When Ishtar heard this she fell into a bitter rage, she went up to high heaven.
Nature can be dangerous especially for those who travel in the wild. This is also a comparison to the Goddess Ishtar. She is powerful and can be an agent of destruction. When Gilgamesh not recognizing this aspect of the feminine caused destruction in his life. The death of Enkidu was the result of Gilgamesh rejecting her temptations.