1,011 Matching Annotations
  1. Jul 2025
  2. www.sciencedirect.com www.sciencedirect.com
    MLKL activates the cGAS-STING pathway by releasing mitochondrial DNA upon necroptosis induction
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    sciencedirect.com/science/article/pii/S1097276525005052
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    Nucleotide-binding domain-like receptor protein 3 inflammasome contributes to vascular endothelial barrier dysfunction and shock after burn injury
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    sciencedirect.com/science/article/pii/S0305417925002189
  4. Jun 2025
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    Phenotypic screens for SIRPA expression reveal RAB21 as a general regulator of macrophage surface identity
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    sciencedirect.com/science/article/pii/S2211124725006928
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    B cell-derived nociceptin/orphanin FQ contributes to impaired glucose tolerance and insulin resistance in obesity
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    sciencedirect.com/science/article/pii/S2589004225010806
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    Cytokine-induced reprogramming of human macrophages toward Alzheimer’s disease-relevant molecular and cellular phenotypes in vitro
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    sciencedirect.com/science/article/pii/S2211124725006801
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Itaconate and obesity-related hormones promote tumor progression – new insights on metabolic dysfunction in early-onset colon cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12183228/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A guide to selecting high-performing antibodies for STING1 (Uniprot ID: Q86WV6) for use in western blot, immunoprecipitation, and immunofluorescence
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    pmc.ncbi.nlm.nih.gov/articles/PMC12175898/
  10. 52.53.155.43 52.53.155.43
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  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Immune targeting of triple-negative breast cancer through a clinically actionable STING agonist-CAR T cell platform
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    pmc.ncbi.nlm.nih.gov/articles/PMC12281382/
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Membrane-bound IL-15 co-expression powers a potent and persistent CD70-targeted TRuC T-cell therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12162932/
  13. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    7,4′-dimethoxy-3-hydroxyflavone, a protease-activated receptor 4 (PAR4) inhibitor with antioxidant activity, ameliorates diabetic endothelial dysfunction
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.70105
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    Exploring the antioxidant, antiglycation, and anti-inflammatory potential of Oroxylum indicum stem bark extracts
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    journals.plos.org/plosone/article
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    Dual Role for Pld1 in Klebsiella pneumoniae Virulence: Transcriptomics and Proteomics Provide Insights into Direct and Indirect Effects
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    pubs.acs.org/doi/full/10.1021/acs.jproteome.4c01146
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  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sustained Tenascin-C Expression Drives Neointimal Hyperplasia and Promotes Aortocaval Fistula Failure
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    pmc.ncbi.nlm.nih.gov/articles/PMC12150301/
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RNA shielding of P65 is required to potentiate oncogenic inflammation in TET2 mutated clonal hematopoiesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11611684/
  20. www.sciencedirect.com www.sciencedirect.com
    PGK1 phosphorylates NLRP3 and mediates inflammasome activation independent of its glycolytic activity
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    sciencedirect.com/science/article/pii/S221112472500556X
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    Centromeric DNA amplification triggered by viral proteins activates nuclear cGAS
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    sciencedirect.com/science/article/pii/S0092867425005562
  22. May 2025
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Phase transition of WTAP regulates m6A modification of interferon-stimulated genes
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    pmc.ncbi.nlm.nih.gov/articles/PMC12113268/
  24. www.nature.com www.nature.com
    Hybridization chain reaction-based DNA nanoframeworks for biosensing and therapeutic applications
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    nature.com/articles/s41596-025-01183-3
  25. www.cell.com www.cell.com
    CD97-directed CAR-T cells with enhanced persistence eradicate acute myeloid leukemia in diverse xenograft models
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    cell.com/cell-reports-medicine/fulltext/S2666-3791(25)00221-6
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Good manufacturing practice production of an off-the-shelf CD34+ progenitor-derived NK cell product with preserved anti-tumor functionality post-infusion in NOD/SCID/IL2Rgnull mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC12104124/
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    Stress-induced pro-inflammatory glioblastoma stem cells secrete TNFAIP6 to enhance tumor growth and induce suppressive macrophages
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    sciencedirect.com/science/article/pii/S1534580725002874
  28. elifesciences.org elifesciences.org
    ATP-release pannexin channels are gated by lysophospholipids
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    elifesciences.org/articles/107067
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Effects of Caffeine on THP-1 Myelogenous Cell Inflammatory Gene Expression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12025982/
  30. www.sciencedirect.com www.sciencedirect.com
    Tongue Squamous Cell Carcinoma-Derived Exosomes miR-21-5p Affect Tumor Progression via Promoting M2 Macrophage Polarization
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    sciencedirect.com/science/article/pii/S246805402500054X
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    The PYRIN domain is required for TLR4-mediated inflammation by PYHIN family members
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    sciencedirect.com/science/article/pii/S2589004225006741
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    Acute infectious mononucleosis generates persistent, functional EBNA-1 antibodies with high cross-reactivity to alpha-crystalline beta
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    sciencedirect.com/science/article/pii/S2211124725004802
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    The m5C methyltransferase NSUN2 promotes progression of acute myeloid leukemia by regulating serine metabolism
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    sciencedirect.com/science/article/pii/S2211124725004322
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    Phagosomal RNA sensing through TLR8 controls susceptibility to tuberculosis
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    sciencedirect.com/science/article/pii/S2211124725004280
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    Anti-dengue virus antibodies that elicit complement-mediated lysis of Zika virion correlate with protection from severe dengue disease
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    sciencedirect.com/science/article/pii/S2211124725003845
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    Engineering a three-dimensional liver steatosis model
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    sciencedirect.com/science/article/pii/S0925443925002364
  37. Apr 2025
  38. www.sciencedirect.com www.sciencedirect.com
    Reprogramming liver metastasis-associated macrophages toward an anti-tumoral phenotype through enforced miR-342 expression
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    sciencedirect.com/science/article/pii/S2211124725003638
  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PLK1 Inhibition Induces Synthetic Lethality in Fanconi Anemia Pathway–Deficient Acute Myeloid Leukemia
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    pmc.ncbi.nlm.nih.gov/articles/PMC12011380/
  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Colorectal cancer stem cells develop NK cell resistance via homotypic cell-in-cell structures suppressed by Stathmin1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11984389/
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Succinate receptor 1 signaling mutually depends on subcellular localization and cellular metabolism
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  42. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70031
  43. link.springer.com link.springer.com
    CD14 and NFKB-1 Serve as Essential Gatekeepers for Monitoring In Vitro Production of Pro-inflammatory Cytokines in THP-1 Monocytic Cells
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    link.springer.com/article/10.1007/s12291-025-01316-1
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Enhanced TLR7-dependent production of type I interferon by pDCs underlies pandemic chilblains
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    pmc.ncbi.nlm.nih.gov/articles/PMC11995862/
  45. 52.53.155.43 52.53.155.43
    Single-Nuclei Analysis of the Unfolded Protein Response (SNUPR): A Novel Method revealing bortezomib resistance mechanisms in Multiple Myeloma
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  46. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Analysis of mutually exclusive expression in cancer cells identifies a previously unknown intergenic regulatory paradigm
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.70089
  47. www.nature.com www.nature.com
    Heritable maintenance of chromatin modifications confers transcriptional memory of interferon-γ signaling
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    nature.com/articles/s41594-025-01522-8
  48. www.sciencedirect.com www.sciencedirect.com
    Maternal transfer of anti-GAPDH IgG prevents neonatal infections caused by Staphylococcus aureus and group B Streptococcus
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    sciencedirect.com/science/article/pii/S2589004225005097
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    Microneedle delivery of CAR-M-like engineered macrophages alleviates intervertebral disc degeneration through enhanced efferocytosis capacity
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    sciencedirect.com/science/article/pii/S2666379125001521
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A single amino acid in the Salmonella effector SarA/SteE triggers supraphysiological activation of STAT3 for anti-inflammatory gene expression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12014907/
  51. retrovirology.biomedcentral.com retrovirology.biomedcentral.com
    Aberrant expression of human endogenous retrovirus K9-derived elements is associated with better clinical outcome of acute myelocytic leukemia
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    retrovirology.biomedcentral.com/articles/10.1186/s12977-025-00661-6
  52. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Checkpoint Reversal Receptor Mediates Bipartite Activation and Enhances CAR T-cell Function
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    pmc.ncbi.nlm.nih.gov/articles/PMC11955954/
  53. www.cell.com www.cell.com
    Molecular parameters governing antibody FcγR signaling and effector functions in the context of HIV envelope
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    cell.com/cell-reports/fulltext/S2211-1247(25)00102-0
  54. 52.53.155.43 52.53.155.43
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    Highly potent quinoxalinediones inhibit α-hemolysin and ameliorate Staphylococcus aureus lung infections
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    sciencedirect.com/science/article/pii/S1931312825000897
  56. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    PPY-Induced iCAFs Cultivate an Immunosuppressive Microenvironment in Pancreatic Cancer
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202413432
  57. Mar 2025
  58. www.mdpi.com www.mdpi.com
    HTLV-1 p13 Protein Hijacks Macrophage Polarization and Promotes T-Cell Recruitment
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    mdpi.com/1999-4915/17/4/471
  59. www.sciencedirect.com www.sciencedirect.com
    EGR2 promotes liver cancer metastasis by enhancing IL-8 expression through transcription regulation of PDK4 in M2 macrophages
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    sciencedirect.com/science/article/pii/S1567576925004746
  60. www.sciencedirect.com www.sciencedirect.com
    Visualization of calpain-1 activation during cell death and its role in GSDMD cleavage using chemical probes
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    sciencedirect.com/science/article/pii/S2451945625000686
  61. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Myrobalan Fruit Extracts Modulate Immunobiochemical Pathways In Vitro
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    pmc.ncbi.nlm.nih.gov/articles/PMC11939258/
  62. www.sciencedirect.com www.sciencedirect.com
    A niche driven mechanism determines response and a mutation-independent therapeutic approach for myeloid malignancies
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    sciencedirect.com/science/article/pii/S1535610825001084
  63. 52.53.155.43 52.53.155.43
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  64. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mechanism Study of Bufalin Reversal of Drug Resistance by Inhibiting Hypoxic Colon Cancer Cell-Induced Polarization of M2 Macrophages
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    pmc.ncbi.nlm.nih.gov/articles/PMC11898227/
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    Simultaneous CRISPR screening and spatial transcriptomics reveal intracellular, intercellular, and functional transcriptional circuits
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  66. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    BKT300: A Novel Anti-Leukemic Small Molecule Targeting the Protein Regulator of Cytokinesis 1 (PRC1) Pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC11875301/
  67. link.springer.com link.springer.com
    Extracellular vesicular delivery of ceramides from pulmonary macrophages to endothelial cells facilitates chronic obstructive pulmonary disease
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    link.springer.com/article/10.1186/s12964-025-02125-y
  68. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Static magnetic fields alleviate diabetic nephropathy by reducing renal cell inflammation and promoting M2 macrophage polarization
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    faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.202500061R
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  70. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Changes in importin levels promote nuclear proteasomal degradation of cell cycle-related proteins during THP-1 monocyte-to-macrophage differentiation
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    febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.70020
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  72. Feb 2025
  73. www.sciencedirect.com www.sciencedirect.com
    OAS cross-activates RNase L intercellularly through cell-to-cell transfer of 2-5A to spread innate immunity
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    sciencedirect.com/science/article/pii/S1074761325000652
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    Piplartine alleviates sepsis-induced acute kidney injury by inhibiting TSPO-mediated macrophage pyroptosis
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  75. www.cell.com www.cell.com
    EZH1/EZH2 inhibition enhances adoptive T cell immunotherapy against multiple cancer models
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    cell.com/cancer-cell/abstract/S1535-6108(25)00031-5
  76. www.biorxiv.org www.biorxiv.org
    Spike-specific IgG4 generated post BNT162b2 mRNA vaccination is inhibitory when directly competing with functional IgG subclasses
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    biorxiv.org/content/10.1101/2025.02.12.637095v1
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    Nucleic-acid-induced ZCCHC3 condensation promotes broad innate immune responses
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  78. aacrjournals.org aacrjournals.org
    MR1 gene and protein expression are enhanced by inhibition of the extracellular signal-regulated kinase ERK
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    aacrjournals.org/cancerimmunolres/article/12/10/1452/748716/MR1-Gene-and-Protein-Expression-Are-Enhanced-by
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    ILT2 and ILT4 drive myeloid suppression via both overlapping and distinct mechanisms
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    aacrjournals.org/cancerimmunolres/article/12/5/592/745126/ILT2-and-ILT4-Drive-Myeloid-Suppression-via-Both
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    PSPC1 exerts an oncogenic role in AML by regulating a leukemic transcription program in cooperation with PU.1
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    sciencedirect.com/science/article/pii/S1934590925000104
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    EHF promotes liver cancer progression by meditating IL-6 secretion through transcription regulation of KDM2B in TAMs
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    sciencedirect.com/science/article/pii/S089865682500083X
  82. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    T3SS translocon induces pyroptosis by direct interaction with NLRC4/NAIP inflammasome
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    pmc.ncbi.nlm.nih.gov/articles/PMC11828483/
  83. www.cell.com www.cell.com
    Genomic mediators of acquired resistance to immunotherapy in metastatic melanoma
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    cell.com/cancer-cell/abstract/S1535-6108(25)00027-3
  84. www.mdpi.com www.mdpi.com
    Electrospun Silk Fibroin–Silk Sericin Scaffolds Induced Macrophage Polarization and Vascularization for Volumetric Muscle Loss Injury
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    mdpi.com/2079-4983/16/2/56
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    TCL1A in naïve B cells as a therapeutic target for type 1 diabetes
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    sciencedirect.com/science/article/pii/S2352396425000374
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    ArfGAP2 promotes STING proton channel activity, cytokine transit, and autoinflammation
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    sciencedirect.com/science/article/pii/S0092867425000960
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    Neutrophil-derived vesicles control complement activation to facilitate inflammation resolution
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    sciencedirect.com/science/article/pii/S0092867425000509
  88. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Immunoglobulin-like transcript 5 polarizes M2-like tumor-associated macrophages for immunosuppression in non-small cell lung cancer
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    onlinelibrary.wiley.com/doi/10.1002/ijc.35360
  89. www.sciencedirect.com www.sciencedirect.com
    TRIM65 regulates innate immune signaling by enhancing K6-linked ubiquitination of IRF3 and its chromatin recruitment
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    sciencedirect.com/science/article/pii/S2211124724013111
  90. 52.53.155.43 52.53.155.43
    Monovalent XBB.1.5 mRNA Vaccine Recalls a More Durable and Coordinated Antibody Response to SARS-CoV-2 Spike than the Bivalent WT/BA.5 mRNA Vaccine
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