibrotic Small Molecule

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Heterogeneity within Stratified Epithelial Stem Cell Populations Maintains the Oral Mucosa in Response to Physiological Stress

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PI4KB on Inclusion Bodies Formed by ER Membrane Remodeling Facilitates Replication of Human Parainfluenza Virus Type 3

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Untitled document

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Untitled document

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The dynamics of native Atoh7 protein expression during mouse retinal histogenesis, revealed with a new antibody

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Generation of human induced pluripotent stem cell lines from a subject with UBAP1L-associated retinal dystrophy and CRISPR/cas9-corrected isogenic iPSC lines

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Development of a 3-dimensional organotypic model with characteristics of peripheral sensory nerves

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Reproducible Differentiation of Human Pluripotent Stem Cells into Two-Dimensional Cortical Neuron Cultures with Checkpoints for Success

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Studying Pathogenetic Contribution of a Variant of Unknown Significance, p.M659I (c.1977G > A) in MYH7, to the Development of Hypertrophic Cardiomyopathy Using CRISPR/Cas9-Engineered Isogenic Induced Pluripotent Stem Cells

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ATAXIN-2 intermediate-length polyglutamine expansions elicit ALS-associated metabolic and immune phenotypes

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GABAergic neuronal lineage development determines clinically actionable targets in diffuse hemispheric glioma, H3G34-mutant

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Generation of a heterozygous Calsequestrin 2 F189L iPSC line (UMGi158-B) by CRISPR/Cas9 genome editing to investigate the cardiac pathophysiology of Takotsubo Syndrome and Catecholaminergic Polymorphic ventricular Tachycardia

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The RNA-binding protein EIF4A3 promotes axon development by direct control of the cytoskeleton

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ARNT2 controls prefrontal somatostatin interneurons mediating affective empathy

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Developmental shaping of node of Ranvier geometry contributes to spike timing maturation in primary auditory afferents

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The tyrosine phosphatases LAR and PTPRδ act as receptors of the nidogen-tetanus toxin complex

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Rapid phagosome isolation enables unbiased multiomic analysis of human microglial phagosomes

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A glia-enriched stem cell 3D model of the human brain mimics the glial-immune neurodegenerative phenotypes of multiple sclerosis

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Sigma-1 receptor targeting inhibits connexin 43 based intercellular communication in chronic neuropathic pain

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Nogo‐B is the major form of Nogo at the floor plate and likely mediates crossing of commissural axons in the mouse spinal cord

1
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  DOI: 10.1002/cne.24246
  
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Rapid iPSC inclusionopathy models shed light on formation, consequence, and molecular subtype of α-synuclein inclusions

1
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PTEN acts as a crucial inflammatory checkpoint controlling TLR9/IL-6 axis in B cells

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Cleaner heating policies contribute significantly to health benefits and cost-savings: A case study in Beijing, China

1
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Selective targeting of mu opioid receptors to primary cilia

1
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CXCL3/TGF-β-Mediated Crosstalk Between CAFs and Tumor Cells Augments RCC Progression and Sunitinib Resistance

1
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Hyperactivation of MEK1 in cortical glutamatergic neurons results in projection axon deficits and aberrant motor learning

1
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  DOI: 10.1242/dmm.050570
  
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Comparative transcriptomic profiling reveals a role for Olig1 in promoting axon regeneration

1
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The tyrosine phosphatases LAR and PTPRδ act as receptors of the nidogen-tetanus toxin complex

1
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Depletion of Mettl3 in cholinergic neurons causes adult-onset neuromuscular degeneration

1
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Sustained generation of neurons destined for neocortex with oxidative metabolic upregulation upon filamin abrogation

1
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Generation of human induced pluripotent stem cell lines (LUMCi051-A,B and LUMCi052-A,B,C) of two patients with Spinocerebellar ataxia type 7

1
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The presenilin 1 mutation P436S causes familial Alzheimer's disease with elevated Aβ43 and atypical clinical manifestations

1
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  DOI: 10.1002/alz.13904
  
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<em>Journal of Neuroendocrinology</em> | BSN Journal | Wiley Online Library

1
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  DOI: 10.1111/jne.13415
  
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TRIM46 is not required for axon specification or axon initial segment formation in vivo

1
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  RRID:AB_10063408
  
  DOI: 10.1101/2024.05.23.595556
  
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The Neurog2-Tbr2 axis forms a continuous transition to the neurogenic gene expression state in neural stem cells

1
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  DOI: 10.1016/j.devcel.2024.04.019
  
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Olfactory neuroblastoma mimics molecular heterogeneity and lineage trajectories of small-cell lung cancer

1
1. scibot 24 May 2024
  
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52.53.155.43 52.53.155.43

Effect of M694V mutation in the MEFV gene, associated with Familial Mediterranean fever, on the morphology of iPSC-derived macrophages

1
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  DOI: 10.20944/preprints202403.1184.v1
  
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Neuron-specific RNA-sequencing reveals different responses in peripheral neurons after nerve injury

1
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Srcap haploinsufficiency induced autistic-like behaviors in mice through disruption of Satb2 expression

1
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  DOI: 10.1016/j.celrep.2024.114231
  
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Perivascular neurons instruct 3D vascular lattice formation via neurovascular contact

1
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Effective cryopreservation of human brain tissue and neural organoids

1
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  DOI: 10.1016/j.crmeth.2024.100777
  
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Generation of a healthy heavy smoker patient-derived induced pluripotent stem cell line UHOMi007-A from peripheral blood mononuclear cells

1
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The anti-leprosy drug clofazimine reduces polyQ toxicity through activation of PPARγ

1
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Upregulated GIRK2 counteracts ethanol-induced changes in excitability & respiration in human neurons

1
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  DOI: 10.1523/JNEUROSCI.0918-23.2024
  
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Apr 2024
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Detection of ER Stress in iPSC-Derived Neurons Carrying the p.N370S Mutation in the GBA1 Gene

1
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  DOI: 10.3390/biomedicines12040744
  
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Bacterial symbionts in oral niche use type VI secretion nanomachinery for fitness increase against pathobionts

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Cnicin promotes functional nerve regeneration

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  DOI: 10.1016/j.phymed.2024.155641
  
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Osteopontin drives neuroinflammation and cell loss in MAPT-N279K frontotemporal dementia patient neurons

1
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Patient-derived tumor-like cell clusters for personalized chemo- and immunotherapies in non-small cell lung cancer

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“Heterogeneous subpopulations of GABAAR-responding neurons coexist across neuronal networks scales and developmental stages in health and disease”

1
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Generation of a pluripotent stem cell line (UMGi270-A) and a corresponding CRISPR/Cas9 modified isogenic control (UMGi270-A-1) from a patient with sudden onset dilated cardiomyopathy harboring a FLNC p.R2187P mutation

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BAI1 localizes AMPA receptors at the cochlear afferent post-synaptic density and is essential for hearing

1
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  DOI: 10.1016/j.celrep.2024.114025
  
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Mar 2024
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JNEUROSCI.2031-23.2024.full-html.html

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  DOI: 10.1523/jneurosci.2031-23.2024
  
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Neural and metabolic dysregulation in PMM2-deficient human in vitro neural models

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  DOI: 10.1016/j.celrep.2024.113883
  
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Amino acid formula induces microbiota dysbiosis and depressive-like behavior in mice

1
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Modeling the precise interaction of glioblastoma with human brain region-specific organoids

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Establishment of induced pluripotent stem cell lines derived from Parkinson’s disease Mexican patients: A sporadic (UNAMi002-A) and a familial (UNAMi003-A) case carrying a mutation in PINK1

1
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Generation and Characterization of a Human-Derived and Induced Pluripotent Stem Cell (iPSC) Line from an Alzheimer’s Disease Patient with Neuropsychiatric Symptoms

1
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The soil emergence-related transcription factor PIF3 controls root penetration by interacting with the receptor kinase FER

1
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SOX2 and SOX9 Expression in Developing Postnatal Opossum (Monodelphis domestica) Cortex

1
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Nucleoporin Seh1 controls murine neocortical development via transcriptional repression of p21 in neural stem cells

1
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Protocol for the isolation and culture of microglia, astrocytes, and neurons from the same mouse brain

1
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Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma

1
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Generation of an RBM20-mutation-associated left-ventricular non-compaction cardiomyopathy iPSC line (UMGi255-A) into a DCM genetic background to investigate monogenetic cardiomyopathies

1
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Hexamethylene amiloride synergizes with venetoclax to induce lysosome-dependent cell death in acute myeloid leukemia

1
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Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia

1
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Mof plays distinct roles in hepatic lipid metabolism under healthy or non-alcoholic fatty liver conditions

1
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Biotin rescues manganese-induced Parkinson’s disease phenotypes and neurotoxicity

1
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Lipid metabolism analysis providing insights into nonylphenol multi-toxicity mechanism

1
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PTIR1 acts as an isoform of DDX58 and promotes tumor immune resistance through activation of UCHL5

1
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FBXO38 mediates FGL1 ubiquitination and degradation to enhance cancer immunity and suppress inflammation

1
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Generation of a CRISPR/Cas9-edited Plakoglobin (JUP)knock-out (JMUi001-A-4) iPSC line to model the cardiac phenotype of arrhythmogenic cardiomyopathy

1
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Generation of the induced pluripotent stem cell line ESi108-A from a familial atrial fibrillation patient

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Antibody-directed extracellular proximity biotinylation reveals that Contactin-1 regulates axo-axonic innervation of axon initial segments

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  DOI: 10.1038/s41467-023-42273-8
  
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Small leucine-rich proteoglycans inhibit CNS regeneration by modifying the structural and mechanical properties of the lesion environment

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  DOI: 10.1038/s41467-023-42339-7
  
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Chromatin-modifying enzymes as modulators of nuclear size during lineage differentiation

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  DOI: 10.1038/s41420-023-01639-z
  
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Inhibition of microtubule detyrosination by parthenolide facilitates functional CNS axon regeneration

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  DOI: 10.7554/eLife.88279
  
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Linear ubiquitination at damaged lysosomes induces local NF-κB activation and controls cell survival

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Very-long-chain fatty acids are crucial to neuronal polarity by providing sphingolipids to lipid rafts

1
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Cryo-EM structure of the KLHL22 E3 ligase bound to an oligomeric metabolic enzyme

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cell.com/structure/fulltext/S0969-2126(23)00325-8
Sep 2023
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Establishment of induced pluripotent stem cells IRMBi005-A from a patient with sporadic Alzheimer’s disease

1
1. scibot 30 Sep 2023
  
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  RRID:AB 2,313,773
  
  DOI: 10.1016/j.scr.2023.103216
  
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Palbociclib releases the latent differentiation capacity of neuroblastoma cells

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  DOI: 10.1016/j.devcel.2023.08.028
  
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Establishment of heterozygous and homozygous SHANK3 knockout clonal pluripotent stem cells from the parental hESC line SA001 using CRISPR/Cas9

1
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  DOI: 10.1016/j.scr.2023.103209
  
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Generating high-fidelity cochlear organoids from human pluripotent stem cells

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  DOI: 10.1016/j.stem.2023.06.006
  
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Expression of hyperpolarization-activated current (Ih) in zonally-defined vestibular calyx terminals of the crista

2
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  DOI: 10.1152/jn.00135.2023
  
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Expression of hyperpolarization-activated current (Ih) in zonally defined vestibular calyx terminals of the crista

2
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journals.physiology.org/doi/10.1152/jn.00135.2023
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Lethal adulthood myelin breakdown by oligodendrocyte-specific Ddx54 knockout

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Spatially Distinct Otic Mesenchyme Cells show Molecular and Functional Heterogeneity Patterns Before Hearing Onset

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Analysis of autophagy deficiency and cytotoxicity in autophagy-deficient human embryonic stem cell-derived neurons

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Pou3f1 orchestrates a gene regulatory network controlling contralateral retinogeniculate projections

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  DOI: 10.1016/j.celrep.2023.112985
  
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PIEZO2 in somatosensory neurons controls gastrointestinal transit

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  DOI: 10.1016/j.cell.2023.07.006
  
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Repeated mild traumatic brain injury triggers pathology in asymptomatic C9ORF72 transgenic mice

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  DOI: 10.1093/brain/awad264
  
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Fidgetin interacting with microtubule end binding protein EB3 affects axonal regrowth in spinal cord injury

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Selective deletion of zinc transporter 3 in amacrine cells promotes retinal ganglion cell survival and optic nerve regeneration after injury

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Generation of gene corrected human isogenic iPSC lines (IDVi003-A_CR13, IDVi003-A_CR21, IDVi003-A_CR24) from an inherited retinal dystrophy patient-derived IPSC line ITM2B-5286-3 (IDVi003-A) carrying the ITM2B c.782A > C variant using CRISPR/Cas9

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On salt stress, PLETHORA signaling maintains root meristems

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Customization of the translational complex regulates mRNA-specific translation to control CNS regeneration

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Organ function is preserved despite reorganization of niche architecture in the hair follicle

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Combining a Tetracycline (Tet)-inducible gRNA system and CRISPRa for titratable and timely controlled enhancement of endogenous SHISA3 activation in human induced pluripotent stem cells (hiPSC)

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BPS Publications

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Shedding light on human olfaction: Electrophysiological recordings from sensory neurons in acute slices of olfactory epithelium

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Wfs1E864K knock-in mice illuminate the fundamental role of Wfs1 in endocochlear potential production

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Increased G3BP2-Tau interaction in tauopathies is a natural defense against Tau aggregation

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Organ of Corti explants direct tonotopically graded morphology of spiral ganglion neurons in vitro

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1. scibot 28 Jun 2023
  
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Histone H3 lysine 27 crotonylation mediates gene transcriptional repression in chromatin

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CRISPR/Cas9-mediated generation of human embryonic stem cell sub-lines with HPRT1 gene knockout to model Lesch Nyhan disease

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Generation of three induced pluripotent stem cell lines (RAUi001-A, RAUi001-B and RAUi001-C) from peripheral blood mononuclear cells of a healthy Armenian individual

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Advanced human iPSC-based preclinical model for Parkinson’s disease with optogenetic alpha-synuclein aggregation

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