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Apr 2024
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Reciprocal inhibition between TP63 and STAT1 regulates anti-tumor immune response through interferon-γ signaling in squamous cancer

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1. scibot 15 Apr 2024
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10954759/
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METTL3 drives telomere targeting of TERRA lncRNA through m6A-dependent R-loop formation: a therapeutic target for ALT-positive neuroblastoma

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1. scibot 15 Apr 2024
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10954483/
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Sialylation on vesicular integrin β1 determined endocytic entry of small extracellular vesicles into recipient cells

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1. scibot 14 Apr 2024
  
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  plasmid_21915
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10983696/
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MUC1-C IS NECESSARY FOR SHP2 ACTIVATION AND BRAF INHIBITOR RESISTANCE IN BRAF(V600E) MUTANT COLORECTAL CANCER

1
1. scibot 14 Apr 2024
  
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  DOI: 10.1016/j.canlet.2023.216116
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10408991/
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Pharmacological induction of chromatin remodeling drives chemosensitization in triple-negative breast cancer

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  DOI: 10.1016/j.xcrm.2024.101504
  
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sciencedirect.com/science/article/pii/S2666379124001733
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Single-cell analyses of metastatic bone marrow in human neuroblastoma reveals microenvironmental remodeling and metastatic signature

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ncbi.nlm.nih.gov/pmc/articles/PMC10972621/
Mar 2024
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Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape

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1. scibot 29 Mar 2024
  
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  DOI: 10.1016/j.molcel.2024.02.032
  
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sciencedirect.com/science/article/pii/S1097276524001758
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DNA fragility at topologically associated domain boundaries is promoted by alternative DNA secondary structure and topoisomerase II activity

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1. scibot 21 Mar 2024
  
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dx.doi.org/10.1093/nar/gkae164
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PRMT5 is an actionable therapeutic target in CDK4/6 inhibitor-resistant ER+/RB-deficient breast cancer

1
1. scibot 17 Mar 2024
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10937713/
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The dePARylase NUDT16 promotes radiation resistance of cancer cells by blocking SETD3 for degradation via reversing its ADP-ribosylation

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1. scibot 16 Mar 2024
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10926213/
Feb 2024
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SLC25A51 decouples the mitochondrial NAD+/NADH ratio to control proliferation of AML cells

3
1. scibot 16 Feb 2024
  
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2. scibot 15 Feb 2024
  
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sciencedirect.com/science/article/pii/S1550413124000135
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NSD1 supports cell growth and regulates autophagy in HPV-negative head and neck squamous cell carcinoma

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1. scibot 15 Feb 2024
  
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  DOI: 10.1038/s41420-024-01842-6
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10861597/
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SOX2 Expression Does Not Guarantee Cancer Stem Cell-like Characteristics in Lung Adenocarcinoma

1
1. scibot 15 Feb 2024
  
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  DOI: 10.3390/cells13030216
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10854781/
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Heat shock factor 1 directly regulates transsulfuration pathway to promote prostate cancer proliferation and survival

1
1. scibot 08 Feb 2024
  
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  DOI: 10.1038/s42003-023-05727-9
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10764307/
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Mechanism-centric regulatory network identifies NME2 and MYC programs as markers of Enzalutamide resistance in CRPC

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1. scibot 08 Feb 2024
  
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  DOI: 10.1038/s41467-024-44686-5
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10774320/
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MUC1-C is a target of salinomycin in inducing ferroptosis of cancer stem cells

1
1. scibot 08 Feb 2024
  
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  Plasmid_21915
  
  DOI: 10.1038/s41420-023-01772-9
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10770371/
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The clarithromycin-binding proteins NIPSNAP1 and 2 regulate cytokine production through mitochondrial quality control

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1. scibot 01 Feb 2024
  
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  DOI: 10.1038/s41598-024-52582-7
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10824736/
Jan 2024
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A Novel Druggable Dual-Specificity tYrosine-Regulated Kinase3/Calmodulin Kinase-like Vesicle-Associated Signaling Module with Therapeutic Implications in Neuroblastoma

1
1. scibot 30 Jan 2024
  
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  DOI: 10.3390/biomedicines12010197
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10813661/
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Coronavirus M Protein Trafficking in Epithelial Cells Utilizes a Myosin Vb Splice Variant and Rab10

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1. scibot 29 Jan 2024
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10814003/
Dec 2023
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Topoisomerase 1 Inhibition in MYC-Driven Cancer Promotes Aberrant R-Loop Accumulation to Induce Synthetic Lethality

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1. scibot 20 Dec 2023
  
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  DOI: 10.1158/0008-5472.CAN-22-2948
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10722143/
Nov 2023
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A combinatorial therapeutic approach to enhance FLT3-ITD AML treatment

1
1. scibot 28 Nov 2023
  
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  plasmid_21915
  
  DOI: 10.1016/j.xcrm.2023.101286
  
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sciencedirect.com/science/article/pii/S2666379123004809
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MUC1-C INTEGRATES AEROBIC GLYCOLYSIS WITH SUPPRESSION OF OXIDATIVE PHOSPHORYLATION IN TRIPLE-NEGATIVE BREAST CANCER STEM CELLS

1
1. scibot 04 Nov 2023
  
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  DOI: 10.1016/j.isci.2023.108168
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10616323/
Oct 2023
52.53.155.43 52.53.155.43

Targeting UBR5 inhibits postsurgical breast cancer lung metastases by inducing CDC73 and p53 mediated apoptosis

1
1. scibot 25 Oct 2023
  
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  plasmid_21915
  
  DOI: 10.1002/ijc.34769
  
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52.53.155.43/dfd537dd38159a379f0051e34a95d721924018c7/Intl Journal of Cancer - 2023 - Yu - Targeting UBR5 inhibits postsurgical breast cancer lung metastases by inducing CDC73-html.html
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TERRA R-loops connect and protect sister telomeres in mitosis

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1. scibot 17 Oct 2023
  
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  DOI: 10.1016/j.celrep.2023.113235
  
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sciencedirect.com/science/article/pii/S2211124723012470
Sep 2023
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Systematic profiling of conditional pathway activation identifies context-dependent synthetic lethalities

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  DOI: 10.1038/s41588-023-01515-7
  
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nature.com/articles/s41588-023-01515-7
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RNF8 ubiquitylation of XRN2 facilitates R-loop resolution and restrains genomic instability in BRCA1 mutant cells

1
1. scibot 22 Sep 2023
  
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  DOI: 10.1093/nar/gkad733
  
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dx.doi.org/10.1093/nar/gkad733
52.53.155.43 52.53.155.43

vdad120-html.html

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  DOI: 10.1093/noajnl/vdad120
  
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52.53.155.43/6d7222f39ce6ff806d6be40a37ce30f7488ce63a/vdad120-html.html
Aug 2023
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The circadian clock protein Cryptochrome 1 is a direct target and feedback regulator of the Hippo pathway

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sciencedirect.com/science/article/pii/S2589004223015262
Jul 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Cancer cell employs a microenvironmental neural signal trans-activating nucleus-mitochondria coordination to acquire stemness

2
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  DOI: 10.1038/s41392-023-01487-4
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10354099/
52.53.155.43 52.53.155.43

cd-22-0411-html.html

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  DOI: 10.1158/2159-8290.CD-22-0411
  
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52.53.155.43/453457acda6208aed297e8061921a5c2d2ddddf2/cd-22-0411-html.html
Jun 2023
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FIRRM/C1orf112 is synthetic lethal with PICH and mediates RAD51 dynamics

1
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  DOI: 10.1016/j.celrep.2023.112668
  
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sciencedirect.com/science/article/pii/S2211124723006794
Mar 2023
academic.oup.com academic.oup.com

Excessive transcription-replication conflicts are a vulnerability of BRCA1-mutant cancers

1
1. scibot 23 Mar 2023
  
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  DOI: 10.1093/nar/gkad172
  
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academic.oup.com/nar/advance-article/doi/10.1093/nar/gkad172/7079642
Feb 2023
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Exercise-activated hepatic autophagy via the FN1-α5β1 integrin pathway drives metabolic benefits of exercise

1
1. scibot 23 Feb 2023
  
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  DOI: 10.1016/j.cmet.2023.01.011
  
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sciencedirect.com/science/article/pii/S1550413123000116
Nov 2022
52.53.155.43 52.53.155.43

Nuclear envelope protein LBR protects the genome from chromosomal instability and tumorigenesis

1
1. scibot 22 Nov 2022
  
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  plasmid_21915
  
  DOI: 10.1093/hmg/ddac235
  
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52.53.155.43/cc79e40c92dade70c5729b9199717becabfd0bfe/ddac235-html.html
Sep 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Original research: Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression

1
1. scibot 22 Sep 2022
  
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  DOI: 10.1136/gutjnl-2021-324994
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9271144/
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NCOA4-mediated ferritinophagy is a pancreatic cancer dependency via maintenance of iron bioavailability for iron-sulfur cluster proteins

1
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Mapping of m6A and Its Regulatory Targets in Prostate Cancer Reveals a METTL3-low Induction of Therapy Resistance

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Fatty acid oxidation protects cancer cells from apoptosis by increasing mitochondrial membrane lipids

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Melanoma-secreted Amyloid Beta Suppresses Neuroinflammation and Promotes Brain Metastasis

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A non-catalytic scaffolding activity of hexokinase 2 contributes to EMT and metastasis

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YAP regulates an SGK1/mTORC1/SREBP-dependent lipogenic program to support proliferation and tissue growth

2
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IL-17B/RB Activation in Pancreatic Stellate Cells Promotes Pancreatic Cancer Metabolism and Growth

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ULK1 phosphorylation of striatin activates protein phosphatase 2A and autophagy

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RSPO2 inhibits BMP signaling to promote self-renewal in acute myeloid leukemia

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BRD9 is a critical regulator of androgen receptor signaling and prostate cancer progression

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Aberrant Activation of a Gastrointestinal Transcriptional Circuit in Prostate Cancer Mediates Castration Resistance

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Tissue of origin dictates GOT1 dependence and confers synthetic lethality to radiotherapy

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The Leukemogenic TCF3-HLF Complex Rewires Enhancers Driving Cellular Identity and Self-Renewal Conferring EP300 Vulnerability

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p63 and SOX2 Dictate Glucose Reliance and Metabolic Vulnerabilities in Squamous Cell Carcinomas

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Plasminogen Activator Inhibitor-1 Promotes the Recruitment and Polarization of Macrophages in Cancer

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Janus Kinase 1 Plays a Critical Role in Mammary Cancer Progression

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cell.com/developmental-cell/abstract/S1534-5807(17)30871-7
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Downregulation of ARID1B, a tumor-suppressor in the WNT subgroup medulloblastoma, activates multiple oncogenic signaling pathways

1
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academic.oup.com/hmg/advance-article/doi/10.1093/hmg/ddab134/6265029
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Depletion of kinesin motor KIF20A to target cell fate control suppresses medulloblastoma tumour growth

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nature.com/articles/s42003-021-02075-4
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NUDT15-mediated hydrolysis limits the efficacy of anti-HCMV drug ganciclovir

1
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Phenotypic plasticity underlies local invasion and distant metastasis in colon cancer

1
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ncbi.nlm.nih.gov/pmc/articles/PMC8192123/
May 2021
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NOX4 links metabolic regulation in pancreatic cancer to endoplasmic reticulum redox vulnerability and dependence on PRDX4

1
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  DOI: 10.1126/sciadv.abf7114
  
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Mitochondria Define Intestinal Stem Cell Differentiation Downstream of a FOXO/Notch Axis

1
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SEED-MEDIATED RNA INTERFERENCE OF ANDROGEN SIGNALING AND SURVIVAL NETWORKS INDUCES CELL DEATH IN PROSTATE CANCER CELLS

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Mar 2021
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Calcium Wave Promotes Cell Extrusion

1
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sciencedirect.com/science/article/pii/S0960982219315945
Feb 2021
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Calcium Wave Promotes Cell Extrusion

1
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  Addgene_21915
  
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MYC Dysregulates Mitosis, Revealing Cancer Vulnerabilities

1
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  DOI: 10.1016/j.celrep.2020.02.041
  
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sciencedirect.com/science/article/pii/S2211124720302023
Sep 2020
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Metabolic Imaging Detects Resistance to PI3Kα Inhibition Mediated by Persistent FOXM1 Expression in ER+ Breast Cancer

1
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Combination Treatment with GSK126 and Pomalidomide Induces B-Cell Differentiation in EZH2 Gain-of-Function Mutant Diffuse Large B-Cell Lymphoma

1
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Tissue of origin dictates GOT1 dependence and confers synthetic lethality to radiotherapy

1
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  RRID:Addgene_21915
  
  DOI: 10.1186/s40170-019-0202-2
  
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journals.plos.org journals.plos.org

Role for the shelterin protein TRF2 in human herpesvirus 6A/B chromosomal integration

1
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Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis

1
1. scibot 06 Sep 2020
  
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  RRID:Addgene_21915
  
  DOI: 10.1016/j.ccell.2019.12.007
  
  Resource: RRID:Addgene_21915
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:Addgene_21915
  
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  RRID:Addgene_21915 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S153561081930577X
www.sciencedirect.com www.sciencedirect.com

The Human Integrator Complex Facilitates Transcriptional Elongation by Endonucleolytic Cleavage of Nascent Transcripts

1
1. scibot 05 Sep 2020
  
  in Public
  
  Tet-pLKO-puro
  
  DOI: 10.1016/j.celrep.2020.107917
  
  Resource: RRID:Addgene_21915
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_21915
  
  Curator comments: Tet-pLKO-puro
  
  What is this?
  
  RRID:Addgene_21915 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S2211124720308986
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Gli2 mediates the development of castration‑resistant prostate cancer

1
1. scibot 05 Sep 2020
  
  in Public
  
  RRID:Addgene_21915
  
  DOI: 10.3892/ijo.2020.5044
  
  Resource: RRID:Addgene_21915
  
  Curator: @evieth
  
  SciCrunch record: RRID:Addgene_21915
  
  What is this?
  
  RRID:Addgene_21915 RRIDCUR:Validated
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ncbi.nlm.nih.gov/pmc/articles/PMC7252461/
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Targeting DGAT1 Ameliorates Glioblastoma by Increasing Fat Catabolism and Oxidative Stress

1
1. scibot 03 Sep 2020
  
  in Public
  
  pLKO-Tet-On vector
  
  DOI: 10.1016/j.cmet.2020.06.002
  
  Resource: RRID:Addgene_21915
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_21915
  
  Curator comments: Tet-pLKO-puro
  
  What is this?
  
  RRID:Addgene_21915 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S155041312030303X
Aug 2020
link.springer.com link.springer.com

Autophagy inhibition impairs the invasion potential of medulloblastoma cells

1
1. scibot 26 Aug 2020
  
  in Public
  
  RRID: Addgene_21915
  
  DOI: 10.1007/s11033-020-05603-3
  
  Resource: RRID:Addgene_21915
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:Addgene_21915
  
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  RRID:Addgene_21915
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link.springer.com/article/10.1007/s11033-020-05603-3
www.sciencedirect.com www.sciencedirect.com

Metabolic Fingerprinting Links Oncogenic PIK3CA with Enhanced Arachidonic Acid-Derived Eicosanoids

1
1. scibot 20 Aug 2020
  
  in Public
  
  Addgene ID: 21915
  
  DOI: 10.1016/j.cell.2020.05.053
  
  Resource: RRID:Addgene_21915
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:Addgene_21915
  
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  RRID:Addgene_21915
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sciencedirect.com/science/article/pii/S0092867420306863
www.sciencedirect.com www.sciencedirect.com

Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis

1
1. scibot 15 Aug 2020
  
  in Public
  
  RRID:Addgene_21915
  
  DOI: 10.1016/j.ccell.2019.12.007
  
  Resource: RRID:Addgene_21915
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:Addgene_21915
  
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  RRID:Addgene_21915
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sciencedirect.com/science/article/pii/S153561081930577X
Jan 2020
www.sciencedirect.com www.sciencedirect.com

A TAZ-AXL-ABL2 Feed-Forward Signaling Axis Promotes Lung Adenocarcinoma Brain Metastasis

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:Addgene_21915
  
  DOI: 10.1016/j.celrep.2019.11.018
  
  Resource: RRID:Addgene_21915
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:Addgene_21915
  
  What is this?
  
  RRID:Addgene_21915 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124719314895
www.sciencedirect.com www.sciencedirect.com

Modeling of Cisplatin-Induced Signaling Dynamics in Triple-Negative Breast Cancer Cells Reveals Mediators of Sensitivity

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:Addgene_21915
  
  DOI: 10.1016/j.celrep.2019.07.070
  
  Resource: RRID:Addgene_21915
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:Addgene_21915
  
  What is this?
  
  RRID:Addgene_21915 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S221112471930974X
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Contribution of synergism between PHF8 and HER2 signalling to breast cancer development and drug resistance

1
1. scibot 13 Jan 2020
  
  in Public
  
  plasmid_21915
  
  DOI: 10.1016/j.ebiom.2019.102612
  
  Resource: RRID:Addgene_21915
  
  Curator: @ethanbadger
  
  SciCrunch record: plasmid_21915
  
  What is this?
  
  RRID:Addgene_21915 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2352396419308278
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:Addgene_21915
  
  DOI: 10.1016/j.celrep.2018.12.043
  
  Resource: RRID:Addgene_21915
  
  Curator: @evieth
  
  SciCrunch record: RRID:Addgene_21915
  
  What is this?
  
  RRID:Addgene_21915 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124718319739
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  plasmid_21915
  
  DOI: 10.1016/j.cmet.2018.12.020
  
  Resource: RRID:Addgene_21915
  
  Curator: @ethanbadger
  
  SciCrunch record: plasmid_21915
  
  What is this?
  
  RRID:Addgene_21915 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1550413118307575
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  Addgene_21915
  
  DOI: 10.1016/j.celrep.2018.12.013
  
  Resource: RRID:Addgene_21915
  
  Curator: @evieth
  
  SciCrunch record: Addgene_21915
  
  What is this?
  
  RRID:Addgene_21915 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124718319247
www.sciencedirect.com www.sciencedirect.com

Tumor-Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer

1
1. scibot 13 Jan 2020
  
  in Public
  
  Addgene_21915
  
  DOI: 10.1016/j.devcel.2017.10.027
  
  Resource: RRID:Addgene_21915
  
  Curator: @Jmenke
  
  SciCrunch record: Addgene_21915
  
  What is this?
  
  RRID:Addgene_21915 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1534580717308717
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:Addgene_21915
  
  DOI: 10.1016/j.ebiom.2019.01.064
  
  Resource: RRID:Addgene_21915
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:Addgene_21915
  
  What is this?
  
  RRID:Addgene_21915 RRIDCUR:Validated
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RRID:Addgene_21915

RRIDCUR:Validated

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scibot

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sciencedirect.com/science/article/pii/S2352396419300702

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