721 Matching Annotations
  1. Jul 2023
  2. www.sciencedirect.com www.sciencedirect.com
    Targeting phenylpyruvate restrains excessive NLRP3 inflammasome activation and pathological inflammation in diabetic wound healing
    1
    1. scibot 22 Jul 2023
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      DOI: 10.1016/j.xcrm.2023.101129

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    sciencedirect.com/science/article/pii/S2666379123002574
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    NAT10-mediated ac4C tRNA modification promotes EGFR mRNA translation and gefitinib resistance in cancer
    1
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      DOI: 10.1016/j.celrep.2023.112810

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    sciencedirect.com/science/article/pii/S2211124723008215
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    A lncRNA from the FTO locus acts as a suppressor of the m6A writer complex and p53 tumor suppression signaling
    1
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      DOI: 10.1016/j.molcel.2023.06.024

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    sciencedirect.com/science/article/pii/S1097276523004719
  5. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Cheng - Pharmacological targeting of Axin2 suppresses cell growth and metastasis in-html.html
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      DOI: 10.1111/bph.16193

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    52.53.155.43/51180316abfac9593501c4c683749a3ad6cad477/British J Pharmacology - 2023 - Cheng - Pharmacological targeting of Axin2 suppresses cell growth and metastasis in-html.html
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    Organ function is preserved despite reorganization of niche architecture in the hair follicle
    1
    1. scibot 12 Jul 2023
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      DOI: 10.1016/j.stem.2023.06.003

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    sciencedirect.com/science/article/pii/S193459092300214X
  7. www.nature.com www.nature.com
    Kinome-wide CRISPR-Cas9 knockout screens revealed PLK1 as a therapeutic target for osteosarcoma
    1
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      DOI: 10.1038/s41420-023-01526-7

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    nature.com/articles/s41420-023-01526-7
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    Perinatal ethanol exposure affects cell populations in adult dorsal hippocampal neurogenic niche
    1
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      DOI: 10.1016/j.neures.2023.07.001

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    sciencedirect.com/science/article/pii/S0168010223001360
  9. Jun 2023
  10. 52.53.155.43 52.53.155.43
    Individual glioblastoma cells harbor both proliferative and invasive capabilities during tumor progression
    1
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      DOI: 10.1093/neuonc/noad109

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    52.53.155.43/40a04ea0c744da51d1940ff4107c2876ed394ecb/noad109-html.html
  11. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Oligodendrocyte progenitor development from the postnatal rat subventricular zone is regulated by the p75 neurotrophin receptor
    1
    1. scibot 24 Jun 2023
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      DOI: 10.1002/glia.24430

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    onlinelibrary.wiley.com/doi/10.1002/glia.24430
  12. www.sciencedirect.com www.sciencedirect.com
    Ccdc85c-Par3 condensates couple cell polarity with Notch to control neural progenitor proliferation
    1
    1. scibot 24 Jun 2023
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      DOI: 10.1016/j.celrep.2023.112677

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    sciencedirect.com/science/article/pii/S2211124723006885
  13. www.sciencedirect.com www.sciencedirect.com
    Genetic lineage tracing reveals stellate cells as contributors to myofibroblasts in pancreas and islet fibrosis
    1
    1. scibot 09 Jun 2023
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    sciencedirect.com/science/article/pii/S2589004223010659
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deconstructing olfactory epithelium developmental pathways in olfactory neuroblastoma
    1
    1. scibot 08 Jun 2023
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      DOI: 10.1158/2767-9764.CRC-23-0013

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    ncbi.nlm.nih.gov/pmc/articles/PMC10243222/
  15. www.sciencedirect.com www.sciencedirect.com
    Targeted deprivation of methionine with engineered Salmonella leads to oncolysis and suppression of metastasis in broad types of animal tumor models
    1
    1. scibot 03 Jun 2023
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      DOI: 10.1016/j.xcrm.2023.101070

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    sciencedirect.com/science/article/pii/S2666379123001891
  16. aacrjournals.org aacrjournals.org
    Active remodeling of capillary endothelium via cancer cell-derived MMP9 promotes metastatic brain colonization
    1
    1. scibot 03 Jun 2023
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      DOI: 10.1158/0008-5472.CAN-22-3964

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    aacrjournals.org/cancerres/article/83/8/1299/725102/Active-Remodeling-of-Capillary-Endothelium-via
  17. aacrjournals.org aacrjournals.org
    HBx-induced HSPA8 stimulates HBV replication and suppresses ferroptosis to support liver cancer progression
    1
    1. scibot 03 Jun 2023
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      DOI: 10.1158/0008-5472.CAN-22-3169

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    aacrjournals.org/cancerres/article/83/7/1048/718997/HBx-Induced-HSPA8-Stimulates-HBV-Replication-and
  18. 52.53.155.43 52.53.155.43
    BPS Publications
    1
    1. scibot 03 Jun 2023
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      DOI: 10.1111/bph.16148

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    52.53.155.43/d27f51dc90424ab7a84267a030387579b7ccf608/British J Pharmacology - 2023 - Qiu - Complementary roles of EP2 and EP4 receptors in malignant glioma-html.html
  19. www.nature.com www.nature.com
    Medulloblastoma and high-grade glioma organoids for drug screening, lineage tracing, co-culture and in vivo assay
    1
    1. scibot 01 Jun 2023
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      DOI: 10.1038/s41596-023-00839-2

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    nature.com/articles/s41596-023-00839-2
  20. May 2023
  21. www.nature.com www.nature.com
    Pluripotent stem cell-derived committed cardiac progenitors remuscularize damaged ischemic hearts and improve their function in pigs
    1
    1. scibot 28 May 2023
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      DOI: 10.1038/s41536-023-00302-6

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    nature.com/articles/s41536-023-00302-6
  22. www.sciencedirect.com www.sciencedirect.com
    Single-cell transcriptomics of human-skin-equivalent organoids
    1
    1. scibot 17 May 2023
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      DOI: 10.1016/j.celrep.2023.112511

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    sciencedirect.com/science/article/pii/S2211124723005223
  23. www.sciencedirect.com www.sciencedirect.com
    Dichotomous ovarian cancer-initiating potential of Pax8+ cells revealed by a mouse genetic mosaic model
    1
    1. scibot 14 May 2023
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      DOI: 10.1016/j.isci.2023.106742

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    sciencedirect.com/science/article/pii/S2589004223008192
  24. www.sciencedirect.com www.sciencedirect.com
    Quantitative proteomic profiling identifies global protein network dynamics in murine embryonic heart development
    1
    1. scibot 06 May 2023
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      DOI: 10.1016/j.devcel.2023.04.011

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    sciencedirect.com/science/article/pii/S1534580723001818
  25. www.sciencedirect.com www.sciencedirect.com
    Age-dependent immune and lymphatic responses after spinal cord injury
    1
    1. scibot 06 May 2023
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      DOI: 10.1016/j.neuron.2023.04.011

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    sciencedirect.com/science/article/pii/S0896627323002969
  26. Apr 2023
  27. www.sciencedirect.com www.sciencedirect.com
    Kupffer-cell-derived IL-6 is repurposed for hepatocyte dedifferentiation via activating progenitor genes from injury-specific enhancers
    1
    1. scibot 27 Apr 2023
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      DOI: 10.1016/j.stem.2023.01.009

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    sciencedirect.com/science/article/pii/S1934590923000097
  28. www.sciencedirect.com www.sciencedirect.com
    UTP18-mediated p21 mRNA instability drives adenoma-carcinoma progression in colorectal cancer
    1
    1. scibot 26 Apr 2023
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      DOI: 10.1016/j.celrep.2023.112423

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    sciencedirect.com/science/article/pii/S2211124723004345
  29. www.sciencedirect.com www.sciencedirect.com
    Generation of left ventricle-like cardiomyocytes with improved structural, functional, and metabolic maturity from human pluripotent stem cells
    1
    1. scibot 26 Apr 2023
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      DOI: 10.1016/j.crmeth.2023.100456

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    sciencedirect.com/science/article/pii/S2667237523000759
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RAB27B Drives a Cancer Stem Cell Phenotype in NSCLC Cells Through Enhanced Extracellular Vesicle Secretion
    1
    1. scibot 20 Apr 2023
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      DOI: 10.1158/2767-9764.CRC-22-0425

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    ncbi.nlm.nih.gov/pmc/articles/PMC10109210/
  31. www.sciencedirect.com www.sciencedirect.com
    Identification of fibrocyte cluster in tumors reveals the role in antitumor immunity by PD-L1 blockade
    1
    1. scibot 20 Apr 2023
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      DOI: 10.1016/j.celrep.2023.112162

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    sciencedirect.com/science/article/pii/S2211124723001730
  32. www.sciencedirect.com www.sciencedirect.com
    YTHDF1 phase separation triggers the fate transition of spermatogonial stem cells by activating the IκB-NF-κB-CCND1 axis
    1
    1. scibot 15 Apr 2023
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      DOI: 10.1016/j.celrep.2023.112403

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    sciencedirect.com/science/article/pii/S221112472300414X
  33. www.sciencedirect.com www.sciencedirect.com
    Reversal of liver failure using a bioartificial liver device implanted with clinical-grade human-induced hepatocytes
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      DOI: 10.1016/j.stem.2023.03.013

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    sciencedirect.com/science/article/pii/S193459092300084X
  34. www.sciencedirect.com www.sciencedirect.com
    Synergistic effects of combined immunotherapy strategies in a model of multifocal hepatocellular carcinoma
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    sciencedirect.com/science/article/pii/S2666379123001192
  35. www.sciencedirect.com www.sciencedirect.com
    Positive selection of somatically mutated clones identifies adaptive pathways in metabolic liver disease
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    sciencedirect.com/science/article/abs/pii/S0092867423002751
  36. Mar 2023
  37. www.sciencedirect.com www.sciencedirect.com
    Polarity inversion reorganizes the stem cell compartment of the trophoblast lineage
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    sciencedirect.com/science/article/pii/S2211124723003248
  38. pathsocjournals.onlinelibrary.wiley.com pathsocjournals.onlinelibrary.wiley.com
    CDK4/6 inhibitor modulating active and quiescent intestinal stem cells for prevention of chemotherapy-induced diarrhea
    1
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      DOI: 10.1002/path.6078

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    pathsocjournals.onlinelibrary.wiley.com/doi/10.1002/path.6078
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Endothelial VEGFR Coreceptors Neuropilin-1 and Neuropilin-2 Are Essential for Tumor Angiogenesis
    1
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      DOI: 10.1158/2767-9764.CRC-22-0250

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    ncbi.nlm.nih.gov/pmc/articles/PMC10036134/
  40. www.sciencedirect.com www.sciencedirect.com
    PQBP1 regulates striatum development through balancing striatal progenitor proliferation and differentiation
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    sciencedirect.com/science/article/pii/S2211124723002887
  41. www.sciencedirect.com www.sciencedirect.com
    Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA ubiquitination
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    sciencedirect.com/science/article/pii/S2211124723003078
  42. www.sciencedirect.com www.sciencedirect.com
    Salmonella infection induces the reorganization of follicular dendritic cell networks concomitant with the failure to generate germinal centers
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    sciencedirect.com/science/article/pii/S2589004223003875
  43. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Cell proliferation and glial cell marker expression in the wall of the third ventricle in the tuberal region of the male mouse hypothalamus during postnatal development
    1
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      DOI: 10.1111/jne.13239

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    onlinelibrary.wiley.com/doi/10.1111/jne.13239
  44. www.embopress.org www.embopress.org
    Two Hippo signaling modules orchestrate liver size and tumorigenesis
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      DOI: 10.15252/embj.2022112126

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      DOI: 10.15252/embj.2022112126

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    embopress.org/doi/10.15252/embj.2022112126
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    In vivo RNA-seq and ChIP-seq analyses show an obligatory role for the C terminus of p53 in conferring tissue-specific radiation sensitivity
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    Bone metastasis initiation is coupled with bone remodeling through osteogenic differentiation of NG2+ cells
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    Prenatal low-dose methylmercury exposure causes premature neuronal differentiation and autism-like behaviors in a rodent model
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    S-adenosylmethionine blocks tumorigenesis and with immune checkpoint inhibitor enhances anti-cancer efficacy against BRAF mutant and wildtype melanomas
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    Reversibility and developmental neuropathology of linear nevus sebaceous syndrome caused by dysregulation of the RAS pathway
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    Augmenting Experimental Gastric Cancer Activity of Irinotecan through Liposomal Formulation and Antiangiogenic Combination Therapy
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    Pyruvate Kinase M2 Promotes Hair Regeneration by Connecting Metabolic and Wnt/β-Catenin Signaling
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    Deletion of Nox4 enhances remyelination following cuprizone-induced demyelination by increasing phagocytic capacity of microglia and macrophages in mice
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    Preservation effect of imeglimin on pancreatic β-cell mass: Noninvasive evaluation using 111In-exendin-4 SPECT/CT imaging and the perspective of mitochondrial involvements
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    NCOA4-mediated ferritinophagy is a pancreatic cancer dependency via maintenance of iron bioavailability for iron-sulfur cluster proteins
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    Transmembrane protein KIRREL1 regulates Hippo signaling via a feedback loop and represents a therapeutic target in YAP/TAZ-active cancers
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    The RNA helicase DDX5 cooperates with EHMT2 to sustain alveolar rhabdomyosarcoma growth
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    Mfsd2b and Spns2 are essential for maintenance of blood vessels during development and in anaphylactic shock
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  110. Jul 2022
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    Multifocal organoids reveal clonal associations between synchronous intestinal tumors with pervasive heterogeneous drug responses
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    PTEN and LKB1 are differentially required in Gli1-expressing mesenchymal cells to suppress gastrointestinal polyposis
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    Interferon-γ resistance and immune evasion in glioma develop via Notch-regulated co-evolution of malignant and immune cells
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    Ubiquitination and deubiquitination of 4E-T regulate neural progenitor cell maintenance and neurogenesis by controlling P-body formation
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    Small RNAs derived from tRNA fragmentation regulate the functional maturation of neonatal β cells
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    Beta-blockers disrupt mitochondrial bioenergetics and increase radiotherapy efficacy independently of beta-adrenergic receptors in medulloblastoma
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    Lanthionine Ketimine Ethyl Ester Accelerates Remyelination in a Mouse Model of Multiple Sclerosis - Jeffrey L. Dupree, Pablo M. Paez, Seema K. Tiwari-Woodruff, Travis T. Denton, Kenneth Hensley, Christina G. Angeliu, Anne I. Boullerne, Sergey Kalinin, Sophia Egge, Veronica T. Cheli, Giancarlo Denaroso, Kelley C. Atkinson, Micah Feri, Douglas L. Feinstein, 2022
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    Disruption of endosomal sorting in Schwann cells leads to defective myelination and endosomal abnormalities observed in Charcot-Marie-Tooth disease
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    Grafted human ESC-derived astroglia repair spinal cord injury via activation of host anti-inflammatory microglia in the lesion area
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    Progression Patterns in Non-Contrast-Enhancing Gliomas Support Brain Tumor Responsiveness to Surgical Lesions
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    Liver Endothelium Promotes HER3-mediated Cell Survival in Colorectal Cancer with Wild-type and Mutant KRAS
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    A pro-metastatic tRNA fragment drives Nucleolin oligomerization and stabilization of its bound metabolic mRNAs
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  126. May 2022
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    Heterochronic parabiosis induces stem cell revitalization and systemic rejuvenation across aged tissues
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    An injury-responsive Rac-to-Rho GTPase switch drives activation of muscle stem cells through rapid cytoskeletal remodeling
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    Bi-zonal cardiac engineered tissues with differential maturation features in a mid-throughput multimodal bioreactor
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    JAM-A Signals Through the Hippo Pathway to Regulate Intestinal Epithelial Proliferation
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    5-hydroxytryptamine produced by enteric serotonergic neurons initiates colorectal cancer stem cell self-renewal and tumorigenesis
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    Functional genetic screen identifies ITPR3/calcium/RELB axis as a driver of colorectal cancer metastatic liver colonization
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    RBPMS is an RNA-binding protein that mediates cardiomyocyte binucleation and cardiovascular development
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    miRNA/mRNA co-profiling identifies the miR-200 family as a central regulator of SMC quiescence
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    WWC proteins mediate LATS1/2 activation by Hippo kinases and imply a tumor suppression strategy
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    Microglia/macrophage-derived human CCL18 promotes glioma progression via CCR8-ACP5 axis analyzed in humanized slice model
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    Coactivator-associated arginine methyltransferase 1 controls oligodendrocyte differentiation in the corpus callosum during early brain development
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    A reversible metabolic stress-sensitive regulation of CRMP2A orchestrates EMT/stemness and increases metastatic potential in cancer
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    MYC Inhibition Halts Metastatic Breast Cancer Progression by Blocking Growth, Invasion, and Seeding
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    A genetic compensatory mechanism regulated by Jun and Mef2d modulates the expression of distinct class IIa Hdacs to ensure peripheral nerve myelination and repair
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    Acquired hydrocephalus is associated with neuroinflammation, progenitor loss, and cellular changes in the subventricular zone and periventricular white matter
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    Genetic resiliency associated with dominant lethal TPM1 mutation causing atrial septal defect with high heritability
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    miR-137 and miR-122, two outer subventricular zone non-coding RNAs, regulate basal progenitor expansion and neuronal differentiation
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    Epigenetic basis of oncogenic-Kras-mediated epithelial-cellular proliferation and plasticity
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    Histone Acetylation Defects in Brain Precursor Cells: A Potential Pathogenic Mechanism Causing Proliferation and Differentiation Dysfunctions in Mitochondrial Aspartate-Glutamate Carrier Isoform 1 Deficiency
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    Molecular dynamics and functional characterization of I37R-CFTR lasso mutation provide insights into channel gating activity
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    Nasal obstruction during the growth period modulates the Wnt/β-Catenin pathway and brain-derived neurotrophic factor production in association with tyrosine kinase receptor B mRNA reduction in mouse hippocampus
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  182. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  184. Nov 2021
  185. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Oligodendrocyte progenitor proliferation is disinhibited following traumatic brain injury in leukemia inhibitory factor heterozygous mice
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    Statins affect cancer cell plasticity with distinct consequences for tumor progression and metastasis
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    MiR-674-5p Suppresses the Proliferation and Migration of Glioma Cells by Targeting Cul4b
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    Hif-1a suppresses ROS-induced proliferation of cardiac fibroblasts following myocardial infarction
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  192. Oct 2021
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    H3K4 di-methylation governs smooth muscle lineage identity and promotes vascular homeostasis by restraining plasticity
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    Long noncoding RNA lnc-POP1-1 upregulated by VN1R5 promotes cisplatin resistance in head and neck squamous cell carcinoma through interaction with MCM5
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    The fate of notch-1 transcript is linked to cell cycle dynamics by activity of a natural antisense transcript
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    Microvessels support engraftment and functionality of human islets and hESC-derived pancreatic progenitors in diabetes models
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    UV-induced reduction in Polycomb repression promotes epidermal pigmentation
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  208. Aug 2021
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    Connexin 43 and Sonic Hedgehog Pathway Interplay in Glioblastoma Cell Proliferation and Migration
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    Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy
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    Transgenic modeling of Ndr2 gene amplification reveals disturbance of hippocampus circuitry and function
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    The Presynaptic Scaffold Protein Bassoon in Forebrain Excitatory Neurons Mediates Hippocampal Circuit Maturation: Potential Involvement of TrkB Signalling
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    Adrenomedullin ameliorates pulmonary fibrosis by regulating TGF-β-Smads signaling and myofibroblast differentiation
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    Conditional Deletion of the L-Type Calcium Channel Cav1.2 in Oligodendrocyte Progenitor Cells Affects Postnatal Myelination in Mice
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