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Oct 2022
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Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer

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1. scibot 23 Oct 2022
  
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  DOI: 10.1016/j.molcel.2022.09.034
  
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sciencedirect.com/science/article/pii/S1097276522009558
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p300/CBP sustains Polycomb silencing by non-enzymatic functions

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  DOI: 10.1016/j.molcel.2022.09.005
  
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sciencedirect.com/science/article/pii/S1097276522008942
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Cross-lineage potential of Ascl1 uncovered by comparing diverse reprogramming regulatomes

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  DOI: 10.1016/j.stem.2022.09.006
  
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sciencedirect.com/science/article/pii/S1934590922003836
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Dissection of the MEF2D-IRF8 transcriptional circuit dependency in acute myeloid leukemia

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  DOI: 10.1016/j.isci.2022.105139
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9526175/
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A cis-regulatory lexicon of DNA motif combinations mediating cell-type-specific gene regulation

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  DOI: 10.1016/j.xgen.2022.100191
  
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sciencedirect.com/science/article/pii/S2666979X22001409
Sep 2022
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Single-cell sequencing reveals activation of core transcription factors in PRC2-deficient malignant peripheral nerve sheath tumor

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  DOI: 10.1016/j.celrep.2022.111363
  
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sciencedirect.com/science/article/pii/S2211124722011950
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Balance between immunoregulatory B cells and plasma cells drives pancreatic tumor immunity

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  DOI: 10.1016/j.xcrm.2022.100744
  
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STAG2 promotes the myelination transcriptional program in oligodendrocytes

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1. scibot 08 Sep 2022
  
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  DOI: 10.7554/eLife.77848
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9439679/
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Intracellular cholesterol pools regulate oncogenic signaling and epigenetic circuitries in Early T-cell Precursor Acute Lymphoblastic Leukemia

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1. scibot 02 Sep 2022
  
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  DOI: 10.1158/2159-8290.CD-21-0551
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8904296/
Aug 2022
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The Il6 -39kb enhancer containing clustered GATA2- and PU.1- binding sites is essential for Il6 expression in murine mast cells

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1. scibot 31 Aug 2022
  
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  DOI: 10.1016/j.isci.2022.104942
  
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sciencedirect.com/science/article/pii/S2589004222012147
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Pancreas agenesis mutations disrupt a lead enhancer controlling a developmental enhancer cluster

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1. scibot 23 Aug 2022
  
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  DOI: 10.1016/j.devcel.2022.07.014
  
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sciencedirect.com/science/article/pii/S1534580722005317
Jul 2022
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Single-cell multiome of the human retina and deep learning nominate causal variants in complex eye diseases

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1. scibot 28 Jul 2022
  
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  DOI: 10.1016/j.xgen.2022.100164
  
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sciencedirect.com/science/article/pii/S2666979X22001069
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Transcription factors TCF-1 and GATA3 are key factors for the epigenetic priming of early innate lymphoid progenitors toward distinct cell fates

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1. scibot 27 Jul 2022
  
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  DOI: 10.1016/j.immuni.2022.06.019
  
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sciencedirect.com/science/article/pii/S1074761322002928
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Induction of senescence upon loss of the Ash2l core subunit of H3K4 methyltransferase complexes

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1. scibot 13 Jul 2022
  
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  DOI: 10.1093/nar/gkac591
  
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academic.oup.com/nar/advance-article/doi/10.1093/nar/gkac591/6640223
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Inhibition of DYRK1A, via histone modification, promotes cardiomyocyte cell cycle activation and cardiac repair after myocardial infarction

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1. scibot 09 Jul 2022
  
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  DOI: 10.1016/j.ebiom.2022.104139
  
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sciencedirect.com/science/article/pii/S2352396422003206
Jun 2022
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MacroH2As regulate enhancer-promoter contacts affecting enhancer activity and sensitivity to inflammatory cytokines

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1. scibot 22 Jun 2022
  
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  DOI: 10.1016/j.celrep.2022.110988
  
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sciencedirect.com/science/article/pii/S2211124722007744
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TCF-1 promotes chromatin interactions across topologically associating domains in T cell progenitors

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1. scibot 22 Jun 2022
  
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  DOI: 10.1038/s41590-022-01232-z
  
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nature.com/articles/s41590-022-01232-z
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Dynamic Chromatin States Coupling with Key Transcription Factors in Colitis-Associated Colorectal Cancer

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1. scibot 18 Jun 2022
  
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  DOI: 10.1002/advs.202200536
  
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pmc.ncbi.nlm.nih.gov/articles/PMC9376751/
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Analysis of estrogen-regulated enhancer RNAs identifies a functional motif required for enhancer assembly and gene expression

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1. scibot 15 Jun 2022
  
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  DOI: 10.1016/j.celrep.2022.110944
  
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sciencedirect.com/science/article/pii/S2211124722007264
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Mapping cis-regulatory elements in human neurons links psychiatric disease heritability and activity-regulated transcriptional programs

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  DOI: 10.1016/j.celrep.2022.110877
  
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sciencedirect.com/science/article/pii/S2211124722006520
May 2022
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Binary outcomes of enhancer activity underlie stable random monoallelic expression

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1. scibot 28 May 2022
  
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  DOI: 10.7554/eLife.74204
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9135403/
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Large-scale chromatin reorganization reactivates placenta-specific genes that drive cellular aging

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  DOI: 10.1016/j.devcel.2022.05.004
  
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XIST loss impairs mammary stem cell differentiation and increases tumorigenicity through Mediator hyperactivation

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  DOI: 10.1016/j.cell.2022.04.034
  
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C/EBPδ-induced epigenetic changes control the dynamic gene transcription of S100a8 and S100a9

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1. scibot 24 May 2022
  
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  DOI: 10.7554/eLife.75594
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9122501/
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Transcription activation is enhanced by multivalent interactions independent of phase separation

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  DOI: 10.1016/j.molcel.2022.04.017
  
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NSD1 mediates antagonism between SWI/SNF and polycomb complexes and is required for transcriptional activation upon EZH2 inhibition

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1. scibot 12 May 2022
  
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  DOI: 10.1016/j.molcel.2022.04.015
  
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ISL2 is a putative tumor suppressor whose epigenetic silencing reprograms the metabolism of pancreatic cancer

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  DOI: 10.1016/j.devcel.2022.04.014
  
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Selective requirement of MYB for oncogenic hyperactivation of a translocated enhancer in leukemia

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1. scibot 03 May 2022
  
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  DOI: 10.1158/2159-8290.CD-20-1793
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8563373/
Apr 2022
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Functional elements of the cis-regulatory lincRNA-p21

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  DOI: 10.1016/j.celrep.2022.110687
  
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sciencedirect.com/science/article/pii/S2211124722004454
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An enriched environment reduces hippocampal inflammatory... : Neural Regeneration Research

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  DOI: 10.4103/1673-5374.338999
  
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journals.lww.com/nrronline/Fulltext/2022/11000/An_enriched_environment_reduces_hippocampal.37.aspx
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Targeted Therapy of TERT-Rearranged Neuroblastoma with BET Bromodomain Inhibitor and Proteasome Inhibitor Combination Therapy

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1. scibot 07 Apr 2022
  
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  DOI: 10.1158/1078-0432.CCR-20-3044
  
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aacrjournals.org/clincancerres/article/27/5/1438/83571/Targeted-Therapy-of-TERT-Rearranged-Neuroblastoma
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Altered BAF occupancy and transcription factor dynamics in PBAF-deficient melanoma

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  DOI: 10.1016/j.celrep.2022.110637
  
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The FUS::DDIT3 fusion oncoprotein inhibits BAF complex targeting and activity in myxoid liposarcoma

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  DOI: 10.1016/j.molcel.2022.03.019
  
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MUC1-C Dictates JUN and BAF-mediated Chromatin Remodeling at Enhancer Signatures in Cancer Stem Cells

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1. scibot 05 Apr 2022
  
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  DOI: 10.1158/1541-7786.MCR-21-0672
  
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aacrjournals.org/mcr/article/20/4/556/682310/MUC1-C-Dictates-JUN-and-BAF-Mediated-Chromatin
Mar 2022
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Mucus sialylation determines intestinal host-commensal homeostasis

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1. scibot 26 Mar 2022
  
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  DOI: 10.1016/j.cell.2022.02.013
  
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The mTOR chromatin-bound interactome in prostate cancer

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1. scibot 23 Mar 2022
  
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  DOI: 10.1016/j.celrep.2022.110534
  
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The BTB transcription factors ZBTB11 and ZFP131 maintain pluripotency by repressing pro-differentiation genes

1
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  DOI: 10.1016/j.celrep.2022.110524
  
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EP300 Selectively Controls the Enhancer Landscape of MYCN-Amplified Neuroblastoma

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STAT3-mediated allelic imbalance of novel genetic variant rs1047643 and B cell specific super-enhancer in association with systemic lupus erythematosus

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The landscape of pioneer factor activity reveals the mechanisms of chromatin reprogramming and genome activation

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Histone marks regulate the epithelial-to-mesenchymal transition via alternative splicing

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Ketogenic diet and chemotherapy combine to disrupt pancreatic cancer metabolism and growth

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Chemical-induced chromatin remodeling reprograms mouse ESCs to totipotent-like stem cells

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In vivo CRISPR screening identifies BAZ2 chromatin remodelers as druggable regulators of mammalian liver regeneration

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An oncogenic enhancer encodes selective selenium dependency in AML

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ASH1L haploinsufficiency results in autistic-like phenotypes in mice and links Eph receptor gene to autism spectrum disorder

1
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  DOI: 10.1016/j.neuron.2021.12.035
  
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Multimodal regulatory elements within a hormone-specific super enhancer control a heterogeneous transcriptional response

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SETDB1/NSD-dependent H3K9me3/H3K36me3 dual heterochromatin maintains gene expression profiles by bookmarking poised enhancers

1
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Multi-CUT&Tag to simultaneously profile multiple chromatin factors

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Single-cell-resolved dynamics of chromatin architecture delineate cell and regulatory states in zebrafish embryos

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Chromatin alterations during the epididymal maturation of mouse sperm refine the paternally inherited epigenome

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YAP1 and PRDM14 converge to promote cell survival and tumorigenesis

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SUMOylation of linker histone H1 drives chromatin condensation and restriction of embryonic cell fate identity

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Differentiation of fetal hematopoietic stem cells requires ARID4B to restrict autocrine KITLG/KIT-Src signaling

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Reprogramming of H3K9bhb at regulatory elements is a key feature of fasting in the small intestine

1
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An epigenetic mechanism underlying chromosome 17p deletion-driven tumorigenesis

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Genome-wide profiling in colorectal cancer identifies PHF19 and TBC1D16 as oncogenic super enhancers

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  DOI: 10.1038/s41467-021-26600-5
  
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1-deoxysphingolipids bind to COUP-TF to modulate lymphatic and cardiac cell development

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Global characterization of macrophage polarization mechanisms and identification of M2-type polarization inhibitors

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Impaired glucocorticoid receptor expression in liver disrupts feeding-induced gene expression, glucose uptake, and glycogen storage

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Acute depletion of the ARID1A subunit of SWI/SNF complexes reveals distinct pathways for activation and repression of transcription

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An expansion of the non-coding genome and its regulatory potential underlies vertebrate neuronal diversity

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Reprogramming CBX8-PRC1 function with a positive allosteric modulator

1
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A bipartite element with allele-specific functions safeguards DNA methylation imprints at the Dlk1-Dio3 locus

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Increased ACTL6A occupancy within mSWI/SNF chromatin remodelers drives human squamous cell carcinoma

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The Parkinson’s-disease-associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1

1
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NRF1 association with AUTS2-Polycomb mediates specific gene activation in the brain

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Simultaneous profiling of multiple chromatin proteins in the same cells

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Enhancer recruitment of transcription repressors RUNX1 and TLE3 by mis-expressed FOXC1 blocks differentiation in acute myeloid leukemia

1
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ATF3 promotes the serine synthesis pathway and tumor growth under dietary serine restriction

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Environment tunes propagation of cell-to-cell variation in the human macrophage gene network

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  DOI: 10.1016/j.cels.2017.03.002
  
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Parallel Reporter Assays Identify Altered Regulatory Role of rs684232 in Leading to Prostate Cancer Predisposition

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ASCL1, NKX2-1, and PROX1 co-regulate subtype-specific genes in small-cell lung cancer

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Rewiring of human neurodevelopmental gene regulatory programs by human accelerated regions

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Quantitative control of noise in mammalian gene expression by dynamic histone regulation

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Enhancer RNA m6A methylation facilitates transcriptional condensate formation and gene activation

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Stromal induction of BRD4 phosphorylation Results in Chromatin Remodeling and BET inhibitor Resistance in Colorectal Cancer

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Adipocyte ACLY Facilitates Dietary Carbohydrate Handling to Maintain Metabolic Homeostasis in Females

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Multi-omic Profiling Reveals Dynamics of the Phased Progression of Pluripotency

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Deterministic Somatic Cell Reprogramming Involves Continuous Transcriptional Changes Governed by Myc and Epigenetic-Driven Modules

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ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency

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Multiomics analyses reveal a critical role of selenium in controlling T cell differentiation in Crohn’s disease

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Resistance to Epigenetic-Targeted Therapy Engenders Tumor Cell Vulnerabilities Associated with Enhancer Remodeling

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KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance

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TFEB-mediated endolysosomal activity controls human hematopoietic stem cell fate

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Gestational Diabetes Epigenetically Reprograms the Cart Promoter in Fetal Ovary, Causing Subfertility in Adult Life

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The Lineage Determining Factor GRHL2 Collaborates with FOXA1 to Establish a Targetable Pathway in Endocrine Therapy-Resistant Breast Cancer

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The Transcription Factor Bhlhe40 Programs Mitochondrial Regulation of Resident CD8+ T Cell Fitness and Functionality

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SUMO Safeguards Somatic and Pluripotent Cell Identities by Enforcing Distinct Chromatin States

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Enhancer Architecture and Essential Core Regulatory Circuitry of Chronic Lymphocytic Leukemia

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A Lamina-Associated Domain Border Governs Nuclear Lamina Interactions, Transcription, and Recombination of the Tcrb Locus

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Thyroid Hormone Receptor β Suppression of RUNX2 is Mediated by Brahma Related Gene 1 Dependent Chromatin Remodeling

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  DOI: 10.1210/en.2018-00128
  
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Multi-omic Profiling Reveals Dynamics of the Phased Progression of Pluripotency

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AML Subtype Is a Major Determinant of the Association between Prognostic Gene Expression Signatures and Their Clinical Significance

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Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity

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Reprogramming of bivalent chromatin states in NRAS mutant melanoma suggests PRC2 inhibition as a therapeutic strategy

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Protocol to apply spike-in ChIP-seq to capture massive histone acetylation in human cells

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Neuronal activity-induced BRG1 phosphorylation regulates enhancer activation

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Mapping the residue specificities of epigenome enzymes by yeast surface display

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BAP1 enhances Polycomb repression by counteracting widespread H2AK119ub1 deposition and chromatin condensation

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Suv4-20h2 protects against influenza virus infection by suppression of chromatin loop formation

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DDB1 binds histone reader BRWD3 to activate the transcriptional cascade in adipogenesis and promote onset of obesity

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STAG2 loss rewires oncogenic and developmental programs to promote metastasis in Ewing sarcoma

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A PGE2-MEF2A axis enables context-dependent control of inflammatory gene expression

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  DOI: 10.1016/j.immuni.2021.05.016
  
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Muscle regeneration controlled by a designated DNA dioxygenase

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  DOI: 10.1038/s41419-021-03817-2
  
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Stk24 protects against obesity-associated metabolic disorders by disrupting the NLRP3 inflammasome

1
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  DOI: 10.1016/j.celrep.2021.109161
  
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Phase separation of OCT4 controls TAD reorganization to promote cell fate transitions

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  DOI: 10.1016/j.stem.2021.04.023
  
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Unrestrained poly-ADP-ribosylation provides insights into chromatin regulation and human disease

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  DOI: 10.1016/j.molcel.2021.04.028
  
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Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition

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A protocol for rapid degradation of endogenous transcription factors in mammalian cells and identification of direct regulatory targets

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Induction of OCT2 contributes to regulate the gene expression program in human neutrophils activated via TLR8

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Intrinsically disordered Meningioma-1 stabilizes the BAF complex to cause AML

1
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Non-canonical Targets of HIF1a Impair Oligodendrocyte Progenitor Cell Function

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Histone Acetyltransferase MOF Blocks Acquisition of Quiescence in Ground-State ESCs through Activating Fatty Acid Oxidation

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An Activity-Mediated Transition in Transcription in Early Postnatal Neurons

1
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  DOI: 10.1016/j.neuron.2020.06.008
  
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Enhancers are activated by p300/CBP activity-dependent PIC assembly, RNAPII recruitment, and pause release

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Interferon-γ induces tumor resistance to anti-PD-1 immunotherapy by promoting YAP phase separation

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Unique Immune Cell Coactivators Specify Locus Control Region Function and Cell Stage

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Robust Hi-C Maps of Enhancer-Promoter Interactions Reveal the Function of Non-coding Genome in Neural Development and Diseases

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Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer

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  DOI: 10.1016/j.molcel.2020.04.027
  
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Rapid Enhancer Remodeling and Transcription Factor Repurposing Enable High Magnitude Gene Induction upon Acute Activation of NK Cells

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  DOI: 10.1016/j.immuni.2020.09.008
  
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Genome‐Wide Estrogen Receptor β Chromatin Binding in Human Colon Cancer Cells Reveals its Tumor Suppressor Activity

1
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  RRID:AB_2118291
  
  DOI: 10.1002/ijc.33573
  
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Endogenous Retrovirus-Derived lncRNA BANCR Promotes Cardiomyocyte Migration in Humans and Non-human Primates

1
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  DOI: 10.1016/j.devcel.2020.07.006
  
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Folding Keratin Gene Clusters during Skin Regional Specification

1
1. scibot 05 May 2021
  
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  DOI: 10.1016/j.devcel.2020.05.007
  
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H3K27ac bookmarking promotes rapid post-mitotic activation of the pluripotent stem cell program without impacting 3D chromatin reorganization

1
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  DOI: 10.1016/j.molcel.2021.02.032
  
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The ZMYND8-regulated mevalonate pathway endows YAP-high intestinal cancer with metabolic vulnerability

1
1. scibot 01 May 2021
  
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  DOI: 10.1016/j.molcel.2021.04.009
  
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Apr 2021
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STAG2 mutations alter CTCF-anchored loop extrusion, reduce cis-regulatory interactions and EWSR1-FLI1 activity in Ewing sarcoma

1
1. scibot 30 Apr 2021
  
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  DOI: 10.1016/j.ccell.2021.04.001
  
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Principles of signaling pathway modulation for enhancing human naive pluripotency induction

1
1. scibot 29 Apr 2021
  
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  RRID:AB_2118291
  
  DOI: 10.1016/j.stem.2021.04.001
  
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B cell-specific XIST complex enforces X-inactivation and restrains atypical B cells

1
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  RRID:AB_2118291
  
  DOI: 10.1016/j.cell.2021.02.015
  
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Human placental cytotrophoblast epigenome dynamics over gestation and alterations in placental disease

1
1. scibot 23 Apr 2021
  
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  DOI: 10.1016/j.devcel.2021.04.001
  
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A compendium and comparative epigenomics analysis of cis -regulatory elements in the pig genome

1
1. scibot 22 Apr 2021
  
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  DOI: 10.1038/s41467-021-22448-x
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8044108/
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Isoform-specific and signaling-dependent propagation of acute myeloid leukemia by Wilms tumor 1

1
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  DOI: 10.1016/j.celrep.2021.109010
  
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IL6/STAT3 Signaling Hijacks Estrogen Receptor α Enhancers to Drive Breast Cancer Metastasis

1
1. scibot 20 Apr 2021
  
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  DOI: 10.1016/j.ccell.2020.06.007
  
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cell.com/cancer-cell/fulltext/S1535-6108(20)30311-1
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Multi-omic profiling of pituitary thyrotropic cells and progenitors

1
1. scibot 20 Apr 2021
  
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  DOI: 10.1186/s12915-021-01009-0
  
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TOP1 inhibition therapy protects against SARS-CoV-2-induced lethal inflammation

1
1. scibot 14 Apr 2021
  
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  RRID:AB_2118291
  
  DOI: 10.1016/j.cell.2021.03.051
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8008343/
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MLL3 suppresses tumorigenesis through regulating TNS3 enhancer activity

1
1. scibot 13 Apr 2021
  
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  DOI: 10.1038/s41419-021-03647-2
  
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nature.com/articles/s41419-021-03647-2
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Deficiency of histone methyltransferase SETD2 in liver leads to abnormal lipid metabolism and hepatocarcinoma

1
1. scibot 09 Apr 2021
  
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  RRID:AB_2118291
  
  DOI: 10.1002/hep.31594
  
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aasldpubs.onlinelibrary.wiley.com/doi/10.1002/hep.31594
Mar 2021
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Transcriptional programming drives Ibrutinib-resistance evolution in mantle cell lymphoma

1
1. scibot 17 Mar 2021
  
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  AB_2118291
  
  DOI: 10.1016/j.celrep.2021.108870
  
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sciencedirect.com/science/article/pii/S2211124721001844
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Astrocytic ApoE reprograms neuronal cholesterol metabolism and histone-acetylation-mediated memory

1
1. scibot 15 Mar 2021
  
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  RRID:AB_2118291
  
  DOI: 10.1016/j.neuron.2021.01.005
  
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sciencedirect.com/science/article/pii/S0896627321000052
Feb 2021
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Targeted degradation of the enhancer lysine acetyltransferases CBP and p300

1
1. scibot 28 Feb 2021
  
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  RRID:AB_2118291
  
  DOI: 10.1016/j.chembiol.2020.12.004
  
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Acetyl-CoA Synthetase 2: A Critical Linkage in Obesity-Induced Tumorigenesis in Myeloma

1
1. scibot 28 Feb 2021
  
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  RRID:AB_2118291
  
  DOI: 10.1016/j.cmet.2020.12.011
  
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The enhancer RNA lnc-SLC4A1-1 epigenetically regulates unexplained recurrent pregnancy loss (URPL) by activating CXCL8 and NF-kB pathway

1
1. scibot 26 Feb 2021
  
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  RRID:AB_2118291
  
  DOI: 10.1016/j.ebiom.2018.11.015
  
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thelancet.com/journals/ebiom/article/PIIS2352-3964(18)30508-5/fulltext
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A Genome-wide CRISPR Screen Reveals a Role for the Non-Canonical Nucleosome-Remodeling BAF Complex in Foxp3 Expression and Regulatory T Cell Function

1
1. scibot 25 Feb 2021
  
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  RRID:AB_2118291
  
  DOI: 10.1016/j.immuni.2020.06.011
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7341821/
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A unique histone 3 lysine 14 chromatin signature underlies tissue-specific gene regulation

1
1. scibot 25 Feb 2021
  
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  RRID:AB_2118291
  
  DOI: 10.1016/j.molcel.2021.01.041
  
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The corepressors GPS2 and SMRT control enhancer and silencer remodeling via eRNA transcription during inflammatory activation of macrophages

1
1. scibot 25 Feb 2021
  
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  RRID:AB_2118291
  
  DOI: 10.1016/j.molcel.2020.12.040
  
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sciencedirect.com/science/article/pii/S1097276520309618
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Definition of a small core transcriptional circuit regulated by AML1-ETO

1
1. scibot 25 Feb 2021
  
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  RRID:AB_2118291
  
  DOI: 10.1016/j.molcel.2020.12.005
  
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cell.com/molecular-cell/fulltext/S1097-2765(20)30897-2
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An acetyl-histone vulnerability in PI3K/AKT inhibition-resistant cancers is targetable by both BET and HDAC inhibitors

1
1. scibot 24 Feb 2021
  
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  RRID:AB_2118291
  
  DOI: 10.1016/j.celrep.2021.108744
  
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sciencedirect.com/science/article/pii/S2211124721000577
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The glucocorticoid receptor recruits the COMPASS complex to regulate inflammatory transcription at macrophage enhancers

1
1. scibot 11 Feb 2021
  
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  RRID:AB_2118291
  
  DOI: 10.1016/j.celrep.2021.108742
  
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sciencedirect.com/science/article/pii/S2211124721000553
Jan 2021
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Three-dimensional interactions between enhancers and promoters during intestinal differentiation depend upon HNF4

1
1. scibot 27 Jan 2021
  
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  RRID:AB_2118291
  
  DOI: 10.1016/j.celrep.2020.108679
  
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The Hox Transcription Factor Ubx Ensures Somatic Myogenesis by Suppressing the Mesodermal Master Regulator Twist

1
1. scibot 08 Jan 2021
  
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  RRID:AB_2118291
  
  DOI: 10.1016/j.celrep.2020.108577
  
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sciencedirect.com/science/article/pii/S2211124720315667
Dec 2020
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

DNMT3A Haploinsufficiency Results in Behavioral Deficits and Global Epigenomic Dysregulation Shared across Neurodevelopmental Disorders

1
1. scibot 07 Dec 2020
  
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  DOI: 10.1016/j.celrep.2020.108416
  
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pubmed.ncbi.nlm.nih.gov/33238114/
Nov 2020
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Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection

1
1. scibot 05 Nov 2020
  
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  RRID:AB_2118291
  
  DOI: 10.1016/j.cell.2020.10.028
  
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Characterization of Organoid Cultures to Study the Effects of Pregnancy Hormones on the Epigenome and Transcriptional Output of Mammary Epithelial Cells

1
1. scibot 04 Nov 2020
  
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  RRID:AB_2118291
  
  DOI: 10.1007/s10911-020-09465-0
  
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link.springer.com/article/10.1007/s10911-020-09465-0
Oct 2020
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling in KMT2D Mutant Melanoma

1
1. scibot 27 Oct 2020
  
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  AB_2118291
  
  DOI: 10.1016/j.celrep.2020.108293
  
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pubmed.ncbi.nlm.nih.gov/33086062/
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Integrated multi-omics reveal epigenomic disturbance of assisted reproductive technologies in human offspring

1
1. scibot 27 Oct 2020
  
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  RRID:AB_2118291
  
  DOI: 10.1016/j.ebiom.2020.103076
  
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sciencedirect.com/science/article/pii/S2352396420304527
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Modulating Androgen Receptor-Driven Transcription in Prostate Cancer with Selective CDK9 Inhibitors

1
1. scibot 27 Oct 2020
  
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  RRID:AB_2118291
  
  DOI: 10.1016/j.chembiol.2020.10.001
  
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Senescence Induced by BMI1 Inhibition Is a Therapeutic Vulnerability in H3K27M-Mutant DIPG

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cell.com/cell-reports/abstract/S2211-1247(20)31275-4
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The Gene-Regulatory Footprint of Aging Highlights Conserved Central Regulators

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  DOI: 10.1016/j.celrep.2020.108203
  
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Large domains of heterochromatin direct the formation of short mitotic chromosome loops

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  DOI: 10.7554/eLife.57212
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7515631/
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Anti-adipogenic signals at the onset of obesity-related inflammation in white adipose tissue

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  DOI: 10.1007/s00018-020-03485-z
  
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The Number of Transcription Factors at an Enhancer Determines Switch-like Gene Expression

1
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  DOI: 10.1016/j.celrep.2020.107724
  
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H3K4me1 Distribution Predicts Transcription State and Poising at Promoters

1
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  DOI: 10.3389/fcell.2020.00289
  
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Chromatin Remodeling and Immediate Early Gene Activation by SLFN11 in Response to Replication Stress

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1. scibot 23 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.02.117
  
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Pbrm1 Steers Mesenchymal Stromal Cell Osteolineage Differentiation by Integrating PBAF-Dependent Chromatin Remodeling and BMP/TGF-β Signaling

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  DOI: 10.1016/j.celrep.2020.107570
  
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Microbiota-Derived Metabolites Suppress Arthritis by Amplifying Aryl-Hydrocarbon Receptor Activation in Regulatory B Cells

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  DOI: 10.1016/j.cmet.2020.03.003
  
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Genome-wide Profiling Identifies DNA Methylation Signatures of Aging in Rod Photoreceptors Associated with Alterations in Energy Metabolism

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  DOI: 10.1016/j.celrep.2020.107525
  
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Super-Enhancer Redistribution as a Mechanism of Broad Gene Dysregulation in Repeatedly Drug-Treated Cancer Cells

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  DOI: 10.1016/j.celrep.2020.107532
  
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Analysis of zebrafish periderm enhancers facilitates identification of a regulatory variant near human KRT8/18

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  DOI: 10.7554/eLife.51325
  
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GLI transcriptional repression regulates tissue-specific enhancer activity in response to Hedgehog signaling

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  DOI: 10.7554/eLife.50670
  
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REST Inhibits Direct Reprogramming of Pancreatic Exocrine to Endocrine Cells by Preventing PDX1-Mediated Activation of Endocrine Genes

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  DOI: 10.1016/j.celrep.2020.107591
  
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cancerdiscovery.aacrjournals.org cancerdiscovery.aacrjournals.org

Gata3-controlled nucleosome eviction drives Myc enhancer activity in T-cell development and leukemia

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  DOI: 10.1158/2159-8290.CD-19-0471
  
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cancerdiscovery.aacrjournals.org/content/9/12/1774
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Expression of RUNX1-ETO Rapidly Alters the Chromatin Landscape and Growth of Early Human Myeloid Precursor Cells

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  DOI: 10.1016/j.celrep.2020.107691
  
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Hominoid-Specific Transposable Elements and KZFPs Facilitate Human Embryonic Genome Activation and Control Transcription in Naive Human ESCs

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  DOI: 10.1016/j.stem.2019.03.012
  
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cell.com/cell-stem-cell/abstract/S1934-5909(19)30111-0
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Large DNA Methylation Nadirs Anchor Chromatin Loops Maintaining Hematopoietic Stem Cell Identity

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  DOI: 10.1016/j.molcel.2020.04.018
  
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Genetic Variation in Type 1 Diabetes Reconfigures the 3D Chromatin Organization of T Cells and Alters Gene Expression

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  DOI: 10.1016/j.immuni.2020.01.003
  
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The testis protein ZNF165 is a SMAD3 cofactor that coordinates oncogenic TGFβ signaling in triple-negative breast cancer

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  DOI: 10.7554/eLife.57679
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7302877/

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