646 Matching Annotations
  1. May 2025
  2. link.springer.com link.springer.com
    Reactivity-based metabolomics reveal cysteine has glyoxalase 1-like and glyoxalase 2-like activities
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    link.springer.com/article/10.1038/s41589-025-01909-0
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    1-s2.0-S2589004225009605-main-html.html
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    pmc.ncbi.nlm.nih.gov/articles/PMC12164204/
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    Progestogens reduce tau phosphorylation via ERK 1/2 in a tau overexpression cell model
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    sciencedirect.com/science/article/pii/S2666459325000563
  5. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.70120
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Adaptive protein synthesis in genetic models of copper deficiency and childhood neurodegeneration | Molecular Biology of the Cell
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    pmc.ncbi.nlm.nih.gov/articles/PMC11974963/
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    Extracellular matrix mechanical cues (dys)regulate metabolic redox homeostasis due to impaired autophagic flux
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    onlinelibrary.wiley.com/doi/10.1111/eci.70051
  8. 52.53.155.43 52.53.155.43
    1-s2.0-S1525001625003806-main-html.html
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    Analysis and Identification of Therapeutic Targets for Neuronal Regeneration After Ischemic Stroke
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    pmc.ncbi.nlm.nih.gov/articles/PMC12050405/
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    febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.70043
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    Novel miRNAs, miR-937-3p, miR-4536-3p, and miR-4650-5p, can Modulate Neuronal Differentiation via the Wnt/MAPK Pathway in SH-SY5Y Cells
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    link.springer.com/article/10.1007/s12035-025-05002-4
  12. Apr 2025
  13. www.sciencedirect.com www.sciencedirect.com
    The major component of Heteractis magnifica sea anemone venom, RpIII, exhibits strong subtype selectivity for insects over mammalian voltage-gated sodium channels
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    sciencedirect.com/science/article/pii/S0028390825001728
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70031
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    HMGA1 deficiency: a pathogenic link between tau pathology and insulin resistance
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    sciencedirect.com/science/article/pii/S2352396425001446
  16. 52.53.155.43 52.53.155.43
    1-s2.0-S1525001625002795-main-html.html
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    52.53.155.43/50ee16a498584d049fed89adec56a062179dbf25/PDF-html.html
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    Mitochondrial Damage and ER Stress in CB1 Receptor Antagonist-Induced Apoptosis in Human Neuroblastoma SH-SY5Y Cells
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    sciencedirect.com/science/article/pii/S0028390825001467
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    Excessive expression of progranulin leads to neurotoxicity rather than neuroprotection
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    sciencedirect.com/science/article/pii/S0969996125001111
  19. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Clioquinol induces mitochondrial toxicity in SH-SY5Y neuroblastoma cells by affecting the respiratory chain complex IV and OPA1 dynamin-like GTPase
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    febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.70033
  20. Mar 2025
  21. www.sciencedirect.com www.sciencedirect.com
    Seeded aggregation of TDP-43 induces its loss of function and reveals early pathological signatures
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    sciencedirect.com/science/article/pii/S0896627325001801
  22. www.biorxiv.org www.biorxiv.org
    17q21.31 locus regulates Parkinson’s disease relevant pathways through KANSL1 activity
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    biorxiv.org/content/10.1101/2025.03.17.641409v1
  23. www.cell.com www.cell.com
    Probing enzyme-dependent pseudouridylation using direct RNA sequencing to assess epitranscriptome plasticity in a neuronal cell line
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    cell.com/cell-systems/fulltext/S2405-4712(25)00071-7
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Bioengineering the metabolic network of CAR T cells with GLP-1 and Urolithin A increases persistence and long-term anti-tumor activity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11970383/
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Single extracellular vesicle detection assay identifies membrane-associated α-synuclein as an early-stage biomarker in Parkinson’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11970385/
  26. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    A non-redundant role of EAAT3 for ATP synthesis mediated by GDH in dopaminergic neuronal cells: a new avenue for glutamate metabolism and protection in Parkinson's disease
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.70053
  27. journals.lww.com journals.lww.com
    Comparative proteomic analysis of plasma exosomes reveals... : Neural Regeneration Research
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    journals.lww.com/nrronline/fulltext/2025/10000/comparative_proteomic_analysis_of_plasma_exosomes.29.aspx
  28. onlinelibrary.wiley.com onlinelibrary.wiley.com
    CPNE7 Regulates Amyloidogenesis Through CAP1-Dependent ADAM10 Translation
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    onlinelibrary.wiley.com/doi/10.1111/jnc.70026
  29. Feb 2025
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Evaluating Blood–Brain Barrier Permeability, Cytotoxicity, and Activity of Potential Acetylcholinesterase Inhibitors: In Vitro and In Silico Study
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    pmc.ncbi.nlm.nih.gov/articles/PMC11841676/
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13789
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    USP14 is crucial for proteostasis regulation and α-synuclein degradation in human SH-SY5Y dopaminergic cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11795799/
  33. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Direct Current Stimulation (DCS) Modulates Lipid Metabolism and Intercellular Vesicular Trafficking in SHSY-5Y Cell Line: Implications for Parkinson's Disease
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    onlinelibrary.wiley.com/doi/10.1111/jnc.70014
  34. www.sciencedirect.com www.sciencedirect.com
    Application of mRNA technology in neuronal protection of human mature brain-derived neurotrophic factor
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    sciencedirect.com/science/article/pii/S0040816625000680
  35. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Etoposide-induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13807
  36. onlinelibrary.wiley.com onlinelibrary.wiley.com
    FOXP1 is a Transcription Factor for the Alzheimer's Disease Risk Gene SORL1
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.70011
  37. www.sciencedirect.com www.sciencedirect.com
    Transmembrane Parkinson’s Disease mutation of PINK1 leads to altered mitochondrial anchoring
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    sciencedirect.com/science/article/pii/S0021925825001000
  38. link.springer.com link.springer.com
    Zerumbone-mediated post-ischemic neuroprotection: Reduction of ferroptosis through TFR1 downregulation in vitro
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    link.springer.com/article/10.1007/s11033-025-10301-z
  39. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    A cellular model of TDP-43 induces phosphorylated TDP-43 aggregation with distinct changes in solubility and autophagy dysregulation
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17413
  40. Jan 2025
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Serially Quantifying TERT Rearrangement Breakpoints in ctDNA Enables Minimal Residual Disease Monitoring in Patients with Neuroblastoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11774142/
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Spatial and Single-Cell Analyses Reveal Heterogeneity of DNAM-1 Receptor–Ligand Interactions That Instructs Intratumoral γδT-cell Activity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11733534/
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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    pmc.ncbi.nlm.nih.gov/articles/PMC12001157/
  44. elifesciences.org elifesciences.org
    Unbiased identification of cell identity in dense mixed neural cultures
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    elifesciences.org/articles/95273
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Regulation and Function of CCL2 and N-Myc in Retinoic Acid-treated Neuroblastoma Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11696317/
  46. www.sciencedirect.com www.sciencedirect.com
    Opposing roles of p38α-mediated phosphorylation and PRMT1-mediated arginine methylation in driving TDP-43 proteinopathy
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    sciencedirect.com/science/article/pii/S2211124724015560
  47. www.sciencedirect.com www.sciencedirect.com
    14–3-3θ phosphorylation exacerbates alpha-synuclein aggregation and toxicity
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    sciencedirect.com/science/article/pii/S0969996125000178
  48. www.sciencedirect.com www.sciencedirect.com
    G6PD deficiency triggers dopamine loss and the initiation of Parkinson’s disease pathogenesis
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    sciencedirect.com/science/article/pii/S2211124724015298
  49. Dec 2024
  50. elifesciences.org elifesciences.org
    Pathogenic Huntingtin aggregates alter actin organization and cellular stiffness resulting in stalled clathrin-mediated endocytosis
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    elifesciences.org/articles/98363
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Phosphorylation of Optineurin by protein kinase D regulates Parkin-dependent mitophagy
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    pmc.ncbi.nlm.nih.gov/articles/PMC11634986/
  52. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Proximity proteomic analysis of the NRF family reveals the Parkinson's disease protein ZNF746/PARIS as a co-complexed repressor of NRF2
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    pmc.ncbi.nlm.nih.gov/articles/PMC10760916/
  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Hsa_Circ_0105596/FTO inhibits progression of Parkinson's disease by sponging miR-187-3p and regulating eEF2
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    pmc.ncbi.nlm.nih.gov/articles/PMC11626004/
  54. 52.53.155.43 52.53.155.43
    Endoplasmic reticulum morphology regulation by RTN4 modulates neuronal regeneration by curbing luminal transport
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    52.53.155.43/a5cd2a76f55670a4ac26cd7a0c2f7cbc81f1256c/Endoplasmic reticulum morphology regulation by RTN4 modulates neu-html.html
  55. link.springer.com link.springer.com
    A rare genetic variant in APEX1 is associated with familial amyotrophic lateral sclerosis with slow progression
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    link.springer.com/article/10.1007/s13760-024-02692-w
  56. Nov 2024
  57. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dual inhibition of aminoacyl-tRNA synthetase interacting multifunctional protein-2 and α-synuclein by steroid derivative is neuroprotective in Parkinson’s model
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    pmc.ncbi.nlm.nih.gov/articles/PMC11576395/
  58. www.sciencedirect.com www.sciencedirect.com
    Microbiota-derived lysophosphatidylcholine alleviates Alzheimer’s disease pathology via suppressing ferroptosis
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    sciencedirect.com/science/article/pii/S1550413124004029
  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neurons enhance blood–brain barrier function via upregulating claudin-5 and VE-cadherin expression due to glial cell line-derived neurotrophic factor secretion
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    pmc.ncbi.nlm.nih.gov/articles/PMC11524583/
  60. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Hub genes and key pathways of traumatic brain injury:... : Neural Regeneration Research
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    pmc.ncbi.nlm.nih.gov/articles/PMC10233762/
  61. 52.53.155.43 52.53.155.43
    enhanced_autophagic_clearance_of_amyloid___via.25-html.html
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  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TREM-1 mediates interaction between substantia nigra microglia and peripheral neutrophils
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    ncbi.nlm.nih.gov/pmc/articles/PMC11467918/
  63. Oct 2024
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Adaptive protein synthesis in genetic models of copper deficiency and childhood neurodegeneration
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    ncbi.nlm.nih.gov/pmc/articles/PMC11419079/
  65. aacrjournals.org aacrjournals.org
    Design of a Cytotoxic Neuroblastoma-Targeting Agent Using an Enzyme Acting on Polysialic Acid Fused to a Toxin
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    aacrjournals.org/mct/article/20/10/1996/665734/Design-of-a-Cytotoxic-Neuroblastoma-Targeting
  66. Sep 2024
  67. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Amyloid beta 1-40 and 1-42 fibril ratios and maturation level cause conformational differences with minimal impact on autophagy and cytotoxicity
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    onlinelibrary.wiley.com/doi/10.1111/jnc.16201
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    GPR40 agonist ameliorates neurodegeneration and motor impairment by regulating NLRP3 inflammasome in Parkinson’s disease animal models
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    sciencedirect.com/science/article/pii/S1043661824003773
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    eIF2B localisation and its regulation during the integrated stress response is cell-type specific
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    sciencedirect.com/science/article/pii/S2589004224020765
  70. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Combined inhibition of RAD51 and CHK1 causes synergistic toxicity in cisplatin resistant cancer cells by triggering replication fork collapse
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    onlinelibrary.wiley.com/doi/full/10.1002/ijc.35164
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    febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.15010
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17208
  73. Aug 2024
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterizing Relationships between T-cell Inflammation and Outcomes in Patients with High-Risk Neuroblastoma According to Mesenchymal and Adrenergic Signatures
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    ncbi.nlm.nih.gov/pmc/articles/PMC11350481/
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IER3IP1-mutations cause microcephaly by selective inhibition of ER-Golgi transport
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    ncbi.nlm.nih.gov/pmc/articles/PMC11335259/
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    ALS-FUS mutations cause abnormal PARylation and histone H1.2 interaction, leading to pathological changes
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    sciencedirect.com/science/article/pii/S2211124724009768
  77. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Intergenerational Epigenetic Inheritance Mediated by MYS-2/MOF in the Pathogenesis of Alzheimer’s Disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11363564/
  78. link.springer.com link.springer.com
    A Complex Interplay Between Melatonin and RORβ: RORβ is Unlikely a Putative Receptor for Melatonin as Revealed by Biophysical Assays
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    link.springer.com/article/10.1007/s12035-024-04395-y
  79. www.biorxiv.org www.biorxiv.org
    Antiviral immunity within neural stem cells distinguishes viral strain differences in forebrain organoids
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    biorxiv.org/content/10.1101/2024.07.09.602767v1
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    SIRT1 improves lactate homeostasis in the brain to alleviate parkinsonism via deacetylation and inhibition of PKM2
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    sciencedirect.com/science/article/pii/S2666379124004051
  81. www.biorxiv.org www.biorxiv.org
    L-glyceraldehyde inhibits neuroblastoma cell growth via a multi-modal mechanism on metabolism and signaling
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    biorxiv.org/content/10.1101/2023.12.20.572547v2
  82. actaneurocomms.biomedcentral.com actaneurocomms.biomedcentral.com
    Stimulating VAPB-PTPIP51 ER-mitochondria tethering corrects FTD/ALS mutant TDP43 linked Ca2+ and synaptic defects
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    actaneurocomms.biomedcentral.com/articles/10.1186/s40478-024-01742-x
  83. Jul 2024
  84. www.sciencedirect.com www.sciencedirect.com
    Translocational attenuation mediated by the PERK-SRP14 axis is a protective mechanism of unfolded protein response
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    sciencedirect.com/science/article/pii/S2211124724007307
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13702
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Alzheimer’s disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC11259434/
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    Arrestin-3-assisted activation of JNK3 mediates dopaminergic behavioral sensitization
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    sciencedirect.com/science/article/pii/S2666379124003276
  88. onlinelibrary.wiley.com onlinelibrary.wiley.com
    SH-SY5Y cells undergo changes in peroxisomal metabolism when exposed to decanoic acid
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    onlinelibrary.wiley.com/doi/10.1111/jnc.16185
  89. link.springer.com link.springer.com
    Kufor-Rakeb syndrome-associated psychosis: a novel loss-of-function ATP13A2 variant and response to antipsychotic therapy
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    link.springer.com/article/10.1007/s10048-024-00767-7
  90. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MGST3 regulates BACE1 protein translation and amyloidogenesis by controlling the RGS4-mediated AKT signaling pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC11332907/
  91. 52.53.155.43 52.53.155.43
    Endoplasmic reticulum morphology regulation by RTN4 modulates neuronal regeneration by curbing luminal transport
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    52.53.155.43/a5cd2a76f55670a4ac26cd7a0c2f7cbc81f1256c/Endoplasmic reticulum morphology regulation by RTN4 modulates neu-html.html
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multicellular, IVT-derived, unmodified human transcriptome for nanopore-direct RNA analysis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11221353/
  93. elifesciences.org elifesciences.org
    Novel autophagy inducers by accelerating lysosomal clustering against Parkinson’s disease
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    elifesciences.org/articles/98649
  94. Jun 2024
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  203. Feb 2023
  204. link.springer.com link.springer.com
    Genes critical for development and differentiation of dopaminergic neurons are downregulated in Parkinson’s disease
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    Bioluminescent RIPoptosome Assay for FADD/RIPK1 Interaction Based on Split Luciferase Assay in a Human Neuroblastoma Cell Line SH-SY5Y
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  207. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  208. Jan 2023
  209. link.springer.com link.springer.com
    CNTNAP2 Protein Is Degraded by the Ubiquitin–Proteasome System and the Macroautophagy-Lysosome Pathway
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    Cocaine-regulated trafficking of dopamine transporters in cultured neurons revealed by a pH sensitive reporter
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  215. Dec 2022
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    Mutant SOD1 aggregates formed in vitro and in cultured cells are polymorphic and differ from those arising in the CNS
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    Quantification of substoichiometric tRNA modification sites reveals global hypomodification of tsRNA, indicates preferences for angiogenin-mediated tRNA cleavage, and points to idiosyncratic tRNA epitranscriptomes of human neuronal cell lines
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    Targeting ARHGEF12 promotes neuroblastoma differentiation, MYCN degradation, and reduces tumorigenicity
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    Essential role of the mitochondrial Na+/Ca2+ exchanger NCLX in mediating PDE2-dependent neuronal survival and learning
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    Characterization of huntingtin interactomes and their dynamic responses in living cells by proximity proteomics
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