4,620 Matching Annotations
  1. May 2023
  2. www.biorxiv.org www.biorxiv.org
    Zfp106 binds to G-quadruplex RNAs and inhibits RAN translation and formation of RNA foci caused by G4C2 repeats
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    biorxiv.org/content/10.1101/2023.03.05.531055v1
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    Modelling the association between neutralizing antibody levels and SARS-CoV-2 viral dynamics : implications to define correlates of protection against infection
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    medrxiv.org/content/10.1101/2023.03.05.23286816v1
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    L1 retrotransposons drive human neuronal transcriptome complexity and functional diversification
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    biorxiv.org/content/10.1101/2023.03.04.531072v1
  5. Apr 2023
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nonlytic Quasi-Enveloped Hepatovirus Release Is Facilitated by pX Protein Interaction with the E3 Ubiquitin Ligase ITCH
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    ncbi.nlm.nih.gov/pmc/articles/PMC9645215/
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    A living biobank of patient-derived ductal carcinoma in situ mouse-intraductal xenografts identifies risk factors for invasive progression
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    sciencedirect.com/science/article/pii/S1535610823001289
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    SYVN1 ubiquitinates FoxO1 to induce β-catenin nuclear translocation, PD-L1-mediated metastasis, and immune evasion of hepatocellular carcinoma
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    link.springer.com/article/10.1007/s13402-023-00811-y
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    Genetically encoded sensors for measuring histamine release both in vitro and in vivo
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    sciencedirect.com/science/article/pii/S0896627323001289
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    Cell culture systems for isolation of SARS-CoV-2 clinical isolates and generation of recombinant virus
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    ncbi.nlm.nih.gov/pmc/articles/PMC10083141/
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    Context-dependent requirement of G protein coupling for Latrophilin-2 in target selection of hippocampal axons
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    ncbi.nlm.nih.gov/pmc/articles/PMC10118387/
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    ZFP36-mediated mRNA decay regulates metabolism
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    sciencedirect.com/science/article/pii/S2211124723004229
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    LncRNA modulates Hippo-YAP signaling to reprogram iron metabolism
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    nature.com/articles/s41467-023-37871-5
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    IL-33/ST2 antagonizes STING signal transduction via autophagy in response to acetaminophen-mediated toxicological immunity
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    link.springer.com/article/10.1186/s12964-023-01114-3
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    Cancer Cell Resistance to IFNγ Can Occur via Enhanced Double-Strand Break Repair Pathway Activity
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    aacrjournals.org/cancerimmunolres/article/11/3/381/716712/Cancer-Cell-Resistance-to-IFN-Can-Occur-via
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    Proteomic discovery of chemical probes that perturb protein complexes in human cells
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    sciencedirect.com/science/article/pii/S1097276523002393
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    Electrochemical Bioplatform for the Determination of the Most Common and Carcinogenic Human Papillomavirus DNA
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    sciencedirect.com/science/article/pii/S0731708523001802
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    Induction of PARP7 Creates a Vulnerability for Growth Inhibition by RBN2397 in Prostate Cancer Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10108886/
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    Differential roles of CTP synthetases CTPS1 and CTPS2 in cell proliferation
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    biorxiv.org/content/10.1101/2023.03.29.534741v1
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    Targeting the mevalonate pathway suppresses ARID1A-inactivated cancers by promoting pyroptosis
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    sciencedirect.com/science/article/pii/S1535610823000508
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    Targeting of epigenetic co-dependencies enhances anti-AML efficacy of Menin inhibitor in AML with MLL1-r or mutant NPM1
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    nature.com/articles/s41408-023-00826-6
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    RAF1 deficiency causes a lethal syndrome that underscores RTK signaling during embryogenesis
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    embopress.org/doi/10.15252/emmm.202217078
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    Chemical-proteomics Identify Peroxiredoxin-1 as an Actionable Target in Triple-negative Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10092761/
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    Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair
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    Immunogenicity and protective efficacy of GBP510/AS03 vaccine against SARS-CoV-2 delta challenge in rhesus macaques
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    ncbi.nlm.nih.gov/pmc/articles/PMC9947939/
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    Stem cell competition driven by the Axin2-p53 axis controls brain size during murine development
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    sciencedirect.com/science/article/pii/S1534580723001326
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    IKZF4 acts as a novel tumor suppressor in non–small cell lung cancer by suppressing Notch signaling pathway
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    sciencedirect.com/science/article/pii/S0898656823000931
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    Massively parallel characterization of transcriptional regulatory elements in three diverse human cell types
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    ncbi.nlm.nih.gov/pmc/articles/PMC10028905/
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    Distinct regulation of EZH2 and its repressive H3K27me3 mark in Polyomavirus -positive and -negative Merkel cell carcinoma
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    sciencedirect.com/science/article/pii/S0022202X23019735
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    Intronic Cis-Element DR8 in hTERT Is Bound by Splicing Factor SF3B4 and Regulates hTERT Splicing in Non-Small Cell Lung Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9532359/
  32. 52.53.155.43 52.53.155.43
    Human APOBEC3B promotes tumor heterogeneity in vivo including signature mutations and metastases
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    miR‐548ag functions as an oncogene by suppressing MOB1B in the development of obesity‐related endometrial cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10067393/
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR-suppressor scanning for systematic discovery of drug resistance mutations
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    ncbi.nlm.nih.gov/pmc/articles/PMC10073897/
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Spatiotemporal Map of Co-Receptor Signaling Networks Underlying B Cell Activation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10055206/
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Serum neutralizing capacity and T-cell response against the omicron BA.1 variant in seropositive children and their parents one year after SARS-CoV-2 infection
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    ncbi.nlm.nih.gov/pmc/articles/PMC10083310/
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    N-acetylcysteine overcomes NF1 loss-driven resistance to PI3Kα inhibition in breast cancer
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    sciencedirect.com/science/article/pii/S266637912300112X
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    Phosphorylation barcodes direct biased chemokine signaling at CXCR3
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    reader.elsevier.com/reader/sd/pii/S2451945623000855
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ad26.COV2.S and SARS-CoV-2 Spike Protein Ferritin Nanoparticle Vaccine Protect Against SARS-CoV-2 Omicron BA.5 Challenge in Macaques
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    ncbi.nlm.nih.gov/pmc/articles/PMC10040355/
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    γ-Protocadherins control synapse formation and peripheral branching of touch sensory neurons
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    sciencedirect.com/science/article/pii/S0896627323002088
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    The CEP170B-KIF2A complex destabilizes microtubule minus ends to generate polarized microtubule network
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    embopress.org/doi/full/10.15252/embj.2022112953
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    Targeted m6A demethylation of ITGA6 mRNA by a multisite dCasRx–m6A editor inhibits bladder cancer development
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    sciencedirect.com/science/article/pii/S2090123223000929
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    Ultra-rare complement factor 8 coding variants in families with age-related macular degeneration
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    The ancestral ESCRT protein TOM1L2 selects ubiquitinated cargoes for retrieval from cilia
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    sciencedirect.com/science/article/pii/S1534580723000990
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    Escape from oncogene-induced senescence is controlled by POU2F2 and memorized by chromatin scars
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    sciencedirect.com/science/article/pii/S2666979X23000599
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A general method for quantitative fractionation of mammalian cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10040634/
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterization of heterogeneous metabolism in hepatocellular carcinoma identifies new therapeutic target and treatment strategy
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    ncbi.nlm.nih.gov/pmc/articles/PMC10060979/
  48. Mar 2023
  49. www.biorxiv.org www.biorxiv.org
    Structure-guided inhibition of the cancer DNA-mutating enzyme APOBEC3A
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    biorxiv.org/content/10.1101/2023.02.17.528918v1
  50. www.mdpi.com www.mdpi.com
    Screening of Efficient Adjuvants for the RBD-Based Subunit Vaccine of SARS-CoV-2
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    mdpi.com/2076-393X/11/4/713
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    Neofunctionalisation of ciliary BBS proteins to nuclear roles is likely a frequent innovation across eukaryotes
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    sciencedirect.com/science/article/pii/S258900422300487X
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    Phosphoantigen sensing combines TCR-dependent recognition of the BTN3A IgV domain and germline interaction with BTN2A1
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    sciencedirect.com/science/article/pii/S2211124723003327
  53. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Switching ubiquitous and muscle-specific isoforms of mitochondrial respiratory complex IV in skeletal muscle fine-tunes complex IV activity
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202201223RR
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    A micropattern-based assay to study contact inhibition of locomotion and entosis of adherent human and canine cells in vitro
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    sciencedirect.com/science/article/pii/S2666166723001442
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    Temsavir blocks the immunomodulatory activities of HIV-1 soluble gp120
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    Leaked genomic and mitochondrial DNA contribute to the host response to noroviruses in a STING-dependent manner
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    An optimized protocol to detect protein ubiquitination and activation by ubiquitination assay in vivo and CCK-8 assay
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    sciencedirect.com/science/article/pii/S2666166723001570
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NLRC5 affects diet-induced adiposity in female mice and co-regulates peroxisome proliferator-activated receptor PPARγ target genes
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    ncbi.nlm.nih.gov/pmc/articles/PMC10034470/
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    The acetylase activity of Cdu1 protects Chlamydia effectors from degradation to regulate bacterial exit from infected cells
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    biorxiv.org/content/10.1101/2023.02.28.530337v2
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    Induction of viral mimicry upon loss of DHX9 and ADAR1 in breast cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10002699/
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    TRIM28 represses renal cell carcinoma cell proliferation by inhibiting TFE3/KDM6A-regulated autophagy
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    Inter-axonal molecular crosstalk via Lumican proteoglycan sculpts murine cervical corticospinal innervation by distinct subpopulations
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    Differential Optineurin expression controls TGFβ signaling and is a key determinant for metastasis of triple negative breast cancer
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    onlinelibrary.wiley.com/doi/10.1002/ijc.34483
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutating novel interaction sites in NRP1 reduces SARS-CoV-2 spike protein internalization
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    ncbi.nlm.nih.gov/pmc/articles/PMC9957656/
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    A central chaperone-like role for 14-3-3 proteins in human cells
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    A combinatorial approach to uncover an additional Integrator subunit
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    ER proteostasis regulators cell-non-autonomously control sleep
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    Leveraging Tumor Microenvironment Infiltration in Pancreatic Cancer to Identify Gene Signatures Related to Prognosis and Immunotherapy Response
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    ncbi.nlm.nih.gov/pmc/articles/PMC10000708/
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    Novel repertoire of tau biosensors to monitor pathological tau transformation and seeding activity in living cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10014071/
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    CEBPB upregulates P4HA2 to promote the malignant biological behavior in IDH1 wildtype glioma
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    Transient receptor potential canonical type 6 (TRPC6) O-GlcNAcylation at Threonine-221 plays potent role in channel regulation
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    In vivo interrogation of regulatory genomes reveals extensive quasi-insufficiency in cancer evolution
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    Oxygen toxicity causes cyclic damage by destabilizing specific Fe-S cluster-containing protein complexes
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    Linoleic acid potentiates CD8+ T cell metabolic fitness and antitumor immunity
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    Dual IKZF2 and CK1α degrader targets acute myeloid leukemia cells
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    Targeting androgen receptor and the variants by an orally bioavailable Proteolysis Targeting Chimeras compound in castration resistant prostate cancer
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    Lysosomal trafficking of the glucose transporter GLUT1 requires sequential regulation by TXNIP and ubiquitin
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    ncbi.nlm.nih.gov/pmc/articles/PMC9986520/
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    Increased retinoic acid signaling decreases lung metastasis in salivary adenoid cystic carcinoma by inhibiting the noncanonical Notch1 pathway
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    Phosphomimetics at Ser199/Ser202/Thr205 in Tau Impairs Axonal Transport in Rat Hippocampal Neurons
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    S-adenosylhomocysteine hydrolase-like protein 1 (AHCYL1) inhibits lung cancer tumorigenesis by regulating cell plasticity
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    Combined Inhibition of Smoothened and the DNA Damage Checkpoint WEE1 Exerts Antitumor Activity in Cholangiocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9978885/
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A third SARS-CoV-2 mRNA vaccine dose in people receiving hemodialysis overcomes B cell defects but elicits a skewed CD4+ T cell profile
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    A Drug Repurposing Approach Reveals Targetable Epigenetic Pathways in Plasmodium vivax Hypnozoites
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    biorxiv.org/content/10.1101/2023.01.31.526483v3
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    High-throughput screening of functional neo-antigens and their specific TCRs via the Jurkat reporter system combined with droplet microfluidics
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