313 Matching Annotations
  1. Aug 2021
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6316133/
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    cell.com/molecular-cell/abstract/S1097-2765(17)30607-X
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  5. elifesciences.org elifesciences.org
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    elifesciences.org/articles/31326
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    ncbi.nlm.nih.gov/pmc/articles/PMC6283279/
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    sciencedirect.com/science/article/pii/S1931312818305456
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  9. Jul 2021
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC5659757/
  11. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Vaccinia‐related kinase 2 modulates role of dysbindin by regulating protein stability
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14562
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    Parkin‐mediated ubiquitylation redistributes MITOL/March5 from mitochondria to peroxisomes
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    embopress.org/doi/full/10.15252/embr.201947728
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    PIAS1 Regulates Mutant Huntingtin Accumulation and Huntington’s Disease-Associated Phenotypes In Vivo
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    sciencedirect.com/science/article/pii/S0896627316300058
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    ncbi.nlm.nih.gov/pmc/articles/PMC5985145/
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Analysis of ubiquitin recognition by the HECT ligase E6AP provides insight into its linkage specificity
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    ncbi.nlm.nih.gov/pmc/articles/PMC6463701/
  20. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Quercetin improves the activity of the ubiquitin‐proteasomal system in 150Q mutated huntingtin‐expressing cells but exerts detrimental effects on neuronal survivability
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    onlinelibrary.wiley.com/doi/10.1002/jnr.23618/full
  21. rupress.org rupress.org
    Parkin-independent mitophagy via Drp1-mediated outer membrane severing and inner membrane ubiquitination
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    rupress.org/jcb/article/220/6/e202006043/211984/Parkin-independent-mitophagy-via-Drp1-mediated
  22. May 2021
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    The E3 ligase TRAF4 Promotes IGF Signaling by Mediating Atypical Ubiquitination of IRS-1
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    sciencedirect.com/science/article/pii/S0021925821005287
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    UBQLN2-HSP70 axis reduces poly-Gly-Ala aggregates and alleviates behavioral defects in the C9ORF72 animal model
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    sciencedirect.com/science/article/pii/S0896627321002890
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    Ubiquitin Phosphorylation at Thr12 Modulates the DNA Damage Response
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    sciencedirect.com/science/article/pii/S109727652030647X
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    Opposing roles of E3 ligases TRIM23 and TRIM21 in regulation of ion channel ANO1 protein levels
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    sciencedirect.com/science/article/pii/S0021925821005275
  27. Apr 2021
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    Pathogenic GRM7 mutations associated with neurodevelopmental disorders impair axon outgrowth and presynaptic terminal development
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    jneurosci.org/content/41/11/2344
  29. Feb 2021
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    Ribosome Collision Is Critical for Quality Control during No-Go Decay
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    cell.com/molecular-cell/abstract/S1097-2765(17)30616-0
  31. Jan 2021
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    DNA and RNA Cleavage Complexes and Repair Pathway for TOP3B RNA- and DNA-Protein Crosslinks
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    sciencedirect.com/science/article/pii/S2211124720315588
  33. Dec 2020
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    Pulse-Chase Proteomics of the App Knockin Mouse Models of Alzheimer’s Disease Reveals that Synaptic Dysfunction Originates in Presynaptic Terminals
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  35. Nov 2020
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    A Selective Autophagy Pathway for Phase-Separated Endocytic Protein Deposits
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  37. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Neuronal surface P antigen (NSPA) modulates postsynaptic NMDAR stability through ubiquitination of tyrosine phosphatase PTPMEG
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    pubmed.ncbi.nlm.nih.gov/33158444/
  38. Sep 2020
  39. elifesciences.org elifesciences.org
    Stress-activated MAPK signaling controls fission yeast actomyosin ring integrity by modulating formin For3 levels
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    elifesciences.org/articles/57951
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    Schnyder corneal dystrophy-associated UBIAD1 inhibits ER-associated degradation of HMG CoA reductase in mice
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    elifesciences.org/articles/44396
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    N‐linked glycosylation of the mGlu7 receptor regulates the forward trafficking and transsynaptic interaction with Elfn1
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202001544R
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    Proteome Instability Is a Therapeutic Vulnerability in Mismatch Repair-Deficient Cancer
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    sciencedirect.com/science/article/pii/S1535610820300507
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    Differential regulation and targeting of estrogen receptor α turnover in invasive lobular breast carcinoma
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    academic.oup.com/endo/article/161/9/bqaa109/5866024
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    Specific Knockdown of α-Synuclein by Peptide-Directed Proteasome Degradation Rescued Its Associated Neurotoxicity
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    Auto-ubiquitination of NEDD4-1 Recruits USP13 to Facilitate Autophagy through Deubiquitinating VPS34
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    sciencedirect.com/science/article/pii/S2211124720301224
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    The Ubiquitin Ligase TRIP12 Limits PARP1 Trapping and Constrains PARP Inhibitor Efficiency
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    The Tumour Suppressor TMEM127 Is a Nedd4-Family E3 Ligase Adaptor Required by Salmonella SteD to Ubiquitinate and Degrade MHC Class II Molecules
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    Threonine ADP-Ribosylation of Ubiquitin by a Bacterial Effector Family Blocks Host Ubiquitination
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    Ubiquitination-dependent control of sexual differentiation in fission yeast
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    Expanded Coverage of the 26S Proteasome Conformational Landscape Reveals Mechanisms of Peptidase Gating
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    cell.com/cell-reports/abstract/S2211-1247(18)31081-7
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    The Proteasome Governs Fungal Morphogenesis via Functional Connections with Hsp90 and cAMP-Protein Kinase A Signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC7175089/
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    The Cyclopeptide Astin C Specifically Inhibits the Innate Immune CDN Sensor STING
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    cell.com/cell-reports/fulltext/S2211-1247(18)31888-6
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    An Allosteric Interaction Network Promotes Conformation State-Dependent Eviction of the Nas6 Assembly Chaperone from Nascent 26S Proteasomes
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    cell.com/cell-reports/fulltext/S2211-1247(18)31972-7
  54. genesdev.cshlp.org genesdev.cshlp.org
    Crosstalk between Lys63- and Lys11-polyubiquitin signaling at DNA damage sites is driven by Cezanne
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    genesdev.cshlp.org/content/33/23-24/1702.full
  55. insight.jci.org insight.jci.org
    The UPR preserves mature oligodendrocyte viability and function in adults by regulating autophagy of PLP
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    insight.jci.org/articles/view/132364
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    The FTLD Risk Factor TMEM106B Regulates the Transport of Lysosomes at the Axon Initial Segment of Motoneurons
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    Chaperone-Mediated Protein Disaggregation Triggers Proteolytic Clearance of Intra-nuclear Protein Inclusions
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    sciencedirect.com/science/article/pii/S2211124720306331
  58. Jan 2020
  59. www.embopress.org www.embopress.org
    Parkin‐mediated ubiquitylation redistributes MITOL/March5 from mitochondria to peroxisomes
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  60. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Diethyldithiocarbamate, an anti‐abuse drug, alleviates steatohepatitis and fibrosis in rodents through modulating lipid metabolism and oxidative stress
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14503
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    lncRNA Sensing of a Viral Suppressor of RNAi Activates Non-canonical Innate Immune Signaling in Drosophila
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    sciencedirect.com/science/article/pii/S1931312819306353
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    Autoinhibition Mechanism of the Ubiquitin-Conjugating Enzyme UBE2S by Autoubiquitination
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    sciencedirect.com/science/article/pii/S0969212619301704
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    Proteomics Links Ubiquitin Chain Topology Change to Transcription Factor Activation
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    HIV-1 Envelope Overcomes NLRP3-Mediated Inhibition of F-Actin Polymerization for Viral Entry
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    MST1 Negatively Regulates TNFα-Induced NF-κB Signaling through Modulating LUBAC Activity
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    Vaccinia‐related kinase 2 modulates role of dysbindin by regulating protein stability
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    The Late Endosomal Pathway Regulates the Ciliary Targeting of Tetraspanin Protein Peripherin 2
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    jneurosci.org/content/39/18/3376
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    The zinc fingers of the Small Optic Lobes (SOL) calpain bind polyubiquitin
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  85. Nov 2018
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    mTORC1-Regulated and HUWE1-Mediated WIPI2 Degradation Controls Autophagy Flux
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    Modular Organization and Assembly of SWI/SNF Family Chromatin Remodeling Complexes
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    Tyrosine Phosphorylation of Mitochondrial Creatine Kinase 1 Enhances a Druggable Tumor Energy Shuttle Pathway
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    BLM Potentiates c-Jun Degradation and Alters Its Function as an Oncogenic Transcription Factor
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    Determinants of the cytosolic turnover of mitochondrial intermembrane space proteins
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    mTORC1-Mediated Inhibition of 4EBP1 Is Essential for Hedgehog Signaling-Driven Translation and Medulloblastoma
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    iASPP Is an Antioxidative Factor and Drives Cancer Growth and Drug Resistance by Competing with Nrf2 for Keap1 Binding
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    Ubiquitination of ABCE1 by NOT4 in Response to Mitochondrial Damage Links Co-translational Quality Control to PINK1-Directed Mitophagy
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    Pharmacological Inhibition of the Ubiquitin Ligase RNF5 Rescues F508del-CFTR in Cystic Fibrosis Airway Epithelia
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    MPK3- and MPK6-Mediated ICE1 Phosphorylation Negatively Regulates ICE1 Stability and Freezing Tolerance in Arabidopsis
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    Human Neural Stem Cell Transplantation Rescues Functional Deficits in R6/2 and Q140 Huntington's Disease Mice
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    Replication Fork Slowing and Reversal upon DNA Damage Require PCNA Polyubiquitination and ZRANB3 DNA Translocase Activity
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  107. Nov 2017
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    Tetherin Suppresses Type I Interferon Signaling by Targeting MAVS for NDP52-Mediated Selective Autophagic Degradation in Human Cells
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    Ribosome Collision Is Critical for Quality Control during No-Go Decay
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    A Linear Diubiquitin-Based Probe for Efficient and Selective Detection of the Deubiquitinating Enzyme OTULIN
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    USP5/Leon deubiquitinase confines postsynaptic growth by maintaining ubiquitin homeostasis through Ubiquilin
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    Ubiquitination-Deficient Mutations in Human Piwi Cause Male Infertility by Impairing Histone-to-Protamine Exchange during Spermiogenesis
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    Aging Triggers Cytoplasmic Depletion and Nuclear Translocation of the E3 Ligase Mahogunin: A Function for Ubiquitin in Neuronal Survival
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    In Vivo Ubiquitin Linkage-type Analysis Reveals that the Cdc48-Rad23/Dsk2 Axis Contributes to K48-Linked Chain Specificity of the Proteasome
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    SINAT E3 Ligases Control the Light-Mediated Stability of the Brassinosteroid-Activated Transcription Factor BES1 in Arabidopsis
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