5,430 Matching Annotations
  1. Feb 2026
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    Proximity labeling of the Listeria monocytogenes surface reveals pathogen control of a host deubiquitinase
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    biorxiv.org/content/10.64898/2026.02.17.706400v1
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    KRASG12V/HLA-A*02:01–targeted chimeric antigen receptor T cells exhibit potent preclinical activity against solid tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12922744/
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    KRASG12V/HLA-A*02:01–targeted chimeric antigen receptor T cells exhibit potent preclinical activity against solid tumors
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    science.org/doi/10.1126/sciadv.aea2511
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    The FOSB-IGFBP5-IGF-1 axis: a novel regulatory pathway that suppresses prostate cancer growth
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    nature.com/articles/s41417-026-01012-z
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    pmc.ncbi.nlm.nih.gov/articles/PMC12972699/
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    Fasting impairs humoral immunological memory by β-hydroxybutyrate-mediated depletion of plasma cells
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    sciencedirect.com/science/article/pii/S1074761326000038
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    An Insulin-Exosome-TNFAIP8 Axis Drives Stromal Fibrosis and Therapeutic Resistance in Pancreatic Cancer
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    Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism
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    pmc.ncbi.nlm.nih.gov/articles/PMC7618758/
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    Functional rescue and AI analysis of a human inactivating GPCR mutation using a small molecule
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    The pyrin domain of IFI16 forms a distinct filament structure important for IFI16-mediated enhancement of STING activation
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    sciencedirect.com/science/article/pii/S0969212626000134
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    BRD4-mediated ER membrane contact creates functionally distinct mitochondrial subtypes
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    sciencedirect.com/science/article/pii/S1097276526000328
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    A GPX1-OSBPL8 axis mediates noncanonical in vivo ferroptosis and cancer growth suppression
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    Single-cell multi-omic analyses highlight the essential role of NKX2.2-CLEC16A/endosomal pathway for human pancreatic differentiation and function
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    Targeting the SIN1 mediated TTK/LDHA-H3K18la-GLUT3 Axis Disrupts Metabolic-Epigenetic Crosstalk and Suppresses Progression in Hyperglycolytic Breast Cancer
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    Impaired excitability of fast-spiking neurons in a novel mouse model of KCNC1 epileptic encephalopathy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12916103/
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    Differential regulation of translational stress responses by herpesvirus ubiquitin deconjugases
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    Native stem cell transcriptional circuits define cardinal features of high-risk leukemia
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    Guardian ubiquitin E3 ligases target cancer-associated APOBEC3 deaminases for degradation to promote human genome integrity
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    Prevention of transgene silencing during human pluripotent stem cell differentiation
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    sciencedirect.com/science/article/pii/S1934590926000305
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    Src-mediated PHB2 phosphorylation disrupts mitochondrial cristae through cardiolipin dissociation in hepatocellular carcinoma
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    A 3D multi-compartment assembloid to study combined immune cell infiltration and cytotoxicity
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    ACSL4-associated lipid metabolism is a distinct therapeutic vulnerability in KMT2A-rearranged acute myeloid leukemia
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    Small-molecule enhancement of METTL3 S-palmitoylation as a therapeutic strategy for osteoarthritis
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    Hepatocyte PLAGL2 deficiency alleviates MASH through MYD88-licensed inactivation of inflammasome
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    TAX1BP1 recruitment reactivates autophagy of Tau aggregates through ULK1 and TBK1
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    biorxiv.org/content/10.64898/2026.02.12.705532v1
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    pubs.acs.org/doi/10.1021/acsami.5c21141
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    An AIB1 isoform rewires glucocorticoid receptor signaling to promote TNBC progression
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    miR-940 suppresses ferroptosis by controlling expression of key regulatory genes
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    Multichannel genomic recording of biological information with ENGRAM
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    Juvenile-to-adult refinement of thalamic reticular circuits via LRRTM3 enables high-resolution sensory encoding
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    Non-invasive ovulation tracking enables genetic engineering in wild rodents
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    Glomerular basement membrane structural integrity dictates trans-tissue deposition of laminin in the kidney
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    Liver exerkine reverses aging- and Alzheimer’s-related memory loss via vasculature
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    Extracellular matrix sensing regulates intratumoral heterogeneity of autophagic flux
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    CD4 Mimic-Neutralizing Antibody Conjugates Synthesized by Site-Specific Modification Methods as HIV-1 Entry Inhibitors
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    chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/cmdc.202500820
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    TRIM40 Drives Pathological Cardiac Hypertrophy and Heart Failure via Ubiquitination of PKN2
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    Targeted Mitochondrial ECSIT Overexpression Attenuates MASH by Increasing OTUD3 Expression
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202518974
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    NuSAP Safeguards Centriole Integrity to Mediate CEP57-CEP152 Torus Recruitment for Proper Engagement
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    Effects of N361 Glycosylation on Epidermal Growth Factor Receptor Biological Function
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    CD8a antibody-functionalized biomimetic red blood cell membrane ectosomes delivering C646 reverse CD8⁺ T Cell exhaustion via H3K18la histone delactylation in gastric cardia adenocarcinoma
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    Therapeutic targeting of YOD1 disrupts the PAX-FOXO1-N-Myc feedback loop in rhabdomyosarcoma
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    Ablation of Tumor-Derived IGFBP-3 Attenuates Cancer-Associated Skeletal Muscle Wasting in Murine Pancreatic Cancer
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    Structural basis for late maturation steps of mitochondrial respiratory chain complex IV within the human respirasome
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    ZNF711 promotes enzalutamide resistance through transcriptional and epigenetic modification of the androgen receptor signaling pathway
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    Triglycerides induce endoplasmic reticulum lipid bilayer stress to activate PERK and enhance antifungal immunity
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    A CRISPR-based mitochondrial gene therapy tool derived by engineering guide RNAs
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    Tumor-immune-neural circuit disrupts energy homeostasis in cancer cachexia
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    SpeckSeq enables high-throughput functional stratification of MEFV variants in autoinflammatory diseases
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    CRM1 inhibits NPAT condensation and histone locus body formation via a competitive occupation strategy
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    The active secretion of a subunit of IL-12 by tissue cells is regulated by Valosin-Containing Protein and intracellular calcium redistribution
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    RAD51 succinylation regulates homologous recombination and contributes to the chemosensitivity in cancer
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    Functional characterization of CASP, a CUX1 isoform, reveals its tumor-promoting role in colorectal cancer via TRIM21-mediated signaling
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    An orthogonal CRISPR/Cpf1 platform for precise spatiotemporal gene regulation and osteoporotic fracture repair
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    SNAP25 undergoes phase separation to facilitate the assembly of the synaptic vesicle fusion machinery
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    Tfam-mediated metabolic perturbation in RORγt+ lymphocytes impacts intestinal tissue homeostasis and promotes GATA3+RORγt+ innate lymphoid cells
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    Humanization and engineering of protective antibodies targeting severe fever with thrombocytopenia syndrome virus Gn protein
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    Systematic cysteine scanning identifies a druggable pocket in oncogenic KRAS
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    Porcine IRF2 suppresses the cGAS-STING-mediated antiviral IFN signaling by competing IRF3 for binding to the IFN promoter
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    High-throughput ligand discovery in living cells using the cellular protein stability enhancement assay
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    Targeting CXADR-mediated AKT signaling suppresses tumorigenesis and enhances chemotherapy efficacy in Ewing sarcoma
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    Netrin-1 Promotes Pancreatic Tumorigenesis and Innervation through NEO1
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    Cullin-3 adaptor SHKBP1 inhibits SQSTM1/p62 oligomerization and Keap1 sequestration
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    Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription
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    A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
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    SERPINA3 mediates liver cancer cells escape from chemotherapy-induced neutrophil extracellular trap killing
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    The molecular and functional landscape of resistance to FOLFIRI chemotherapy in metastatic colorectal cancer
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    AMPK-mediated HCN4 channel phosphorylation contributes to age-related intrinsic bradycardia
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    RBPscan: A quantitative in vivo tool for profiling RNA-binding protein interactions
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    Keratinocyte Transport of Notoginsenoside R1 via ABCG2: A Novel Mechanism for RNA N6-Methyladenosine Modification in UVB Induced Skin Sunburn Injury
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    RB-BC: A Novel Ribociclib Derivative Targeting p53-Mediated Apoptosis and Inhibition of Tumor Growth in Breast Cancer
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    Repression of PRMT activities sensitize human homologous recombination-proficient ovarian and breast cancer cells to PARP inhibitor treatment
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    CaMKIIβ-mediated phosphorylation enhances protein stability of spastin to promote neurite outgrowth
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    Cell-free DNA epigenomic profiling enables noninvasive detection and monitoring of translocation renal cell carcinoma
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    FAM135B Deficiency Inhibits Cytotoxic T-cell Activity in Triple-Negative Breast Cancer by Blocking the IFI16-Dependent STING Pathway
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    Aquaporin‐1, aquaporin‐3 and aquaporin‐5 differentially modulate cell biophysical and biomechanical properties, impacting cell stiffness and cell–cell adhesion
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    Human Dorsal Root Ganglia Neuronal Cell Line to Study Nociceptive Signaling: A New Pipeline for Pain Therapy
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    Covalent modification of a glutamic acid inspired by HaloTag technology
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