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miR-181d coordinates homologous recombination and anti-tumor immune responses in glioblastoma

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NAD+ hydrolysis catalyzed by SelO is required for mitochondrial homeostasis

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ID3 deficiency alters chromatin accessibility at DSB sites and enhances vulnerability to HDAC inhibition

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  DOI: 10.1002/ijc.70400
  
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Mar 2026
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THC and CBD Induce Heme Oxygenase-1-Dependent Cell Death and Trigger Mitochondrial Dysfunction in Human Melanoma and Cutaneous Squamous Cell Carcinoma Cells

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Prenatal and postnatal atrazine-induced endocrine and ovarian chemical biotransformation protein disruption in offspring

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XPO1R749Q Mutations Co-occur with POLE Mutations in Cancer and can be Targeted to Overcome Chemoresistance

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An atom-edged magnetic nanomotor for cancer mechanotherapy

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Targeting microbiota-generated acetaldehyde to prevent progression of metabolic dysfunction-associated steatotic liver disease

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Nanoluciferase-CD63 labeling reveals extracellular vesicle kinetics in a mouse intraductal model of ductal carcinoma in situ

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CPSF73 activation and 3′ RNA polymerase II pausing are lost during readthrough transcription after heat shock

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Ribonuclease κ promotes longevity by preventing age-associated accumulation of circular RNA in stress granules

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Intratumoral bacterium Enterocloster bolteae promotes hepatocellular carcinoma progression by directly binding tumor cells

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s10571-026-01695-w_reference-html.html

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IFNγ-induced memory in human macrophages is sustained by the durability of cytokine signaling itself

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Reversible dissociation of mitochondrial Complex V balances anabolic and energy-generating needs in cancer

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Structural and mechanistic analysis of covalent ligands targeting the RNA-binding protein NONO

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Insolubilome profiling defines molecular features that influence protein insolubility with aging

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Local heterochromatin enrichment promotes telomere clustering and PML nuclear body assembly at telomeres

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Small-molecule enhancement of METTL3 S-palmitoylation as a therapeutic strategy for osteoarthritis

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ADT-030, a novel PDE10 inhibitor, demonstrates potent antitumor activity in pancreatic ductal adenocarcinoma

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Integrative CRISPR Screening and RNA Analyses Discover an Essential Role for PUF60 Interactions with 3' Splice Sites in Cancer Progression

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1-s2.0-S2589004226004293-main-html.html

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Extracellular matrix sensing regulates intratumoral heterogeneity of autophagic flux

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The Histone Methyltransferase KMT2D is a Critical Mediator of Lineage Plasticity and Therapeutic Response in Castration Resistant Prostate Cancer

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Dynamic assessment of the allocation of copper to cytochrome c oxidase using size-exclusion chromatography (SEC) combined with inductively coupled plasma mass spectrometry (ICP-MS)

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1-s2.0-S2589004226003718-main-html.html

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Hypoxia restores the acidosis-induced inhibition of cancer cell dissemination

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NF-κB and STAT3 signaling uniquely stratify survival in female glioblastoma patients

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Noncanonical open reading frames from lncRNAs encode functional micropeptides that help shape agronomic traits in rice

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Epigenetic regulation by oleacein mitigates IL-1β-induced inflammation in human SW982 synovial cells

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Targeting and dissociating HIF2α from the molecular chaperone Hsp70 triggers apoptosis in kidney cancer

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1-s2.0-S2589004226003068-main-html.html

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A TRPV4-dependent calcium signaling axis regulates lamellipodial actin architecture to promote cell migration

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Male-biased Yap1-Cd276/B7-H3 axis for immune evasion in medulloblastoma

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IL-6R blockade with tocilizumab disrupts pericyte– and tumor cell–driven IL-6/STAT3 signaling, enhancing docetaxel efficacy in ER+ breast cancer

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Identification of an engram ensemble mediating memory forgetting in the dentate gyrus

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Hippocampal glial alterations are associated with Lamin B1 dysregulation and abnormal nuclear morphology in a rat model of fragile X syndrome

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The mitochondrial intermembrane space nuclease Nuc1 (endonuclease G) prevents mitophagy-mediated mtDNA escape in yeast

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ATP7B-maintained copper stores in myeloid progenitors are required for functional maturation of neutrophils

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Targeting ATR signaling in sarcoma with homologous recombination deficiency

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The Lysine Demethylase KDM4C is an Oncogenic Driver and Regulates ERK Activity in KRAS Mutant Pancreatic Ductal Adenocarcinoma

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Dynamic and differential renal cortical cell-specific mitochondrial metabolism in response to fasting

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Origin of Ewing sarcoma by embryonic reprogramming of neural crest to mesoderm

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Differential contribution of TFE3 isoforms to cell motility and invasion

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Cyclophilin D suppresses colorectal cancer progression through the activation of an autophagy-mediated apoptotic pathway

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Blood-flow restriction resistance training improves skeletal muscle mitochondrial capacity and cardiovascular risk factors in type 2 diabetes

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Mitochondria-targeted antioxidant AntiOxBEN2 prevents metabolic dysfunction-associated steatotic liver disease (MASLD) by enhancing fatty acid oxidation and mitochondrial bioenergetics

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FAM43A coordinates mtDNA replication and mitochondrial biogenesis in response to mtDNA depletion

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Clostridium scindens attenuates acute kidney injury by producing indole-3-acetic acid

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Profiling of Extracellular Vesicles of Non‐Small Cell Lung Cancer Reveals Proteins Associated With Osimertinib Resistance

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e013832.full-html.html

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Melatonin and agomelatine alleviate ivermectin-induced mouse spermatogonia apoptosis via suppression of oxidative stress and calcium overload

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Cell-type resolved protein atlas of brain lysosomes identifies SLC45A1-associated disease as a lysosomal disorder

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Reactive oligodendrocytes promote glioblastoma progression through CCL5/CCR5-mediated glioma stem cell maintenance

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Mitotic chromatin compaction tethers extrachromosomal DNA to chromosomes and prevents their mis-segregation into micronuclei

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1-s2.0-S258900422600129X-main-html.html

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Immune gene diversity and STING1 variants in shaping cancer immunity across different genetic ancestry populations

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Uncovering genetic interactions in the DNA repair network in response to endogenous damage and ionizing radiation

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Glycolysis inhibition functionally reprograms T follicular helper cells and reverses lupus

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Optimized selection of specific antibodies against rodent ESR1 proteins and their application for immunohistochemistry and dual immunohistofluorescence with the specific anti-ESR2 antibody PPZ0506

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NF1 Loss Remodels Tumor Niches for Immune Evasion

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Microenvironmental TGF-β is an early driver of NF1-associated tumor formation

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HBx hijacks the miR-19a-3p/BAMBI/TGF-β1 axis to impair the anti-tumour activity of CD4+ T cells in diffuse large B-cell lymphoma

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Reverse molecular pharmacology identifies the non-canonical axis of IRAK as a chemoresistance factor in neuroblastoma

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The ionotropic AMPA receptor contributes to autoimmunity via altered regulatory T cell differentiation

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Structure of the lysosomal KICSTOR-GATOR1-SAMTOR nutrient-sensing supercomplex

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In vivo detection of immune responses via cytokine activity labeling

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Aberrant nuclear pore complex degradation contributes to neurodegeneration in VCP disease

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RNA-coupled CRISPR screens reveal ZNF207 as a regulator of LMNA aberrant splicing in progeria

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1-s2.0-S2589004225028019-main-html.html

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FOCAS: Transcriptome-wide screening of individual m6A sites functionally dissects epitranscriptomic control of gene expression in cancer

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Extracellular GPX4 impairs antitumor immunity via dendritic ZP3 receptors

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Downregulation of ZBTB7A/LRF increases fetal hemoglobin expression in β0-thalassemia/hemoglobin E erythroid cells

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Pharmacologic reversal of advanced Alzheimer’s disease in mice and identification of potential therapeutic nodes in human brain

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Mitochondrial VHL rewires cell metabolism in hypoxia

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Hepatic adaptation to chronic metabolic stress primes tumorigenesis

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RAS mutation–specific responses to paralog- and state-selective RAS inhibitors

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Degradation of LMO2 in T cell leukaemia results in collateral breakdown of transcription complex partners and causes LMO2-dependent apoptosis

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Structure of the TXNL1-bound proteasome

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Distinct components of mRNA vaccines cooperate to instruct efficient germinal center responses

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FEBS Press

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CDK4/6 inhibition reprograms the breast cancer immunopeptidome via Rb-dependent chromatin and transcriptomic remodeling

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The exit of naive pluripotency contains a metabolism-induced checkpoint for telomere homeostasis

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Post-transcriptional control of HIF-1α by MBNL1 restrains hypoxia-driven stemness in GBM

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Deep learning reveals endogenous sterols as allosteric modulators of the GPCR–Gα interface

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Sensitized mast cells for targeted drug delivery and augmented cancer immunotherapy

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SIRT2 regulates the SMARCB1 loss-driven differentiation block in ATRT

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APLP1 Interacts with SARM1 and Regulates Axonal Maintenance and Post-Injury Degeneration

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Interleukin-1/Toll-like receptor signaling potentiates macrophage olfactory receptor 2-driven atherosclerosis

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Cadherin-1-mediated communication at the leader-follower boundary controls mouse breast tumor organoid collective migration

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Biased histamine signaling selectively gates fat preference

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Harnessing the E3 ligase SPOP for targeted degradation of the NUP98::KDM5A fusion oncoprotein

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Identification of a common ketohexokinase-dependent link driving alcohol intake and alcohol-associated liver disease in mice

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C5aR1+ microglia exacerbate neuroinflammation and cerebral edema in acute brain injury

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UMP functions as an endogenous regulator of NR4A1 to control gastric cancer progression

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Herpes simplex virus type 1 disseminates from the cornea to the CNS in mice by thwarting type III interferon immune defenses

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MIAT-DHX9 spatiotemporal expression drives venous neointimal hyperplasia through nucleolar homeostasis and mitotic progression

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Repurposing Nelfinavir: AIM2 Inflammasome-Driven Anti-tumor Effects in Glioblastoma

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Control of aging-associated neurodegeneration via hypothalamic extracellular vesicles containing parathymosin

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Non-orthosteric inhibition of enolase 1 impedes growth of triple-negative breast cancer

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The pan-cancer mutational landscape of MLL3 and its impact on prognosis and immunochemotherapy

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Feedforward miR-181d degradation modulates population variance of methyl-guanine methyl transferase and temozolomide resistance

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Intracellular Interleukin-1α in Peritumoral Monocytes Induces IL8 Production and Inhibits Mitophagy to Promote Stemness and Metastasis of Hepatocellular Carcinoma

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Polychlorinated Biphenyls Alter Estrogen Receptor β-mediated Epigenetic Regulation, Promoting Endometriosis

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Selective Enhancer Dependencies in MYC-Intact and MYC-Rearranged Germinal Center B-cell Diffuse Large B-cell Lymphoma

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Mesothelin as a biomarker and potential therapeutic target in rheumatoid arthritis bone destruction

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L-asparaginase treatment induces a tumor metabolic plasticity and reveals a vulnerability to PARP1/2 inhibitor Olaparib, in B-cell lymphomas

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Accumulation of succinate suppresses de novo purine synthesis through succinylation-mediated control of the mitochondrial folate cycle

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Nuclear hormone-sensitive lipase regulates adipose tissue mass and adipocyte metabolism

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RAF-independent MEK mutations drive refractory histiocytic neoplasms but respond to ERK inhibition

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Modeling response to the KRAS-G12C inhibitor AZD4625 in KRASG12C NSCLC patient-derived xenografts reveals insights into primary resistance mechanisms

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Nuclear U1 snRNA facilitates the dimerization of hnRNPA2B1 to enhance anti-DNA viral innate immunity

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Microglial NLRP3 inflammasome activation leads to perineuronal net loss in cocultured neurons

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A non-canonical immunometabolic function of BRD3 during sepsis

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Senataxin promotes recombination fidelity during antigen receptor gene diversification

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Inflammasome-independent IL-1β activation via staphopain A protease of Staphylococcus aureus[image]

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Germline-somatic liaison dictates cancer subtype via de novo steroid biosynthesis

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Lipid peroxidation and type I interferon coupling fuels pathogenic macrophage activation causing tuberculosis susceptibility

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CRISPR-Cas9 screening reveals G2E3 as a novel ubiquitin-linked factor controlling autophagosome-lysosome fusion and cancer cell progression

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Machine-learning-guided discovery of SLC25A45 as a mediator of mitochondrial methylated amino acid import and carnitine synthesis

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Parkin Induces Ubiquitination and Large Extracellular Vesicle Release of HMGB1 to Activate Antitumor Immunity

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Lipid-regulated phosphorylation hierarchy of the T cell receptor tyrosine motifs

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hsu-et-al-2025-phosphoproteomics-of-osimertinib-tolerant-persister-cells-reveals-targetable-kinase-substrate-signatures-html.html

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Dual molecular therapy targeting tumor cell heterogeneity improves therapeutic efficacy in glioblastoma

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USP9X is a mechanosensitive deubiquitinase that controls tumor cell invasiveness and drug response through YAP stabilization

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Liver-breast communication of adipocyte-oriented exosomes drives primary mammary cancer progression

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Neuropeptide adrenomedullin remodels stemness and macrophage dynamics in glioblastoma

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Control of Inflammatory Response by Tissue Microenvironment

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Stable isotope tracer captures the anabolic response of human skeletal muscle microtissues undetected by puromycin labeling

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Protocol for isolating and characterizing extracellular vesicles by ultracentrifugation from bone marrow-derived macrophages

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FLT3L-based drug conjugate effectively targets chemoresistant leukemia stem cells in acute myeloid leukemia

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Spirodelae Herba ethanol extract attenuates neurotoxicity in hippocampal cells and improves scopolamine-induced cognitive impairment in mice

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UBE2T-mediated HP1α ubiquitination enhances nucleolar function and promotes the progression of IDH1/TP53-mutant glioma

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Cetuximab increases LGR5 expression and augments LGR5-targeting antibody-drug conjugate efficacy in patient-derived colorectal cancer models

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MiR-34a deficiency enhances nucleic acid sensing and type I IFN signaling in a mouse model of Alzheimer’s disease

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2025.09.04.674332v2.full-html.html

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Spatiotemporal differential regulation of extrasynaptic GluN2B receptor subunits and PSA-NCAM in brain aging and Alzheimer’s disease

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Cardiac sodium-glucose co-transporter 1 (SGLT1) contributes to heart failure in a mouse model of diabetic cardiomyopathy

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The hexosamine biosynthetic pathway drives tumor immune evasion via translational control of PD-L1 at the elongation level

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Environmental and genetic risk factors of depression converge on neuronal dysfunction driven by changes in cholesterol homeostasis

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A pathological role of O-GlcNAcylation-driven TR11B production and function in lung adenocarcinoma

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Coordination of autophagosome closure and release by the Alzheimer’s disease-associated protein BIN1

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TELS1 stabilizes t-loops independently of TRF2 and controls telomere length in pluripotent cells

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Human papillomavirus integration induces oncogenic host gene fusions in oropharyngeal cancers

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Novel Metastasis Suppressor PI3KC2β Is Mediated by mTORC1 Signaling in Breast Cancer

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A Hotspot Phosphorylation Site on SHP2 Drives Oncoprotein Activation and Drug Resistance

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Conversion of natural cytokine receptors into orthogonal synthetic biosensors

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2025.08.22.671484v1.full-html.html

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Polyserine-mediated targeting of FAF2/UBXD8 ameliorates tau aggregation

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Coxsackievirus B infection invokes unique cell-type-specific responses in primary human pancreatic islets

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Uncovering phenotypic inheritance from single cells with Microcolony-seq

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Long-range deployment of tumor-antigen-specific cytotoxic T lymphocytes inhibits lung metastasis of breast cancer

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BACH2 promotes seeding and establishment of long-lived HIV-1 reservoir in memory CD4+ T cells

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Design of multi-target peptide modulators for protein chaperone networks

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Cryo-EM structure of a cell-free synthesized full-length human β1-adrenergic receptor in complex with Gs

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A redox switch in p21-CDK feedback during G2 phase controls the proliferation-cell cycle exit decision

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Integrative genomic identification of therapeutic targets for pancreatic cancer

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Ridaifen derivatives function as potent lysosomotropic agents, depending on their basic side chains.

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A brain‐derived tau oligomer polymorph is associated with cognitive resilience to Alzheimer's disease

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BPS Publications

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tran-et-al-2025-mechanism-of-shear-stress-induced-atp-release-in-ventricular-myocytes-roles-of-pannexin-and-mitochondria-html.html

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ER-phagy and proteostasis defects prime pancreatic epithelial state changes in KRAS-mediated oncogenesis

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Heparan Sulfate Proteoglycans as Potential Markers for In Vitro Human Neural Lineage Specification

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Autophagy suppresses the formation of hepatocyte-derived cancer-initiating ductular progenitor cells in the liver

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Redistribution of fragmented mitochondria ensures symmetric organelle partitioning and faithful chromosome segregation in mitotic mouse zygotes

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Distinct specificity and functions of PRC2 subcomplexes in human stem cells and cardiac differentiation

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exoCasMINI: A T5 exonuclease fused CRISPR-Cas12f system with enhanced gene editing efficiency

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Sustained neuronal DNA damage and PARP activation lead to VEGFA-mediated blood-brain barrier disruption in radiation-induced brain injury

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A Hotspot Phosphorylation Site on SHP2 Drives Oncoprotein Activation and Drug Resistance

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Preadipocyte-induced upregulation of IGFBP5 enhances ovarian cancer tumorigenesis via CREB signaling

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Combined MEK and PARP inhibition enhances radiation response in rectal cancer

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Zbtb16 determines the fate plasticity of cardiovascular progenitors through IGF2BP3-mediated mRNA stabilization

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Tumor-resident probiotic Clostridium butyricum improves aPD-1 efficacy in colorectal cancer models by inhibiting IL-6-mediated immunosuppression

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Differential Efficacy of Bevacizumab and Erlotinib in Preclinical Models of Renal Medullary Carcinoma and Fumarate Hydratase–Deficient Renal Cell Carcinoma

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Reconstructed cell-type-specific rhythms in human brain link Alzheimer’s pathology, circadian stress, and ribosomal disruption

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The neurexin gene family regulates olfactory glomerular formation

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Multi-dimensional metabolomic remodeling under diverse muscle atrophic stimuli in vivo

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Glucose-dependent glycosphingolipid biosynthesis fuels CD8+ T cell function and tumor control

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Keratinocyte-derived VEGF-A is an essential pro-migratory autocrine mediator, acting through the KDR/GEF-H1/RhoA pathway

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KRAS-driven pancreatic ductal adenocarcinoma cell lines harbour putative cancer stem cells

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Selective Alanine Transporter Utilization is a Therapeutic Vulnerability in ARID1A-Mutant Ovarian Cancer

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Pentagalloyl glucose inhibits monosodium urate-induced inflammation and NLRP3 inflammasome formation via TAK1 | American Journal of Physiology-Cell Physiology | American Physiological Society

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RNF13 Regulates the Endolysosomal Pathway Through Interaction with the Small GTPase Arl8B

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2025.07.28.667286v1.full-html.html

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2025.07.28.667160v1.full-html.html

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Cargo-selective regulation of clathrin-mediated endocytosis by AMP-activated protein kinase

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Sympathetic innervation maintains the murine quiescent skeletal muscle stem cell pool via perivascular-derived Angpt1

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Ginsenoside 20(S)-Rg3 upregulates SQLE to reprogram cholesterol metabolism of ovarian cancer cells

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BRD9 inhibition overcomes oncolytic virus therapy resistance in glioblastoma

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1-s2.0-S2589004225014907-main-html.html

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PFKFB3 activates CAD to enhance de novo pyrimidine synthesis for cell growth

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Direct transdifferentiation of tumorigenic melanoma cells induces tumor cell reversion

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Retinoic acid-induced 2 deficiency impairs genomic stability in breast cancer

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Distinct adipose progenitor cells emerging with age drive active adipogenesis

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Transfer RNA acetylation regulates in vivo mammalian stress signaling

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Gasdermin C cleavage by Cathepsin S modulates Rab7 vesicles in intestinal epithelial cells to amplify anti-helminth immunity

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