518 Matching Annotations
  1. Dec 2022
  2. www.sciencedirect.com www.sciencedirect.com
    Discovery of a potent allosteric activator of DGKQ that ameliorates obesity-induced insulin resistance via the sn-1,2-DAG-PKCε signaling axis
    1
    1. scibot 17 Dec 2022
      HB-8065

      DOI: 10.1016/j.cmet.2022.11.012

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    sciencedirect.com/science/article/pii/S1550413122005034
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Implications of differential transcription start site selection on chronic myeloid leukemia and prostate cancer cell protein expression
    1
    1. scibot 02 Dec 2022
      RRID:CVCL_0027

      DOI: 10.1016/j.isci.2022.105519

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    ncbi.nlm.nih.gov/pmc/articles/PMC9678739/
  4. Nov 2022
  5. www.sciencedirect.com www.sciencedirect.com
    circPRKAA1 activates a Ku80/Ku70/SREBP-1 axis driving de novo fatty acid synthesis in cancer cells
    1
    1. scibot 23 Nov 2022
      HB-8065

      DOI: 10.1016/j.celrep.2022.111707

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    sciencedirect.com/science/article/pii/S2211124722015819
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PARP10 Mediates Mono-ADP-Ribosylation of Aurora-A Regulating G2/M Transition of the Cell Cycle
    1
    1. scibot 18 Nov 2022
      RRID:CVCL_0027

      DOI: 10.3390/cancers14215210

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    ncbi.nlm.nih.gov/pmc/articles/PMC9659153/
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The HSF1-CPT1a Pathway Is Differentially Regulated in NAFLD Progression
    1
    1. scibot 17 Nov 2022
      RRID:CVCL_0027

      DOI: 10.3390/cells11213504

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    ncbi.nlm.nih.gov/pmc/articles/PMC9655849/
  8. www.nature.com www.nature.com
    Promoting anti-tumor immunity by targeting TMUB1 to modulate PD-L1 polyubiquitination and glycosylation
    1
    1. scibot 17 Nov 2022
      RRID:CVCL_0027

      DOI: 10.1038/s41467-022-34346-x

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    nature.com/articles/s41467-022-34346-x
  9. www.sciencedirect.com www.sciencedirect.com
    Pan-cancer analysis of tissue and single-cell HIF-pathway activation using a conserved gene signature
    1
    1. scibot 16 Nov 2022
      RRID:CVCL_0027

      DOI: 10.1016/j.celrep.2022.111652

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    sciencedirect.com/science/article/pii/S2211124722015236
  10. www.sciencedirect.com www.sciencedirect.com
    STAT3 is activated by CTGF-mediated tumor-stroma cross talk to promote HCC progression.
    1
    1. scibot 10 Nov 2022
      RRID:CVCL_0027

      DOI: 10.1016/j.jcmgh.2022.09.006

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    sciencedirect.com/science/article/pii/S2352345X22001989
  11. Oct 2022
  12. www.sciencedirect.com www.sciencedirect.com
    Argininosuccinate lyase drives activation of mutant TERT promoter in glioblastomas
    1
    1. scibot 22 Oct 2022
      Cat# HB-8065

      DOI: 10.1016/j.molcel.2022.09.024

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    sciencedirect.com/science/article/pii/S1097276522009340
  13. elifesciences.org elifesciences.org
    Spatial modeling reveals nuclear phosphorylation and subcellular shuttling of YAP upon drug-induced liver injury
    1
    1. scibot 19 Oct 2022
      ATCC-HB-8065

      DOI: 10.7554/eLife.78540

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      Curator: @dbetts

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    elifesciences.org/articles/78540
  14. www.sciencedirect.com www.sciencedirect.com
    Sorbitol dehydrogenase induction of cancer cell necroptosis and macrophage polarization in the HCC microenvironment suppresses tumor progression
    1
    1. scibot 19 Oct 2022
      RRID: CVCL_0027

      DOI: 10.1016/j.canlet.2022.215960

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    sciencedirect.com/science/article/pii/S0304383522004475
  15. www.sciencedirect.com www.sciencedirect.com
    Cytoplasmic SIRT6-mediated ACSL5 deacetylation impedes nonalcoholic fatty liver disease by facilitating hepatic fatty acid oxidation
    1
    1. scibot 09 Oct 2022
      Cat# HB-8065

      DOI: 10.1016/j.molcel.2022.09.018

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    sciencedirect.com/science/article/pii/S1097276522009078
  16. www.sciencedirect.com www.sciencedirect.com
    Preparation of mitochondrial damage-associated molecular patterns from mouse liver tissue
    1
    1. scibot 04 Oct 2022
      RRID:CVCL_0027

      DOI: 10.1016/j.xpro.2022.101738

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    sciencedirect.com/science/article/pii/S2666166722006189
  17. www.sciencedirect.com www.sciencedirect.com
    “Disruption of the molecular clock severely affects lipid metabolism in a Hepatocellular Carcinoma Cell model”
    1
    1. scibot 01 Oct 2022
      RRID:CVCL_0027

      DOI: 10.1016/j.jbc.2022.102551

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    sciencedirect.com/science/article/pii/S0021925822009954
  18. Sep 2022
  19. www.jci.org www.jci.org
    Hematopoietic transcription factor GFI1 promotes anchorage independence by sustaining ERK activity in cancer cells
    1
    1. scibot 30 Sep 2022
      RRID:CVCL_0027

      DOI: 10.1172/JCI149551

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    jci.org/articles/view/149551
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Decellularization of xenografted tumors provides cell-specific in vitro 3D environment
    1
    1. scibot 03 Sep 2022
      CVCL_0027

      DOI: 10.3389/fonc.2022.956940

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    ncbi.nlm.nih.gov/pmc/articles/PMC9434107/
  21. Aug 2022
  22. 52.53.155.43 52.53.155.43
    149551.1-20220712091612-covered-e0fd13ba177f913fd3156f593ead4cfd-html.html
    1
    1. scibot 28 Aug 2022
      RRID:CVCL_0027

      DOI: 10.1172/jci149551

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    52.53.155.43/6cce47c11538cf17ab6233a5357637d51d293e1a/149551.1-20220712091612-covered-e0fd13ba177f913fd3156f593ead4cfd-html.html
  23. journals.physiology.org journals.physiology.org
    SLAMF1 is expressed and secreted by hepatocytes and the liver in nonalcoholic fatty liver disease
    2
    1. scibot 12 Aug 2022
      RRID:CVCL_0027

      DOI: 10.1152/ajpgi.00289.2021

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    2. scibot 12 Aug 2022
      RRID:CVCL_0027

      DOI: 10.1152/ajpgi.00289.2021

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    journals.physiology.org/doi/10.1152/ajpgi.00289.2021
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitotane Targets Lipid Droplets to Induce Lipolysis in Adrenocortical Carcinoma
    1
    1. scibot 06 Aug 2022
      RRID:CVCL_0027

      DOI: 10.1210/endocr/bqac102

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    ncbi.nlm.nih.gov/pmc/articles/PMC9342684/
  25. Jul 2022
  26. www.sciencedirect.com www.sciencedirect.com
    Acetylation of p62 regulates base excision repair through interaction with APE1
    1
    1. scibot 27 Jul 2022
      ATCCHB-8065

      DOI: 10.1016/j.celrep.2022.111116

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    sciencedirect.com/science/article/pii/S2211124722009226
  27. www.sciencedirect.com www.sciencedirect.com
    GCN2 inhibition sensitizes arginine-deprived hepatocellular carcinoma cells to senolytic treatment
    1
    1. scibot 15 Jul 2022
      RRID:CVCL_0027

      DOI: 10.1016/j.cmet.2022.06.010

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    sciencedirect.com/science/article/pii/S1550413122002303
  28. www.sciencedirect.com www.sciencedirect.com
    RPA1 controls chromatin architecture and maintains lipid metabolic homeostasis
    1
    1. scibot 13 Jul 2022
      ATCCHB-8065

      DOI: 10.1016/j.celrep.2022.111071

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    sciencedirect.com/science/article/pii/S2211124722008695
  29. Jun 2022
  30. 52.53.155.43 52.53.155.43
    Bergenin Attenuates Sodium Selenite-Induced Hepatotoxicity via Improvement of Hepatic Oxidant-Antioxidant Balance in HepG2 Cells and ICR Mice
    4
    1. scibot 28 Jun 2022
      RRID:CVCL_0027

      DOI: 10.1080/22311866.2021.1908162

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    2. scibot 24 Jun 2022
      RRID:CVCL_0027

      DOI: 10.1080/22311866.2021.1908162

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    3. scibot 22 Jun 2022
      RRID:CVCL_0027

      DOI: 10.1080/22311866.2021.1908162

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    4. scibot 18 Jun 2022
      RRID:CVCL_0027

      DOI: 10.1080/22311866.2021.1908162

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    52.53.155.43/8a1fc37683941d84eeb8b66103dbb7e364fe8145/Bergenin Attenuates Sodium Selenite Induced Hepatotoxicity via Improvement of Hepatic Oxidant Antioxidant Balance in HepG2 Cells and ICR Mice (3)-html.html
  31. www.sciencedirect.com www.sciencedirect.com
    A small-molecule Skp1 inhibitor elicits cell death by p53-dependent mechanism
    1
    1. scibot 25 Jun 2022
      RRID:CVCL_0027

      DOI: 10.1016/j.isci.2022.104591

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    sciencedirect.com/science/article/pii/S258900422200863X
  32. www.sciencedirect.com www.sciencedirect.com
    MacroH2As regulate enhancer-promoter contacts affecting enhancer activity and sensitivity to inflammatory cytokines
    1
    1. scibot 22 Jun 2022
      RRID:CVCL_0027

      DOI: 10.1016/j.celrep.2022.110988

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    sciencedirect.com/science/article/pii/S2211124722007744
  33. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    1. scibot 17 Jun 2022
      RRID:CVCL_0027

      DOI: 10.1111/bph.15863

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15863
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Metabolic-scale gene activation screens identify SLCO2B1 as a heme transporter that enhances cellular iron availability
    1
    1. scibot 17 Jun 2022
      ATCCHB-8065

      DOI: 10.1016/j.molcel.2022.05.024

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    pmc.ncbi.nlm.nih.gov/articles/PMC9356996/
  35. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Impact of non-coding RNAs on cancer directed immune therapies: Now then and forever
    1
    1. scibot 17 Jun 2022
      RRID:CVCL_0027

      DOI: 10.1002/ijc.34060

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    onlinelibrary.wiley.com/doi/10.1002/ijc.34060
  36. www.sciencedirect.com www.sciencedirect.com
    Active APPL1 sequestration by Plasmodium favors liver-stage development
    1
    1. scibot 03 Jun 2022
      RRID:CVCL_0027

      DOI: 10.1016/j.celrep.2022.110886

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    sciencedirect.com/science/article/pii/S2211124722006611
  37. www.sciencedirect.com www.sciencedirect.com
    Intracellular complement C5a/C5aR1 stabilizes β-catenin to promote colorectal tumorigenesis
    1
    1. scibot 02 Jun 2022
      ATCCCat#HB-8065

      DOI: 10.1016/j.celrep.2022.110851

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    sciencedirect.com/science/article/pii/S2211124722006246
  38. May 2022
  39. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial damage-associated molecular patterns trigger arginase-dependent lymphocyte immunoregulation
    1
    1. scibot 26 May 2022
      RRID:CVCL_0027

      DOI: 10.1016/j.celrep.2022.110847

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    sciencedirect.com/science/article/pii/S2211124722006209
  40. link.springer.com link.springer.com
    The V2 receptor antagonist tolvaptan counteracts proliferation and invasivity in human cancer cells
    1
    1. scibot 26 May 2022
      RRID:CVCL_0027

      DOI: 10.1007/s40618-022-01807-5

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    link.springer.com/article/10.1007/s40618-022-01807-5
  41. www.sciencedirect.com www.sciencedirect.com
    Upregulation of hepatic CD36 via glucocorticoid receptor activation contributes to dexamethasone-induced liver lipid metabolism disorder in mice
    1
    1. scibot 19 May 2022
      RRID:CVCL_0027

      DOI: 10.1016/j.toxlet.2022.05.003

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    sciencedirect.com/science/article/pii/S0378427422000911
  42. www.sciencedirect.com www.sciencedirect.com
    SETD4-mediated KU70 methylation suppresses apoptosis
    1
    1. scibot 11 May 2022
      ATCCCat#HB-8065

      DOI: 10.1016/j.celrep.2022.110794

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    sciencedirect.com/science/article/pii/S2211124722005617
  43. www.nature.com www.nature.com
    Convergent somatic mutations in metabolism genes in chronic liver disease
    1
    1. scibot 05 May 2022
      RRID:CVCL_0027

      DOI: 10.1038/s41586-021-03974-6

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    nature.com/articles/s41586-021-03974-6
  44. www.sciencedirect.com www.sciencedirect.com
    Glycine decarboxylase maintains mitochondrial protein lipoylation to support tumor growth
    1
    1. scibot 05 May 2022
      RRID:CVCL_0027

      DOI: 10.1016/j.cmet.2022.04.006

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    sciencedirect.com/science/article/pii/S1550413122001334
  45. f1000research.com f1000research.com
    <i>In vitro</i> and <i>in vivo</i> study: Ethanolic extract leaves of <i>Azadirachta indica</i> Juss. variant of Indonesia and Philippines suppresses tumor growth of hepatocellular carcinoma by inhibiting IL-6/STAT3 signaling
    1
    1. scibot 05 May 2022
      RRID:CVCL_0027

      DOI: 10.12688/f1000research.109557.1

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    f1000research.com/articles/11-477
  46. Apr 2022
  47. www.nature.com www.nature.com
    Blocked metabotropic glutamate receptor 5 enhances chemosensitivity in hepatocellular carcinoma and attenuates chemotoxicity in the normal liver by regulating DNA damage
    1
    1. scibot 30 Apr 2022
      RRID:CVCL_0027

      DOI: 10.1038/s41417-022-00465-2

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    nature.com/articles/s41417-022-00465-2
  48. link.springer.com link.springer.com
    Screening of candidate genes associated with high titer production of oncolytic measles virus based on systems biology approach
    1
    1. scibot 28 Apr 2022
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      DOI: 10.1007/s11262-022-01902-y

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  49. www.sciencedirect.com www.sciencedirect.com
    Cholesterol suppresses GOLM1-dependent selective autophagy of RTKs in hepatocellular carcinoma
    2
    1. scibot 21 Apr 2022
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      DOI: 10.1016/j.celrep.2022.110712

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  50. www.sciencedirect.com www.sciencedirect.com
    Lockdown, a selective small-molecule inhibitor of the integrin phosphatase PPM1F, blocks cancer cell invasion
    1
    1. scibot 21 Apr 2022
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      DOI: 10.1016/j.chembiol.2022.03.011

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  51. www.sciencedirect.com www.sciencedirect.com
    Interrogation of cancer gene dependencies reveals paralog interactions of autosome and sex chromosome-encoded genes
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  52. www.nature.com www.nature.com
    Transcriptome-wide identification of RNA-binding protein binding sites using seCLIP-seq
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  53. Mar 2022
  54. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Gene Expression Profiling of 1α,25(OH)2D3 Treatment in 2D/3D Human Hepatocyte Models Reveals CYP3A4 Induction but Minor Changes in Other Xenobiotic-Metabolizing Genes
    1
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  55. www.nature.com www.nature.com
    Symmetric and asymmetric receptor conformation continuum induced by a new insulin
    1
    1. scibot 23 Mar 2022
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      DOI: 10.1038/s41589-022-00981-0

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  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A survey of optimal strategy for signature-based drug repositioning and an application to liver cancer
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC8893721/
  57. www.sciencedirect.com www.sciencedirect.com
    Amelioration of hepatic steatosis by dietary essential amino acid-induced ubiquitination
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      DOI: 10.1016/j.molcel.2022.01.021

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  58. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A novel HSF1 activator ameliorates nonalcoholic steatohepatitis by stimulating mitochondrial adaptive oxidation
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      DOI: 10.1111/bph.15727

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  59. www.sciencedirect.com www.sciencedirect.com
    Establish an assessment model to characterized metastasis ability Single-cell multiomics reveals heterogeneous cell states linked to metastatic potential in liver cancer cell lines
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      DOI: 10.1016/j.isci.2022.103857

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  60. www.sciencedirect.com www.sciencedirect.com
    Isoform- and cell-state-specific lipidation of ApoE in astrocytes
    1
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  61. Feb 2022
  62. www.sciencedirect.com www.sciencedirect.com
    Protease-anti-protease compartmentalization in SARS-CoV-2 ARDS: Therapeutic implications
    1
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      DOI: 10.1016/j.ebiom.2022.103894

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  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A common variant in 11q23.3 associated with hyperlipidemia is mediated by the binding and regulation of GATA4
    1
    1. scibot 08 Feb 2022
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      DOI: 10.1038/s41525-021-00279-5

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  64. www.sciencedirect.com www.sciencedirect.com
    A macrophage-hepatocyte glucocorticoid receptor axis coordinates fasting ketogenesis
    1
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      ATTC HB-8065

      DOI: 10.1016/j.cmet.2022.01.004

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  65. onlinelibrary.wiley.com onlinelibrary.wiley.com
    ERα inhibits mesenchymal and amoeboidal movement of liver cancer cell via Gα12
    1
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      DOI: 10.1002/ijc.33929

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  66. www.sciencedirect.com www.sciencedirect.com
    SPARCLE, a p53-induced lncRNA, controls apoptosis after genotoxic stress by promoting PARP-1 cleavage
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      DOI: 10.1016/j.molcel.2022.01.001

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  67. Jan 2022
  68. www.sciencedirect.com www.sciencedirect.com
    The long noncoding RNA glycoLINC assembles a lower glycolytic metabolon to promote glycolysis
    1
    1. scibot 27 Jan 2022
      HB-8065

      DOI: 10.1016/j.molcel.2021.11.017

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  69. www.sciencedirect.com www.sciencedirect.com
    Macrophages activated by hepatitis B virus have distinct metabolic profiles and suppress the virus via IL-1β to downregulate PPARα and FOXO3
    1
    1. scibot 26 Jan 2022
      ATCCCat# HB-8065

      DOI: 10.1016/j.celrep.2021.110284

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  70. elifesciences.org elifesciences.org
    Hepatic MIR20B promotes nonalcoholic fatty liver disease by suppressing PPARA
    1
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      DOI: 10.7554/eLife.70472

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    elifesciences.org/articles/70472
  71. Dec 2021
  72. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    High-fat diet-induced increases in glucocorticoids contribute to the development of non-alcoholic fatty liver disease in mice
    1
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      DOI: 10.1096/fj.202101570R

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  73. www.nature.com www.nature.com
    Discovery of an exosite on the SOCS2-SH2 domain that enhances SH2 binding to phosphorylated ligands
    1
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  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Elevated FBXO45 promotes liver tumorigenesis through enhancing IGF2BP1 ubiquitination and subsequent PLK1 upregulation
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      DOI: 10.7554/eLife.70715

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  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The mesoscale organization of syntaxin 1A and SNAP25 is determined by SNARE–SNARE interactions
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  76. Nov 2021
  77. www.sciencedirect.com www.sciencedirect.com
    HRD1-mediated METTL14 degradation regulates m6A mRNA modification to suppress ER proteotoxic liver disease
    1
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      Cat# HB-8065

      DOI: 10.1016/j.molcel.2021.10.028

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  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Short-chain fatty acids activate acetyltransferase p300
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  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Enhanced Antitumor Effect in Liver Cancer by Amino Acid Depletion-Induced Oxidative Stress
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      DOI: 10.3389/fonc.2021.758549

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  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A sex-specific evolutionary interaction between ADCY9 and CETP
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      DOI: 10.7554/eLife.69198

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  81. academic.oup.com academic.oup.com
    GNA14’s interaction with RACK1 inhibits Hepatocellular Carcinoma progression through reducing MAPK/JNK and PI3K/AKT signaling pathway
    1
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      RRID:CVCL_0027

      DOI: 10.1093/carcin/bgab098

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    academic.oup.com/carcin/article/42/11/1357/6398702
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TAZ inhibits glucocorticoid receptor and coordinates hepatic glucose homeostasis in normal physiological states
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  83. Oct 2021
  84. www.sciencedirect.com www.sciencedirect.com
    Inhibition of glucose transport synergizes with chemical or genetic disruption of mitochondrial metabolism and suppresses TCA cycle-deficient tumors
    1
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  85. www.sciencedirect.com www.sciencedirect.com
    Glycogen accumulation and phase separation drives liver tumor initiation
    1
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  86. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      DOI: 10.1111/bph.15616

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  87. www.sciencedirect.com www.sciencedirect.com
    Homocysteine inhibits pro-insulin receptor cleavage and causes insulin resistance via protein cysteine-homocysteinylation
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      HB-8065

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  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NRF2 Dysregulation in Hepatocellular Carcinoma and Ischemia: A Cohort Study and Laboratory Investigation
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      DOI: 10.1148/radiol.2020200201

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  89. Sep 2021
  90. www.sciencedirect.com www.sciencedirect.com
    Lrp1 is a host entry factor for Rift Valley fever virus
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  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Long Noncoding RNA AC007639.1 Promotes the Pathogenesis and Progression of Hepatocellular Carcinoma Through Inhibiting Apoptosis and Stimulating Chemotherapeutic Resistance
    1
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      CVCL_0027

      DOI: 10.3389/fonc.2021.715541

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  92. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Genetically Encoded Protein Thermometer Enables Precise Electrothermal Control of Transgene Expression
    1
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    onlinelibrary.wiley.com/doi/10.1002/advs.202101813
  93. www.sciencedirect.com www.sciencedirect.com
    Controlled lipid β-oxidation and carnitine biosynthesis by a vitamin D metabolite
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      DOI: 10.1016/j.chembiol.2021.08.008

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  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Serjanic Acid Glycosides from Chenopodium hybridum L. with Good Cytotoxicity and Selectivity Profile against Several Panels of Human Cancer Cell Lines
    1
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      ATCC HB-8065

      DOI: 10.3390/molecules26164915

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  95. www.sciencedirect.com www.sciencedirect.com
    High-grade serous ovarian tumor cells modulate NK cell function to create an immune-tolerant microenvironment
    1
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  96. Aug 2021
  97. onlinelibrary.wiley.com onlinelibrary.wiley.com
    FNDC4 acts as an extracellular factor to promote the invasiveness of hepatocellular carcinoma partly via the PI3K/Akt signalling pathway
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      DOI: 10.1002/cam4.4225

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  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Application of human liver organoids as a patient-derived primary model for HBV infection and related hepatocellular carcinoma
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      DOI: 10.7554/eLife.60747

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  99. www.sciencedirect.com www.sciencedirect.com
    Loss of tyrosine catabolic enzyme HPD promotes glutamine anaplerosis through mTOR signaling in liver cancer
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      RRID: CVCL_0027

      DOI: 10.1016/j.celrep.2021.109617

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  100. 52.53.155.43 52.53.155.43
    v17p3595-html.html
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      DOI: 10.7150/ijbs.62471

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  101. link.springer.com link.springer.com
    Combinatorial antitumor effects of amino acids and epigenetic modulations in hepatocellular carcinoma cell lines
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      DOI: 10.1007/s00210-021-02140-z

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  102. www.nature.com www.nature.com
    Chemical tools for epichaperome-mediated interactome dysfunctions of the central nervous system
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      DOI: 10.1038/s41467-021-24821-2

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  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Towards novel herbicide modes of action by inhibiting lysine biosynthesis in plants
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  104. pubs.acs.org pubs.acs.org
    Regulation on Citrate Influx and Metabolism through Inhibiting SLC13A5 and ACLY: A Novel Mechanism Mediating the Therapeutic Effects of Curcumin on NAFLD
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      DOI: 10.1021/acs.jafc.1c03105

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  105. pubs.acs.org pubs.acs.org
    N-Methyl-4-phenylpyridinium Scaffold-Containing Lipophilic Compounds Are Potent Complex I Inhibitors and Selective Dopaminergic Toxins
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      DOI: 10.1021/acschemneuro.9b00184

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  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HNRNPM controls circRNA biogenesis and splicing fidelity to sustain cancer cell fitness
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  108. www.sciencedirect.com www.sciencedirect.com
    Feedback repression of PPARα signaling by Let-7 microRNA
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    ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency
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    Exocyst protein subnetworks integrate Hippo and mTOR signaling to promote virus detection and cancer
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      HB-8065

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    Measuring CPT-1-mediated respiration in permeabilized cells and isolated mitochondria
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  116. peerj.com peerj.com
    Heatstroke-induced hepatocyte exosomes promote liver injury by activating the NOD-like receptor signaling pathway in mice
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      DOI: 10.7717/peerj.8216

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    Macrophages-induced Long noncoding RNA H19 Up-regulation Triggers and Activates the miR-193b/MAPK1 Axis and Promotes Cell Aggressiveness in Hepatocellular Carcinoma
    1
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      RRID:CVCL_0027

      DOI: 10.1016/j.canlet.2019.11.001

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  118. Jul 2021
  119. www.sciencedirect.com www.sciencedirect.com
    Overcoming Fungal Echinocandin Resistance through Inhibition of the Non-essential Stress Kinase Yck2
    1
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      HEPG2

      DOI: 10.1016/j.chembiol.2019.12.008

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    Lipid Droplet-Derived Monounsaturated Fatty Acids Traffic via PLIN5 to Allosterically Activate SIRT1
    1
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      HepG2

      DOI: 10.1016/j.molcel.2019.12.003

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    Type-I-IFN-Stimulated Gene TRIM5γ Inhibits HBV Replication by Promoting HBx Degradation
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      HepG2

      DOI: 10.1016/j.celrep.2019.11.041

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    Neutralization of Oxidized Phospholipids Ameliorates Non-alcoholic Steatohepatitis
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      HepG2 cells

      DOI: 10.1016/j.cmet.2019.10.014

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  123. www.sciencedirect.com www.sciencedirect.com
    The Cancer SENESCopedia: A delineation of cancer cell senescence
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  124. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Betulinic acid alleviates endoplasmic reticulum stress‐mediated nonalcoholic fatty liver disease through activation of farnesoid X receptors in mice
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      RRID:CVCL_0027

      DOI: 10.1111/bph.14570

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  125. www.sciencedirect.com www.sciencedirect.com
    KDM3A Senses Oxygen Availability to Regulate PGC-1α-Mediated Mitochondrial Biogenesis
    1
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      Human: HepG2

      DOI: 10.1016/j.molcel.2019.09.019

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  126. www.sciencedirect.com www.sciencedirect.com
    AUTACs: Cargo-Specific Degraders Using Selective Autophagy
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      HepG2

      DOI: 10.1016/j.molcel.2019.09.009

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    Phosphoethanolamine Accumulation Protects Cancer Cells under Glutamine Starvation through Downregulation of PCYT2
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      HepG2

      DOI: 10.1016/j.celrep.2019.08.087

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  128. www.sciencedirect.com www.sciencedirect.com
    Glutarylation of Histone H4 Lysine 91 Regulates Chromatin Dynamics
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      HepG2

      DOI: 10.1016/j.molcel.2019.08.018

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  129. www.sciencedirect.com www.sciencedirect.com
    Trimethylamine N-Oxide Binds and Activates PERK to Promote Metabolic Dysfunction
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      HepG2

      DOI: 10.1016/j.cmet.2019.08.021

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    The Nuclear Matrix Protein SAFA Surveils Viral RNA and Facilitates Immunity by Activating Antiviral Enhancers and Super-enhancers
    1
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      Human:HepG2

      DOI: 10.1016/j.chom.2019.08.010

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    Targeting the N Terminus of eIF4AI for Inhibition of Its Catalytic Recycling
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      HepG2

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    GPR146 Deficiency Protects against Hypercholesterolemia and Atherosclerosis
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      RRID: CVCL_0027

      DOI: 10.1016/j.cell.2019.10.034

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    Hepatocytes Delete Regulatory T Cells by Enclysis, a CD4+ T Cell Engulfment Process
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    The TGFB2-AS1 lncRNA Regulates TGF-β Signaling by Modulating Corepressor Activity
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      DOI: 10.1016/j.celrep.2019.08.028

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    Glutamate Signaling in Hepatic Stellate Cells Drives Alcoholic Steatosis
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      Human: HepG2 cells

      DOI: 10.1016/j.cmet.2019.08.001

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  136. www.cell.com www.cell.com
    Pervasive Chromatin-RNA Binding Protein Interactions Enable RNA-Based Regulation of Transcription
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      Human: HepG2 cells

      DOI: 10.1016/j.cell.2019.06.001

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    OLFR734 Mediates Glucose Metabolism as a Receptor of Asprosin
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      HepG2

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  138. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  139. www.sciencedirect.com www.sciencedirect.com
    Multisite Phosphorylation of S6K1 Directs a Kinase Phospho-code that Determines Substrate Selection
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      DOI: 10.1016/j.molcel.2018.11.017

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  140. elifesciences.org elifesciences.org
    The packing density of a supramolecular membrane protein cluster is controlled by cytoplasmic interactions
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    Perturbation of Iron Metabolism by Cisplatin through Inhibition of Iron Regulatory Protein 2
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  142. link.springer.com link.springer.com
    Upregulation of microRNA-372 associates with tumor progression and prognosis in hepatocellular carcinoma
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      HepG2

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  143. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Impact of intracellular glyceraldehyde-derived advanced glycation end-products on human hepatocyte cell death
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      85011430

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  144. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sporadic PCDH18 somatic mutations in EpCAM-positive hepatocellular carcinoma
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    TGF-β signalling and PEG10 are mutually exclusive and inhibitory in chondrosarcoma cells
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    Survival Motor Neuron Protein is Released from Cells in Exosomes: A Potential Biomarker for Spinal Muscular Atrophy
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    Tumour-derived PGD2 and NKp30-B7H6 engagement drives an immunosuppressive ILC2-MDSC axis
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    Discovery and Development of TMPRSS6 Inhibitors Modulating Hepcidin Levels in Human Hepatocytes
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    ASN007 is a selective ERK1/2 inhibitor with preferential activity against RAS-and RAF-mutant tumors
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  150. www.nature.com www.nature.com
    3-hydroxyanthranic acid increases the sensitivity of hepatocellular carcinoma to sorafenib by decreasing tumor cell stemness
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    SREBP-1c impairs ULK1 sulfhydration-mediated autophagic flux to promote hepatic steatosis in high-fat-diet-fed mice
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    Establishment of live-cell-based coupled assay system for identification of compounds to modulate metabolic activities of cells
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  153. Jun 2021
  154. cancerres.aacrjournals.org cancerres.aacrjournals.org
    Stomatin-Mediated Inhibition of the Akt Signaling Axis Suppresses Tumor Growth
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    Identification of a Glypican-3 Binding Peptide From a Phage-Displayed Peptide Library for PET Imaging of Hepatocellular Carcinoma
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    CPSF4 regulates circRNA formation and microRNA mediated gene silencing in hepatocellular carcinoma
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    Probing low-copy-number proteins in single living cells using single-cell plasmonic immunosandwich assays
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  158. elifesciences.org elifesciences.org
    PHAROH lncRNA regulates Myc translation in hepatocellular carcinoma via sequestering TIAR
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  159. May 2021
  160. www.sciencedirect.com www.sciencedirect.com
    The autophagy protein Becn1 improves insulin sensitivity by promoting adiponectin secretion via exocyst binding
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    Systemic administration of monovalent follistatin-like 3-Fc-fusion protein increases muscle mass in mice
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    Histone deacetylase inhibitor resminostat in combination with sorafenib counteracts platelet-mediated pro-tumoral effects in hepatocellular carcinoma
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    Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis
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      RRID:CVCL_0027

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    Tandem Deubiquitination and Acetylation of SPRTN Promotes DNA-Protein Crosslink Repair and Protects against Aging
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    Hepatoprotective effects of ZLY16, a dual peroxisome proliferator-activated receptor α/δ agonist, in rodent model of nonalcoholic steatohepatitis
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    Centrosomal Localization of RXRα Promotes PLK1 Activation and Mitotic Progression and Constitutes a Tumor Vulnerability
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    Malic enzyme 2 connects the Krebs cycle intermediate fumarate to mitochondrial biogenesis
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  169. Apr 2021
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    Apaf-1 Pyroptosome Senses Mitochondrial Permeability Transition
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    Receptor-Mediated ER Export of Lipoproteins Controls Lipid Homeostasis in Mice and Humans
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    Gene editing and synthetically accessible inhibitors reveal role for TPC2 in HCC cell proliferation and tumor growth
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    Identification and characterization of novel splice variants of human farnesoid X receptor
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    Pharmacoproteomics Identifies Kinase Pathways that Drive the Epithelial-Mesenchymal Transition and Drug Resistance in Hepatocellular Carcinoma
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    Dipyridamole Inhibits Lipogenic Gene Expression by Retaining SCAP-SREBP in the Endoplasmic Reticulum
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  176. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The kynurenine derivative 3-HAA sensitizes hepatocellular carcinoma to sorafenib by upregulating phosphatases
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    Self-Reporting Transposons Enable Simultaneous Readout of Gene Expression and Transcription Factor Binding in Single Cells
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    PKCλ/ι Loss Induces Autophagy, Oxidative Phosphorylation, and NRF2 to Promote Liver Cancer Progression
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    DNAJC5 promotes hepatocellular carcinoma cells proliferation though regulating SKP2 mediated p27 degradation
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  180. www.mdpi.com www.mdpi.com
    Protein Binding Partners of Dysregulated miRNAs in Parkinson’s Disease Serum
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  181. www.sciencedirect.com www.sciencedirect.com
    The tissue protective functions of interleukin-22 can be decoupled from pro-inflammatory actions through structure-based design
    1
    1. scibot 14 Apr 2021
      HB-8065

      DOI: 10.1016/j.immuni.2021.03.008

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  182. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Blockade of AMPK-Mediated cAMP–PKA–CREB/ATF1 Signaling Synergizes with Aspirin to Inhibit Hepatocellular Carcinoma
    1
    1. scibot 13 Apr 2021
      RRID:CVCL_0027

      DOI: 10.3390/cancers13071738

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    ncbi.nlm.nih.gov/pmc/articles/PMC8038809/
  183. Mar 2021
  184. www.sciencedirect.com www.sciencedirect.com
    Metabolomic analysis of a selective ABCA1 inducer in obesogenic challenge provides a rationale for therapeutic development
    1
    1. scibot 27 Mar 2021
      RRID:CVCL_0027

      DOI: 10.1016/j.ebiom.2021.103287

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    sciencedirect.com/science/article/pii/S2352396421000803
  185. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    3-Methyladenine-enhanced susceptibility to sorafenib in hepatocellular carcinoma cells by inhibiting autophagy
    1
    1. scibot 20 Mar 2021
      RRID:CVCL_0027

      DOI: 10.1097/CAD.0000000000001032

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    ncbi.nlm.nih.gov/pmc/articles/PMC7952045/
  186. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Development of a novel, fully human, anti-PCSK9 antibody with potent hypolipidemic activity by utilizing phage display-based strategy
    1
    1. scibot 17 Mar 2021
      RRID:CVCL_0027

      DOI: 10.1016/j.ebiom.2021.103250

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    ncbi.nlm.nih.gov/pmc/articles/PMC7921758/
  187. www.sciencedirect.com www.sciencedirect.com
    Translational adaptation of human viruses to the tissues they infect
    1
    1. scibot 17 Mar 2021
      RRID:CVCL_0027

      DOI: 10.1016/j.celrep.2021.108872

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  188. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 03 Mar 2021
      RRID:CVCL_0027

      DOI: 10.1111/bph.15387

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15387
  189. Feb 2021
  190. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    1. scibot 28 Feb 2021
      RRID:CVCL_0027

      DOI: 10.1111/bph.15350

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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.15350
  191. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Hypoxia as a modulator of cytochromes P450: Overexpression of the cytochromes CYP2S1 and CYP24A1 in human liver cancer cells in hypoxia
    1
    1. scibot 27 Feb 2021
      RRID:CVCL_0027

      DOI: 10.1002/cbf.3612

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    onlinelibrary.wiley.com/doi/10.1002/cbf.3612
  192. www.sciencedirect.com www.sciencedirect.com
    Constitutive androstane receptor induced-hepatomegaly is partially via yes-associated protein activation
    1
    1. scibot 27 Feb 2021
      RRID:CVCL_0027

      DOI: 10.1016/j.apsb.2020.11.021

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    sciencedirect.com/science/article/pii/S2211383520308182
  193. pubs.acs.org pubs.acs.org
    Theaflavin TF3 relieves hepatocyte lipid deposition through activating AMPK signaling pathway by targeting plasma kallikrein
    1
    1. scibot 25 Feb 2021
      RRID:CVCL_0027

      DOI: 10.1021/acs.jafc.0c00148

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    pubs.acs.org/doi/full/10.1021/acs.jafc.0c00148
  194. www.nature.com www.nature.com
    NOD2 inhibits tumorigenesis and increases chemosensitivity of hepatocellular carcinoma by targeting AMPK pathway
    1
    1. scibot 24 Feb 2021
      RRID:CVCL_0027

      DOI: 10.1038/s41419-020-2368-5

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    nature.com/articles/s41419-020-2368-5
  195. elifesciences.org elifesciences.org
    Principles of dengue virus evolvability derived from genotype-fitness maps in human and mosquito cells
    1
    1. scibot 24 Feb 2021
      RRID:CVCL_0027

      DOI: 10.7554/eLife.61921

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    elifesciences.org/articles/61921
  196. www.frontiersin.org www.frontiersin.org
    Inhibition of Lipid Accumulation in Skeletal Muscle and Liver Cells: A Protective Mechanism of Bilirubin Against Diabetes Mellitus Type 2
    1
    1. scibot 11 Feb 2021
      RRID:CVCL_0027

      DOI: 10.3389/fphar.2020.636533

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    frontiersin.org/article/10.3389/fphar.2020.636533/full
  197. Jan 2021
  198. www.jneurosci.org www.jneurosci.org
    Golgi-Dependent Copper Homeostasis Sustains Synaptic Development and Mitochondrial Content
    1
    1. scibot 29 Jan 2021
      RRID:CVCL_0027

      DOI: 10.1523/JNEUROSCI.1284-20.2020

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    jneurosci.org/content/41/2/215
  199. link.springer.com link.springer.com
    Elevated levels of expression of cytochrome P450 3A4 in a human liver epithelial cell line in differentiation-inducing conditions
    1
    1. scibot 28 Jan 2021
      RRID:CVCL_0027

      DOI: 10.1007/s13577-021-00487-2

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    link.springer.com/article/10.1007/s13577-021-00487-2
  200. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The RNA-binding protein SFPQ preserves long-intron splicing and regulates circRNA biogenesis in mammals
    1
    1. scibot 28 Jan 2021
      RRID:CVCL_0027

      DOI: 10.7554/eLife.63088

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    ncbi.nlm.nih.gov/pmc/articles/PMC7819710/
  201. www.sciencedirect.com www.sciencedirect.com
    Genome-wide CRISPR-Cas9 knockout library screening identified PTPMT1 in cardiolipin synthesis is crucial to survival in hypoxia in liver cancer
    1
    1. scibot 27 Jan 2021
      RRID: CVCL_0027

      DOI: 10.1016/j.celrep.2020.108676

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    sciencedirect.com/science/article/pii/S221112472031665X
  202. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Torsin ATPases influence chromatin interaction of the Torsin regulator LAP1
    1
    1. scibot 06 Jan 2021
      RRID:CVCL_0027

      DOI: 10.7554/eLife.63614

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    ncbi.nlm.nih.gov/pmc/articles/PMC7773337/
  203. Dec 2020
  204. www.nature.com www.nature.com
    Composable microfluidic spinning platforms for facile production of biomimetic perfusable hydrogel microtubes
    1
    1. scibot 25 Dec 2020
      RRID:CVCL_0027

      DOI: 10.1038/s41596-020-00442-9

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    nature.com/articles/s41596-020-00442-9
  205. www.sciencedirect.com www.sciencedirect.com
    Autosomal Dominant Diabetes Associated with a Novel ZYG11A Mutation Resulting in Cell Cycle Arrest in Beta-Cells
    1
    1. scibot 20 Dec 2020
      RRID:CVCL_0027

      DOI: 10.1016/j.mce.2020.111126

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    sciencedirect.com/science/article/pii/S0303720720304287
  206. www.sciencedirect.com www.sciencedirect.com
    HCAR1/MCT1 Regulates Tumor Ferroptosis through the Lactate-Mediated AMPK-SCD1 Activity and Its Therapeutic Implications
    1
    1. scibot 13 Dec 2020
      HepG2

      DOI: 10.1016/j.celrep.2020.108487

      Resource: (KCLB Cat# 88065, RRID:CVCL_0027)

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    sciencedirect.com/science/article/pii/S2211124720314765
  207. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bioinformatic analysis and in vitro validation of a five-microRNA signature as a prognostic biomarker of hepatocellular carcinoma
    1
    1. scibot 13 Dec 2020
      RRID:CVCL_0027

      DOI: 10.21037/atm-20-2509

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    ncbi.nlm.nih.gov/pmc/articles/PMC7723630/
  208. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modular assembly–based approach of loosely packing co-cultured hepatic tissue elements with endothelialization for liver tissue engineering
    1
    1. scibot 12 Dec 2020
      RRID:CVCL_0027

      DOI: 10.21037/atm-20-1598

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    ncbi.nlm.nih.gov/pmc/articles/PMC7723527/
  209. www.authorea.com www.authorea.com
    Estrogen receptor alpha inhibits mesenchymal and amoeboidal movement of liver cancer cell via G protein subunit alpha 12
    1
    1. scibot 07 Dec 2020
      RRID:CVCL_0027

      DOI: 10.22541/au.160624514.40941389/v1

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    authorea.com/users/378507/articles/494981-estrogen-receptor-alpha-inhibits-mesenchymal-and-amoeboidal-movement-of-liver-cancer-cell-via-g-protein-subunit-alpha-12
  210. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BLOS1 mediates kinesin switch during endosomal recycling of LDL receptor
    1
    1. scibot 07 Dec 2020
      RRID:CVCL_0027

      DOI: 10.7554/eLife.58069

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    ncbi.nlm.nih.gov/pmc/articles/PMC7688313/
  211. Nov 2020
  212. onlinelibrary.wiley.com onlinelibrary.wiley.com
    S100 calcium‐binding protein A9 from tumor‐associated macrophage enhances cancer stem cell‐like properties of hepatocellular carcinoma
    1
    1. scibot 24 Nov 2020
      RRID: CVCL_0027

      DOI: 10.1002/ijc.33371

      Resource: (KCLB Cat# 88065, RRID:CVCL_0027)

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    onlinelibrary.wiley.com/doi/full/10.1002/ijc.33371
  213. portlandpress.com portlandpress.com
    Functional analysis of a species-specific inhibitor selective for human Na+-coupled citrate transporter (NaCT/SLC13A5/mINDY)
    1
    1. scibot 17 Nov 2020
      RRID:CVCL_0027

      DOI: 10.1042/BCJ20200592

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    portlandpress.com/biochemj/article/477/21/4149/226708/Functional-analysis-of-a-species-specific
  214. Oct 2020
  215. www.sciencedirect.com www.sciencedirect.com
    A Regulation Loop between YAP and NR4A1 Balances Cell Proliferation and Apoptosis
    1
    1. scibot 27 Oct 2020
      Hep-G2

      DOI: 10.1016/j.celrep.2020.108284

      Resource: (ATCC Cat# HB-8065, RRID:CVCL_0027)

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    sciencedirect.com/science/article/pii/S2211124720312730
  216. www.sciencedirect.com www.sciencedirect.com
    Tetracycline Antibiotics Induce Host-Dependent Disease Tolerance to Infection
    1
    1. scibot 20 Oct 2020
      Hep G2

      DOI: 10.1016/j.immuni.2020.09.011

      Resource: (ATCC Cat# HB-8065, RRID:CVCL_0027)

      Curator: @Naa003

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    sciencedirect.com/science/article/pii/S1074761320304052
  217. elifesciences.org elifesciences.org
    A powerful drug combination strategy targeting glutamine addiction for the treatment of human liver cancer
    1
    1. scibot 10 Oct 2020
      RRID:CVCL_0027

      DOI: 10.7554/eLife.56749

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    elifesciences.org/articles/56749
  218. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Increased dopamine and its receptor dopamine receptor D1 promote tumor growth in human hepatocellular carcinoma
    1
    1. scibot 10 Oct 2020
      CVCL_0027

      DOI: 10.1002/cac2.12103

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    onlinelibrary.wiley.com/doi/full/10.1002/cac2.12103
  219. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NFAT2 overexpression suppresses the malignancy of hepatocellular carcinoma through inducing Egr2 expression
    1
    1. scibot 10 Oct 2020
      RRID:CVCL_0027

      DOI: 10.1186/s12885-020-07474-0

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    ncbi.nlm.nih.gov/pmc/articles/PMC7542386/
  220. Sep 2020
  221. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Improving Scientific Rigor and Reproducibility: Check Research Resources Information When Planning Experiments Using dkNET
    1
    1. scibot 26 Sep 2020
      RRID:CVCL_0027

      DOI: 10.1096/fasebj.2020.34.s1.04748

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    faseb.onlinelibrary.wiley.com/doi/abs/10.1096/fasebj.2020.34.s1.04748
  222. www.nature.com www.nature.com
    The innate immune effector ISG12a promotes cancer immunity by suppressing the canonical Wnt/β-catenin signaling pathway
    1
    1. scibot 26 Sep 2020
      RRID:CVCL_0027

      DOI: 10.1038/s41423-020-00549-9

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    nature.com/articles/s41423-020-00549-9