1,177 Matching Annotations
  1. Oct 2025
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Antineoplastic Activity of a Novel Trispecific Single-Chain Antibody Targeting the hERG1/β1 Integrin Complex and TRAIL Receptors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12485380/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Telomeres control human telomerase (TERT) expression through non-telomeric TRF2
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    pmc.ncbi.nlm.nih.gov/articles/PMC12483519/
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    USP9X is a mechanosensitive deubiquitinase that controls tumor cell invasiveness and drug response through YAP stabilization
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    sciencedirect.com/science/article/pii/S221112472501143X
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    DUSP14 suppresses ferroptosis and promotes tumor progression of triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2211124725011362
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    Inter- and intra-tumoral ALDH1 heterogeneity in breast cancer identifies therapeutic opportunities for ALDH1A-specific inhibitors
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    sciencedirect.com/science/article/pii/S2451945625002685
  7. Sep 2025
  8. journals.sagepub.com journals.sagepub.com
    CAMSAP3 Suppresses Breast Cancer Metastasis and Serves as an Independent Prognostic Marker
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    journals.sagepub.com/doi/full/10.1177/15330338251381866
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CAMSAP3 Suppresses Breast Cancer Metastasis and Serves as an Independent Prognostic Marker
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    pmc.ncbi.nlm.nih.gov/articles/PMC12457760/
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Enhancing the in vitro anticancer efficacy of Paclitaxel against triple-negative breast cancer via an exopolysaccharide from a haloalkaliphilic archaeal strain
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    pmc.ncbi.nlm.nih.gov/articles/PMC12457646/
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    Engineering unnatural amino acids in peptide linkers enables cathepsin-selective antibody-drug conjugates for HER2-positive breast cancer
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    sciencedirect.com/science/article/pii/S0168365925008818
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    HEBP2-governed glutamine competition between tumor and macrophages dictates immunotherapy efficacy in triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S1550413125003821
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    Drug screening in 3D microtumors reveals DDR1/2-MAPK12-GLI1 as a vulnerability in cancer-associated fibroblasts
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    sciencedirect.com/science/article/pii/S2666379125004306
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    Loss of estrogen receptor alpha promotes distant metastasis through epithelial-mesenchymal transition in luminal-type breast cancer
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    sciencedirect.com/science/article/pii/S092544392500403X
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    PDE7A inhibition suppresses triple-negative breast cancer by attenuating de novo pyrimidine biosynthesis
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    sciencedirect.com/science/article/pii/S266637912500429X
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    Myosin-actin pattern links matrix stiffness to GFAT2-hyaluronan metabolism
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    sciencedirect.com/science/article/pii/S2590006425008750
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    Connexin 43 drives glioblastoma cancer stem cell phenotypes through a WNK lysine-deficient protein kinase 1-c-MYC signaling axis
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    sciencedirect.com/science/article/pii/S2211124725010745
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    A rapid imaging-based screen for induced-proximity degraders identifies a potent degrader of oncoprotein SKP2
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    nature.com/articles/s41587-025-02793-8
  19. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225018310-main-html.html
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    Tumor-Tissue Boundaries as Instructive Interfaces in Breast Cancer Cell Invasion
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202509249
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    Hispidulin Inhibits Metastasis of Triple Negative Breast Cancer by Promoting MDM2-mediated Apelin Degradation
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    authorea.com/users/962058/articles/1331009-hispidulin-inhibits-metastasis-of-triple-negative-breast-cancer-by-promoting-mdm2-mediated-apelin-degradation
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    Anticancer effects of 6-diazo-5-oxo-L-norleucine (DON)-loaded PLGA nanoparticles in triple-negative breast cancer by inhibiting glutamine metabolism: An integrated bioinformatic and experimental approach
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    sciencedirect.com/science/article/pii/S1773224725009025
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    Digital quantification of EV proteins and miRNAs enables early cancer diagnosis with 10 μL of plasma
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    Strategic Timing of Gene Silencing: Cellular Kinetics-Based Administration of siRNA for Optimized Photothermal Cancer Treatment
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202510802
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    USP18 Inhibition Enhances Type I Interferon Signalling and Immune Activation in the Tumour Microenvironment of Triple-Negative Breast Cancer
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    biorxiv.org/content/10.1101/2025.09.01.672152v1
  27. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Targeted Reprogramming of Tumor Cells by Digoxin-Loaded Immunogenic Nanoparticles Enhances Immunity Against Disseminated Tumor Cells
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    advanced.onlinelibrary.wiley.com/doi/10.1002/adhm.202502881
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mitochondrial glutathione import enables breast cancer metastasis via integrated stress response signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12396134/
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Novel Chimeric CTLA-4 B-cell Epitope Peptide Vaccines Demonstrate Effective Antitumor Immunity with/without PD1/PDL1 Blockade in Multiple Syngeneic Murine Models of Breast and Colorectal Cancers
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    pmc.ncbi.nlm.nih.gov/articles/PMC12402803/
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mucin 5AC promotes breast cancer brain metastasis through cMET/CD44v6
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    pmc.ncbi.nlm.nih.gov/articles/PMC11882111/
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Pan-RAS Inhibitor with a Unique Mechanism of Action Blocks Tumor Growth and Induces Antitumor Immunity in Gastrointestinal Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11875992/
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    Enzyme-mediated nanoreactors with cascade metabolic modulation for enhanced chemo-chemodynamic combination therapy
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    sciencedirect.com/science/article/pii/S0021979725023379
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    PKD3 localizes to late endosomes to maintain Rab7-dependent endolysosomal homeostasis
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    sciencedirect.com/science/article/pii/S2589004225016694
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    DNA-encoded library screening uncovers potent DNMT2 inhibitors targeting a cryptic allosteric binding site
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    pmc.ncbi.nlm.nih.gov/articles/PMC12396291/
  35. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Hypoxia-Induced PRMT1 Lactylation Drives Vimentin Arginine Asymmetric Dimethylation in Tumor Metastasis
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202509861
  36. Aug 2025
  37. www.sciencedirect.com www.sciencedirect.com
    NSUN2-mediated m5C hypermethylation of hsa_circ_0004516 promotes breast cancer brain metastasis by activating AKT signaling
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    sciencedirect.com/science/article/pii/S2468054025000976
  38. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Suppression of mTOR Signaling by miR-302/367 Cluster in Breast Cancer Cells
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202501582R
  39. www.tandfonline.com www.tandfonline.com
    EpCAM-targeted near-infrared photoimmunotherapy (NIR-PIT) for the treatment of breast cancer
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    tandfonline.com/doi/full/10.1080/07853890.2025.2540599
  40. www.biorxiv.org www.biorxiv.org
    Breast cancer cell migration is potentiated by associated fibroblasts through a laminin-511-Integrin α6β1-transduced Arp2/3 localization
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    biorxiv.org/content/10.1101/2025.08.10.669320v1
  41. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Programmable Nanodevice and Amplifier Module-Based DNA Cascaded Logic Circuits for Breast Tumor Cell Subtype Discrimination
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    advanced.onlinelibrary.wiley.com/doi/10.1002/adhm.202502784
  42. 52.53.155.43 52.53.155.43
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  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Preclinical Evaluation of DB-1419, a Novel Bifunctional and Bispecific Anti–B7-H3 × PD-L1 Antibody–Drug Conjugate
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    pmc.ncbi.nlm.nih.gov/articles/PMC12351279/
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    Inhibition of tumor cell macropinocytosis driver DHODH reverses immunosuppression and overcomes anti-PD1 resistance
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    sciencedirect.com/science/article/pii/S107476132500322X
  45. www.cell.com www.cell.com
    Small molecule dysregulation of ClpP activity via bidirectional allosteric pathways
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    cell.com/structure/abstract/S0969-2126(25)00261-8
  46. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Endogenous Fluorescence Labeling of Extracellular Vesicles with a Hydrophilic Cyanine Dye via Caveolin-1 Dependent Endocytosis
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/adhm.202502680
  47. www.biorxiv.org www.biorxiv.org
    CDK4 Restricts Triple-Negative Breast Cancer Cell Migration via Phosphorylation-Driven Activation of Myo9b RhoGAP Function
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    biorxiv.org/content/10.1101/2025.08.06.668850v1
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    53BP1 regulates p53-E2F7-dependent transcriptional gene repression and participates in the Fanconi anemia pathway
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    sciencedirect.com/science/article/pii/S2211124725009234
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    Building simplified cancer subtyping and prediction models with glycan gene signatures
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    sciencedirect.com/science/article/pii/S2667237525001766
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tissue-dependent mechanosensing by cells derived from human tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12328224/
  51. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    PD-L1-Targeting Biomimetic Photoresponsive Thermosensitive Liposomes for Triple-Negative Breast Cancer
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202506841
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    tiRNA: An Efficient and Controllable Gene Silencing Technology via Translation Inhibition
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    sciencedirect.com/science/article/pii/S1871678425000779
  53. 52.53.155.43 52.53.155.43
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  54. jitc.bmj.com jitc.bmj.com
    An affinity-modulated T cell engager targeting Claudin 18.2 shows potent anti-tumor activity with limited cytokine release
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    jitc.bmj.com/content/13/8/e011857
  55. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pathway metabolite ratios reveal distinctive glutamine metabolism in a subset of proliferating cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12322234/
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    IGM-7354, an Immunocytokine with IL15 Fused to an Anti–PD-L1 IgM, Induces NK and CD8+ T cell–Mediated Cytotoxicity of PD-L1–Positive Tumor Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12314523/
  57. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Azenosertib Is a Potent and Selective WEE1 Kinase Inhibitor with Broad Antitumor Activity Across a Range of Solid Tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12314526/
  58. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Four Amino Acid Intracellular Motif of VISTA Blocks Growth Receptor Signaling in Cancer Cells to Induce Tumor Suppression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12317733/
  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Combining Multiplexed CRISPR/Cas9-Nickase and PARP Inhibitors Efficiently and Precisely Targets Cancer Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12314522/
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    Aging-induced semaphorin 7a promotes TGF-β1-mediated cell plasticity and breast tumor metastases
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    sciencedirect.com/science/article/pii/S2211124725008137
  61. www.biorxiv.org www.biorxiv.org
    LeGO-Teknik reveals that the neurogenesis pathway is a clone-specific hallmark of brain metastasis in breast cancer
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    biorxiv.org/content/10.1101/2025.07.23.666035v1
  62. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    circEFR3A promotes breast cancer progression by sponging miR-590-3p to upregulate androgen receptor expression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12308457/
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    PALB2 and 53BP1 govern post-resection homologous recombination DNA repair
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    sciencedirect.com/science/article/pii/S1097276525006045
  64. Jul 2025
  65. www.sciencedirect.com www.sciencedirect.com
    Mesenchymal-epithelial transition reduces proliferation but increases immune evasion in tumor spheroids
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    Identification of CNOT1-CCR4-NOT as a suppressor of 53BP1-p53-p21 signaling
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    sciencedirect.com/science/article/pii/S2211124725008617
  67. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Anti-nociceptive action of leonurine through TRPA1 and TRPV4 channels modulation
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.70135
  68. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A hexamerization-enhanced, Fc-silenced agonistic CD27 antibody amplifies T-cell effector functions as single agent and in combination with PD-1 blockade
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    pmc.ncbi.nlm.nih.gov/articles/PMC12289993/
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    Dual Regulation of FZD1/7 by IGF2BP3 Enhances Stem-like Properties and Carboplatin Resistance in Triple-Negative Breast Cancer
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    sciencedirect.com/science/article/pii/S0304383525005130
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    Sophoridine inhibits proliferation and migration by targeting PIM1 in breast cancer
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    tandfonline.com/doi/abs/10.1080/13880209.2025.2537123
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    Tumor-specific CD8 T cell characterization in HR+ breast cancer reveals an impaired antitumoral response in patients with lymph node metastasis
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    MARCO expression on myeloid-derived suppressor cells is essential for their differentiation and immunosuppression
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  73. pubs.acs.org pubs.acs.org
    Novel Aptamer-Drug Conjugate for Targeted Therapy in Triple-Negative Breast Cancer
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    pubs.acs.org/doi/full/10.1021/acs.jmedchem.5c00492
  74. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MSN/STAT3 drives cancer stemness and chemoresistance via IL-6/LPAR1 ligand receptor complex in triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12281688/
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    MyoD is Essential in Rhabdomyosarcoma by Promoting Survival Through Differentiation and CYLD
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    Targeting Triple-Negative Breast Cancer with Momordicine-I for Therapeutic Gain in Preclinical Models
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    Nostoc commune-derived scytonemin induced mitochondrial cell death in leukemia models
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    Identifying the Impact of RelA Overexpression in Triple-Negative Breast Cancer Cells Using Mass Spectroscopy-based Proteomics and Metabolomics Analysis
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.202500717
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    Substitution of a proline residue in the frog skin host-defense peptide, figainin-2PL by D-lysine generates an analog with potent activity against antibiotic-resistant ESKAPE pathogens
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    Artificial intelligence-driven discovery of YH395A: A novel TGFβR1 inhibitor with potent anti-tumor activity against triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12235933/
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    A Rac-specific competitive inhibitor of guanine nucleotide binding reduces metastasis in triple-negative breast cancer
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    Covalent inhibition of ACSL4 alleviates ferroptosis-induced acute liver injury
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    Gallium maltolate and cisplatin co-treatment effectively targets triple-negative breast cancer in spheroid and mouse models
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