1,345 Matching Annotations
  1. Jan 2024
  2. www.science.org www.science.org
    RHOAL57V drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling
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    LncRNA SNHG5 adversely governs follicular growth in PCOS via miR-92a-3p/CDKN1C axis
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    1. scibot 19 Jan 2024
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    Discrete prefrontal neuronal circuits determine repeated stress-induced behavioral phenotypes in male mice
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    sciencedirect.com/science/article/pii/S0896627323009340
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    Lymph node and tumor-associated PD-L1+ macrophages antagonize dendritic cell vaccines by suppressing CD8+ T cells
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    ZFP281 controls transcriptional and epigenetic changes promoting mouse pluripotent state transitions via DNMT3 and TET1
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    miRNA-194-3p represses NF-κB in gliomas to attenuate iPSC genes and proneural to mesenchymal transition.
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    β-Caryophyllene Inhibits Endothelial Tube Formation by Modulating the Secretome of Hypoxic Lung Cancer Cells—Possible Role of VEGF Downregulation
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    1. scibot 18 Jan 2024
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    MIF modulates p38/ERK phosphorylation via MKP-1 induction in sarcoidosis
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    sciencedirect.com/science/article/pii/S2589004223028237
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    Response to Bruton’s tyrosine kinase inhibitors in aggressive lymphomas linked to chronic selective autophagy
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    Discovery of dual-active ethionamide boosters inhibiting the Mycobacterium tuberculosis ESX-1 secretion system
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    Chronic hypoxia stabilizes 3βHSD1 via autophagy suppression
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    Kinome-wide siRNA screen identifies a DCLK2-TBK1 oncogenic signaling axis in clear cell renal cell carcinoma
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    Identifying Transmembrane Interactions in Receptor Protein Tyrosine Phosphatase Homodimerization and Heterodimerization
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      DOI: 10.1007/978-1-0716-3569-8_13

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    Formate supplementation enhances anti-tumor CD8+ T cell fitness and efficacy of PD-1 blockade
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      DOI: 10.1158/2159-8290.CD-22-1301

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    Olgotrelvir, a dual inhibitor of SARS-CoV-2 Mpro and cathepsin L, as a standalone antiviral oral intervention candidate for COVID-19
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  17. www.biorxiv.org www.biorxiv.org
    Building synthetic biosensors using red blood cell proteins
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    biorxiv.org/content/10.1101/2023.12.16.571988v1
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    Inhibition of PRL2 upregulates PTEN and attenuates tumor growth in Tp53-deficient sarcoma and lymphoma mouse models
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  19. 52.53.155.43 52.53.155.43
    Mitochondria-ER contact mediated by MFN2-SERCA2 interaction supports CD8+ T cell metabolic fitness and function in tumors
    1
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    Cleavage of the pseudoprotease iRhom2 by the signal peptidase complex reveals an ER-to-nucleus signaling pathway
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    Mechanism of GW117 antidepressant action: melatonin receptor-mediated regulation of sleep rhythm
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    Loss of hepatic phosphoenolpyruvate carboxykinase 1 dysregulates metabolic responses to acute exercise but enhances adaptations to exercise training in mice
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  23. Dec 2023
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    Design, synthesis and mechanistic anticancer activity of new acetylated 5-aminosalicylate-thiazolinone hybrid derivatives
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    Distinct interactions stabilize EGFR dimers and higher-order oligomers in cell membranes
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    Ethanol induces replication fork stalling and membrane stress in immortalized laryngeal cells
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    The Crucial Role of Single-Stranded DNA Binding in Enhancing Sensitivity to DNA-Damaging Agents for Schlafen 11 and Schlafen 13
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    KDM5B predicts temozolomide-resistant subclones in glioblastoma
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    PRMT blockade induces defective DNA replication stress response and synergizes with PARP inhibition
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    ASCL1 characterizes adrenergic neuroblastoma via its pioneer function and cooperation with core regulatory circuit factors
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    Oral magnesium prevents acetaminophen-induced acute liver injury by modulating microbial metabolism
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    Choroid plexus mast cells drive tumor-associated hydrocephalus
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    Autophagy supports PDGFRA-dependent brain tumor development by enhancing oncogenic signaling
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    MeCP2 represses the activity of topoisomerase IIβ in long neuronal genes
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    Combinatorial immune refocusing within the influenza hemagglutinin RBD improves cross-neutralizing antibody responses
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    Proximity extracellular protein-protein interaction analysis of EGFR using AirID-conjugated fragment of antigen binding
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    PI3K signaling promotes formation of lipid-laden foamy macrophages at the spinal cord injury site
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    Generation of the Human iPSC line from spontaneous Late-Onset Alzheimer’s disease patient with ApoE3/3 genotype and Sex-, Age-, and ApoE-Matched healthy control
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    pERK-mediated IL8 secretion can enhance the migration, invasion, and cisplatin resistance of CD10-positive oral cancer cells
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    Anti-tumor effects of chemically modified miR-143 lipoplexes in a colorectal cancer pelvic recurrence mouse model are mediated via downregulation of myristoylated alanine-rich C kinase substrate
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    In silico analysis and theratyping of an ultra-rare CFTR genotype (W57G/A234D) in primary human rectal and nasal epithelial cells
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    Generation of a CRISPR/Cas9-edited Plakoglobin (JUP)knock-out (JMUi001-A-4) iPSC line to model the cardiac phenotype of arrhythmogenic cardiomyopathy
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    Upregulation of Spinal MDGA1 in Rats After Nerve Injury Alters Interactions Between Neuroligin-2 and Postsynaptic Scaffolding Proteins and Increases GluR1 Subunit Surface Delivery in the Spinal Cord Dorsal Horn
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    Release of Histone H3K4-reading transcription factors from chromosomes in mitosis is independent of adjacent H3 phosphorylation
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    A Novel ASCT2 Inhibitor, C118P, Blocks Glutamine Transport and Exhibits Antitumour Efficacy in Breast Cancer
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    Synergistic antitumor efficacy of rMV-Hu191 and Olaparib in pancreatic cancer by generating oxidative DNA damage and ROS-dependent apoptosis
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    ASCL1-ERK1/2 Axis: ASCL1 restrains ERK1/2 via the dual specificity phosphatase DUSP6 to promote survival of a subset of neuroendocrine lung cancers
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    Haploinsufficiency of NFKBIA reshapes the epigenome antipodal to the IDH mutation and imparts disease fate in diffuse gliomas
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    New scaffolds for type II JAK2 inhibitors overcome the acquired G993A resistance mutation
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    The Stathmin-2 membrane targeting domain is required for axon protection and regulated degradation by DLK signaling
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