512 Matching Annotations
  1. Jan 2024
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    The male pachynema-specific protein MAPS drives phase separation in vitro and regulates sex body formation and chromatin behaviors in vivo
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    sciencedirect.com/science/article/pii/S2211124723016625
  3. Dec 2023
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    MEK-inhibitors decrease Nfix in muscular dystrophy but induce unexpected calcifications, partially rescued with Cyanidin diet
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    sciencedirect.com/science/article/pii/S2589004223027736
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    FEZ1 participates in human embryonic brain development by modulating neuronal progenitor subpopulation specification and migration
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    sciencedirect.com/science/article/pii/S2589004223025749
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel patient-derived meningioma spheroid model as a tool to study and treat epithelial-to-mesenchymal transition (EMT) in meningiomas
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    ncbi.nlm.nih.gov/pmc/articles/PMC10725030/
  7. journals.plos.org journals.plos.org
    The circadian regulator PER1 promotes cell reprogramming by inhibiting inflammatory signaling from macrophages
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    journals.plos.org/plosbiology/article
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epigenetic priming of an epithelial enhancer by p63 and CTCF controls expression of a skin-restricted gene XP33
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    ncbi.nlm.nih.gov/pmc/articles/PMC10709559/
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The role of hypoxia and radiation in developing a CTCs-like phenotype in murine osteosarcoma cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10687637/
  10. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Leakage beyond the primary lesion: A temporal analysis of cerebrovascular dysregulation at sites of hippocampal secondary neurodegeneration following cortical photothrombotic stroke
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    onlinelibrary.wiley.com/doi/10.1111/jnc.16008
  11. Nov 2023
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    The γ-secretase substrate proteome and its role in cell signaling regulation
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    sciencedirect.com/science/article/pii/S1097276523008663
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    Coexistence of apoptosis, pyroptosis, and necroptosis pathways in Celiac Disease
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    dx.doi.org/10.1093/cei/uxad082
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    Autophagy-mediated control of ribosome homeostasis in oncogene-induced senescence
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    sciencedirect.com/science/article/pii/S2211124723013931
  15. aacrjournals.org aacrjournals.org
    MRTX1719 Is an MTA-Cooperative PRMT5 Inhibitor That Exhibits Synthetic Lethality in Preclinical Models and Patients with MTAP-Deleted Cancer
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    aacrjournals.org/cancerdiscovery/article/13/11/2412/729848/MRTX1719-Is-an-MTA-Cooperative-PRMT5-Inhibitor
  16. Oct 2023
  17. link.springer.com link.springer.com
    Serotonin 2C receptors are also important in head-twitch responses in male mice
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    link.springer.com/article/10.1007/s00213-023-06482-9
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    Effector memory T cells induce innate inflammation by triggering DNA damage and a non-canonical STING pathway in dendritic cells
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    sciencedirect.com/science/article/pii/S2211124723011920
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    Distinct mechanisms drive sequential internalization and degradation of GABAARs during global ischemia and reperfusion injury
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    cell.com/iscience/abstract/S2589-0042(23)02138-7
  20. 52.53.155.43 52.53.155.43
    s41586-023-06657-6_reference-html.html
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  21. Sep 2023
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Generation of a human Tropomyosin 1 knockout iPSC line
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    ncbi.nlm.nih.gov/pmc/articles/PMC10507314/
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone bivalency regulates the timing of cerebellar granule cell development
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    ncbi.nlm.nih.gov/pmc/articles/PMC10499015/
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    Base editing corrects the common Salla disease SLC17A5 c.115C>T variant
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    sciencedirect.com/science/article/pii/S2162253123002354
  25. Aug 2023
  26. www.science.org www.science.org
    A virally encoded GPCR drives glioblastoma through feed-forward activation of the SK1-S1P1 signaling axis
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    science.org/doi/10.1126/scisignal.ade6737
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    A Zpr1 co-chaperone mediates folding of eukaryotic translation elongation factor 1A via a GTPase cycle
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    sciencedirect.com/science/article/abs/pii/S1097276523006019
  28. 52.53.155.43 52.53.155.43
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    FASN deficiency induces a cytosol-to-mitochondria citrate flux to mitigate detachment-induced oxidative stress
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  30. Jul 2023
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    5‐Hydroxymethylfurfural reduces skeletal muscle superoxide production and modifies force production in rats exposed to hypobaric hypoxia
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    ncbi.nlm.nih.gov/pmc/articles/PMC10368650/
  32. 52.53.155.43 52.53.155.43
    Generation of a human Tropomyosin 1 knockout iPSC line
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    Marchf6 E3 ubiquitin ligase critically regulates endoplasmic reticulum stress, ferroptosis, and metabolic homeostasis in POMC neurons
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    The integrated stress response effector ATF4 is an obligatory metabolic activator of NRF2
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  35. Jun 2023
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    Chemical genomics reveals targetable programs of human cancers rooted in pluripotency
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    sciencedirect.com/science/article/pii/S2451945623001587
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Uterine-specific Ezh2 deletion enhances stromal cell senescence and impairs placentation, resulting in pregnancy loss
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    ncbi.nlm.nih.gov/pmc/articles/PMC10285549/
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    MCT4-dependent lactate secretion suppresses antitumor immunity in LKB1-deficient lung adenocarcinoma
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    sciencedirect.com/science/article/pii/S1535610823001824
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    Characterization of Hofbauer cell polarization and VEGF localization in human term placenta from active and inactive pregnant individuals
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    physoc.onlinelibrary.wiley.com/doi/10.14814/phy2.15741
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    The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins
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    sciencedirect.com/science/article/pii/S2211124723005909
  41. May 2023
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    Protocol for biallelic tagging of an endogenous gene using CRISPR-Cas9 in human cells
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    sciencedirect.com/science/article/pii/S2666166723002538
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitofusin 2 sustains the axonal mitochondrial network to support presynaptic Ca2+ homeostasis and the synaptic vesicle cycle in rat hippocampal axons
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    ncbi.nlm.nih.gov/pmc/articles/PMC10175236/
  44. www.nature.com www.nature.com
    Tumor treating fields affect mesothelioma cell proliferation by exerting histotype-dependent cell cycle checkpoint activations and transcriptional modulations
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    nature.com/articles/s41419-022-05073-4
  45. Apr 2023
  46. www.sciencedirect.com www.sciencedirect.com
    A hyper-quiescent chromatin state formed during aging is reversed by regeneration
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    sciencedirect.com/science/article/pii/S1097276523002496
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    Changes in nascent chromatin structure regulate activation of the pro-fibrotic transcriptome and myofibroblast emergence in organ fibrosis
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    sciencedirect.com/science/article/pii/S2589004223006478
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Particulate matter exposure and chronic cerebral hypoperfusion promote oxidative stress and induce neuronal and oligodendrocyte apoptosis in male mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC10107949/
  49. 52.53.155.43 52.53.155.43
    Boosting BDNF in muscle rescues impaired in vivo axonal transport in a mouse model of DI-CMTC peripheral neuropathy
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    PYHIN protein IFI207 regulates cytokine transcription and IRF7 and contributes to the establishment of K. pneumoniae infection
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    sciencedirect.com/science/article/pii/S2211124723003522
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    VGLL2-NCOA2 leverages developmental programs for pediatric sarcomagenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10054615/
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    The mitochondrial protease OMA1 acts as a metabolic safeguard upon nuclear DNA damage
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    sciencedirect.com/science/article/pii/S2211124723003431
  53. Mar 2023
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NLRC5 affects diet-induced adiposity in female mice and co-regulates peroxisome proliferator-activated receptor PPARγ target genes
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    ncbi.nlm.nih.gov/pmc/articles/PMC10034470/
  55. 52.53.155.43 52.53.155.43
    A high-sucrose diet exacerbates the left ventricular phenotype in a high fat-fed streptozotocin rat model of diabetic cardiomyopathy
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    FAM193A is a positive regulator of p53 activity
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    sciencedirect.com/science/article/pii/S2211124723002413
  57. Feb 2023
  58. www.sciencedirect.com www.sciencedirect.com
    Bullatine A Has an Antidepressant Effect in Chronic Social Defeat Stress Mice; Implication of Microglial Inflammasome
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    sciencedirect.com/science/article/pii/S0361923023000497
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    TGF-β in the microenvironment induces a physiologically occurring immune-suppressive senescent state
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    Cofilin promotes tau pathology in Alzheimer’s disease
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    PHGDH-mediated endothelial metabolism drives glioblastoma resistance to chimeric antigen receptor T cell immunotherapy
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    sciencedirect.com/science/article/pii/S1550413123000104
  62. www.mdpi.com www.mdpi.com
    CXXC5 Mediates DHT-Induced Androgenetic Alopecia via PGD2
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    mdpi.com/2073-4409/12/4/555
  63. www.sciencedirect.com www.sciencedirect.com
    Human IRF1 governs macrophagic IFN-γ immunity to mycobacteria
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    sciencedirect.com/science/article/pii/S0092867422015811
  64. www.sciencedirect.com www.sciencedirect.com
    RIF1 suppresses the formation of single-stranded ultrafine anaphase bridges via protein phosphatase 1
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    sciencedirect.com/science/article/pii/S2211124723000438
  65. Jan 2023
  66. www.sciencedirect.com www.sciencedirect.com
    A circadian clock translational control mechanism targets specific mRNAs to cytoplasmic messenger ribonucleoprotein granules
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  67. link.springer.com link.springer.com
    Abl2 Kinase Differentially Regulates iGluRs Current Activity and Synaptic Localization
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    link.springer.com/article/10.1007/s10571-023-01317-9
  68. www.nature.com www.nature.com
    Hippocampal dentate gyri proteomics reveals Wnt signaling involvement in the behavioral impairment in the THRSP-overexpressing ADHD mouse model
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    nature.com/articles/s42003-022-04387-5
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neoadjuvant chemotherapy is associated with an altered metabolic profile and increased cancer stemness in patients with pancreatic ductal adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9812839/
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Early alveolar epithelial cell necrosis is a potential driver of COVID-19-induced acute respiratory distress syndrome
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    ncbi.nlm.nih.gov/pmc/articles/PMC9722615/
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    Potent ClpP agonists with anticancer properties bind with improved structural complementarity and alter the mitochondrial N-terminome
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    sciencedirect.com/science/article/pii/S0969212622004889
  72. Dec 2022
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Allosteric Inhibition of c-Abl to Induce Unfolded Protein Response and Cell Death in Multiple Myeloma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9786043/
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    In vitro-derived medium spiny neurons recapitulate human striatal development and complexity at single-cell resolution
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    sciencedirect.com/science/article/pii/S2667237522002697
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    Renal angiotensin I-converting enzyme-deficient mice are protected against aristolochic acid nephropathy
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    link.springer.com/article/10.1007/s00424-022-02779-4
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    Vibrio parahaemolyticus prey targeting requires autoproteolysis-triggered dimerization of the type VI secretion system effector RhsP
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    sciencedirect.com/science/article/pii/S2211124722016102
  78. Nov 2022
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    Branched-chain amino acid catabolism breaks glutamine addiction to sustain hepatocellular carcinoma progression
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    Antiviral function and viral antagonism of the rapidly evolving dynein activating adaptor NINL
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    ncbi.nlm.nih.gov/pmc/articles/PMC9651953/
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PGC-1α in the myofibers regulates the balance between myogenic and adipogenic progenitors affecting muscle regeneration
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    ncbi.nlm.nih.gov/pmc/articles/PMC9663886/
  82. onlinelibrary.wiley.com onlinelibrary.wiley.com
    hnRNP A1 dysfunction in oligodendrocytes contributes to the pathogenesis of multiple sclerosis
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    onlinelibrary.wiley.com/doi/10.1002/glia.24300
  83. www.researchsquare.com www.researchsquare.com
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    Angiotensin II regulates mitochondrial mTOR pathway activity dependent on acyl CoA synthetase 4 in adrenocortical cells
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    academic.oup.com/endo/article-abstract/163/12/bqac170/6763139
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    Nuclear stabilization of p53 requires a functional nucleolar surveillance pathway
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    sciencedirect.com/science/article/pii/S2211124722014322
  86. Oct 2022
  87. academic.oup.com academic.oup.com
    The mineralocorticoid receptor functions as a key glucose regulator in the skeletal muscle of zebrafish
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    academic.oup.com/endo/article/163/11/bqac149/6679268
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    Co-alterations of circadian clock gene transcripts in human placenta in preeclampsia
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    nature.com/articles/s41598-022-22507-3
  89. Sep 2022
  90. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Meprin β expression modulates the interleukin-6 mediated JAK2-STAT3 signaling pathway in ischemia/reperfusion-induced kidney injury
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    physoc.onlinelibrary.wiley.com/doi/10.14814/phy2.15468
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    Stress-inducible phosphoprotein 1 (HOP/STI1/STIP1) regulates the accumulation and toxicity of α-synuclein in vivo
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    link.springer.com/article/10.1007/s00401-022-02491-8
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    Genetic- and diet-induced ω-3 fatty acid enrichment enhances TRPV4-mediated vasodilation in mice
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    sciencedirect.com/science/article/pii/S2211124722011305
  93. Aug 2022
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GSK3β Inhibition Is the Molecular Pivot That Underlies the Mir-210-Induced Attenuation of Intrinsic Apoptosis Cascade during Hypoxia
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    ncbi.nlm.nih.gov/pmc/articles/PMC9409400/
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Septin7 is indispensable for proper skeletal muscle architecture and function
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  96. Jul 2022
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    GPCR kinases generate an APH1A phosphorylation barcode to regulate amyloid-β generation
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    Ubiquitin profiling of lysophagy identifies actin stabilizer CNN2 as a target of VCP/p97 and uncovers a link to HSPB1
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  99. Jun 2022
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    Prkn knockout mice show autistic-like behaviors and aberrant synapse formation
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    sciencedirect.com/science/article/pii/S2589004222008458
  101. www.sciencedirect.com www.sciencedirect.com
    UBP12 and UBP13 deubiquitinases destabilize the CRY2 blue light receptor to regulate Arabidopsis growth
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    sciencedirect.com/science/article/pii/S0960982222008491
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ANGT_HUMAN[448–462], an Anorexigenic Peptide Identified using Plasma Peptidomics
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    ncbi.nlm.nih.gov/pmc/articles/PMC9184509/
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    The focal adhesion protein β-parvin controls cardiomyocyte shape and sarcomere assembly in response to mechanical load
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    sciencedirect.com/science/article/pii/S0960982222008508
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    Cryo-EM structure of the entire FtsH-HflKC AAA protease complex
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    Unexpected short- and long-term effects of chronic adolescent HU-210 exposure on emotional behavior
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    sciencedirect.com/science/article/pii/S0028390822002143
  106. May 2022
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  125. Feb 2022
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  216. Apr 2021
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    Mitochondria Define Intestinal Stem Cell Differentiation Downstream of a FOXO/Notch Axis
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  220. Feb 2021
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  227. Nov 2020
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