562 Matching Annotations
  1. Jan 2025
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Comprehensive analysis of H3K27me3 LOCKs under different DNA methylation contexts reveal epigenetic redistribution in tumorigenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11748335/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mechanical Strain of Corneal Epithelium Influences the Expression of Genes Implicated in Keratoconus
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    pmc.ncbi.nlm.nih.gov/articles/PMC11758933/
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NAC regulates metabolism and cell fate in intestinal stem cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11708876/
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Hira complex regulates Gli3R-dependent transcription in Hedgehog signaling and medulloblastoma cell growth and migration
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    pmc.ncbi.nlm.nih.gov/articles/PMC11697252/
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PKCα regulates the secretion of PDL1-carrying small extracellular vesicles in a p53-dependent manner
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    pmc.ncbi.nlm.nih.gov/articles/PMC11733117/
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Coordination of Focal Adhesion Nanoarchitecture and Dynamics in Mechanosensing for Cardiomyoblast Differentiation
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    pmc.ncbi.nlm.nih.gov/articles/PMC11758775/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Paradoxical dominant negative activity of an immunodeficiency-associated activating PIK3R1 variant
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    pmc.ncbi.nlm.nih.gov/articles/PMC11750134/
  9. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225001282-main-html.html
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    52.53.155.43/0f3e1821d662f2c3e040e9d907c5943319b4efcb/1-s2.0-S2589004225001282-main-html.html
  10. www.sciencedirect.com www.sciencedirect.com
    A thermoplastic chip for 2D and 3D correlative assays combining screening and high-resolution imaging of immune cell responses
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    sciencedirect.com/science/article/pii/S2667237525000013
  11. www.sciencedirect.com www.sciencedirect.com
    MFSD6 is an entry receptor for respiratory enterovirus D68
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    sciencedirect.com/science/article/pii/S1931312824004827
  12. www.sciencedirect.com www.sciencedirect.com
    1-s2.0-S2589004224027652-main-html.html
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    sciencedirect.com/science/article/pii/S2589004224027652
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Therapeutic potential of anti-ErbB3 chimeric antigen receptor natural killer cells against breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11698710/
  14. www.sciencedirect.com www.sciencedirect.com
    Targeted localization of the mother centrosome in CD8+ T cells undergoing asymmetric cell division promotes memory formation
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    sciencedirect.com/science/article/pii/S2211124724014785
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    Identification of a broad-inhibition influenza neuraminidase antibody from pre-existing memory B cells
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    sciencedirect.com/science/article/pii/S1931312824004670
  16. Dec 2024
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cell-Penetrating Peptide Enhances Tafazzin Gene Therapy in Mouse Model of Barth Syndrome
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    pmc.ncbi.nlm.nih.gov/articles/PMC11678443/
  18. www.cell.com www.cell.com
    Targeting P4HA1 promotes CD8+ T cell progenitor expansion toward immune memory and systemic anti-tumor immunity
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    cell.com/cancer-cell/abstract/S1535-6108(24)00476-8
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Convergence of autism proteins at the cilium
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    pmc.ncbi.nlm.nih.gov/articles/PMC11643032/
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Expanding GABAergic Neuronal Diversity in iPSC-Derived Disease Models
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    pmc.ncbi.nlm.nih.gov/articles/PMC11642846/
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Plasticity of Human Microglia and Brain Perivascular Macrophages in Aging and Alzheimer’s Disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11643149/
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Fibrosis‐Encapsulated Tumoroid, A Solid Cancer Assembloid Model for Cancer Research and Drug Screening
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    pmc.ncbi.nlm.nih.gov/articles/PMC11650424/
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Principles of CRISPR-Cas13 mismatch intolerance enable selective silencing of point-mutated oncogenic RNA with single-base precision
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    pmc.ncbi.nlm.nih.gov/articles/PMC11654686/
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Calceolarioside B inhibits SARS-CoV-2 Omicron BA.2 variant cell entry and modulates immune response
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    pmc.ncbi.nlm.nih.gov/articles/PMC11662824/
  25. www.sciencedirect.com www.sciencedirect.com
    The carbonyl nucleobase adduct M3Ade is a potent antigen for adaptive polyclonal MR1-restricted T cells
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    sciencedirect.com/science/article/pii/S107476132400534X
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Structural and functional alterations of neurons derived from sporadic Alzheimer’s disease hiPSCs are associated with downregulation of the LIMK1-cofilin axis
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11660640/
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Aberrant neurodevelopment in human iPS cell‐derived models of Alexander disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11660530/
  28. www.sciencedirect.com www.sciencedirect.com
    1-s2.0-S2589004224027937-main-html.html
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    sciencedirect.com/science/article/pii/S2589004224027937
  29. www.sciencedirect.com www.sciencedirect.com
    YTHDF2 promotes ATP synthesis and immune evasion in B cell malignancies
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    sciencedirect.com/science/article/pii/S0092867424013242
  30. 52.53.155.43 52.53.155.43
    Endoplasmic reticulum morphology regulation by RTN4 modulates neuronal regeneration by curbing luminal transport
    2
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    52.53.155.43/a5cd2a76f55670a4ac26cd7a0c2f7cbc81f1256c/Endoplasmic reticulum morphology regulation by RTN4 modulates neu-html.html
  31. Nov 2024
  32. www.sciencedirect.com www.sciencedirect.com
    Profound synthetic lethality between SMARCAL1 and FANCM
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    sciencedirect.com/science/article/pii/S1097276524008566
  33. www.sciencedirect.com www.sciencedirect.com
    Acute multi-level response to defective de novo chromatin assembly in S-phase
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    sciencedirect.com/science/article/pii/S1097276524008633
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Chromatin protein complexes involved in gene repression in lamina-associated domains
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    pmc.ncbi.nlm.nih.gov/articles/PMC11535540/
  35. Oct 2024
  36. www.sciencedirect.com www.sciencedirect.com
    Type I IFN drives unconventional IL-1β secretion in lupus monocytes
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    sciencedirect.com/science/article/pii/S1074761324004485
  37. www.biorxiv.org www.biorxiv.org
    Generation of a PARPi-sensitive homozygous BRCA1-methylated OVCAR8 cell line using targeted CRISPR gene editing
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    biorxiv.org/content/10.1101/2024.09.23.614644v1
  38. www.sciencedirect.com www.sciencedirect.com
    Protocol for the efficient and inducible generation of CRISPR-Cas9-edited human cortical neurons from the iCas9-iNgn2 hPSCs
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    sciencedirect.com/science/article/pii/S2666166724005173
  39. Sep 2024
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    P53-dependent hypusination of eIF5A affects mitochondrial translation and senescence immune surveillance
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    ncbi.nlm.nih.gov/pmc/articles/PMC11358140/
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SLC13A3 is a major effector downstream of activated β-catenin in liver cancer pathogenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11364541/
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Atlastin-1 regulates endosomal tubulation and lysosomal proteolysis in human cortical neurons
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    ncbi.nlm.nih.gov/pmc/articles/PMC11300884/
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Ribosome Assembly Factor LSG1 Interacts with Vesicle-Associated Membrane Protein-Associated Proteins (VAPs)
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    ncbi.nlm.nih.gov/pmc/articles/PMC11376406/
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EFFECTS OF ARYL HYDROCARBON RECEPTOR LIGAND TCDD ON HUMAN TROPHOBLAST CELL DEVELOPMENT
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    ncbi.nlm.nih.gov/pmc/articles/PMC11383004/
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuroendocrine Prostate Cancer Drivers SOX2 and BRN2 Confer Differential Responses to Imipridones ONC201, ONC206, and ONC212 in Prostate Cancer Cell Lines
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11383667/
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CD8α Structural Domains Enhance GUCY2C CAR-T Cell Efficacy
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    ncbi.nlm.nih.gov/pmc/articles/PMC11423665/
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Atrial fibrillation variant-to-gene prioritization through cross-ancestry eQTL and single-nucleus multiomic analyses
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    ncbi.nlm.nih.gov/pmc/articles/PMC11388022/
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SHANK3 depletion leads to ERK signalling overdose and cell death in KRAS-mutant cancers
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    ncbi.nlm.nih.gov/pmc/articles/PMC11393128/
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ligand requirements for immunoreceptor triggering
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    ncbi.nlm.nih.gov/pmc/articles/PMC11399299/
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Proteasome and Cul3-Dependent Protein Ubiquitination Is Required for Gli Protein-Mediated Activation of Gene Expression in the Hedgehog Pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC11394618/
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Exploring the transcriptional cooperation between RUNX2 and its associated elncRNA RAIN
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    ncbi.nlm.nih.gov/pmc/articles/PMC11399121/
  52. www.sciencedirect.com www.sciencedirect.com
    Targeting NAT10 inhibits osteosarcoma progression via ATF4/ASNS-mediated asparagine biosynthesis
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    sciencedirect.com/science/article/pii/S2666379124004555
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CCR2 cooperativity promotes hematopoietic stem cell homing to the bone marrow
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    ncbi.nlm.nih.gov/pmc/articles/PMC11409967/
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cancer cell stiffening via CoQ10 and UBIAD1 regulates ECM signaling and ferroptosis in breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11410950/
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GCN2 is a determinant of the response to WEE1 kinase inhibition in small-cell lung cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11407228/
  56. www.sciencedirect.com www.sciencedirect.com
    Targeting heterozygous dominant negative variant of KCNA2 using Gapmer antisense oligonucleotides (ASO) for the treatment of drug-resistant epilepsy
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    sciencedirect.com/science/article/pii/S2162253124002038
  57. www.sciencedirect.com www.sciencedirect.com
    Protocol to identify receptors of secreted proteins through CRISPR-Cas9 whole-genome screening technology
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    sciencedirect.com/science/article/pii/S2666166724004805
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RUVBL1/2 Blockade Targets YTHDF1 Activity to Suppress m6A-Dependent Oncogenic Translation and Colorectal Tumorigenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11372367/
  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mitigation of synaptic and memory impairments via F-actin stabilization in Alzheimer’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11380428/
  60. www.biorxiv.org www.biorxiv.org
    Inseparable/IER3IP1 are essential for cytokinesis in Drosophila neuroblast and human cells
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    biorxiv.org/content/10.1101/2024.07.20.604396v2
  61. Aug 2024
  62. www.sciencedirect.com www.sciencedirect.com
    Gemcitabine therapeutically disrupts essential SIRT1-mediated p53 repression in atypical teratoid/rhabdoid tumors
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    sciencedirect.com/science/article/pii/S266637912400421X
  63. www.sciencedirect.com www.sciencedirect.com
    Disruption of nuclear speckle integrity dysregulates RNA splicing in C9ORF72-FTD/ALS
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    sciencedirect.com/science/article/pii/S0896627324005701
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Engineering a “muco‐trapping” ACE2‐immunoglobulin hybrid with picomolar affinity as an inhaled, pan‐variant immunotherapy for COVID‐19
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    ncbi.nlm.nih.gov/pmc/articles/PMC11256170/
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    De Novo Multi-Omics Pathway Analysis Designed for Prior Data Independent Inference of Cell Signaling Pathways
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    ncbi.nlm.nih.gov/pmc/articles/PMC11259815/
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Evaluation of DNA minicircles for delivery of adenine and cytosine base editors using activatable gene on “GO” reporter imaging systems
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    ncbi.nlm.nih.gov/pmc/articles/PMC11260848/
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The molecular basis underlying T cell specificity towards citrullinated epitopes presented by HLA-DR4
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    ncbi.nlm.nih.gov/pmc/articles/PMC11266596/
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinctive In Vitro Phenotypes in iPSC-Derived Neurons From Patients With Gain- and Loss-of-Function SCN2A Developmental and Epileptic Encephalopathy
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    ncbi.nlm.nih.gov/pmc/articles/PMC10883610/
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Development of KoRV-pseudotyped lentiviral vectors for efficient gene transfer into freshly isolated immune cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11257948/
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The NR4A2/VGF pathway fuels inflammation-induced neurodegeneration via promoting neuronal glycolysis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11324305/
  71. www.sciencedirect.com www.sciencedirect.com
    Nuclear PKM2 binds pre-mRNA at folded G-quadruplexes and reveals their gene regulatory role
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    sciencedirect.com/science/article/pii/S1097276524006233
  72. www.sciencedirect.com www.sciencedirect.com
    Protocol for the application of single-cell damage in murine intestinal organoid models
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    sciencedirect.com/science/article/pii/S2666166724003186
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Peptidylarginine deiminase 3 modulates response to neratinib in HER2 positive breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11297914/
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Circular RNAs regulate neuron size and migration of midbrain dopamine neurons during development
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    ncbi.nlm.nih.gov/pmc/articles/PMC11310423/
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EphA3-targeted chimeric antigen receptor T cells are effective in glioma and generate curative memory T cell responses
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    ncbi.nlm.nih.gov/pmc/articles/PMC11308882/
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Novel Luciferase-Based Reporter Gene Technology for Simultaneous Optical and Radionuclide Imaging of Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11312113/
  77. 52.53.155.43 52.53.155.43
    Endoplasmic reticulum morphology regulation by RTN4 modulates neuronal regeneration by curbing luminal transport
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    52.53.155.43/a5cd2a76f55670a4ac26cd7a0c2f7cbc81f1256c/Endoplasmic reticulum morphology regulation by RTN4 modulates neu-html.html
  78. www.cell.com www.cell.com
    Early rhombic lip Protogenin+ve stem cells in a human-specific neurovascular niche initiate and maintain group 3 medulloblastoma
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    cell.com/cell/fulltext/S0092-8674(24)00651-2
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR/Cas9 screening reveals a distinct class of MHC-I binders with precise HLA-peptide recognition
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    ncbi.nlm.nih.gov/pmc/articles/PMC11209011/
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intercellular transfer of cancer cell invasiveness via endosome-mediated protease shedding
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    ncbi.nlm.nih.gov/pmc/articles/PMC10858897/
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acetylation-induced proteasomal degradation of the activated glucocorticoid receptor limits hormonal signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC10850750/
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Safety and feasibility of anti-CD19 CAR T cells expressing inducible IL-7 and CCL19 in patients with relapsed or refractory large B-cell lymphoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10774422/
  83. aacrjournals.org aacrjournals.org
    Targeting RNA exonuclease XRN1 potentiates efficacy of cancer immunotherapy
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    aacrjournals.org/cancerres/article/83/6/922/718565/Targeting-RNA-Exonuclease-XRN1-Potentiates
  84. www.researchsquare.com www.researchsquare.com
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    researchsquare.com/article/rs-7216019/'https://www.researchsquare.com/article/rs-7216019/v1
  85. Jul 2024
  86. www.sciencedirect.com www.sciencedirect.com
    ATAD1 prevents clogging of TOM and damage caused by un-imported mitochondrial proteins
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    sciencedirect.com/science/article/pii/S2211124724008027
  87. www.embopress.org www.embopress.org
    DUSP6 inhibition overcomes neuregulin/HER3-driven therapy tolerance in HER2+ breast cancer
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    embopress.org/doi/10.1038/s44321-024-00088-0
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DUSP6 inhibition overcomes neuregulin/HER3-driven therapy tolerance in HER2+ breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11251193/
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metformin synergizes with gilteritinib in treating FLT3-mutated leukemia via targeting PLK1 signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC11293342/
  90. www.cell.com www.cell.com
    SigmaR1 shapes rough endoplasmic reticulum membrane sheets
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    cell.com/developmental-cell/fulltext/S1534-5807(24)00382-4
  91. www.cell.com www.cell.com
    Genetic ablation of adhesion ligands mitigates rejection of allogeneic cellular immunotherapies
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    cell.com/cell-stem-cell/abstract/S1934-5909(24)00219-4
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    High-Throughput Discovery and Characterization of Viral Transcriptional Effectors in Human Cells
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  146. Mar 2024
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  185. Jan 2024
  186. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RBL2 represses the transcriptional activity of Multicilin to inhibit multiciliogenesis
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    PICH deficiency limits the progression of MYC-induced B-cell lymphoma
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  188. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Isolation and Characterization of Neutralizing Monoclonal Antibodies from a Large Panel of Murine Antibodies against RBD of the SARS-CoV-2 Spike Protein
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  189. www.sciencedirect.com www.sciencedirect.com
    EXO1 protects BRCA1-deficient cells against toxic DNA lesions
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    Selective gene expression maintains human tRNA anticodon pools during differentiation
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    PAPAS promotes differentiation of mammary epithelial cells and suppresses breast carcinogenesis
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  192. Dec 2023
  193. www.sciencedirect.com www.sciencedirect.com
    FEZ1 participates in human embryonic brain development by modulating neuronal progenitor subpopulation specification and migration
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    The MHC-E peptide ligands for checkpoint CD94/NKG2A are governed by inflammatory signals, whereas LILRB1/2 receptors are peptide indifferent
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    KDM5B predicts temozolomide-resistant subclones in glioblastoma
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    Rational optimization of a transcription factor activation domain inhibitor
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  197. Nov 2023
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    Copine-6 is a Ca2+ sensor for activity-induced AMPA receptor exocytosis
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    An integrated in vitro human iPSCs-derived neuron and in vivo animal approach for preclinical screening of anti-seizure compounds
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    Optimized peptide nanofibrils as efficient transduction enhancers for in vitro and ex vivo gene transfer
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    CRISPR/Cas9 screens unravel miR-3689a-3p regulating sorafenib resistance in hepatocellular carcinoma via suppressing CCS/SOD1-dependent mitochondrial oxidative stress
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  202. Oct 2023
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    Regulation of STING activity in DNA sensing by ISG15 modification
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    Sequential activation of E2F via Rb degradation and c-Myc drives resistance to CDK4/6 inhibitors in breast cancer
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    Preclinical development of a chimeric antigen receptor T cell therapy targeting FGFR4 in rhabdomyosarcoma
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    Chromatin-modifying enzymes as modulators of nuclear size during lineage differentiation
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