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619 Matching Annotations

Jun 2023
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Patterned cPCDH expression regulates the fine organization of the neocortex

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1. scibot 10 Jun 2023
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10249668/
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Genetic recording of in vivo cell proliferation by ProTracer

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  DOI: 10.1038/s41596-023-00833-8
  
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nature.com/articles/s41596-023-00833-8
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Liver and muscle circadian clocks cooperate to support glucose tolerance in mice

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1. scibot 03 Jun 2023
  
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  DOI: 10.1016/j.celrep.2023.112588
  
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sciencedirect.com/science/article/pii/S2211124723005995
May 2023
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DRD1 signaling modulates TrkB turnover and BDNF sensitivity in direct pathway striatal medium spiny neurons

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1. scibot 31 May 2023
  
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Running throughout Middle-Age Keeps Old Adult-Born Neurons Wired

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1. scibot 31 May 2023
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10217125/
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Atf3 defines a population of pulmonary endothelial cells essential for lung regeneration

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1. scibot 31 May 2023
  
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  DOI: 10.7554/eLife.83835
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10219650/
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FriendlyClearMap: an optimized toolkit for mouse brain mapping and analysis

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1. scibot 24 May 2023
  
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  DOI: 10.1093/gigascience/giad035
  
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academic.oup.com/gigascience/article/doi/10.1093/gigascience/giad035/7176210
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Allnighter pseudokinase-mediated feedback links proteostasis and sleep in Drosophila

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1. scibot 23 May 2023
  
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nature.com/articles/s41467-023-38485-7
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Prox2 and Runx3 vagal sensory neurons regulate esophageal motility

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1. scibot 17 May 2023
  
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  DOI: 10.1016/j.neuron.2023.04.025
  
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An in vivo neuroimmune organoid model to study human microglia phenotypes

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1. scibot 12 May 2023
  
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  DOI: 10.1016/j.cell.2023.04.022
  
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IGFBP2 expressing midlobular hepatocytes preferentially contribute to liver homeostasis and regeneration

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1. scibot 05 May 2023
  
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  DOI: 10.1016/j.stem.2023.04.007
  
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A junction-dependent mechanism drives murine mammary cell intercalation for ductal elongation

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1. scibot 04 May 2023
  
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Apr 2023
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Temporal and spatial staging of lung alveolar regeneration is determined by the grainyhead transcription factor Tfcp2l1

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1. scibot 29 Apr 2023
  
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PTEN deletion in spinal pathways via retrograde transduction with AAV-retro enhances forelimb motor recovery after cervical spinal cord injury; sex differences and late-onset pathophysiologies

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1. scibot 28 Apr 2023
  
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  DOI: 10.1101/2023.03.20.533502
  
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biorxiv.org/content/10.1101/2023.03.20.533502v1
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Kupffer-cell-derived IL-6 is repurposed for hepatocyte dedifferentiation via activating progenitor genes from injury-specific enhancers

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1. scibot 27 Apr 2023
  
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Generation of a MyoD knock-in reporter mouse line to study muscle stem cell dynamics and heterogeneity

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1. scibot 21 Apr 2023
  
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  DOI: 10.1016/j.isci.2023.106592
  
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Dysregulated lung stroma drives emphysema exacerbation by potentiating resident lymphocytes to suppress an epithelial stem cell reservoir

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1. scibot 20 Apr 2023
  
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  DOI: 10.1016/j.immuni.2023.01.032
  
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Pyramidal neurons form active, transient, multilayered circuits perturbed by autism-associated mutations at the inception of neocortex

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1. scibot 19 Apr 2023
  
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COMBINe enables automated detection and classification of neurons and astrocytes in tissue-cleared mouse brains

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1. scibot 19 Apr 2023
  
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  DOI: 10.1016/j.crmeth.2023.100454
  
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Notch1 signaling is limited in healthy mature kidneys in vivo

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1. scibot 18 Apr 2023
  
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  DOI: 10.1186/s13104-023-06326-x
  
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link.springer.com/article/10.1186/s13104-023-06326-x
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Heterozygous Dab1 null mutation disrupts neocortical and hippocampal development

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Stem cell competition driven by the Axin2-p53 axis controls brain size during murine development

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Positive selection of somatically mutated clones identifies adaptive pathways in metabolic liver disease

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Oxylipin-PPARγ-initiated adipocyte senescence propagates secondary senescence in the bone marrow

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1. scibot 06 Apr 2023
  
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Acute manipulation and real-time visualization of membrane trafficking and exocytosis in Drosophila

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Polarity inversion reorganizes the stem cell compartment of the trophoblast lineage

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1. scibot 30 Mar 2023
  
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Divergent projections from locus coeruleus to the corticobasal ganglia system and ventral tegmental area of the adult male zebra finch

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1. scibot 30 Mar 2023
  
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  DOI: 10.1002/cne.25474
  
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Examining the engram encoding specificity hypothesis in mice

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1. scibot 29 Mar 2023
  
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Rescue of astrocyte activity by the calcium sensor STIM1 restores long-term synaptic plasticity in female mice modelling Alzheimer’s disease

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1. scibot 26 Mar 2023
  
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Vascular and perivascular cell profiling reveals the molecular and cellular bases of blood-brain barrier heterogeneity

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1. scibot 23 Mar 2023
  
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  DOI: 10.1101/2021.04.26.441465
  
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Inter-axonal molecular crosstalk via Lumican proteoglycan sculpts murine cervical corticospinal innervation by distinct subpopulations

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A whole-brain monosynaptic input connectome to neuron classes in mouse visual cortex

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1. scibot 17 Mar 2023
  
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  DOI: 10.1038/s41593-022-01219-x
  
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FGF21 counteracts alcohol intoxication by activating the noradrenergic nervous system

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1. scibot 11 Mar 2023
  
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hPSC-derived sacral neural crest enables rescue in a severe model of Hirschsprung’s disease

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  DOI: 10.1016/j.stem.2023.02.003
  
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Developmental neuronal origin regulates neocortical map formation

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  DOI: 10.1016/j.celrep.2023.112170
  
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Parallel streams of raphe VGLUT3-positive inputs target the dorsal and ventral hippocampus in each hemisphere

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1. scibot 02 Mar 2023
  
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  DOI: 10.1002/cne.25452
  
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Tcf21 marks visceral adipose mesenchymal progenitors and functions as a rate-limiting factor during visceral adipose tissue development

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Protein composition of axonal dopamine release sites in the striatum

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Bone metastasis initiation is coupled with bone remodeling through osteogenic differentiation of NG2+ cells

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Regional and cell-type-specific afferent and efferent projections of the mouse claustrum

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GEARBOCS: An Adeno Associated Virus Tool for In Vivo Gene Editing in Astrocytes

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Graded mesoderm assembly governs cell fate and morphogenesis of the early mammalian heart

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Intermittent fasting induces rapid hepatocyte proliferation to restore the hepatostat in the mouse liver

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Spinal premotor interneurons controlling antagonistic muscles are spatially intermingled

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Highly selective transgene expression through the flip-excision switch system by using a unilateral spacer sequence

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Neuronal and astrocytic contributions to Huntington’s disease dissected with zinc finger protein transcriptional repressors

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Evolutionary assembly and disassembly of the mammalian sternum

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Jacob-induced transcriptional inactivation of CREB promotes Aβ-induced synapse loss in Alzheimer's disease

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Structural and functional map for forelimb movement phases between cortex and medulla

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Niche-mediated repair of airways is directed in an occupant-dependent manner

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Structural and functional distinctions of co-resident microglia and monocyte-derived macrophages after retinal degeneration

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Protocol to map multi-transmitter neurons in the mouse brain using intersectional strategy

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Mouse placenta fetal macrophages arise from endothelial cells outside the placenta

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Hedgehog regulation of epithelial cell state and morphogenesis in the larynx

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cd-22-0220-html.html

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Table 1 Antibodies and dyes compatible with mLSR-3D

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Astrocytes mediate long-lasting synaptic regulation of ventral tegmental area dopamine neurons

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Microglial Piezo1 senses Aβ fibril stiffness to restrict Alzheimer’s disease

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Sonic hedgehog-dependent recruitment of GABAergic interneurons into the developing visual thalamus

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CROCCP2 acts as a human-specific modifier of cilia dynamics and mTOR signaling to promote expansion of cortical progenitors

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Adult Camk2a gene reinstatement restores the learning and plasticity deficits of Camk2a knockout mice

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Somatotopy of mouse spinothalamic innervation and the localisation of a noxious stimulus requires DCC expression by Phox2a neurons

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Bacteria-derived peptidoglycan triggers a non-canonical NF-κB dependent response in Drosophila gustatory neurons

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Ventral hippocampus-lateral septum circuitry promotes foraging-related memory

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Mouse embryo model derived exclusively from embryonic stem cells undergoes neurulation and heart development

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A locus coeruleus-dorsal CA1 dopaminergic circuit modulates memory linking

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Lineage analysis of Cxcr4-expressing cells in the developing midbrain suggests that progressive competence restriction in dopaminergic progenitor cells contributes to the establishment of dopaminergic neuronal diversity

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Astrocyte calcium dysfunction causes early network hyperactivity in Alzheimer’s disease

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DNGR-1-tracing marks an ependymal cell subset with damage-responsive neural stem cell potential

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Rap1 controls epiblast morphogenesis in sync with the pluripotency states transition

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Astrocytic Piezo1-mediated mechanotransduction determines adult neurogenesis and cognitive functions

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Optical Clearing and 3D Analysis Optimized for Mouse and Human Pancreata

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Lymphatics and fibroblasts support intestinal stem cells in homeostasis and injury

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Activation, but not inhibition, of the indirect pathway disrupts choice rejection in a freely moving, multiple-choice foraging task

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Ventral hippocampus-lateral septum circuitry promotes foraging-related memory

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Intersectional mapping of multi-transmitter neurons and other cell types in the brain

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Molecular signatures and cellular diversity during mouse habenula development

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A molecular mechanism for high salt taste in Drosophila

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Metabolic lactate production coordinates vasculature development and progenitor behavior in the developing mouse neocortex

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A brainstem circuit for nausea suppression

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Deciphering the origins and fates of steroidogenic lineages in the mouse testis

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A persistent behavioral state enables sustained predation of humans by mosquitoes

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A developmental switch between electrical and neuropeptide communication in the ventromedial hypothalamus

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A novel spinal neuron connection for heat sensation

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Astrocytes Modulate Somatostatin Interneuron Signaling in the Visual Cortex

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Analyses of transplanted human retinal ganglion cell morphology and localization in murine organotypic retinal explant culture

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Robust and sensitive in situ RNA detection using Yn-situ

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Decomposing a deterministic path to mesenchymal niche formation by two intersecting morphogen gradients

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Three-dimensional volume fluorescence-imaging of vascular plasticity in adipose tissues

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Processing of information from the parafascicular nucleus of the thalamus through the basal ganglia

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Semaphorin3A/PlexinA3 association with the Scribble scaffold for cGMP increase is required for apical dendrite development

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Subcellular proteomics of dopamine neurons in the mouse brain

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A midbrain-thalamus-cortex circuit reorganizes cortical dynamics to initiate movement

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Transcriptional regulation of neural stem cell expansion in the adult hippocampus

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Hypothalamic pregnenolone mediates recognition memory in the context of metabolic disorders

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Parallel Arousal Pathways in the Lateral Hypothalamus

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Primary germinal center-resident T follicular helper cells are a physiologically distinct subset of CXCR5hiPD-1hi T follicular helper cells

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Harnessing rAAV-retro for gene manipulations in multiple pathways that are interrupted after spinal cord injury

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SURF4-induced tubular ERGIC selectively expedites ER-to-Golgi transport

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Neuronal subtype-specific growth cone and soma purification from mammalian CNS via fractionation and fluorescent sorting for subcellular analyses and spatial mapping of local transcriptomes and proteomes

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Subcellular and regional localization of mRNA translation in midbrain dopamine neurons

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The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects

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Adaptive differentiation promotes intestinal villus recovery

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Transcriptional profiling of sequentially generated septal neuron fates

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Developmental Disruption of Erbb4 in Pet1+ Neurons Impairs Serotonergic Sub-System Connectivity and Memory Formation

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Microglia sense neuronal activity via GABA in the early postnatal hippocampus

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Dihydroceramide desaturase promotes the formation of intraluminal vesicles and inhibits autophagy to increase exosome production

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A genetically defined insula-brainstem circuit selectively controls motivational vigor

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Covert capture and attenuation of a hippocampus-dependent fear memory

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Unique Neural Circuit Connectivity of Mouse Proximal, Middle and Distal Colon Defines Regional Colonic Motor Patterns

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Combined whole-organ imaging at single-cell resolution and immunohistochemical analysis of prostate cancer and its liver and brain metastases

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Optogenetic axon guidance in embryonic zebrafish

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Hippocampal gamma and sharp-wave ripple oscillations are altered in a Cntnap2 mouse model of autism spectrum disorder

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3D biomimetic platform reveals the first interactions of the embryo and the maternal blood vessels

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An active vesicle priming machinery suppresses axon regeneration upon adult CNS injury

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Identification and characterization of CYPs induced in the Drosophila antenna by exposure to a plant odorant

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Crim1 and Kelch-like 14 exert complementary dual-directional developmental control over segmentally specific corticospinal axon projection targeting

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Corticospinal neuron subpopulation-specific developmental genes prospectively indicate mature segmentally specific axon projection targeting

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Chronic chemogenetic stimulation of the anterior olfactory nucleus reduces newborn neuron survival in the adult mouse olfactory bulb

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Defining the lineage of thermogenic perivascular adipose tissue

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Astrocytic microdomains from mouse cortex gain molecular control over long-term information storage and memory retention

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Inhibition of miR-29 activity in the myeloid lineage increases response to calcitonin and trabecular bone volume in mice

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Reprogramming reactive glia into interneurons reduces chronic seizure activity in a mouse model of mesial temporal lobe epilepsy

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Adult-born proopiomelanocortin neurons derived from Rax-expressing precursors mitigate the metabolic effects of congenital hypothalamic proopiomelanocortin deficiency

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The transcription factor BCL11A defines distinct subsets of midbrain dopaminergic neurons

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Tools for efficient analysis of neurons in a 3D reference atlas of whole mouse spinal cord

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Ductal Ngn3-expressing progenitors contribute to adult β cell neogenesis in the pancreas

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Transcriptional mechanism of IRF8 and PU.1 governs microglial activation in neurodegenerative condition

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A fluorescent reporter assay of differential gene expression response to insulin in hepatocytes

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RAL GTPases Drive Intestinal Stem Cell Function and Regeneration through Internalization of WNT Signalosomes

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Extended Flight Bouts Require Disinhibition from GABAergic Mushroom Body Neurons

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The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer

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Thalamostriatal and cerebellothalamic pathways in a songbird, the Bengalese finch

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Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids

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Tracing colonic embryonic transcriptional profiles and their reactivation upon intestinal damage

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Desmoplasia and oncogene driven acinar-to-ductal metaplasia are concurrent events during acinar cell-derived pancreatic cancer initiation in young adult mice

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Optogenetic Stimulation of the Superior Colliculus Confers Retinal Neuroprotection in a Mouse Glaucoma Model

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Genetic access to neurons in the accessory optic system reveals a role for Sema6A in midbrain circuitry mediating motion perception

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Thalamostriatal and cerebellothalamic pathways in a songbird, the Bengalese finch

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The Lactate Receptor HCAR1 Modulates Neuronal Network Activity through the Activation of Gα and Gβγ Subunits

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The Innate Immune Receptors TLR2/4 Mediate Repeated Social Defeat Stress-Induced Social Avoidance through Prefrontal Microglial Activation

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Serotonergic Modulation Enables Pathway-Specific Plasticity in a Developing Sensory Circuit in Drosophila

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Multiple cell types form the VIP amacrine cell population

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A Viral Receptor Complementation Strategy to Overcome CAV-2 Tropism for Efficient Retrograde Targeting of Neurons

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Huntingtin Is Required for Normal Excitatory Synapse Development in Cortical and Striatal Circuits

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Functional diversity for body actions in the mesencephalic locomotor region

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Heterogeneity of neurons reprogrammed from spinal cord astrocytes by the proneural factors Ascl1 and Neurogenin2

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Action potential-coupled Rho GTPase signaling drives presynaptic plasticity

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The transcription factors SIX3 and VAX1 are required for suprachiasmatic nucleus circadian output and fertility in female mice

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Anterior thalamic dysfunction underlies cognitive deficits in a subset of neuropsychiatric disease models

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Danger perception and stress response through an olfactory sensor for the bacterial metabolite hydrogen sulfide

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HepaCAM controls astrocyte self-organization and coupling

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Attenuated dopamine signaling after aversive learning is restored by ketamine to rescue escape actions

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Autophagy suppresses the formation of hepatocyte-derived cancer-initiating ductular progenitor cells in the liver

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An in vivo reporter for tracking lipid droplet dynamics in transparent zebrafish

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Differential spatiotemporal development of Purkinje cell populations and cerebellum-dependent sensorimotor behaviors

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Specific and behaviorally consequential astrocyte Gq GPCR signaling attenuation in vivo with iβARK

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Leptin receptor-expressing pericytes mediate access of hypothalamic feeding centers to circulating leptin

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Lgr6 marks epidermal stem cells with a nerve-dependent role in wound re-epithelialization

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Cholinergic neurons constitutively engage the ISR for dopamine modulation and skill learning in mice

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RHEB/mTOR hyperactivity causes cortical malformations and epileptic seizures through increased axonal connectivity

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Fibroblast dedifferentiation as a determinant of successful regeneration

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Cell of Origin Influences Pancreatic Cancer Subtype

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A suite of new Dre recombinase drivers markedly expands the ability to perform intersectional genetic targeting

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Derivation of Airway Basal Stem Cells from Human Pluripotent Stem Cells

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Decoding neuronal composition and ontogeny of individual hypothalamic nuclei

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Area Postrema Cell Types that Mediate Nausea-Associated Behaviors

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Remotely Produced and Axon-Derived Netrin-1 Instructs GABAergic Neuron Migration and Dopaminergic Substantia Nigra Development

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Neural Stem Cells Direct Axon Guidance via Their Radial Fiber Scaffold

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Stromal SOX2 Upregulation Promotes Tumorigenesis through the Generation of a SFRP1/2-Expressing Cancer-Associated Fibroblast Population

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Long-Range Optogenetic Control of Axon Guidance Overcomes Developmental Boundaries and Defects

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Prefrontal Cortical Projection Neurons Targeting Dorsomedial Striatum Control Behavioral Inhibition

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Tendon Cell Regeneration Is Mediated by Attachment Site-Resident Progenitors and BMP Signaling

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Formation of polarized contractile interfaces by self-organized Toll-8/Cirl GPCR asymmetry

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