402 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PFKFB3-dependent redox homeostasis and DNA repair support cell survival under EGFR-TKIs in non-small cell lung carcinoma
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    1. scibot 22 Dec 2024
      RRID:SCR_005012

      DOI: 10.1186/s40170-024-00366-y

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    pmc.ncbi.nlm.nih.gov/articles/PMC11658331/
  3. biosignaling.biomedcentral.com biosignaling.biomedcentral.com
    CD69+CD103+CD8+ tissue-resident memory T cells possess stronger anti-tumor activity and predict better prognosis in colorectal cancer
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    1. scibot 21 Dec 2024
      RRID:SCR_005012

      DOI: 10.1186/s12964-024-01990-3

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  4. aacrjournals.org aacrjournals.org
    Large-Scale Comparative Analysis of Canine and Human Osteosarcomas Uncovers Conserved Clinically Relevant Tumor Microenvironment Subtypes
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    1. scibot 17 Dec 2024
      RRID:SCR_005012

      DOI: 10.1158/1078-0432.CCR-24-1854

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    aacrjournals.org/clincancerres/article/30/24/5630/750426/Large-Scale-Comparative-Analysis-of-Canine-and
  5. Dec 2024
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Delta-24-RGD, an oncolytic adenovirus, increases survival and promotes proinflammatory immune landscape remodeling in models of AT/RT and CNS-PNET
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    1. scibot 13 Dec 2024
      RRID:SCR_005012

      DOI: 10.1158/1078-0432.CCR-20-3313

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    pmc.ncbi.nlm.nih.gov/articles/PMC7617079/
  7. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Epigenetic Suppression of miR-137 Induces RNF4 Expression, Facilitating Wnt Signaling in Colorectal Cancer
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    1. scibot 13 Dec 2024
      RRID:SCR_005012

      DOI: 10.1002/mc.23859

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    onlinelibrary.wiley.com/doi/full/10.1002/mc.23859
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TCR-Engineered T Cells Directed against Ropporin-1 Constitute a Safe and Effective Treatment for Triple-Negative Breast Cancer
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    1. scibot 12 Dec 2024
      RRID:SCR_005012

      DOI: 10.1158/2159-8290.CD-24-0168

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    pmc.ncbi.nlm.nih.gov/articles/PMC11609630/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MYC Drives mRNA Pseudouridylation to Mitigate Proliferation-Induced Cellular Stress during Cancer Development
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    1. scibot 12 Dec 2024
      RRID:SCR_005012

      DOI: 10.1158/0008-5472.CAN-24-1102

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    pmc.ncbi.nlm.nih.gov/articles/PMC11609627/
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Capicua C1 Domain Is Required for Full Activity of the CIC::DUX4 Fusion Oncoprotein
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    1. scibot 11 Dec 2024
      RRID:SCR_005012

      DOI: 10.1158/2767-9764.CRC-24-0348

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  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Single-Cell Analysis of Bone Marrow CD8+ T Cells in Myeloid Neoplasms Reveals Pathways Associated with Disease Progression and Response to Treatment with Azacitidine
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    1. scibot 11 Dec 2024
      RRID:SCR_005012

      DOI: 10.1158/2767-9764.CRC-24-0310

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  12. Nov 2024
  13. www.sciencedirect.com www.sciencedirect.com
    Caspase-1 knockout disrupts pyroptosis and protects photoreceptor cells from photochemical damage
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    1. scibot 24 Nov 2024
      Gene Expression Omnibus database

      DOI: 10.1016/j.mcp.2024.101991

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    sciencedirect.com/science/article/pii/S0890850824000434
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting Catechol-O-Methyltransferase Induces Mitochondrial Dysfunction and Enhances the Efficacy of Radiotherapy in Glioma
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    1. scibot 08 Nov 2024
      RRID:SCR_005012

      DOI: 10.1158/0008-5472.CAN-24-0134

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  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Building a community-driven bioinformatics platform to facilitate Cannabis sativa multi-omics research
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    1. scibot 07 Nov 2024
      RRID:SCR_005012

      DOI: 10.46471/gigabyte.137

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  16. 52.53.155.43 52.53.155.43
    crc-24-0310-html.html
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    1. scibot 07 Nov 2024
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      DOI: 10.1158/2767-9764.crc-24-0310

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  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Omics-driven investigation of the biology underlying intrinsic submaximal working capacity and its trainability
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    1. scibot 07 Nov 2024
      RRID:SCR_005012

      DOI: 10.1152/physiolgenomics.00163.2022

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  18. Oct 2024
  19. aacrjournals.org aacrjournals.org
    NK Receptor Signaling Lowers TCR Activation Threshold, Enhancing Selective Recognition of Cancer Cells by TAA-Specific CTLs
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    1. scibot 08 Oct 2024
      RRID:SCR_005012

      DOI: 10.1158/2326-6066.CIR-24-0061

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    aacrjournals.org/cancerimmunolres/article/12/10/1421/748722/NK-Receptor-Signaling-Lowers-TCR-Activation
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Development of a polygenic score predicting drug resistance and patient outcome in breast cancer
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    1. scibot 05 Oct 2024
      RRID:SCR_005012

      DOI: 10.1038/s41698-024-00714-7

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    ncbi.nlm.nih.gov/pmc/articles/PMC11447244/
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SREBP-Dependent Regulation of Lipid Homeostasis Is Required for Progression and Growth of Pancreatic Ductal Adenocarcinoma
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    1. scibot 04 Oct 2024
      RRID:SCR_005012

      DOI: 10.1158/2767-9764.CRC-24-0120

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    ncbi.nlm.nih.gov/pmc/articles/PMC11444119/
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    Dual-hit strategy for therapeutic targeting of pancreatic cancer in patient-derived xenograft tumors
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    1. scibot 03 Oct 2024
      RRID:SCR_005012

      DOI: 10.1158/1078-0432.CCR-23-0131

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    2. scibot 03 Oct 2024
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      DOI: 10.1158/1078-0432.CCR-23-0131

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    ncbi.nlm.nih.gov/pmc/articles/PMC11019863/
  23. aacrjournals.org aacrjournals.org
    Clinical Outcome–Related Mutational Signatures Identified by Integrative Genomic Analysis in Nasopharyngeal Carcinoma
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    1. scibot 02 Oct 2024
      RRID:SCR_005012

      DOI: 10.1158/1078-0432.CCR-20-2854

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    aacrjournals.org/clincancerres/article/26/24/6494/82920/Clinical-Outcome-Related-Mutational-Signatures
  24. Sep 2024
  25. www.biorxiv.org www.biorxiv.org
    Protrusion force and cell-cell adhesion play a critical role in collective tumor cluster migration
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    1. scibot 27 Sep 2024
      RRID:SCR_005012

      DOI: 10.1101/2024.09.18.613706

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    biorxiv.org/content/10.1101/2024.09.18.613706v1
  26. www.tandfonline.com www.tandfonline.com
    Integrated Transcriptomics and Proteomics Identified CMPK1 as a Potential Biomarker for Type 2 Diabetes Mellitus
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      DOI: 10.2147/DMSO.S467950

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  27. www.sciencedirect.com www.sciencedirect.com
    β-chitosan attenuates hepatic macrophage-driven inflammation and reverses aging-related cognitive impairment
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      DOI: 10.1016/j.isci.2024.110766

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    sciencedirect.com/science/article/pii/S2589004224019916
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IL36G-producing neutrophil-like monocytes promote cachexia in cancer
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      DOI: 10.1038/s41467-024-51873-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC11393454/
  29. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Disruption of HSD17B12 in mouse hepatocytes leads to reduced body weight and defect in the lipid droplet expansion associated with microvesicular steatosis
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    1. scibot 13 Sep 2024
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      DOI: 10.1096/fj.202400333RR

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  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inferring Characteristics of the Tumor Immune Microenvironment of Patients with HNSCC from Single-Cell Transcriptomics of Peripheral Blood
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    1. scibot 12 Sep 2024
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      DOI: 10.1158/2767-9764.CRC-24-0092

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      DOI: 10.1158/2767-9764.CRC-24-0092

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  31. www.biorxiv.org www.biorxiv.org
    Phosphodiesterase 3 inhibitors boost bone outgrowth
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    1. scibot 12 Sep 2024
      Gene Expression Omnibus

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  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Apelin (APLN) is a biomarker contributing to the diagnosis and prognosis of hepatocellular carcinoma
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      DOI: 10.1038/s41598-024-71495-z

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    ncbi.nlm.nih.gov/pmc/articles/PMC11371925/
  33. www.sciencedirect.com www.sciencedirect.com
    SRSF3 suppresses RCC tumorigenesis and progression via regulating SP4 alternative splicing
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      DOI: 10.1016/j.bbamcr.2024.119841

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    sciencedirect.com/science/article/pii/S0167488924001848
  34. Aug 2024
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterizing Relationships between T-cell Inflammation and Outcomes in Patients with High-Risk Neuroblastoma According to Mesenchymal and Adrenergic Signatures
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    1. scibot 30 Aug 2024
      RRID:SCR_005012

      DOI: 10.1158/2767-9764.CRC-24-0214

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    ncbi.nlm.nih.gov/pmc/articles/PMC11350481/
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Normalization of Snai1-mediated vessel dysfunction increases drug response in cancer
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      DOI: 10.1038/s41388-024-03113-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC11347376/
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mast Cell Infiltration and Subtype Promote Malignant Transformation of Oral Precancer and Progression of Oral Cancer
    1
    1. scibot 27 Aug 2024
      RRID:SCR_005012

      DOI: 10.1158/2767-9764.CRC-24-0169

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    ncbi.nlm.nih.gov/pmc/articles/PMC11339667/
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cadmium activation of wild-type and constitutively active estrogen receptor alpha
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      DOI: 10.3389/fendo.2024.1380047

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    ncbi.nlm.nih.gov/pmc/articles/PMC11341946/
  39. www.sciencedirect.com www.sciencedirect.com
    TNFR1 signaling promotes pancreatic tumor growth by limiting dendritic cell number and function
    1
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      NCBI Gene Expression Omnibus

      DOI: 10.1016/j.xcrm.2024.101696

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    sciencedirect.com/science/article/pii/S2666379124004178
  40. www.sciencedirect.com www.sciencedirect.com
    Single-cell sequencing reveals that specnuezhenide protects against osteoporosis via activation of METTL3 in LEPR+ BMSCs
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      Gene Expression Omnibus

      DOI: 10.1016/j.ejphar.2024.176908

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    sciencedirect.com/science/article/pii/S0014299924005971
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A PDE3A-SLFN12 Molecular Glue Exhibits Significant Antitumor Activity in TKI-Resistant Gastrointestinal Stromal Tumors
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    1. scibot 22 Aug 2024
      RRID:SCR_005012

      DOI: 10.1158/1078-0432.CCR-24-0096

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    ncbi.nlm.nih.gov/pmc/articles/PMC11325149/
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Galectin-3 induces pathogenic immunosuppressive macrophages through interaction with TREM2 in lung cancer
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    1. scibot 22 Aug 2024
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      DOI: 10.1186/s13046-024-03124-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC11321020/
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrated Transcriptomics and Proteomics Identified CMPK1 as a Potential Biomarker for Type 2 Diabetes Mellitus
    1
    1. scibot 19 Aug 2024
      RRID:SCR_005012

      DOI: 10.2147/DMSO.S467950

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    ncbi.nlm.nih.gov/pmc/articles/PMC11299646/
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting heme degradation pathway augments prostate cancer cell sensitivity to docetaxel-induced apoptosis and attenuates migration
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    1. scibot 18 Aug 2024
      RRID:SCR_005012

      DOI: 10.3389/fonc.2024.1431362

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  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The BET PROTAC inhibitor GNE-987 displays anti-tumor effects by targeting super-enhancers regulated gene in osteosarcoma
    1
    1. scibot 18 Aug 2024
      RRID:SCR_005012

      DOI: 10.1186/s12885-024-12691-y

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  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anti-EGFR Antibody–Drug Conjugate Carrying an Inhibitor Targeting CDK Restricts Triple-Negative Breast Cancer Growth
    1
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      DOI: 10.1158/1078-0432.CCR-23-3110

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    ncbi.nlm.nih.gov/pmc/articles/PMC11292198/
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    p300 KAT Regulates SOX10 Stability and Function in Human Melanoma
    1
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  48. Jul 2024
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZNF397 Deficiency Triggers TET2-Driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer
    2
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    ncbi.nlm.nih.gov/pmc/articles/PMC11285331/
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma
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  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CAR T-cells targeting FGFR4 and CD276 simultaneously show potent antitumor effect against childhood rhabdomyosarcoma
    1
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      DOI: 10.1038/s41467-024-50251-x

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  52. www.sciencedirect.com www.sciencedirect.com
    Predictive Biomarkers for Response to TGF- β Inhibition in Resensitizing Chemo(radiated) Esophageal Adenocarcinoma
    1
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  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Drosophila model to study Retinitis pigmentosa pathology associated with mutations in the core splicing factor Prp8
    3
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      RRID:SCR_007303

      DOI: 10.1242/dmm.043174

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    ncbi.nlm.nih.gov/pmc/articles/PMC7328144/
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The methyltransferases METTL7A and METTL7B confer resistance to thiol-based histone deacetylase inhibitors
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  55. www.mdpi.com www.mdpi.com
    Immunological Signatures for Early Detection of Human Head and Neck Squamous Cell Carcinoma through RNA Transcriptome Analysis of Blood Platelets
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      DOI: 10.3390/cancers16132399

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  56. Jun 2024
  57. aacrjournals.org aacrjournals.org
    Obesogenic High-Fat Diet and MYC Cooperate to Promote Lactate Accumulation and Tumor Microenvironment Remodeling in Prostate Cancer
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      DOI: 10.1158/0008-5472.CAN-23-0519

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    aacrjournals.org/cancerres/article/84/11/1834/745520/Obesogenic-High-Fat-Diet-and-MYC-Cooperate-to
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Early Changes in Tumor-Naive Cell-Free Methylomes and Fragmentomes Predict Outcomes in Pembrolizumab-Treated Solid Tumors
    1
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      DOI: 10.1158/2159-8290.CD-23-1060

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  59. May 2024
  60. aacrjournals.org aacrjournals.org
    Preclinical evaluation of NTX-301, a Novel DNA Hypomethylating Agent in Ovarian Cancer
    2
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      RRID:SCR_005012

      DOI: 10.1158/1078-0432.CCR-23-2368

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    aacrjournals.org/clincancerres/article/30/6/1175/735023/Preclinical-Evaluation-of-NTX-301-a-Novel-DNA
  61. aacrjournals.org aacrjournals.org
    Development of chromosome 1q+ specific treatment for highest risk pediatric posterior fossa ependymoma
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      DOI: 10.1158/1078-0432.CCR-23-3156

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    aacrjournals.org/clincancerres/article/30/8/1544/742119/Development-of-Chromosome-1q-Specific-Treatment
  62. 52.53.155.43 52.53.155.43
    mcr-23-0295-html.html
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      DOI: 10.1158/1541-7786.mcr-23-0295

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  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmacologic Targeting of Histone H3K27 Acetylation/BRD4-dependent Induction of ALDH1A3 for Early-phase Drug Tolerance of Gastric Cancer
    1
    1. scibot 22 May 2024
      RRID:SCR_005012

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    ncbi.nlm.nih.gov/pmc/articles/PMC11104289/
  64. www.nature.com www.nature.com
    The genomic landscape of Vk*MYC myeloma highlights shared pathways of transformation between mice and humans
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      DOI: 10.1038/s41467-024-48091-w

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  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    De Novo Purine Metabolism is a Metabolic Vulnerability of Cancers with Low p16 Expression
    2
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      RRID:SCR_005012

      DOI: 10.1158/2767-9764.CRC-23-0450

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  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MILIP Binding to tRNAs Promotes Protein Synthesis to Drive Triple-Negative Breast Cancer
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      RRID:SCR_005012

      DOI: 10.1158/0008-5472.CAN-23-3046

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  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modeling Myeloma Dissemination In Vitro with hMSC-interacting Subpopulations of INA-6 Cells and Their Aggregation/Detachment Dynamics
    2
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      RRID:SCR_005012

      DOI: 10.1158/2767-9764.CRC-23-0411

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  68. Apr 2024
  69. aacrjournals.org aacrjournals.org
    Single-cell transcriptomics reveals pre-existing COVID-19 vulnerability factors in lung cancer patients
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      RRID:SCR_005012

      DOI: 10.1158/1541-7786.MCR-23-0692

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    aacrjournals.org/mcr/article/22/3/240/734706/Single-Cell-Transcriptomics-Reveals-Pre-existing
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ERBB3 overexpression is enriched in diverse patient populations with castration-sensitive prostate cancer and is associated with a unique AR activity signature
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      DOI: 10.1158/1078-0432.CCR-23-2161

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  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Optimization of a mouse model of pancreatic cancer to simulate the human phenotypes of metastasis and cachexia
    1
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      DOI: 10.1186/s12885-024-12104-0

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    ncbi.nlm.nih.gov/pmc/articles/PMC10993462/
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neutrophils Mediate Protection Against Colitis and Carcinogenesis by Controlling Bacterial Invasion and IL22 Production by γδ T Cells
    1
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      RRID:SCR_005012

      DOI: 10.1158/2326-6066.CIR-23-0295

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    ncbi.nlm.nih.gov/pmc/articles/PMC10985471/
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRMT1 sustains de novo fatty acid synthesis by methylating PHGDH to drive chemoresistance in triple-negative breast cancer
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      DOI: 10.1158/0008-5472.CAN-23-2266

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  74. Mar 2024
  75. www.nature.com www.nature.com
    Clinically-observed FOXA1 mutations upregulate SEMA3C through transcriptional derepression in prostate cancer
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      DOI: 10.1038/s41598-024-57854-w

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  76. www.sciencedirect.com www.sciencedirect.com
    Identification of a DNA-methylome-based signature for prognosis prediction in driver gene-negative lung adenocarcinoma
    1
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      DOI: 10.1016/j.canlet.2024.216835

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  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Xrp1 governs the stress response program to spliceosome dysfunction
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      DOI: 10.1093/nar/gkae055

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  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    N6-methyladenosine-associated genetic variants in NECTIN2 and HPCAL1 are risk factors for abdominal aortic aneurysm
    1
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      DOI: 10.1016/j.isci.2024.109419

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  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Novel HOXA10-Associated 5 Gene-Based Prognostic Signature for Stratification of Short-Term Survivors of Pancreatic Ductal Adenocarcinoma
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      DOI: 10.1158/1078-0432.CCR-23-0825

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  80. www.biorxiv.org www.biorxiv.org
    Lack of TGFβ signaling competency predicts conversion of immune poor cancer to immune rich and response to checkpoint blockade
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      DOI: 10.1101/2024.03.06.583752

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    biorxiv.org/content/10.1101/2024.03.06.583752v1
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    C17orf80 binds the mitochondrial genome to promote its replication
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      DOI: 10.1083/jcb.202302037

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  82. www.nature.com www.nature.com
    A cellular model provides insights into the pathogenicity of the oncogenic FOXL2 somatic variant p.Cys134Trp
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      DOI: 10.1038/s41416-024-02613-x

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  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modeling Molecular Pathogenesis of Idiopathic Pulmonary Fibrosis-Associated Lung Cancer in Mice
    1
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      DOI: 10.1158/1541-7786.MCR-23-0480

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    ncbi.nlm.nih.gov/pmc/articles/PMC10906012/
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    INX-315, a selective CDK2 inhibitor, induces cell cycle arrest and senescence in solid tumors
    1
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      DOI: 10.1158/2159-8290.CD-23-0954

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  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of a ΔNp63-Dependent Basal-Like A Subtype-Specific Transcribed Enhancer Program (B-STEP) in Aggressive Pancreatic Ductal Adenocarcinoma
    2
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  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cancer-associated fibroblast-specific expression of the matricellular protein CCN1 coordinates neovascularization and stroma deposition in melanoma metastasis
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  87. Feb 2024
  88. 52.53.155.43 52.53.155.43
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  89. aacrjournals.org aacrjournals.org
    Spatial transcriptomics suggests that alterations occur in the preneoplastic breast microenvironment of BRCA1/2 mutation carriers
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  90. aacrjournals.org aacrjournals.org
    Distinct microRNA signature and suppression of ZFP36L1 define ASCL1-positive lung adenocarcinoma
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  91. aacrjournals.org aacrjournals.org
    Integrative multi-omics analysis reveals different metabolic phenotypes based on molecular characteristics in thyroid cancer
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  92. www.biorxiv.org www.biorxiv.org
    Loss of UBE3A impacts both neuronal and non-neuronal cells in human cerebral organoids
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      DOI: 10.1101/2024.02.09.579672

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  93. genomebiology.biomedcentral.com genomebiology.biomedcentral.com
    The androgen receptor interacts with GATA3 to transcriptionally regulate a luminal epithelial cell phenotype in breast cancer
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      DOI: 10.1186/s13059-023-03161-y

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  94. Jan 2024
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ccr2+ monocyte-derived macrophages influence trajectories of acquired therapy resistance in Braf-mutant melanoma
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      DOI: 10.1158/0008-5472.CAN-22-2841

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  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NLRP3 inflammasome activation and symptom burden in KRAS-mutated CMML patients is reverted by IL-1 blocking therapy
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      DOI: 10.1016/j.xcrm.2023.101329

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  97. link.springer.com link.springer.com
    Med23 deficiency reprograms the tumor microenvironment to promote lung tumorigenesis
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      DOI: 10.1038/s41416-023-02556-9

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  98. Dec 2023
  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Topoisomerase 1 Inhibition in MYC-Driven Cancer Promotes Aberrant R-Loop Accumulation to Induce Synthetic Lethality
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  100. link.springer.com link.springer.com
    Dual targeting of MAPK and PI3K pathways unlocks redifferentiation of Braf-mutated thyroid cancer organoids
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      DOI: 10.1038/s41388-023-02889-y

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  101. link.springer.com link.springer.com
    The DNA/RNA helicase DHX9 orchestrates the KDM2B-mediated transcriptional regulation of YAP1 in Ewing sarcoma
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      DOI: 10.1038/s41388-023-02894-1

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  102. 52.53.155.43 52.53.155.43
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  103. Nov 2023
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Concurrent targeting of HDAC and PI3K to overcome phenotypic heterogeneity of castration-resistant and neuroendocrine prostate cancers
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    1. scibot 26 Nov 2023
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  105. www.nature.com www.nature.com
    Selective inhibition of CDK9 in triple negative breast cancer
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      DOI: 10.1038/s41388-023-02892-3

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  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IL23R as an indicator of immune infiltration and poor prognosis in intrahepatic cholangiocarcinoma: a bioinformatics analysis
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  107. dx.doi.org dx.doi.org
    Population-specific Mutation Patterns in Breast Tumors from African American, European American, and Kenyan Patients
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  108. www.biorxiv.org www.biorxiv.org
    A spatially-tracked single cell transcriptomics map of neuronal networks in the intrinsic cardiac nervous system
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      DOI: 10.1101/2020.07.29.227090

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  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Divergence of TORC1-mediated stress response leads to novel acquired stress resistance in a pathogenic yeast
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      DOI: 10.1371/journal.ppat.1011748

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  110. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ATM-inhibitor AZD1390 is a radiosensitizer for breast cancer CNS metastasis
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  111. www.biorxiv.org www.biorxiv.org
    ZNF397 Loss Triggers TET2-driven Epigenetic Rewiring, Lineage Plasticity, and AR-targeted Therapy Resistance in AR-dependent Cancers
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      DOI: 10.1101/2023.10.24.563645

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  112. Oct 2023
  113. www.sciencedirect.com www.sciencedirect.com
    Identifying genetic determinants of Streptococcus pyogenes-host interactions in a murine intact skin infection model
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      DOI: 10.1016/j.celrep.2023.113332

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  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Spatial Profiling of Circular RNAs in Cancer Reveals High Expression in Muscle and Stromal Cells
    2
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      DOI: 10.1158/0008-5472.CAN-23-0748

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  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The effect of chronic lithium treatment on hippocampal progenitor cells: Transcriptomic analysis and systems pharmacology
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  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multi-omic profiling of the developing human cerebral cortex at the single-cell level
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      DOI: 10.1126/sciadv.adg3754

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  117. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting MALAT1 Augments Sensitivity to PARP Inhibition by Impairing Homologous Recombination in Prostate Cancer
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  118. 52.53.155.43 52.53.155.43
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  119. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Prognostic Markers of DNA Methylation and Next-Generation Sequencing in Progressive Glioblastoma from the EORTC-26101 Trial
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  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive Analysis of Tumor Microenvironment Reveals Prognostic ceRNA Network Related to Immune Infiltration in Sarcoma
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      DOI: 10.1158/1078-0432.CCR-22-3396

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  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Methylation Signature Implicated in Immuno-Suppressive Activities in Tubo-Ovarian High-Grade Serous Carcinoma
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      DOI: 10.1158/1055-9965.EPI-22-0941

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  122. www.sciencedirect.com www.sciencedirect.com
    Prenatal alcohol alters inflammatory signatures in enteric portal tissues following adult-onset cerebrovascular ischemic stroke
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      DOI: 10.1016/j.isci.2023.107920

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  123. Sep 2023
  124. www.sciencedirect.com www.sciencedirect.com
    YAP/TEAD-induced PRIM1 contributes to the progression and poor prognosis of gastric carcinoma
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      DOI: 10.1016/j.tranon.2023.101791

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  125. 52.53.155.43 52.53.155.43
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  126. dx.doi.org dx.doi.org
    Targeting KDM2A Enhances T Cell Infiltration in NSD1-Deficient Head and Neck Squamous Cell Carcinoma
    1
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      DOI: 10.1158/0008-5472.CAN-22-3114

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    dx.doi.org/10.1158/0008-5472.CAN-22-3114
  127. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activin A-mediated polarization of cancer-associated fibroblasts and macrophages confers resistance to checkpoint immunotherapy in skin cancer
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    1. scibot 07 Sep 2023
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      DOI: 10.1158/1078-0432.CCR-23-0219

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    ncbi.nlm.nih.gov/pmc/articles/PMC10472111/
  128. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Prognosis signature for predicting the survival and immunotherapy response in esophageal carcinoma based on cellular senescence-related genes
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      DOI: 10.3389/fonc.2023.1203351

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    ncbi.nlm.nih.gov/pmc/articles/PMC10470646/
  129. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metabolic signature and proteasome activity controls synovial migration of CDC42hi CD14+ cells in rheumatoid arthritis
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  130. Aug 2023
  131. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRTAC1 enhances the chemosensitivity of non-small cell lung cancer to cisplatin by eliciting RyR-mediated calcium release and inhibiting Akt1 expression
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      DOI: 10.1038/s41419-023-06088-1

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  132. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrated single cell and bulk sequencing analysis identifies tumor reactive CXCR6+ CD8 T cells as a predictor of immune infiltration and immunotherapy outcomes in hepatocellular carcinoma
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  133. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activator protein-1 (AP-1) signaling inhibits the growth of Ewing sarcoma cells in response to DNA replication stress
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  134. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Network analysis identifies strain-dependent response to tau and tau seeding-associated genes
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  135. www.nature.com www.nature.com
    Tertiary lymphoid structures correlate with enhancement of antitumor immunity in esophageal squamous cell carcinoma
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      DOI: 10.1038/s41416-023-02396-7

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  136. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Kinase Inhibitor Pulldown Assay Identifies a Chemotherapy Response Signature in Triple-negative Breast Cancer Based on Purine-binding Proteins
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  137. www.biorxiv.org www.biorxiv.org
    Overcome Prostate Cancer Resistance to Immune Checkpoint Therapy with Ketogenic Diet-Induced Epigenetic Reprogramming
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      DOI: 10.1101/2023.08.07.552383

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  138. 52.53.155.43 52.53.155.43
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  139. 52.53.155.43 52.53.155.43
    mcr-22-0916-html.html
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  140. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    β-Catenin Drives Butyrophilin-like Molecule Loss and γδ T-cell Exclusion in Colon Cancer
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  141. aacrjournals.org aacrjournals.org
    Clinical importance of the lncRNA NEAT1 in cancer patients treated with immune checkpoint inhibitors.
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    aacrjournals.org/clincancerres/article/29/12/2226/727092/Clinical-Importance-of-the-lncRNA-NEAT1-in-Cancer
  142. dx.doi.org dx.doi.org
    Integrative single-cell and bulk transcriptomes analyses identify intrinsic HNSCC subtypes with distinct prognoses and therapeutic vulnerabilities
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  143. aacrjournals.org aacrjournals.org
    Hypoxia-responsive lncRNA AC115619 encodes a micropeptide that suppresses m6A modifications and hepatocellular carcinoma progression
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      DOI: 10.1158/0008-5472.CAN-23-0337

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    aacrjournals.org/cancerres/article/83/15/2496/728089/Hypoxia-Responsive-lncRNA-AC115619-Encodes-a
  144. 52.53.155.43 52.53.155.43
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      DOI: 10.1158/0008-5472.CAN-22-3860

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  145. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dynamic intestinal stem cell plasticity and lineage remodeling by a nutritional environment relevant to human risk for tumorigenesis
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      DOI: 10.1158/1541-7786.MCR-22-1000

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  146. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BET Inhibitors Target the SCLC-N subtype of Small Cell Lung Cancer by Blocking NEUROD1 Transactivation
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      DOI: 10.1158/1541-7786.MCR-22-0594

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  147. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The kidney protects against sepsis by producing systemic uromodulin
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      DOI: 10.1152/ajprenal.00146.2022

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  148. Jul 2023
  149. link.springer.com link.springer.com
    Establishment of a prognostic model based on m6A regulatory factors and stemness of hepatocellular carcinoma using RNA-seq data and scRNA-seq data
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      DOI: 10.1007/s00432-023-05045-x

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  150. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cancer cell employs a microenvironmental neural signal trans-activating nucleus-mitochondria coordination to acquire stemness
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      DOI: 10.1038/s41392-023-01487-4

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  151. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptional Antagonism by CDK8 Inhibition Improves Therapeutic Efficacy of MEK Inhibitors
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      DOI: 10.1158/0008-5472.CAN-21-4309

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  152. www.science.org www.science.org
    Targeting the chromatin effector Pygo2 promotes cytotoxic T cell responses and overcomes immunotherapy resistance in prostate cancer
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      DOI: 10.1126/sciimmunol.ade4656

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  153. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Immunological modifications following chemotherapy are associated with delayed recurrence of ovarian cancer
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      RRID:SCR_005012

      DOI: 10.3389/fimmu.2023.1204148

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  154. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aged/Autoimmune B-cell Program Defines the Early Transformation of Extranodal Lymphomas
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      DOI: 10.1158/2159-8290.CD-22-0561

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  155. 52.53.155.43 52.53.155.43
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  156. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Caffeine supplementation and FOXM1 inhibition enhance the antitumor effect of statins in neuroblastoma
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      DOI: 10.1158/0008-5472.CAN-22-3450

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  157. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The diagnostic significance of the ZNF gene family in pancreatic cancer: a bioinformatics and experimental study
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      DOI: 10.3389/fgene.2023.1089023

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  158. 52.53.155.43 52.53.155.43
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      RRID:SCR_005012

      DOI: 10.1158/1078-0432.ccr-22-3714

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  159. Jun 2023
  160. www.biorxiv.org www.biorxiv.org
    Divergence of TORC1-mediated Stress Response Leads to Novel Acquired Stress Resistance in a Pathogenic Yeast
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      DOI: 10.1101/2023.06.20.545716

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  161. www.sciencedirect.com www.sciencedirect.com
    Microsatellite instability states serve as predictive biomarkers for tumors chemotherapy sensitivity
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      DOI: 10.1016/j.isci.2023.107045

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  162. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting fatty acid reprogramming suppresses CARM1-expressing ovarian cancer
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      DOI: 10.1158/2767-9764.CRC-23-0030

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  163. www.medrxiv.org www.medrxiv.org
    Metabolic signature and proteasome activity controls synovial migration of CDC42hiCD14+ cells in rheumatoid arthritis
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      DOI: 10.1101/2023.06.15.23291416

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  164. aacrjournals.org aacrjournals.org
    Targeted MDM2 degradation reveals a new vulnerability for p53 inactivated triple negative breast cancer
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    aacrjournals.org/cancerdiscovery/article/13/5/1210/726189/Targeted-MDM2-Degradation-Reveals-a-New
  165. aacrjournals.org aacrjournals.org
    FOXA1 reprogramming dictates retinoid X receptor response in ESR1 mutant breast cancer
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      DOI: 10.1158/1541-7786.MCR-22-0516

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    aacrjournals.org/mcr/article/21/6/591/726508/FOXA1-Reprogramming-Dictates-Retinoid-X-Receptor
  166. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Sortilin acts as an endocytic receptor for α-synuclein fibril
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      DOI: 10.1096/fj.202201605RR

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  167. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    iBRIDGE: A Data Integration Method to Identify Inflamed Tumors from Single-Cell RNAseq Data and Differentiate Cell Type–Specific Markers of Immune-Cell Infiltration
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    1. scibot 07 Jun 2023
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  168. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-Cell RNA Sequencing Unifies Developmental Programs of Esophageal and Gastric Intestinal Metaplasia
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      DOI: 10.1158/2159-8290.CD-22-0824

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  169. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activating an Adaptive Immune Response with a Telomerase-mediated Telomere Targeting Therapeutic in Hepatocellular Carcinoma
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      DOI: 10.1158/1535-7163.MCT-23-0039

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  170. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Tumor-suppressive Molecular Axis EP300/circRERE/miR-6837-3p/MAVS Activates Type I IFN Pathway and Antitumor Immunity to Suppress Colorectal Cancer
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  171. aacrjournals.org aacrjournals.org
    A self-propagating c-Met-SOX2 axis drives cancer-derived IgG signaling that promotes lung cancer cell stemness
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    aacrjournals.org/cancerres/article/83/11/1866/726450/A-Self-Propagating-c-Met-SOX2-Axis-Drives-Cancer
  172. aacrjournals.org aacrjournals.org
    Cancer-associated fibroblast-derived miR-146a-5p generates a niche that promotes bladder cancer stemness and chemoresistance
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    aacrjournals.org/cancerres/article/83/10/1611/726305/Cancer-Associated-Fibroblast-Derived-miR-146a-5p
  173. aacrjournals.org aacrjournals.org
    Enhanced glutaminolysis drives hypoxia-induced chemoresistance in pancreatic cancer
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      DOI: 10.1158/0008-5472.CAN-22-2045

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    aacrjournals.org/cancerres/article/83/5/735/716680/Enhanced-Glutaminolysis-Drives-Hypoxia-Induced
  174. aacrjournals.org aacrjournals.org
    HAND2 assists MYCN enhancer invasion to regulate a noradrenergic neuroblastoma phenotype
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      DOI: 10.1158/0008-5472.CAN-22-2042

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    aacrjournals.org/cancerres/article/83/5/686/716682/HAND2-Assists-MYCN-Enhancer-Invasion-to-Regulate-a
  175. aacrjournals.org aacrjournals.org
    Targeting CHAF1B enhances Interferon activity against Myeloproliferative Neoplasm cells
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  176. 52.53.155.43 52.53.155.43
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  177. 52.53.155.43 52.53.155.43
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  178. 52.53.155.43 52.53.155.43
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  179. May 2023
  180. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Evolution of Resistance to Irinotecan in Cancer Cells Involves Generation of Topoisomerase-Guided Mutations in Non-Coding Genome That Reduce the Chances of DNA Breaks
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    1. scibot 31 May 2023
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      DOI: 10.3390/ijms24108717

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  181. 52.53.155.43 52.53.155.43
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  182. 52.53.155.43 52.53.155.43
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  183. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Analysis of candidate genes for cleft lip ± cleft palate using murine single-cell expression data
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      DOI: 10.3389/fcell.2023.1091666

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  184. www.embopress.org www.embopress.org
    Oxidative stress enhances the therapeutic action of a respiratory inhibitor in MYC-driven lymphoma
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      DOI: 10.15252/emmm.202216910

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  185. www.nature.com www.nature.com
    Reversible transitions between noradrenergic and mesenchymal tumor identities define cell plasticity in neuroblastoma
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      DOI: 10.1038/s41467-023-38239-5

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  186. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Patterns of Oncogene Coexpression at Single-Cell Resolution Influence Survival in Lymphoma
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      DOI: 10.1158/2159-8290.CD-22-0998

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  187. insight.jci.org insight.jci.org
    Tumor propagating side population cells are a dynamic subpopulation in undifferentiated pleomorphic sarcoma
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      DOI: 10.1172/jci.insight.148768

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  188. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    18F-FMISO PET Imaging Identifies Hypoxia and Immunosuppressive Tumor Microenvironments and Guides Targeted Evofosfamide Therapy in Tumors Refractory to PD-1 and CTLA-4 Inhibition
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      DOI: 10.1158/1078-0432.CCR-21-2394

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  189. aacrjournals.org aacrjournals.org
    Transcriptional repression by FoxM1 suppresses tumor differentiation and promotes metastasis of breast cancer
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      DOI: 10.1158/0008-5472.CAN-22-0410

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    aacrjournals.org/cancerres/article/82/13/2458/705024/Transcriptional-Repression-by-FoxM1-Suppresses
  190. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Mesenchymal Tumor Cell State Confers Increased Dependency on the BCL-XL Anti-apoptotic Protein in Kidney Cancer
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      DOI: 10.1158/1078-0432.CCR-22-0669

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  191. Apr 2023
  192. www.biorxiv.org www.biorxiv.org
    Xrp1 governs the stress response program to spliceosome dysfunction
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      DOI: 10.1101/2023.04.06.535851

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    biorxiv.org/content/10.1101/2023.04.06.535851v1
  193. www.nature.com www.nature.com
    Spatial and temporal dynamics of ATP synthase from mitochondria toward the cell surface
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      DOI: 10.1038/s42003-023-04785-3

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  194. www.sciencedirect.com www.sciencedirect.com
    Elevated enhancer-oncogene contacts and higher oncogene expression levels by recurrent CTCF inactivating mutations in acute T cell leukemia
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      DOI: 10.1016/j.celrep.2023.112373

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  195. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia
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      DOI: 10.1158/0008-5472.CAN-22-2129

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  196. Mar 2023
  197. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proteasome Inhibitors Silence Oncogenes in Multiple Myeloma through Localized Histone Deacetylase 3 Stabilization and Chromatin Condensation
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      DOI: 10.1158/2767-9764.CRC-22-0255

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  198. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive analysis of autophagy-related clusters and individual risk model for immunotherapy response prediction in gastric cancer
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  199. www.science.org www.science.org
    Targeting the chromatin effector Pygo2 promotes cytotoxic T cell responses and overcomes immunotherapy resistance in prostate cancer
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      DOI: 10.1126/sciimmunol.ade4656

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  200. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Smoking-associated Downregulation of FILIP1L Enhances Lung Adenocarcinoma Progression Through Mucin Production, Inflammation, and Fibrosis
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      DOI: 10.1158/2767-9764.CRC-22-0233

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  201. www.pnas.org www.pnas.org
    Mouse models of human multiple myeloma subgroups
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      DOI: 10.1073/pnas.2219439120

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  202. Feb 2023
  203. link.springer.com link.springer.com
    The 27-gene IO score is associated with efficacy of PD-1/L1 inhibitors independent of FGFR expression in a real-world metastatic urothelial carcinoma cohort
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      DOI: 10.1007/s00262-023-03401-x

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  204. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RASGRP2 is a potential immune-related biomarker and regulates mitochondrial-dependent apoptosis in lung adenocarcinoma
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      DOI: 10.3389/fimmu.2023.1100231

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  205. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phenotypic screening platform identifies statins as enhancers of immune cell-induced cancer cell death
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      DOI: 10.1186/s12885-023-10645-4

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  206. 52.53.155.43 52.53.155.43
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      DOI: 10.1158/1541-7786.mcr-22-0594

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  207. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Endo180 (MRC2) Antibody–Drug Conjugate for the Treatment of Sarcoma
    1
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      DOI: 10.1158/1535-7163.MCT-22-0312

      Resource: Gene Expression Omnibus (GEO) (RRID:SCR_005012)

      Curator: @scibot

      SciCrunch record: RRID:SCR_005012

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      RRID:SCR_005012
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    ncbi.nlm.nih.gov/pmc/articles/PMC9890142/