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  1. Sep 2023
  2. www.sciencedirect.com www.sciencedirect.com
    Myeloid BAF60a deficiency alters metabolic homeostasis and exacerbates atherosclerosis
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    sciencedirect.com/science/article/pii/S221112472301183X
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    Lysosomal cyst(e)ine storage potentiates tolerance to oxidative stress in cancer cells
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    sciencedirect.com/science/article/pii/S1097276523006950
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    Control of mitophagy initiation and progression by the TBK1 adaptors NAP1 and SINTBAD
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    1. scibot 30 Sep 2023
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      DOI: 10.1101/2023.09.25.559255

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    biorxiv.org/content/10.1101/2023.09.25.559255v1
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    Low glucose metabolite 3-phosphoglycerate switches PHGDH from serine synthesis to p53 activation to control cell fate
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    nature.com/articles/s41422-023-00874-4
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    Identification of genes required for Plasmodium gametocyte-to-sporozoite development in the mosquito vector
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    sciencedirect.com/science/article/pii/S1931312823003359
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    E2 enzyme Bruce negatively regulates Hippo signaling through POSH-mediated expanded degradation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10497580/
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    TMEM127 suppresses tumor development by promoting RET ubiquitination, positioning, and degradation
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    sciencedirect.com/science/article/pii/S2211124723010811
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    Activation of AKT induces EZH2-mediated β-catenin trimethylation in colorectal cancer
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10475482/
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    Heterogeneous receptor expression underlies non-uniform peptidergic modulation of olfaction in Drosophila
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    ncbi.nlm.nih.gov/pmc/articles/PMC10465596/
  11. Aug 2023
  12. www.science.org www.science.org
    In silico protein interaction screening uncovers DONSON’s role in replication initiation
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    1. scibot 29 Aug 2023
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    GSK3 and lamellipodin balance lamellipodial protrusions and focal adhesion maturation in mouse neural crest migration
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    sciencedirect.com/science/article/pii/S2211124723010410
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    Hypermethylation of RNF125 promotes autophagy-induced oxidative stress in asthma by increasing HMGB1 stability
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    1. scibot 26 Aug 2023
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    ncbi.nlm.nih.gov/pmc/articles/PMC10432822/
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    TRAF7 is an essential regulator of blood vessel integrity during mouse embryonic and neonatal development
    1
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  16. 52.53.155.43 52.53.155.43
    Loss of CtBP2 may be a mechanistic link between metabolic derangements and progressive impairment of pancreatic β cell function
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  17. 52.53.155.43 52.53.155.43
    NFYC-37 promotes tumor growth by activating the mevalonate pathway in bladder cancer
    2
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    52.53.155.43/eb7aace05cf7a189f4453bfbeb3bcf344412f769/mmc4-html.html
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    A novel immune modulator IM33 mediates a glia-gut-neuronal axis that controls lifespan
    1
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    sciencedirect.com/science/article/abs/pii/S0896627323005433
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    5-HT1A and 5-HT2B receptor interaction and co-clustering regulate serotonergic neuron excitability. 5-HT receptor cross-talks shape 5-HT neuron activity
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    Two RNA-binding proteins mediate the sorting of miR223 from mitochondria into exosomes
    1
    1. scibot 10 Aug 2023
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      DOI: 10.7554/eLife.85878

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    Genetic reporter for live tracing fluid flow forces during cell fate segregation in mouse blastocyst development
    1
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    sciencedirect.com/science/article/pii/S1934590923002485
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    O-GlcNAcylation of Raptor transduces glucose signals to mTORC1
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    sciencedirect.com/science/article/abs/pii/S1097276523005269
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    Catalytic inhibitor of Protein Phosphatase 5 activates the extrinsic apoptotic pathway by disrupting complex II in kidney cancer
    1
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    sciencedirect.com/science/article/abs/pii/S2451945623002064
  24. Jul 2023
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    Condensate cooperativity underlies transgenerational gene silencing
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    sciencedirect.com/science/article/pii/S2211124723008707
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    CCDC176 stabilizes microtubule doublets 1 and 9 to ensure proper sperm movement
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    sciencedirect.com/science/article/pii/S0960982223008655
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    SMYD3 represses tumor-intrinsic interferon response in HPV-negative squamous cell carcinoma of the head and neck
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    Loss of SYNCRIP unleashes APOBEC-driven mutagenesis, tumor heterogeneity, and AR-targeted therapy resistance in prostate cancer
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    sciencedirect.com/science/article/pii/S1535610823002350
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    Orphan quality control shapes network dynamics and gene expression
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  30. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Cheng - Pharmacological targeting of Axin2 suppresses cell growth and metastasis in-html.html
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      DOI: 10.1111/bph.16193

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    52.53.155.43/51180316abfac9593501c4c683749a3ad6cad477/British J Pharmacology - 2023 - Cheng - Pharmacological targeting of Axin2 suppresses cell growth and metastasis in-html.html
  31. www.nature.com www.nature.com
    Adeno-associated viral vectors for functional intravenous gene transfer throughout the non-human primate brain
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    nature.com/articles/s41565-023-01419-x
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    Distinct layers of BRD4-PTEFb reveal bromodomain-independent function in transcriptional regulation
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    sciencedirect.com/science/article/abs/pii/S1097276523005087
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    Enhanced bypass of PD-L1 translation reduces the therapeutic response to mTOR kinase inhibitors
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  34. www.biorxiv.org www.biorxiv.org
    Ninein domains required for its localization, association with partners dynein and ensconsin, and microtubule organization
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      DOI: 10.1101/2023.06.22.546109

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    biorxiv.org/content/10.1101/2023.06.22.546109v2
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    The neural basis of resting-state fMRI functional connectivity in fronto-limbic circuits revealed by chemogenetic manipulation
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    biorxiv.org/content/10.1101/2023.06.21.545778v1
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    Targeted high-throughput mutagenesis of the human spliceosome reveals its in vivo operating principles
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    Chromatin regulation of transcriptional enhancers and cell fate by the Sotos syndrome gene NSD1
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    TONSOKU is required for the maintenance of repressive chromatin modifications in Arabidopsis
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    sciencedirect.com/science/article/pii/S2211124723007490
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    Generation of host-directed and virus-specific antivirals using targeted protein degradation promoted by small molecules and viral RNA mimics
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    sciencedirect.com/science/article/pii/S1931312823002238
  40. Jun 2023
  41. 52.53.155.43 52.53.155.43
    TOPK mediates immune evasion of Renal Cell Carcinoma via upregulating the expression of PD-L1
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    Ubiquitin ligase and signalling hub MYCBP2 is required for efficient EPHB2 tyrosine kinase receptor function
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    biorxiv.org/content/10.1101/2023.06.12.544638v3
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    Modulation of cellular metabolism by protein crotonylation regulates pancreatic cancer progression
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    The Transmembrane Protein TM4SF3 Interacts with AR and AR-V7 and is Recruited to AR Target Genes
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    Homeostatic Regulation of Seizure Susceptibility and Cognitive Function by ER Quality Controller Derlin-1 through Maintenance of Adult Neurogenesis
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    PPDPF suppresses the development of hepatocellular carcinoma through TRIM21-mediated ubiquitination of RIPK1
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    Behavioral circatidal rhythms require Bmal1 in Parhyale hawaiensis
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    Proximity labeling reveals OTUD3 as a DNA-binding deubiquitinase of cGAS
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    Integrated Genomic Analysis Identifies UBTF Tandem Duplications as a Recurrent Lesion in Pediatric Acute Myeloid Leukemia
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    Cytosolic DNA sensing by cGAS/STING promotes TRPV2-mediated Ca2+ release to protect stressed replication forks
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    A central role for regulated protein stability in the control of TFE3 and MITF by nutrients
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    Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis
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    PALI1 promotes tumor growth through competitive recruitment of PRC2 to G9A-target chromatin for dual epigenetic silencing
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    The insulin and IGF signaling pathway sustains breast cancer stem cells by IRS2/PI3K-mediated regulation of MYC
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    Adult newborn granule cells confer emotional state–dependent adaptability in memory retrieval
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    The oncogenic JAG1 intracellular domain is a transcriptional cofactor that acts in concert with DDX17/SMAD3/TGIF2
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    Dynamic quality control machinery that operates across compartmental borders mediates the degradation of mammalian nuclear membrane proteins
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    Development of single-molecule ubiquitination mediated fluorescence complementation to visualize protein ubiquitination dynamics in dendrites
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    TIF1γ inhibits lung adenocarcinoma EMT and metastasis by interacting with the TAF15/TBP complex
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    Inhibition of the CtBP complex and FBXO11 enhances MHC class II expression and anti-cancer immune responses
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    A nuclear cAMP microdomain suppresses tumor growth by Hippo pathway inactivation
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    Endogenous transcripts direct microRNA degradation in Drosophila, and this targeted degradation is required for proper embryonic development
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    The neutralization of B.1.617.1 and B.1.1.529 sera from convalescent patients and BBIBP-CorV vaccines
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    AgRP neuronal silencing overcomes delayed puberty in neonatally underfed male mice
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    Posttranslational S-nitrosylation modification regulates HMGB1 secretion and promotes its proinflammatory and neurodegenerative effects
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    Generation of knock-in degron tags for endogenous proteins in mice using the dTAG system
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    A biochemical reconstitution approach to identify autophagy receptors for aggrephagy in mammalian cells
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    Increased glucose metabolism in TAMs fuels O-GlcNAcylation of lysosomal Cathepsin B to promote cancer metastasis and chemoresistance
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    Lipophorin receptors regulate mushroom body development and complex behaviors in Drosophila
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    RBM45 is an m6A-binding protein that affects neuronal differentiation and the splicing of a subset of mRNAs
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  184. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    trim-21 promotes proteasomal degradation of CED-1 for apoptotic cell clearance in C. elegans
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    Chromatin-bound RB targets promoters, enhancers, and CTCF-bound loci and is redistributed by cell-cycle progression
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    Tripartite Motif 38 Attenuates Cardiac Fibrosis after Myocardial Infarction by Suppressing TAK1 Activation via TAB2/3 Degradation
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    Negative autoregulation mitigates collateral RNase activity of repeat-targeting CRISPR-Cas13d in mammalian cells
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    The mitochondrial calcium uniporter engages UCP1 to form a thermoporter that promotes thermogenesis
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    EZH2 T367 phosphorylation activates p38 signaling through lysine methylation to promote breast cancer progression
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    Humanized substitutions of Vmat1 in mice alter amygdala-dependent behaviors associated with the evolution of anxiety
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    LGP2 is essential for zebrafish survival through dual regulation of IFN antiviral response
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    Optical Clearing and 3D Analysis Optimized for Mouse and Human Pancreata
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    Cxcr4 and Ackr3 regulate allocation of caudal ganglionic eminence-derived interneurons to superficial cortical layers
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    A dRASSF-STRIPAK-Imd-JAK/STAT axis controls antiviral immune response in Drosophila
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    Membrane Targeting and GTPase Activity of Rab7 Are Required for Its Ubiquitination by RNF167
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    GPCR kinases generate an APH1A phosphorylation barcode to regulate amyloid-β generation
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    The testis-specific E3 ubiquitin ligase RNF133 is required for fecundity in mice
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    Resolution of R-loops by topoisomerase III-β (TOP3B) in coordination with the DEAD-box helicase DDX5
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    A specialized Hsp90 co-chaperone network regulates steroid hormone receptor response to ligand
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    Molecular mechanism of S-adenosylmethionine sensing by SAMTOR in mTORC1 signaling
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    LncNSPL facilitates influenza A viral immune escape by restricting TRIM25-mediated K63-linked RIG-I ubiquitination
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    Neural network organization for courtship-song feature detection in Drosophila
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  210. Jun 2022
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