5,894 Matching Annotations
  1. Nov 2022
  2. www.sciencedirect.com www.sciencedirect.com
    An ancestral mycobacterial effector promotes dissemination of infection
    1
    1. scibot 10 Nov 2022
      RRID:IMSR_JAX:000

      DOI: 10.1016/j.cell.2022.10.019

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    sciencedirect.com/science/article/pii/S0092867422013617
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lipopolysaccharide induces placental mitochondrial dysfunction in murine and human systems by reducing MNRR1 levels via a TLR4-independent pathway
    1
    1. scibot 09 Nov 2022
      Jackson LaboratoryStock# 000664

      DOI: 10.1016/j.isci.2022.105342

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    ncbi.nlm.nih.gov/pmc/articles/PMC9633742/
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phosphorylation of RXRα mediates the effect of JNK to suppress hepatic FGF21 expression and promote metabolic syndrome
    1
    1. scibot 09 Nov 2022
      RRID:IMSR_JAX:000664

      DOI: 10.1073/pnas.2210434119

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    ncbi.nlm.nih.gov/pmc/articles/PMC9636906/
  5. www.sciencedirect.com www.sciencedirect.com
    Mesoscale connections and gene expression empower whole-brain modeling of α-synuclein spread, aggregation, and decay dynamics
    1
    1. scibot 09 Nov 2022
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      DOI: 10.1016/j.celrep.2022.111631

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    sciencedirect.com/science/article/pii/S2211124722015029
  6. link.springer.com link.springer.com
    Dual anti-angiogenic and anti-metastatic activity of myriocin synergistically enhances the anti-tumor activity of cisplatin
    1
    1. scibot 05 Nov 2022
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      DOI: 10.1007/s13402-022-00737-x

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    link.springer.com/article/10.1007/s13402-022-00737-x
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    Engineered human cytokine/antibody fusion proteins expand regulatory T cells and confer autoimmune disease protection
    1
    1. scibot 05 Nov 2022
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      DOI: 10.1016/j.celrep.2022.111478

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    sciencedirect.com/science/article/pii/S2211124722013286
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    Tumor-intrinsic SIRPA promotes sensitivity to checkpoint inhibition immunotherapy in melanoma
    1
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    sciencedirect.com/science/article/pii/S1535610822005037
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    A binocular perception deficit characterizes prey pursuit in developing mice
    1
    1. scibot 04 Nov 2022
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      DOI: 10.1016/j.isci.2022.105368

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    ncbi.nlm.nih.gov/pmc/articles/PMC9626674/
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    Deep tissue infection by an invasive human fungal pathogen requires lipid-based suppression of the IL-17 response
    1
    1. scibot 03 Nov 2022
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    sciencedirect.com/science/article/pii/S1931312822005170
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    Gut colonization by Proteobacteria alters host metabolism and modulates cocaine neurobehavioral responses
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    1. scibot 03 Nov 2022
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    sciencedirect.com/science/article/pii/S193131282200470X
  12. www.jneurosci.org www.jneurosci.org
    Prolactin Action Is Necessary for Parental Behavior in Male Mice
    1
    1. scibot 03 Nov 2022
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      DOI: 10.1523/JNEUROSCI.0558-22.2022

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    jneurosci.org/content/42/44/8308
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    CD74 as a regulator of transcription in normal B cells
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    1. scibot 03 Nov 2022
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      DOI: 10.1016/j.celrep.2022.111572

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    sciencedirect.com/science/article/pii/S2211124722014334
  14. www.sciencedirect.com www.sciencedirect.com
    Melanocortin-4 receptors activate sympathetic preganglionic neurons and elevate blood pressure via TRPV1
    1
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      DOI: 10.1016/j.celrep.2022.111579

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    sciencedirect.com/science/article/pii/S2211124722014401
  15. www.sciencedirect.com www.sciencedirect.com
    Mobilizing phospholipids on tumor plasma membrane implicates phosphatidylserine externalization blockade for cancer immunotherapy
    1
    1. scibot 03 Nov 2022
      RRID:IMSR_JAX:000664

      DOI: 10.1016/j.celrep.2022.111582

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    sciencedirect.com/science/article/pii/S2211124722014474
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    Long-term progression of retinal degeneration in a preclinical model of CLN7 Batten disease as a baseline for testing clinical therapeutics
    1
    1. scibot 03 Nov 2022
      RRID:MSR_JAX:000664

      DOI: 10.1016/j.ebiom.2022.104314

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    sciencedirect.com/science/article/pii/S2352396422004960
  17. elifesciences.org elifesciences.org
    Integration of mouse ovary morphogenesis with developmental dynamics of the oviduct, ovarian ligaments, and rete ovarii
    1
    1. scibot 02 Nov 2022
      Jackson LaboratoryStock #:000664

      DOI: 10.7554/eLife.81088

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    elifesciences.org/articles/81088
  18. Oct 2022
  19. elifesciences.org elifesciences.org
    BehaviorDEPOT is a simple, flexible tool for automated behavioral detection based on markerless pose tracking
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    1. scibot 29 Oct 2022
      JAX Stock No. 000664

      DOI: 10.7554/eLife.74314

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    elifesciences.org/articles/74314
  20. 52.53.155.43 52.53.155.43
    mcr-22-0040-html.html
    1
    1. scibot 28 Oct 2022
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      DOI: 10.1158/1541-7786.MCR-22-0040

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    52.53.155.43/727478f306d650986e0e949733013801988f63e4/mcr-22-0040-html.html
  21. www.nature.com www.nature.com
    CRISPRi screens in human iPSC-derived astrocytes elucidate regulators of distinct inflammatory reactive states
    1
    1. scibot 28 Oct 2022
      RRID:IMSR_JAX:000664

      DOI: 10.1038/s41593-022-01180-9

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    nature.com/articles/s41593-022-01180-9
  22. www.sciencedirect.com www.sciencedirect.com
    High-throughput sequencing of single neuron projections reveals spatial organization in the olfactory cortex
    1
    1. scibot 28 Oct 2022
      RRID:IMSR_JAX:000

      DOI: 10.1016/j.cell.2022.09.038

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    sciencedirect.com/science/article/pii/S0092867422012570
  23. onlinelibrary.wiley.com onlinelibrary.wiley.com
    K+ channel Kv4.1 is expressed in the nociceptors/secondary nociceptive neurons and participates in pain regulation
    1
    1. scibot 27 Oct 2022
      RRID:IMSR_JAX:000664

      DOI: 10.1002/ejp.2038

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    onlinelibrary.wiley.com/doi/10.1002/ejp.2038
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GPCR-Mediated Regulation of Fuel and Energy Metabolism in Peripheral Tissues: Glucagon receptor signaling at white adipose tissue does not regulate lipolysis
    1
    1. scibot 27 Oct 2022
      RRID:IMSR_JAX:000664

      DOI: 10.1152/ajpendo.00078.2022

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    ncbi.nlm.nih.gov/pmc/articles/PMC9576180/
  25. aacrjournals.org aacrjournals.org
    Notch signaling promotes mature T-cell lymphomagenesis
    1
    1. scibot 27 Oct 2022
      RRID:IMSR_JAX:000664

      DOI: 10.1158/0008-5472.CAN-22-1215

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    aacrjournals.org/cancerres/article/82/20/3763/709632/Notch-Signaling-Promotes-Mature-T-Cell
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phosphoproteomic mapping reveals distinct signaling actions and activation of muscle protein synthesis by Isthmin-1
    1
    1. scibot 27 Oct 2022
      RRID:IMSR_JAX:000664

      DOI: 10.7554/eLife.80014

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    ncbi.nlm.nih.gov/pmc/articles/PMC9592085/
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Increased KIF11/Kinesin-5 expression offsets Alzheimer Aβ-mediated toxicity and cognitive dysfunction
    1
    1. scibot 27 Oct 2022
      RRID:IMSR_JAX:000664

      DOI: 10.1016/j.isci.2022.105288

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    ncbi.nlm.nih.gov/pmc/articles/PMC9593841/
  28. www.cell.com www.cell.com
    Systemic vaccination induces CD8+ T cells and remodels the tumor microenvironment
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    1. scibot 27 Oct 2022
      RRID:IMSR_JAX:00066

      DOI: 10.1016/j.cell.2022.10.006

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    cell.com/cell/fulltext/S0092-8674(22)01321-6
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dopaminergic neurons are not a major SHH ligand source for striatal cholinergic or PV interneurons
    2
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      RRID:ISMR_JAX

      DOI: 10.1016/j.isci.2022.105278

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    2. scibot 25 Oct 2022
      JAX:000664

      DOI: 10.1016/j.isci.2022.105278

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    ncbi.nlm.nih.gov/pmc/articles/PMC9587326/
  30. www.sciencedirect.com www.sciencedirect.com
    Gasdermin D restricts anti-tumor immunity during PD-L1 checkpoint blockade
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    1. scibot 26 Oct 2022
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    sciencedirect.com/science/article/pii/S2211124722014097
  31. www.sciencedirect.com www.sciencedirect.com
    A protocol to visualize on-target specific drug binding in mammalian tissue with cellular resolution using tissue clearing and click chemistry
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    sciencedirect.com/science/article/pii/S266616672200658X
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-scale CRISPR screening reveals that C3aR signaling is critical for rapid capture of fungi by macrophages
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      DOI: 10.1371/journal.ppat.1010237

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    ncbi.nlm.nih.gov/pmc/articles/PMC9578593/
  33. www.sciencedirect.com www.sciencedirect.com
    Genome-wide CRISPR screen reveals v-ATPase as a drug target to lower levels of ALS protein ataxin-2
    1
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    sciencedirect.com/science/article/pii/S2211124722013584
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The transcription factor Bach2 negatively regulates murine natural killer cell maturation and function
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      DOI: 10.7554/eLife.77294

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    ncbi.nlm.nih.gov/pmc/articles/PMC9560152/
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Overexpression and ELISA-based detection of asprosin in cultured cells and mice
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      DOI: 10.1016/j.xpro.2022.101762

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  36. www.sciencedirect.com www.sciencedirect.com
    A multienzyme S-nitrosylation cascade regulates cholesterol homeostasis
    1
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      DOI: 10.1016/j.celrep.2022.111538

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    sciencedirect.com/science/article/pii/S2211124722013948
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Favine/CCDC3 deficiency accelerated atherosclerosis and thrombus formation is associated with decreased MEF2C-KLF2 pathway
    1
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      DOI: 10.1016/j.isci.2022.105252

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    ncbi.nlm.nih.gov/pmc/articles/PMC9587315/
  38. www.sciencedirect.com www.sciencedirect.com
    REM sleep-active hypothalamic neurons may contribute to hippocampal social-memory consolidation
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      DOI: 10.1016/j.neuron.2022.09.004

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    sciencedirect.com/science/article/pii/S0896627322008091
  39. journals.sagepub.com journals.sagepub.com
    Defibrinogenation Ameliorates Retinal Microgliosis and Inflammation in A CX3CR1-Independent Manner
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      DOI: 10.1177/17590914221131446

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    Comprehensive single-cell transcriptional profiling defines shared and unique epithelial injury responses during kidney fibrosis
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    Mapping brain gene coexpression in daytime transcriptomes unveils diurnal molecular networks and deciphers perturbation gene signatures
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    Gut-innervating nociceptors regulate the intestinal microbiota to promote tissue protection
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    Different priming states of synaptic vesicles underlie distinct release probabilities at hippocampal excitatory synapses
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    Nociceptor neurons direct goblet cells via a CGRP-RAMP1 axis to drive mucus production and gut barrier protection
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    Transcription factor RORα enforces stability of the Th17 cell effector program by binding to a Rorc cis-regulatory element
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    Lifespan changes in cannabinoid 1 receptor mRNA expression in the female C57BL/6J mouse brain
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    BefA, a microbiota-secreted membrane disrupter, disseminates to the pancreas and increases β cell mass
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    The gut peptide Reg3g links the small intestine microbiome to the regulation of energy balance, glucose levels, and gut function
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    Protocol for renal ischemia-reperfusion injury by flank incisions in mice
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    Neural signatures of auditory hypersensitivity following acoustic trauma
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  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reduced B-cell antigenicity of Omicron lowers host serologic response
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    Obesity caused by an OVOL2 mutation reveals dual roles of OVOL2 in promoting thermogenesis and limiting white adipogenesis
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    Differential plasticity and fate of brain-resident and recruited macrophages during the onset and resolution of neuroinflammation
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    PARP-inhibition reprograms macrophages toward an anti-tumor phenotype
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    Single-cell spatial transcriptomics reveals a dynamic control of metabolic zonation and liver regeneration by endothelial cell Wnt2 and Wnt9b
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    The primordial differentiation of tumor-specific memory CD8+ T cells as bona fide responders to PD-1/PD-L1 blockade in draining lymph nodes
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    Integrin-KCNB1 potassium channel complexes regulate neocortical neuronal development and are implicated in epilepsy
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    Calcineurin dephosphorylates topoisomerase IIβ and regulates the formation of neuronal-activity-induced DNA breaks
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  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of SRC-mediated integrin signaling in bone marrow niche enhances hematopoietic stem cell function
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    Histone methylation antagonism drives tumor immune evasion in squamous cell carcinomas
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    Mechanisms and significance of tissue-specific MICU regulation of the mitochondrial calcium uniporter complex
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    Modulation of 5-HT release by dynorphin mediates social deficits during opioid withdrawal
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    A Microarray Patch SARS-CoV-2 Vaccine Induces Sustained Antibody Responses and Polyfunctional Cellular Immunity
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    A non-canonical retina-ipRGCs-SCN-PVT visual pathway for mediating contagious itch behavior
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    Influenza A virus infection instructs hematopoiesis to megakaryocyte-lineage output
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  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phase Separation mediates NUP98 Fusion Oncoprotein Leukemic Transformation
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    Inhibition of inflammatory pain and cough by a novel charged sodium channel blocker
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    Regional heterogeneity in mitochondrial function underlies region specific vulnerability in human brain ageing: Implications for neurodegeneration
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    Essential role for epithelial HIF-mediated xenophagy in control of Salmonella infection and dissemination
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    Dopamine D2 receptors bidirectionally regulate striatal enkephalin expression: Implications for cocaine reward
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  77. Sep 2022
  78. aacrjournals.org aacrjournals.org
    Orthovoltage X-Rays Exhibit Increased Efficacy Compared with γ-Rays in Preclinical Irradiation
    1
    1. scibot 30 Sep 2022
      RRID:IMSR_JAX:000664

      DOI: 10.1158/0008-5472.CAN-22-0656

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    aacrjournals.org/cancerres/article/82/15/2678/707330/Orthovoltage-X-Rays-Exhibit-Increased-Efficacy
  79. www.sciencedirect.com www.sciencedirect.com
    Mucus-degrading Bacteroides link carbapenems to aggravated graft-versus-host disease
    1
    1. scibot 30 Sep 2022
      JAX:000664

      DOI: 10.1016/j.cell.2022.09.007

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    sciencedirect.com/science/article/pii/S0092867422011291
  80. www.sciencedirect.com www.sciencedirect.com
    Membrane-bound mRNA immunogens lower the threshold to activate HIV Env V2 apex-directed broadly neutralizing B cell precursors in humanized mice
    1
    1. scibot 30 Sep 2022
      JAX:000664

      DOI: 10.1016/j.immuni.2022.09.003

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    sciencedirect.com/science/article/pii/S1074761322004976
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MLKL protects against Clostridium perfringens infection by enhancing NLRP3 inflammasome-extracellular traps axis
    1
    1. scibot 30 Sep 2022
      RRID:IMSR_JAX:000664

      DOI: 10.1016/j.isci.2022.105121

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    ncbi.nlm.nih.gov/pmc/articles/PMC9515590/
  82. www.jneurosci.org www.jneurosci.org
    STAT1 contributes to microglial/macrophage inflammation and neurological dysfunction in a mouse model of traumatic brain injury
    1
    1. scibot 29 Sep 2022
      RRID:IMSR_JAX:000664

      DOI: 10.1523/JNEUROSCI.0682-22.2022

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    jneurosci.org/content/42/39/7466
  83. www.eneuro.org www.eneuro.org
    Application of 3D Printing Technology to Produce Hippocampal Customized Guide Cannulas
    1
    1. scibot 29 Sep 2022
      RRID:IMSR_JAX:000664

      DOI: 10.1523/ENEURO.0099-22.2022

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    eneuro.org/content/9/5/ENEURO.0099-22.2022
  84. www.sciencedirect.com www.sciencedirect.com
    Fasting-mimicking diet cycles reduce neuroinflammation to attenuate cognitive decline in Alzheimer’s models
    1
    1. scibot 29 Sep 2022
      JAX:000664

      DOI: 10.1016/j.celrep.2022.111417

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    sciencedirect.com/science/article/pii/S221112472201258X
  85. www.sciencedirect.com www.sciencedirect.com
    Motor cortical influence relies on task-specific activity covariation
    1
    1. scibot 29 Sep 2022
      RRID:IMSR_JAX:000664

      DOI: 10.1016/j.celrep.2022.111427

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    sciencedirect.com/science/article/pii/S2211124722012682
  86. www.sciencedirect.com www.sciencedirect.com
    Preparation of a murine oral palate wound healing model
    1
    1. scibot 28 Sep 2022
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      DOI: 10.1016/j.xpro.2022.101727

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    sciencedirect.com/science/article/pii/S2666166722006074
  87. www.sciencedirect.com www.sciencedirect.com
    Protocol to isolate and enrich mouse splenic naive CD4+ T cells for in vitro CD4+CD8αα+ cell induction
    1
    1. scibot 28 Sep 2022
      JAX:000664

      DOI: 10.1016/j.xpro.2022.101728

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  88. www.sciencedirect.com www.sciencedirect.com
    Enteric VIP-producing neurons maintain gut microbiota homeostasis through regulating epithelium fucosylation
    1
    1. scibot 24 Sep 2022
      000664

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    sciencedirect.com/science/article/pii/S1931312822004188
  89. www.sciencedirect.com www.sciencedirect.com
    Retinoid therapy restores eye-specific cortical responses in adult mice with retinal degeneration
    1
    1. scibot 24 Sep 2022
      RRID:IMSR_JAX:000664

      DOI: 10.1016/j.cub.2022.09.005

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    sciencedirect.com/science/article/pii/S096098222201449X
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterization of cellular senescence in aging skeletal muscle
    1
    1. scibot 23 Sep 2022
      JAX:000664

      DOI: 10.1038/s43587-022-00250-8

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    ncbi.nlm.nih.gov/pmc/articles/PMC9491365/
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Coxsackievirus B infections are common in Cystic Fibrosis and experimental evidence supports protection by vaccination
    1
    1. scibot 23 Sep 2022
      RRID:IMSR_JAX:000664

      DOI: 10.1016/j.isci.2022.105070

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  92. www.sciencedirect.com www.sciencedirect.com
    Mucosal plasma cells are required to protect the upper airway and brain from infection
    1
    1. scibot 23 Sep 2022
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      DOI: 10.1016/j.immuni.2022.08.017

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    sciencedirect.com/science/article/pii/S1074761322004113
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    Striatal dopamine explains novelty-induced behavioral dynamics and individual variability in threat prediction
    1
    1. scibot 22 Sep 2022
      RRID:IMSR_JAX:000664

      DOI: 10.1016/j.neuron.2022.08.022

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    sciencedirect.com/science/article/pii/S0896627322007589
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    Immune chromatin reader SP140 regulates microbiota and risk for inflammatory bowel disease
    1
    1. scibot 22 Sep 2022
      JAX:000664

      DOI: 10.1016/j.chom.2022.08.018

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    sciencedirect.com/science/article/pii/S1931312822004176
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inflammatory Monocytes Promote Granuloma-Mediated Control of Persistent Salmonella Infection
    1
    1. scibot 22 Sep 2022
      RRID:IMSR_JAX:000664

      DOI: 10.1128/iai.00070-22

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    ncbi.nlm.nih.gov/pmc/articles/PMC9022522/
  96. elifesciences.org elifesciences.org
    Crosstalk between AML and stromal cells triggers acetate secretion through the metabolic rewiring of stromal cells
    1
    1. scibot 22 Sep 2022
      RRID:IMSR_JAX:000664

      DOI: 10.7554/eLife.75908

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    elifesciences.org/articles/75908
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression
    1
    1. scibot 22 Sep 2022
      RRID:IMSR_JAX:000664

      DOI: 10.1136/gutjnl-2021-324994

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    ncbi.nlm.nih.gov/pmc/articles/PMC9271144/
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tyrosine 7.43 is important for mu-opioid receptor downstream signaling pathways activated by fentanyl
    1
    1. scibot 22 Sep 2022
      RRID:IMSR_JAX:000

      DOI: 10.3389/fphar.2022.919325

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    ncbi.nlm.nih.gov/pmc/articles/PMC9478952/
  99. www.sciencedirect.com www.sciencedirect.com
    Snail maintains the stem/progenitor state of skin epithelial cells and carcinomas through the autocrine effect of matricellular protein Mindin
    1
    1. scibot 21 Sep 2022
      Mouse: C57Bl6

      DOI: 10.1016/j.celrep.2022.111390

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    sciencedirect.com/science/article/pii/S221112472201227X
  100. www.sciencedirect.com www.sciencedirect.com
    Targeting the succinate receptor effectively inhibits periodontitis
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    1. scibot 21 Sep 2022
      000664

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    sciencedirect.com/science/article/pii/S2211124722012268
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    Microglial control of neuronal development via somatic purinergic junctions
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    1. scibot 21 Sep 2022
      RRID:IMSR_JAX:000664

      DOI: 10.1016/j.celrep.2022.111369

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    sciencedirect.com/science/article/pii/S2211124722012013
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    The escape of Candida albicans from macrophages is enabled by the fungal toxin candidalysin and two host cell death pathways
    1
    1. scibot 21 Sep 2022
      RRID:IMSR_JAX:000664

      DOI: 10.1016/j.celrep.2022.111374

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    sciencedirect.com/science/article/pii/S2211124722012062
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    Tissue-specific Grb10/Ddc insulator drives allelic architecture for cardiac development
    1
    1. scibot 21 Sep 2022
      RRID:IMSR_JAX:000664

      DOI: 10.1016/j.molcel.2022.08.021

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    sciencedirect.com/science/article/pii/S1097276522008103
  104. www.sciencedirect.com www.sciencedirect.com
    Dynamic reorganization of the cortico-basal ganglia-thalamo-cortical network during task learning
    1
    1. scibot 21 Sep 2022
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      DOI: 10.1016/j.celrep.2022.111394

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    sciencedirect.com/science/article/pii/S2211124722012311
  105. www.nature.com www.nature.com
    Macrophage-specific inhibition of the histone demethylase JMJD3 decreases STING and pathologic inflammation in diabetic wound repair
    1
    1. scibot 21 Sep 2022
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      DOI: 10.1038/s41423-022-00919-5

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    nature.com/articles/s41423-022-00919-5
  106. link.springer.com link.springer.com
    Sex-specific effects of maternal metformin intervention during glucose-intolerant obese pregnancy on body composition and metabolic health in aged mouse offspring
    1
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      RRID:IMSR_JAX:000664

      DOI: 10.1007/s00125-022-05789-0

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    link.springer.com/article/10.1007/s00125-022-05789-0
  107. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RIPOR2-mediated autophagy dysfunction is critical for aminoglycoside-induced hearing loss
    1
    1. scibot 16 Sep 2022
      Mouse: C57BL/6J

      DOI: 10.1016/j.devcel.2022.08.011

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    Neisseria species as pathobionts in bronchiectasis
    1
    1. scibot 16 Sep 2022
      Mouse: C57BL/6J

      DOI: 10.1016/j.chom.2022.08.005

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    Using mechanical homogenization to isolate microglia from mouse brain tissue to preserve transcriptomic integrity
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    1. scibot 16 Sep 2022
      C57BL/6J mice

      DOI: 10.1016/j.xpro.2022.101670

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  110. www.mdpi.com www.mdpi.com
    A Pharmacokinetic Dose-Optimization Study of Cabotegravir and Bictegravir in a Mouse Pregnancy Model
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      DOI: 10.3390/pharmaceutics14091761

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    mdpi.com/1999-4923/14/9/1761
  111. www.sciencedirect.com www.sciencedirect.com
    Inhibition of Th1 activation and differentiation by dietary guar gum ameliorates experimental autoimmune encephalomyelitis
    1
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      Mouse: C57BL/6J

      DOI: 10.1016/j.celrep.2022.111328

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    Posttranslational S-nitrosylation modification regulates HMGB1 secretion and promotes its proinflammatory and neurodegenerative effects
    1
    1. scibot 15 Sep 2022
      Mouse: C57BL/6J

      DOI: 10.1016/j.celrep.2022.111330

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    Medial orbitofrontal neurotrophin systems integrate hippocampal input into outcome-specific value representations
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    1. scibot 15 Sep 2022
      Mouse: C57BL/6

      DOI: 10.1016/j.celrep.2022.111334

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  114. www.sciencedirect.com www.sciencedirect.com
    Activation of VIP interneurons in the prefrontal cortex ameliorates neuropathic pain aversiveness
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      DOI: 10.1016/j.celrep.2022.111333

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  115. www.sciencedirect.com www.sciencedirect.com
    Pak2-mediated phosphorylation promotes RORγt ubiquitination and inhibits colonic inflammation
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      DOI: 10.1016/j.celrep.2022.111345

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    Hierarchical partner selection shapes rod-cone pathway specificity in the inner retina
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    Metronomic cyclophosphamide is more effective than a single dose in resistant tumours Cyclophosphamide depletes tumour infiltrating T regulatory cells and combined with anti-PD-1 therapy improves survival in murine neuroblastoma
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    Linking transcriptomes with morphological and functional phenotypes in mammalian retinal ganglion cells
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    Yin and Yang of Cannabinoid CB1 receptor: CB1 Deletion in Immune Cells Causes Exacerbation While CB1 Deletion in Non-immune Cells Attenuates Obesity
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      RRID:IMSR_JAX:000

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    Human gut microbiota stimulate defined innate immune responses that vary from phylum to strain
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    Uncompetitive, adduct-forming SARM1 inhibitors are neuroprotective in preclinical models of nerve injury and disease
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  124. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dendritic cell Piezo1 directs the differentiation of TH1 and Treg cells in cancer
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    Genetic- and diet-induced ω-3 fatty acid enrichment enhances TRPV4-mediated vasodilation in mice
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    ATF3 and CH25H regulate effector trogocytosis and anti-tumor activities of endogenous and immunotherapeutic cytotoxic T lymphocytes
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    Dopamine drives neuronal excitability via KCNQ channel phosphorylation for reward behavior
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  128. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anti-S100A4 antibody therapy is efficient in treating aggressive prostate cancer and reversing immunosuppression: Serum and biopsy S100A4 as clinical predictor
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    Molecular characteristics and laminar distribution of prefrontal neurons projecting to the mesolimbic system
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    NMDAR-dependent presynaptic homeostasis in adult hippocampus: Synapse growth and cross-modal inhibitory plasticity
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  132. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The parabigeminal nucleus is a source of “retinogeniculate replacement terminals” in mice that lack retinofugal input
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    A serotonergic axon-cilium synapse drives nuclear signaling to alter chromatin accessibility
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    PTP1B is an intracellular checkpoint that limits T cell and CAR T cell anti-tumor immunity
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    Mutant-IDH inhibits Interferon-TET2 signaling to promote immunoevasion and tumor maintenance in cholangiocarcinoma
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    Cellular barcoding of protozoan pathogens reveals the within-host population dynamics of Toxoplasma gondii host colonization
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    Convergent cerebrospinal fluid proteomes and metabolic ontologies in humans and animal models of Rett syndrome
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    Tonic activity in lateral habenula neurons acts as a neutral valence brake on reward-seeking behavior
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  140. Aug 2022
  141. www.sciencedirect.com www.sciencedirect.com
    Integrated single-cell transcriptomic analyses reveal that GPNMB-high macrophages promote PN-MES transition and impede T cell activation in GBM
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    RBM45 is an m6A-binding protein that affects neuronal differentiation and the splicing of a subset of mRNAs
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    B Cells Produce the Tissue-Protective Protein RELMα during Helminth Infection, which Inhibits IL-17 Expression and Limits Emphysema
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    Induction of tumor cell autosis by myxoma virus-infected CAR-T and TCR-T cells to overcome primary and acquired resistance
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    Toxic and Phenotypic Effects of AAV_Cre Used to Transduce Mesencephalic Dopaminergic Neurons
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    Divergent roles for the gut intraepithelial lymphocyte GLP-1R in control of metabolism, microbiota, and T cell-induced inflammation
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  147. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Paternal alcohol exposures program intergenerational hormetic effects on offspring fetoplacental growth
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    Protocol to assess the tolerogenic properties of adoptively transferred dendritic cells during murine experimental autoimmune encephalomyelitis
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  149. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Co-expression network analysis of human tau-transgenic mice reveals protein modules associated with tau-induced pathologies
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    Sensitivity to extracellular potassium underlies type-intrinsic differences in retinal ganglion cell excitability
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    Antibodies from primary humoral responses modulate recruitment of naive B cells during secondary responses
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    Fungal ablation and transplantation of specific fungal species into PDAC tumor-bearing mice
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    Hepatocyte Rap1a contributes to obesity- and statin-associated hyperglycemia
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    Lymphatic migration of unconventional T cells promotes site-specific immunity in distinct lymph nodes
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    Mitochondrial dynamics maintain muscle stem cell regenerative competence throughout adult life by regulating metabolism and mitophagy
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      RRID:IMSR_JAX:000664

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    Pancreas agenesis mutations disrupt a lead enhancer controlling a developmental enhancer cluster
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    Air-liquid organotypic assays to investigate cellular crosstalk in the tumor microenvironment of cancer cells
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    Glutamine metabolism modulates chondrocyte inflammatory response
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  159. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Serotonin Receptor 5-HT2A Regulates TrkB Receptor Function in Heteroreceptor Complexes
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      RRID:IMSR_JAX:000664

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    Taste Receptor Activation in Tracheal Brush Cells by Denatonium Modulates ENaC Channels via Ca2+, cAMP and ACh
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    Sustained deep-tissue voltage recording using a fast indicator evolved for two-photon microscopy
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    sciencedirect.com/science/article/pii/S0092867422009163
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    Protocol to visualize CD11c+ cells in atherosclerosis using LacZ reporter mice
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      RRID:IMSR_JAX:000664

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    A WISP1 antibody inhibits MRTF signaling to prevent the progression of established liver fibrosis
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    Enhanced excitability of the hippocampal CA2 region and its contribution to seizure activity in a mouse model of temporal lobe epilepsy
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    Mitochondrial microproteins link metabolic cues to respiratory chain biogenesis
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    STK25 inhibits PKA signaling by phosphorylating PRKAR1A
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    Stromal remodeling regulates dendritic cell abundance and activity in the tumor microenvironment
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    The mitochondrial calcium uniporter engages UCP1 to form a thermoporter that promotes thermogenesis
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    GTSF1 accelerates target RNA cleavage by PIWI-clade Argonaute proteins
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    Dysbiosis in imiquimod-induced psoriasis alters gut immunity and exacerbates colitis development
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    Advanced paternal age diversifies individual trajectories of vocalization patterns in neonatal mice
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    Epigenetic reader SP140 loss of function drives Crohn’s disease due to uncontrolled macrophage topoisomerases
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    Apolipoprotein E4 impairs the response of neurodegenerative retinal microglia and prevents neuronal loss in glaucoma
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      JAX:000664

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    Molecular and histological correlates of cognitive decline across age in male C57BL/6J mice
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      DOI: 10.1002/brb3.2736

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    Striatonigrostriatal circuit architecture for disinhibition of dopamine signaling
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      RRID:IMSR_JAX:000

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    NMDA receptor-targeted enrichment of CaMKIIα improves fear memory
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    Protocol to analyze antitumor immunity of orthotopic injection and spontaneous murine high-grade glioma models using flow cytometry and single-cell RNA sequencing
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    Neuroinflammatory disease disrupts the blood-CNS barrier via crosstalk between proinflammatory and endothelial-to-mesenchymal-transition signaling
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      The Jackson LaboratoryStrain: 000664

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  179. journals.physiology.org journals.physiology.org
    SLAMF1 is expressed and secreted by hepatocytes and the liver in nonalcoholic fatty liver disease
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    Single-cell transcriptome analysis of regenerating RGCs reveals potent glaucoma neural repair genes
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    Heritable vaginal bacteria influence immune tolerance and relate to early-life markers of allergic sensitization in infancy
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      Jackson LaboratoriesStock# 000664

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    Longitudinal Tracing of Lyssavirus Infection in Mice via In Vivo Bioluminescence Imaging
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  183. alz-journals.onlinelibrary.wiley.com alz-journals.onlinelibrary.wiley.com
    Prophylactic evaluation of verubecestat on disease- and symptom-modifying effects in 5XFAD mice
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      JAX stock #000664

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    Control of fear by discrete prefrontal GABAergic populations encoding valence-specific information
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    Combination of Radiotherapy and Complement C3a Inhibition Potentiates Natural Killer cell Functions Against Pancreatic Cancer
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      JAX:000664

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    Wound healing in aged skin exhibits systems-level alterations in cellular composition and cell-cell communication
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    Adenosine metabolized from extracellular ATP promotes type 2 immunity through triggering A2BAR signaling in intestinal epithelial cells
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    Prenatal environmental stressors impair postnatal microglia function and adult behavior in males
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    METTL14-dependent m6A modification controls iNKT cell development and function
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  190. www.jimmunol.org www.jimmunol.org
    Spinal Cord Injury Impairs Lung Immunity in Mice
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      The Jackson Laboratory (strain no. 000664)

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    Aberrant iron distribution via hepatocyte-stellate cell axis drives liver lipogenesis and fibrosis
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    An inhibitory brainstem input to dopamine neurons encodes nicotine aversion
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    Therapeutic deep brain stimulation disrupts movement-related subthalamic nucleus activity in parkinsonian mice
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    The endoplasmic reticulum membrane complex promotes proteostasis of GABAA receptors
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    Dynamic control of visually guided locomotion through corticosubthalamic projections
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    Lung fibroblasts facilitate pre-metastatic niche formation by remodeling the local immune microenvironment
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    Chemokine CXCL10 Modulates the Tumor Microenvironment of Fibrosis-Associated Hepatocellular Carcinoma
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    Activation of NLRP3 Is Required for a Functional and Beneficial Microglia Response after Brain Trauma
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