5,649 Matching Annotations
  1. Apr 2026
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PTEN Loss Promotes PI3Kβ Phosphorylation and EPHA2/SRC/p-PI3KβY962 Complex Assembly to Drive Tumorigenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13056290/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mutational Signatures and Clonal Hematopoiesis in Intestinal Metaplasia across Countries with Varying Stomach Cancer Incidence
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    pmc.ncbi.nlm.nih.gov/articles/PMC13056296/
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MAPK Pathway Mutations Emerge in Mutant IDH1 Inhibitor–Resistant Cholangiocarcinoma and Attenuate the IFN Response
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    pmc.ncbi.nlm.nih.gov/articles/PMC13056288/
  5. 54.241.53.176 54.241.53.176
    Functionalizing hydrogel nanovials with vesicles mimicking antigen-presenting vesicles and cancer exosomes improves T cell capture and activation
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    54.241.53.176/f6aa408ab8e273f982a84b41e69ca3441364a930/2025.06.24.661128.full-html.html
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    A µ-opioid receptor superagonist analgesic with minimal adverse effects
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    nature.com/articles/s41586-026-10299-9
  7. www.nature.com www.nature.com
    X-linked cancer-associated polypeptide (XCP) from lncRNA1456 modulates PHF8 histone demethylase activity to regulate the epigenome, gene expression, and cellular pathways in breast cancer
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    nature.com/articles/s41388-026-03740-w
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    1-s2.0-S2589004226009788-main-html.html
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    sciencedirect.com/science/article/pii/S2589004226009788
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    Nonsense-mediated mRNA decay inhibition reshapes the cancer immunopeptidome
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    sciencedirect.com/science/article/pii/S1074761326000750
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    The AGPS regulatory variant rs113671272 confers esophageal squamous cell carcinoma susceptibility through allele-specific MEIS3 binding and NF-κB activation in Chinese populations
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    sciencedirect.com/science/article/pii/S2352396426001313
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    A nature-inspired nanoplatform for multi-protein targeted degradation via the autophagy-lysosome pathway
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    sciencedirect.com/science/article/pii/S2451945626000772
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    Ets1-dependent Mek-Erk signaling drives adipose tissue macrophage anti-inflammatory polarization to ameliorates insulin resistance
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    sciencedirect.com/science/article/pii/S2211124726003220
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    Gemella morbillorum Promotes Colorectal Carcinogenesis: LPBDCP-Mediated Invasion Activates Ras Signaling and Destabilizes p53
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202517245
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    Defining the functional role and potential as an immunotherapeutic target of ALCAM in neuroblastoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12729689/
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MIF-Induced CD74+ Microglia and Macrophages Promote Progression of Brain Metastasis and are Clinically Relevant Across Central Nervous System Disorders
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    pmc.ncbi.nlm.nih.gov/articles/PMC7618953/
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    PCSK9 promotes prostate cancer via facilitating intratumoral cholesterol accumulation and enhancing immunosuppressive tumor microenvironment
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    sciencedirect.com/science/article/pii/S2090123226002997
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    Rhein inhibits respiratory syncytial virus entry by stabilizing the prefusion conformation of the fusion protein
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    sciencedirect.com/science/article/pii/S2090123226002791
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    Targeting SERPINE1 enhances PD-1 blockade response by modulating macrophage infiltration and polarization through the STAT3-CCL2 axis in non-small cell lung cancer
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    sciencedirect.com/science/article/pii/S1567576926004224
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    Exome sequencing enables molecular diagnosis in 10% of early-onset or familial systemic lupus erythematosus cases
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    thelancet.com/journals/ebiom/article/PIIS2352-3964(26)00091-5/abstract
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    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/2211-5463.70224
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    PDIA6 promotes the cell proliferation of ESCC by enhancing the disulfide bond formation in TRAF4
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    pmc.ncbi.nlm.nih.gov/articles/PMC13041448/
  22. www.biorxiv.org www.biorxiv.org
    Actionable spatial prostanoid barriers constrain BiTE-driven adoptive T cell immunity in intact human tumors
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    biorxiv.org/content/10.64898/2026.03.26.713601v1
  23. aacrjournals.org aacrjournals.org
    Serotonin modulates lineage plasticity in neuroendocrine prostate cancer via epigenetic reprogramming
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    aacrjournals.org/cancerdiscovery/article/16/4/760/775565/Serotonin-Modulates-Lineage-Plasticity-in
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Acetylation-triggered degradation of MSX1 impairs palatal development
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    pmc.ncbi.nlm.nih.gov/articles/PMC13039415/
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    AURKA-mediated destabilization of SAPS3 drives ferroptosis evasion via 7-dehydrocholesterol biosynthesis in colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13039981/
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    Dual function of DOT1L suppresses tumor cell-intrinsic immunogenicity in hepatocellular carcinoma
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    nature.com/articles/s41388-026-03744-6
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Precision‐Engineered Silver Single‐Atom Carbon Dot Nanozymes for Theranostic Management of Acute Kidney Injury
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    pmc.ncbi.nlm.nih.gov/articles/PMC13042797/
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Structure‐Guided Engineering of a Cas12i Nuclease Unlocks Near‐PAMless Genome Editing
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    pmc.ncbi.nlm.nih.gov/articles/PMC13042403/
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Disordered Region of ASXL1 Acts as an Auto‐Regulator Through Condensation
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    pmc.ncbi.nlm.nih.gov/articles/PMC13042807/
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Comprehensive Profiling of N 6‐methyladnosine (m6A) Readouts Reveals Novel m6A Readers That Regulate Human Embryonic Stem Cell Differentiation
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    pmc.ncbi.nlm.nih.gov/articles/PMC13042514/
  31. www.biorxiv.org www.biorxiv.org
    Phosphorylation-driven Targeted Protein Degradation of Oncogenic β-catenin
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    biorxiv.org/content/10.64898/2026.03.16.712096v1
  32. aacrjournals.org aacrjournals.org
    Identification of Small-Molecule Inhibitors that Block the GTP-Binding Pocket of K-Ras and Other Members of the Ras Superfamily of Small GTPases
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    aacrjournals.org/mct/article/25/1/84/771280/Identification-of-Small-Molecule-Inhibitors-that
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    Human promoter-driven AAV tools enable precision gene therapy targeting cochlear hair cells
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    sciencedirect.com/science/article/pii/S2666379126001424
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    Assessing the suitability of deubiquitylases as substrates for targeted protein degradation
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    IAP-based biodegraders can convert necroptosis to apoptosis and eliminate cancer driving protein complexes
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    sciencedirect.com/science/article/pii/S2451945626000759
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    PTEN loss drives B7H3 upregulation via the mTORC2/FOXO/c-Myc axis to promote tumor immune escape in ovarian cancer
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    sciencedirect.com/science/article/pii/S2211124726002767
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    Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202521101
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    Combined inactivation of MEK and mTOR can lead to synergistic cell death in glioblastoma models and associates with NF1-deficiency and a mesenchymal subtype
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    aacrjournals.org/mct/article/24/12/1878/768319/Combined-Inactivation-of-MEK-and-mTOR-Can-Lead-to
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    Analysis of structure and conservation for supporting functional evaluation of PMS2 missense variants
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    nature.com/articles/s41431-026-02072-3
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    Lactylome Reprogramming Mediates Therapeutic Response and Adaptation to Neoadjuvant Chemotherapy in Esophageal Squamous Cell Carcinoma
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    sciencedirect.com/science/article/pii/S1535947626000575
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    Broad-spectrum coronavirus inhibition by RSV fusion inhibitors targeting six-helix bundle formation
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    sciencedirect.com/science/article/pii/S0024320526001669
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    Vesicle trafficking 1 in breast cancer tissue and serum orchestrates metastatic progression and an immunosuppressive microenvironment
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    sciencedirect.com/science/article/pii/S1567576926004091
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    EEPD1 Inhibition Unleashes Antitumor Immunity in Colorectal Cancer by Activating the cGAS-STING Pathway
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202522826
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    Glutamine Deprivation Triggers Tribbles Homolog 3 Dependent G-Quadruplex Resolution to Maintain DNA Repair and Tumor Survival
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202520798
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Precision-Engineered DC-Targeting mRNA-LNP Neoantigen Vaccine Elicits Stronger T Cell Responses and Exhibits Superior Tumor Control
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    pmc.ncbi.nlm.nih.gov/articles/PMC13030069/
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The aryl hydrocarbon receptor (AHR) drives human leukocyte antigen (HLA)-II expression in human melanoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13032475/
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of miR-29a/b1 cluster reprograms the tumor microenvironment and contributes to immunosuppression in lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13034170/
  49. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Hsa_circ_0000313/miR-1224-3p/MKNK2 Axis Modulates CD4+ T Cells by Activating p38 MAPK Signaling in Myasthenia Gravis
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    onlinelibrary.wiley.com/doi/10.1155/mi/2877539
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.70508
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.70490
  52. Mar 2026
  53. 54.241.53.176 54.241.53.176
    2026.03.19.713006.full-html.html
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    54.241.53.176/a51f1a6bf2490375150e451ee0099fc78172f3a7/2026.03.19.713006.full-html.html
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    Pre-existing cell states predict resistance to multiple treatments
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    sciencedirect.com/science/article/pii/S2666979X26000534
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    Host-transposon mutualism supports regeneration in planarians
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    sciencedirect.com/science/article/pii/S1534580726000870
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    Shear stress-induced Piezo1 activates CD99L2 to facilitate the initiation of blood circulation
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    sciencedirect.com/science/article/pii/S2211124726002780
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    Cars2-Mediated Cysteine Catabolism Drives Brown Fat Development and Thermogenesis Through Persulfidating EBF2
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202522690
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    Regulatory T cell-derived TGF-β signaling governs the differentiation and maintenance of tumor-infiltrating bystander CD8+ T cells
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    sciencedirect.com/science/article/pii/S2211124726002676
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    Evaluating the Utilities of Foundation Models in Single-Cell Data Analysis
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202514490
  60. www.nature.com www.nature.com
    Tracking-seq: a universal off-target detection approach for CRISPR–Cas genome editing
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    nature.com/articles/s41596-025-01331-9
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    Cell-type-focused compound screen in human organoids reveals CK1 inhibition protects cone photoreceptors from death
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    sciencedirect.com/science/article/pii/S0896627326001297
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    Polyglutamine homorepeat regulates Runx2 condensation and cellular localization in a KPNA3-dependent manner
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    sciencedirect.com/science/article/pii/S2211124726002834
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    STUB1-VCP/p97 complex regulates mitophagy via fine-tuning of PINK1 levels
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    A convergent uPAR-positive tumor ecosystem creates broad vulnerability to CAR T cell therapy
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    sciencedirect.com/science/article/pii/S0092867426002692
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    ETV4 Promotes Colorectal Cancer Progression by Reprogramming Asparagine Metabolism to Remodel the Stromal Microenvironment
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202516557
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    A Physiological Microfluidic Blood–Brain-Barrier Model for In Vitro Study of Nanoparticle Trafficking and Accumulation
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    advanced.onlinelibrary.wiley.com/doi/10.1002/adhm.202600019
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    UFMylation-dependent inhibition of AKT signaling by PHLDA3 in lung adenocarcinoma
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    sciencedirect.com/science/article/pii/S2211124726002329
  69. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Uev1A counteracts oncogenic Ras stimuli in both polyploid and diploid cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC13016607/
  70. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRISPR-Drug Combinatorial Screening Identifies Effective Combination Treatments for MTAP-deleted cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13014710/
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    Ceramide mediates cell-to-cell ER stress transmission by modulating membrane fluidity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11938942/
  72. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Protocol to generate immunocompetent human heart-macrophage assembloids for the study of immune-cardiac interactions
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    pmc.ncbi.nlm.nih.gov/articles/PMC12992950/
  73. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Direct interaction between human DDX1 and SARS-CoV-2 Nucleocapsid protein is regulated by phosphorylation
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    pmc.ncbi.nlm.nih.gov/articles/PMC13125193/
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    A cytomegalovirus-encoded lncRNA blocks cell-cycle progression
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    sciencedirect.com/science/article/pii/S1097276526001565
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    Receptor-ubiquitination-targeting antibody-drug conjugates for enhanced endocytosis and lysosomal delivery
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    STING signaling modulation by COPII cargo recognition
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    sciencedirect.com/science/article/pii/S0092867426002679
  77. link.springer.com link.springer.com
    TRIM4 modulates the ubiquitin-mediated degradation of hnRNPDL and weakens sensitivity to CDK4/6 inhibitor in ovarian cancer
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    link.springer.com/article/10.1007/s11684-024-1103-5
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    Adaptor protein supersaturation drives innate immune signaling and cell fate
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    pmc.ncbi.nlm.nih.gov/articles/PMC13012725/
  79. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TIPE2 knockdown enhances the anti-tumor efficacy of NKG2D CAR-T cells against pancreatic cancer via activating NF-κb signaling pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC13011749/
  80. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Nanobody-Engineered CLL-1 CAR-T Cells: Optimizing Tumor-Specific Cytotoxicity and Minimizing Off-Tumor Toxicity
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    pmc.ncbi.nlm.nih.gov/articles/PMC13012018/
  81. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Collagen-bearing exosomes from breast cancer-associated fibroblasts promote T cell dysfunction
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    pmc.ncbi.nlm.nih.gov/articles/PMC13012019/
  82. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Extracellular Vesicle-Mediated O-GlcNAcase Transfer Drives Neuronal Necroptosis to Facilitate Gallbladder Cancer Perineural Invasion
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    pmc.ncbi.nlm.nih.gov/articles/PMC13012253/
  83. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Integrative Multi-omic Classification Reveals Distinct Origins and Evolutionary Trajectories of Thymic Epithelial Tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC13012242/
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    A correlative workflow for synaptic imaging by cryo-electron tomography
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