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Jul 2021
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Active elimination of intestinal cells drives oncogenic growth in organoids

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1. scibot 07 Jul 2021
  
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  DOI: 10.1016/j.celrep.2021.109307
  
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sciencedirect.com/science/article/pii/S2211124721006835
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Microenvironmental innate immune signaling and cell mechanical responses promote tumor growth

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1. scibot 01 Jul 2021
  
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  DOI: 10.1016/j.devcel.2021.06.007
  
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sciencedirect.com/science/article/pii/S1534580721004858
Jun 2021
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The nuclear kinesin KIF18B promotes 53BP1-mediated DNA double-strand break repair

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1. scibot 30 Jun 2021
  
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  DOI: 10.1016/j.celrep.2021.109306
  
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sciencedirect.com/science/article/pii/S2211124721006823
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An Integrated Analysis of the Response of Colorectal Adenocarcinoma Caco-2 Cells to X-Ray Exposure

2
1. scibot 22 Jun 2021
  
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  DOI: 10.3389/fonc.2021.688919
  
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2. scibot 22 Jun 2021
  
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  DOI: 10.3389/fonc.2021.688919
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8209426/
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Polyploid mitosis and depolyploidization promote chromosomal instability and tumor progression in a Notch-induced tumor model

1
1. scibot 19 Jun 2021
  
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  DOI: 10.1016/j.devcel.2021.05.017
  
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sciencedirect.com/science/article/pii/S1534580721004779
May 2021
elifesciences.org elifesciences.org

Non-canonical Hedgehog signaling regulates spinal cord and muscle regeneration in Xenopus laevis larvae

1
1. scibot 26 May 2021
  
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  DOI: 10.7554/eLife.61804
  
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elifesciences.org/articles/61804
52.53.155.43 52.53.155.43

Pluripotent stem cell-derived endometrial stromal fibroblasts in a cyclic, hormone-responsive, coculture model of human decidua

1
1. scibot 19 May 2021
  
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  DOI: 10.1016/j.celrep.2021.109138
  
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52.53.155.43/f40d32d6a62a8044d7933749ef6ced8b983c9132/ssrn-5367484-html.html
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AHNAK controls 53BP1-mediated p53 response by restraining 53BP1 oligomerization and phase separation

1
1. scibot 09 May 2021
  
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  DOI: 10.1016/j.molcel.2021.04.010
  
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sciencedirect.com/science/article/pii/S1097276521003154
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HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis

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1. scibot 07 May 2021
  
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  DOI: 10.1016/j.molcel.2020.04.031
  
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sciencedirect.com/science/article/pii/S1097276520302732
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DNA Damage Promotes Epithelial Hyperplasia and Fate Mis-specification via Fibroblast Inflammasome Activation

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1. scibot 05 May 2021
  
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  DOI: 10.1016/j.devcel.2020.09.021
  
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sciencedirect.com/science/article/pii/S153458072030753X
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A Specialized Niche in the Pancreatic Microenvironment Promotes Endocrine Differentiation

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1. scibot 05 May 2021
  
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  DOI: 10.1016/j.devcel.2020.08.003
  
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sciencedirect.com/science/article/pii/S1534580720306274
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Defects in translation-dependent quality control pathways lead to convergent molecular and neurodevelopmental pathology

1
1. scibot 05 May 2021
  
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  DOI: 10.7554/eLife.66904
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8075583/
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Methionine restriction breaks obligatory coupling of cell proliferation and death by an oncogene Src in Drosophila

1
1. scibot 05 May 2021
  
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  DOI: 10.7554/eLife.59809
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8079150/
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Comprehensive Chromosome End Remodeling during Programmed DNA Elimination

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1. scibot 04 May 2021
  
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  DOI: 10.1016/j.cub.2020.06.058
  
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sciencedirect.com/science/article/pii/S0960982220309106
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The essential role of Dnmt1 in gametogenesis in the large milkweed bug Oncopeltus fasciatus

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1. scibot 01 May 2021
  
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  DOI: 10.7554/eLife.62202
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8064748/
Apr 2021
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Diversity in striatal synaptic circuits arises from distinct embryonic progenitor pools in the ventral telencephalon

1
1. scibot 28 Apr 2021
  
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  DOI: 10.1016/j.celrep.2021.109041
  
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sciencedirect.com/science/article/pii/S2211124721003570
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Cell intercalation driven by SMAD3 underlies secondary neural tube formation

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1. scibot 20 Apr 2021
  
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  DOI: 10.1016/j.devcel.2021.03.023
  
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sciencedirect.com/science/article/pii/S153458072100263X
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Topoisomerase IIα represses transcription by enforcing promoter-proximal pausing

1
1. scibot 14 Apr 2021
  
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  DOI: 10.1016/j.celrep.2021.108977
  
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sciencedirect.com/science/article/pii/S2211124721002916
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Arid1a-Plagl1-Hh signaling is indispensable for differentiation-associated cell cycle arrest of tooth root progenitors

1
1. scibot 07 Apr 2021
  
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  DOI: 10.1016/j.celrep.2021.108964
  
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sciencedirect.com/science/article/pii/S2211124721002783
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Cannibalized erythroblasts accelerate developmental neurogenesis by regulating mitochondrial dynamics

1
1. scibot 07 Apr 2021
  
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  DOI: 10.1016/j.celrep.2021.108942
  
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sciencedirect.com/science/article/pii/S2211124721002564
Mar 2021
elifesciences.org elifesciences.org

Age-related changes in polycomb gene regulation disrupt lineage fidelity in intestinal stem cells

1
1. scibot 28 Mar 2021
  
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  DOI: 10.7554/eLife.62250
  
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elifesciences.org/articles/62250
elifesciences.org elifesciences.org

Rapid changes in tissue mechanics regulate cell behaviour in the developing embryonic brain

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1. scibot 25 Mar 2021
  
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  DOI: 10.7554/eLife.39356
  
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elifesciences.org/articles/39356
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Integrin β1 coordinates survival and morphogenesis of the embryonic lineage upon implantation and pluripotency transition

1
1. scibot 10 Mar 2021
  
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  DOI: 10.1016/j.celrep.2021.108834
  
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sciencedirect.com/science/article/pii/S2211124721001480
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Spinal cord precursors utilize neural crest cell mechanisms to generate hybrid peripheral myelinating glia

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1. scibot 02 Mar 2021
  
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  DOI: 10.7554/eLife.64267
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7886336/
Feb 2021
www.cell.com www.cell.com

Drosophila female germline stem cells undergo mitosis without nuclear breakdown

1
1. scibot 25 Feb 2021
  
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  DOI: 10.1016/j.cub.2021.01.033
  
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cell.com/current-biology/fulltext/S0960-9822(21)00066-X
Jan 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Deletion of LRP1 From Astrocytes Modifies Neuronal Network Activity in an in vitro Model of the Tripartite Synapse

1
1. scibot 30 Jan 2021
  
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  DOI: 10.3389/fncel.2020.567253
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7842215/
www.embopress.org www.embopress.org

Steroid‐dependent switch of OvoL/Shavenbaby controls self‐renewal versus differentiation of intestinal stem cells

1
1. scibot 07 Jan 2021
  
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  DOI: 10.15252/embj.2019104347
  
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embopress.org/doi/full/10.15252/embj.2019104347
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A Disease-Causing Single Amino Acid Deletion in the Coiled-Coil Domain of RAD50 Impairs MRE11 Complex Functions in Yeast and Humans

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1. scibot 05 Jan 2021
  
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  DOI: 10.1016/j.celrep.2020.108559
  
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sciencedirect.com/science/article/pii/S2211124720315485
Dec 2020
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Regulatory T Cells Support Breast Cancer Progression by Opposing IFN-γ-Dependent Functional Reprogramming of Myeloid Cells

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1. scibot 15 Dec 2020
  
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  DOI: 10.1016/j.celrep.2020.108482
  
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sciencedirect.com/science/article/pii/S2211124720314716
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Excessive E2F Transcription in Single Cancer Cells Precludes Transient Cell-Cycle Exit after DNA Damage

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1. scibot 11 Dec 2020
  
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  DOI: 10.1016/j.celrep.2020.108449
  
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sciencedirect.com/science/article/pii/S2211124720314388
www.cell.com www.cell.com

Drosophila Tubulin-Specific Chaperone E Recruits Tubulin around Chromatin to Promote Mitotic Spindle Assembly

1
1. scibot 10 Dec 2020
  
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  DOI: 10.1016/j.cub.2020.11.009
  
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cell.com/current-biology/abstract/S0960-9822(20)31684-5
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Warburg-like Metabolic Reprogramming in Aging Intestinal Stem Cells Contributes to Tissue Hyperplasia

1
1. scibot 07 Dec 2020
  
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  DOI: 10.1016/j.celrep.2020.108423
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8011352/
Nov 2020
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Myt1 Kinase Couples Mitotic Cell Cycle Exit with Differentiation in Drosophila

1
1. scibot 26 Nov 2020
  
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  DOI: 10.1016/j.celrep.2020.108400
  
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sciencedirect.com/science/article/pii/S2211124720313899
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Sonic hedgehog signaling directs patterned cell remodeling during cranial neural tube closure

1
1. scibot 18 Nov 2020
  
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  DOI: 10.7554/eLife.60234
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7655103/
Oct 2020
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Molecular Fingerprint and Developmental Regulation of the Tegmental GABAergic and Glutamatergic Neurons Derived from the Anterior Hindbrain

1
1. scibot 21 Oct 2020
  
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  DOI: 10.1016/j.celrep.2020.108268
  
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Vascular dimorphism ensured by regulated proteoglycan dynamics favors rapid umbilical artery closure at birth

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Oxygen Tension and the VHL-Hif1α Pathway Determine Onset of Neuronal Polarization and Cerebellar Germinal Zone Exit

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Tead transcription factors differentially regulate cortical development

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A Regulatory Program for Initiation of Wnt Signaling during Posterior Regeneration

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The Septate Junction Protein Tsp2A Restricts Intestinal Stem Cell Activity via Endocytic Regulation of aPKC and Hippo Signaling

1
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Sox2‐dependent maintenance of mouse oligodendroglioma involves the Sox2‐mediated downregulation of Cdkn2b, Ebf1, Zfp423, and Hey2

1
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Vessel-derived angiocrine IGF-1 promotes Meckel's cartilage proliferation to drive jaw growth during embryogenesis

1
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  DOI: 10.1242/dev.190488
  
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Integrin-Mediated Focal Anchorage Drives Epithelial Zippering during Mouse Neural Tube Closure

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Nutrient-Driven O-GlcNAcylation Controls DNA Damage Repair Signaling and Stem/Progenitor Cell Homeostasis

1
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Intrauterine Pressures Adjusted by Reichert’s Membrane Are Crucial for Early Mouse Morphogenesis

1
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Crossover Position Drives Chromosome Remodeling for Accurate Meiotic Chromosome Segregation

1
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PRMT1-p53 Pathway Controls Epicardial EMT and Invasion

1
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Quantitative Analysis of 3D Tissue Deformation Reveals Key Cellular Mechanism Associated with Initial Heart Looping

1
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NCAM regulates temporal specification of neural progenitor cells via profilin2 during corticogenesisNCAM regulates temporal NPC specification

1
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  DOI: 10.1083/jcb.201902164
  
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A transient role of the ciliary gene Inpp5e in controlling direct versus indirect neurogenesis in cortical development

1
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Hox-dependent coordination of mouse cardiac progenitor cell patterning and differentiation

1
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  DOI: 10.7554/eLife.55124
  
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Clustered gamma-protocadherins regulate cortical interneuron programmed cell death

1
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Vibrio cholerae-Symbiont Interactions Inhibit Intestinal Repair in Drosophila

1
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Distinct Airway Epithelial Stem Cells Hide among Club Cells but Mobilize to Promote Alveolar Regeneration

1
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  DOI: 10.1016/j.stem.2019.12.014
  
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ATR Restrains DNA Synthesis and Mitotic Catastrophe in Response to CDC7 Inhibition

1
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Calorie Restriction Increases the Number of Competing Stem Cells and Decreases Mutation Retention in the Intestine

1
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  DOI: 10.1016/j.celrep.2020.107937
  
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L ARP7 Is a BRCA1 Ubiquitinase Substrate and Regulates Genome Stability and Tumorigenesis

1
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Essential Roles of Cohesin STAG2 in Mouse Embryonic Development and Adult Tissue Homeostasis

1
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Six3 and Six6 Are Jointly Required for the Maintenance of Multipotent Retinal Progenitors through Both Positive and Negative Regulation

1
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  DOI: 10.1016/j.celrep.2018.10.106
  
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cell.com/cell-reports/abstract/S2211-1247(18)31728-5
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Inducible Degradation of the Human SMC5/6 Complex Reveals an Essential Role Only during Interphase

1
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MKLP2 Is a Motile Kinesin that Transports the Chromosomal Passenger Complex during Anaphase

1
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  DOI: 10.1016/j.cub.2020.04.081
  
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Telophase correction refines division orientation in stratified epithelia

1
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  DOI: 10.7554/eLife.49249
  
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Direct Phosphorylation and Stabilization of MYC by Aurora B Kinase Promote T-cell Leukemogenesis

1
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Peroxisome Elevation Induces Stem Cell Differentiation and Intestinal Epithelial Repair

2
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A minimally sufficient model for rib proximal-distal patterning based on genetic analysis and agent-based simulations

1
1. scibot 04 Sep 2020
  
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  Anti-phospho-Histone H3
  
  DOI: 10.7554/eLife.29144
  
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Neurodevelopmental disorder risk gene DYRK1A is required for ciliogenesis and brain size in Xenopus embryos

1
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  phospho-histone H3
  
  DOI: 10.1242/dev.189290
  
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Jan 2020
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Neural stem cell temporal patterning and brain tumour growth rely on oxidative phosphorylation

1
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  DOI: 10.7554/eLife.47887
  
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Functionally Distinct Connectivity of Developmentally Targeted Striosome Neurons

1
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  RRID:AB_310177
  
  DOI: 10.1016/j.celrep.2019.09.076
  
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Coopted temporal patterning governs cellular hierarchy, heterogeneity and metabolism in Drosophila neuroblast tumors

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Heterogeneity within Stratified Epithelial Stem Cell Populations Maintains the Oral Mucosa in Response to Physiological Stress

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Environmental Oxygen Exposure Allows for the Evolution of Interdigital Cell Death in Limb Patterning

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GCNA Interacts with Spartan and Topoisomerase II to Regulate Genome Stability

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Genetic and Mechanical Regulation of Intestinal Smooth Muscle Development

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Redox Signaling via Lipid Peroxidation Regulates Retinal Progenitor Cell Differentiation

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Oncogenic MYC amplifies mitotic perturbations

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Pericentrin-mediated SAS-6 recruitment promotes centriole assembly

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Canonical Wnt5b Signaling Directs Outlying Nkx2.5+ Mesoderm into Pacemaker Cardiomyocytes

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Evolution of Ovipositor Length in Drosophila suzukii Is Driven by Enhanced Cell Size Expansion and Anisotropic Tissue Reorganization

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Mutations in ANKLE2, a ZIKA Virus Target, Disrupt an Asymmetric Cell Division Pathway in Drosophila Neuroblasts to Cause Microcephaly

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Embryonic progenitor pools generate diversity in fine-scale excitatory cortical subnetworks

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The COMPASS Family Protein ASH2L Mediates Corticogenesis via Transcriptional Regulation of Wnt Signaling

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Selective Killing of RAS-Malignant Tissues by Exploiting Oncogene-Induced DNA Damage

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Tight junction protein occludin regulates progenitor Self-Renewal and survival in developing cortex

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Control of Intestinal Cell Fate by Dynamic Mitotic Spindle Repositioning Influences Epithelial Homeostasis and Longevity

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Severe head dysgenesis resulting from imbalance between anterior and posterior ontogenetic programs

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3D Cellular Architecture Modulates Tyrosine Kinase Activity, Thereby Switching CD95-Mediated Apoptosis to Survival

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Recruitment of Adult Precursor Cells Underlies Limited Repair of the Infected Larval Midgut in Drosophila

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The Hippo Pathway Blocks Mammalian Retinal Müller Glial Cell Reprogramming

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Two Distinct E2F Transcriptional Modules Drive Cell Cycles and Differentiation

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Oncogenic Notch Triggers Neoplastic Tumorigenesis in a Transition-Zone-like Tissue Microenvironment

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Drug Screening in Human PSC-Cardiac Organoids Identifies Pro-proliferative Compounds Acting via the Mevalonate Pathway

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  DOI: 10.1016/j.celrep.2018.12.079
  
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Stem Cell Proliferation Is Kept in Check by the Chromatin Regulators Kismet/CHD7/CHD8 and Trr/MLL3/4

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Zika Virus Protease Cleavage of Host Protein Septin-2 Mediates Mitotic Defects in Neural Progenitors

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  DOI: 10.1016/j.neuron.2019.01.010
  
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De Novo PITX1 Expression Controls Bi-Stable Transcriptional Circuits to Govern Self-Renewal and Differentiation in Squamous Cell Carcinoma

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  DOI: 10.1016/j.immuni.2018.09.017
  
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The Divalent Metal Transporter 1 (DMT1) Is Required for Iron Uptake and Normal Development of Oligodendrocyte Progenitor Cells

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Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation

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A SoxB gene acts as an anterior gap gene and regulates posterior segment addition in a spider

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Dietary Lipids Modulate Notch Signaling and Influence Adult Intestinal Development and Metabolism in Drosophila

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Dual Roles of Poly(dA:dT) Tracts in Replication Initiation and Fork Collapse

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Evolution of Cortical Neurogenesis in Amniotes Controlled by Robo Signaling Levels

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Targeting p38α Increases DNA Damage, Chromosome Instability, and the Anti-tumoral Response to Taxanes in Breast Cancer Cells

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Cell-Specific Imd-NF-κB Responses Enable Simultaneous Antibacterial Immunity and Intestinal Epithelial Cell Shedding upon Bacterial Infection

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mTORC1 Activation during Repeated Regeneration Impairs Somatic Stem Cell Maintenance

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Nutritional Control of Stem Cell Division through S-Adenosylmethionine in Drosophila Intestine

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Cell death in neural precursor cells and neurons before neurite formation prevents the emergence of abnormal neural structures in the Drosophila optic lobe

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A Temporal Transcriptional Switch Governs Stem Cell Division, Neuronal Numbers, and Maintenance of Differentiation

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Nubbin isoform antagonism governs Drosophila intestinal immune homeostasis

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Insm1 Induces Neural Progenitor Delamination in Developing Neocortex via Downregulation of the Adherens Junction Belt-Specific Protein Plekha7

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Variant cell cycles regulated by Notch signaling control cell size and ensure a functional blood-brain barrier

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Differential Expression of NF2 in Neuroepithelial Compartments Is Necessary for Mammalian Eye Development

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mTORC1 Inactivation Promotes Colitis-Induced Colorectal Cancer but Protects from APC Loss-Dependent Tumorigenesis

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Mechanical Forces Program the Orientation of Cell Division during Airway Tube Morphogenesis

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Channel Nucleoporins Recruit PLK-1 to Nuclear Pore Complexes to Direct Nuclear Envelope Breakdown in C. elegans

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Effects of Exposure to the Endocrine-Disrupting Chemical Bisphenol A During Critical Windows of Murine Pituitary Development

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A Balance of Yki/Sd Activator and E2F1/Sd Repressor Complexes Controls Cell Survival and Affects Organ Size

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Transplantation of feeder‐free human induced pluripotent stem cell–derived cortical neuron progenitors in adult male Wistar rats with focal brain ischemia

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Cellular mechanisms of cyclophosphamide-induced taste loss in mice.

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CSNK1a1 Regulates PRMT1 to Maintain the Progenitor State in Self-Renewing Somatic Tissue

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Engineered Epidermal Progenitor Cells Can Correct Diet-Induced Obesity and Diabetes

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Mitosis can drive cell cannibalism through entosis

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RECQ5 Helicase Cooperates with MUS81 Endonuclease in Processing Stalled Replication Forks at Common Fragile Sites during Mitosis

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Histone Mutants Separate R Loop Formation from Genome Instability Induction

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Llgl1 Connects Cell Polarity with Cell-Cell Adhesion in Embryonic Neural Stem Cells

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Non-nuclear Pool of Splicing Factor SFPQ Regulates Axonal Transcripts Required for Normal Motor Development

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Amitosis of Polyploid Cells Regenerates Functional Stem Cells in the Drosophila Intestine

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Untitled document

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The Super Elongation Complex Drives Neural Stem Cell Fate Commitment

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Insulin Signaling Regulates the FoxM1/PLK1/CENP-A Pathway to Promote Adaptive Pancreatic β Cell Proliferation

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Time-Specific Effects of Spindle Positioning on Embryonic Progenitor Pool Composition and Adult Neural Stem Cell Seeding

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Induced Quiescence of Lgr5+ Stem Cells in Intestinal Organoids Enables Differentiation of Hormone-Producing Enteroendocrine Cells

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Cell Cycle-dependent Changes in Localization and Phosphorylation of the Plasma Membrane Kv2.1 K+ Channel Impact Endoplasmic Reticulum Membrane Contact Sites in COS-1 Cells

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Norrin/Frizzled4 signalling in the preneoplastic niche blocks medulloblastoma initiation

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Multi-organ Mapping of Cancer Risk

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LIX1 regulates YAP1 activity and controls the proliferation and differentiation of stomach mesenchymal progenitors

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Untitled document

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