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Feb 2024
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Proline restores mitochondrial function and reverses aging hallmarks in senescent cells

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1. scibot 14 Feb 2024
  
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  plasmid_8453
  
  DOI: 10.1016/j.celrep.2024.113738
  
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sciencedirect.com/science/article/pii/S2211124724000664
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EIF4A3-mediated biogenesis of circSTX6 promotes bladder cancer metastasis and cisplatin resistance

1
1. scibot 13 Feb 2024
  
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  pLKO.1
  
  DOI: 10.1186/s13046-023-02932-6
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10759346/
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The oncogenic role and regulatory mechanism of PGK1 in human non-small cell lung cancer

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1. scibot 13 Feb 2024
  
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  pLKO.1
  
  DOI: 10.1186/s13062-023-00448-9
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10759362/
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Mcam inhibits macrophage-mediated development of mammary gland through non-canonical Wnt signaling

1
1. scibot 13 Feb 2024
  
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  8453
  
  DOI: 10.1038/s41467-023-44338-0
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10761817/
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Pharmaceutical targeting of OTUB2 sensitizes tumors to cytotoxic T cells via degradation of PD-L1

1
1. scibot 13 Feb 2024
  
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  pLKO.1
  
  DOI: 10.1038/s41467-023-44466-7
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10761827/
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SMAD4 inhibits glycolysis in ovarian cancer through PI3K/AKT/HK2 signaling pathway by activating ARHGAP10

1
1. scibot 13 Feb 2024
  
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  pLKO.1
  
  DOI: 10.1002/cnr2.1976
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10849991/
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SMYD3 promotes endometrial cancer through epigenetic regulation of LIG4/XRCC4/XLF complex in non-homologous end joining repair

1
1. scibot 08 Feb 2024
  
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  pLKO.1
  
  DOI: 10.1038/s41389-023-00503-0
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10774296/
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Targeting N-linked Glycosylation for the Therapy of Aggressive Lymphomas

1
1. scibot 06 Feb 2024
  
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  RRID:Addgene_8453
  
  DOI: 10.1158/2159-8290.CD-22-1401
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10524254/
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Cytoplasmic accumulation and plasma membrane association of anillin and Ect2 promote confined migration and invasion

1
1. scibot 05 Feb 2024
  
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  plasmid_8453
  
  DOI: 10.21203/rs.3.rs-3640969/v1
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10802709/
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BRMS1L confers anticancer activity in non-small cell lung cancer by transcriptionally inducing a redox imbalance in the GPX2-ROS pathway

1
1. scibot 05 Feb 2024
  
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  Plasmid_8453
  
  DOI: 10.1016/j.tranon.2023.101870
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10832508/
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c-Fos regulated by TMPO/ERK axis promotes 5-FU resistance via inducing NANOG transcription in colon cancer

1
1. scibot 01 Feb 2024
  
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  8453
  
  DOI: 10.1038/s41419-024-06451-w
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10794174/
Jan 2024
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PICH deficiency limits the progression of MYC-induced B-cell lymphoma

1
1. scibot 30 Jan 2024
  
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  8453
  
  DOI: 10.1038/s41408-024-00979-y
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10803365/
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Caloric restriction leads to druggable LSD1-dependent cancer stem cells expansion

1
1. scibot 30 Jan 2024
  
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  plasmid_8453
  
  DOI: 10.1038/s41467-023-44348-y
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10821871/
dx.doi.org dx.doi.org

Kaposi's sarcoma herpesvirus exploits the DNA damage response to circularize its genome

1
1. scibot 10 Jan 2024
  
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  RRID:Addgene_8453
  
  DOI: 10.1093/nar/gkad1224
  
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dx.doi.org/10.1093/nar/gkad1224
Dec 2023
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Loss of α-1,2-mannosidase MAN1C1 promotes tumorigenesis of intrahepatic cholangiocarcinoma through enhancing CD133-FIP200 interaction

1
1. scibot 20 Dec 2023
  
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  Plasmid_8453
  
  DOI: 10.1016/j.celrep.2023.113588
  
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sciencedirect.com/science/article/pii/S2211124723016005
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Proteomic characterization of the colorectal cancer response to chemoradiation and targeted therapies reveals potential therapeutic strategies

1
1. scibot 17 Dec 2023
  
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  AddgeneCat# 8453
  
  DOI: 10.1016/j.xcrm.2023.101311
  
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sciencedirect.com/science/article/pii/S2666379123005050
link.springer.com link.springer.com

CASC4/GOLM2 drives high grade serous carcinoma anoikis resistance through the recycling of EGFR

1
1. scibot 02 Dec 2023
  
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  RRID:Addgene_8453
  
  DOI: 10.1038/s41417-023-00703-1
  
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link.springer.com/article/10.1038/s41417-023-00703-1
faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com

Lactate produced by alveolar type II cells suppresses inflammatory alveolar macrophages in acute lung injury

1
1. scibot 01 Dec 2023
  
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  RRID:Addgene_8453
  
  DOI: 10.1096/fj.202301722R
  
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faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202301722R
Oct 2023
52.53.155.43 52.53.155.43

Targeting UBR5 inhibits postsurgical breast cancer lung metastases by inducing CDC73 and p53 mediated apoptosis

1
1. scibot 25 Oct 2023
  
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  plasmid_8453
  
  DOI: 10.1002/ijc.34769
  
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52.53.155.43/dfd537dd38159a379f0051e34a95d721924018c7/Intl Journal of Cancer - 2023 - Yu - Targeting UBR5 inhibits postsurgical breast cancer lung metastases by inducing CDC73-html.html
www.nature.com www.nature.com

Pentapeptide PYRAE triggers ER stress-mediated apoptosis of breast cancer cells in mice by targeting RHBDF1-BiP interaction

1
1. scibot 21 Oct 2023
  
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  RRID:Addgene_8453
  
  DOI: 10.1038/s41401-023-01163-x
  
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nature.com/articles/s41401-023-01163-x
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Promyelocytic leukemia protein regulates angiogenesis and epithelial–mesenchymal transition to limit metastasis in MDA‐MB‐231 breast cancer cells

1
1. scibot 07 Oct 2023
  
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  Addgene_8453
  
  DOI: 10.1002/1878-0261.13501
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10552902/
Sep 2023
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TET2-mediated mRNA demethylation regulates leukemia stem cell homing and self-renewal

1
1. scibot 29 Sep 2023
  
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  RRID:Addgene_8453
  
  DOI: 10.1016/j.stem.2023.07.001
  
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sciencedirect.com/science/article/pii/S1934590923002461
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

microRNAs slow translating ribosomes to prevent protein misfolding in eukaryotes

1
1. scibot 20 Sep 2023
  
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  Addgene_8453
  
  DOI: 10.15252/embj.2022112469
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10505912/
www.biorxiv.org www.biorxiv.org

A Meta-Atlas of the Developing Human Cortex Identifies Modules Driving Cell Subtype Specification

1
1. scibot 19 Sep 2023
  
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  Addgene_8453
  
  DOI: 10.1101/2023.09.12.557406
  
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biorxiv.org/content/10.1101/2023.09.12.557406v1
52.53.155.43 52.53.155.43

British J Pharmacology - 2023 - Yin-html.html

2
1. scibot 16 Sep 2023
  
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  plasmid_8453
  
  DOI: 10.1111/bph.16245
  
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2. scibot 16 Sep 2023
  
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  plasmid_8453
  
  DOI: 10.1111/bph.16245
  
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52.53.155.43/3f4c3b7a8c80fd686d3f27ef9d97ee6662a4385e/British J Pharmacology - 2023 - Yin-html.html
www.sciencedirect.com www.sciencedirect.com

CD44 correlates with longevity and enhances basal ATF6 activity and ER stress resistance

1
1. scibot 16 Sep 2023
  
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  Addgene_8453
  
  DOI: 10.1016/j.celrep.2023.113130
  
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sciencedirect.com/science/article/pii/S2211124723011427
link.springer.com link.springer.com

The Endolysosomal Transporter DMT1 is Required for Morphine Regulation of Neuronal Ferritin Heavy Chain

1
1. scibot 07 Sep 2023
  
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  RRID:Addgene_8453
  
  DOI: 10.1007/s11481-023-10082-x
  
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link.springer.com/article/10.1007/s11481-023-10082-x
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Crizotinib has Preclinical Efficacy in Philadelphia-negative Myeloproliferative Neoplasms

1
1. scibot 07 Sep 2023
  
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  RRID:Addgene_8453
  
  DOI: 10.1158/1078-0432.CCR-22-1763
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9992133/
Aug 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The circadian clock circuitry modulates leukemia initiating cell activity in T-cell acute lymphoblastic leukemia

1
1. scibot 31 Aug 2023
  
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  Addgene_8453
  
  DOI: 10.1186/s13046-023-02799-7
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10464343/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Porcine reproductive and respiratory syndrome virus upregulates SMPDL3B to promote viral replication by modulating lipid metabolism

1
1. scibot 19 Aug 2023
  
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  addgene_8453
  
  DOI: 10.1016/j.isci.2023.107450
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10424083/
52.53.155.43 52.53.155.43

MOF-mediated acetylation of SIRT6 disrupts SIRT6-FOXA2 interaction and represses SIRT6 tumor-suppressive function by upregulating ZEB2 in NSCLC

2
1. scibot 17 Aug 2023
  
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  plasmid_8453
  
  DOI: 10.1016/j.celrep.2023.112939
  
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2. scibot 11 Aug 2023
  
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  plasmid_8453
  
  DOI: 10.1016/j.celrep.2023.112939
  
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52.53.155.43/bd09065dee8428d4c17fca329effba1c6cc59b0c/PIIS2211124723009506-html.html
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

β-Catenin Drives Butyrophilin-like Molecule Loss and γδ T-cell Exclusion in Colon Cancer

1
1. scibot 05 Aug 2023
  
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  Addgene_8453
  
  DOI: 10.1158/2326-6066.CIR-22-0644
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10398359/
Jul 2023
52.53.155.43 52.53.155.43

rational-design-and-development-of-selective-brd7-bromodomain-inhibitors-and-their-activity-in-prostate-cancer-html.html

1
1. scibot 26 Jul 2023
  
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  plasmid_8453
  
  DOI: 10.26434/chemrxiv-2023-phgwf
  
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52.53.155.43/fbc444166f400a01dc32894063d12537e1e236f5/rational-design-and-development-of-selective-brd7-bromodomain-inhibitors-and-their-activity-in-prostate-cancer-html.html
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Cancer cell employs a microenvironmental neural signal trans-activating nucleus-mitochondria coordination to acquire stemness

2
1. scibot 21 Jul 2023
  
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  RRID:Addgene_8453
  
  DOI: 10.1038/s41392-023-01487-4
  
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2. scibot 21 Jul 2023
  
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  DOI: 10.1038/s41392-023-01487-4
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10354099/
Jun 2023
www.nature.com www.nature.com

The effect of inhibition of receptor tyrosine kinase AXL on DNA damage response in ovarian cancer

1
1. scibot 24 Jun 2023
  
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  RRID:Addgene_8453
  
  DOI: 10.1038/s42003-023-05045-0
  
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Targeted MDM2 degradation reveals a new vulnerability for p53 inactivated triple negative breast cancer

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Endogenous PP2A inhibitor CIP2A degradation by chaperone-mediated autophagy contributes to the antitumor effect of mitochondrial complex I inhibition

1
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Enhanced glutaminolysis drives hypoxia-induced chemoresistance in pancreatic cancer

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KLHL7 promotes hepatocellular carcinoma progression and molecular therapy resistance by degrading RASA2

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Modeling human ectopic pregnancies with trophoblast and vascular organoids

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Glucocerebrosidase is imported into mitochondria and preserves complex I integrity and energy metabolism

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PYHIN protein IFI207 regulates cytokine transcription and IRF7 and contributes to the establishment of K. pneumoniae infection

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Excessive transcription-replication conflicts are a vulnerability of BRCA1-mutant cancers

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943-html.html

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Combined Inhibition of Smoothened and the DNA Damage Checkpoint WEE1 Exerts Antitumor Activity in Cholangiocarcinoma

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Feb 2023
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Krüppel-like factor 9 (KLF9) links hormone dysregulation and circadian disruption to breast cancer pathogenesis

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The mitochondrial chaperone TRAP-1 regulates the glutamine metabolism in tumor cells

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Numb/Parkin-directed mitochondrial fitness governs cancer cell fate via metabolic regulation of histone lactylation

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Decoding m6A RNA methylome identifies PRMT6-regulated lipid transport promoting AML stem cell maintenance

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SAYSD1 senses UFMylated ribosome to safeguard co-translational protein translocation at the endoplasmic reticulum

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TRIM28 secures skeletal stem cell fate during skeletogenesis by silencing neural gene expression and repressing GREM1/AKT/mTOR signaling axis

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Loss of VOPP1 Contributes to BET Inhibitor Acquired Resistance in Non–Small Cell Lung Cancer Cells

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Inhibition of interaction between ROCK1 and Rubicon restores autophagy in endothelial cells and attenuates brain injury after prolonged ischemia

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Enhancing PD-L1 Degradation by ITCH during MAPK Inhibitor Therapy Suppresses Acquired Resistance

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METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism

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Hypoxia activated HGF expression in pancreatic stellate cells confers resistance of pancreatic cancer cells to EGFR inhibition

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Bortezomib inhibits ZIKV/DENV by interfering with viral polyprotein cleavage via the ERAD pathway

1
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Nucleoplasmic lamin C rapidly accumulates at sites of nuclear envelope rupture with BAF and cGAS

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Oct 2022
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CircIPO7 Promotes Nasopharyngeal Carcinoma Metastasis and Cisplatin Chemoresistance by Facilitating YBX1 Nuclear Localization

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Sep 2022
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TGFBR3 supports anoikis through suppressing ATF4 signaling

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Meteorin links the bone marrow hypoxic state to hematopoietic stem/progenitor cell mobilization

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TRIM56 impairs HBV infection and replication by inhibiting HBV core promoter activity

1
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Proteomic mapping and targeting of mitotic pericentriolar material in tumors bearing centrosome amplification

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Jul 2022
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HMCES modulates the transcriptional regulation of nodal/activin and BMP signaling in mESCs

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Pharmacotherapy alleviates pathological changes in human direct reprogrammed neuronal cell model of myotonic dystrophy type 1

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EPH receptor tyrosine kinases phosphorylate the PAR-3 scaffold protein to modulate downstream signaling networks

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Jun 2022
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A pro-metastatic tRNA fragment drives Nucleolin oligomerization and stabilization of its bound metabolic mRNAs

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May 2022
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  Addgene_84530
  
  DOI: 10.21203/rs.3.rs-658360/v1
  
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Aspartate metabolism in endothelial cells activates the mTORC1 pathway to initiate translation during angiogenesis

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Concurrent Inhibition of ERK and Farnesyltransferase Suppresses the Growth of HRAS Mutant Head and Neck Squamous Cell Carcinoma

1
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Apr 2022
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Functional genetic screen identifies ITPR3/calcium/RELB axis as a driver of colorectal cancer metastatic liver colonization

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Filamentous GLS1 promotes ROS-induced apoptosis upon glutamine deprivation via insufficient asparagine synthesis

1
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  RRID:Addgene_8453
  
  DOI: 10.1016/j.molcel.2022.03.016
  
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MLL5 is involved in retinal photoreceptor maturation through facilitating CRX-mediated photoreceptor gene transactivation

1
1. scibot 01 Apr 2022
  
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  Addgene_8453
  
  DOI: 10.1016/j.isci.2022.104058
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8961232/
Mar 2022
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Positive feedback regulation of microglial glucose metabolism by histone H4 lysine 12 lactylation in Alzheimer’s disease

1
1. scibot 27 Mar 2022
  
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  AddgeneCat# 8453
  
  DOI: 10.1016/j.cmet.2022.02.013
  
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Jan 2022
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Occludin is a target of Src kinase and promotes lipid secretion by binding to BTN1a1 and XOR

1
1. scibot 22 Jan 2022
  
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  Addgene_8453
  
  DOI: 10.1371/journal.pbio.3001518
  
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Biphasic regulation of glutamine consumption by WNT during osteoblast differentiation

1
1. scibot 12 Jan 2022
  
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  RRID:Addgene_8453
  
  DOI: 10.1242/jcs.251645
  
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Restriction of extracellular lipids renders pancreatic cancer dependent on autophagy

1
1. scibot 11 Jan 2022
  
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  RRID:Addgene_8453
  
  DOI: 10.1186/s13046-021-02231-y
  
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link.springer.com/article/10.1186/s13046-021-02231-y
Dec 2021
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Characterization of Type 1 Angiotensin II Receptor Activation Induced Dual-Specificity MAPK Phosphatase Gene Expression Changes in Rat Vascular Smooth Muscle Cells

1
1. scibot 21 Dec 2021
  
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  RRID:Addgene_8453
  
  DOI: 10.3390/cells10123538
  
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A mechanistic basis for the malignant progression of salivary gland tumors

1
1. scibot 08 Dec 2021
  
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  Addgene_8453
  
  DOI: 10.1016/j.isci.2021.103508
  
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sciencedirect.com/science/article/pii/S2589004221014796
Nov 2021
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TM4SF5-dependent crosstalk between hepatocytes and macrophages to reprogram the inflammatory environment

1
1. scibot 17 Nov 2021
  
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  RRID:Addgene_8453
  
  DOI: 10.1016/j.celrep.2021.110018
  
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Fetal growth restriction impairs hippocampal neurogenesis and cognition via Tet1 in offspring

2
1. scibot 17 Nov 2021
  
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  RRID:AB_8453
  
  DOI: 10.1016/j.celrep.2021.109912
  
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2. scibot 03 Nov 2021
  
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  plasmid_8453
  
  DOI: 10.1016/j.celrep.2021.109912
  
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Oct 2021
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Differential m6A RNA landscapes across hematopoiesis reveal a role for IGF2BP2 in preserving hematopoietic stem cell function

1
1. scibot 22 Oct 2021
  
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  Addgene_8453
  
  DOI: 10.1016/j.stem.2021.09.014
  
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Tyrosine Phosphorylation of DEPTOR Functions as a Molecular Switch to Activate mTOR Signaling

1
1. scibot 14 Oct 2021
  
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  RRID:Addgene_8453
  
  DOI: 10.1016/j.jbc.2021.101291
  
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Functional differences between Hsp105/110 family proteins in cell proliferation, cell division, and drug sensitivity

1
1. scibot 08 Oct 2021
  
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  plasmid_8453
  
  DOI: 10.1002/jcb.30158
  
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onlinelibrary.wiley.com/doi/10.1002/jcb.30158
Sep 2021
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The thermogenic activity of adjacent adipocytes fuels the progression of ccRCC and compromises anti-tumor therapeutic efficacy

1
1. scibot 11 Sep 2021
  
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  Cat# 8453
  
  DOI: 10.1016/j.cmet.2021.08.012
  
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Cilium induction triggers differentiation of glioma stem cells

1
1. scibot 08 Sep 2021
  
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  RRID:Addgene_8453
  
  DOI: 10.1016/j.celrep.2021.109656
  
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HBO1-MLL interaction promotes AF4/ENL/P-TEFb-mediated leukemogenesis

2
1. scibot 04 Sep 2021
  
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  Addgene_8453
  
  DOI: 10.7554/eLife.65872
  
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  RRID:Addgene_84530
  
  DOI: 10.7554/eLife.65872
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8387021/
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The cAMP effector PKA mediates Moody GPCR signaling in Drosophila blood–brain barrier formation and maturation

1
1. scibot 04 Sep 2021
  
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  RRID:AB_2568479RRID:AB_2568479
  
  DOI: 10.7554/eLife.68275
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8390003/
Aug 2021
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BRD9 is a critical regulator of androgen receptor signaling and prostate cancer progression

1
1. scibot 17 Aug 2021
  
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  RRID:Addgene_8453
  
  DOI: 10.1158/0008-5472.CAN-20-1417
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8026650/
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PHB Associates with the HIRA Complex to Control an Epigenetic-Metabolic Circuit in Human ESCs

1
1. scibot 09 Aug 2021
  
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  plasmid_8453
  
  DOI: 10.1016/j.stem.2016.11.002
  
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GPR120 signaling controls amyloid-β degrading activity of matrix metalloproteinases

1
1. scibot 07 Aug 2021
  
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  RRID:Addgene_8453
  
  DOI: 10.1523/JNEUROSCI.2595-20.2021
  
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jneurosci.org/content/41/28/6173
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Aberrant Activation of a Gastrointestinal Transcriptional Circuit in Prostate Cancer Mediates Castration Resistance

1
1. scibot 06 Aug 2021
  
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  plasmid_8453
  
  DOI: 10.1016/j.ccell.2017.10.008
  
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sciencedirect.com/science/article/pii/S1535610817304610
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METTL1-mediated m7G modification of Arg-TCT tRNA drives oncogenic transformation

1
1. scibot 05 Aug 2021
  
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  Cat# 8453
  
  DOI: 10.1016/j.molcel.2021.06.031
  
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sciencedirect.com/science/article/pii/S1097276521005426
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14–3-3ζ inhibits heme oxygenase-1 (HO-1) degradation and promotes hepatocellular carcinoma proliferation: involvement of STAT3 signaling

1
1. scibot 05 Aug 2021
  
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  plasmid_8453
  
  DOI: 10.1186/s13046-018-1007-9
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6319010/
Jul 2021
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DEAD-Box Helicase 18 Counteracts PRC2 to Safeguard Ribosomal DNA in Pluripotency Regulation

1
1. scibot 30 Jul 2021
  
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  Addgene, # 8453
  
  DOI: 10.1016/j.celrep.2019.12.021
  
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sciencedirect.com/science/article/pii/S2211124719316717
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Modeling of Cisplatin-Induced Signaling Dynamics in Triple-Negative Breast Cancer Cells Reveals Mediators of Sensitivity

1
1. scibot 29 Jul 2021
  
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  RRID:Addgene_8453
  
  DOI: 10.1016/j.celrep.2019.07.070
  
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Depletion of the Transcriptional Coactivator Amplified in Breast Cancer 1 (AIB1) Uncovers Functionally Distinct Subpopulations in Triple-Negative Breast Cancer

1
1. scibot 29 Jul 2021
  
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  #8453; Addgene
  
  DOI: 10.1016/j.neo.2019.07.001
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6706655/
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Untitled document

1
1. scibot 29 Jul 2021
  
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  plasmid_8453
  
  DOI: 10.1038/s41421-018-0068-4
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6312541/
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IFI16 Targets the Transcription Factor Sp1 to Suppress HIV-1 Transcription and Latency Reactivation

1
1. scibot 28 Jul 2021
  
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  Plasmid: pLKO.1 puro
  
  DOI: 10.1016/j.chom.2019.05.002
  
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sciencedirect.com/science/article/pii/S1931312819302471
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Untitled document

1
1. scibot 28 Jul 2021
  
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  plasmid_8453
  
  DOI: 10.1016/j.ccell.2017.10.008
  
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cell.com/cancer-cell/abstract/S1535-6108(17)30461-0
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Untitled document

1
1. scibot 27 Jul 2021
  
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  Plasmid_8453
  
  DOI: 10.1016/j.immuni.2018.10.011
  
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sciencedirect.com/science/article/pii/S107476131830476X
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Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity

1
1. scibot 22 Jul 2021
  
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  RRID:Addgene_8453
  
  DOI: 10.1016/j.ccell.2021.06.016
  
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sciencedirect.com/science/article/pii/S153561082100338X
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SIRT4 is an early regulator of branched-chain amino acid catabolism that promotes adipogenesis

1
1. scibot 14 Jul 2021
  
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  Plasmid_8453
  
  DOI: 10.1016/j.celrep.2021.109345
  
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sciencedirect.com/science/article/pii/S221112472100721X
Jun 2021
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Revealing molecular pathways for cancer cell fitness through a genetic screen of the cancer translatome

1
1. scibot 30 Jun 2021
  
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  Addgene #8453
  
  DOI: 10.1016/j.celrep.2021.109321
  
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sciencedirect.com/science/article/pii/S2211124721006975
faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com

Surface AMP deaminase 2 as a novel regulator modifying extracellular adenine nucleotide metabolism

1
1. scibot 26 Jun 2021
  
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  RRID:Addgene_8453
  
  DOI: 10.1096/fj.202002658RR
  
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faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202002658RR
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Evaluation of glycolytic rates in human hematopoietic stem/progenitor cells after target gene depletion

1
1. scibot 15 Jun 2021
  
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  plasmid_8453
  
  DOI: 10.1016/j.xpro.2021.100603
  
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sciencedirect.com/science/article/pii/S2666166721003105
May 2021
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miR-637 Prevents Glioblastoma Progression by Interrupting ZEB2/WNT/β-catenin Cascades

1
1. scibot 29 May 2021
  
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  RRID:Addgene_8453
  
  DOI: 10.1007/s10571-021-01107-1
  
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link.springer.com/article/10.1007/s10571-021-01107-1
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Adhesion-mediated mechanosignaling forces mitohormesis

1
1. scibot 21 May 2021
  
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  Addgene_8453
  
  DOI: 10.1016/j.cmet.2021.04.017
  
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sciencedirect.com/science/article/pii/S1550413121001832
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The oncogenic E3 ligase TRIP12 suppresses epithelial–mesenchymal transition (EMT) and mesenchymal traits through ZEB1/2

1
1. scibot 12 May 2021
  
  in Public
  
  RRID:Addgene_8453
  
  DOI: 10.1038/s41420-021-00479-z
  
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nature.com/articles/s41420-021-00479-z
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Persistent NF-κB activation in muscle stem cells induces proliferation-independent telomere shortening

1
1. scibot 12 May 2021
  
  in Public
  
  RRID:Addgene_8453
  
  DOI: 10.1016/j.celrep.2021.109098
  
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sciencedirect.com/science/article/pii/S2211124721004320
clincancerres.aacrjournals.org clincancerres.aacrjournals.org

YAP1 Mediates Trametinib Resistance in Head and Neck Squamous Cell Carcinomas

1
1. scibot 10 May 2021
  
  in Public
  
  RRID:Addgene_8453
  
  DOI: 10.1158/1078-0432.CCR-19-4179
  
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clincancerres.aacrjournals.org/content/27/8/2326
Apr 2021
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Mutant p53 suppresses innate immune signaling to promote tumorigenesis

1
1. scibot 22 Apr 2021
  
  in Public
  
  Addgene_8453
  
  DOI: 10.1016/j.ccell.2021.01.003
  
  Resource: RRID:Addgene_8453
  
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  RRIDCUR:Validated RRID:Addgene_8453
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sciencedirect.com/science/article/pii/S1535610821000416
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Elevated CXorf67 Expression in PFA Ependymomas Suppresses DNA Repair and Sensitizes to PARP Inhibitors

1
1. scibot 22 Apr 2021
  
  in Public
  
  RRID:Addgene_8453
  
  DOI: 10.1016/j.ccell.2020.10.009
  
  Resource: RRID:Addgene_8453
  
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  RRIDCUR:Validated RRID:Addgene_8453
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ncbi.nlm.nih.gov/pmc/articles/PMC8455074/
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Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion

1
1. scibot 17 Apr 2021
  
  in Public
  
  plasmid_8453
  
  DOI: 10.1016/j.ccell.2020.04.017
  
  Resource: RRID:Addgene_8453
  
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sciencedirect.com/science/article/pii/S1535610820302166
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Increased p53 signaling impairs neural differentiation in HUWE1-promoted intellectual disabilities

1
1. scibot 09 Apr 2021
  
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  8453
  
  DOI: 10.1016/j.xcrm.2021.100240
  
  Resource: RRID:Addgene_8453
  
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  RRID:Addgene_8453 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S2666379121000562
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RNA demethylation by FTO stabilizes the FOXJ1 mRNA for proper motile ciliogenesis

1
1. scibot 02 Apr 2021
  
  in Public
  
  addgene_8453
  
  DOI: 10.1016/j.devcel.2021.03.006
  
  Resource: RRID:Addgene_8453
  
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  RRID:Addgene_8453 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1534580721002033
Mar 2021
faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com

Targeting alveolar‐specific succinate dehydrogenase A attenuates pulmonary inflammation during acute lung injury

1
1. scibot 13 Mar 2021
  
  in Public
  
  RRID:Addgene_8453
  
  DOI: 10.1096/fj.202002778R
  
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faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.202002778R
Feb 2021
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R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m6A/PFKP/LDHB axis

1
1. scibot 28 Feb 2021
  
  in Public
  
  plasmid_8453
  
  DOI: 10.1016/j.molcel.2020.12.026
  
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sciencedirect.com/science/article/pii/S1097276520309473
Oct 2020
www.sciencedirect.com www.sciencedirect.com

PAI-1-Dependent Inactivation of SMAD4-Modulated Junction and Adhesion Complex in Obese Endometrial Cancer

1
1. scibot 21 Oct 2020
  
  in Public
  
  pLKO.1 puro
  
  DOI: 10.1016/j.celrep.2020.108253
  
  Resource: RRID:Addgene_8453
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_8453
  
  Curator comments: pLKO.1 puro
  
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  RRID:Addgene_8453 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S2211124720312420
Sep 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PCK1 and DHODH drive colorectal cancer liver metastatic colonization and hypoxic growth by promoting nucleotide synthesis

1
1. scibot 26 Sep 2020
  
  in Public
  
  RRID:Addgene_8453
  
  DOI: 10.7554/eLife.52135
  
  Resource: RRID:Addgene_8453
  
  Curator: @evieth
  
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  RRID:Addgene_8453 RRIDCUR:Validated
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ncbi.nlm.nih.gov/pmc/articles/PMC7299340/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Mitochondrial Membrane Potential Regulates Nuclear Gene Expression in Macrophages Exposed to Prostaglandin E2

1
1. scibot 26 Sep 2020
  
  in Public
  
  Plasmid_8453
  
  DOI: 10.1016/j.immuni.2018.10.011
  
  Resource: RRID:Addgene_8453
  
  Curator: @evieth
  
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  RRID:Addgene_8453 RRIDCUR:Validated
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ncbi.nlm.nih.gov/pmc/articles/PMC7271981/
academic.oup.com academic.oup.com

Differential glucocorticoid-dependent regulation and function of the ERRFI1 gene in triple-negative breast cancer

1
1. scibot 23 Sep 2020
  
  in Public
  
  RRID:Addgene_8453
  
  DOI: 10.1210/endocr/bqaa082
  
  Resource: RRID:Addgene_8453
  
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  RRID:Addgene_8453 RRIDCUR:Validated
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academic.oup.com/endo/article/161/7/bqaa082/5841101
www.nature.com www.nature.com

The ACSL3-LPIAT1 signaling drives prostaglandin synthesis in non-small cell lung cancer

1
1. scibot 17 Sep 2020
  
  in Public
  
  RRID:Addgene_8453
  
  DOI: 10.1038/s41388-020-1196-5
  
  Resource: RRID:Addgene_8453
  
  Curator: @evieth
  
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  RRIDCUR:Validated RRID:Addgene_8453
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nature.com/articles/s41388-020-1196-5
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

BMAL1 coordinates energy metabolism and differentiation of pluripotent stem cells

1
1. scibot 15 Sep 2020
  
  in Public
  
  plasmid_8453
  
  DOI: 10.26508/lsa.201900534
  
  Resource: RRID:Addgene_8453
  
  Curator: @evieth
  
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  RRID:Addgene_8453 RRIDCUR:Validated
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ncbi.nlm.nih.gov/pmc/articles/PMC7156282/
www.sciencedirect.com www.sciencedirect.com

YTHDF2/3 Are Required for Somatic Reprogramming through Different RNA Deadenylation Pathways

1
1. scibot 10 Sep 2020
  
  in Public
  
  PLKO.1-puro
  
  DOI: 10.1016/j.celrep.2020.108120
  
  Resource: RRID:Addgene_8453
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_8453
  
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  RRID:Addgene_8453 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S2211124720311098
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Endolysosomal Targeting of Mitochondria Is Integral to BAX-Mediated Mitochondrial Permeabilization during Apoptosis Signaling

1
1. scibot 07 Sep 2020
  
  in Public
  
  RRID:Addgene_8453
  
  DOI: 10.1016/j.devcel.2020.05.014
  
  Resource: RRID:Addgene_8453
  
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  RRID:Addgene_8453 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1534580720304032
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RNA Demethylase ALKBH5 Selectively Promotes Tumorigenesis and Cancer Stem Cell Self-Renewal in Acute Myeloid Leukemia

1
1. scibot 07 Sep 2020
  
  in Public
  
  RRID:Addgene_8453
  
  DOI: 10.1016/j.stem.2020.04.009
  
  Resource: RRID:Addgene_8453
  
  Curator: @ethanbadger
  
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  RRID:Addgene_8453 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S193459092030148X
rupress.org rupress.org

Genetic manipulation of LKB1 elicits lethal metastatic prostate cancer

1
1. scibot 06 Sep 2020
  
  in Public
  
  RRID:Addgene_8453
  
  DOI: 10.1084/jem.20191787
  
  Resource: RRID:Addgene_8453
  
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  RRID:Addgene_8453 RRIDCUR:Validated
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rupress.org/jem/article/217/6/e20191787/151590/Genetic-manipulation-of-LKB1-elicits-lethal
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Leukemogenic Chromatin Alterations Promote AML Leukemia Stem Cells via a KDM4C-ALKBH5-AXL Signaling Axis

1
1. scibot 03 Sep 2020
  
  in Public
  
  Addgene Cat#8453
  
  DOI: 10.1016/j.stem.2020.04.001
  
  Resource: RRID:Addgene_8453
  
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sciencedirect.com/science/article/pii/S1934590920301405
www.sciencedirect.com www.sciencedirect.com

Acetylation of UHRF1 Regulates Hemi-methylated DNA Binding and Maintenance of Genome-wide DNA Methylation

1
1. scibot 03 Sep 2020
  
  in Public
  
  pLKO.1-puro
  
  DOI: 10.1016/j.celrep.2020.107958
  
  Resource: RRID:Addgene_8453
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_8453
  
  Curator comments: pLKO.1 puro
  
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  RRID:Addgene_8453 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S2211124720309396
link.springer.com link.springer.com

YAP1 regulates chondrogenic differentiation of ATDC5 promoted by temporary TNF-α stimulation through AMPK signaling pathway

1
1. scibot 03 Sep 2020
  
  in Public
  
  RRID:Addgene_8453
  
  DOI: 10.1007/s11010-020-03846-z
  
  Resource: RRID:Addgene_8453
  
  Curator: @Naa003
  
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  RRIDCUR:Validated RRID:Addgene_8453
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link.springer.com/article/10.1007/s11010-020-03846-z
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  Plasmid_8453
  
  DOI: 10.1016/j.celrep.2018.12.100
  
  Resource: RRID:Addgene_8453
  
  Curator: @evieth
  
  SciCrunch record: Plasmid_8453
  
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  RRID:Addgene_8453 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124718320758
www.sciencedirect.com www.sciencedirect.com

Transmembrane 4 L Six Family Member 5 Senses Arginine for mTORC1 Signaling

1
1. scibot 13 Jan 2020
  
  in Public
  
  Addgene_8453
  
  DOI: 10.1016/j.cmet.2019.03.005
  
  Resource: RRID:Addgene_8453
  
  Curator: @ethanbadger
  
  SciCrunch record: Addgene_8453
  
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  RRID:Addgene_8453 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1550413119301330
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 12 Jan 2020
  
  in Public
  
  RRID:Addgene_8453
  
  DOI: 10.1016/j.celrep.2019.02.102
  
  Resource: RRID:Addgene_8453
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:Addgene_8453
  
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  RRID:Addgene_8453 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124719302888

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