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  1. Last 7 days
  2. www.embopress.org www.embopress.org
    DUSP6 inhibition overcomes neuregulin/HER3-driven therapy tolerance in HER2+ breast cancer
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    1. scibot 18 Jul 2024
      addgene_12251

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  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DUSP6 inhibition overcomes neuregulin/HER3-driven therapy tolerance in HER2+ breast cancer
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    1. scibot 18 Jul 2024
      addgene_12251

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    ncbi.nlm.nih.gov/pmc/articles/PMC11251193/
  4. www.sciencedirect.com www.sciencedirect.com
    Metformin synergizes with gilteritinib in treating FLT3-mutated leukemia via targeting PLK1 signaling
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    1. scibot 17 Jul 2024
      RRID:Addgene_12251

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    sciencedirect.com/science/article/pii/S2666379124003598
  5. Jul 2024
  6. www.cell.com www.cell.com
    SigmaR1 shapes rough endoplasmic reticulum membrane sheets
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    1. scibot 12 Jul 2024
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    cell.com/developmental-cell/abstract/S1534-5807(24)00382-4
  7. www.cell.com www.cell.com
    Genetic ablation of adhesion ligands mitigates rejection of allogeneic cellular immunotherapies
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    1. scibot 11 Jul 2024
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    cell.com/cell-stem-cell/abstract/S1934-5909(24)00219-4
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    High-Throughput Discovery and Characterization of Viral Transcriptional Effectors in Human Cells
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    1. scibot 03 Jul 2024
      Addgene_12251

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    ncbi.nlm.nih.gov/pmc/articles/PMC10350249/
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Generation and characterization of inducible KRAB-dCas9 iPSCs from primates for cross-species CRISPRi
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    1. scibot 01 Jul 2024
      RRID:Addgene_12251

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    ncbi.nlm.nih.gov/pmc/articles/PMC11214527/
  10. Jun 2024
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumour-derived Extracellular Vesicle and Particle Reprogramming of Interstitial Macrophages in the Lung Pre-Metastatic Niche Enhances Vascular Permeability and Metastatic Potential
    1
    1. scibot 21 Jun 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11160910/
  12. www.sciencedirect.com www.sciencedirect.com
    STING orchestrates the neuronal inflammatory stress response in multiple sclerosis
    1
    1. scibot 21 Jun 2024
      RRID:Addgene_12251

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    sciencedirect.com/science/article/pii/S0092867424005762
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The epithelial adherens junction component PLEKHA7 regulates ECM remodeling and cell behavior through miRNA-mediated regulation of MMP1 and LOX
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    1. scibot 20 Jun 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11160653/
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cadherin-11 contributes to the heterogenous and dynamic Wnt-Wnt-β-catenin pathway activation in Ewing sarcoma
    1
    1. scibot 20 Jun 2024
      plasmid_12251

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    ncbi.nlm.nih.gov/pmc/articles/PMC11178195/
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mechanistic patterns and clinical implications of oncogenic tyrosine kinase fusions in human cancers
    1
    1. scibot 20 Jun 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11178778/
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TPX2 overexpression promotes sensitivity to dasatinib in breast cancer by activating YAP transcriptional signaling
    1
    1. scibot 13 Jun 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11161735/
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR-Cas9 editing of synaptic genes in human embryonic stem cells for functional analysis in induced human neurons
    1
    1. scibot 10 Jun 2024
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  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Prickle1‐driven basement membrane deposition of the iPSC‐derived embryoid bodies is separable from the establishment of apicobasal polarity
    1
    1. scibot 09 Jun 2024
      https://www.addgene.org/12251/

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  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BRCA1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote continuous DNA synthesis
    1
    1. scibot 07 Jun 2024
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  20. www.sciencedirect.com www.sciencedirect.com
    The ribotoxic stress response drives UV-mediated cell death
    2
    1. scibot 06 Jun 2024
      Addgene 12251

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      RRID:Addgene_12251

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    sciencedirect.com/science/article/pii/S0092867424005270
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Disease-linked mutations in Munc18-1 deplete synaptic Doc2
    1
    1. scibot 06 Jun 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11146428/
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ATP6AP2, a regulator of LRP6/β-catenin protein trafficking, promotes Wnt/β-catenin signaling and bone formation in a cell type dependent manner
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    1. scibot 03 Jun 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11137048/
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lack of SPNS1 results in accumulation of lysolipids and lysosomal storage disease in mouse models
    1
    1. scibot 03 Jun 2024
      pMDLg/pRRE

      DOI: 10.1172/jci.insight.175462

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  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protocol for preclinical evaluation of locoregionally delivered CAR T cells in patient-derived xenograft models of brain tumors
    1
    1. scibot 03 Jun 2024
      plasmid_12251

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  25. May 2024
  26. journals.asm.org journals.asm.org
    The recruitment of TRiC chaperonin in rotavirus viroplasms correlates with virus replication
    2
    1. scibot 24 May 2024
      RRID:Addgene_12251

      DOI: 10.1128/mbio.00499-24

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      RRID:Addgene_12251

      DOI: 10.1128/mbio.00499-24

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    journals.asm.org/doi/10.1128/mbio.00499-24
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KDM7A-DT induces genotoxic stress, tumorigenesis, and progression of p53 missense mutation-associated invasive breast cancer
    1
    1. scibot 19 May 2024
      pMDLg/pRRE

      DOI: 10.3389/fonc.2024.1227151

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    ncbi.nlm.nih.gov/pmc/articles/PMC11097164/
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR/Cas9 genome editing of CCR5 combined with C46 HIV-1 fusion inhibitor for cellular resistant to R5 and X4 tropic HIV-1
    1
    1. scibot 19 May 2024
      plasmid_12251

      DOI: 10.1038/s41598-024-61626-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC11091187/
  29. link.springer.com link.springer.com
    Sex- and species-specific contribution of CD99 to T cell costimulation during multiple sclerosis
    1
    1. scibot 16 May 2024
      RRID:Addgene_12251

      DOI: 10.1186/s13293-024-00618-y

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    link.springer.com/article/10.1186/s13293-024-00618-y
  30. link.springer.com link.springer.com
    Imaging CAR-NK cells targeted to HER2 ovarian cancer with human sodium-iodide symporter-based positron emission tomography
    1
    1. scibot 15 May 2024
      RRID:Addgene_12251

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  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    New AAV9 engineered variants with enhanced neurotropism and reduced liver off-targeting in mice and marmosets
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  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Hippo kinases control inflammatory Hippo signaling and restrict bacterial infection in phagocytes
    1
    1. scibot 12 May 2024
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  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Prolonged depletion of profilin 1 or F-actin causes an adaptive response in microtubules
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    1. scibot 12 May 2024
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  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cell competition promotes metastatic intestinal cancer through a multistage process
    1
    1. scibot 09 May 2024
      Addgene12251

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    ncbi.nlm.nih.gov/pmc/articles/PMC11068562/
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Method for the Production of Recombinant VSVs with Confirmation of Biological Activity
    1
    1. scibot 05 May 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11062106/
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NFATC2IP is a mediator of SUMO-dependent genome integrity
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    ncbi.nlm.nih.gov/pmc/articles/PMC11065178/
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MILIP Binding to tRNAs Promotes Protein Synthesis to Drive Triple-Negative Breast Cancer
    1
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      DOI: 10.1158/0008-5472.CAN-23-3046

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    ncbi.nlm.nih.gov/pmc/articles/PMC11063688/
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Influenza Virus Reduces Ubiquitin E3 Ligase MARCH10 Expression to Decrease Ciliary Beat Frequency
    1
    1. scibot 02 May 2024
      RRID:Addgene_12251

      DOI: 10.1152/ajplung.00191.2022

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    ncbi.nlm.nih.gov/pmc/articles/PMC10151042/
  39. Apr 2024
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combined SNPs sequencing and allele specific proteomics capture reveal functional causality underpinning the 2p25 prostate cancer susceptibility locus
    1
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      DOI: 10.21203/rs.3.rs-3943095/v1

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    ncbi.nlm.nih.gov/pmc/articles/PMC11030545/
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stepwise Stiffening/Softening of and Cell Recovery from Reversibly Formulated Hydrogel Double Networks
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11030224/
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Temporal coordination of the transcription factor response to H2O2 stress
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    ncbi.nlm.nih.gov/pmc/articles/PMC11039679/
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A disease-associated PPP2R3C-MAP3K1 phospho-regulatory module controls centrosome function
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      DOI: 10.1101/2024.04.02.587836

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    ncbi.nlm.nih.gov/pmc/articles/PMC11014585/
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MHC class I-dressing is mediated via phosphatidylserine recognition and is enhanced by polyI:C
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    ncbi.nlm.nih.gov/pmc/articles/PMC11046299/
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IQGAP3 Is an Important Mediator of Skin Inflammatory Diseases
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    1. scibot 29 Apr 2024
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      DOI: 10.3390/ijms25084545

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    ncbi.nlm.nih.gov/pmc/articles/PMC11050236/
  46. www.sciencedirect.com www.sciencedirect.com
    Exploiting a subtype-specific mitochondrial vulnerability for successful treatment of colorectal peritoneal metastases
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    1. scibot 26 Apr 2024
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    sciencedirect.com/science/article/pii/S2666379124001927
  47. www.sciencedirect.com www.sciencedirect.com
    Functional sensory circuits built from neurons of two species
    2
    1. scibot 26 Apr 2024
      Addgene Cat# 12251

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  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An EBV-related CD4 TCR immunotherapy inhibits tumor growth in an HLA-DP5+ nasopharyngeal cancer mouse model
    1
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      RRE

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  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone H2A variant H2A.B is enriched in transcriptionally active and replicating HSV-1 lytic chromatin
    1
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      pMDLg-pRRE

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  50. www.sciencedirect.com www.sciencedirect.com
    RAD52-dependent mitotic DNA synthesis is required for genome stability in Cyclin E1-overexpressing cells
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    sciencedirect.com/science/article/pii/S2211124724004443
  51. aacrjournals.org aacrjournals.org
    Sarcoma cells secrete hypoxia-modified collagen VI to weaken the lung endothelial barrier and promote metastasis
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    aacrjournals.org/cancerres/article/84/7/977/742043/Sarcoma-Cells-Secrete-Hypoxia-Modified-Collagen-VI
  52. aacrjournals.org aacrjournals.org
    Hypoxia-responsive CAR-T cells exhibit reduced exhaustion and enhanced efficacy in solid tumors
    1
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  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Detecting subtle transcriptomic perturbations induced by lncRNAs knock-down in single-cell CRISPRi screening using a new sparse supervised autoencoder neural network
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  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Insulin signalling regulates Pink1 mRNA localization via modulation of AMPK activity to support PINK1 function in neurons
    1
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      pMDLg/pRRE

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  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: Circular RNA as a source of neoantigens for cancer vaccines
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  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting of vulnerabilities of drug-tolerant persisters identified through functional genetics delays tumor relapse
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  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mesenchymal glioma stem cells trigger vasectasia—distinct neovascularization process stimulated by extracellular vesicles carrying EGFR
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  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrated proteomics reveals autophagy landscape and an autophagy receptor controlling PKA-RI complex homeostasis in neurons
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  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FcRn regulates antigen presentation in dendritic cells downstream of DEC205-targeted vaccines
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  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The recruitment of TRiC chaperonin in rotavirus viroplasms correlates with virus replication
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  61. www.sciencedirect.com www.sciencedirect.com
    Human iPSC 4R tauopathy model uncovers modifiers of tau propagation
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  62. Mar 2024
  63. www.sciencedirect.com www.sciencedirect.com
    Endocytic activation and exosomal secretion of matriptase stimulate the second wave of EGF signaling to promote skin and breast cancer invasion
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  64. www.sciencedirect.com www.sciencedirect.com
    A gut-derived hormone regulates cholesterol metabolism
    2
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      RRID:Addgene_12251

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  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NOTUM-MEDIATED WNT SILENCING DRIVES EXTRAVILLOUS TROPHOBLAST CELL LINEAGE DEVELOPMENT
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  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An engineered biosensor enables dynamic aspartate measurements in living cells
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  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel meriolin derivatives activate the mitochondrial apoptosis pathway in the presence of antiapoptotic Bcl-2
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  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The ubiquitin ligase HUWE1 enhances WNT signaling by antagonizing destruction complex-mediated β-catenin degradation and through a mechanism independent of β-catenin stability
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  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR/Cas9 model of prostate cancer identifies Kmt2c deficiency as a metastatic driver by Odam/Cabs1 gene cluster expression
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  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel Estrogen Receptor Dimerization BRET-Based Biosensors for Screening Estrogenic Endocrine-Disrupting Chemicals
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  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Roflumilast inhibits tumor growth and migration in STK11/LKB1 deficient pancreatic cancer
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      plasmid_12251

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  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FH variant pathogenicity promotes purine salvage pathway dependence in kidney cancer
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  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    scAbsolute: measuring single-cell ploidy and replication status
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  74. www.sciencedirect.com www.sciencedirect.com
    Effectiveness of chemical inactivation of infectious liquid biological waste: a randomized sample study of research laboratories in Switzerland
    3
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  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Disease-associated polyalanine expansion mutations impair UBA6-dependent ubiquitination
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      pMDLg/pRRE

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  76. Feb 2024
  77. www.sciencedirect.com www.sciencedirect.com
    A di-acetyl-decorated chromatin signature couples liquid condensation to suppress DNA end synapsis
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      AddgeneCat#12251

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    The proteomic landscape of genotoxic stress-induced micronuclei
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  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis for antibody recognition of the proximal MUC16 ectodomain
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      pMDLg/pRRE

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  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epigenomic analyses identify FOXM1 as a key regulator of anti-tumor immune response in esophageal adenocarcinoma
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  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Production of infectious reporter murine norovirus by VP2 trans-complementation
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      pMDLg/pRRE HIV-1

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  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 and oncolytic EV-D68-encoded proteases differentially regulate pyroptosis
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  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The exocyst complex and intracellular vesicles mediate soluble protein trafficking to the primary cilium
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  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Engineering an Autonucleolytic Mammalian Suspension Host Cell Line to Reduce DNA Impurity Levels in Serum-Free Lentiviral Process Streams
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  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Agent-based modeling of the prostate tumor microenvironment uncovers spatial tumor growth constraints and immunomodulatory properties
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  86. link.springer.com link.springer.com
    Endothelial lipase variant T111I does not alter inhibition by angiopoietin-like proteins
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    Combined therapy of CAR-IL-15/IL-15Rα-T cells and GLIPR1 knockdown in cancer cells enhanced anti-tumor effect against gastric cancer
    1
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      pMDLg/pRRE

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  88. www.sciencedirect.com www.sciencedirect.com
    Stem-like progenitor and terminally differentiated TFH-like CD4+ T cell exhaustion in the tumor microenvironment
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  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hyaluronic acid turnover controls the severity of cerebral cavernous malformations in bioengineered human micro-vessels
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  90. www.biorxiv.org www.biorxiv.org
    PTPRZ1-targeting RNA CAR-T cells exert antigen-specific and bystander antitumor activity in glioblastoma
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  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sequential CRISPR screening reveals partial NatB inhibition as a strategy to mitigate alpha-synuclein levels in human neurons
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    1. scibot 15 Feb 2024
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  92. cancerci.biomedcentral.com cancerci.biomedcentral.com
    NY-ESO-1-specific T cell receptor-engineered T cells and Tranilast, a TRPV2 antagonist bivalent treatment enhances the killing of esophageal cancer: a dual-targeted cancer therapeutic route
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  93. www.sciencedirect.com www.sciencedirect.com
    Retrospective identification of cell-intrinsic factors that mark pluripotency potential in rare somatic cells
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  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Actin-dependent recruitment of AGO2 to the zonula adherens
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  95. journals.plos.org journals.plos.org
    CRISPR screen for protein inclusion formation uncovers a role for SRRD in the regulation of intermediate filament dynamics and aggresome assembly
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  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting the SphK1/S1P/PFKFB3 axis suppresses hepatocellular carcinoma progression by disrupting glycolytic energy supply that drives tumor angiogenesis
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      pMDLg/pRRE

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  97. www.sciencedirect.com www.sciencedirect.com
    Pharmacological inhibition of neddylation impairs long interspersed element 1 retrotransposition
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  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A synthetic agent ameliorates polycystic kidney disease by promoting apoptosis of cystic cells through increased oxidative stress
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  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    K-Ras(V12) differentially affects the three Akt isoforms in lung and pancreatic carcinoma cells and upregulates E-cadherin and NCAM via Akt3
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  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Obesity causes mitochondrial fragmentation and dysfunction in white adipocytes due to RalA activation
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  101. Jan 2024
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RBL2 represses the transcriptional activity of Multicilin to inhibit multiciliogenesis
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  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PICH deficiency limits the progression of MYC-induced B-cell lymphoma
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  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Isolation and Characterization of Neutralizing Monoclonal Antibodies from a Large Panel of Murine Antibodies against RBD of the SARS-CoV-2 Spike Protein
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  105. www.sciencedirect.com www.sciencedirect.com
    EXO1 protects BRCA1-deficient cells against toxic DNA lesions
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  106. link.springer.com link.springer.com
    Selective gene expression maintains human tRNA anticodon pools during differentiation
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  107. www.sciencedirect.com www.sciencedirect.com
    PAPAS promotes differentiation of mammary epithelial cells and suppresses breast carcinogenesis
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  108. Dec 2023
  109. www.sciencedirect.com www.sciencedirect.com
    FEZ1 participates in human embryonic brain development by modulating neuronal progenitor subpopulation specification and migration
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    1. scibot 21 Dec 2023
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  110. www.sciencedirect.com www.sciencedirect.com
    The MHC-E peptide ligands for checkpoint CD94/NKG2A are governed by inflammatory signals, whereas LILRB1/2 receptors are peptide indifferent
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      Addgene Cat: 12251

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  111. www.sciencedirect.com www.sciencedirect.com
    KDM5B predicts temozolomide-resistant subclones in glioblastoma
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  112. link.springer.com link.springer.com
    Rational optimization of a transcription factor activation domain inhibitor
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  113. Nov 2023
  114. www.sciencedirect.com www.sciencedirect.com
    Copine-6 is a Ca2+ sensor for activity-induced AMPA receptor exocytosis
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      Plasmid_12251

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  115. www.sciencedirect.com www.sciencedirect.com
    An integrated in vitro human iPSCs-derived neuron and in vivo animal approach for preclinical screening of anti-seizure compounds
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  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Optimized peptide nanofibrils as efficient transduction enhancers for in vitro and ex vivo gene transfer
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  117. www.sciencedirect.com www.sciencedirect.com
    CRISPR/Cas9 screens unravel miR-3689a-3p regulating sorafenib resistance in hepatocellular carcinoma via suppressing CCS/SOD1-dependent mitochondrial oxidative stress
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    sciencedirect.com/science/article/pii/S1368764623000985
  118. Oct 2023
  119. www.sciencedirect.com www.sciencedirect.com
    Regulation of STING activity in DNA sensing by ISG15 modification
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  120. www.sciencedirect.com www.sciencedirect.com
    Sequential activation of E2F via Rb degradation and c-Myc drives resistance to CDK4/6 inhibitors in breast cancer
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  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preclinical development of a chimeric antigen receptor T cell therapy targeting FGFR4 in rhabdomyosarcoma
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  122. www.nature.com www.nature.com
    Chromatin-modifying enzymes as modulators of nuclear size during lineage differentiation
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  123. Sep 2023
  124. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Insights into product and process related challenges of lentiviral vector bioprocessing
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  125. www.sciencedirect.com www.sciencedirect.com
    Mechanosensitive accumulation of non-muscle myosin IIB during mitosis requires its translocation activity
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  126. 52.53.155.43 52.53.155.43
    vdad120-html.html
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  127. www.biorxiv.org www.biorxiv.org
    TPX2 expression promotes sensitivity to dasatinib in breast cancer by activating the YAP transcriptional signaling
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  128. Aug 2023
  129. www.sciencedirect.com www.sciencedirect.com
    Multiple genes in a single GWAS risk locus synergistically mediate aberrant synaptic development and function in human neurons
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  130. www.biorxiv.org www.biorxiv.org
    Endothelial Lipase Variant, T111I, Does Not Alter Inhibition by Angiopoietin-like Proteins
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  131. www.nature.com www.nature.com
    Efficient generation of functional neurons from mouse embryonic stem cells via neurogenin-2 expression
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  132. www.sciencedirect.com www.sciencedirect.com
    IL-2 can signal via chemokine receptors to promote regulatory T cells’ suppressive function
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  133. 52.53.155.43 52.53.155.43
    Membrane-localized neoantigens predict the efficacy of cancer immunotherapy
    3
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  134. Jul 2023
  135. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Early protective effect of a (“pan”) coronavirus vaccine (PanCoVac) in Roborovski dwarf hamsters after single-low dose intranasal administration
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  136. www.sciencedirect.com www.sciencedirect.com
    Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy
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  137. www.sciencedirect.com www.sciencedirect.com
    Parallel CRISPR-Cas9 screens identify mechanisms of PLIN2 and lipid droplet regulation
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  138. 52.53.155.43 52.53.155.43
    Copine-6 is a Ca2+ sensor for activity-induced AMPA receptor exocytosis
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    1. scibot 16 Jul 2023
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  139. pubs.acs.org pubs.acs.org
    SIRIUS, Ultra-Scintillating Upconversion Breast Implant for Remote Orthotopic Photodynamic Therapy
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      DOI: 10.1021/acsnano.3c01916

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  140. 52.53.155.43 52.53.155.43
    cir-22-0815-html.html
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  141. Jun 2023
  142. www.sciencedirect.com www.sciencedirect.com
    Microbiota-produced indole metabolites disrupt mitochondrial function and inhibit Cryptosporidium parvum growth
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    1. scibot 29 Jun 2023
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  143. www.sciencedirect.com www.sciencedirect.com
    QKI shuttles internal m7G-modified transcripts into stress granules and modulates mRNA metabolism
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  144. www.sciencedirect.com www.sciencedirect.com
    FIRRM/C1orf112 is synthetic lethal with PICH and mediates RAD51 dynamics
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  145. www.biorxiv.org www.biorxiv.org
    Transcriptional landscape of DTP-DTEP transition reveals DUSP6 as a driver of HER2 inhibitor tolerance via Neuregulin/HER3 axis
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  146. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CDT1 inhibits CMG helicase in early S phase to separate origin licensing from DNA synthesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC7614657/
  147. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SLIT2/ROBO1 signaling suppresses mTORC1 for organelle control and bacterial killing
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  148. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Disruption of the gut microbiota confers cisplatin resistance in epithelial ovarian cancer
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  149. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IKKβ primes inflammasome formation by recruiting NLRP3 to the trans-Golgi network
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  150. May 2023
  151. www.embopress.org www.embopress.org
    Presynaptic targeting of botulinum neurotoxin type A requires a tripartite PSG-Syt1-SV2 plasma membrane nanocluster for synaptic vesicle entry
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  152. www.sciencedirect.com www.sciencedirect.com
    Actuation of single downstream nodes in growth factor network steers immune cell migration
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    MND1 and PSMC3IP control PARP inhibitor sensitivity in mitotic cells
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  154. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A rabies virus–based toolkit for efficient retrograde... : Neural Regeneration Research
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  155. www.biorxiv.org www.biorxiv.org
    L1 retrotransposons drive human neuronal transcriptome complexity and functional diversification
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  156. www.sciencedirect.com www.sciencedirect.com
    TOPK inhibits TNF-α-induced granulosa cell apoptosis via regulation SIRT1/p53
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    sciencedirect.com/science/article/pii/S0006291X23005508
  157. Apr 2023
  158. www.sciencedirect.com www.sciencedirect.com
    CX3CR1 deficiency-induced TIL tumor restriction as a novel addition for CAR-T design in solid malignancies
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    sciencedirect.com/science/article/pii/S2589004223005205
  159. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Primary Glial Cell and Glioblastoma Morphology in Cocultures Depends on Scaffold Design and Hydrogel Composition
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    1. scibot 20 Apr 2023
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  160. Mar 2023
  161. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulatory and coding sequences of TRNP1 co-evolve with brain size and cortical folding in mammals
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  162. www.sciencedirect.com www.sciencedirect.com
    Human T cell generation is restored in CD3δ severe combined immunodeficiency through adenine base editing
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  163. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause deadly disease
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  164. Jan 2023
  165. www.sciencedirect.com www.sciencedirect.com
    Neurotransmitter release progressively desynchronizes in induced human neurons during synapse maturation and aging
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  166. www.sciencedirect.com www.sciencedirect.com
    Protocol to study presynaptic protein synthesis in ex vivo mouse hippocampal slices using HaloTag technology
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  167. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Acute COG inactivation unveiled its immediate impact on Golgi and illuminated the nature of intra-Golgi recycling vesicles
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  168. Dec 2022
  169. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Caspase-Mediated Regulation and Cellular Heterogeneity of the cGAS/STING Pathway in Kaposi’s Sarcoma-Associated Herpesvirus Infection
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    1. scibot 31 Dec 2022
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  170. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor necrosis factor is a necroptosis-associated alarmin
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  171. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Generation and Analysis of hTERT-RPE1 VPS54 Knock-Out and Rescued Cell Lines
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      DOI: 10.1007/978-1-0716-2639-9_22

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  172. link.springer.com link.springer.com
    Rapid COG Depletion in Mammalian Cell by Auxin-Inducible Degradation System
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  173. 52.53.155.43 52.53.155.43
    can-22-0455-html.html
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  174. Nov 2022
  175. www.sciencedirect.com www.sciencedirect.com
    Systematic generation and imaging of tandem repeats reveal base-pairing properties that promote RNA aggregation
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  176. Oct 2022
  177. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lentiviral vector mediated gene therapy for type I Dent disease effectively ameliorates Dent disease-like phenotypes for three months in ClC-5 null mice
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  178. journals.asm.org journals.asm.org
    Caspase-Mediated Regulation and Cellular Heterogeneity of the cGAS/STING Pathway in Kaposi’s Sarcoma-Associated Herpesvirus Infection
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      RRID:Addgene_12251

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  179. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CASK loss of function differentially regulates neuronal maturation and synaptic function in human induced cortical excitatory neurons
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  180. www.sciencedirect.com www.sciencedirect.com
    Angiotensin II receptor type 1 blockade regulates Klotho expression to induce TSC2-deficient cell death
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  181. www.sciencedirect.com www.sciencedirect.com
    In vitro neurons learn and exhibit sentience when embodied in a simulated game-world
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  182. www.nature.com www.nature.com
    Systematic discovery of recombinases for efficient integration of large DNA sequences into the human genome
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  183. Sep 2022
  184. www.sciencedirect.com www.sciencedirect.com
    Determining glioma cell invasion and proliferation in ex vivo organotypic mouse brain slices using whole-mount immunostaining and tissue clearing
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  185. www.sciencedirect.com www.sciencedirect.com
    S1-END-seq reveals DNA secondary structures in human cells
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  186. Aug 2022
  187. onlinelibrary.wiley.com onlinelibrary.wiley.com
    BNIP-2 Activation of Cellular Contractility Inactivates YAP for H9c2 Cardiomyoblast Differentiation
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  188. link.springer.com link.springer.com
    CDK7 inhibition augments response to multidrug chemotherapy in pancreatic cancer
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      DOI: 10.1186/s13046-022-02443-w

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    link.springer.com/article/10.1186/s13046-022-02443-w
  189. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Emergence of immune escape at dominant SARS-CoV-2 killer T-cell epitope
    1
    1. scibot 06 Aug 2022
      RRID:Addgene_12251

      DOI: 10.1016/j.cell.2022.07.002

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    ncbi.nlm.nih.gov/pmc/articles/PMC9279490/
  190. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A CRISPR-Cas12a-based diagnostic method for multiple genotypes of severe fever with thrombocytopenia syndrome virus
    1
    1. scibot 06 Aug 2022
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      DOI: 10.1371/journal.pntd.0010666

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    ncbi.nlm.nih.gov/pmc/articles/PMC9345333/
  191. academic.oup.com academic.oup.com
    FOXL2 and FOXA1 cooperatively assemble on the TP53 promoter in alternative dimer configurations
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    1. scibot 04 Aug 2022
      RRID:Addgene_12251

      DOI: 10.1093/nar/gkac673

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    academic.oup.com/nar/advance-article/doi/10.1093/nar/gkac673/6654407
  192. Jul 2022
  193. www.sciencedirect.com www.sciencedirect.com
    Aberrant human ClpP activation disturbs mitochondrial proteome homeostasis to suppress pancreatic ductal adenocarcinoma
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    1. scibot 30 Jul 2022
      RRID:Addgene_12251

      DOI: 10.1016/j.chembiol.2022.07.002

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    sciencedirect.com/science/article/pii/S2451945622002458
  194. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 27 Jul 2022
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15896
  195. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-Wide CRISPR Screening Identifies DCK and CCNL1 as Genes That Contribute to Gemcitabine Resistance in Pancreatic Cancer
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    1. scibot 12 Jul 2022
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      DOI: 10.3390/cancers14133152

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    ncbi.nlm.nih.gov/pmc/articles/PMC9264918/
  196. Jun 2022
  197. www.sciencedirect.com www.sciencedirect.com
    Oxidative stress from DGAT1 oncoprotein inhibition in melanoma suppresses tumor growth when ROS defenses are also breached
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    1. scibot 22 Jun 2022
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    sciencedirect.com/science/article/pii/S2211124722007811
  198. May 2022
  199. www.sciencedirect.com www.sciencedirect.com
    Aspartate metabolism in endothelial cells activates the mTORC1 pathway to initiate translation during angiogenesis
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    1. scibot 19 May 2022
      AddgeneCat. #12251

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    sciencedirect.com/science/article/pii/S1534580722002866
  200. www.sciencedirect.com www.sciencedirect.com
    Synthetic Carbohydrate Binding Agents neutralize SARS-CoV-2 by inhibiting binding of the spike protein to ACE2.
    2
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      RRID:Addgene_12251

      DOI: 10.1016/j.isci.2022.104239

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      RRID:Addgene_12251

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    sciencedirect.com/science/article/pii/S2589004222005090
  201. Apr 2022
  202. www.sciencedirect.com www.sciencedirect.com
    Synaptic vesicle binding of α-synuclein is modulated by β- and γ-synucleins
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    1. scibot 19 Apr 2022
      Addgene_12251

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    sciencedirect.com/science/article/pii/S2211124722004272
  203. www.sciencedirect.com www.sciencedirect.com
    Neurexins play a crucial role in cerebellar granule cell survival by organizing autocrine machinery for neurotrophins
    2
    1. scibot 07 Apr 2022
      Plasmid_12251

      DOI: 10.1016/j.celrep.2022.110624

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      RRID:Addgene_12

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    sciencedirect.com/science/article/pii/S2211124722003722
  204. Mar 2022
  205. onlinelibrary.wiley.com onlinelibrary.wiley.com
    PMS2 variant results in loss of ATPase activity without compromising mismatch repair
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    1. scibot 26 Mar 2022
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    onlinelibrary.wiley.com/doi/10.1002/mgg3.1908
  206. www.nature.com www.nature.com
    Field validation of the performance of paper-based tests for the detection of the Zika and chikungunya viruses in serum samples
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      DOI: 10.1038/s41551-022-00850-0

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    nature.com/articles/s41551-022-00850-0
  207. www.sciencedirect.com www.sciencedirect.com
    Generation of highly pure motor neurons from human induced pluripotent stem cells
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    sciencedirect.com/science/article/pii/S2666166722001034
  208. www.sciencedirect.com www.sciencedirect.com
    Deletion of STAT3 from Foxd1 cell population protects mice from kidney fibrosis by inhibiting pericytes trans-differentiation and migration
    1
    1. scibot 09 Mar 2022
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    sciencedirect.com/science/article/pii/S2211124722002066
  209. www.sciencedirect.com www.sciencedirect.com
    Human cytomegalovirus forms phase-separated compartments at viral genomes to facilitate viral replication
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      RRID:Addgene_12251

      DOI: 10.1016/j.celrep.2022.110469

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    sciencedirect.com/science/article/pii/S2211124722002029
  210. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Natural Chemotherapeutic Capsaicin Activates AMPK through LKB1 Kinase and TRPV1 Receptors in Prostate Cancer Cells
    1
    1. scibot 04 Mar 2022
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      DOI: 10.3390/pharmaceutics14020329

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    ncbi.nlm.nih.gov/pmc/articles/PMC8880011/
  211. elifesciences.org elifesciences.org
    Pathway-specific effects of ADSL deficiency on neurodevelopment
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    1. scibot 04 Mar 2022
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      DOI: 10.7554/eLife.70518

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    elifesciences.org/articles/70518
  212. Feb 2022
  213. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A zebrafish embryo screen utilizing gastrulation identifies the HTR2C inhibitor pizotifen as a suppressor of EMT-mediated metastasis
    1
    1. scibot 13 Feb 2022
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      DOI: 10.7554/eLife.70151

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    ncbi.nlm.nih.gov/pmc/articles/PMC8824480/
  214. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway
    2
    1. scibot 11 Feb 2022
      12251

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      12251

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    pubmed.ncbi.nlm.nih.gov/35139355/
  215. www.sciencedirect.com www.sciencedirect.com
    Development of human alveolar epithelial cell models to study distal lung biology and disease
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      DOI: 10.1016/j.isci.2022.103780

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    sciencedirect.com/science/article/pii/S2589004222000505
  216. onlinelibrary.wiley.com onlinelibrary.wiley.com
    ERα inhibits mesenchymal and amoeboidal movement of liver cancer cell via Gα12
    1
    1. scibot 03 Feb 2022
      plasmid_12251

      DOI: 10.1002/ijc.33929

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    onlinelibrary.wiley.com/doi/10.1002/ijc.33929
  217. journals.biologists.com journals.biologists.com
    Contribution of protein-protein interactions to the endothelial barrier-stabilizing function of KRIT1
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    1. scibot 01 Feb 2022
      RRID:Addgene_12251

      DOI: 10.1242/jcs.258816

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    journals.biologists.com/jcs/article/135/2/jcs258816/274104/Contribution-of-protein-protein-interactions-to
  218. Jan 2022
  219. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR-Cas9 Screen Identifies DYRK1A as a Target for Radiotherapy Sensitization in Pancreatic Cancer
    1
    1. scibot 22 Jan 2022
      RRID:Addgene_12251

      DOI: 10.3390/cancers14020326

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    ncbi.nlm.nih.gov/pmc/articles/PMC8773906/