671 Matching Annotations
  1. Dec 2024
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    Persistence of spike protein at the skull-meninges-brain axis may contribute to the neurological sequelae of COVID-19
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    sciencedirect.com/science/article/pii/S1931312824004384
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    A yeast-based oral therapeutic delivers immune checkpoint inhibitors to reduce intestinal tumor burden
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    sciencedirect.com/science/article/pii/S2451945624004525
  4. Nov 2024
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The role of polo‐like kinases 2 in the proteasomal and lysosomal degradation of alpha‐synuclein in neurons
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    pmc.ncbi.nlm.nih.gov/articles/PMC11580719/
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibition of cathepsin L ameliorates inflammation through the A20/NF-κB pathway in endotoxin-induced acute lung injury
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    pmc.ncbi.nlm.nih.gov/articles/PMC11570319/
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    Effects of hyperhomocysteinemia on follicular development and oocytes quality
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    pmc.ncbi.nlm.nih.gov/articles/PMC11574796/
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    Opposing roles for AMPK in regulating distinct mitophagy pathways
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    sciencedirect.com/science/article/pii/S1097276524008657
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    A p38 MAPK-ROS axis fuels proliferation stress and DNA damage during CRISPR-Cas9 gene editing in hematopoietic stem and progenitor cells
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    sciencedirect.com/science/article/pii/S2666379124005949
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    TRPM2 and CaMKII Signaling Drives Excessive GABAergic Synaptic Inhibition Following Ischemia
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    pmc.ncbi.nlm.nih.gov/articles/PMC11079974/
  11. Oct 2024
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    Hormone-mediated disassembly and inactivation of a plant E3 ubiquitin ligase complex
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    sciencedirect.com/science/article/pii/S2211124724011537
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    Antagonistic nanobodies implicate mechanism of GSDMD pore formation and potential therapeutic application
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    ncbi.nlm.nih.gov/pmc/articles/PMC11427689/
  14. Sep 2024
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    BRAF-induced EHF Expression Affects TERT in Aggressive Papillary Thyroid Cancer
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    academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgae589/7740915
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    Cecal necroptosis triggers lethal cardiac dysfunction in TNF-induced severe SIRS
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    Tanomastat exerts multi-targeted inhibitory effects on viral capsid dissociation and RNA replication in human enteroviruses
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    ncbi.nlm.nih.gov/pmc/articles/PMC11419895/
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    Highlights from MBoC Selection: Differential reliance of CTD-nuclear envelope phosphatase 1 on its regulatory subunit in ER lipid synthesis and storage
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    ncbi.nlm.nih.gov/pmc/articles/PMC11244170/
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    A PACAP-activated network for secretion requires coordination of Ca2+ influx and Ca2+ mobilization
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    ncbi.nlm.nih.gov/pmc/articles/PMC11244167/
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    Anopheles gambiae lacking AgTRIO probe inefficiently on a mammalian host
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    ncbi.nlm.nih.gov/pmc/articles/PMC11407849/
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    Activation of the NLRP1B inflammasome by caspase-8
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    nature.com/articles/s42003-024-06882-3
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    A TBK1-independent primordial function of STING in lysosomal biogenesis
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    C2H2-zinc-finger transcription factors bind RNA and function in diverse post-transcriptional regulatory processes
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    sciencedirect.com/science/article/pii/S1097276524007330
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    Cancer cell – fibroblast crosstalk via HB-EGF/EGFR/MEK signaling promotes expression of macrophage chemo-attractants in squamous cell carcinoma
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    Key roles of C2/GAP domains in SYNGAP1-related pathophysiology
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    Treatment with a combination of myricitrin and exercise alleviates myocardial infarction in rats via suppressing Nrf2/HO-1 antioxidant pathway
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    Starvation-induced phosphorylation activates gasdermin A to initiate pyroptosis
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    Antibodies and complement are key drivers of thrombosis
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  29. Aug 2024
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chronic Lithium Treatment Alters NMDA and AMPA Receptor Synaptic Availability and Dendritic Spine Organization in the Rat Hippocampus
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    ncbi.nlm.nih.gov/pmc/articles/PMC11333793/
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    A primate-specific endogenous retroviral envelope protein sequesters SFRP2 to regulate human cardiomyocyte development
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    Increased viral tolerance mediates by antiviral RNA interference in bat cells
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    Differential effect of asparagine and glutamine removal on three adenocarcinoma cell lines
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    1,10-phenanthroline inhibits sumoylation and reveals that yeast SUMO modifications are highly transient
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    Characterization and comparison of human glioblastoma models
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    Repurposing of the Antiepileptic Drug Levetiracetam to Restrain Neuroendocrine Prostate Cancer and Inhibit Mast Cell Support to Adenocarcinoma
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    frontiersin.org/articles/10.3389/fimmu.2021.622001/full
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    Association of N‐cadherin levels and downstream effectors of Rho GTPases with dendritic spine loss induced by chronic stress in rat hippocampal neurons
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    onlinelibrary.wiley.com/doi/10.1002/jnr.23602/full
  38. Jul 2024
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    Both enantiomers of β-aminoisobutyric acid BAIBA regulate Fgf23 via MRGPRD receptor by activating distinct signaling pathways in osteocytes
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    TDP1 phosphorylation by CDK1 in mitosis promotes MUS81-dependent repair of trapped Top1-DNA covalent complexes
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    FEBS Press
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  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Selective targeting of mu opioid receptors to primary cilia
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    CK2 phosphorylation of CMTR1 promotes RNA cap formation and influenza virus infection
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    Disruption of TGF-β signaling pathway is required to mediate effective killing of hepatocellular carcinoma by human iPSC-derived NK cells
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    The PP2A regulatory subunit PPP2R2A controls NAD+ biosynthesis to regulate T cell subset differentiation in systemic autoimmunity
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    The TSC22D, WNK, and NRBP gene families exhibit functional buffering and evolved with Metazoa for cell volume regulation
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    TSPAN4 influences glioblastoma progression through regulating EGFR stability
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    Regulation of Expression of Autophagy Genes by Atg8a-Interacting Partners Sequoia, YL-1, and Sir2 in Drosophila
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    ncbi.nlm.nih.gov/pmc/articles/PMC7262597/
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    A highly selective inhibitor of discoidin domain receptor-1 (DDR1-IN-1) protects corneal epithelial cells from YAP/ACSL4-mediated ferroptosis in dry eye
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16491
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    GRP75-dependent mitochondria-ER contacts ensure cell survival during early mouse thymocyte development
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    cell.com/developmental-cell/abstract/S1534-5807(24)00385-X
  54. www.nature.com www.nature.com
    Ube3a unsilencer for the potential treatment of Angelman syndrome
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    nature.com/articles/s41467-024-49788-8
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    A methodology to globally assess ectodomain shedding using soluble fractions from the mouse brain
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    ncbi.nlm.nih.gov/pmc/articles/PMC11219901/
  56. Jun 2024
  57. www.sciencedirect.com www.sciencedirect.com
    The role of JMJD2A in immune evasion and malignant behavior of esophageal squamous cell carcinoma
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    sciencedirect.com/science/article/pii/S1567576924009214
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    Setdb1 protects genome integrity in murine muscle stem cells to allow for regenerative myogenesis and inflammation
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    Myocardial infarction accelerates the progression of MASH by triggering immunoinflammatory response and induction of periosti
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    sciencedirect.com/science/article/pii/S1550413124001761
  60. May 2024
  61. aacrjournals.org aacrjournals.org
    NRAS mutant dictates AHCYL1-governed ER calcium homeostasis for melanoma tumor growth
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    aacrjournals.org/mcr/article/22/4/386/741848/NRAS-Mutant-Dictates-AHCYL1-Governed-ER-Calcium
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    SENP1 facilitates OM-MSC differentiation through activating OPTN-mediated mitophagy to mitigate the neurologic impairment following ICH
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  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ataxia-Telangiectasia Mutated Loss-of-Function Displays Variant and Tissue-Specific Differences across Tumor Types
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    Expression of the membrane tetraspanin claudin 18 on cancer cells promotes T lymphocyte infiltration and antitumor immunity in pancreatic cancer
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    CD37 is a safe chimeric antigen receptor target to treat acute myeloid leukemia
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    Synergistic hyperactivation of both mTORC1 and mTORC2 underlies the neural abnormalities of PTEN-deficient human neurons and cortical organoids
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    Electronic cigarette exposure disrupts airway epithelial barrier function and exacerbates viral infection | American Journal of Physiology-Lung Cellular and Molecular Physiology
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    4-Hydroxybenzoic acid rescues multisystemic disease and perinatal lethality in a mouse model of mitochondrial disease
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    Genome-scale chromatin binding dynamics of RNA Polymerase II general transcription machinery components
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    The anti-leprosy drug clofazimine reduces polyQ toxicity through activation of PPARγ
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    The role of age-associated alpha-synuclein aggregation in a conditional transgenic mouse model of Parkinson's disease: Implications for Lewy body formation
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    onlinelibrary.wiley.com/doi/10.1111/jnc.16122
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    A PACAP-activated network for secretion requires coordination of Ca2+ influx and Ca2+ mobilization
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    biorxiv.org/content/10.1101/2024.01.03.574069v1
  73. Apr 2024
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KIS counteracts PTBP2 and regulates alternative exon usage in neurons
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    ncbi.nlm.nih.gov/pmc/articles/PMC11045219/
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    Positive selection CRISPR screens reveal a druggable pocket in an oligosaccharyltransferase required for inflammatory signaling to NF-κB
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    WW domains form a folded type of nuclear localization signal to guide YAP1 nuclear import
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    Prophylactic treatment with the c-Abl inhibitor, neurotinib, diminishes neuronal damage and the convulsive state in pilocarpine-induced mice
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    Pan-neuronal expression of human mutant SOD1 in Drosophila impairs survival and motor performance, induces early neuroinflammation and chromosome aberrations
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    The regulation of enteric neuron connectivity by Semaphorin 5A is affected by the autism-associated S956G missense mutation
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    Functionally diverse thymic medullary epithelial cells interplay to direct central tolerance
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    Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy
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    Iterative oxidation by TET1 is required for reprogramming of imprinting control regions and patterning of mouse sperm hypomethylated regions
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  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SGMS1 Facilitates Osteogenic Differentiation of MSCs and Strengthens Osteogenesis–Angiogenesis Coupling by Modulating Cer/PP2A/Akt Pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC10966191/
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    “Heterogeneous subpopulations of GABAAR-responding neurons coexist across neuronal networks scales and developmental stages in health and disease”
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    Defects of renal tubular homeostasis and cystogenesis in the Pkhd1-knockout
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    Ribociclib leverages phosphodiesterase 4 inhibition in the treatment of neutrophilic inflammation and acute respiratory distress syndrome
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    BAI1 localizes AMPA receptors at the cochlear afferent post-synaptic density and is essential for hearing
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  88. Mar 2024
  89. www.sciencedirect.com www.sciencedirect.com
    Molecular determinants and signaling effects of PKA RIα phase separation
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    RPGR is a guanine nucleotide exchange factor for the small GTPase RAB37 required for retinal function via autophagy regulation
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    The circular RNA circATP8B(2) regulates ROS production and antiviral immunity in Drosophila
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    The acetylase activity of Cdu1 regulates bacterial exit from infected cells by protecting Chlamydia effectors from degradation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10942603/
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    INHBA is enriched in HPV-negative oropharyngeal squamous cell carcinoma and promotes cancer progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10901070/
  94. Feb 2024
  95. link.springer.com link.springer.com
    CircUSP1 as a novel marker promotes gastric cancer progression via stabilizing HuR to upregulate USP1 and Vimentin
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  191. Mar 2023
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    Mitoguardin2 is Associated with Hyperandrogenism and Regulates Steroidogenesis in Human Ovarian Granulosa Cells
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  193. www.embopress.org www.embopress.org
    Inhibition of ATM kinase rescues planarian regeneration after lethal radiation
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  194. www.mdpi.com www.mdpi.com
    NAADP-Evoked Ca2+ Signaling Leads to Mutant Huntingtin Aggregation and Autophagy Impairment in Murine Astrocytes
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    mdpi.com/1422-0067/24/6/5593
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    Prolonged Alprazolam Treatment Alters Components of Glutamatergic Neurotransmission in the Hippocampus of Male Wistar Rats&mdash;The Neuroadaptive Changes following Long-Term Benzodiazepine (Mis)Use
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  196. www.sciencedirect.com www.sciencedirect.com
    Targeting Mutant Dicer Tumorigenesis in Pleuropulmonary Blastoma via Inhibition of RNA Polymerase I
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    S-acylation stabilizes ligand-induced receptor kinase complex formation during plant pattern-triggered immune signaling
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  198. 52.53.155.43 52.53.155.43
    Inhibiting tau protein improves the recovery of spinal cord ... : Neural Regeneration Research
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    Smad4-mediated angiogenesis facilitates the beiging of white adipose tissue in mice
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  200. www.sciencedirect.com www.sciencedirect.com
    Therapeutic potency of compound RMY-205 for pulmonary fibrosis induced by SARS-CoV-2 nucleocapsid protein
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  201. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel Green Fluorescent Polyamines to Analyze ATP13A2 and ATP13A3 Activity in the Mammalian Polyamine Transport System
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    PPT1 Regulation Of HSP90α Depalmitoylation Participates In The Pathogenesis Of Hyperandrogenism
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  203. Feb 2023
  204. academic.oup.com academic.oup.com
    Non-coding mutations in a thyroid hormone receptor gene that impair cone photoreceptor function
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    academic.oup.com/endo/article/164/3/bqad006/6984996
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    Adipocyte-Secreted IL-6 Sensitizes Macrophages to IL-4 Signaling
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    The mechanosensitive ion channel Piezo1 modulates the migration and immune response of microglia
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  207. link.springer.com link.springer.com
    Cold exposure alters lipid metabolism of skeletal muscle through HIF-1α-induced mitophagy
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    The injury-induced transcription factor SOX9 alters the expression of LBR, HMGA2, and HIPK3 in human kidney
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