543 Matching Annotations
  1. Oct 2025
  2. www.sciencedirect.com www.sciencedirect.com
    Local delivery of IL-15 and anti-PD-L1 nanobody by in vitro-transcribed circILNb elicits superior antitumor immunity in cold tumors
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    sciencedirect.com/science/article/pii/S2666379125004860
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    In situ extended immune activation instantly after tumor resection by oncolytic virus controls postoperative tumor recurrence
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    sciencedirect.com/science/article/pii/S2666379125004720
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    YEATS4 reads histone crotonylation to promote fatty acid metabolism and cancer cell stemness
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    sciencedirect.com/science/article/pii/S2211124725011714
  5. pubs.acs.org pubs.acs.org
    A Nitroreductase-Activated Chemiluminescent Prodrug for Real-Time Monitoring of Camptothecin Release in Peritoneal Metastasis Theranostics
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    pubs.acs.org/doi/full/10.1021/acs.jmedchem.5c01674
  6. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Synergistic Promotion of Triple-Negative Breast Cancer Tumorigenesis and Metastasis by Oral Polystyrene Nanoplastics Exposure via Alloprevotella-Derived Glutamate and Platelet Activation
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202508310
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    DEC1 promotes breast cancer bone metastasis through transcriptional activation of CXCR4
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    pmc.ncbi.nlm.nih.gov/articles/PMC12481698/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Depleting the Action of EZH2 through PI3K–mTOR Inhibition to Overcome Metastasis and Immunotherapy Resistance in Triple-Negative Breast Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12485387/
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    Inter- and intra-tumoral ALDH1 heterogeneity in breast cancer identifies therapeutic opportunities for ALDH1A-specific inhibitors
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    sciencedirect.com/science/article/pii/S2451945625002685
  10. Sep 2025
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    Drug screening in 3D microtumors reveals DDR1/2-MAPK12-GLI1 as a vulnerability in cancer-associated fibroblasts
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    sciencedirect.com/science/article/pii/S2666379125004306
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Vascular heterogeneity of tight junction Claudins guides organotropic metastasis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11987010/
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    Protocol for isolation and flow cytometric analysis of interstitial macrophages in murine lung metastasis models
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    sciencedirect.com/science/article/pii/S2666166725004666
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    Dual STING activation and CD47/SIRPα blockade via chitooligosaccharide-based nanoparticles to amplify antitumor immunity
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    sciencedirect.com/science/article/pii/S0168365925008478
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    Hispidulin Inhibits Metastasis of Triple Negative Breast Cancer by Promoting MDM2-mediated Apelin Degradation
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    authorea.com/users/962058/articles/1331009-hispidulin-inhibits-metastasis-of-triple-negative-breast-cancer-by-promoting-mdm2-mediated-apelin-degradation
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    USP18 Inhibition Enhances Type I Interferon Signalling and Immune Activation in the Tumour Microenvironment of Triple-Negative Breast Cancer
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    biorxiv.org/content/10.1101/2025.09.01.672152v1
  17. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Targeted Reprogramming of Tumor Cells by Digoxin-Loaded Immunogenic Nanoparticles Enhances Immunity Against Disseminated Tumor Cells
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    advanced.onlinelibrary.wiley.com/doi/10.1002/adhm.202502881
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Novel Chimeric CTLA-4 B-cell Epitope Peptide Vaccines Demonstrate Effective Antitumor Immunity with/without PD1/PDL1 Blockade in Multiple Syngeneic Murine Models of Breast and Colorectal Cancers
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    pmc.ncbi.nlm.nih.gov/articles/PMC12402803/
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    Enzyme-mediated nanoreactors with cascade metabolic modulation for enhanced chemo-chemodynamic combination therapy
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    sciencedirect.com/science/article/pii/S0021979725023379
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    Hyperbaric oxygen augments Doxil antitumor efficacy by reducing tumor-induced lactate
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    sciencedirect.com/science/article/pii/S016836592500793X
  21. Aug 2025
  22. www.sciencedirect.com www.sciencedirect.com
    Biomimetic nanoimmunotherapy boosts spatiotemporal PANoptosis and reshapes desmoplastic tumor microenvironment
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    sciencedirect.com/science/article/pii/S2666379125003854
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    A customized immunomodulator reinforces the T cell-mediated immunological cascade for cancer therapy
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    sciencedirect.com/science/article/pii/S1385894725080702
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    Inhibition of tumor cell macropinocytosis driver DHODH reverses immunosuppression and overcomes anti-PD1 resistance
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    sciencedirect.com/science/article/pii/S107476132500322X
  25. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Novel Swelling-Lytic Cell Death Triggered by Cargo-Free Ionizable Lipid Nanoparticles
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202509208
  26. www.sciencedirect.com www.sciencedirect.com
    A Metallic Metabolic Nano-Regulator Reprograms the PKM2/HIF-1α/DLAT Axis to Amplify Tumor-Specific Cuproptosis
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    sciencedirect.com/science/article/pii/S0142961225005459
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    Bifunctional KatG-Mimic Activity of Nanosheet for Coupled Catalytic Therapy of Hypoxic Tumor
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    advanced.onlinelibrary.wiley.com/doi/10.1002/adhm.202502490
  28. www.nature.com www.nature.com
    NSD2 inhibitors rewire chromatin to treat lung and pancreatic cancers
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    nature.com/articles/s41586-025-09299-y
  29. www.sciencedirect.com www.sciencedirect.com
    Analysis of nanomedicine primary tumor vs. metastasis targeting using clinical-stage core-crosslinked polymeric micelles
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    sciencedirect.com/science/article/pii/S2211124725008575
  30. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    PD-L1-Targeting Biomimetic Photoresponsive Thermosensitive Liposomes for Triple-Negative Breast Cancer
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202506841
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Four Amino Acid Intracellular Motif of VISTA Blocks Growth Receptor Signaling in Cancer Cells to Induce Tumor Suppression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12317733/
  32. www.biorxiv.org www.biorxiv.org
    PEGylation strategies for enhanced nanoparticle delivery to tumor associated immune cells
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    biorxiv.org/content/10.1101/2025.07.23.666401v1
  33. Jul 2025
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MARCO expression on myeloid-derived suppressor cells is essential for their differentiation and immunosuppression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12283920/
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Diabetes is causally associated with increased breast cancer mortality by inducing FIBCD1 to activate MCM5-mediated cell cycle arrest via modulating H3K27ac
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    pmc.ncbi.nlm.nih.gov/articles/PMC12283923/
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MSN/STAT3 drives cancer stemness and chemoresistance via IL-6/LPAR1 ligand receptor complex in triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12281688/
  37. www.mdpi.com www.mdpi.com
    Targeting Triple-Negative Breast Cancer with Momordicine-I for Therapeutic Gain in Preclinical Models
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    mdpi.com/2072-6694/17/14/2342
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    Glucose restriction shapes pre-metastatic innate immune landscapes in the lung through exosomal TRAIL
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    sciencedirect.com/science/article/pii/S0092867425007287
  39. dx.doi.org dx.doi.org
    Genetic and pharmacological targeting of nicotinic acetylcholine receptor action blocks tumor progression in mouse models of breast cancer
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    dx.doi.org/10.1093/jimmun/vkaf148
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    Subtherapeutic Dose of Ionizing Radiation Reprograms the Pre-Metastatic Lung Niche, Accelerating Its Formation and Promoting Metastasis
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    mdpi.com/1422-0067/26/13/6145
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    A Rac-specific competitive inhibitor of guanine nucleotide binding reduces metastasis in triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2666379125003064
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    Covalent inhibition of ACSL4 alleviates ferroptosis-induced acute liver injury
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    sciencedirect.com/science/article/pii/S2451945625001990
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ammonia Suppresses the Antitumor Activity of Natural Killer Cells and T Cells by Decreasing Mature Perforin
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    pmc.ncbi.nlm.nih.gov/articles/PMC12214879/
  44. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    DNA Barcoding-Enabled Tracking of Lipid Nanoparticles: Drug-Loading-Dependent Biodistribution and Tumor Microenvironment Targeting
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    advanced.onlinelibrary.wiley.com/doi/10.1002/adhm.202501914
  45. Jun 2025
  46. www.nature.com www.nature.com
    Nerve-to-cancer transfer of mitochondria during cancer metastasis
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    nature.com/articles/s41586-025-09176-8
  47. www.sciencedirect.com www.sciencedirect.com
    VISTA immune checkpoint blunts radiotherapy-induced antitumor immune response
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    sciencedirect.com/science/article/pii/S2211124725006643
  48. link.springer.com link.springer.com
    Sonoafterglow nanoprobes for deep-tissue imaging of peroxynitrite
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    link.springer.com/article/10.1038/s41596-025-01202-3
  49. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An Acrolein-Based Drug Delivery System Enables Tumor-Specific Sphingosine-1-Phosphate Targeting in Breast Cancer without Lymphocytopenia
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    pmc.ncbi.nlm.nih.gov/articles/PMC12174973/
  50. www.tandfonline.com www.tandfonline.com
    Enhanced Sonodynamic Therapy via Au Nanoclusters Deposited on TiO2 Nanosheets
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    tandfonline.com/doi/abs/10.2147/IJN.S516314
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    Preparation and biomedical applications of single-metal atom catalysts
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    link.springer.com/article/10.1038/s41596-025-01199-9
  52. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Immune targeting of triple-negative breast cancer through a clinically actionable STING agonist-CAR T cell platform
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    pmc.ncbi.nlm.nih.gov/articles/PMC12281382/
  53. www.sciencedirect.com www.sciencedirect.com
    Arachidonic acid triggers spermidine synthase secretion from primary tumor to induce skeletal muscle weakness upon irradiation
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    sciencedirect.com/science/article/pii/S1550413125002694
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  55. May 2025
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Combination of MIF Inhibitor and AEP Targeted Inhibitor to Reduce Lung Metastasis in Breast Cancer and Its Mechanism
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    pmc.ncbi.nlm.nih.gov/articles/PMC12102665/
  57. link.springer.com link.springer.com
    NECTIN4 regulates the cell surface expression of CD155 in non-small cell lung cancer cells and induces tumor resistance to PD-1 inhibitors
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    link.springer.com/article/10.1007/s00262-025-04079-z
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    High-resolution quantitative mapping of extracellular pH by ratiometric MRI with iron chelates in a tumor mouse model
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    link.springer.com/article/10.1007/s11547-025-02020-z
  59. www.sciencedirect.com www.sciencedirect.com
    Serotonin transporter inhibits antitumor immunity through regulating the intratumoral serotonin axis
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    sciencedirect.com/science/article/pii/S0092867425005021
  60. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Enhanced Sonodynamic Therapy via Au Nanoclusters Deposited on TiO2 Nanosheets
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    pmc.ncbi.nlm.nih.gov/articles/PMC12085897/
  61. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Antitumor CD4+ T Helper 1 Cells Target and Control the Outgrowth of Disseminated Cancer Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12046335/
  62. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Reducing Dietary Protein Enhances the Antitumor Effects of Chemotherapy through Immune-Mediated Mechanisms
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    pmc.ncbi.nlm.nih.gov/articles/PMC7617599/
  63. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A novel synthesised STAT3 inhibitor exerts potent anti-tumour activity by inducing lysosome-dependent cell death
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70071
  64. www.sciencedirect.com www.sciencedirect.com
    Sumoylated Etv1 establishes mouse mammary cancer stem cells that support tumorigenesis by non-stem cancer cells
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    sciencedirect.com/science/article/pii/S1534580725002072
  65. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Inhibition of autotaxin activity with IOA-289 decreases fibrosis in mouse E0771 breast tumors
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    onlinelibrary.wiley.com/doi/10.1002/ijc.35471
  66. Apr 2025
  67. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RHBDF1 promotes PERK expression through the JNK/FoxO3 pathway in breast cancer cells: RHBDF1 promotes PERK expression through the JNK/FoxO3 axis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11986452/
  68. www.sciencedirect.com www.sciencedirect.com
    N-(5-(2-morpholino-4-oxo-3,4-dihydroquinazolin-8-yl)pyridin-2-yl)acylamides as novel multi-PI3K/DNA-PK/P-gp inhibitors for efficient chemosensitization and MDR alleviation
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    sciencedirect.com/science/article/pii/S0223523425004064
  69. www.biorxiv.org www.biorxiv.org
    Inhibition of EMT driver PTK6 enhances anti-tumor immune responses against triple-negative breast cancer
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    biorxiv.org/content/10.1101/2025.01.11.632044v1
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    Bro1 proteins determine tumor immune evasion and metastasis by controlling secretion or degradation of multivesicular bodies
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    sciencedirect.com/science/article/pii/S1534580725001558
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    Cancer cell-derived arginine fuels polyamine biosynthesis in tumor-associated macrophages to promote immune evasion
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  73. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Trabectedin Enhances the Antitumor Effects of IL-12 in Triple-Negative Breast Cancer
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  74. 52.53.155.43 52.53.155.43
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  76. Mar 2025
  77. www.sciencedirect.com www.sciencedirect.com
    KIF2C promotes paclitaxel resistance by depolymerizing polyglutamylated microtubules
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    Glutamine binds HSC70 to transduce signals inhibiting IFN-β-mediated immunogenic cell death
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    PAI-1-driven SFRP2high cancer-associated fibroblasts hijack the abscopal effect of radioimmunotherapy
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  81. www.cell.com www.cell.com
    Metabolic engineering to facilitate anti-tumor immunity
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    cell.com/cancer-cell/abstract/S1535-6108(25)00056-X
  82. www.biorxiv.org www.biorxiv.org
    TEAD inhibition alters the lung immune microenvironment and attenuates metastasis
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    biorxiv.org/content/10.1101/2025.02.26.639326v1
  83. Feb 2025
  84. analyticalsciencejournals.onlinelibrary.wiley.com analyticalsciencejournals.onlinelibrary.wiley.com
    Multifunctional Docetaxel Cholesterol-Polyethylene Glycol Co-Modified Poly (N-Butyl) Cyanoacrylate Nanoparticles for Brain Tumor Therapy
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    analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/ddr.70069
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    Bidirectional activation of stem-like programs between metastatic cancer and alveolar type 2 cells within the niche
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  86. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Manipulating the cGAS-STING Axis: advancing innovative strategies for osteosarcoma therapeutics
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    pmc.ncbi.nlm.nih.gov/articles/PMC11842356/
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    An epitope-directed mRNA vaccine inhibits tumor metastasis through the blockade of MICA/B α1/2 shedding
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    Potentiating anti-tumor immunity by re-engaging immune synapse molecules
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13817
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    Extracellular vesicles from the lung pro-thrombotic niche drive cancer-associated thrombosis and metastasis via integrin beta 2
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  91. aacrjournals.org aacrjournals.org
    Triple-negative breast cancer-derived extracellular vesicles promote a hepatic pre-metastatic niche via a cascade of microenvironment remodeling
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    aacrjournals.org/mcr/article/21/7/726/727474/Triple-Negative-Breast-Cancer-Derived
  92. aacrjournals.org aacrjournals.org
    Arginine methylation of DDX3 by PRMT1 mediates mitochondrial homeostasis to promote breast cancer metastasis
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