642 Matching Annotations
  1. Aug 2024
  2. bmccancer.biomedcentral.com bmccancer.biomedcentral.com
    Characterization and comparison of human glioblastoma models
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    bmccancer.biomedcentral.com/articles/10.1186/s12885-022-09910-9
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    Repurposing of the Antiepileptic Drug Levetiracetam to Restrain Neuroendocrine Prostate Cancer and Inhibit Mast Cell Support to Adenocarcinoma
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    frontiersin.org/articles/10.3389/fimmu.2021.622001/full
  4. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Association of N‐cadherin levels and downstream effectors of Rho GTPases with dendritic spine loss induced by chronic stress in rat hippocampal neurons
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    onlinelibrary.wiley.com/doi/10.1002/jnr.23602/full
  5. Jul 2024
  6. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004224018315-main-html.html
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    Both enantiomers of β-aminoisobutyric acid BAIBA regulate Fgf23 via MRGPRD receptor by activating distinct signaling pathways in osteocytes
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    sciencedirect.com/science/article/pii/S2211124724007253
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    paul-chowdhuri-das-2024-tdp1-phosphorylation-by-cdk1-in-mitosis-promotes-mus81-dependent-repair-of-trapped-top1-dna-html.html
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    TDP1 phosphorylation by CDK1 in mitosis promotes MUS81-dependent repair of trapped Top1-DNA covalent complexes
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    embopress.org/doi/10.1038/s44318-024-00169-3
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    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1873-3468.14978
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Selective targeting of mu opioid receptors to primary cilia
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    ncbi.nlm.nih.gov/pmc/articles/PMC11257377/
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    CK2 phosphorylation of CMTR1 promotes RNA cap formation and influenza virus infection
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    cell.com/cell-reports/abstract/S2211-1247(24)00734-4
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    Disruption of TGF-β signaling pathway is required to mediate effective killing of hepatocellular carcinoma by human iPSC-derived NK cells
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    cell.com/cell-stem-cell/abstract/S1934-5909(24)00217-0
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    The PP2A regulatory subunit PPP2R2A controls NAD+ biosynthesis to regulate T cell subset differentiation in systemic autoimmunity
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    cell.com/cell-reports/fulltext/S2211-1247(24)00707-1
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    The TSC22D, WNK, and NRBP gene families exhibit functional buffering and evolved with Metazoa for cell volume regulation
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    sciencedirect.com/science/article/pii/S2211124724007460
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    TSPAN4 influences glioblastoma progression through regulating EGFR stability
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    cell.com/iscience/fulltext/S2589-0042(24)01642-0
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  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of Expression of Autophagy Genes by Atg8a-Interacting Partners Sequoia, YL-1, and Sir2 in Drosophila
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    ncbi.nlm.nih.gov/pmc/articles/PMC7262597/
  19. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A highly selective inhibitor of discoidin domain receptor-1 (DDR1-IN-1) protects corneal epithelial cells from YAP/ACSL4-mediated ferroptosis in dry eye
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16491
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    GRP75-dependent mitochondria-ER contacts ensure cell survival during early mouse thymocyte development
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    cell.com/developmental-cell/abstract/S1534-5807(24)00385-X
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    Ube3a unsilencer for the potential treatment of Angelman syndrome
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    nature.com/articles/s41467-024-49788-8
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A methodology to globally assess ectodomain shedding using soluble fractions from the mouse brain
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    ncbi.nlm.nih.gov/pmc/articles/PMC11219901/
  23. Jun 2024
  24. www.sciencedirect.com www.sciencedirect.com
    The role of JMJD2A in immune evasion and malignant behavior of esophageal squamous cell carcinoma
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    sciencedirect.com/science/article/pii/S1567576924009214
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    Setdb1 protects genome integrity in murine muscle stem cells to allow for regenerative myogenesis and inflammation
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    sciencedirect.com/science/article/pii/S1534580724003290
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    Myocardial infarction accelerates the progression of MASH by triggering immunoinflammatory response and induction of periosti
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    sciencedirect.com/science/article/pii/S1550413124001761
  27. May 2024
  28. aacrjournals.org aacrjournals.org
    NRAS mutant dictates AHCYL1-governed ER calcium homeostasis for melanoma tumor growth
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    aacrjournals.org/mcr/article/22/4/386/741848/NRAS-Mutant-Dictates-AHCYL1-Governed-ER-Calcium
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SENP1 facilitates OM-MSC differentiation through activating OPTN-mediated mitophagy to mitigate the neurologic impairment following ICH
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    ncbi.nlm.nih.gov/pmc/articles/PMC11103578/
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ataxia-Telangiectasia Mutated Loss-of-Function Displays Variant and Tissue-Specific Differences across Tumor Types
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    ncbi.nlm.nih.gov/pmc/articles/PMC11094420/
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    Expression of the membrane tetraspanin claudin 18 on cancer cells promotes T lymphocyte infiltration and antitumor immunity in pancreatic cancer
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    sciencedirect.com/science/article/pii/S1074761324002267
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    CD37 is a safe chimeric antigen receptor target to treat acute myeloid leukemia
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    sciencedirect.com/science/article/pii/S2666379124002647
  33. 52.53.155.43 52.53.155.43
    Synergistic hyperactivation of both mTORC1 and mTORC2 underlies the neural abnormalities of PTEN-deficient human neurons and cortical organoids
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    Electronic cigarette exposure disrupts airway epithelial barrier function and exacerbates viral infection | American Journal of Physiology-Lung Cellular and Molecular Physiology
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    ncbi.nlm.nih.gov/pmc/articles/PMC11068398/
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    4-Hydroxybenzoic acid rescues multisystemic disease and perinatal lethality in a mouse model of mitochondrial disease
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    sciencedirect.com/science/article/pii/S2211124724004765
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-scale chromatin binding dynamics of RNA Polymerase II general transcription machinery components
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    ncbi.nlm.nih.gov/pmc/articles/PMC11066129/
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    The anti-leprosy drug clofazimine reduces polyQ toxicity through activation of PPARγ
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    sciencedirect.com/science/article/pii/S2352396424001592
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    The role of age-associated alpha-synuclein aggregation in a conditional transgenic mouse model of Parkinson's disease: Implications for Lewy body formation
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    onlinelibrary.wiley.com/doi/10.1111/jnc.16122
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    A PACAP-activated network for secretion requires coordination of Ca2+ influx and Ca2+ mobilization
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    biorxiv.org/content/10.1101/2024.01.03.574069v1
  40. Apr 2024
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KIS counteracts PTBP2 and regulates alternative exon usage in neurons
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    ncbi.nlm.nih.gov/pmc/articles/PMC11045219/
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    Positive selection CRISPR screens reveal a druggable pocket in an oligosaccharyltransferase required for inflammatory signaling to NF-κB
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    sciencedirect.com/science/article/pii/S0092867424003131
  43. rupress.org rupress.org
    WW domains form a folded type of nuclear localization signal to guide YAP1 nuclear import
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    rupress.org/jcb/article/223/6/e202308013/276631/WW-domains-form-a-folded-type-of-nuclear
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    Prophylactic treatment with the c-Abl inhibitor, neurotinib, diminishes neuronal damage and the convulsive state in pilocarpine-induced mice
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    Pan-neuronal expression of human mutant SOD1 in Drosophila impairs survival and motor performance, induces early neuroinflammation and chromosome aberrations
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    sciencedirect.com/science/article/pii/S0925443924001819
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    The regulation of enteric neuron connectivity by Semaphorin 5A is affected by the autism-associated S956G missense mutation
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    Functionally diverse thymic medullary epithelial cells interplay to direct central tolerance
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    sciencedirect.com/science/article/pii/S2211124724004005
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    Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy
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    nature.com/articles/s41419-024-06534-8
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    Iterative oxidation by TET1 is required for reprogramming of imprinting control regions and patterning of mouse sperm hypomethylated regions
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    sciencedirect.com/science/article/pii/S1534580724001448
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SGMS1 Facilitates Osteogenic Differentiation of MSCs and Strengthens Osteogenesis–Angiogenesis Coupling by Modulating Cer/PP2A/Akt Pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC10966191/
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    “Heterogeneous subpopulations of GABAAR-responding neurons coexist across neuronal networks scales and developmental stages in health and disease”
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    ncbi.nlm.nih.gov/pmc/articles/PMC10966311/
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    Defects of renal tubular homeostasis and cystogenesis in the Pkhd1-knockout
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    ncbi.nlm.nih.gov/pmc/articles/PMC10973142/
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    Ribociclib leverages phosphodiesterase 4 inhibition in the treatment of neutrophilic inflammation and acute respiratory distress syndrome
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    sciencedirect.com/science/article/pii/S209012322400119X
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    BAI1 localizes AMPA receptors at the cochlear afferent post-synaptic density and is essential for hearing
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    sciencedirect.com/science/article/pii/S221112472400353X
  55. Mar 2024
  56. www.sciencedirect.com www.sciencedirect.com
    Molecular determinants and signaling effects of PKA RIα phase separation
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    sciencedirect.com/science/article/pii/S1097276524001849
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    RPGR is a guanine nucleotide exchange factor for the small GTPase RAB37 required for retinal function via autophagy regulation
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    sciencedirect.com/science/article/pii/S2211124724003383
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    The circular RNA circATP8B(2) regulates ROS production and antiviral immunity in Drosophila
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    sciencedirect.com/science/article/pii/S2211124724003012
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The acetylase activity of Cdu1 regulates bacterial exit from infected cells by protecting Chlamydia effectors from degradation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10942603/
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    INHBA is enriched in HPV-negative oropharyngeal squamous cell carcinoma and promotes cancer progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10901070/
  61. Feb 2024
  62. link.springer.com link.springer.com
    CircUSP1 as a novel marker promotes gastric cancer progression via stabilizing HuR to upregulate USP1 and Vimentin
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    link.springer.com/article/10.1038/s41388-024-02968-8
  63. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Pyruvate dehydrogenase kinase 2 knockdown restores the ability of amyotrophic lateral sclerosis-linked SOD1G93A rat astrocytes to support motor neuron survival by increasing mitochondrial respiration
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    onlinelibrary.wiley.com/doi/10.1002/glia.24516
  64. www.sciencedirect.com www.sciencedirect.com
    De novo variants in DENND5B cause a neurodevelopmental disorder
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    sciencedirect.com/science/article/pii/S0002929724000338
  65. Jan 2024
  66. www.sciencedirect.com www.sciencedirect.com
    PARP5A and RNF146 phase separation restrains RIPK1-dependent necroptosis
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  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-molecule imaging of stochastic interactions that drive dynein activation and cargo movement in cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10798859/
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    Type 2 cytokine signaling in macrophages protects from cellular senescence and organismal aging
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  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lipopolysaccharide-induced sepsis impairs M2R-GIRK signaling in the mouse sinoatrial node
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    ncbi.nlm.nih.gov/pmc/articles/PMC10334783/
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    Simulated altitude is medicine: intermittent exposure to hypobaric hypoxia and cold accelerates injured skeletal muscle recovery
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    physoc.onlinelibrary.wiley.com/doi/10.1113/JP285398
  71. Dec 2023
  72. www.sciencedirect.com www.sciencedirect.com
    Isolation and characterization of small extracellular vesicles from murine primary mammary tumor
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    sciencedirect.com/science/article/pii/S2666166723007505
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    Purkinje-cell-specific MeCP2 deficiency leads to motor deficits and autistic-like behavior due to aberrations in PTP1B-TrkB-SK signaling
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    sciencedirect.com/science/article/pii/S2211124723015711
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    ChREBP is activated by reductive stress and mediates GCKR-associated metabolic traits
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    sciencedirect.com/science/article/pii/S1550413123004217
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lupeol synergizes with 5-Fluorouracil to combat c-MET/EphA2 mediated chemoresistance in triple negative breast cancer.
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    ncbi.nlm.nih.gov/pmc/articles/PMC10692664/
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    Autophagy is involved in degradation of AQP1 in response to an acute decrement in tonicity
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    sciencedirect.com/science/article/pii/S2589004223025622
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    Purification and characterization of different proteasome species from mammalian cells
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    sciencedirect.com/science/article/pii/S2666166723007153
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Arginase-1 in Plasma-Derived Exosomes as Marker of Metastasis in Patients with Head and Neck Squamous Cell Carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10670520/
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MiR-138-5p Upregulation during Neuronal Maturation Parallels with an Increase in Neuronal Survival
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    ncbi.nlm.nih.gov/pmc/articles/PMC10671628/
  80. Nov 2023
  81. www.sciencedirect.com www.sciencedirect.com
    PAK1-dependent mechanotransduction enables myofibroblast nuclear adaptation and chromatin organization during fibrosis
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    sciencedirect.com/science/article/pii/S2211124723014262
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    Active growth signaling promotes senescence and cancer cell sensitivity to CDK7 inhibition
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    sciencedirect.com/science/article/pii/S1097276523008547
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    BACH1 regulates the differentiation of vascular smooth muscle cells from human embryonic stem cells via CARM1-mediated methylation of H3R17
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    sciencedirect.com/science/article/pii/S2211124723014808
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    Circadian clock factors regulate the first condensation reaction of fatty acid synthesis in Arabidopsis
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    sciencedirect.com/science/article/pii/S221112472301495X
  85. www.nature.com www.nature.com
    Trans-vaccenic acid reprograms CD8+ T cells and anti-tumour immunity
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    nature.com/articles/s41586-023-06749-3
  86. link.springer.com link.springer.com
    SARS-CoV-2 ORF6 protein targets TRIM25 for proteasomal degradation to diminish K63-linked RIG-I ubiquitination and type-I interferon induction
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    link.springer.com/article/10.1007/s00018-023-05011-3
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fat- and sugar-induced signals regulate sweet and fat taste perception in Drosophila
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    ncbi.nlm.nih.gov/pmc/articles/PMC11212107/
  88. link.springer.com link.springer.com
    Human Wharton’s jelly-derived mesenchymal stromal cells promote bone formation in immunodeficient mice when administered into a bone microenvironment
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    link.springer.com/article/10.1186/s12967-023-04672-9
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hippocampus Insulin Receptors Regulate Episodic and Spatial Memory Through Excitatory/Inhibitory Balance
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    ncbi.nlm.nih.gov/pmc/articles/PMC10621302/
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    Sequencing-based functional assays for classification of BRCA2 variants in mouse ESCs
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    sciencedirect.com/science/article/pii/S2667237523002928
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    Pharmacological depletion of RNA splicing factor RBM39 by indisulam synergizes with PARP inhibitors in high-grade serous ovarian carcinoma
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    sciencedirect.com/science/article/pii/S2211124723013190
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    CD300f immune receptor contributes to healthy aging by regulating inflammaging, metabolism, and cognitive decline
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  93. Oct 2023
  94. www.embopress.org www.embopress.org
    The HACE1 E3 ligase mediates RAC1-dependent control of mTOR signaling complexes
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