4,620 Matching Annotations
  1. Jan 2024
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    Multi-targeted loss of the antigen presentation molecule MR1 during HSV-1 and HSV-2 infection
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    sciencedirect.com/science/article/pii/S2589004224000221
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aldolase B-driven lactagenesis and CEACAM6 activation promote cell renewal and chemoresistance in colorectal cancer through the Warburg effect
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    ncbi.nlm.nih.gov/pmc/articles/PMC10564793/
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    A novel antagonist of the CCL5/CCR5 axis suppresses the tumor growth and metastasis of triple-negative breast cancer by CCR5-YAP1 regulation
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    sciencedirect.com/science/article/pii/S0304383524000296
  5. www.science.org www.science.org
    SUMO-activated target traps (SATTs) enable the identification of a comprehensive E3-specific SUMO proteome
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    science.org/doi/10.1126/sciadv.adh2073
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Vitamin B6 competition in the tumor microenvironment hampers antitumor functions of NK cells.
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    ncbi.nlm.nih.gov/pmc/articles/PMC10784745/
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The intracellular C-terminus confers compartment-specific targeting of voltage-gated Ca2+ channels
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    ncbi.nlm.nih.gov/pmc/articles/PMC10769351/
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    SUMOylated IL-33 in the nucleus stabilizes the transcription factor IRF1 in hepatocellular carcinoma cells to promote immune escape
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    science.org/doi/10.1126/scisignal.abq3362
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    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13587
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    ORF3c is expressed in SARS‐CoV‐2‐infected cells and inhibits innate sensing by targeting MAVS
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    ncbi.nlm.nih.gov/pmc/articles/PMC10702836/
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    Suppression of the KRAS-NRF2 axis shifts arginine into the phosphocreatine energy system in pancreatic cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10746371/
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    Replicative fitness and pathogenicity of primate lentiviruses in lymphoid tissue, primary human and chimpanzee cells: relation to possible jumps to humans
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    sciencedirect.com/science/article/pii/S2352396423005315
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    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17044
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    Direct translation of incoming retroviral genomes
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    ncbi.nlm.nih.gov/pmc/articles/PMC10770327/
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Entrectinib inhibits NLRP3 inflammasome and inflammatory diseases by directly targeting NEK7
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    ncbi.nlm.nih.gov/pmc/articles/PMC10772347/
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    SARS-CoV-2 NSP14 MTase activity is critical for inducing canonical NF-κB activation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10776897/
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Heteromultimeric sarbecovirus receptor binding domain immunogens primarily generate variant-specific neutralizing antibodies
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    ncbi.nlm.nih.gov/pmc/articles/PMC10740387/
  18. www.science.org www.science.org
    RHOAL57V drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling
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    science.org/doi/10.1126/scisignal.adg5289
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    Response to Bruton’s tyrosine kinase inhibitors in aggressive lymphomas linked to chronic selective autophagy
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    sciencedirect.com/science/article/pii/S1535610823004476
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    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13563
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    Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma
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    sciencedirect.com/science/article/pii/S1097276523010225
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    Therapeutic application of human type 2 innate lymphoid cells via induction of granzyme B-mediated tumor cell death
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    sciencedirect.com/science/article/pii/S0092867423013478
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    HMGB1 in exosomes derived from gastric cancer cells induces M2-like macrophage polarization by inhibiting the NF-κB signaling pathway
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    onlinelibrary.wiley.com/doi/10.1002/cbin.12110
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    Structural and functional basis of VLDLR usage by Eastern equine encephalitis virus
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    sciencedirect.com/science/article/pii/S0092867423013181
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    KH-like domains in PARP9/DTX3L and PARP14 coordinate protein-protein interactions to promote cancer cell survival
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    sciencedirect.com/science/article/pii/S002228362300551X
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    Cleavage of the pseudoprotease iRhom2 by the signal peptidase complex reveals an ER-to-nucleus signaling pathway
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    sciencedirect.com/science/article/pii/S1097276523010328
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    PZR suppresses innate immune response to RNA viral infection by inhibiting MAVS activation in interferon signaling mediated by RIG-I and MDA5
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    sciencedirect.com/science/article/pii/S0166354224000056
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    SARS-CoV-2 BA.2.86 enters lung cells and evades neutralizing antibodies with high efficiency
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    sciencedirect.com/science/article/pii/S0092867423013995
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    CHCHD4-TRIAP1 regulation of innate immune signaling mediates skeletal muscle adaptation to exercise
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    sciencedirect.com/science/article/pii/S2211124723016376
  30. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    cAMP-phosphodiesterase 4D7 (PDE4D7) forms a cAMP signalosome complex with DHX9 and is implicated in prostate cancer progression
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13572
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    Metabolic switch regulates lineage plasticity and induces synthetic lethality in triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S1550413123004552
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    The FANCI/FANCD2 complex links DNA damage response to R-loop regulation through SRSF1-mediated mRNA export
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    sciencedirect.com/science/article/pii/S2211124723016224
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    Genetic insights into carbohydrate sulfotransferase 8 and its impact on the immunotherapy efficacy of cancer
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    sciencedirect.com/science/article/pii/S2211124723016522
  34. Dec 2023
  35. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13568
  36. www.biorxiv.org www.biorxiv.org
    New submission 31/07/2023, 09:07:20
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    biorxiv.org/content/10.1101/2023.06.24.546170v2
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    An ERK5-PFKFB3 axis regulates glycolysis and represents a therapeutic vulnerability in pediatric diffuse midline glioma
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    sciencedirect.com/science/article/pii/S2211124723015693
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    Metabolic regulation of homologous recombination repair by MRE11 lactylation
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    sciencedirect.com/science/article/pii/S009286742301276X
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    Decoupling NAD+ metabolic dependency in chondrosarcoma by targeting the SIRT1-HIF-2α axis
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    sciencedirect.com/science/article/pii/S2666379123005591
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    Non-canonical Hedgehog signaling mediates profibrotic hematopoiesis-stroma crosstalk in myeloproliferative neoplasms
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    sciencedirect.com/science/article/pii/S2211124723016200
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    The HLA-II immunopeptidome of SARS-CoV-2
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    sciencedirect.com/science/article/pii/S221112472301608X
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    Serine-129 phosphorylation of α-synuclein is an activity-dependent trigger for physiologic protein-protein interactions and synaptic function
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    sciencedirect.com/science/article/pii/S0896627323008942
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    Subcytoplasmic location of translation controls protein output
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    sciencedirect.com/science/article/pii/S109727652300970X
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    De novo NAD+ synthesis contributes to CD8+ T cell metabolic fitness and antitumor function
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    sciencedirect.com/science/article/pii/S2211124723015309
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    TRPC4 deletion elicits behavioral defects in sociability by dysregulating expression of microRNA-138-2
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    sciencedirect.com/science/article/pii/S2589004223026949
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    Brain-wide circuit-specific targeting of astrocytes
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    sciencedirect.com/science/article/pii/S2667237523003247
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    Tumor-immune microenvironment and NRF2 associate with clinical efficacy of PD-1 blockade combined with chemotherapy in lung squamous cell carcinoma
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    sciencedirect.com/science/article/pii/S2666379123004962
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    Strengthening E-cadherin adhesion via antibody-mediated binding stabilization
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    sciencedirect.com/science/article/pii/S0969212623004045
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    The MHC-E peptide ligands for checkpoint CD94/NKG2A are governed by inflammatory signals, whereas LILRB1/2 receptors are peptide indifferent
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    sciencedirect.com/science/article/pii/S2211124723015280
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    The tetrapeptide sequence of IL-18 and IL-1β regulates their recruitment and activation by inflammatory caspases
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    sciencedirect.com/science/article/pii/S2211124723015930
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    ASCL1 characterizes adrenergic neuroblastoma via its pioneer function and cooperation with core regulatory circuit factors
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    sciencedirect.com/science/article/pii/S221112472301553X
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    FANCD2-dependent mitotic DNA synthesis relies on PCNA K164 ubiquitination
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    sciencedirect.com/science/article/pii/S2211124723015358
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    iPSC-derived hypoimmunogenic tissue resident memory T cells mediate robust anti-tumor activity against cervical cancer
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    sciencedirect.com/science/article/pii/S266637912300544X
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    Proteomic characterization of the colorectal cancer response to chemoradiation and targeted therapies reveals potential therapeutic strategies
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    sciencedirect.com/science/article/pii/S2666379123005050
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    MeCP2 represses the activity of topoisomerase IIβ in long neuronal genes
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    sciencedirect.com/science/article/pii/S2211124723015504
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    Synonymous codon usage regulates translation initiation
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    sciencedirect.com/science/article/pii/S2211124723014250
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    Reprogramming of tumor-associated macrophages via NEDD4-mediated CSF1R degradation by targeting USP18
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    sciencedirect.com/science/article/pii/S2211124723015723
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ubiquiton—An inducible, linkage-specific polyubiquitylation tool
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    ncbi.nlm.nih.gov/pmc/articles/PMC10804999/
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide screen reveals Rab12 GTPase as a critical activator of Parkinson’s disease-linked LRRK2 kinase
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    ncbi.nlm.nih.gov/pmc/articles/PMC10708890/
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutational impact of APOBEC3A and APOBEC3B in a human cell line and comparisons to breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10715669/
  61. www.mdpi.com www.mdpi.com
    Androgen Receptor/AP-1 Activates UGT2B15 Transcription to Promote Esophageal Squamous Cell Carcinoma Invasion
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    mdpi.com/2072-6694/15/24/5719
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    Identification of putative allosteric inhibitors of BCKDK via virtual screening and biological evaluation
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    tandfonline.com/doi/abs/10.1080/14756366.2023.2290458
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Propylene glycol inactivates respiratory viruses and prevents airborne transmission
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    ncbi.nlm.nih.gov/pmc/articles/PMC10701621/
  64. www.science.org www.science.org
    A single-cell multi-omic atlas spanning the adult rhesus macaque brain
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    science.org/doi/10.1126/sciadv.adh1914
  65. link.springer.com link.springer.com
    Modulating signalling lifetime to optimise a prototypical animal opsin for optogenetic applications
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    link.springer.com/article/10.1007/s00424-023-02879-9
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CAR T-cell design-dependent remodeling of the brain tumor-immune microenvironment modulates tumor-associated macrophages and anti-glioma activity
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    ncbi.nlm.nih.gov/pmc/articles/PMC10689147/
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Helicobacter pylori CagA promotes immune evasion of gastric cancer by upregulating PD-L1 level in exosomes
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    ncbi.nlm.nih.gov/pmc/articles/PMC10692710/
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    Deep immunological imprinting due to the ancestral spike in the current bivalent COVID-19 vaccine
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    sciencedirect.com/science/article/pii/S2666379123004354
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    53BP1 interacts with the RNA primer from Okazaki fragments to support their processing during unperturbed DNA replication
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    sciencedirect.com/science/article/pii/S2211124723014249
  70. www.nature.com www.nature.com
    Pyroptosis inhibiting nanobodies block Gasdermin D pore formation
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    nature.com/articles/s41467-023-43707-z
  71. www.thelancet.com www.thelancet.com
    Nicotinamide mononucleotide impacts HIV-1 infection by modulating immune activation in T lymphocytes and humanized mice
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    thelancet.com/journals/ebiom/article/PIIS2352-3964(23)00443-7/abstract
  72. www.biorxiv.org www.biorxiv.org
    MYC–NFATC2 axis maintains cell cycle and mitochondrial function in AML cells
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    biorxiv.org/content/10.1101/2023.11.15.567209v1
  73. www.biorxiv.org www.biorxiv.org
    A novel antagonist of the CCL5/CCR5 axis suppresses the tumor growth and metastasis of triple-negative breast cancer by CCR5-YAP1 regulation
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    biorxiv.org/content/10.1101/2023.11.15.567291v1
  74. 52.53.155.43 52.53.155.43
    Distinctive Interactomes of RNA polymerase II phosphorylation during different stages of transcription
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    52.53.155.43/e1f86bc1b78d4710d3685a727edad6313e1f1c49/1-s2.0-S2589004223016589-main-html.html
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    circWSB1 promotes tumor progression in ccRCC via circWSB1/miR-182-5p/WSB1 axis
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    sciencedirect.com/science/article/pii/S0141813023052376
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    ccr-23-1143-html.html
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    can-23-1038-html.html
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  78. Nov 2023
  79. www.sciencedirect.com www.sciencedirect.com
    Super-enhancer trapping by the nuclear pore via intrinsically disordered regions of proteins in squamous cell carcinoma cells
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    sciencedirect.com/science/article/pii/S2451945623003665
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    The RNA helicase DDX39A binds a conserved structure in chikungunya virus RNA to control infection
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    sciencedirect.com/science/article/pii/S1097276523008420
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    K6-linked ubiquitylation marks formaldehyde-induced RNA-protein crosslinks for resolution
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    sciencedirect.com/science/article/pii/S1097276523008481
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    Abundant binary promoter switches in lineage-determining transcription factors indicate a digital component of cell fate determination
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    sciencedirect.com/science/article/pii/S2211124723014663
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    Targeted perturbation of signaling-driven condensates
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    sciencedirect.com/science/article/pii/S1097276523008602
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    Copine-6 is a Ca2+ sensor for activity-induced AMPA receptor exocytosis
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    sciencedirect.com/science/article/pii/S2211124723014729
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    SERPINB3-MYC axis induces the basal-like/squamous subtype and enhances disease progression in pancreatic cancer
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    sciencedirect.com/science/article/pii/S2211124723014468
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    Nuclear RNA catabolism controls endogenous retroviruses, gene expression asymmetry, and dedifferentiation
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    sciencedirect.com/science/article/pii/S1097276523009036
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    SARS-CoV-2 ORF6 protein targets TRIM25 for proteasomal degradation to diminish K63-linked RIG-I ubiquitination and type-I interferon induction
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    link.springer.com/article/10.1007/s00018-023-05011-3
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    Multiple, short protein binding motifs in ORC1 and CDC6 control the initiation of DNA replication
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    sciencedirect.com/science/article/pii/S1097276521001714
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Five Inhibitory Receptors Display Distinct Vesicular Distributions in Murine T Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10649679/
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    A genome-wide CRISPR screen identifies USP1 as a novel regulator of the mammalian circadian clock
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