414 Matching Annotations
  1. Aug 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EZH2 represses mesenchymal genes and upholds the epithelial state of breast carcinoma cells
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11341823/
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor-derived GLI1 promotes remodeling of the immune tumor microenvironment in melanoma
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11295348/
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Centenarian hippocampus displays high levels of astrocytic metallothioneins
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11320342/
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Elimination of damaged mitochondria during UVB‐induced senescence is orchestrated by NIX‐dependent mitophagy
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11320349/
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tight Junction Component Occludin Binds to FIP5 to Regulate Endosome Trafficking and Mitotic Spindle Function
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11321699/
  7. www.sciencedirect.com www.sciencedirect.com
    Dopaminylation of endothelial TPI1 suppresses ferroptotic angiocrine signals to promote lung regeneration over fibrosis
    1
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    sciencedirect.com/science/article/pii/S1550413124002808
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TERT upstream promoter methylation regulates TERT expression and acts as a therapeutic target in TERT promoter mutation-negative thyroid cancer
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11297792/
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Blocking methionine catabolism induces senescence and confers vulnerability to GSK3 inhibition in liver cancer
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11277537/
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 nucleocapsid protein promotes self-deacetylation by inducing HDAC6 to facilitate viral replication
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11321199/
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multi-omics integration identifies cell-state-specific repression by PBRM1-PIAS1 cooperation
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10794847/
  12. Jul 2024
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MUC1-C Dependence for the Progression of Pancreatic Neuroendocrine Tumors Identifies a Druggable Target for the Treatment of This Rare Cancer
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11274714/
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LSM12-EPAC1 defines a neuroprotective pathway that sustains the nucleocytoplasmic RAN gradient
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC7757817/
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metformin synergizes with gilteritinib in treating FLT3-mutated leukemia via targeting PLK1 signaling
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11293342/
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNA-guided RNA silencing by an Asgard archaeal Argonaute
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11217426/
  17. Jun 2024
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Improvement of histone deacetylase inhibitor efficacy by SN38 through TWIST1 suppression in synovial sarcoma
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11212284/
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lovastatin-Induced Mitochondrial Oxidative Stress Leads to the Release of mtDNA to Promote Apoptosis by Activating cGAS-STING Pathway in Human Colorectal Cancer Cells
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11200898/
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRMT5-mediated methylation of STAT3 is required for lung cancer stem cell maintenance and tumour growth
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11101626/
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The balance between antiviral and antibacterial responses during M. tuberculosis infection is regulated by the ubiquitin ligase CBL
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11118416/
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Caspase-4 promotes metastasis and interferon-γ-induced pyroptosis in lung adenocarcinoma
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11161495/
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lysine acetyltransferase 14 mediates TGF-β-induced fibrosis in ovarian endometrioma via co-operation with serum response factor
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11167823/
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LncRNA IRAIN overcomes imatinib resistance in chronic myeloid leukemia via NF-κB/CD44 pathway inhibition
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11112338/
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modulation of Paracellular Permeability in SARS-CoV-2 Blood-to-Brain Transcytosis
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11126142/
  26. www.biorxiv.org www.biorxiv.org
    The tumor-maintaining function of UTX/KDM6A in DNA replication and the PARP1-dependent repair pathway
    1
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    biorxiv.org/content/10.1101/2024.05.31.596824v1
  27. www.sciencedirect.com www.sciencedirect.com
    Cancer-specific epigenome identifies oncogenic hijacking by nuclear factor I family proteins for medulloblastoma progression
    3
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    sciencedirect.com/science/article/pii/S1534580724003307
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Microbiota enterotoxigenic Bacteroides fragilis-secreted BFT-1 promotes breast cancer cell stemness and chemoresistance through its functional receptor NOD1
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11131025/
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dynamic movement of the Golgi unit and its glycosylation enzyme zones
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11130159/
  30. May 2024
  31. www.biorxiv.org www.biorxiv.org
    Spatiotemporal proteomics reveals the biosynthetic lysosomal membrane protein interactome in neurons
    1
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    biorxiv.org/content/10.1101/2024.05.16.594502v1
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deficiency of UCHL1 results in insufficient decidualization accompanied by impaired dNK modulation and eventually miscarriage
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11103838/
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    METTL8 links mt-tRNA m3C modification to the HIF1α/RTK/Akt axis to sustain GBM stemness and tumorigenicity
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11093979/
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hypoxia-induced NOS1 as a therapeutic target in hypercholesterolemia-related colorectal cancer
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11100240/
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mecp2 fine-tunes quiescence exit by targeting nuclear receptors
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11095939/
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CYB561 supports the neuroendocrine phenotype in castration-resistant prostate cancer
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11090301/
  37. www.sciencedirect.com www.sciencedirect.com
    USP7 promotes IgA class switching through stabilizing RUNX3 for germline transcription activation
    1
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    sciencedirect.com/science/article/pii/S2211124724005229
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DDX18 Facilitates the Tumorigenesis of Lung Adenocarcinoma by Promoting Cell Cycle Progression through the Upregulation of CDK4
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11084921/
  39. 52.53.155.43 52.53.155.43
    TERC promotes non-small cell lung cancer progression by facilitating the nuclear localization of TERT
    1
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    52.53.155.43/761c70660e3a03a822484173742c13c4c44cc6bf/PIIS2589004224010915-html.html
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Role of proteoglycan synthesis genes in osteosarcoma stem cells
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11058990/
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRRX1-TOP2A interaction is a malignancy-promoting factor in human malignant peripheral nerve sheath tumours
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11058259/
  42. Apr 2024
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combined SNPs sequencing and allele specific proteomics capture reveal functional causality underpinning the 2p25 prostate cancer susceptibility locus
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11030545/
  44. www.pnas.org www.pnas.org
    NOVA1 acts as an oncogenic RNA-binding protein to regulate cholesterol homeostasis in human glioblastoma cells
    1
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    pnas.org/doi/abs/10.1073/pnas.2314695121
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation by the RNA-binding protein Unkempt at its effector interface
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11009413/
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An EBV-related CD4 TCR immunotherapy inhibits tumor growth in an HLA-DP5+ nasopharyngeal cancer mouse model
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11014665/
  47. www.embopress.org www.embopress.org
    PRODH safeguards human naive pluripotency by limiting mitochondrial oxidative phosphorylation and reactive oxygen species production
    1
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    embopress.org/doi/full/10.1038/s44319-024-00110-z
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lysophosphatidic acid down-regulates human RIPK4 mRNA in keratinocyte- derived cell lines
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11023271/
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Revealing the grammar of small RNA secretion using interpretable machine learning
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11019361/
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The dimeric deubiquitinase USP28 integrates 53BP1 and MYC functions to limit DNA damage
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11024517/
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Membrane to cortex attachment determines different mechanical phenotypes in LGR5+ and LGR5- colorectal cancer cells
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11026456/
  52. aacrjournals.org aacrjournals.org
    PRMT1 inhibition activates the interferon pathway to potentiate antitumor immunity and enhance checkpoint blockade efficacy in melanoma
    1
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    aacrjournals.org/cancerres/article/84/3/419/733846/PRMT1-Inhibition-Activates-the-Interferon-Pathway
  53. www.sciencedirect.com www.sciencedirect.com
    Targeting high circDNA2v levels in colorectal cancer induces cellular senescence and elicits an anti-tumor secretome
    1
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    sciencedirect.com/science/article/pii/S221112472400439X
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Satellite double-stranded RNA induces mesenchymal transition in pancreatic cancer by regulating alternative splicing
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10943486/
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HOXA5-induced lncRNA DNM3OS promotes human embryo lung fibroblast fibrosis via recruiting EZH2 to epigenetically suppress TSC2 expression
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10944743/
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Profiling the role of m6A effectors in the regulation of pluripotent reprogramming
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10986062/
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    USP5 promotes tumorigenesis by activating Hedgehog/Gli1 signaling pathway in osteosarcoma
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10998757/
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Role of HIV-1-Encoded microRNAs in Viral Replication
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10971904/
  59. Mar 2024
  60. www.sciencedirect.com www.sciencedirect.com
    Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape
    1
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    sciencedirect.com/science/article/pii/S1097276524001758
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The BHLHE40‒PPM1F‒AMPK pathway regulates energy metabolism and is associated with the aggressiveness of endometrial cancer
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10904277/
  62. 52.53.155.43 52.53.155.43
    SHP-1 inhibition targets leukaemia stem cells to restore immunosurveillance and enhance chemosensitivity by metabolic reprogramming
    1
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    52.53.155.43/a85d3b9f92fdbe08a8488af8660c90612671e554/s41556-024-01349-3-html.html
  63. www.sciencedirect.com www.sciencedirect.com
    The CARD8 inflammasome dictates HIV/SIV pathogenesis and disease progression
    1
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    sciencedirect.com/science/article/pii/S009286742400117X
  64. Feb 2024
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intrahepatic homeobox protein MSX-1 is a novel host restriction factor of hepatitis B virus
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10878074/
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 and oncolytic EV-D68-encoded proteases differentially regulate pyroptosis
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10878271/
  67. www.biorxiv.org www.biorxiv.org
    BET Degraders Reveal BRD4 Disruption of 7SK and P-TEFb is Critical for Effective Reactivation of Latent HIV in CD4+ T-cells
    1
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    biorxiv.org/content/10.1101/2024.02.23.581756v1
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DUX4-r exerts a neomorphic activity that depends on GTF2I in acute lymphoblastic leukemia
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10881058/
  69. breast-cancer-research.biomedcentral.com breast-cancer-research.biomedcentral.com
    Small molecule inhibitor targeting the Hsp70-Bim protein–protein interaction in estrogen receptor-positive breast cancer overcomes tamoxifen resistance
    1
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    breast-cancer-research.biomedcentral.com/articles/10.1186/s13058-024-01790-0
  70. 52.53.155.43 52.53.155.43
    419-html.html
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    52.53.155.43/9ee9b923ebb85a391d8ef40b8ed2af8f0d12ae03/419-html.html
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oncoprotein SET-associated transcription factor ZBTB11 triggers lung cancer metastasis
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10867109/
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRL4B E3 ligase recruited by PRPF19 inhibits SARS-CoV-2 infection by targeting ORF6 for ubiquitin-dependent degradation
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10865787/
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of microtubule nucleation in mouse bone marrow-derived mast cells by ARF GTPase-activating protein GIT2
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10870779/
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GPX3 supports ovarian cancer tumor progression in vivo and promotes expression of GDF15
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10862694/
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Triple-Negative Breast Cancer Intrinsic FTSJ1 Favors Tumor Progression and Attenuates CD8+ T Cell Infiltration
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10854779/
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IGF-1R mediates crosstalk between nasopharyngeal carcinoma cells and osteoclasts and promotes tumor bone metastasis
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10860326/
  77. 52.53.155.43 52.53.155.43
    RNA-guided RNA silencing by an Asgard archaeal Argonaute
    1
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    52.53.155.43/299a104299b2de46de3d5132e96f6dd2d1482298/2023.12.14.571608v2.full-html.html
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Exploiting epigenetic targets to overcome taxane resistance in prostate cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10861560/
  79. www.sciencedirect.com www.sciencedirect.com
    Proline restores mitochondrial function and reverses aging hallmarks in senescent cells
    2
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    sciencedirect.com/science/article/pii/S2211124724000664
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EIF4A3-mediated biogenesis of circSTX6 promotes bladder cancer metastasis and cisplatin resistance
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10759346/
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The oncogenic role and regulatory mechanism of PGK1 in human non-small cell lung cancer
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10759362/
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mcam inhibits macrophage-mediated development of mammary gland through non-canonical Wnt signaling
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10761817/
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmaceutical targeting of OTUB2 sensitizes tumors to cytotoxic T cells via degradation of PD-L1
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10761827/
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SMAD4 inhibits glycolysis in ovarian cancer through PI3K/AKT/HK2 signaling pathway by activating ARHGAP10
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10849991/
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SMYD3 promotes endometrial cancer through epigenetic regulation of LIG4/XRCC4/XLF complex in non-homologous end joining repair
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10774296/
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting N-linked Glycosylation for the Therapy of Aggressive Lymphomas
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    ncbi.nlm.nih.gov/pmc/articles/PMC10524254/
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cytoplasmic accumulation and plasma membrane association of anillin and Ect2 promote confined migration and invasion
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    ncbi.nlm.nih.gov/pmc/articles/PMC10802709/
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BRMS1L confers anticancer activity in non-small cell lung cancer by transcriptionally inducing a redox imbalance in the GPX2-ROS pathway
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10832508/
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    c-Fos regulated by TMPO/ERK axis promotes 5-FU resistance via inducing NANOG transcription in colon cancer
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10794174/
  90. Jan 2024
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PICH deficiency limits the progression of MYC-induced B-cell lymphoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10803365/
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Caloric restriction leads to druggable LSD1-dependent cancer stem cells expansion
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    ncbi.nlm.nih.gov/pmc/articles/PMC10821871/
  93. dx.doi.org dx.doi.org
    Kaposi's sarcoma herpesvirus exploits the DNA damage response to circularize its genome
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