616 Matching Annotations
  1. Feb 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Degradation of AZGP1 suppresses apoptosis and facilitates cholangiocarcinoma tumorigenesis via TRIM25
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    ncbi.nlm.nih.gov/pmc/articles/PMC10844717/
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    Functionalized tetrahedral DNA frameworks for the capture of circulating tumor cells
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    link.springer.com/article/10.1038/s41596-023-00943-3
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    Locus-level L1 DNA methylation profiling reveals the epigenetic and transcriptional interplay between L1s and their integration sites
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    sciencedirect.com/science/article/pii/S2666979X24000259
  5. Jan 2024
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Overexpression of salusin-α upregulates AdipoR2 and activates the PPARα/ApoA5/SREBP-1c pathway to inhibit lipid synthesis in HepG2 cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10094946/
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    IL32 downregulation lowers triglycerides and type I collagen in di-lineage human primary liver organoids
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    sciencedirect.com/science/article/pii/S2666379123005694
  8. www.science.org www.science.org
    SUMOylated IL-33 in the nucleus stabilizes the transcription factor IRF1 in hepatocellular carcinoma cells to promote immune escape
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    science.org/doi/10.1126/scisignal.abq3362
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    Metabolomic analysis of a selective ABCA1 inducer in obesogenic challenge provides a rationale for therapeutic development
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    sciencedirect.com/science/article/pii/S2352396421000803
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    The mitochondrial genome-encoded peptide MOTS-c interacts with Bcl-2 to alleviate nonalcoholic steatohepatitis progression
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    sciencedirect.com/science/article/pii/S2211124723015991
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    Discovery of dual-active ethionamide boosters inhibiting the Mycobacterium tuberculosis ESX-1 secretion system
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    sciencedirect.com/science/article/pii/S2451945623004361
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    Olgotrelvir, a dual inhibitor of SARS-CoV-2 Mpro and cathepsin L, as a standalone antiviral oral intervention candidate for COVID-19
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    sciencedirect.com/science/article/pii/S2666634023004026
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    DNA methylation-mediated epigenetic regulation of oncogenic RPS2 as a novel therapeutic target and biomarker in hepatocellular carcinoma
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    sciencedirect.com/science/article/pii/S0006291X23015474
  14. Dec 2023
  15. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Histone methyltransferase SUV420H1/KMT5B contributes to poor prognosis in hepatocellular carcinoma
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    onlinelibrary.wiley.com/doi/10.1111/cas.16038
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mtfp1 ablation enhances mitochondrial respiration and protects against hepatic steatosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10733382/
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    PRMT blockade induces defective DNA replication stress response and synergizes with PARP inhibition
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    sciencedirect.com/science/article/pii/S2666379123005438
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    Chlorogenic acid regulates the expression of NPC1L1 and HMGCR through PXR and SREBP2 signaling pathways and their interactions with HSP90 to maintain cholesterol homeostasis
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    sciencedirect.com/science/article/pii/S0944711323006293
  19. link.springer.com link.springer.com
    SUMOylation inhibitors activate anti-tumor immunity by reshaping the immune microenvironment in a preclinical model of hepatocellular carcinoma
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    link.springer.com/article/10.1007/s13402-023-00880-z
  20. www.nature.com www.nature.com
    Discovery of a Drug-like, Natural Product-Inspired DCAF11 Ligand Chemotype
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    nature.com/articles/s41467-023-43657-6
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    Direct tumor irradiation potentiates adoptive NK cell targeting against parental and stem-like cancer in human liver cancer models.
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    sciencedirect.com/science/article/pii/S0360301623081518
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sex difference in liver diseases: How preclinical models help to dissect the sex-related mechanisms sustaining NAFLD and hepatocellular carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10682354/
  23. Nov 2023
  24. www.sciencedirect.com www.sciencedirect.com
    Abundant binary promoter switches in lineage-determining transcription factors indicate a digital component of cell fate determination
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    sciencedirect.com/science/article/pii/S2211124723014663
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    Anti-tumor effect of PD-L1-targeting antagonistic aptamer-ASO delivery system with dual inhibitory function in immunotherapy
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    sciencedirect.com/science/article/pii/S2451945623003719
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    The Role of KLF2 in Regulating Hepatic Lipogenesis and Blood Cholesterol Homeostasis via the SCAP/SREBP Pathway
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    sciencedirect.com/science/article/pii/S0022227523001451
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR/Cas9 screen for genome‐wide interrogation of essential MYC‐bound E‐boxes in cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10620128/
  28. www.nature.com www.nature.com
    Decreased B4GALT1 promotes hepatocellular carcinoma cell invasiveness by regulating the laminin-integrin pathway
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    nature.com/articles/s41389-023-00494-y
  29. Oct 2023
  30. www.sciencedirect.com www.sciencedirect.com
    Lactate activates the mitochondrial electron transport chain independently of its metabolism
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    sciencedirect.com/science/article/pii/S1097276523008006
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    Targeting HSP70 chaperones by rhein sensitizes liver cancer to artemisinin derivatives
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    sciencedirect.com/science/article/pii/S0944711323005159
  32. link.springer.com link.springer.com
    Comparative genomic analysis of Mycoplasma related to cell culture for infB gene-based loop-mediated isothermal amplification
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    link.springer.com/article/10.1007/s11274-023-03794-y
  33. 52.53.155.43 52.53.155.43
    FEBS Press
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    52.53.155.43/dbe8c3e3fbcbeef5c4f8f35843262b8cfb5dca0c/Molecular Oncology - 2023 - Liu - USP7 reduces the level of nuclear DICER impairing DNA damage response and promoting-html.html
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    Some Novel Bioactivities of Virgibacillus halodenitrificans Carotenoids, Isolated from Wadi El-Natrun Lakes
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    sciencedirect.com/science/article/pii/S1319562X2300270X
  35. 52.53.155.43 52.53.155.43
    BPS Publications
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    52.53.155.43/afcfaba631c42729b5026639051e5d935db9dc0d/British J Pharmacology - 2023 - Lou - Identification and pre-clinical investigation of CKBA as a drug for external use to-html.html
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    A bifunctional anti-PCSK9 scFv/Exendin-4 fusion protein exhibits enhanced lipid-lowering effects via targeting multiple signaling pathways in HFD-fed mice
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    sciencedirect.com/science/article/pii/S0141813023039004
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Atlas of primary cell-type-specific sequence models of gene expression and variant effects
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    ncbi.nlm.nih.gov/pmc/articles/PMC10545936/
  38. www.sciencedirect.com www.sciencedirect.com
    The senescent secretome drives PLVAP expression in cultured human hepatic endothelial cells to promote monocyte transmigration
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    sciencedirect.com/science/article/pii/S2589004223020436
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    Regulation of ERK2 activity by dynamic S-acylation
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    sciencedirect.com/science/article/pii/S2211124723011476
  40. Sep 2023
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synergism of the receptor tyrosine kinase Axl with ErbB receptors mediates resistance to regorafenib in hepatocellular carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10514905/
  42. 52.53.155.43 52.53.155.43
    Molecular Oncology - 2023 - Azbazdar-html.html
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    52.53.155.43/70328c8d0caa71a4e2e1443034607f137acd5326/Molecular Oncology - 2023 - Azbazdar-html.html
  43. 52.53.155.43 52.53.155.43
    The FEBS Journal - 2023 - Takeuchi-html.html
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    52.53.155.43/1a52c544b293ec29827fcbda62621cbc0bb29fbf/The FEBS Journal - 2023 - Takeuchi-html.html
  44. www.sciencedirect.com www.sciencedirect.com
    Identification of a natural PLA2 inhibitor from the marine fungus Aspergillus sp. c1 for MAFLD treatment that suppressed lipotoxicity by inhibiting the IRE-1α/XBP-1s axis and JNK signaling
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    sciencedirect.com/science/article/pii/S2211383523003398
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Alternative promoters and splicing create multiple functionally distinct isoforms of oestrogen receptor alpha in breast cancer and healthy tissues
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    ncbi.nlm.nih.gov/pmc/articles/PMC10557849/
  46. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Kleszcz-html.html
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    52.53.155.43/bda5ca2ff5fc6352261b5aa6b5327e2f6367b095/British J Pharmacology - 2023 - Kleszcz-html.html
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In vitro CRISPR screening uncovers CRTC3 as a regulator of IFN-γ-induced ferroptosis of hepatocellular carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10477178/
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SLAMF1 is expressed and secreted by Hepatocytes and the Liver in Non-Alcoholic Fatty Liver Disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC9377786/
  49. Aug 2023
  50. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    A combination of 5/6-nephrectomy and unilateral ureteral obstruction model accelerates progression of remote organ fibrosis in chronic kidney disease
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    faseb.onlinelibrary.wiley.com/doi/full/10.1096/fba.2023-00045
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    F-box only protein 2 exacerbates non-alcoholic fatty liver disease by targeting the hydroxyl CoA dehydrogenase alpha subunit
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    ncbi.nlm.nih.gov/pmc/articles/PMC10415968/
  52. www.biorxiv.org www.biorxiv.org
    TIM3 is a context-dependent co-regulator of cytotoxic T cell function
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    biorxiv.org/content/10.1101/2023.08.03.551797v1
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial UQCC3 controls embryonic and tumor angiogenesis by regulating VEGF expression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10393800/
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Vitamin B2 enables regulation of fasting glucose availability
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    ncbi.nlm.nih.gov/pmc/articles/PMC10328530/
  55. Jul 2023
  56. www.sciencedirect.com www.sciencedirect.com
    A spatially defined human Notch receptor interaction network reveals Notch intracellular storage and Ataxin-2-mediated fast recycling
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    sciencedirect.com/science/article/pii/S2211124723008306
  57. www.sciencedirect.com www.sciencedirect.com
    Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice
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    sciencedirect.com/science/article/pii/S2211124723008239
  58. www.sciencedirect.com www.sciencedirect.com
    An HBV susceptibility variant of KNG1 modulates the therapeutic effects of interferons α and λ1 in HBV infection by promoting MAVS lysosomal degradation
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    sciencedirect.com/science/article/pii/S2352396423002591
  59. www.sciencedirect.com www.sciencedirect.com
    PPM1H is down-regulated by ATF6 and dephosphorylates p-RPS6KB1 to inhibit progression of hepatocellular carcinoma
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    sciencedirect.com/science/article/pii/S2162253123001634
  60. www.nature.com www.nature.com
    E3 ligase MG53 suppresses tumor growth by degrading cyclin D1
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    nature.com/articles/s41392-023-01458-9
  61. www.sciencedirect.com www.sciencedirect.com
    Biological response and cell death signaling pathways modulated by tetrahydroisoquinoline-based aldoximes in human cells
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    sciencedirect.com/science/article/pii/S0300483X23001749
  62. 52.53.155.43 52.53.155.43
    BPS Publications
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    52.53.155.43/84e22c8ffa48b54196e02c1859b69baccf28c053/British J Pharmacology - 2023 - Ma - Role of circadian clock in the chronoefficacy and chronotoxicity of clopidogrel-html.html
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    Upregulation of FAM50A promotes cancer development
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    link.springer.com/article/10.1007/s12032-023-02072-z
  64. Jun 2023
  65. www.sciencedirect.com www.sciencedirect.com
    QKI shuttles internal m7G-modified transcripts into stress granules and modulates mRNA metabolism
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    sciencedirect.com/science/article/pii/S0092867423005986
  66. www.sciencedirect.com www.sciencedirect.com
    Peptide-mediated inhibition of the transcriptional regulator Elongin BC induces apoptosis in cancer cells
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    sciencedirect.com/science/article/pii/S2451945623001551
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The generation of HepG2 transmitochondrial cybrids to reveal the role of mitochondrial genotype in idiosyncratic drug-induced liver injury
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    ncbi.nlm.nih.gov/pmc/articles/PMC10270688/
  68. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Effect of Citrus bergamia extract on lipid profile: A combined in vitro and human study
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    onlinelibrary.wiley.com/doi/10.1002/ptr.7897
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activating an Adaptive Immune Response with a Telomerase-mediated Telomere Targeting Therapeutic in Hepatocellular Carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10233358/
  70. aacrjournals.org aacrjournals.org
    HBx-induced HSPA8 stimulates HBV replication and suppresses ferroptosis to support liver cancer progression
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    aacrjournals.org/cancerres/article/83/7/1048/718997/HBx-Induced-HSPA8-Stimulates-HBV-Replication-and
  71. www.science.org www.science.org
    Alternative splicing of GSDMB modulates killer lymphocyte–triggered pyroptosis
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    science.org/doi/10.1126/sciimmunol.adg3196
  72. 52.53.155.43 52.53.155.43
    mct-23-0039-html.html
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  73. May 2023
  74. www.sciencedirect.com www.sciencedirect.com
    Targeting of Annexin A1 in Tumor-associated Macrophages as a Therapeutic Strategy for Hepatocellular Carcinoma
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    sciencedirect.com/science/article/pii/S0006295223002034
  75. 52.53.155.43 52.53.155.43
    A novel EGFR Inhibitor, HNPMI regulates apoptosis and oncogenesis by modulating BCL-2/BAX and p53 in colon cancer
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    52.53.155.43/b51f94c49df43022b2f6198ee4b9b06582c4cb71/British J Pharmacology - 2023 - Kandhavelu - A novel EGFR Inhibitor HNPMI regulates apoptosis and oncogenesis by-html.html
  76. www.sciencedirect.com www.sciencedirect.com
    A PCR protocol to establish standards for routine mycoplasma testing that by design detects over ninety percent of all known mycoplasma species
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    sciencedirect.com/science/article/pii/S2589004223008015
  77. www.sciencedirect.com www.sciencedirect.com
    A hypometabolic defense strategy against malaria
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    sciencedirect.com/science/article/pii/S1550413122002315
  78. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Relationship between Maturity Stage, Triterpenoid Content and Cytotoxicity of Sorbus intermedia (EHRH.) PERS. Fruits – A Chemometric Approach
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    onlinelibrary.wiley.com/doi/full/10.1002/cbdv.202100552
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive Metabolic Tracing Reveals the Origin and Catabolism of Cysteine in Mammalian Tissues and Tumors
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    ncbi.nlm.nih.gov/pmc/articles/PMC10152234/
  80. Apr 2023
  81. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Deletion of the tyrosine phosphatase Shp2 in cervical cancer cells promotes reprogramming of glutamine metabolism
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202202078RR
  82. www.sciencedirect.com www.sciencedirect.com
    A hyper-quiescent chromatin state formed during aging is reversed by regeneration
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    sciencedirect.com/science/article/pii/S1097276523002496
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cell culture systems for isolation of SARS-CoV-2 clinical isolates and generation of recombinant virus
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    ncbi.nlm.nih.gov/pmc/articles/PMC10083141/
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of Membrane-expressed CAPRIN-1 as a Novel and Universal Cancer Target, and Generation of a Therapeutic Anti-CAPRIN-1 Antibody TRK-950
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    ncbi.nlm.nih.gov/pmc/articles/PMC10112292/
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Massively parallel characterization of transcriptional regulatory elements in three diverse human cell types
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    ncbi.nlm.nih.gov/pmc/articles/PMC10028905/
  86. www.sciencedirect.com www.sciencedirect.com
    Macrophage CD5L is a target for cancer immunotherapy
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    sciencedirect.com/science/article/pii/S2352396423001202
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: Targeting tumor vasculature to improve antitumor activity of T cells armed ex vivo with T cell engaging bispecific antibody
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    ncbi.nlm.nih.gov/pmc/articles/PMC10069597/
  88. Mar 2023
  89. www.biorxiv.org www.biorxiv.org
    A hyper-quiescent chromatin state formed during aging is reversed by regeneration
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    biorxiv.org/content/10.1101/2023.02.14.528512v1
  90. link.springer.com link.springer.com
    Upregulation of TUBG1 expression promotes hepatocellular carcinoma development
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    link.springer.com/article/10.1007/s12032-023-01966-2
  91. www.sciencedirect.com www.sciencedirect.com
    An optimized protocol to detect protein ubiquitination and activation by ubiquitination assay in vivo and CCK-8 assay
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    sciencedirect.com/science/article/pii/S2666166723001570
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    Allosteric targeting resolves limitations of earlier LFA-1 directed modalities
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    sciencedirect.com/science/article/pii/S0006295223000953
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting the recurrent Rac1P29S neoepitope in melanoma with heterologous high-affinity T cell receptors
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    ncbi.nlm.nih.gov/pmc/articles/PMC9978334/
  94. www.biorxiv.org www.biorxiv.org
    A Drug Repurposing Approach Reveals Targetable Epigenetic Pathways in Plasmodium vivax Hypnozoites
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    biorxiv.org/content/10.1101/2023.01.31.526483v3
  95. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16047
  96. Feb 2023
  97. www.sciencedirect.com www.sciencedirect.com
    PIMT regulates Hepatic Gluconeogenesis in Mice
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