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  2. aacrjournals.org aacrjournals.org
    H3.3 G34W Promotes Growth and Impedes Differentiation of Osteoblast-Like Mesenchymal Progenitors in Giant Cell Tumor of Bone
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    1. scibot 02 Oct 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1158/2159-8290.CD-20-0461

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    aacrjournals.org/cancerdiscovery/article/10/12/1968/2414/H3-3-G34W-Promotes-Growth-and-Impedes
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    A human organoid drug screen identifies α2-adrenergic receptor signaling as a therapeutic target for cartilage regeneration
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    1. scibot 02 Oct 2024
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      DOI: 10.1016/j.stem.2024.09.001

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    sciencedirect.com/science/article/pii/S1934590924003151
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multivalent MVA-vectored vaccine elicits EBV neutralizing antibodies in rhesus macaques that reduce EBV infection in humanized mice
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    1. scibot 02 Oct 2024
      RRID:IMSR_JAX:005557

      DOI: 10.3389/fimmu.2024.1445209

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    ncbi.nlm.nih.gov/pmc/articles/PMC11427267/
  5. www.biorxiv.org www.biorxiv.org
    Engineered Receptors for Soluble Cell-to-Cell Communication
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    1. scibot 28 Sep 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1101/2024.09.17.613377

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  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Induction of immortal-like and functional CAR T cells by defined factors
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    1. scibot 27 Sep 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1084/jem.20232368

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    ncbi.nlm.nih.gov/pmc/articles/PMC10965394/
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    VHL synthetic lethality screens uncover CBF-β as a negative regulator of STING
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    1. scibot 26 Sep 2024
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      DOI: 10.1101/2024.09.03.610968

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    ncbi.nlm.nih.gov/pmc/articles/PMC11398426/
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    A benzarone derivative inhibits EYA to suppress tumor growth in SHH medulloblastoma
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    1. scibot 25 Sep 2024
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      DOI: 10.1158/0008-5472.CAN-22-3784

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    ncbi.nlm.nih.gov/pmc/articles/PMC10948029/
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    Novel immunotherapeutics against LGR5 to target multiple cancer types
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    1. scibot 25 Sep 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1038/s44321-024-00121-2

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  10. Sep 2024
  11. www.sciencedirect.com www.sciencedirect.com
    Integrative identification of non-coding regulatory regions driving metastatic prostate cancer
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    1. scibot 17 Sep 2024
      Strain#005557

      DOI: 10.1016/j.celrep.2024.114764

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    sciencedirect.com/science/article/pii/S221112472401115X
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    Rewired glutamate metabolism diminishes cytostatic action of L-asparaginase
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    1. scibot 17 Sep 2024
      JAX:005557

      DOI: 10.1016/j.canlet.2024.217242

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    sciencedirect.com/science/article/pii/S0304383524006372
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    PRMT5 supports multiple oncogenic pathways in mantle cell lymphoma
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    1. scibot 12 Sep 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1182/blood.2022019419

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    ncbi.nlm.nih.gov/pmc/articles/PMC10517215/
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    Aberrant L-Fucose accumulation and increased core fucosylation are metabolic liabilities in mesenchymal glioblastoma
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    1. scibot 12 Sep 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1158/0008-5472.CAN-22-0677

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    aacrjournals.org/cancerres/article/83/2/195/715074/Aberrant-L-Fucose-Accumulation-and-Increased-Core
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    Bifunctional inhibitor reveals NEK2 as a therapeutic target and regulator of oncogenic pathways in lymphoma
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    1. scibot 05 Sep 2024
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      DOI: 10.1158/1535-7163.MCT-23-0299

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    ncbi.nlm.nih.gov/pmc/articles/PMC10932871/
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting AKR1B10 by drug repurposing with epalrestat overcomes chemoresistance in non-small cell lung cancer patient-derived tumor organoids
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    1. scibot 05 Sep 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1158/1078-0432.CCR-23-3980

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    ncbi.nlm.nih.gov/pmc/articles/PMC11369614/
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    A bispecific antibody targeting EGFR and AXL delays resistance to osimertinib
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    1. scibot 04 Sep 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.xcrm.2024.101703

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    sciencedirect.com/science/article/pii/S2666379124004245
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    Smarcd1 subunit of SWI/SNF chromatin-remodeling complexes collaborates with E2a to promote murine lymphoid specification
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      JAX:005557

      DOI: 10.1016/j.devcel.2024.08.007

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    sciencedirect.com/science/article/pii/S1534580724004908
  19. Aug 2024
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Role of Forkhead Box P3 in Interferon γ-mediated PD-L1 Expression and Bladder Cancer Epithelial-to-Mesenchymal Transition
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    1. scibot 28 Aug 2024
      JAX_005557

      DOI: 10.1158/2767-9764.CRC-23-0493

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    ncbi.nlm.nih.gov/pmc/articles/PMC11345674/
  21. www.cell.com www.cell.com
    Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies
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    1. scibot 22 Aug 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.cell.2020.02.019

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    cell.com/cell/fulltext/S0092-8674(20)30163-X
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    Interleukin-21 engineering enhances NK cell activity against glioblastoma via CEBPD
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    1. scibot 21 Aug 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.ccell.2024.07.007

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    sciencedirect.com/science/article/pii/S1535610824002721
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    Nuclear PKM2 binds pre-mRNA at folded G-quadruplexes and reveals their gene regulatory role
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    1. scibot 20 Aug 2024
      005557

      DOI: 10.1016/j.molcel.2024.07.025

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    sciencedirect.com/science/article/pii/S1097276524006233
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anti-EGFR Antibody–Drug Conjugate Carrying an Inhibitor Targeting CDK Restricts Triple-Negative Breast Cancer Growth
    1
    1. scibot 18 Aug 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1158/1078-0432.CCR-23-3110

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    ncbi.nlm.nih.gov/pmc/articles/PMC11292198/
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    Time- and cell-specific activation of BMP signaling restrains chondrocyte hypertrophy
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    1. scibot 13 Aug 2024
      005557

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    sciencedirect.com/science/article/pii/S2589004224017620
  26. www.biorxiv.org www.biorxiv.org
    Senescent fibroblasts in the tumor stroma rewire lung cancer metabolism and plasticity
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    1. scibot 13 Aug 2024
      Jackson Laboratory, catalog #005557

      DOI: 10.1101/2024.07.29.605645

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    biorxiv.org/content/10.1101/2024.07.29.605645v1
  27. www.nature.com www.nature.com
    A humanized mouse that mounts mature class-switched, hypermutated and neutralizing antibody responses
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      RRID: IMSR_JAX: 005557

      DOI: 10.1038/s41590-024-01880-3

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    nature.com/articles/s41590-024-01880-3
  28. cancerci.biomedcentral.com cancerci.biomedcentral.com
    Targeting of H19/cell adhesion molecules circuitry by GSK-J4 epidrug inhibits metastatic progression in prostate cancer
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    1. scibot 02 Aug 2024
      RRID: IMSR_JAX:005557

      DOI: 10.1186/s12935-024-03231-6

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    cancerci.biomedcentral.com/articles/10.1186/s12935-024-03231-6
  29. www.biorxiv.org www.biorxiv.org
    Salmonella enterica serovar Typhi uses two type 3 secretion systems to replicate in human macrophages and to colonize humanized mice
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    1. scibot 02 Aug 2024
      Humanized-NOD-scid IL2rγ-null mice

      DOI: 10.1101/2023.06.06.543980

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    biorxiv.org/content/10.1101/2023.06.06.543980v1
  30. Jul 2024
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    N-Myristoyltransferase Inhibition causes Mitochondrial Iron Overload and Parthanatos in TIM17A-dependent Aggressive Lung Carcinoma
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    1. scibot 27 Jul 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1158/2767-9764.CRC-23-0428

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    ncbi.nlm.nih.gov/pmc/articles/PMC11270646/
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    Protocol for assessing GD2 on formalin-fixed paraffin-embedded tissue sections using immunofluorescence staining
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    1. scibot 26 Jul 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.xpro.2024.103199

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    sciencedirect.com/science/article/pii/S2666166724003642
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    Integrated transcriptomics of human blood vessels defines a spatially controlled niche for early mesenchymal progenitor cells
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    1. scibot 26 Jul 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.devcel.2024.06.015

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    sciencedirect.com/science/article/pii/S1534580724003939
  34. www.sciencedirect.com www.sciencedirect.com
    PAI-1 uncouples integrin-β1 from restrain by membrane-bound β-catenin to promote collagen fibril remodeling in obesity-related neoplasms
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      005557

      DOI: 10.1016/j.celrep.2024.114527

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    sciencedirect.com/science/article/pii/S2211124724008568
  35. www.sciencedirect.com www.sciencedirect.com
    Targeting the mSWI/SNF complex in POU2F-POU2AF transcription factor-driven malignancies
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.ccell.2024.06.006

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    sciencedirect.com/science/article/pii/S1535610824002319
  36. www.sciencedirect.com www.sciencedirect.com
    Preclinical proof of principle for orally delivered Th17 antagonist miniproteins
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    1. scibot 23 Jul 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.cell.2024.05.052

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    sciencedirect.com/science/article/pii/S0092867424006317
  37. www.sciencedirect.com www.sciencedirect.com
    Protocol to construct humanized mice with adult CD34+ hematopoietic stem and progenitor cells
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      JAX:005557

      DOI: 10.1016/j.xpro.2024.103155

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    sciencedirect.com/science/article/pii/S2666166724003204
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metformin synergizes with gilteritinib in treating FLT3-mutated leukemia via targeting PLK1 signaling
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.xcrm.2024.101645

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    ncbi.nlm.nih.gov/pmc/articles/PMC11293342/
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRDM6 promotes medulloblastoma by repressing chromatin accessibility and altering gene expression
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      RRID:IMSR_JAX:005557

      DOI: 10.1038/s41598-024-66811-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC11239875/
  40. www.biorxiv.org www.biorxiv.org
    Organoid Models Derived from Primary Tumors and Patient-Derive Xenograft Tumors Reflect Platinum Sensitivity of Ovarian Cancer Patients
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      RRID:IMSR_JAX:005557

      DOI: 10.1101/2024.06.28.601283

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    biorxiv.org/content/10.1101/2024.06.28.601283v1
  41. www.cell.com www.cell.com
    Elevating PLK1 overcomes BETi resistance in prostate cancer via triggering BRD4 phosphorylation-dependent degradation in mitosis
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    1. scibot 12 Jul 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.celrep.2024.114431

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    cell.com/cell-reports/fulltext/S2211-1247(24)00760-5
  42. www.mdpi.com www.mdpi.com
    HER4 Affects Sensitivity to Tamoxifen and Abemaciclib in Luminal Breast Cancer Cells and Restricts Tumor Growth in MCF-7-Based Humanized Tumor Mice
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      RRID:IMSR_JAX:005557

      DOI: 10.3390/ijms25137475

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    mdpi.com/1422-0067/25/13/7475
  43. www.cell.com www.cell.com
    Genetic ablation of adhesion ligands mitigates rejection of allogeneic cellular immunotherapies
    1
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      JAX:005557

      DOI: 10.1016/j.stem.2024.06.011

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    cell.com/cell-stem-cell/abstract/S1934-5909(24)00219-4
  44. Jun 2024
  45. www.nature.com www.nature.com
    A humanized mouse that mounts mature class-switched, hypermutated and neutralizing antibody responses
    1
    1. scibot 28 Jun 2024
      JAX:005557

      DOI: 10.1038/s41590-024-01880-3

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    nature.com/articles/s41590-024-01880-3
  46. www.sciencedirect.com www.sciencedirect.com
    TNF-NF-κB-p53 axis restricts in vivo survival of hPSC-derived dopamine neurons
    1
    1. scibot 21 Jun 2024
      JAX:005557

      DOI: 10.1016/j.cell.2024.05.030

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    sciencedirect.com/science/article/pii/S0092867424005750
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of Pip4k2c confers liver-metastatic organotropism through insulin-dependent PI3K-AKT pathway activation
    1
    1. scibot 15 Jun 2024
      JAX:005557

      DOI: 10.1038/s43018-023-00704-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC11175596/
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The exonuclease TREX1 constitutes an innate immune checkpoint limiting cGAS/STING-mediated antitumor immunity
    1
    1. scibot 08 Jun 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1158/2326-6066.CIR-23-1078

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    ncbi.nlm.nih.gov/pmc/articles/PMC11148535/
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nextflow pipeline for Visium and H&E data from patient-derived xenograft samples
    1
    1. scibot 08 Jun 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.crmeth.2024.100759

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  50. www.sciencedirect.com www.sciencedirect.com
    De novo and salvage purine synthesis pathways across tissues and tumors
    1
    1. scibot 04 Jun 2024
      005557

      DOI: 10.1016/j.cell.2024.05.011

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    sciencedirect.com/science/article/pii/S0092867424005208
  51. www.cell.com www.cell.com
    DARPin-fused T cell engager for adenovirus-mediated cancer therapy
    1
    1. scibot 04 Jun 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.omton.2024.200821

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    cell.com/molecular-therapy-family/oncology/abstract/S2950-3299(24)00063-8
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Enhancing PKA-dependent mesothelial barrier integrity reduces ovarian cancer spheroid transmesothelial migration via inhibition of contractility
    1
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.isci.2024.109950

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    ncbi.nlm.nih.gov/pmc/articles/PMC11134878/
  53. May 2024
  54. www.sciencedirect.com www.sciencedirect.com
    Tumor cells impair immunological synapse formation via central nervous system-enriched metabolite
    2
    1. scibot 31 May 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.ccell.2024.05.006

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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.ccell.2024.05.006

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    sciencedirect.com/science/article/pii/S1535610824001697
  55. www.biorxiv.org www.biorxiv.org
    SMAD4 and KRAS status shape malignant-stromal crosstalk in pancreatic cancer
    1
    1. scibot 23 May 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1101/2024.04.28.591518

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    biorxiv.org/content/10.1101/2024.04.28.591518v1
  56. aacrjournals.org aacrjournals.org
    Development of chromosome 1q+ specific treatment for highest risk pediatric posterior fossa ependymoma
    1
    1. scibot 23 May 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1158/1078-0432.CCR-23-3156

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    aacrjournals.org/clincancerres/article/30/8/1544/742119/Development-of-Chromosome-1q-Specific-Treatment
  57. 52.53.155.43 52.53.155.43
    cir-23-1078-html.html
    1
    1. scibot 23 May 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1158/2326-6066.cir-23-1078

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    52.53.155.43/ee0bd7762d373e957152429ed1d9032329c895e5/cir-23-1078-html.html
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An imbalance between proliferation and differentiation underlies the development of microRNA-defective pineoblastoma
    2
    1. scibot 23 May 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1101/2024.04.23.590638

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      RRID:IMSR_JAX:005557

      DOI: 10.1101/2024.04.23.590638

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    ncbi.nlm.nih.gov/pmc/articles/PMC11071395/
  59. www.sciencedirect.com www.sciencedirect.com
    linc-ADAIN, a human adipose lincRNA, regulates adipogenesis by modulating KLF5 and IL-8 mRNA stability
    1
    1. scibot 16 May 2024
      005557

      DOI: 10.1016/j.celrep.2024.114240

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    sciencedirect.com/science/article/pii/S2211124724005680
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neoadjuvant radiotherapy in ER+, HER2+, and triple-negative -specific breast cancer based humanized tumor mice enhances anti-PD-L1 treatment efficacy
    1
    1. scibot 15 May 2024
      JAX:005557

      DOI: 10.3389/fimmu.2024.1355130

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    ncbi.nlm.nih.gov/pmc/articles/PMC11089195/
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human CD4+ Memory Phenotype T cells use mitochondrial metabolism to generate sensitive IFN-γ responses
    1
    1. scibot 11 May 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.isci.2024.109775

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    ncbi.nlm.nih.gov/pmc/articles/PMC11079467/
  62. www.sciencedirect.com www.sciencedirect.com
    Inhibition of protein translational machinery in triple-negative breast cancer as a promising therapeutic strategy
    1
    1. scibot 10 May 2024
      005557

      DOI: 10.1016/j.xcrm.2024.101552

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    sciencedirect.com/science/article/pii/S2666379124002441
  63. www.sciencedirect.com www.sciencedirect.com
    Identification of WNK1 as a therapeutic target to suppress IgH/MYC expression in multiple myeloma
    1
    1. scibot 09 May 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.celrep.2024.114211

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    sciencedirect.com/science/article/pii/S2211124724005394
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Urolithin-A Promotes CD8+ T Cell–mediated Cancer Immunosurveillance via FOXO1 Activation
    1
    1. scibot 08 May 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1158/2767-9764.CRC-24-0022

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    ncbi.nlm.nih.gov/pmc/articles/PMC11067828/
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive Transcriptomic Analysis of EWSR1::WT1 Targets Identifies CDK4/6 Inhibitors as an Effective Therapy for Desmoplastic Small Round Cell Tumors
    1
    1. scibot 04 May 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1158/0008-5472.CAN-23-3334

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    ncbi.nlm.nih.gov/pmc/articles/PMC11063761/
  66. www.biorxiv.org www.biorxiv.org
    Imipridones inhibit tumor growth and improve survival in an orthotopic liver metastasis mouse model of human uveal melanoma
    1
    1. scibot 03 May 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1101/2024.01.12.575058

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    biorxiv.org/content/10.1101/2024.01.12.575058v1
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preclinical Multi-Omic Assessment of Pioglitazone in Skeletal Muscles of Mice Implanted with Human HER2/neu Overexpressing Breast Cancer Xenografts
    1
    1. scibot 03 May 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1101/2024.04.15.589557

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    ncbi.nlm.nih.gov/pmc/articles/PMC11042380/
  68. www.sciencedirect.com www.sciencedirect.com
    Molecular targets of glucocorticoids that elucidate their therapeutic efficacy in aggressive lymphomas
    1
    1. scibot 03 May 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.ccell.2024.04.007

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  69. Apr 2024
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In vitro platform to model the function of ionocytes in the human airway epithelium
    1
    1. scibot 30 Apr 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1186/s12931-024-02800-7

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    ncbi.nlm.nih.gov/pmc/articles/PMC11045446/
  71. www.sciencedirect.com www.sciencedirect.com
    Selective refueling of CAR T cells using ADA1 and CD26 boosts antitumor immunity
    1
    1. scibot 30 Apr 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.xcrm.2024.101530

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  72. www.sciencedirect.com www.sciencedirect.com
    Development of a chimeric cytokine receptor that captures IL-6 and enhances the antitumor response of CAR-T cells
    1
    1. scibot 26 Apr 2024
      Jackson LaboratoryStrain #:005557

      DOI: 10.1016/j.xcrm.2024.101526

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  73. www.sciencedirect.com www.sciencedirect.com
    Human anti-PSCA CAR macrophages possess potent antitumor activity against pancreatic cancer
    1
    1. scibot 25 Apr 2024
      Jackson LaboratoryStrain# 005557

      DOI: 10.1016/j.stem.2024.03.018

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    sciencedirect.com/science/article/pii/S1934590924001243
  74. www.pnas.org www.pnas.org
    NOVA1 acts as an oncogenic RNA-binding protein to regulate cholesterol homeostasis in human glioblastoma cells
    1
    1. scibot 25 Apr 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1073/pnas.2314695121

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    pnas.org/doi/abs/10.1073/pnas.2314695121
  75. link.springer.com link.springer.com
    Single-cell analysis reveals context-dependent, cell-level selection of mtDNA
    1
    1. scibot 25 Apr 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1038/s41586-024-07332-0

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    link.springer.com/article/10.1038/s41586-024-07332-0
  76. www.liebertpub.com www.liebertpub.com
    Biodistribution and Safety of Human Multi-Chimeric Cells (HMCC) After Systemic Intraosseous and Intravenous Administration in the Experimental Mouse Model
    2
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      RRID:ISMR_JAK:005557

      DOI: 10.1089/scd.2024.0007

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      RRID:ISMR_JAK:005557

      DOI: 10.1089/scd.2024.0007

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    liebertpub.com/doi/10.1089/scd.2024.0007
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression
    1
    1. scibot 24 Apr 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1093/narcan/zcae018

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  78. www.sciencedirect.com www.sciencedirect.com
    Differential RNA Expression Between Metastatic and Primary Neuroblastoma Cells
    1
    1. scibot 19 Apr 2024
      RRID:IMSR_JAX:005

      DOI: 10.1016/j.jss.2024.03.032

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  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Memory-like differentiation, tumor targeting monoclonal antibodies, and chimeric antigen receptors enhance natural killer cell responses to head and neck cancer
    1
    1. scibot 18 Apr 2024
      JAX:005557

      DOI: 10.1158/1078-0432.CCR-23-0156

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    ncbi.nlm.nih.gov/pmc/articles/PMC10796148/
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    iPSC-based modeling of preeclampsia identifies epigenetic defects in extravillous trophoblast differentiation
    1
    1. scibot 18 Apr 2024
      JAX:005557

      DOI: 10.1016/j.isci.2024.109569

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    ncbi.nlm.nih.gov/pmc/articles/PMC11016801/
  81. www.sciencedirect.com www.sciencedirect.com
    Osteopontin drives neuroinflammation and cell loss in MAPT-N279K frontotemporal dementia patient neurons
    1
    1. scibot 16 Apr 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.stem.2024.03.013

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    sciencedirect.com/science/article/pii/S1934590924000948
  82. www.sciencedirect.com www.sciencedirect.com
    Pharmacological induction of chromatin remodeling drives chemosensitization in triple-negative breast cancer
    1
    1. scibot 09 Apr 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.xcrm.2024.101504

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    sciencedirect.com/science/article/pii/S2666379124001733
  83. www.sciencedirect.com www.sciencedirect.com
    Targeting the GPI transamidase subunit GPAA1 abrogates the CD24 immune checkpoint in ovarian cancer
    1
    1. scibot 04 Apr 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.celrep.2024.114041

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    sciencedirect.com/science/article/pii/S2211124724003693
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    STAT3 couples activated tyrosine kinase signaling to the oncogenic core transcriptional regulatory circuitry of anaplastic large cell lymphoma
    1
    1. scibot 03 Apr 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.xcrm.2024.101472

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    ncbi.nlm.nih.gov/pmc/articles/PMC10983107/
  85. www.nature.com www.nature.com
    Targeting branched N-glycans and fucosylation sensitizes ovarian tumors to immune checkpoint blockade
    1
    1. scibot 03 Apr 2024
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      DOI: 10.1038/s41467-024-47069-y

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    nature.com/articles/s41467-024-47069-y
  86. www.sciencedirect.com www.sciencedirect.com
    Targeting DNMT3A-mediated oxidative phosphorylation to overcome ibrutinib resistance in mantle cell lymphoma
    1
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      Jackson Laboratory5557

      DOI: 10.1016/j.xcrm.2024.101484

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    sciencedirect.com/science/article/pii/S2666379124001307
  87. Mar 2024
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MARCH2, a novel oncogene-regulated SNAIL E3 ligase, suppresses triple negative breast cancer metastases
    1
    1. scibot 31 Mar 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1158/2767-9764.CRC-23-0090

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  89. www.sciencedirect.com www.sciencedirect.com
    Histone lysine demethylase 4 family proteins maintain the transcriptional program and adrenergic cellular state of MYCN-amplified neuroblastoma
    1
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      005557

      DOI: 10.1016/j.xcrm.2024.101468

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    sciencedirect.com/science/article/pii/S2666379124001149
  90. www.sciencedirect.com www.sciencedirect.com
    Multiparatopic antibodies induce targeted downregulation of programmed death-ligand 1
    1
    1. scibot 28 Mar 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.chembiol.2024.02.014

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    sciencedirect.com/science/article/pii/S2451945624000886
  91. www.nature.com www.nature.com
    Regulatory T cells expressing CD19-targeted chimeric antigen receptor restore homeostasis in Systemic Lupus Erythematosus
    1
    1. scibot 28 Mar 2024
      RRID:IMSR_JAX

      DOI: 10.1038/s41467-024-46448-9

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  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Drug-resistant EGFR mutations promote lung cancer by stabilizing interfaces in ligand-free kinase-active EGFR oligomers
    1
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      DOI: 10.1038/s41467-024-46284-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC10951324/
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The bone ecosystem facilitates multiple myeloma relapse and the evolution of heterogeneous drug resistant disease
    1
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      DOI: 10.1038/s41467-024-46594-0

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    ncbi.nlm.nih.gov/pmc/articles/PMC10951361/
  94. www.sciencedirect.com www.sciencedirect.com
    FAM86A methylation of eEF2 links mRNA translation elongation to tumorigenesis
    1
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.molcel.2024.02.037

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    sciencedirect.com/science/article/pii/S1097276524001801
  95. www.pnas.org www.pnas.org
    CD73 contributes to the pathogenesis of fusion-negative rhabdomyosarcoma through the purinergic signaling pathway
    1
    1. scibot 21 Mar 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1073/pnas.2315925121

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    pnas.org/doi/abs/10.1073/pnas.2315925121
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metabolic reprogramming of cancer cells by JMJD6-mediated pre-mRNA splicing associated with therapeutic response to splicing inhibitor
    1
    1. scibot 17 Mar 2024
      RRID:IMSR_JAX:005557

      DOI: 10.7554/eLife.90993

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    ncbi.nlm.nih.gov/pmc/articles/PMC10942784/
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Precision Enhancement of CAR-NK Cells through Non-Viral Engineering and Highly Multiplexed Base Editing
    1
    1. scibot 15 Mar 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1101/2024.03.05.582637

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  98. www.sciencedirect.com www.sciencedirect.com
    ARID1A orchestrates SWI/SNF-mediated sequential binding of transcription factors with ARID1A loss driving pre-memory B cell fate and lymphomagenesis
    1
    1. scibot 08 Mar 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.ccell.2024.02.010

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  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ALK upregulates POSTN and WNT signaling to drive neuroblastoma
    1
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.celrep.2024.113927

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    ncbi.nlm.nih.gov/pmc/articles/PMC11101011/
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neutralizing antibodies impair the oncolytic efficacy of reovirus but permit effective combination with T cell-based immunotherapies
    1
    1. scibot 06 Mar 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1158/2326-6066.CIR-23-0480

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    ncbi.nlm.nih.gov/pmc/articles/PMC10911706/
  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Engraftment of adult hematopoietic stem and progenitor cells in a novel model of humanized mice
    1
    1. scibot 06 Mar 2024
      JAX:005557

      DOI: 10.1016/j.isci.2024.109238

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    ncbi.nlm.nih.gov/pmc/articles/PMC10904995/
  102. www.sciencedirect.com www.sciencedirect.com
    Identification and characterization of a potent and selective HUNK inhibitor for treatment of HER2+ breast cancer
    2
    1. scibot 06 Mar 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.chembiol.2024.01.001

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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.chembiol.2024.01.001

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    sciencedirect.com/science/article/pii/S2451945624000370
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chromosomal instability in aneuploid acute lymphoblastic leukemia associates with disease progression
    1
    1. scibot 03 Mar 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1038/s44321-023-00006-w

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    ncbi.nlm.nih.gov/pmc/articles/PMC10897411/
  104. 52.53.155.43 52.53.155.43
    FEBS Press
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      RRID:IMSR_JAX:005557

      DOI: 10.1002/1878-0261.13561

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    52.53.155.43/47007dbc2cda4f961c79d2e8158521ca8af7c5b7/Molecular Oncology - 2023 - Bots - Preclinical evaluation of the gorilla-derived HAdV-B AdV-lumc007 oncolytic adenovirus -html.html
  105. Feb 2024
  106. aacrjournals.org aacrjournals.org
    Single-cell transcriptomics reveals the heterogeneity of the immune landscape of IDH-wildtype high-grade gliomas
    2
    1. scibot 27 Feb 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1158/2326-6066.CIR-23-0211

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      RRID:IMSR_JAX:005557

      DOI: 10.1158/2326-6066.CIR-23-0211

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    aacrjournals.org/cancerimmunolres/article/12/2/232/733764/Single-Cell-Transcriptomics-Reveals-the
  107. www.sciencedirect.com www.sciencedirect.com
    A versatile CRISPR-Cas13d platform for multiplexed transcriptomic regulation and metabolic engineering in primary human T cells
    1
    1. scibot 22 Feb 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.cell.2024.01.035

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    sciencedirect.com/science/article/pii/S0092867424001028
  108. www.sciencedirect.com www.sciencedirect.com
    SLC25A51 decouples the mitochondrial NAD+/NADH ratio to control proliferation of AML cells
    1
    1. scibot 16 Feb 2024
      Jackson Laboratories# 005557

      DOI: 10.1016/j.cmet.2024.01.013

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    sciencedirect.com/science/article/pii/S1550413124000135
  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stromal-derived MAOB promotes prostate cancer growth and progression
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    1. scibot 14 Feb 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1126/sciadv.adi4935

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  110. www.sciencedirect.com www.sciencedirect.com
    Signaling via a CD27-TRAF2-SHP-1 axis during naive T cell activation promotes memory-associated gene regulatory networks
    2
    1. scibot 14 Feb 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.immuni.2024.01.011

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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.immuni.2024.01.011

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    sciencedirect.com/science/article/pii/S1074761324000360
  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional Heterogeneity in MET Pathway Activation in PDX Models of Osimertinib Resistant EGFR-Driven Lung Cancer
    1
    1. scibot 11 Feb 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1158/2767-9764.CRC-23-0321

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    ncbi.nlm.nih.gov/pmc/articles/PMC10851855/
  112. www.biorxiv.org www.biorxiv.org
    HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance
    3
    1. scibot 09 Feb 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1101/2023.12.05.570182

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      RRID:IMSR_JAX:005557

      DOI: 10.1101/2023.12.05.570182

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      RRID:IMSR_JAX:005557

      DOI: 10.1101/2023.12.05.570182

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    biorxiv.org/content/10.1101/2023.12.05.570182v1
  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNA Helicase DDX3 Regulates RAD51 Localization and DNA Damage Repair in Ewing Sarcoma
    1
    1. scibot 08 Feb 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.isci.2024.108925

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    ncbi.nlm.nih.gov/pmc/articles/PMC10844834/
  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of choline metabolism in an angioimmunoblastic T-cell lymphoma preclinical model reveals a new metabolic vulnerability as possible target for treatment
    1
    1. scibot 08 Feb 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1186/s13046-024-02952-w

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    ncbi.nlm.nih.gov/pmc/articles/PMC10845598/
  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FPFT-2216, a novel anti-lymphoma compound, induces simultaneous degradation of IKZF1/3 and CK1α to activate p53 and inhibit NF-κB signaling
    1
    1. scibot 08 Feb 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1158/2767-9764.CRC-23-0264

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    ncbi.nlm.nih.gov/pmc/articles/PMC10846380/
  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting N-linked Glycosylation for the Therapy of Aggressive Lymphomas
    1
    1. scibot 06 Feb 2024
      RRID:IMSR_JAX

      DOI: 10.1158/2159-8290.CD-22-1401

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    ncbi.nlm.nih.gov/pmc/articles/PMC10524254/
  117. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ORAOV1, CCND1, and MIR548K Are the Driver Oncogenes of the 11q13 Amplicon in Squamous Cell Carcinoma
    1
    1. scibot 03 Feb 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1158/1541-7786.MCR-23-0746

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  118. www.sciencedirect.com www.sciencedirect.com
    SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion
    1
    1. scibot 02 Feb 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.cell.2024.01.008

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    sciencedirect.com/science/article/pii/S0092867424000102
  119. Jan 2024
  120. www.sciencedirect.com www.sciencedirect.com
    Inosine induces stemness features in CAR-T cells and enhances potency
    1
    1. scibot 26 Jan 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.ccell.2024.01.002

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  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor cell–intrinsic PD-1 promotes Merkel cell carcinoma growth by activating downstream mTOR-mitochondrial ROS signaling
    2
    1. scibot 25 Jan 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1126/sciadv.adi2012

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      RRID:IMSR_JAX:005557

      DOI: 10.1126/sciadv.adi2012

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    ncbi.nlm.nih.gov/pmc/articles/PMC10798567/
  122. www.sciencedirect.com www.sciencedirect.com
    Cholinergic signaling via muscarinic M1 receptor confers resistance to docetaxel in prostate cancer
    1
    1. scibot 23 Jan 2024
      Jackson LaboratoryCat# 005557

      DOI: 10.1016/j.xcrm.2023.101388

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    sciencedirect.com/science/article/pii/S2666379123006171
  123. www.sciencedirect.com www.sciencedirect.com
    Selective induction of human renal interstitial progenitor-like cell lineages from iPSCs reveals development of mesangial and EPO-producing cells
    1
    1. scibot 19 Jan 2024
      Jackson Laboratory: Stock No: 005557

      DOI: 10.1016/j.celrep.2023.113602

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    sciencedirect.com/science/article/pii/S2211124723016145
  124. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fusion-negative rhabdomyosarcoma 3D organoids to predict effective drug combinations: A proof-of-concept on cell death inducers
    1
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.xcrm.2023.101339

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    ncbi.nlm.nih.gov/pmc/articles/PMC10772578/
  125. www.sciencedirect.com www.sciencedirect.com
    Metabolic reprogramming by histone deacetylase inhibition preferentially targets NRF2-activated tumors
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    1. scibot 11 Jan 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.celrep.2023.113629

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    sciencedirect.com/science/article/pii/S2211124723016406
  126. www.sciencedirect.com www.sciencedirect.com
    Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma
    1
    1. scibot 11 Jan 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.molcel.2023.12.003

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    sciencedirect.com/science/article/pii/S1097276523010225
  127. www.sciencedirect.com www.sciencedirect.com
    Kidney organoid models reveal cilium-autophagy metabolic axis as a therapeutic target for PKD both in vitro and in vivo
    1
    1. scibot 11 Jan 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.stem.2023.12.003

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    sciencedirect.com/science/article/pii/S1934590923004332
  128. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    β-catenin-driven differentiation is a tissue-specific epigenetic vulnerability in adrenal cancer
    1
    1. scibot 10 Jan 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1158/0008-5472.CAN-22-2712

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    ncbi.nlm.nih.gov/pmc/articles/PMC10330305/
  129. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting DNA Repair and Survival Signaling in Diffuse Intrinsic Pontine Gliomas to Prevent Tumor Recurrence
    1
    1. scibot 05 Jan 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1158/1535-7163.MCT-23-0026

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    ncbi.nlm.nih.gov/pmc/articles/PMC10762335/
  130. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Brentuximab Vedotin–Driven Microtubule Disruption Results in Endoplasmic Reticulum Stress Leading to Immunogenic Cell Death and Antitumor Immunity
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    1. scibot 05 Jan 2024
      RRID:IMSR_JAX:005557

      DOI: 10.1158/1535-7163.MCT-23-0118

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    ncbi.nlm.nih.gov/pmc/articles/PMC10762337/
  131. Dec 2023
  132. www.embopress.org www.embopress.org
    Chromosomal instability in aneuploid acute lymphoblastic leukemia associates with disease progression
    1
    1. scibot 29 Dec 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1038/s44321-023-00006-w

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    embopress.org/doi/10.1038/s44321-023-00006-w
  133. www.sciencedirect.com www.sciencedirect.com
    The sinoatrial node extracellular matrix promotes pacemaker phenotype and protects automaticity in engineered heart tissues from cyclic strain
    2
    1. scibot 20 Dec 2023
      The Jackson LaboratoryStrain # 005557

      DOI: 10.1016/j.celrep.2023.113505

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      JAX:005557

      DOI: 10.1016/j.celrep.2023.113505

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    sciencedirect.com/science/article/pii/S2211124723015176
  134. www.sciencedirect.com www.sciencedirect.com
    FLT3L-dependent dendritic cells control tumor immunity by modulating Treg and NK cell homeostasis
    1
    1. scibot 20 Dec 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.xcrm.2023.101256

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    sciencedirect.com/science/article/pii/S2666379123004330
  135. www.sciencedirect.com www.sciencedirect.com
    AA2P-mediated DNA demethylation synergizes with stem cell agonists to promote expansion of hematopoietic stem cells
    3
    1. scibot 17 Dec 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.crmeth.2023.100663

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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.crmeth.2023.100663

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    3. scibot 17 Dec 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.crmeth.2023.100663

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    sciencedirect.com/science/article/pii/S2667237523003405
  136. link.springer.com link.springer.com
    Cas9-induced targeted integration of large DNA payloads in primary human T cells via homology-mediated end-joining DNA repair
    1
    1. scibot 16 Dec 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1038/s41551-023-01157-4

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    link.springer.com/article/10.1038/s41551-023-01157-4
  137. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Interleukin-30 subverts prostate cancer-endothelium crosstalk by fostering angiogenesis and activating immunoregulatory and oncogenic signaling pathways
    1
    1. scibot 15 Dec 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1186/s13046-023-02902-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC10714661/
  138. link.springer.com link.springer.com
    Generation of antigen-specific mature T cells from RAG1−/−RAG2−/−B2M−/− stem cells by engineering their microenvironment
    1
    1. scibot 08 Dec 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1038/s41551-023-01146-7

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    link.springer.com/article/10.1038/s41551-023-01146-7
  139. www.sciencedirect.com www.sciencedirect.com
    Prospective isolation of neural stem and progenitor cells from the developing human brain
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    1. scibot 02 Dec 2023
      JAX:005557

      DOI: 10.1016/j.xpro.2023.102674

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    sciencedirect.com/science/article/pii/S266616672300641X
  140. www.sciencedirect.com www.sciencedirect.com
    ALK inhibitors increase ALK expression and sensitize neuroblastoma cells to ALK.CAR-T cells
    1
    1. scibot 02 Dec 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.ccell.2023.11.004

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    sciencedirect.com/science/article/pii/S1535610823003951
  141. www.biorxiv.org www.biorxiv.org
    H3K27me3 spreading organizes canonical PRC1 chromatin architecture to regulate developmental programs
    1
    1. scibot 02 Dec 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1101/2023.11.28.567931

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    biorxiv.org/content/10.1101/2023.11.28.567931v1
  142. link.springer.com link.springer.com
    The DNA/RNA helicase DHX9 orchestrates the KDM2B-mediated transcriptional regulation of YAP1 in Ewing sarcoma
    1
    1. scibot 02 Dec 2023
      JAX:005557

      DOI: 10.1038/s41388-023-02894-1

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    link.springer.com/article/10.1038/s41388-023-02894-1
  143. Nov 2023
  144. www.sciencedirect.com www.sciencedirect.com
    SERPINB3-MYC axis induces the basal-like/squamous subtype and enhances disease progression in pancreatic cancer
    1
    1. scibot 28 Nov 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.celrep.2023.113434

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    sciencedirect.com/science/article/pii/S2211124723014468
  145. www.sciencedirect.com www.sciencedirect.com
    Temporal evolution reveals bifurcated lineages in aggressive neuroendocrine small cell prostate cancer trans-differentiation
    1
    1. scibot 28 Nov 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.ccell.2023.10.009

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    sciencedirect.com/science/article/pii/S1535610823003653
  146. www.sciencedirect.com www.sciencedirect.com
    Allosteric SHP2 inhibition increases apoptotic dependency on BCL2 and synergizes with venetoclax in FLT3- and KIT-mutant AML
    1
    1. scibot 22 Nov 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.xcrm.2023.101290

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    sciencedirect.com/science/article/pii/S2666379123004846
  147. www.biorxiv.org www.biorxiv.org
    Induction of immortal-like and functional CAR-T cells by defined factors
    1
    1. scibot 17 Nov 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1101/2023.11.06.565785

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    biorxiv.org/content/10.1101/2023.11.06.565785v1
  148. www.biorxiv.org www.biorxiv.org
    One infusion of engineered long-lasting and multifunctional T cells cures asthma in mice
    1
    1. scibot 17 Nov 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1101/2023.11.06.565713

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    biorxiv.org/content/10.1101/2023.11.06.565713v1
  149. link.springer.com link.springer.com
    Human Wharton’s jelly-derived mesenchymal stromal cells promote bone formation in immunodeficient mice when administered into a bone microenvironment
    1
    1. scibot 12 Nov 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1186/s12967-023-04672-9

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    link.springer.com/article/10.1186/s12967-023-04672-9
  150. link.springer.com link.springer.com
    Multimeric immunotherapeutic complexes activating natural killer cells towards HIV-1 cure
    1
    1. scibot 10 Nov 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1186/s12967-023-04669-4

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  151. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In Vivo Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic Target
    2
    1. scibot 03 Nov 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1158/2643-3230.BCD-22-0086

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    2. scibot 03 Nov 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1158/2643-3230.BCD-22-0086

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    ncbi.nlm.nih.gov/pmc/articles/PMC10150294/
  152. www.sciencedirect.com www.sciencedirect.com
    Targeting intracellular oncoproteins with dimeric IgA promotes expulsion from the cytoplasm and immune-mediated control of epithelial cancers
    1
    1. scibot 02 Nov 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.immuni.2023.09.013

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    sciencedirect.com/science/article/pii/S1074761323004181
  153. Oct 2023
  154. www.sciencedirect.com www.sciencedirect.com
    Tyrosine catabolism enhances genotoxic chemotherapy by suppressing translesion DNA synthesis in epithelial ovarian cancer
    1
    1. scibot 28 Oct 2023
      JAX:005557

      DOI: 10.1016/j.cmet.2023.10.002

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    sciencedirect.com/science/article/pii/S1550413123003716
  155. www.sciencedirect.com www.sciencedirect.com
    Differential DNA damage repair and PARP inhibitor vulnerability of the mammary epithelial lineages
    1
    1. scibot 28 Oct 2023
      JAX:5557

      DOI: 10.1016/j.celrep.2023.113256

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    sciencedirect.com/science/article/pii/S2211124723012688
  156. 52.53.155.43 52.53.155.43
    The T766M-EGFR lung cancer mutation promotes tumor growth by exploiting newfound assembly mechanisms in ligand-free EGFR oligomers
    1
    1. scibot 14 Oct 2023
      RRID:IMSR_JAX:00

      DOI: 10.1101/2023.06.16.545259

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    52.53.155.43/e45e39aa6be90d4518c1365e2458466145a6420b/2023.06.16.545259v2.full-html.html
  157. www.sciencedirect.com www.sciencedirect.com
    Genetic and pharmaceutical targeting of HIF1α allows combo-immunotherapy to boost graft vs. leukemia without exacerbation graft vs. host disease
    1
    1. scibot 13 Oct 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.xcrm.2023.101236

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    sciencedirect.com/science/article/pii/S2666379123004135
  158. www.biorxiv.org www.biorxiv.org
    Long-term engraftment of adult hematopoietic progenitors in a novel model of humanized mice
    1
    1. scibot 13 Oct 2023
      JAX:005557

      DOI: 10.1101/2023.10.02.560534

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    biorxiv.org/content/10.1101/2023.10.02.560534v1
  159. www.sciencedirect.com www.sciencedirect.com
    Cooperative CAR targeting to selectively eliminate AML and minimize escape
    1
    1. scibot 13 Oct 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.ccell.2023.09.010

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    sciencedirect.com/science/article/pii/S1535610823003264
  160. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nuclear speckles regulate HIF-2α programs and correlate with patient survival in kidney cancer
    1
    1. scibot 05 Oct 2023
      Jackson Laboratories, Strain #:005557

      DOI: 10.1101/2023.09.14.557228

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    ncbi.nlm.nih.gov/pmc/articles/PMC10515914/
  161. Sep 2023
  162. www.sciencedirect.com www.sciencedirect.com
    Signaling-induced systematic repression of miRNAs uncovers cancer vulnerabilities and targeted therapy sensitivity
    1
    1. scibot 30 Sep 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.xcrm.2023.101200

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    sciencedirect.com/science/article/pii/S2666379123003671
  163. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Myeloid leukemia vulnerabilities embedded in long noncoding RNA locus MYNRL15
    2
    1. scibot 29 Sep 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.isci.2023.107844

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    2. scibot 29 Sep 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.isci.2023.107844

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    ncbi.nlm.nih.gov/pmc/articles/PMC10520325/
  164. www.sciencedirect.com www.sciencedirect.com
    Modular pooled discovery of synthetic knockin sequences to program durable cell therapies
    1
    1. scibot 16 Sep 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.cell.2023.08.013

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    sciencedirect.com/science/article/pii/S0092867423009029
  165. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mouse intraductal modeling of primary ductal carcinoma in situ
    1
    1. scibot 08 Sep 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.xpro.2023.102526

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    ncbi.nlm.nih.gov/pmc/articles/PMC10480770/
  166. link.springer.com link.springer.com
    59 th EASD Annual Meeting of the European Association for the Study of Diabetes
    1
    1. scibot 07 Sep 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1007/s00125-023-05969-6

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    link.springer.com/article/10.1007/s00125-023-05969-6
  167. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Salmonella enterica serovar Typhi uses two type 3 secretion systems to replicate in human macrophages and colonize humanized mice
    1
    1. scibot 07 Sep 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1128/mbio.01137-23

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    ncbi.nlm.nih.gov/pmc/articles/PMC10470537/
  168. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Low-dose carboplatin modifies the tumor microenvironment to augment CAR T cell efficacy in human prostate cancer models
    1
    1. scibot 06 Sep 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1038/s41467-023-40852-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC10475084/
  169. Aug 2023
  170. www.sciencedirect.com www.sciencedirect.com
    Defining the identity and the niches of epithelial stem cells with highly pleiotropic multilineage potency in the human thymus
    1
    1. scibot 31 Aug 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.devcel.2023.08.017

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  171. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The circadian clock circuitry modulates leukemia initiating cell activity in T-cell acute lymphoblastic leukemia
    1
    1. scibot 31 Aug 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1186/s13046-023-02799-7

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    ncbi.nlm.nih.gov/pmc/articles/PMC10464343/
  172. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Skin-Grafting and Dendritic Cell “Boosted” Humanized Mouse Models Allow the Pre-Clinical Evaluation of Therapeutic Cancer Vaccines
    1
    1. scibot 29 Aug 2023
      RRID:IMSR_JAX:005557

      DOI: 10.3390/cells12162094

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    ncbi.nlm.nih.gov/pmc/articles/PMC10453599/
  173. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activating Inducible T cell Co-stimulator (ICOS) yields anti-tumor activity alone and in combination with anti-PD-1 checkpoint blockade
    3
    1. scibot 26 Aug 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1158/2767-9764.CRC-22-0293

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    2. scibot 26 Aug 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1158/2767-9764.CRC-22-0293

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    3. scibot 26 Aug 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1158/2767-9764.CRC-22-0293

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    ncbi.nlm.nih.gov/pmc/articles/PMC10430783/
  174. 52.53.155.43 52.53.155.43
    L858R emerges as a potential biomarker predicting response of lung cancer models to anti-EGFR antibodies: Comparison of osimertinib vs. cetuximab
    2
    1. scibot 18 Aug 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.xcrm.2023.101142

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    2. scibot 10 Aug 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.xcrm.2023.101142

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    52.53.155.43/bb31ad2b14838f5cede2aca897c595e2febf2f88/PIIS2666379123002951-html.html
  175. 52.53.155.43 52.53.155.43
    SOCS3 deletion in effector T cells confers an anti-tumorigenic role of IL-6 to the pro-tumorigenic cytokine
    2
    1. scibot 17 Aug 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.celrep.2023.112940

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    2. scibot 16 Aug 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.celrep.2023.112940

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    52.53.155.43/746dceaaaecd8ad8008d9df523b985f7a77f181a/PIIS2211124723009518-html.html
  176. 52.53.155.43 52.53.155.43
    crc-22-0293-html.html
    2
    1. scibot 11 Aug 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1158/2767-9764.crc-22-0293

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    2. scibot 11 Aug 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1158/2767-9764.crc-22-0293

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  177. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Effectors Enabling Adaptation to Mitochondrial Complex I Loss in Hürthle Cell Carcinoma
    1
    1. scibot 10 Aug 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1158/2159-8290.CD-22-0976

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    ncbi.nlm.nih.gov/pmc/articles/PMC10401073/
  178. www.sciencedirect.com www.sciencedirect.com
    Mammalian SWI/SNF chromatin remodeling complexes promote tyrosine kinase inhibitor resistance in EGFR-mutant lung cancer
    1
    1. scibot 04 Aug 2023
      JAX:005557

      DOI: 10.1016/j.ccell.2023.07.005

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    sciencedirect.com/science/article/pii/S1535610823002453
  179. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proteasome Inhibition Sensitizes Liposarcoma to MDM2 Inhibition with Nutlin-3 by Activating the ATF4/CHOP Stress Response Pathway
    1
    1. scibot 03 Aug 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1158/0008-5472.CAN-22-3173

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    ncbi.nlm.nih.gov/pmc/articles/PMC10391328/
  180. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BET Inhibitors Target the SCLC-N subtype of Small Cell Lung Cancer by Blocking NEUROD1 Transactivation
    1
    1. scibot 02 Aug 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1158/1541-7786.MCR-22-0594

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    ncbi.nlm.nih.gov/pmc/articles/PMC9898120/
  181. Jul 2023
  182. www.science.org www.science.org
    Targeting the chromatin effector Pygo2 promotes cytotoxic T cell responses and overcomes immunotherapy resistance in prostate cancer
    1
    1. scibot 14 Jul 2023
      JAX:005557

      DOI: 10.1126/sciimmunol.ade4656

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    science.org/doi/10.1126/sciimmunol.ade4656
  183. www.sciencedirect.com www.sciencedirect.com
    Co-targeting RANK pathway treats and prevents acquired resistance to CDK4/6 inhibitors in luminal breast cancer
    1
    1. scibot 14 Jul 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.xcrm.2023.101120

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    sciencedirect.com/science/article/pii/S2666379123002483
  184. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Extracellular Vesicle Secretion by Leukemia Cells In Vivo Promotes CLL Progression by Hampering Antitumor T-cell Responses
    1
    1. scibot 08 Jul 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1158/2643-3230.BCD-22-0029

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  185. 52.53.155.43 52.53.155.43
    can-22-3173-html.html
    1
    1. scibot 08 Jul 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1158/0008-5472.can-22-3173

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  186. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IGF1R inhibition enhances the therapeutic effects of Gq/11 inhibition in metastatic uveal melanoma progression
    1
    1. scibot 06 Jul 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1158/1535-7163.MCT-22-0147

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    ncbi.nlm.nih.gov/pmc/articles/PMC9812929/
  187. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    T-BET and EOMES sustain mature human NK cell identity and anti-tumor function
    1
    1. scibot 06 Jul 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1172/JCI162530

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  188. Jun 2023
  189. 52.53.155.43 52.53.155.43
    can-22-3173-html.html
    1
    1. scibot 30 Jun 2023
      RRID:IMSR_JAX:005557

      DOI: 10.1158/0008-5472.CAN-22-3173

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  190. 52.53.155.43 52.53.155.43
    can-22-2712-html.html
    1
    1. scibot 29 Jun 2023
      JAX:005557

      DOI: 10.1158/0008-5472.can-22-2712

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    52.53.155.43/726555d37fadfa1ef429cf94df3437d3f13c8b94/can-22-2712-html.html
  191. www.sciencedirect.com www.sciencedirect.com
    QKI shuttles internal m7G-modified transcripts into stress granules and modulates mRNA metabolism
    1
    1. scibot 28 Jun 2023
      RRID: IMSR_JAX:005557

      DOI: 10.1016/j.cell.2023.05.047

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  192. currentprotocols.onlinelibrary.wiley.com currentprotocols.onlinelibrary.wiley.com
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  193. 52.53.155.43 52.53.155.43
    ZIC1 dictates osteogenesis versus adipogenesis in human mesenchymal progenitor cells via a Hedgehog dependent mechanism
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  194. www.sciencedirect.com www.sciencedirect.com
    Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways
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    CNK2 promotes cancer cell motility by mediating ARF6 activation downstream of AXL signalling
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  196. www.biorxiv.org www.biorxiv.org
    RNA Helicase DDX3 Regulates RAD51 Localization and DNA Damage Repair in Ewing Sarcoma
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      DOI: 10.1101/2023.06.10.544474

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    Preclinical Efficacy of the Antibody–Drug Conjugate CLDN6–23-ADC for the Treatment of CLDN6-Positive Solid Tumors
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      DOI: 10.1158/1078-0432.CCR-22-2981

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