280 Matching Annotations
  1. Jan 2022
  2. www.sciencedirect.com www.sciencedirect.com
    Isolation and characterization of the immune cell fraction from murine brain tumor microenvironment
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    1. scibot 21 Jan 2022
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    sciencedirect.com/science/article/pii/S2666166721008121
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    Presynaptic mechanisms underlying GABAB-receptor-mediated inhibition of spontaneous neurotransmitter release
    1
    1. scibot 19 Jan 2022
      AddgeneCatalog # 12251

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    sciencedirect.com/science/article/pii/S2211124721017678
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    Autologous humanized mouse models of iPSC-derived tumors enable characterization and modulation of cancer-immune cell interactions
    1
    1. scibot 16 Jan 2022
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    sciencedirect.com/science/article/pii/S2667237521002307
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    Epigenetic regulation of ferroptosis via ETS1/miR-23a-3p/ACSL4 axis mediates sorafenib resistance in human hepatocellular carcinoma
    1
    1. scibot 04 Jan 2022
      plasmid_12251

      DOI: 10.1186/s13046-021-02208-x

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    link.springer.com/article/10.1186/s13046-021-02208-x
  6. Nov 2021
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    Soluble guanylate cyclase signalling mediates etoposide resistance in progressing small cell lung cancer
    1
    1. scibot 21 Nov 2021
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      DOI: 10.1038/s41467-021-26823-6

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    nature.com/articles/s41467-021-26823-6
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    Transcriptomic taxonomy and neurogenic trajectories of adult human, macaque, and pig hippocampal and entorhinal cells
    1
    1. scibot 19 Nov 2021
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    sciencedirect.com/science/article/pii/S0896627321008667
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    Production of human CAR-NK cells with lentiviral vectors and functional assessment in vitro
    1
    1. scibot 18 Nov 2021
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    sciencedirect.com/science/article/pii/S2666166721006626
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    TIAM1-RAC1 promote small-cell lung cancer cell survival through antagonizing Nur77-induced BCL2 conformational change
    1
    1. scibot 10 Nov 2021
      plasmid_12251

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    sciencedirect.com/science/article/pii/S2211124721014583
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    IRAK1-dependent Regnase-1-14-3-3 complex formation controls Regnase-1-mediated mRNA decay
    1
    1. scibot 05 Nov 2021
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      DOI: 10.7554/eLife.71966

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    ncbi.nlm.nih.gov/pmc/articles/PMC8553338/
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    Convergence of distinct signaling pathways on synaptic scaling to trigger rapid antidepressant action
    1
    1. scibot 03 Nov 2021
      Addgene, Cat# 12251

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    sciencedirect.com/science/article/pii/S2211124721013917
  13. Oct 2021
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    A synaptic temperature sensor for body cooling
    1
    1. scibot 21 Oct 2021
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    sciencedirect.com/science/article/pii/S0896627321007698
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A guide in lentiviral vector production for hard-to-transfect cells, using cardiac-derived c-kit expressing cells as a model system
    1
    1. scibot 02 Oct 2021
      RRID:Addgene_12251

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    ncbi.nlm.nih.gov/pmc/articles/PMC8478948/
  16. Sep 2021
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    Revisiting astrocyte to neuron conversion with lineage tracing in vivo
    1
    1. scibot 28 Sep 2021
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    sciencedirect.com/science/article/pii/S0092867421010527
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    Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imaging
    1
    1. scibot 21 Sep 2021
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    sciencedirect.com/science/article/pii/S2211124721011360
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HBO1-MLL interaction promotes AF4/ENL/P-TEFb-mediated leukemogenesis
    1
    1. scibot 04 Sep 2021
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      DOI: 10.7554/eLife.65872

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    ncbi.nlm.nih.gov/pmc/articles/PMC8387021/
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Parallel Reporter Assays Identify Altered Regulatory Role of rs684232 in Leading to Prostate Cancer Predisposition
    1
    1. scibot 04 Sep 2021
      RRID:Addgene_12251

      DOI: 10.3390/ijms22168792

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    ncbi.nlm.nih.gov/pmc/articles/PMC8395720/
  21. Aug 2021
  22. www.sciencedirect.com www.sciencedirect.com
    A subthreshold synaptic mechanism regulating BDNF expression and resting synaptic strength
    1
    1. scibot 15 Aug 2021
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    sciencedirect.com/science/article/pii/S2211124721008901
  23. elifesciences.org elifesciences.org
    HOXA9 promotes MYC-mediated leukemogenesis by maintaining gene expression for multiple anti-apoptotic pathways
    1
    1. scibot 15 Aug 2021
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      DOI: 10.7554/eLife.64148

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    elifesciences.org/articles/64148
  24. www.sciencedirect.com www.sciencedirect.com
    Synthesis and Degradation of Adenosine 5′-Tetraphosphate by Nicotinamide and Nicotinate Phosphoribosyltransferases
    1
    1. scibot 13 Aug 2021
      Plasmid_12251

      DOI: 10.1016/j.chembiol.2017.03.010

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    sciencedirect.com/science/article/pii/S2451945617300934
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    A flow cytometry-based assay for serological detection of anti-spike antibodies in COVID-19 patients
    1
    1. scibot 12 Aug 2021
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    sciencedirect.com/science/article/pii/S2666166721003786
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    1. scibot 12 Aug 2021
      Plasmid_12251

      DOI: 10.1016/j.cell.2016.12.036

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    ncbi.nlm.nih.gov/pmc/articles/PMC5679265/
  27. www.sciencedirect.com www.sciencedirect.com
    UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors
    1
    1. scibot 10 Aug 2021
      Plasmid_12251

      DOI: 10.1016/j.cell.2018.11.024

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    sciencedirect.com/science/article/pii/S0092867418315162
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    1
    1. scibot 10 Aug 2021
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    sciencedirect.com/science/article/pii/S1097276518309857
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    Interspecies Chimerism with Mammalian Pluripotent Stem Cells
    1
    1. scibot 06 Aug 2021
      Plasmid_12251

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    sciencedirect.com/science/article/pii/S0092867416317524
  30. Jul 2021
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    1. scibot 31 Jul 2021
      RRID:Addgene_12251

      DOI: 10.7554/eLife.43511

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    ncbi.nlm.nih.gov/pmc/articles/PMC6414201/
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6224479/
  33. link.springer.com link.springer.com
    Methods for Modulating the Pathway of NF-κB Using <IndexTerm ID="ITerm1">Short Hairpin RNA (ShRNA)</IndexTerm>
    1
    1. scibot 16 Jul 2021
      RRID:Addgene_12251

      DOI: 10.1007/978-1-0716-1669-7_6

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    link.springer.com/protocol/10.1007/978-1-0716-1669-7_6
  34. www.sciencedirect.com www.sciencedirect.com
    Active elimination of intestinal cells drives oncogenic growth in organoids
    1
    1. scibot 09 Jul 2021
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    sciencedirect.com/science/article/pii/S2211124721006835
  35. www.sciencedirect.com www.sciencedirect.com
    Regulation of NMDA receptor trafficking and gating by activity-dependent CaMKIIα phosphorylation of the GluN2A subunit
    1
    1. scibot 07 Jul 2021
      plasmid_12251

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    sciencedirect.com/science/article/pii/S2211124721007142
  36. Jun 2021
  37. www.sciencedirect.com www.sciencedirect.com
    Evaluation of glycolytic rates in human hematopoietic stem/progenitor cells after target gene depletion
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      RRID:Addgene_12251

      DOI: 10.1016/j.xpro.2021.100603

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    sciencedirect.com/science/article/pii/S2666166721003105
  38. www.sciencedirect.com www.sciencedirect.com
    Using the dCas9-KRAB system to repress gene expression in hiPSC-derived NGN2 neurons
    1
    1. scibot 04 Jun 2021
      Plasmid_12251

      DOI: 10.1016/j.xpro.2021.100580

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    sciencedirect.com/science/article/pii/S2666166721002872
  39. May 2021
  40. www.sciencedirect.com www.sciencedirect.com
    Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis
    1
    1. scibot 28 May 2021
      CAT#12251

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    sciencedirect.com/science/article/pii/S0092867421005729
  41. www.nature.com www.nature.com
    Neuron and astrocyte aggregation and sorting in three-dimensional neuronal constructs
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      DOI: 10.1038/s42003-021-02104-2

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    nature.com/articles/s42003-021-02104-2
  42. www.sciencedirect.com www.sciencedirect.com
    The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer
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    sciencedirect.com/science/article/pii/S009286742100502X
  43. www.sciencedirect.com www.sciencedirect.com
    Rab34 GTPase mediates ciliary membrane formation in the intracellular ciliogenesis pathway
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      DOI: 10.1016/j.cub.2021.04.075

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    sciencedirect.com/science/article/pii/S0960982221006229
  44. www.nature.com www.nature.com
    The oncogenic E3 ligase TRIP12 suppresses epithelial–mesenchymal transition (EMT) and mesenchymal traits through ZEB1/2
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      DOI: 10.1038/s41420-021-00479-z

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    nature.com/articles/s41420-021-00479-z
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural insight into SARS-CoV-2 neutralizing antibodies and modulation of syncytia
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    ncbi.nlm.nih.gov/pmc/articles/PMC8064868/
  46. www.eneuro.org www.eneuro.org
    FEZ1 forms complexes with CRMP1 and DCC to regulate axon and dendrite development
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      DOI: 10.1523/ENEURO.0193-20.2021

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    eneuro.org/content/8/2/ENEURO.0193-20.2021
  47. www.sciencedirect.com www.sciencedirect.com
    Role of Aberrant Spontaneous Neurotransmission in SNAP25-Associated Encephalopathies
    1
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    sciencedirect.com/science/article/pii/S0896627320308084
  48. www.sciencedirect.com www.sciencedirect.com
    HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis
    1
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      DOI: 10.1016/j.molcel.2020.04.031

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    sciencedirect.com/science/article/pii/S1097276520302732
  49. www.sciencedirect.com www.sciencedirect.com
    Targeted delivery of siRNAs against hepatocellular carcinoma-related genes by a galactosylated polyaspartamide copolymer
    1
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      DOI: 10.1016/j.jconrel.2020.11.020

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    sciencedirect.com/science/article/pii/S0168365920306696
  50. Apr 2021
  51. www.sciencedirect.com www.sciencedirect.com
    A Method for Conditional Regulation of Protein Stability in Native or Near-Native Form
    1
    1. scibot 28 Apr 2021
      Plasmid#12251

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    sciencedirect.com/science/article/pii/S2451945620303767
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    Genetically engineered myeloid cells rebalance the core immune suppression program in metastasis
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      DOI: 10.1016/j.cell.2021.02.048

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    sciencedirect.com/science/article/pii/S0092867421002373
  53. www.sciencedirect.com www.sciencedirect.com
    p53 is a central regulator driving neurodegeneration caused by C9orf72 poly(PR)
    1
    1. scibot 24 Apr 2021
      Addgene 12251

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    sciencedirect.com/science/article/pii/S0092867420317475
  54. www.sciencedirect.com www.sciencedirect.com
    High-Throughput Discovery and Characterization of Human Transcriptional Effectors
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      RRID:Addgene_12251

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    sciencedirect.com/science/article/pii/S0092867420315415
  55. www.sciencedirect.com www.sciencedirect.com
    A Genetic Map of the Response to DNA Damage in Human Cells
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    1. scibot 23 Apr 2021
      Addgene Cat# 12251

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    sciencedirect.com/science/article/pii/S0092867420306735
  56. www.sciencedirect.com www.sciencedirect.com
    Cancer Burden Is Controlled by Mural Cell-β3-Integrin Regulated Crosstalk with Tumor Cells
    1
    1. scibot 23 Apr 2021
      CAT#12251

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    sciencedirect.com/science/article/pii/S0092867420301471
  57. www.sciencedirect.com www.sciencedirect.com
    Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion
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    1. scibot 17 Apr 2021
      RRID:Addgene_12251

      DOI: 10.1016/j.ccell.2020.04.017

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    sciencedirect.com/science/article/pii/S1535610820302166
  58. www.sciencedirect.com www.sciencedirect.com
    The dystonia gene THAP1 controls DNA double-strand break repair choice
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    1. scibot 15 Apr 2021
      RRID:Addgene_12251

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    sciencedirect.com/science/article/pii/S109727652100229X
  59. Mar 2021
  60. www.sciencedirect.com www.sciencedirect.com
    H3.3-K27M drives neural stem cell-specific gliomagenesis in a human iPSC-derived model
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      RRID:Addgene_12251

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    sciencedirect.com/science/article/pii/S1535610821000490
  61. www.sciencedirect.com www.sciencedirect.com
    Amino acids-Rab1A-mTORC1 signaling controls whole-body glucose homeostasis
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    1. scibot 17 Mar 2021
      Addgene_12251

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    sciencedirect.com/science/article/pii/S2211124721001443
  62. www.sciencedirect.com www.sciencedirect.com
    A FLCN-TFE3 Feedback Loop Prevents Excessive Glycogenesis and Phagocyte Activation by Regulating Lysosome Activity
    1
    1. scibot 03 Mar 2021
      Plasmid_12251

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    sciencedirect.com/science/article/pii/S2211124720300668
  63. Feb 2021
  64. www.sciencedirect.com www.sciencedirect.com
    R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m6A/PFKP/LDHB axis
    1
    1. scibot 28 Feb 2021
      RRID:Addgene_12251

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    sciencedirect.com/science/article/pii/S1097276520309473
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The palmitoyl acyltransferase ZDHHC14 controls Kv1-family potassium channel clustering at the axon initial segment
    1
    1. scibot 27 Feb 2021
      RRID:Addgene_12251

      DOI: 10.7554/eLife.56058

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    ncbi.nlm.nih.gov/pmc/articles/PMC7685708/
  66. www.cell.com www.cell.com
    A Global Map of G Protein Signaling Regulation by RGS Proteins
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    1. scibot 24 Feb 2021
      Plasmid_12251

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    cell.com/cell/abstract/S0092-8674(20)31140-5
  67. www.sciencedirect.com www.sciencedirect.com
    Gαo is a major determinant of cAMP signaling in the pathophysiology of movement disorders
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    1. scibot 09 Feb 2021
      Addgene_12251

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    sciencedirect.com/science/article/pii/S2211124721000310
  68. Jan 2021
  69. www.sciencedirect.com www.sciencedirect.com
    Optimized protocol for gene editing in adipocytes using CRISPR-Cas9 technology
    1
    1. scibot 29 Jan 2021
      pMDLg/pRRE

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    sciencedirect.com/science/article/pii/S2666166721000149
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Further evidence supporting a potential role for ADH1B in obesity
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      RRID:Addgene_12251

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  71. www.sciencedirect.com www.sciencedirect.com
    Metoclopramide treatment blocks CD93-signaling-mediated self-renewal of chronic myeloid leukemia stem cells
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    1. scibot 27 Jan 2021
      pMDLg/pRRE

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    sciencedirect.com/science/article/pii/S2211124720316521
  72. www.sciencedirect.com www.sciencedirect.com
    FOS licenses early events in stem cell activation driving skeletal muscle regeneration
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      Addgene_12251

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    sciencedirect.com/science/article/pii/S2211124720316454
  73. Dec 2020
  74. www.sciencedirect.com www.sciencedirect.com
    Reduction of mNAT1/hNAT2 Contributes to Cerebral Endothelial Necroptosis and Aβ Accumulation in Alzheimer’s Disease
    1
    1. scibot 13 Dec 2020
      MDL plasmid

      DOI: 10.1016/j.celrep.2020.108447

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    sciencedirect.com/science/article/pii/S2211124720314364
  75. www.sciencedirect.com www.sciencedirect.com
    Excessive E2F Transcription in Single Cancer Cells Precludes Transient Cell-Cycle Exit after DNA Damage
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    1. scibot 11 Dec 2020
      RRID:Addgene_12251

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    sciencedirect.com/science/article/pii/S2211124720314388
  76. www.sciencedirect.com www.sciencedirect.com
    Multiple Alternative Promoters and Alternative Splicing Enable Universal Transcription-Based Logic Computation in Mammalian Cells
    1
    1. scibot 07 Dec 2020
      Plasmid_12251

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    sciencedirect.com/science/article/pii/S2211124720314261
  77. www.authorea.com www.authorea.com
    Estrogen receptor alpha inhibits mesenchymal and amoeboidal movement of liver cancer cell via G protein subunit alpha 12
    1
    1. scibot 07 Dec 2020
      plasmid_12251

      DOI: 10.22541/au.160624514.40941389/v1

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    authorea.com/users/378507/articles/494981-estrogen-receptor-alpha-inhibits-mesenchymal-and-amoeboidal-movement-of-liver-cancer-cell-via-g-protein-subunit-alpha-12
  78. Sep 2020
  79. www.sciencedirect.com www.sciencedirect.com
    Activation of CpG-Rich Promoters Mediated by MLL Drives MOZ-Rearranged Leukemia
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    1. scibot 30 Sep 2020
      Plasmid_12251

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    sciencedirect.com/science/article/pii/S221112472031189X
  80. www.jbc.org www.jbc.org
    Intramitochondrial proteostasis is directly coupled to α-synuclein and amyloid β1-42 pathologies
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      RRID:Addgene_12251

      DOI: 10.1074/jbc.RA119.011650

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    jbc.org/content/295/30/10138.long
  81. www.sciencedirect.com www.sciencedirect.com
    Rational Design of Allosteric and Selective Inhibitors of the Molecular Chaperone TRAP1
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      RRID:Addgene_12251

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    sciencedirect.com/science/article/pii/S2211124720304319
  82. www.frontiersin.org www.frontiersin.org
    A20 Restricts Inflammatory Response and Desensitizes Gingival Keratinocytes to Apoptosis
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    1. scibot 16 Sep 2020
      RRID:Addgene_12251

      DOI: 10.3389/fimmu.2020.00365

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    frontiersin.org/article/10.3389/fimmu.2020.00365/full
  83. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    FEBS Press
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      Addgene_12251

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  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Perturbation of base excision repair sensitizes breast cancer cells to APOBEC3 deaminase-mediated mutations
    1
    1. scibot 09 Sep 2020
      RRID:Addgene_12251

      DOI: 10.7554/eLife.51605

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    ncbi.nlm.nih.gov/pmc/articles/PMC6961979/
  85. www.sciencedirect.com www.sciencedirect.com
    NF45 and NF90 Regulate Mitotic Gene Expression by Competing with Staufen-Mediated mRNA Decay
    1
    1. scibot 03 Sep 2020
      AddgeneCat# 12251

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    sciencedirect.com/science/article/pii/S2211124720306136
  86. www.sciencedirect.com www.sciencedirect.com
    E2F-Family Members Engage the PIDDosome to Limit Hepatocyte Ploidy in Liver Development and Regeneration
    1
    1. scibot 03 Sep 2020
      Addgene plasmid#12251

      DOI: 10.1016/j.devcel.2019.12.016

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    sciencedirect.com/science/article/pii/S1534580719310391
  87. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Co-culture Systems of Drug-Treated Acute Myeloid Leukemia Cells and T Cells for In Vitro and In Vivo Study
    1
    1. scibot 03 Sep 2020
      pMDLg/pRRE

      DOI: 10.1016/j.xpro.2020.100097

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  88. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Flexible Usage and Interconnectivity of Diverse Cell Death Pathways Protect against Intracellular Infection
    1
    1. scibot 03 Sep 2020
      pMDLg/pRRE plasmid

      DOI: 10.1016/j.immuni.2020.07.004

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  89. www.sciencedirect.com www.sciencedirect.com
    Integrated Transcriptome and Network Analysis Reveals Spatiotemporal Dynamics of Calvarial Suturogenesis
    1
    1. scibot 02 Sep 2020
      pMDLg/pRRE

      DOI: 10.1016/j.celrep.2020.107871

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    sciencedirect.com/science/article/pii/S2211124720308524
  90. Jan 2020
  91. www.sciencedirect.com www.sciencedirect.com
    A CEP104-CSPP1 Complex Is Required for Formation of Primary Cilia Competent in Hedgehog Signaling
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_12251

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    sciencedirect.com/science/article/pii/S2211124719309222
  92. link.springer.com link.springer.com
    Upregulated MiR-9-5p Protects Against Inflammatory Response in Rats with Deep Vein Thrombosis <Emphasis Type="Italic">via</Emphasis> Inhibition of NF-κB p50
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_12251

      DOI: 10.1007/s10753-019-01031-z

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  93. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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      Addgene_12251

      DOI: 10.1016/j.cub.2018.08.060

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    sciencedirect.com/science/article/pii/S0960982218311448
  94. www.sciencedirect.com www.sciencedirect.com
    RbAp48 Protein Is a Critical Component of GPR158/OCN Signaling and Ameliorates Age-Related Memory Loss
    1
    1. scibot 13 Jan 2020
      Plasmid_12251

      DOI: 10.1016/j.celrep.2018.09.077

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    sciencedirect.com/science/article/pii/S2211124718315377
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    1. scibot 12 Jan 2020
      RRID:Addgene_12251

      DOI: 10.7554/eLife.43511

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    ncbi.nlm.nih.gov/pmc/articles/PMC6414201/