Hypothesis

1,639 Matching Annotations

Jan 2025
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Distinct subcellular localization of tau and alpha-synuclein in lewy body disease

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1. scibot 24 Jan 2025
  
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  DOI: 10.1186/s40478-024-01913-w
  
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link.springer.com/article/10.1186/s40478-024-01913-w
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Synaptic vesicle endocytosis deficits underlie GBA-linked cognitive dysfunction in Parkinson’s disease and Dementia with Lewy bodies

9
1. scibot 24 Jan 2025
  
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  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
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2. scibot 23 Jan 2025
  
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  AB_839504
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_839504
3. scibot 22 Jan 2025
  
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  AB_839504
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_839504
4. scibot 21 Jan 2025
  
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  AB_839504
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_839504
5. scibot 20 Jan 2025
  
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  AB_839504
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_839504
6. scibot 19 Jan 2025
  
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  AB_839504
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_839504
7. scibot 18 Jan 2025
  
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  AB_839504
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_839504
8. scibot 17 Jan 2025
  
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  AB_839504
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:AB_839504
9. scibot 16 Jan 2025
  
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  AB_839504
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11527026/
www.cell.com www.cell.com

The microglial response to inhibition of Colony-stimulating-factor-1 receptor by PLX3397 differs by sex in adult mice

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  DOI: 10.1016/j.celrep.2024.115176
  
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cell.com/cell-reports/fulltext/S2211-1247(24)01527-4
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CD11c-Expressing Microglia Are Transient, Driven by Interactions With Apoptotic Cells

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1. scibot 24 Jan 2025
  
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  DOI: 10.1002/glia.24674
  
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onlinelibrary.wiley.com/doi/10.1002/glia.24674
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Changes in Circadian Rhythm in Chronically-Starved Mice Are Associated With Glial Cell Density Reduction in the Suprachiasmatic Nucleus

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1. scibot 24 Jan 2025
  
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  DOI: 10.1002/eat.24379
  
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onlinelibrary.wiley.com/doi/10.1002/eat.24379
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Persistently increased post-stress activity of paraventricular thalamic neurons is essential for the emergence of stress-induced alterations in behaviour

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1. scibot 23 Jan 2025
  
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  DOI: 10.1371/journal.pbio.3002962
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11750107/
elifesciences.org elifesciences.org

Unbiased identification of cell identity in dense mixed neural cultures

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1. scibot 18 Jan 2025
  
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  DOI: 10.7554/eLife.95273
  
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elifesciences.org/articles/95273
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Genetic Ablation of Sarm1 Mitigates Disease Acceleration after Traumatic Brain Injury in the SOD1G93A Transgenic Mouse Model of Amyotrophic Lateral Sclerosis

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1. scibot 17 Jan 2025
  
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  DOI: 10.1002/ana.27174
  
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onlinelibrary.wiley.com/doi/10.1002/ana.27174
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CRISPRi-based screens in iAssembloids to elucidate neuron-glia interactions

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1. scibot 16 Jan 2025
  
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  DOI: 10.1016/j.neuron.2024.12.016
  
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sciencedirect.com/science/article/pii/S0896627324009152
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Neuraminidase 1 regulates neuropathogenesis by governing the cellular state of microglia via modulation of Trem2 sialylation

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  DOI: 10.1016/j.celrep.2024.115204
  
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sciencedirect.com/science/article/pii/S2211124724015559
52.53.155.43 52.53.155.43

PDF-html.html

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1. scibot 08 Jan 2025
  
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  DOI: 10.1523/jneurosci.1508-24.2024
  
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52.53.155.43/f75a4d1b7b4b78af0fa5985b6038dce524eb3434/PDF-html.html
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<em>Journal of Neuroendocrinology</em> | BSN Journal | Wiley Online Library

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1. scibot 05 Jan 2025
  
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  DOI: 10.1111/jne.13480
  
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onlinelibrary.wiley.com/doi/10.1111/jne.13480
alz-journals.onlinelibrary.wiley.com alz-journals.onlinelibrary.wiley.com

Roles of blood monocytes carrying TREM2R47H mutation in pathogenesis of Alzheimer's disease and its therapeutic potential in APP/PS1 mice

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1. scibot 05 Jan 2025
  
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  DOI: 10.1002/alz.14402
  
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alz-journals.onlinelibrary.wiley.com/doi/full/10.1002/alz.14402
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Blood-derived APLP1+ extracellular vesicles are potential biomarkers for the early diagnosis of brain diseases

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1. scibot 04 Jan 2025
  
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  DOI: 10.1126/sciadv.ado6894
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11691634/
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Blood-derived APLP1+ extracellular vesicles are potential biomarkers for the early diagnosis of brain diseases

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  DOI: 10.1126/sciadv.ado6894
  
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science.org/doi/10.1126/sciadv.ado6894
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FUBP3 mediates the amyloid-β-induced neuronal NLRP3 expression

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1. scibot 03 Jan 2025
  
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  DOI: 10.4103/NRR.NRR-D-23-01799
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11691456/
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Role of immature choroid plexus in the pathology of model mice and human iPSC-derived organoids with autism spectrum disorder

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  DOI: 10.1016/j.celrep.2024.115133
  
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sciencedirect.com/science/article/pii/S2211124724014840
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Sex-specific astrocyte regulation of spinal motor circuits by Nkx6.1

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  DOI: 10.1016/j.celrep.2024.115121
  
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sciencedirect.com/science/article/pii/S2211124724014724
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Anti-herpetic tau preserves neurons via the cGAS-STING-TBK1 pathway in Alzheimer’s disease

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1. scibot 03 Jan 2025
  
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  DOI: 10.1016/j.celrep.2024.115109
  
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sciencedirect.com/science/article/pii/S2211124724014608
Dec 2024
www.cell.com www.cell.com

Hyperreactive B cells instruct their elimination by T cells to curb autoinflammation and lymphomagenesis

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1. scibot 29 Dec 2024
  
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  DOI: 10.1016/j.immuni.2024.11.023
  
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cell.com/immunity/abstract/S1074-7613(24)00538-7
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Human-induced pluripotent stem cell-derived microglia integrate into mouse retina and recapitulate features of endogenous microglia

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1. scibot 22 Dec 2024
  
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  DOI: 10.7554/eLife.90695
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11587526/
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Early‐life IL‐4 administration induces long‐term changes in microglia in the cerebellum and prefrontal cortex

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1. scibot 21 Dec 2024
  
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  DOI: 10.1111/jnc.16266
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11647562/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Pharmacological depletion of microglia protects against alcohol-induced corticolimbic neurodegeneration during intoxication in male rats

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1. scibot 21 Dec 2024
  
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  DOI: 10.1101/2024.11.04.621917
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11580899/
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Oral administration of Porphyromonas gingivalis to mice with diet-induced obesity impairs cognitive function associated with microglial activation in the brain

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1. scibot 21 Dec 2024
  
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  DOI: 10.1080/20002297.2024.2419155
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11565673/
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Protocol for immunofluorescence staining and large-scale analysis to quantify microglial cell morphology at single-cell resolution in mice

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1. scibot 21 Dec 2024
  
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  DOI: 10.1016/j.xpro.2024.103467
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11653134/
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Agarose hydrogel-mediated electroporation method for retinal tissue cultured at the air-liquid interface

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1. scibot 18 Dec 2024
  
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  DOI: 10.1016/j.isci.2024.111299
  
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sciencedirect.com/science/article/pii/S2589004224025240
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Phosphatidylserine Exposure Controls Viral Innate Immune Responses by Microglia

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1. scibot 17 Dec 2024
  
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  DOI: 10.1016/j.neuron.2016.12.021
  
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pmc.ncbi.nlm.nih.gov/articles/PMC5600182/
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Thrombin-induced kynurenine 3-monooxygenase causes variations in the kynurenine pathway, leading to neurological deficits in a murine intracerebral hemorrhage model

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1. scibot 14 Dec 2024
  
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  DOI: 10.1016/j.jphs.2024.12.003
  
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sciencedirect.com/science/article/pii/S1347861324000793
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Single-Nucleus RNA Sequencing Reveals the Spatiotemporal Dynamics of Disease-Associated Microglia in Amyotrophic Lateral Sclerosis

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1. scibot 13 Dec 2024
  
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  DOI: 10.34133/research.0548
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11632836/
onlinelibrary.wiley.com onlinelibrary.wiley.com

Blood–brain barrier dysfunction in multiple system atrophy: A human postmortem study

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1. scibot 13 Dec 2024
  
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  AB_839
  
  DOI: 10.1111/neup.13021
  
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onlinelibrary.wiley.com/doi/10.1111/neup.13021
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Mast cells proliferate in the peri-hippocampal space during early development and modulate local and peripheral immune cells

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1. scibot 12 Dec 2024
  
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  DOI: 10.1016/j.devcel.2024.11.015
  
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GDF15-GFRAL signaling drives weight loss and lipid metabolism in mouse model of amyotrophic lateral sclerosis

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Tau accumulation induces microglial state alterations in Alzheimer’s disease model mice

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Human iPSC-derived myelinating organoids and globoid cells to study Krabbe disease

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1-s2.0-S2589004224027755-main-html.html

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Microglial lipid phosphatase SHIP1 limits complement-mediated synaptic pruning in the healthy developing hippocampus

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Characterizing and targeting glioblastoma neuron-tumor networks with retrograde tracing

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Longitudinal autophagy profiling of the mammalian brain reveals sustained mitophagy throughout healthy aging

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1-s2.0-S2589004224027433-main-html.html

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Integrative pathway analysis across humans and 3D cellular models identifies the p38 MAPK-MK2 axis as a therapeutic target for Alzheimer’s disease

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Persistence of spike protein at the skull-meninges-brain axis may contribute to the neurological sequelae of COVID-19

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Unveiling the physiological impact of ESCRT-dependent autophagosome closure by targeting the VPS37A ubiquitin E2 variant-like domain

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RASP: Optimal Single Puncta Detection in Complex Cellular Backgrounds

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Inhibiting AMPA receptor signaling in oligodendrocytes rescues synapse loss in a model of autoimmune demyelination

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Temporal dynamics of neurovascular unit changes following blood-brain barrier opening in the putamen of non-human primates

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Ethanol modulates astrocyte activation and neuroinflammation via miR-339/NLRP6 inflammasome signaling

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Clustering-independent estimation of cell abundances in bulk tissues using single-cell RNA-seq data

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An accelerated Parkinson's disease monkey model using AAV-α-synuclein plus poly(ADP-ribose)

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Sleep deprivation leads to non-adaptive alterations in sleep microarchitecture and amyloid-β accumulation in a murine Alzheimer model

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Microbiota-derived lysophosphatidylcholine alleviates Alzheimer’s disease pathology via suppressing ferroptosis

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Microglia depletion reduces human neuronal APOE4-related pathologies in a chimeric Alzheimer’s disease model

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Systemic inflammation accelerates neurodegeneration in a rat model of Parkinson’s disease overexpressing human alpha synuclein

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Molecular basis of neurodegeneration in a mouse model of Polr3-related disease

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Shifts in the spatiotemporal profile of inflammatory phenotypes of innate immune cells in the rat brain following acute intoxication with the organophosphate diisopropylfluorophosphate

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Targeting Catechol-O-Methyltransferase Induces Mitochondrial Dysfunction and Enhances the Efficacy of Radiotherapy in Glioma

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Accelerated remyelination and immune modulation by the EBI2 agonist 7α,25-dihydroxycholesterol analogue in the cuprizone model

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Mitochondrial transplantation confers protection against the effects of ischemic stroke by repressing microglial pyroptosis and promoting neurogenesis

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Dysregulated Cholinergic Signaling Inhibits Oligodendrocyte Maturation Following Demyelination

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BRG1 programs PRC2-complex repression and controls oligodendrocyte differentiation and remyelination

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SIV-specific antibodies protect against inflammasome-driven encephalitis in untreated macaques

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High-fat and High-sucrose Diet-induced Hypothalamic Inflammation Shows Sex Specific Features in Mice

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Exploring the reduction in aquaporin-4 and increased expression of ciliary neurotrophic factor with the frontal–striatal gliosis induced by chronic high-fat dietary stress

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Recording γ-secretase activity in living mouse brains

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Novel multitarget analgesic candidate SZV-1287 demonstrates potential disease-modifying effects in the monoiodoacetate-induced osteoarthritis mouse model

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Compound (E)-2-(3,4-dihydroxystyryl)-3-hydroxy-4H-pyran-4-one downregulation of Galectin-3 ameliorates Aβ pathogenesis-induced neuroinflammation in 5 × FAD mice

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Exercise training upregulates CD55 to suppress complement-mediated synaptic phagocytosis in Parkinson’s disease

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Voluntary exercise suppresses inflammation and improves insulin resistance in the arcuate nucleus and ventral tegmental area in mice on a high-fat diet

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Modulation of cannabinoid receptor 2 alters neuroinflammation and reduces formation of alpha-synuclein aggregates in a rat model of nigral synucleinopathy

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Perfluoropentane-based oxygen-loaded nanodroplets reduce microglial activation through metabolic reprogramming

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Carboxy-terminal blockade of sortilin binding enhances progranulin gene therapy, a potential treatment for frontotemporal dementia

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Impact of O-GlcNAcylation elevation on mitophagy and glia in the dentate gyrus

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Reduced voluntary wheel running behaviour in Kiss1r knockout mice

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Implications of Developmental 17-OHPC Exposure on the Mesocorticolimbic Serotonergic and Dopaminergic Pathways and Adolescent Mood–Related Behavior in Rats

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Neuronal and glial cell alterations involved in the retinal degeneration of the familial dysautonomia optic neuropathy

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Exercise preconditioning alleviates ischemia-induced memory ... : Neural Regeneration Research

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Gut Microbiota–Metabolite–Brain Axis Reconstitution Reverses Sevoflurane-Induced Social and Synaptic Deficits in Neonatal Mice

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Simple and highly specific targeting of resident microglia with adeno-associated virus

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Loss of Collapsin Response Mediator Protein 4 Attenuates 6-Hydroxydopamine-Induced Impairments in a Mouse Model of Parkinson’s Disease

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Evans Blue Reduces Neuropathic Pain Behavior by Inhibiting Spinal ATP Release

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Nicotinamide phosphoribosyltransferase secreted from microglia via exosome during ischemic injury

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Untitled document

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CD47 Protects Synapses from Excess Microglia-Mediated Pruning during Development

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Genetic detection of Sonic hedgehog (Shh) expression and cellular response in the progression of acute through chronic demyelination and remyelination

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Microstructural and microglial changes after repetitive mild traumatic brain injury in mice

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Downregulation of Chloride voltage-gated channel 7 contributes to hyperalgesia following spared nerve injury

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Development of a 3-dimensional organotypic model with characteristics of peripheral sensory nerves

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Distinct tumor architectures and microenvironments for the initiation of breast cancer metastasis in the brain

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A p75 neurotrophin receptor-sparing nerve growth factor protects retinal ganglion cells from neurodegeneration by targeting microglia

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ATAXIN-2 intermediate-length polyglutamine expansions elicit ALS-associated metabolic and immune phenotypes

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Human iPSC-derived myelinating organoids and globoid cells to study Krabbe Disease

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Progesterone improves motor coordination impairments caused by postnatal hypoxic-ischemic brain insult in neonatal male rats

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Circulating platelets modulate oligodendrocyte progenitor cell differentiation during remyelination

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Circulating extracellular microRNAs in the blood promote sociability in mice

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SIRT1 improves lactate homeostasis in the brain to alleviate parkinsonism via deacetylation and inhibition of PKM2

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Neuropeptide Y receptor activation preserves inner retinal integrity through PI3K/Akt signaling in a glaucoma mouse model

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A glia-enriched stem cell 3D model of the human brain mimics the glial-immune neurodegenerative phenotypes of multiple sclerosis

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Oligodendrocyte precursor cell-derived exosomes combined with cell therapy promote clinical recovery by immunomodulation and gliosis attenuation

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Senescent cell clearance ameliorates temporal lobe epilepsy and associated spatial memory deficits in mice

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Elastin-like polypeptide delivery of anti-inflammatory peptides to the brain following ischemic stroke

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High-fat and high-sucrose diet-induced hypothalamic inflammation shows sex specific features in mice

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Definition of the contribution of an Osteopontin-producing CD11c<sup>+</sup> microglial subset to Alzheimer’s disease

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A TNF receptor 2 agonist ameliorates neuropathology and improves cognition in an Alzheimer’s disease mouse model

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Neuroprotection and Blood–Brain Barrier Restoration by Salubrinal After a Cortical Stab Injury

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Distinct subcellular localization of alternative splicing variants of EFA6D, a guanine nucleotide exchange factor for Arf6, in the mouse brain

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Cytogenesis in the adult monkey motor cortex: Perivascular NG2 cells are the major adult born cell type

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Absence of Apolipoprotein E is associated with exacerbation of prion pathology and promotes microglial neurodegenerative phenotype

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Plaque associated microglia hyper-secrete extracellular vesicles and accelerate tau propagation in a humanized APP mouse model

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  IBA1
  
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TRPV4 channels mediate the mechanoresponse in retinal microglia

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  rabbit anti‐Iba1
  
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Untitled document

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Untitled document

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Visual System Pathology in Humans and Animal Models of Blast Injury

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Glial activation in the periaqueductal gray promotes descending facilitation of neuropathic pain through the p38 MAPK signaling pathway

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The choroid plexus synergizes with immune cells during neuroinflammation

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Apocynin Prevents Cigarette Smoke-Induced Anxiety-Like Behavior and Preserves Microglial Profiles in Male Mice

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Cell-specific Nav1.6 knockdown reduced astrocyte-derived Aβ by reverse Na+-Ca2+ transporter-mediated autophagy in alzheimer-like mice

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Microglia rescue neurons from aggregate-induced neuronal dysfunction and death through tunneling nanotubes

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Movement-related increases in subthalamic activity optimize locomotion

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Innate immune training restores pro-reparative myeloid functions to promote remyelination in the aged central nervous system

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TERT activation targets DNA methylation and multiple aging hallmarks

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jp4c00174_si_001-html.html

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Table 1 Table of primary, and secondary antibodies and reagents used for immunohistochemical analysis

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Therapeutic potential of human microglia transplantation in a chimeric model of CSF1R-related leukoencephalopathy

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Loss of the polarity protein Par3 promotes dendritic spine neoteny and enhances learning and memory

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NF1-dependent disruption of the blood-nerve-barrier is improved by blockade of P2RY14

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Respiratory infection with influenza A virus delays remyelination and alters oligodendrocyte metabolism

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Effect of ultrasound-mediated blood-spinal cord barrier opening on survival and motor function in females in an amyotrophic lateral sclerosis mouse model

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The effects of time restricted feeding on age-related changes in the mouse retina

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Semaphorin 6D tunes amygdalar circuits for emotional, metabolic, and inflammatory outputs

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Immune Checkpoint Inhibition-related Neuroinflammation Disrupts Cognitive Function

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Lipid Nanoparticle-Mediated Delivery of mRNA Into the Mouse and Human Retina and Other Ocular Tissues

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Microglia are dispensable for experience-dependent refinement of mouse visual circuitry

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Immunosuppression-induced Zika virus reactivation causes brain inflammation and behavioral deficits in mice

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A Rapid Method for Producing Adeno-Associated Viral Vectors Suitable for Transducing Rodent Neurons in vitro and in vivo

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RNAi-mediated silencing of SOD1 profoundly extends survival and functional outcomes in ALS mice

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CD11c-expressing microglia are transient, driven by interactions with apoptotic cells

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The angiotensin II receptors type 1 and 2 modulate astrocytes and their crosstalk with microglia and neurons in an in vitro model of ischemic stroke

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A novel preparation for histological analyses of intraventricular macrophages in the embryonic brain

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Botulinum neurotoxin serotype A inhibited ocular angiogenesis through modulating glial activation via SOCS3

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Chronic consequences of ischemic stroke: Profiling brain injury and inflammation in a mouse model with reperfusion

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Microglia protect against age-associated brain pathologies

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The brain microvasculature is a primary mediator of interferon-α neurotoxicity in human cerebral interferonopathies

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TNF-NF-κB-p53 axis restricts in vivo survival of hPSC-derived dopamine neurons

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Cell-autonomous role of leucine-rich repeat kinase in the protection of dopaminergic neuron survival

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Human SIRT5 variants with reduced stability and activity do not cause neuropathology in mice

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Antiretroviral treatment reveals a novel role for lysosomes in oligodendrocyte maturation

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DL-3-n-Butylphthalide Ameliorates Post-stroke Emotional Disorders by Suppressing Neuroinflammation and PANoptosis

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Direct comparison of Hoxb8-driven reporter distribution in the brains of four transgenic mouse lines: towards a spinofugal projection atlas

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Pain hypersensitivity is dependent on autophagy protein Beclin 1 in males but not females

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Repopulated microglia after pharmacological depletion decrease dendritic spine density in adult mouse brain

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Inhibition of reactive oxygen species production accompanying alternatively activated microglia by risperidone in a mouse ketamine model of schizophrenia

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Akap5 links synaptic dysfunction to neuroinflammatory signaling in a mouse model of infantile neuronal ceroid lipofuscinosis

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Human spinal GABA neurons alleviate spasticity and improve locomotion in rats with spinal cord injury

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Perinatal Western-style Diet Exposure associated with Decreased Microglial Counts throughout the Arcuate Nucleus of the Hypothalamus in Japanese Macaques

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Altered Hippocampal Activation in Seizure-Prone CACNA2D2 Knock-out Mice

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Acute intoxication with diisopropylfluorophosphate promotes cellular senescence in the adult male rat brain

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SARS-CoV-2 infection exacerbates the cellular pathology of Parkinson’s disease in human dopaminergic neurons and a mouse model

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Viral mimicry and memory deficits upon microglial deletion of ATRX

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Menaquinone-4 Alleviates Neurological Deficits Associated with Intracerebral Hemorrhage by Preserving Corticospinal Tract in Mice

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The gut-brain and gut-macrophage contribution to gastrointestinal dysfunction with systemic inflammation

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Adult-Onset Deletion of ATP13A2 in Mice Induces Progressive Nigrostriatal Pathway Dopaminergic Degeneration and Lysosomal Abnormalities

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Ultraflexible electrodes for recording neural activity in the mouse spinal cord during motor behavior

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Adeno-associated viruses for efficient gene expression in the axolotl nervous system

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Repurposing ibudilast to mitigate Alzheimer’s disease by targeting inflammation

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Microglial CMPK2 promotes neuroinflammation and brain injury after ischemic stroke

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4-Hydroxybenzoic acid rescues multisystemic disease and perinatal lethality in a mouse model of mitochondrial disease

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Nurr1 overexpression in the primary motor cortex alleviates motor dysfunction induced by intracerebral hemorrhage in the striatum in mice

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Valproic Acid Treatment after Traumatic Brain Injury in Mice Alleviates Neuronal Death and Inflammation in Association with Increased Plasma Lysophosphatidylcholines

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Lesion-induced impairment of therapeutic capacities of olfactory ensheathing cells in an autologous transplantation model for treatment of spinal cord injury

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Cell autonomous role of leucine-rich repeat kinase in protection of dopaminergic neuron survival

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Small-molecule-induced epigenetic rejuvenation promotes SREBP condensation and overcomes barriers to CNS myelin regeneration

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Mice Mutated in the First Fibronectin Domain of Adhesion Molecule L1 Show Brain Malformations and Behavioral Abnormalities

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Truncated GPNMB, a microglial transmembrane protein, serves as a scavenger receptor for oligomeric β-amyloid peptide1-42 in primary type 1 microglia

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4R-cembranoid suppresses glial cells inflammatory phenotypes and prevents hippocampal neuronal loss in LPS-treated mice

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5Z-7-Oxozaenol attenuates cuprizone-induced demyelination in mice through microglia polarization regulation

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Lycium barbarum glycopeptide (wolfberry extract) slows N-methyl-N-nitrosourea-induced degradation of photoreceptors

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Growth hormone promotes myelin repair after chronic hypoxia via triggering pericyte-dependent angiogenesis

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Identification of hypoxic macrophages in glioblastoma with therapeutic potential for vasculature normalization

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Surface electrical stimulation of the auditory cortex preserves efferent medial olivocochlear neurons and reduces cochlear traits of age-related hearing loss

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LXR/CD38 activation drives cholesterol-induced macrophage senescence and neurodegeneration via NAD+ depletion

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Early amyloid-induced changes in microglia gene expression in male APP/PS1 mice

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Impact of cannabidiol on brain glucose metabolism of C57Bl/6 male mice previously exposed to cocaine

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Osteopontin drives neuroinflammation and cell loss in MAPT-N279K frontotemporal dementia patient neurons

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Microglia aging in the hippocampus advances through intermediate states that drive inflammatory activation and cognitive decline

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