5,186 Matching Annotations
  1. Mar 2024
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    IL-37 dampens immunosuppressive functions of MDSCs via metabolic reprogramming in the tumor microenvironment
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    sciencedirect.com/science/article/pii/S2211124724001633
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    EPC1/2 regulate hematopoietic stem and progenitor cell proliferation by modulating H3 acetylation and DLST
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    sciencedirect.com/science/article/pii/S258900422400484X
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    SMARCA4 is a haploinsufficient B cell lymphoma tumor suppressor that fine-tunes centrocyte cell fate decisions
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    sciencedirect.com/science/article/pii/S1535610824000552
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    ARID1A orchestrates SWI/SNF-mediated sequential binding of transcription factors with ARID1A loss driving pre-memory B cell fate and lymphomagenesis
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    sciencedirect.com/science/article/pii/S1535610824000540
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    CDK-independent role of D-type cyclins in regulating DNA mismatch repair
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    sciencedirect.com/science/article/pii/S1097276524001291
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13616
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    Transcriptome Regulation by PARP13 in Basal and Antiviral States in Human Cells
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    MTOR modulation induces selective perturbations in histone methylation which influence the anti-proliferative effects of mTOR inhibitors
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    NR4a1/2 deletion promotes accumulation of TCF1+ stem-like precursors of exhausted CD8+ T cells in the tumor microenvironment
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    FH variant pathogenicity promotes purine salvage pathway dependence in kidney cancer
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    Securin acetylation prevents precocious separase activation and premature sister chromatid separation
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    VISTA promotes the metabolism and differentiation of myeloid-derived suppressor cells by STAT3 and polyamine-dependent mechanisms
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    ncbi.nlm.nih.gov/pmc/articles/PMC10851928/
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    Identification and characterization of a potent and selective HUNK inhibitor for treatment of HER2+ breast cancer
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    sciencedirect.com/science/article/pii/S2451945624000370
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    MOF-mediated acetylation of UHRF1 enhances UHRF1 E3 ligase activity to facilitate DNA methylation maintenance
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    In vivo CRISPR screening directly targeting testicular cells
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    A sterol analog inhibits hedgehog pathway by blocking cholesterylation of smoothened
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    Non-canonical isoforms of the mRNA polyadenylation factor WDR33 regulate STING-mediated immune responses
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    Identification of a ΔNp63-Dependent Basal-Like A Subtype-Specific Transcribed Enhancer Program (B-STEP) in Aggressive Pancreatic Ductal Adenocarcinoma
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    A Highlights from MBoC Selection: Neuronal membrane proteasome-derived peptides modulate NMDAR-dependent neuronal signaling to promote changes in gene expression
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    Catalytic activity and autoprocessing of murine caspase-11 mediate noncanonical inflammasome assembly in response to cytosolic LPS
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    elifesciences.org/articles/83725
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    The CARD8 inflammasome dictates HIV/SIV pathogenesis and disease progression
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    The immediate-early protein 1 of human herpesvirus 6B interacts with NBS1 and inhibits ATM signaling
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    Retinoic acid receptor activation reprograms senescence response and enhances anti-tumor activity of natural killer cells
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    PDGFRα+ITGA11+ fibroblasts foster early-stage cancer lymphovascular invasion and lymphatic metastasis via ITGA11-SELE interplay
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    SNUPN deficiency causes a recessive muscular dystrophy due to RNA mis-splicing and ECM dysregulation
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  28. Feb 2024
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    Pathologic α-Synuclein-NOD2 Interaction and RIPK2 Activation Drives Microglia-Induced Neuroinflammation in Parkinson’s Disease
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    Mechanical activation of TWIK-related potassium channel by nanoscopic movement and rapid second messenger signaling
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    PRMT1 acts as a suppressor of MHC-I and anti-tumor immunity
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    Lactate modulates RNA splicing to promote CTLA-4 expression in tumor-infiltrating regulatory T cells
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    The proteomic landscape of genotoxic stress-induced micronuclei
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    Poly(ADP-ribosyl)ation of TIMELESS limits DNA replication stress and promotes stalled fork protection
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    Mycobacterial Rv1804c binds to the PEST domain of IκBα and activates macrophage-mediated proinflammatory responses
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    CYP7B1-mediated 25-hydroxycholesterol degradation maintains quiescence-activation balance and improves therapeutic potential of mesenchymal stem cells
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    Sperm induction of somatic cell-cell fusion as a novel functional test
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    Depletion of PHLDB2 Suppresses Epithelial–Mesenchymal Transition and Enhances Anti-Tumor Immunity in Head and Neck Squamous Cell Carcinoma
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    A tangible method to assess native ferroptosis suppressor activity
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    Single-cell transcriptomics reveals the heterogeneity of the immune landscape of IDH-wildtype high-grade gliomas
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    Alternative Wnt-signaling axis leads to a break of oncogene-induced senescence
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    BHLHE41 Suppresses Osteoclastogenesis and Abnormal Bone Resorption Disease via NFATc1
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    Nuclear GRP78 Promotes Metabolic Reprogramming and Therapeutic Resistance in Pancreatic Ductal Adenocarcinoma
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    Phospholipase PLCE1 promotes transcription and phosphorylation of MCM7 to drive tumor progression in esophageal cancer
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    Therapy-Induced Senescence Contributes to the Efficacy of Abemaciclib in Patients with Dedifferentiated Liposarcoma
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    Adhesion-clutch between DCC and netrin-1 mediates netrin-1–induced axonal haptotaxis
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    PKCμ promotes keratinocyte cell migration through Cx43 phosphorylation-mediated suppression of intercellular communication
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    Denaturing purifications demonstrate that PRC2 and other widely reported chromatin proteins do not appear to bind directly to RNA in vivo
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    53BP1 interacts with the RNA primer from Okazaki fragments to support their processing during unperturbed DNA replication
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    Transactivation of Met signaling by oncogenic Gnaq drives the evolution of melanoma in Hgf-Cdk4 mice
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    IL-37d enhances COP1-mediated C/EBPβ degradation to suppress spontaneous neutrophil migration and tumor progression
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    Suppression of the METTL3-m6A-integrin β1 axis by extracellular acidification impairs T cell infiltration and antitumor activity
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    Shigella induces stress granule formation by ADP-riboxanation of the eIF3 complex
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    Pim kinase inhibitors increase gilteritinib cytotoxicity in FLT3-ITD acute myeloid leukemia through GSK-3β activation and c-Myc and Mcl-1 proteasomal degradation
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    Deposition of onco-histone H3.3-G34W leads to DNA repair deficiency and activates cGAS/STING-mediated immune responses
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    Bioluminescence Imaging Reveals Enhanced SARS-CoV-2 Clearance in Mice with Combinatorial Regimens
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    Epigenetic and transcriptomic characterization reveals progression markers and essential pathways in clear cell renal cell carcinoma
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    Inhibition of O-GlcNAc transferase activates type I interferon-dependent antitumor immunity by bridging cGAS-STING pathway
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    SLC25A51 decouples the mitochondrial NAD+/NADH ratio to control proliferation of AML cells
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    Trichinella spiralis inhibits myoblast differentiation by targeting SQSTM1/p62 with a secreted E3 ubiquitin ligase
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    Tumor-derived Small Extracellular Vesicles Inhibit the Efficacy of CAR T Cells against Solid Tumors
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    Identification and Structural Characterization of a mutant KRAS-G12V specific TCR restricted by HLA-A3
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    Mutation at the Site of Hydroxylation in the Ribosomal Protein uL15 (RPL27a) Causes Specific Changes in the Repertoire of mRNAs Translated in Mammalian Cells
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    A newly identified 45‐kDa JAK2 variant with an altered kinase domain structure represents a novel mode of JAK2 kinase inhibitor resistance
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    Peptidyl-tRNA hydrolysis rate influences the efficiency of nonsense-mediated mRNA decay
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    Redistribution of the glycocalyx exposes phagocytic determinants on apoptotic cells
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    Mosaic sarbecovirus vaccination elicits cross-reactive responses in pre-immunized animals
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    C19ORF84 connects piRNA and DNA methylation machineries to defend the mammalian germ line
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    Isoform-specific RNA structure determination using Nano-DMS-MaP
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    Somatic gene delivery for flexible in vivo modeling of high-risk sarcoma
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    An enhanced broad-spectrum peptide inhibits Omicron variants in vivo
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  82. cancerci.biomedcentral.com cancerci.biomedcentral.com
    NY-ESO-1-specific T cell receptor-engineered T cells and Tranilast, a TRPV2 antagonist bivalent treatment enhances the killing of esophageal cancer: a dual-targeted cancer therapeutic route
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    Dietary elaidic acid boosts tumoral antigen presentation and cancer immunity via ACSL5
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    Peptide-scFv antigen recognition domains effectively confer CAR T cell multiantigen specificity
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    Effector functions are required for broad and potent protection of neonatal mice with antibodies targeting HSV glycoprotein D
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    Three-step docking by WIPI2, ATG16L1, and ATG3 delivers LC3 to the phagophore
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    CRISPR screen for protein inclusion formation uncovers a role for SRRD in the regulation of intermediate filament dynamics and aggresome assembly
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    cAMP-phosphodiesterase 4D7 (PDE4D7) forms a cAMP signalosome complex with DHX9 and is implicated in prostate cancer progression
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13572
  177. www.sciencedirect.com www.sciencedirect.com
    Metabolic switch regulates lineage plasticity and induces synthetic lethality in triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S1550413123004552
  178. www.sciencedirect.com www.sciencedirect.com
    The FANCI/FANCD2 complex links DNA damage response to R-loop regulation through SRSF1-mediated mRNA export
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    sciencedirect.com/science/article/pii/S2211124723016224
  179. www.sciencedirect.com www.sciencedirect.com
    Genetic insights into carbohydrate sulfotransferase 8 and its impact on the immunotherapy efficacy of cancer
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    sciencedirect.com/science/article/pii/S2211124723016522
  180. Dec 2023
  181. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13568
  182. www.biorxiv.org www.biorxiv.org
    New submission 31/07/2023, 09:07:20
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    biorxiv.org/content/10.1101/2023.06.24.546170v2