513 Matching Annotations
  1. Feb 2022
  2. www.sciencedirect.com www.sciencedirect.com
    A combined cell and gene therapy approach for homotopic reconstruction of midbrain dopamine pathways using human pluripotent stem cells
    1
    1. scibot 18 Feb 2022
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      DOI: 10.1016/j.stem.2022.01.013

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    sciencedirect.com/science/article/pii/S1934590922000467
  3. www.embopress.org www.embopress.org
    LAMTOR1 inhibition of TRPML1-dependent lysosomal calcium release regulates dendritic lysosome trafficking and hippocampal neuronal function
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    1. scibot 12 Feb 2022
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      DOI: 10.15252/embj.2021108119

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    embopress.org/doi/abs/10.15252/embj.2021108119
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    Deceleration of the cell cycle underpins a switch from proliferative to terminal divisions in plant stomatal lineage
    2
    1. scibot 11 Feb 2022
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      DOI: 10.1016/j.devcel.2022.01.014

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    2. scibot 11 Feb 2022
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      DOI: 10.1016/j.devcel.2022.01.014

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    sciencedirect.com/science/article/pii/S1534580722000399
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    TRACE-seq: A transgenic system for unbiased and non-invasive transcriptome profiling of living cells
    2
    1. scibot 11 Feb 2022
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      DOI: 10.1016/j.isci.2022.103806

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    2. scibot 11 Feb 2022
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      DOI: 10.1016/j.isci.2022.103806

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    sciencedirect.com/science/article/pii/S2589004222000761
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    Epigenetic basis of oncogenic-Kras-mediated epithelial-cellular proliferation and plasticity
    2
    1. scibot 11 Feb 2022
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      DOI: 10.1016/j.devcel.2022.01.006

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    2. scibot 09 Feb 2022
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      DOI: 10.1016/j.devcel.2022.01.006

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    sciencedirect.com/science/article/pii/S1534580722000065
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    RAP80 suppresses the vulnerability of R-loops during DNA double-strand break repair
    1
    1. scibot 02 Feb 2022
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      DOI: 10.1016/j.celrep.2022.110335

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    sciencedirect.com/science/article/pii/S2211124722000511
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chemogenetic manipulation of microglia inhibits neuroinflammation and neuropathic pain in mice
    1
    1. scibot 02 Feb 2022
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      DOI: 10.1016/j.bbi.2020.11.030

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    ncbi.nlm.nih.gov/pmc/articles/PMC7897256/
  9. Jan 2022
  10. www.sciencedirect.com www.sciencedirect.com
    WEE1 kinase protects the stability of stalled DNA replication forks by limiting CDK2 activity
    1
    1. scibot 19 Jan 2022
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      DOI: 10.1016/j.celrep.2021.110261

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    sciencedirect.com/science/article/pii/S2211124721017733
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    Seipin localizes at endoplasmic-reticulum-mitochondria contact sites to control mitochondrial calcium import and metabolism in adipocytes
    1
    1. scibot 12 Jan 2022
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      DOI: 10.1016/j.celrep.2021.110213

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    sciencedirect.com/science/article/pii/S2211124721017174
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    NHR-80 senses the mitochondrial UPR to rewire citrate metabolism for lipid accumulation in Caenorhabditis elegans
    1
    1. scibot 12 Jan 2022
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      DOI: 10.1016/j.celrep.2021.110206

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    sciencedirect.com/science/article/pii/S2211124721017101
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    Identification and functional characterization of transcriptional activators in human cells
    1
    1. scibot 11 Jan 2022
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      DOI: 10.1016/j.molcel.2021.12.008

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    sciencedirect.com/science/article/pii/S1097276521010704
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    STING orchestrates the crosstalk between polyunsaturated fatty acid metabolism and inflammatory responses
    1
    1. scibot 05 Jan 2022
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      DOI: 10.1016/j.cmet.2021.12.007

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    sciencedirect.com/science/article/pii/S1550413121006264
  15. Dec 2021
  16. www.sciencedirect.com www.sciencedirect.com
    NAD kinase sustains lipogenesis and mitochondrial metabolismthrough fatty acid synthesis
    1
    1. scibot 29 Dec 2021
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      DOI: 10.1016/j.celrep.2021.110157

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    sciencedirect.com/science/article/pii/S2211124721016533
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    A brain-to-spinal sensorimotor loop for repetitive self-grooming
    1
    1. scibot 21 Dec 2021
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      DOI: 10.1016/j.neuron.2021.11.028

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    sciencedirect.com/science/article/pii/S0896627321009892
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    SARS-CoV-2 nucleocapsid protein binds host mRNAs and attenuates stress granules to impair host stress response
    1
    1. scibot 18 Dec 2021
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      DOI: 10.1016/j.isci.2021.103562

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    sciencedirect.com/science/article/pii/S2589004221015327
  19. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Retinal patterns and the cellular repertoire of neuropsin (Opn5) retinal ganglion cells
    1
    1. scibot 17 Dec 2021
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      DOI: 10.1002/cne.25272

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    onlinelibrary.wiley.com/doi/10.1002/cne.25272
  20. www.sciencedirect.com www.sciencedirect.com
    Suppression of MYC transcription activators by the immune cofactor NPR1 fine-tunes plant immune responses
    1
    1. scibot 15 Dec 2021
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      DOI: 10.1016/j.celrep.2021.110125

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    sciencedirect.com/science/article/pii/S2211124721016211
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    The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability
    1
    1. scibot 09 Dec 2021
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      DOI: 10.1016/j.celrep.2021.110080

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    sciencedirect.com/science/article/pii/S2211124721015710
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Silencing long ascending propriospinal neurons after spinal cord injury improves hindlimb stepping in the adult rat
    1
    1. scibot 08 Dec 2021
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      DOI: 10.7554/eLife.70058

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    ncbi.nlm.nih.gov/pmc/articles/PMC8639151/
  23. www.sciencedirect.com www.sciencedirect.com
    Closantel is an allosteric inhibitor of human Taspase1
    1
    1. scibot 08 Dec 2021
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      DOI: 10.1016/j.isci.2021.103524

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    sciencedirect.com/science/article/pii/S2589004221014954
  24. academic.oup.com academic.oup.com
    CAR-T cells Targeting TSHR Demonstrate Safety and Potent Preclinical Activity Against Differentiated Thyroid Cancer
    1
    1. scibot 06 Dec 2021
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      DOI: 10.1210/clinem/dgab819

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    academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgab819/6423845
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proximal and distal spinal neurons innervating multiple synergist and antagonist motor pools
    1
    1. scibot 04 Dec 2021
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      DOI: 10.7554/eLife.70858

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    ncbi.nlm.nih.gov/pmc/articles/PMC8631798/
  26. Nov 2021
  27. www.sciencedirect.com www.sciencedirect.com
    Gene regulatory networks controlling temporal patterning, neurogenesis, and cell-fate specification in mammalian retina
    1
    1. scibot 17 Nov 2021
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      DOI: 10.1016/j.celrep.2021.109994

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    sciencedirect.com/science/article/pii/S221112472101473X
  28. www.sciencedirect.com www.sciencedirect.com
    Arabidopsis ATXR2 represses de novo shoot organogenesis in the transition from callus to shoot formation
    1
    1. scibot 16 Nov 2021
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      DOI: 10.1016/j.celrep.2021.109980

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    sciencedirect.com/science/article/pii/S2211124721014595
  29. www.jneurosci.org www.jneurosci.org
    Frontotemporal Lobar Dementia Mutant Tau Impairs Axonal Transport through a Protein Phosphatase 1γ-Dependent Mechanism
    1
    1. scibot 13 Nov 2021
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      DOI: 10.1523/JNEUROSCI.1914-20.2021

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    jneurosci.org/content/41/45/9431
  30. www.sciencedirect.com www.sciencedirect.com
    A novel role of KEAP1/PGAM5 complex: ROS sensor for inducing mitophagy
    1
    1. scibot 12 Nov 2021
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      DOI: 10.1016/j.redox.2021.102186

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    sciencedirect.com/science/article/pii/S2213231721003463
  31. www.sciencedirect.com www.sciencedirect.com
    TIAM1-RAC1 promote small-cell lung cancer cell survival through antagonizing Nur77-induced BCL2 conformational change
    1
    1. scibot 10 Nov 2021
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      DOI: 10.1016/j.celrep.2021.109979

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    sciencedirect.com/science/article/pii/S2211124721014583
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    SENP1 in the retrosplenial agranular cortex regulates core autistic-like symptoms in mice
    1
    1. scibot 03 Nov 2021
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      DOI: 10.1016/j.celrep.2021.109939

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    sciencedirect.com/science/article/pii/S2211124721014121
  33. Oct 2021
  34. www.sciencedirect.com www.sciencedirect.com
    Turnover of fear engram cells by repeated experience
    1
    1. scibot 23 Oct 2021
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      DOI: 10.1016/j.cub.2021.10.004

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    sciencedirect.com/science/article/pii/S0960982221013580
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    DREAM represses distinct targets by cooperating with different THAP domain proteins
    1
    1. scibot 21 Oct 2021
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      DOI: 10.1016/j.celrep.2021.109835

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    sciencedirect.com/science/article/pii/S2211124721012997
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    A viral histone-like protein exploits antagonism between linker histones and HMGB proteins to obstruct the cell cycle
    1
    1. scibot 19 Oct 2021
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      DOI: 10.1016/j.cub.2021.09.050

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    sciencedirect.com/science/article/pii/S0960982221012902
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    Body-fat sensor triggers ribosome maturation in the steroidogenic gland to initiate sexual maturation in Drosophila
    1
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      DOI: 10.1016/j.celrep.2021.109830

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    sciencedirect.com/science/article/pii/S2211124721012948
  38. www.sciencedirect.com www.sciencedirect.com
    SHANK3 conformation regulates direct actin binding and crosstalk with Rap1 signaling
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      DOI: 10.1016/j.cub.2021.09.022

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    sciencedirect.com/science/article/pii/S0960982221012628
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    Spt4 facilitates the movement of RNA polymerase II through the +2 nucleosomal barrier
    1
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      DOI: 10.1016/j.celrep.2021.109755

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    sciencedirect.com/science/article/pii/S2211124721012092
  40. Sep 2021
  41. academic.oup.com academic.oup.com
    CRL4DTL E3 ligase induces degradation of the DNA replication initiation factor TICRR/TRESLIN specifically during S phase
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      DOI: 10.1093/nar/gkab805

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    academic.oup.com/nar/advance-article/doi/10.1093/nar/gkab805/6371977
  42. www.sciencedirect.com www.sciencedirect.com
    Reading ADP-ribosylation signaling using chemical biology and interaction proteomics
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      DOI: 10.1016/j.molcel.2021.08.037

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    sciencedirect.com/science/article/pii/S1097276521007176
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    Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imaging
    1
    1. scibot 21 Sep 2021
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      DOI: 10.1016/j.celrep.2021.109689

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    sciencedirect.com/science/article/pii/S2211124721011360
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuronal calmodulin levels are controlled by CAMTA transcription factors
    1
    1. scibot 18 Sep 2021
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      DOI: 10.7554/eLife.68238

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    ncbi.nlm.nih.gov/pmc/articles/PMC8428840/
  45. www.sciencedirect.com www.sciencedirect.com
    Myosin-X and talin modulate integrin activity at filopodia tips
    1
    1. scibot 16 Sep 2021
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      DOI: 10.1016/j.celrep.2021.109716

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    Alleviation of neuropathic pain by over-expressing a soluble colony-stimulating factor 1 receptor to suppress microgliosis and macrophage accumulation
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    The Rac-GAP alpha2-chimaerin signals via CRMP2 and stathmins in the development of the ocular motor system
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    SNF2 Family Protein Fft3 Suppresses Nucleosome Turnover to Promote Epigenetic Inheritance and Proper Replication
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    Cdc42 and its BORG2 and BORG3 effectors control the subcellular localization of septins between actin stress fibers and microtubules
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    Transformed Bone Marrow Cells Generate Neoplasms of Distinct Histogenesis. A Murine Model of Cancer Transplantation
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    Rapid Depletion of DIS3, EXOSC10, or XRN2 Reveals the Immediate Impact of Exoribonucleolysis on Nuclear RNA Metabolism and Transcriptional Control
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    Activity-Dependent Remodeling of Drosophila Olfactory Sensory Neuron Brain Innervation during an Early-Life Critical Period
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    Dynamic Palmitoylation Targets MAP6 to the Axon to Promote Microtubule Stabilization during Neuronal Polarization
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    Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development
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    The packing density of a supramolecular membrane protein cluster is controlled by cytoplasmic interactions
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    Cell‐ and region‐specific expression of depression‐related protein p11 (S100a10) in the brain
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    Onecut1 Is Essential for Horizontal Cell Genesis and Retinal Integrity
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    The expression of tubb2b undergoes a developmental transition in murine cortical neurons
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    A neuronal circuit that generates the temporal motor sequence for the defensive response in zebrafish larvae
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  104. Jun 2021
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    PCAF-Mediated Histone Acetylation Promotes Replication Fork Degradation by MRE11 and EXO1 in BRCA-Deficient Cells
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    Regulation of ARGONAUTE10 Expression Enables Temporal and Spatial Precision in Axillary Meristem Initiation in Arabidopsis
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    Ankmy2 Prevents Smoothened-Independent Hyperactivation of the Hedgehog Pathway via Cilia-Regulated Adenylyl Cyclase Signaling
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    Mitochondria Define Intestinal Stem Cell Differentiation Downstream of a FOXO/Notch Axis
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    Defined p16High Senescent Cell Types Are Indispensable for Mouse Healthspan
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    Neuronal Inactivity Co-opts LTP Machinery to Drive Potassium Channel Splicing and Homeostatic Spike Widening
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    Translation of GGC repeat expansions into a toxic polyglycine protein in NIID defines a novel class of human genetic disorders: the polyG diseases
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    Chronic loss of inhibition in piriform cortex following brief, daily optogenetic stimulation
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    Protocol for electron microscopy ultrastructural localization of the fusogenic lipid phosphatidic acid on plasma membrane sheets from chromaffin cells
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    Friendly mediates membrane depolarization-induced mitophagy in Arabidopsis
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    β-propeller proteins WDR45 and WDR45B regulate autophagosome maturation into autolysosomes in neural cells
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    Neuronal Nitric Oxide Synthase in Nucleus Accumbens Specifically Mediates Susceptibility to Social Defeat Stress through Cyclin-Dependent Kinase 5
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    SIRT2 promotes BRCA1-BARD1 heterodimerization through deacetylation
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  134. Mar 2021
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    An early cell shape transition drives evolutionary expansion of the human forebrain
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    Paradoxical activation of c-Src as a drug-resistant mechanism
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    Simultaneous binding of Guidance Cues NET1 and RGM blocks extracellular NEO1 signaling
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    DSB repair pathway choice is regulated by recruitment of 53BP1 through cell cycle-dependent regulation of Sp1
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  140. Feb 2021
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    Tissue-Specific DNA Repair Activity of ERCC-1/XPF-1
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    WNT Activates the AAK1 Kinase to Promote Clathrin-Mediated Endocytosis of LRP6 and Establish a Negative Feedback Loop
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    The PVN Enhances Cardiorespiratory Responses to Acute Hypoxia via Input to the nTS
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    An Epigenetic Priming Mechanism Mediated by Nutrient Sensing Regulates Transcriptional Output during C. elegans Development
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    Antidepressant drugs act by directly binding to TRKB neurotrophin receptors
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    Combined kinesin-1 and kinesin-3 activity drives axonal trafficking of TrkB receptors in Rab6 carriers
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  149. Jan 2021
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    Inhibition of p38 Mitogen–Activated Protein Kinase Ameliorates HAP40 Depletion–Induced Toxicity and Proteasomal Defect in Huntington’s Disease Model
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    Metoclopramide treatment blocks CD93-signaling-mediated self-renewal of chronic myeloid leukemia stem cells
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    Kinesin-4 KIF21B limits microtubule growth to allow rapid centrosome polarization in T cells
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    Variability of an Early Developmental Cell Population Underlies Stochastic Laterality Defects
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  154. Dec 2020
  155. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The mechanism of kinesin inhibition by kinesin-binding protein
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    RTEL1 Regulates G4/R-Loops to Avert Replication-Transcription Collisions
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    Concerted action of kinesins KIF5B and KIF13B promotes efficient secretory vesicle transport to microtubule plus ends
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  158. Nov 2020
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    The RIF1-long splice variant promotes G1 phase 53BP1 nuclear bodies to protect against replication stress
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    A Systematic Protein Turnover Map for Decoding Protein Degradation
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    The Deubiquitinating Enzyme Ataxin-3 Regulates Ciliogenesis and Phagocytosis in the Retina
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  162. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Subcellular mRNA Localization Regulates Ribosome Biogenesis in Migrating Cells
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  163. Oct 2020
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    Protocol for Proximity-Dependent Proteomic Profiling in Yeast Cells by APEX and Alk-Ph Probe
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    The dynamic interplay between ATP/ADP levels and autophagy sustain neuronal migration in vivo
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    Establishment and maintenance of motor neuron identity via temporal modularity in terminal selector function
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    Combinatorial Action of Temporally Segregated Transcription Factors
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  168. Sep 2020
  169. www.cell.com www.cell.com
    Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains
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    Mapping Cortical Integration of Sensory and Affective Pain Pathways
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    HMCES Maintains Replication Fork Progression and Prevents Double-Strand Breaks in Response to APOBEC Deamination and Abasic Site Formation
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    The GATA Transcription Factor Gaf1 Represses tRNAs, Inhibits Growth, and Extends Chronological Lifespan Downstream of Fission Yeast TORC1
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    LET-502/ROCK Regulates Endocytic Recycling by Promoting Activation of RAB-5 in a Distinct Subpopulation of Sorting Endosomes
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    Cortical anchoring of the microtubule cytoskeleton is essential for neuron polarity
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    Zinc Finger RNA-Binding Protein Zn72D Regulates ADAR-Mediated RNA Editing in Neurons
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    Co-expression of C9orf72 related dipeptide-repeats over 1000 repeat units reveals age- and combination-specific phenotypic profiles in Drosophila
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    Nef-Mediated CD3-TCR Downmodulation Dampens Acute Inflammation and Promotes SIV Immune Evasion
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  180. rupress.org rupress.org
    GRAF2, WDR44, and MICAL1 mediate Rab8/10/11–dependent export of E-cadherin, MMP14, and CFTR ΔF508
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    Systematic perturbation of retroviral LTRs reveals widespread long-range effects on human gene regulation
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    Viral Delivery of GDNF Promotes Functional Integration of Human Stem Cell Grafts in Parkinson’s Disease
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    Formation of Human Neuroblastoma in Mouse-Human Neural Crest Chimeras
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    Cycling Stem Cells Are Radioresistant and Regenerate the Intestine
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    UBP12 and UBP13 negatively regulate the activity of the ubiquitin-dependent peptidases DA1, DAR1 and DAR2
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    Mouse Heterochromatin Adopts Digital Compaction States without Showing Hallmarks of HP1-Driven Liquid-Liquid Phase Separation
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    Mono- and Poly-unsaturated Phosphatidic Acid Regulate Distinct Steps of Regulated Exocytosis in Neuroendocrine Cells
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    Targeted Kruppel-like factor 4 gene knockout in retinal ganglion cells improves visual function in multiple sclerosis mouse model
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    A Self-Organized PLT/Auxin/ARR-B Network Controls the Dynamics of Root Zonation Development in Arabidopsis thaliana
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    Tissue-Specific Regulation of the Wnt/β-Catenin Pathway by PAGE4 Inhibition of Tankyrase
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    A Kinesin adapter directly mediates dendritic mRNA localization during neural development in mice
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  196. www.cell.com www.cell.com
    AT-Hook Transcription Factors Restrict Petiole Growth by Antagonizing PIFs
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    Intraflagellar Transport Complex B Proteins Regulate the Hippo Effector Yap1 during Cardiogenesis
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    Partitioning of MLX-Family Transcription Factors to Lipid Droplets Regulates Metabolic Gene Expression
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    Genomic Profiling by ALaP-Seq Reveals Transcriptional Regulation by PML Bodies through DNMT3A Exclusion
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    DEAD Box Protein Family Member DDX28 Is a Negative Regulator of Hypoxia-Inducible Factor 2α- and Eukaryotic Initiation Factor 4E2-Directed Hypoxic Translation
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    BMP Signaling Gradient Scaling in the Zebrafish Pectoral Fin
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    Extranuclear Structural Components that Mediate Dynamic Chromosome Movements in Yeast Meiosis
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    AP‐3 vesicle uncoating occurs after HOPS‐dependent vacuole tethering
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    ESCO1 and CTCF enable formation of long chromatin loops by protecting cohesinSTAG1 from WAPL
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    The role of the diencephalon in the guidance of thalamocortical axons in mice
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  206. Jan 2020
  207. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    H3K9me2 orchestrates inheritance of spatial positioning of peripheral heterochromatin through mitosis
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    SAMHD1 Modulates Early Steps during Human Cytomegalovirus Infection by Limiting NF-κB Activation
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    Prevention and Reversion of Pancreatic Tumorigenesis through a Differentiation-Based Mechanism
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    IFI16 Targets the Transcription Factor Sp1 to Suppress HIV-1 Transcription and Latency Reactivation
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    Plasma Membrane Domain Patterning and Self-Reinforcing Polarity in Arabidopsis
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