1,063 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dual targeting of AMRC12 and Malassezia globosa disrupts MYC liquid condensates-driven nuclear pore complex biogenesis in neuroblastoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12775802/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SynVectorDB: embedding-based retrieval system for synthetic biology parts
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    pmc.ncbi.nlm.nih.gov/articles/PMC12805114/
  4. Jan 2026
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Functionally coupled ion channels begin co-assembling at the start of their synthesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12807452/
  6. Nov 2025
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    R103 and R115 Affinity Mutants of ATeam ATP Biosensors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12527034/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Manipulation with Mutational Status of VHL Regulates Hypoxic Metabolism and Pro-Angiogenic Phenotypes in ccRCC Caki-1 Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12608846/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Why implementation gaps could undermine synthetic nucleic acid oversight
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    pmc.ncbi.nlm.nih.gov/articles/PMC12602429/
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibition of acn-1 , an ACE ortholog, reduces intestinal GST-4 expression in Caenorhabditis elegans
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    pmc.ncbi.nlm.nih.gov/articles/PMC12550603/
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cytoplasmic sequestering of a fungal stress-activated MAPK in response to a host plant phenolic acid
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    pmc.ncbi.nlm.nih.gov/articles/PMC12585099/
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Nano-size tantalum particles suppress the osteogenic activity of osteoblasts and stimulate osteoclasts
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    pmc.ncbi.nlm.nih.gov/articles/PMC12577323/
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ARFGAP1 serves as a critical host factor during E30 infection: QS11 inhibits viral pathogenesis in hFcRn-IFNAR−/− mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC12573814/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FGF10 ameliorates epileptic seizures and related cognitive dysfunction via the FGFR2/CALB1 signaling pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC12538785/
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cholesterol oxidase treatment impairs CXCR4-mediated T cell migration
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    pmc.ncbi.nlm.nih.gov/articles/PMC12532918/
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    S100A9 regulates eosinophil extracellular trap and activates NF-κB signaling in endometrial cancer: a machine learning-based biomarker discovery
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    pmc.ncbi.nlm.nih.gov/articles/PMC12639692/
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Biosynthesis of tauro-ursodeoxycholic acid (TUDCA) in Saccharomyces cerevisiae
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    pmc.ncbi.nlm.nih.gov/articles/PMC12492934/
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PIM3-mediated phosphorylation stabilizes myeloid leukemia factor 2 to promote metastasis in osteosarcoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12520695/
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Structural basis of T-loop-independent recognition and activation of CDKs by the CDK-activating kinase
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    pmc.ncbi.nlm.nih.gov/articles/PMC7618291/
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NAD+ reverses Alzheimer’s neurological deficits via regulating differential alternative RNA splicing of EVA1C
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    pmc.ncbi.nlm.nih.gov/articles/PMC12594206/
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Enhancing cross-organelle coordination to advance plant cytochrome P450 functionality in yeast
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    pmc.ncbi.nlm.nih.gov/articles/PMC12551693/
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Functional landscape of mechanistic diversity in 27 claudin family members at tight junctions
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    pmc.ncbi.nlm.nih.gov/articles/PMC12577684/
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mutational scanning of TnpB reveals latent activity for genome editing
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    pmc.ncbi.nlm.nih.gov/articles/PMC11844463/
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    GRASP: a modular toolkit for building synthetic pentatricopeptide repeat RNA-binding proteins
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    pmc.ncbi.nlm.nih.gov/articles/PMC12604669/
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    EFCAB10 anchors AK8 to the radial spoke for proper ciliary motility
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    pmc.ncbi.nlm.nih.gov/articles/PMC12541429/
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Homology-mediated transformation of frog-killing fungus Batrachochytrium dendrobatidis illuminates chytrid development and pathogenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12595416/
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Synaptobrevin-2 disease variants reveal spatial constraints within the presynaptic active zone
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    pmc.ncbi.nlm.nih.gov/articles/PMC12595502/
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Self-organization of cellulose-producing microbial communities during biofilm spreading
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    pmc.ncbi.nlm.nih.gov/articles/PMC12576783/
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Optogenetic induction of subcellular Ca2+ events in megakaryocytes and platelets using a highly Ca2+-conductive channelrhodopsin
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    pmc.ncbi.nlm.nih.gov/articles/PMC12504666/
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TNAP dephosphorylates phosphocholine and phosphoethanolamine and participates in triglyceride transport from the liver to the bloodstream
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    pmc.ncbi.nlm.nih.gov/articles/PMC12559424/
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Subtractive proteomic analysis to identify highly antigenic proteins and reverse vaccinology based novel vaccine development against Haemophillius parainfluenzae
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    pmc.ncbi.nlm.nih.gov/articles/PMC12612167/
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The genetically encoded biosensor FEOX is a molecular gauge for cellular iron environment dynamics at single cell resolution
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    pmc.ncbi.nlm.nih.gov/articles/PMC12541023/
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Assessing species-specific neonicotinoid toxicity using cross-species chimeric nicotinic acetylcholine receptors in a Drosophila model
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    pmc.ncbi.nlm.nih.gov/articles/PMC12533226/
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Structural insights into the mechanism of activation and inhibition of the prostaglandin D2 receptor 1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12508460/
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The inner nuclear membrane protein LEMD3 organizes the 3D chromatin architecture to maintain vascular smooth muscle cell identity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12495022/
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Nutrient stress diverts RRN3 from rRNA transcription to alternative polyadenylation of autophagy mRNAs in ovarian cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12638823/
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Construction of a Mycobacterium smegmatis Promoter Library for Therapeutic and Environmental Applications
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    pmc.ncbi.nlm.nih.gov/articles/PMC12529400/
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Efficient Agrobacterium‐Mediated Transformation of Green Arabidopsis Suspension Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12550646/
  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ABCC4 impairs the clearance of plasma LDL cholesterol through suppressing LDLR expression in the liver
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    pmc.ncbi.nlm.nih.gov/articles/PMC12491593/
  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of Fanconi anemia proteins causes a reliance on lysosomal exocytosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12586712/
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TPL2 Promotes Gastric Cancer Progression and Chemoresistance Through a Hypoxia-Induced Positive Feedback Loop with PPARδ
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    pmc.ncbi.nlm.nih.gov/articles/PMC12509916/
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    HDAC4/MybL1/YAP novel signaling axis is required for pancreatic cancer metastasis to the liver
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    pmc.ncbi.nlm.nih.gov/articles/PMC12631223/
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Prognostic value of M2 macrophage-related genes and their importance in the immunotherapy response in hepatocellular carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12489720/
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genome-Wide Analysis of Terpene Synthase Genes in Crocus sativus Reveals Their Regulatory Roles in Terpenoid Biosynthesis and Abiotic Stress Tolerance
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    pmc.ncbi.nlm.nih.gov/articles/PMC12524938/
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Derivation of Genetically Defined Murine Hepatoblastoma Cell Lines with Angiogenic Potential
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    pmc.ncbi.nlm.nih.gov/articles/PMC12468702/
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Vimentin immunization induces TH2/TH17 cell activation and autoantibody production in a novel mouse model of bleomycin induced systemic sclerosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12634585/
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Rational design of an epitope-centric vaccine against Pseudomonas aeruginosa using pangenomic insights and immunoinformatics approach
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    pmc.ncbi.nlm.nih.gov/articles/PMC12434008/
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Lactobacillus amylovorus KU4 inhibits adipocyte senescence in aged mice through necdin regulation of p53 activity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12517307/
  49. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Expansion of lysosomal capacity in early adult neurons driven by TFEB/HLH-30 protects dendrite maintenance during aging in Caenorhabditis elegans
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    pmc.ncbi.nlm.nih.gov/articles/PMC12510649/
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CLOCK-mediated acetylation of NF-κB p65 drives immune evasion in breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12632107/
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Glutamine synthetase shields triple-negative breast cancer cells from ferroptosis in metastasis triggered by glutamine deprivation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12465765/
  52. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    B7-H3 nanobody-based CAR T cells control multiple myeloma growth, while dual BCMA/B7-H3 CAR T cells overcome antigen escape
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    pmc.ncbi.nlm.nih.gov/articles/PMC12619266/
  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Functional mapping of epigenomic regulators uncovers coordinated tumor suppression by the HBO1 and MLL1 complexes
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    pmc.ncbi.nlm.nih.gov/articles/PMC12469823/
  54. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FADD Activation in Hepatocellular Carcinoma Potentiates CD8+T Cell Responses and Sensitizes to Immune Checkpoint Inhibitors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12434399/
  55. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    IL-4 downregulates gap junction protein connexin 26 to promote HIV-1 infection in macrophages
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    pmc.ncbi.nlm.nih.gov/articles/PMC12607889/
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Replication-competent adenovirus reporters utilizing endogenous viral expression architecture
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    pmc.ncbi.nlm.nih.gov/articles/PMC12548470/
  57. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cytoplasmic translocation of tripartite motif-containing 28 is critical for PRRSV-induced autophagy through promoting Vps34-Beclin1 complex formation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12548422/
  58. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of PTDSS1 in tumor cells improves immunogenicity and response to anti–PD-1 therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12422196/
  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Engineering Inducible Cell Fate Transitions by Harnessing Epigenetic Silencing
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    pmc.ncbi.nlm.nih.gov/articles/PMC12621680/
  60. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PIP4K attenuates PIP5K lipid kinase activity by disrupting membrane-mediated dimerization
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    pmc.ncbi.nlm.nih.gov/articles/PMC12485675/
  61. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRISPR/Cas9 screenings reveal the role of STX1A and CDK1 in Cathepsin G entering and killing colorectal cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12485829/
  62. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Engineering Spatial Control of Bacterial Organelles
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    pmc.ncbi.nlm.nih.gov/articles/PMC12485843/
  63. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    COPI-dependent intra-Golgi recycling at an intermediate stage of cisternal maturation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12458367/
  64. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Deep Receptor Scanning Reveals General Sequence Constraints on GPCR Biosynthesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12458215/
  65. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sequence-Independent RNA Sensing in Living Mammalian Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12458216/
  66. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    L1 insertion intermediates recombine with one another or with DNA breaks to form genome rearrangements
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    pmc.ncbi.nlm.nih.gov/articles/PMC12458204/
  67. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neuron type-specific mRNA translation programs provide a gateway for memory consolidation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12424637/
  68. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The ethylene response factor ERF1A regulates UV-C-induced delayed ripening in peach fruit
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    pmc.ncbi.nlm.nih.gov/articles/PMC12501976/
  69. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    DDX6 interacts with DDX3X to repress translation in microRNA-mediated silencing
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    pmc.ncbi.nlm.nih.gov/articles/PMC12418388/
  70. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PILS-Nir1 is a sensitive phosphatidic acid biosensor that reveals mechanisms of lipid production
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    pmc.ncbi.nlm.nih.gov/articles/PMC12419160/
  71. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Molecular characterization of four Helicobacter cetorum strains from dolphins compared to human Helicobacter pylori
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    pmc.ncbi.nlm.nih.gov/articles/PMC12477871/
  72. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Biliverdin reductase A is a major determinant of protective NRF2 signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12519219/
  73. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    De novo talin-1 variant L353F connects multifaceted clinical symptoms to alterations in talin-1 function
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    pmc.ncbi.nlm.nih.gov/articles/PMC12599238/
  74. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Bacterial cell widening alters periplasmic size and activates envelope stress responses
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    pmc.ncbi.nlm.nih.gov/articles/PMC12528386/
  75. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Predicting drug inactivation by changes in bacterial growth dynamics
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    pmc.ncbi.nlm.nih.gov/articles/PMC12420825/
  76. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TRAP seq in 3D angiogenesis assays reveals a distinct endothelial translatome associated with early and late stages of morphogenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12480577/
  77. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    LY6H is a marker of human pancreatic delta cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12474887/
  78. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Engineered prime editors with minimal genomic errors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12571883/
  79. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Microtubule architecture connects AMOT stability to YAP/TAZ mechanotransduction and Hippo signalling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12527920/
  80. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TRIM39-mediated deubiquitination upregulates RNF168 to evade autophagy-ferroptosis in triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12488878/
  81. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Hippocampal-cortical interactions in the consolidation of social memory
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    pmc.ncbi.nlm.nih.gov/articles/PMC12485024/
  82. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Calmodulin binding is required for calcium mediated TRPA1 desensitization
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    pmc.ncbi.nlm.nih.gov/articles/PMC12485084/
  83. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Structural basis for ligand promiscuity and high signaling activity of Kaposi’s Sarcoma-associated Herpesvirus-encoded GPCR
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    pmc.ncbi.nlm.nih.gov/articles/PMC12462484/
  84. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The DNA replication machinery transmits dual signals to prevent unscheduled licensing and execution of centrosome duplication
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    pmc.ncbi.nlm.nih.gov/articles/PMC12417547/
  85. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Stabilizing a Native Fold of Alpha-Synuclein with Short Helix-Constrained Peptides
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    pmc.ncbi.nlm.nih.gov/articles/PMC12458024/
  86. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Facile Synthesis of Lecithin-Sophorolipid Liponiosomes Encapsulating SARS-CoV‑2 Proteins for Therapeutic Applications
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    pmc.ncbi.nlm.nih.gov/articles/PMC12509005/
  87. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Novel p53 reactivators that are synergistic with olaparib for the treatment of gynecologic cancers with mutant p53
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  88. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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  89. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Fmp45 promotes Rad53 dephosphorylation via Ptc2 interaction to attenuate checkpoint signaling and maintain genome stability
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  90. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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  91. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Receptor activity–modifying protein 3 enhances GLP-1-mediated insulin secretion
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  92. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Proton First: Rationalizing a Proton Transfer in a Protein‐Fragment Complex
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  93. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibitory Effect of S0859 on the Antioxidant Master Switch Nuclear Factor Erythroid 2-Related Factor 2 in Lung Cancer Cells
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  94. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Multi-chassis expression of cyanobacterial and other bacterial biosynthetic gene clusters
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  95. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Disrupted glycosylphosphatidylinositol anchoring induces ER stress and restricts enterovirus infection
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  96. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Human disease variants of KATNIP fail to support CILK1 activation and control of primary cilia
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  97. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A modular high-throughput approach for advancing synthetic biology in the chloroplast of Chlamydomonas
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  98. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Serotonin 5-HT2C Receptor Signaling Analysis Reveals Psychedelic Biased Agonism
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  99. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    AGAPIR: A Novel PIWI‐Interacting RNA Enhancing Post‐Decompression Angiogenesis in Degenerative Cervical Myelopathy
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  100. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRISPR/Cas9-compatible plasmids enabling seven dominant genetic selection methods for the human fungal pathogen Cryptococcus neoformans
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  101. Sep 2025
  102. www.biorxiv.org www.biorxiv.org
    Novel monoclonal antibodies against the C-terminal HEAT domain of Huntingtin
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  103. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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  104. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Gibberellin transport affects lateral root growth through HY5 in response to far-red light
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  105. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A single component landing site for efficient transgenesis using recombination-mediated insertion
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  106. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Stimulus-Dependent Expression of Bdnf Is Mediated by ATF2, MYT1L, and EGR1 Transcription Factors
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  107. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Characterization of an isobutylene epoxide hydrolase (IbcK) from the isobutylene-catabolizing bacterium Mycolicibacterium sp. ELW1
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  108. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Runaway evolution of telomeres in ascomycetous yeasts was accompanied by the replacement of ancestral telomeric proteins
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  109. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    In vivo pathway optimization in yeast via loxpsym-mediated shuffling of upstream activating sequences
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  110. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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  111. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ints7 deficiency activates DNA damage response to elicit resurgence of endogenous retrovirus MERVL and anastasis of embryonic stem cells
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  112. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ERRα Knockout Promotes M2 Microglial Polarization and Inhibits Ferroptosis in Sepsis-Associated Brain Dysfunction
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  113. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    DNAJ Homolog Subfamily C Member 11 Stabilizes SARS-CoV-2 NSP3 to Promote Double-Membrane Vesicle Formation
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  114. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Therapeutic pCRISPRi Delivery to Lung Squamous Cell Carcinoma by Combining Nanobubbles and Ultrasound
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  115. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Broad-spectrum antitumor analysis of the telomerase activity inhibitor TPCH derived from the human constitutively expressed protein LPTS/PinX1
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  116. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Endogenous ligands of bovine FFAR2/GPR43 display distinct pharmacological properties
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  117. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    KFERQ-selective protein autophagy in Caenorhabditis elegans depends on LMP-1
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  118. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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  119. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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  120. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Deep tissue profiling of Populus stem at single nucleus level reveals uncharacterized cell types and cell-specific gene regulatory networks
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  121. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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  122. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Pan-RAS Inhibitor with a Unique Mechanism of Action Blocks Tumor Growth and Induces Antitumor Immunity in Gastrointestinal Cancer
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  123. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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  124. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Clustering within a single-component biomolecular condensate
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  125. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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  126. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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  127. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting ALDH16A1 mediated thioredoxin lysosomal degradation to enhance ferroptosis susceptibility in SMARCA4-deficient NSCLC
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  128. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Phytochrome B and phytochrome-interacting-factor4 modulate tree seasonal growth in cold environments
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  129. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Phosphorylation toggles the SARS-CoV-2 nucleocapsid protein between two membrane-associated condensate states
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  130. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeted inhibition of macrophage STING signaling alleviates inflammatory injury and ventricular remodeling in acute myocardial infarction
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  131. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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  132. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    DNMT1 recruits RUNX1 and represses FOXO1 transcription to inhibit anti-inflammatory activity of regulatory T cells and augments sepsis-induced lung injury
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  133. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Harmonizing TREC Thresholds in Newborn Screening for SCID: Insights From Russian Validation Cohort
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  134. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRISPR/Cas9 screening identifies SUV39H2 as a key regulator of oHSV-1 resistance in oral squamous cell carcinoma
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  135. Aug 2025
  136. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Renin–Angiotensin System Modulates SARS-CoV-2 Entry via ACE2 Receptor
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  137. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Structure-Based Design of Small-Molecule Inhibitors of Human Interleukin-6
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  138. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Valproic Acid Enhances the Anticancer Effect of L-Ascorbic Acid by Upregulating Sodium-Dependent Vitamin C Transporter 2 in Colorectal Cancer
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  139. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SDR42E1 modulates vitamin D absorption and cancer pathogenesis: insights from an in vitro model
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  140. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    USP13 Suppresses Colorectal Cancer Angiogenesis by Downregulating VEGFA Expression through Inhibition of the PTEN-AKT Pathway
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  141. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting NOTCH1-KEAP1 axis retards chronic liver injury and liver cancer progression via regulating stabilization of NRF2
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  142. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pyruvate kinase M2 activation maintains mitochondrial metabolism by regulating the interaction between HIF-1α and PGC-1α in diabetic kidney disease
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  143. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sleep need-dependent plasticity of a thalamic circuit promotes homeostatic recovery sleep
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  144. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Knocking out of the Mitochondrial Gene orf218 Using mitoTALECD Restores Cytoplasmic Male Sterility in Eggplant
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  145. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Opposing roles for lipocalins and a CD36 family scavenger receptor in apical extracellular matrix-dependent protection of narrow tube integrity
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  146. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Oscillatory signal decoding within the ERK cascade
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  147. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Bioelectrochemical Crossbar Architecture Screening Platform (BiCASP) for Extracellular Electron Transfer
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  148. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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  149. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A comprehensive model of tomato fruit ripening regulation by the transcription factors NOR-like1, NAC-NOR, and MADS-RIN
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  150. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The function of MYC in base excision repair protects against RAS-induced senescence
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  151. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification of cognate recombination directionality factors for large serine recombinases by virtual pulldown
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  152. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The dual ubiquitin binding mode of SPRTN secures rapid spatiotemporal proteolysis of DNA–protein crosslinks
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  153. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TET dioxygenases localize at splicing speckles and promote RNA splicing
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  154. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    C-terminal tagging impairs AGO2 function
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  155. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Molecular mechanism of ligand recognition and activation of lysophosphatidic acid receptor LPAR6
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  156. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Transdifferentiation of tongue muscle cells into cancer-associated fibroblasts in response to tongue squamous cell carcinoma
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  157. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Glial reactivity and cognitive decline follow chronic heterochromatin loss in neurons
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  158. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RIPK1 S213E mutant suppresses RIPK1-dependent cell death by preventing interactions with RIPK3 and CASP8
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  159. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The impact of ERUPR on mitochondrial integrity mediated by PDK4
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  160. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Engineered Marine Biofilms for Ocean Environment Monitoring
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  161. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Protocol for directed differentiation of human induced pluripotent stem cells into thyroid follicular epithelial cells
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  162. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Immune targeting of triple-negative breast cancer through a clinically actionable STING agonist-CAR T cell platform
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  163. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The yeast optogenetic toolkit (yOTK) for spatiotemporal control of gene expression in budding yeast
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    pmc.ncbi.nlm.nih.gov/articles/PMC12288673/
  164. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Non-cognate ligands of hepatitis C virus envelope broadly neutralizing antibodies induce virus-neutralizing sera in mice
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  165. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SMAD3 orchestrates RNF167 and STAMBPL1-mediated Sestrin2 ubiquitination to drive gastric cancer progression
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  166. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mutation of PUB21 in tomato leads to reduced susceptibility to necrotrophic fungi
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  167. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dynamic and Biphasic Regulation of Cell Migration by Ras
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  168. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Broad-spectrum tolerance to disinfectant-mediated bacterial killing due to mutation of the PheS aminoacyl tRNA synthetase
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  169. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification of a fungal antibacterial endopeptidase that cleaves peptidoglycan
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  170. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Evaluating protein complexes between human aquaporin and calmodulin using biomolecular fluorescence complementation
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  171. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Programmable protein ligation on cell surfaces
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  172. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Unveiling the Frontiers of Synthetic Biology in Brazil: Pioneering the National Synthetic Biology Network
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  173. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Computationally Designed Peroxygenases That Exhibit Diverse and Selective Terpene Oxyfunctionalization
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  174. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibition of TFF3 improves the infiltration and function of CD8+ T cells by downregulating the expression of PD-L1 in colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12325462/
  175. Jul 2025
  176. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MyD88 polymerization and association to cellular membranes in a yeast heterologous model
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    pmc.ncbi.nlm.nih.gov/articles/PMC12297185/
  177. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Arabidopsis CNL receptor SUT1 confers immunity in hydathodes against the vascular pathogen Xanthomonas campestris pv. campestris
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    pmc.ncbi.nlm.nih.gov/articles/PMC12233906/
  178. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    In planta complementation of the betalain biosynthetic pathway with a bacterial dioxygenase
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    pmc.ncbi.nlm.nih.gov/articles/PMC12186922/
  179. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Human endogenous retrovirus-K envelope protein is aberrantly expressed in serous ovarian cancer and promotes chemosensitivity via NF-κB/P-glycoprotein pathway inhibition
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    pmc.ncbi.nlm.nih.gov/articles/PMC12232173/
  180. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification of EppR, a Second Repressor of Error‐Prone DNA Polymerase Genes in Acinetobacter baumannii
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    pmc.ncbi.nlm.nih.gov/articles/PMC12242105/
  181. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Crystal structure analysis of oxygen-induced degradation occurring in rsCherry
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    pmc.ncbi.nlm.nih.gov/articles/PMC12210193/
  182. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    High-throughput metabolic engineering of Yarrowia lipolytica through gene expression tuning
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    pmc.ncbi.nlm.nih.gov/articles/PMC12168020/
  183. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Fungal evasion of Drosophila immunity involves blocking the cathepsin-mediated cleavage maturation of the danger-sensing protease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11760918/
  184. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A genome-wide CRISPR screen unveils the endosomal maturation protein WDR91 as a promoter of productive ASO activity in melanoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12169777/
  185. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Exploring the oncogenic impact of heteroplasmic de novo MT-ND5 truncating mutations
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    pmc.ncbi.nlm.nih.gov/articles/PMC12266708/
  186. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Multiple Mechanisms of HIV-1 Resistance to PGT135 in a Chinese Subtype B’ Slow Progressor
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    pmc.ncbi.nlm.nih.gov/articles/PMC12196039/
  187. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Spindle Orientation Regulation Is Governed by Redundant Cortical Mechanosensing and Shape-Sensing Mechanisms
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    pmc.ncbi.nlm.nih.gov/articles/PMC12193269/
  188. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PTEN in somatostatin neurons regulates fear and anxiety and is required for inhibitory synaptic connectivity within central amygdala
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    pmc.ncbi.nlm.nih.gov/articles/PMC12240933/
  189. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    “Open science” meets commercial realities: a qualitative study of factors influencing sharing in synthetic biology research in Australia
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    pmc.ncbi.nlm.nih.gov/articles/PMC12170601/
  190. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tumoroid model recreates clinically relevant phenotypes of high grade serous ovarian cancer (HGSC) cells, carcinoma associated fibroblasts, and macrophages
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    pmc.ncbi.nlm.nih.gov/articles/PMC12204350/
  191. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting PCNA/AR interaction inhibits AR-mediated signaling in castration resistant prostate cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12219270/
  192. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Biochemical and structural characterization of the human gut microbiome metallopeptidase IgAse provides insight into its unique specificity for the F ab ’ region of IgA1 and IgA2
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    pmc.ncbi.nlm.nih.gov/articles/PMC12237041/
  193. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Correction of pathogenic mitochondrial DNA in patient-derived disease models using mitochondrial base editors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12186987/
  194. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Acute degradation of nucleolin reveals its novel functions in cell cycle progression and cell division in triple negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12257848/
  195. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Robo1 CAR-NK92 and radiotherapy exert synergistic efficacy in solid tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12218003/
  196. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    LncRNA H19 acts as a ceRNA to promote glioblastoma malignancy by sponging miR-19b-3p and upregulating SERPINE1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12177970/
  197. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Evaluating the predictive power of combined gene expression dynamics from single cells on antibiotic survival
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    pmc.ncbi.nlm.nih.gov/articles/PMC12172483/
  198. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRISPRi-mediated repression of three cI repressors induces the expression of three related Neisseria gonorrhoeae bacteriophages
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    pmc.ncbi.nlm.nih.gov/articles/PMC12186493/
  199. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sequestration of ribosome biogenesis factors in HSV-1 nuclear aggregates revealed by spatially resolved thermal profiling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12204162/
  200. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Striatal dopamine signals errors in prediction across different informational domains
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    pmc.ncbi.nlm.nih.gov/articles/PMC12239964/
  201. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Through the lens of bioenergy crops: advances, bottlenecks, and promises of plant engineering
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    pmc.ncbi.nlm.nih.gov/articles/PMC12270471/
  202. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ARID1A deficiency promotes malignant proliferation of hepatocellular carcinoma by activating HDAC7/ENO1 signaling pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC12180837/
  203. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Minimal shuttle vectors for Saccharomyces cerevisiae
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    pmc.ncbi.nlm.nih.gov/articles/PMC12224612/
  204. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Expanding genetic engineering capabilities in Vibrio natriegens with the Vnat Collection
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    pmc.ncbi.nlm.nih.gov/articles/PMC12255299/
  205. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Differential oligomerization regulates PHF13 chromatin affinity and function
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    pmc.ncbi.nlm.nih.gov/articles/PMC12214034/
  206. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Leveraging protein language models for cross-variant CRISPR/Cas9 sgRNA activity prediction
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    pmc.ncbi.nlm.nih.gov/articles/PMC12254127/