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  1. Sep 2024
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    Starvation-induced phosphorylation activates gasdermin A to initiate pyroptosis
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  4. Aug 2024
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    TRIM24 upregulates ORM2 to alleviate abnormal lipid metabolism, inflammation, and oxidative stress in mice with obstructive sleep apnea syndrome & metabolic dysfunction-associated steatotic liver disease
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    A primate-specific endogenous retroviral envelope protein sequesters SFRP2 to regulate human cardiomyocyte development
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    Increased viral tolerance mediates by antiviral RNA interference in bat cells
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    Characterization and comparison of human glioblastoma models
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    Eugenol attenuates inflammatory response and enhances barrier function during lipopolysaccharide (LPS)-induced inflammation in the porcine intestinal epithelial (IPEC-J2) cells
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    Association of N‐cadherin levels and downstream effectors of Rho GTPases with dendritic spine loss induced by chronic stress in rat hippocampal neurons
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  11. Jul 2024
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    Specific targeting of cancer vaccines to antigen-presenting cells via an endogenous TLR2/6 ligand derived from cysteinyl-tRNA synthetase 1
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    Selective targeting of mu opioid receptors to primary cilia
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    Hyperbaric oxygen therapy increases the effect of 5-fluorouracil chemotherapy on experimental colorectal cancer in mice
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    CK2 phosphorylation of CMTR1 promotes RNA cap formation and influenza virus infection
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    The PP2A regulatory subunit PPP2R2A controls NAD+ biosynthesis to regulate T cell subset differentiation in systemic autoimmunity
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    The TSC22D, WNK, and NRBP gene families exhibit functional buffering and evolved with Metazoa for cell volume regulation
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    TSPAN4 influences glioblastoma progression through regulating EGFR stability
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    Molecular circadian clock disruption in the leukocytes of individuals with type 2 diabetes and overweight, and its relationship with leukocyte–endothelial interactions
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    GRP75-dependent mitochondria-ER contacts ensure cell survival during early mouse thymocyte development
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    Ube3a unsilencer for the potential treatment of Angelman syndrome
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  24. Jun 2024
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    eIF4F complex dynamics are important for the activation of the integrated stress response
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    De novo TLK1 and MDM1 mutations in a patient with a neurodevelopmental disorder and immunodeficiency
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    Setdb1 protects genome integrity in murine muscle stem cells to allow for regenerative myogenesis and inflammation
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    Myocardial infarction accelerates the progression of MASH by triggering immunoinflammatory response and induction of periosti
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  29. May 2024
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    NRAS mutant dictates AHCYL1-governed ER calcium homeostasis for melanoma tumor growth
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    Ataxia-Telangiectasia Mutated Loss-of-Function Displays Variant and Tissue-Specific Differences across Tumor Types
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    Modeling blood-brain barrier formation and cerebral cavernous malformations in human PSC-derived organoids
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    Patients and mice with deficiency in the SNARE protein SYNTAXIN-11 have a secondary B cell defect
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    Synergistic hyperactivation of both mTORC1 and mTORC2 underlies the neural abnormalities of PTEN-deficient human neurons and cortical organoids
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    Electronic cigarette exposure disrupts airway epithelial barrier function and exacerbates viral infection | American Journal of Physiology-Lung Cellular and Molecular Physiology
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    Genome-scale chromatin binding dynamics of RNA Polymerase II general transcription machinery components
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    The anti-leprosy drug clofazimine reduces polyQ toxicity through activation of PPARγ
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    The role of age-associated alpha-synuclein aggregation in a conditional transgenic mouse model of Parkinson's disease: Implications for Lewy body formation
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  39. Apr 2024
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    Positive selection CRISPR screens reveal a druggable pocket in an oligosaccharyltransferase required for inflammatory signaling to NF-κB
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    WW domains form a folded type of nuclear localization signal to guide YAP1 nuclear import
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    Small extracellular vesicles from hypoxia-preconditioned bone marrow mesenchymal stem cells attenuate spinal cord injury via miR-146a-5p-mediated regulation of macrophage polarization
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    Prophylactic treatment with the c-Abl inhibitor, neurotinib, diminishes neuronal damage and the convulsive state in pilocarpine-induced mice
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    Pan-neuronal expression of human mutant SOD1 in Drosophila impairs survival and motor performance, induces early neuroinflammation and chromosome aberrations
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    Suppression of Cofilin function in the somatosensory cortex alters social contact behavior in the BTBR mouse inbred line
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    Rab7-dependent regulation of goblet cell protein CLCA1 modulates gastrointestinal homeostasis
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    Repulsive Sema3E-Plexin-D1 signaling coordinates both axonal extension and steering via activating an autoregulatory factor, Mtss1
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    Systematic HOIP interactome profiling reveals critical roles of linear ubiquitination in tissue homeostasis
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    Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy
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    Small RNAs direct attack and defense mechanisms in a quorum sensing phage and its host
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    “Heterogeneous subpopulations of GABAAR-responding neurons coexist across neuronal networks scales and developmental stages in health and disease”
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  52. Mar 2024
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    RPGR is a guanine nucleotide exchange factor for the small GTPase RAB37 required for retinal function via autophagy regulation
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    The circular RNA circATP8B(2) regulates ROS production and antiviral immunity in Drosophila
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    The acetylase activity of Cdu1 regulates bacterial exit from infected cells by protecting Chlamydia effectors from degradation
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    Spatial resolution of HIV-1 post-entry steps in resting CD4 T cells
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    MOF-mediated acetylation of UHRF1 enhances UHRF1 E3 ligase activity to facilitate DNA methylation maintenance
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  58. Feb 2024
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    CircUSP1 as a novel marker promotes gastric cancer progression via stabilizing HuR to upregulate USP1 and Vimentin
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    Tonic NMDAR currents of NR2A-containing NMDARs represent altered ambient glutamate concentration in the supraoptic nucleus
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    Machine learning-based prediction models to guide the selection of Cas9 variants for efficient gene editing
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    Structural and functional insight into the interaction of Clostridioides difficile toxin B and FZD7
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    Cooperation between PRMT1 and PRMT6 drives lung cancer health disparities among Black/African American men
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  64. Jan 2024
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    PARP5A and RNF146 phase separation restrains RIPK1-dependent necroptosis
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    The mitochondrial genome-encoded peptide MOTS-c interacts with Bcl-2 to alleviate nonalcoholic steatohepatitis progression
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    Protein 4.1N plays a cell-type specific role in hippocampal glutamatergic synapse regulation
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    Tonic Activation of NR2D-Containing NMDARs Exacerbates Dopaminergic Neuronal Loss in MPTP-Injected Parkinsonian Mice
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  69. Dec 2023
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    A forebrain-hypothalamic ER stress driven circuit mediates hepatic steatosis during obesity
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    Genome-wide study reveals novel roles for formin-2 in axon regeneration as a microtubule dynamics regulator and therapeutic target for nerve repair
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    Purkinje-cell-specific MeCP2 deficiency leads to motor deficits and autistic-like behavior due to aberrations in PTP1B-TrkB-SK signaling
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    Ovarian ERβ cistrome and transcriptome reveal chromatin interaction with LRH-1
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    Autophagy is involved in degradation of AQP1 in response to an acute decrement in tonicity
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    MiR-138-5p Upregulation during Neuronal Maturation Parallels with an Increase in Neuronal Survival
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  76. Nov 2023
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    BACH1 regulates the differentiation of vascular smooth muscle cells from human embryonic stem cells via CARM1-mediated methylation of H3R17
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    Trans-vaccenic acid reprograms CD8+ T cells and anti-tumour immunity
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    SARS-CoV-2 ORF6 protein targets TRIM25 for proteasomal degradation to diminish K63-linked RIG-I ubiquitination and type-I interferon induction
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    link.springer.com/article/10.1007/s00018-023-05011-3
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    Mass isolation of staged Drosophila pupal intestines for analysis of protein ubiquitylation
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    Integrative genomic analyses identify lncRNA regulatory networks across pediatric leukemias and solid tumors
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    aacrjournals.org/cancerres/article/83/20/3462/729497/Integrative-Genomic-Analyses-Identify-LncRNA
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    Hippocampus Insulin Receptors Regulate Episodic and Spatial Memory Through Excitatory/Inhibitory Balance
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    ncbi.nlm.nih.gov/pmc/articles/PMC10621302/
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    Anaplastic thyroid cancer cells reduce CD71 levels to increase iron overload tolerance
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    Sequencing-based functional assays for classification of BRCA2 variants in mouse ESCs
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    LPGAT1 controls MEGDEL syndrome by coupling phosphatidylglycerol remodeling with mitochondrial transport
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    CD300f immune receptor contributes to healthy aging by regulating inflammaging, metabolism, and cognitive decline
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  87. Oct 2023
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    Short C-terminal Musashi-1 proteins regulate pluripotency states in embryonic stem cells
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    An early glycolysis burst in microglia regulates mitochondrial dysfunction in oligodendrocytes under neuroinflammation
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    Essential role of Mg2+ in mouse preimplantation embryo development revealed by TRPM7 chanzyme-deficient gametes
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    Intrinsically disordered region-mediated condensation of IFN-inducible SCOTIN/SHISA-5 inhibits ER-to-Golgi vesicle transport
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    MYC is a regulator of androgen receptor inhibition-induced metabolic requirements in prostate cancer
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    SARS-CoV-2 hampers dopamine production in iPSC-derived dopaminergic neurons
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  95. Sep 2023
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    Lysosomal cyst(e)ine storage potentiates tolerance to oxidative stress in cancer cells
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