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433 Matching Annotations

Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Invention of circRNA promoting RNA to specifically promote circRNA production

1
1. scibot 26 Sep 2024
  
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  RRID:CVCL_0336
  
  DOI: 10.1093/nar/gkae693
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11417354/
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Sorafenib and SIAIS361034, a novel PROTAC degrader of BCL-xL, display synergistic antitumor effects on hepatocellular carcinoma with minimal hepatotoxicity

1
1. scibot 17 Sep 2024
  
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  RRID:CVCL_0336
  
  DOI: 10.1016/j.bcp.2024.116542
  
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sciencedirect.com/science/article/pii/S0006295224005422
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Harnessing Porphyrin Accumulation in Liver Cancer: Combining Genomic Data and Drug Targeting

1
1. scibot 30 Aug 2024
  
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  RRID:CVCL_0336
  
  DOI: 10.3390/biom14080959
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11352895/
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YTHDF3-mediated m6A modification of NKD1 regulates hepatocellular carcinoma invasion and metastasis by activating the WNT/β-catenin signaling axis

1
1. scibot 20 Aug 2024
  
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  DOI: 10.1016/j.yexcr.2024.114192
  
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sciencedirect.com/science/article/pii/S0014482724002830
academic.oup.com academic.oup.com

GNA14’s interaction with RACK1 inhibits Hepatocellular Carcinoma progression through reducing MAPK/JNK and PI3K/AKT signaling pathway

1
1. scibot 02 Aug 2024
  
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  RRID: CVCL_0336
  
  DOI: 10.1093/carcin/bgab098
  
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academic.oup.com/carcin/article/42/11/1357/6398702
Jul 2024
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ASGR1 Is a Promising Target for Lipid Reduction in Pigs with PON2 As Its Inhibitor

1
1. scibot 18 Jul 2024
  
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  DOI: 10.1016/j.isci.2024.110288
  
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sciencedirect.com/science/article/pii/S258900422401513X
link.springer.com link.springer.com

TGF-β1-Induced LINC01094 promotes epithelial-mesenchymal transition in hepatocellular carcinoma through the miR-122-5p/TGFBR2–SAMD2–SMAD3 Axis

1
1. scibot 18 Jul 2024
  
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  RRID:CVCL_0336
  
  DOI: 10.1007/s10142-024-01403-1
  
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link.springer.com/article/10.1007/s10142-024-01403-1
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The TSC22D, WNK, and NRBP gene families exhibit functional buffering and evolved with Metazoa for cell volume regulation

1
1. scibot 17 Jul 2024
  
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  RRID: CVCL_0336
  
  DOI: 10.1016/j.celrep.2024.114417
  
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sciencedirect.com/science/article/pii/S2211124724007460
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Novel proteolytic activation of Ebolavirus glycoprotein GP by TMPRSS2 and cathepsin L at an uncharted position can compensate for furin cleavage

1
1. scibot 17 Jul 2024
  
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  CVCL_0336
  
  DOI: 10.1016/j.virusres.2024.199430
  
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sciencedirect.com/science/article/pii/S0168170224001230
www.cell.com www.cell.com

Cyclin dependent kinase 9 inhibition reduced programmed death-ligand 1 expression and improved treatment efficacy in hepatocellular carcinoma

1
1. scibot 12 Jul 2024
  
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  RRID:CVCL_0336
  
  DOI: 10.1016/j.heliyon.2024.e34289
  
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cell.com/heliyon/fulltext/S2405-8440(24)10320-9
Jun 2024
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Development of a PCSK9-targeted nanoparticle vaccine to effectively decrease the hypercholesterolemia

1
1. scibot 21 Jun 2024
  
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  RRID:CVCL_0336
  
  DOI: 10.1016/j.xcrm.2024.101614
  
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sciencedirect.com/science/article/pii/S2666379124003185
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Hypoxia-responsive lncRNA MIR155HG promotes PD-L1 expression in hepatocellular carcinoma cells by enhancing HIF-1α mRNA stability

1
1. scibot 21 Jun 2024
  
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  RRID:CVCL_0336
  
  DOI: 10.1016/j.intimp.2024.112415
  
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sciencedirect.com/science/article/pii/S1567576924009366
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Protein and metabolic profiles of tyrosine kinase inhibitors co-resistant liver cancer cells

1
1. scibot 09 Jun 2024
  
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  RRID:CVCL_0336
  
  DOI: 10.3389/fphar.2024.1394241
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11149701/
52.53.155.43 52.53.155.43

Cancer-associated fibroblasts derived fibronectin extra domain A promotes sorafenib resistance in hepatocellular carcinoma cells by activating SHMT1

1
1. scibot 07 Jun 2024
  
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  RRID:CVCL_0336
  
  DOI: 10.1016/j.gendis.2024.101330
  
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52.53.155.43/4ce03cbacce8413db4e1f65c5bc64f875e4f505b/1-s2.0-S2352304224001272-main-html.html
link.springer.com link.springer.com

STEAP2 promotes hepatocellular carcinoma progression via increased copper levels and stress-activated MAP kinase activity

1
1. scibot 06 Jun 2024
  
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  RRID:CVCL_0336
  
  DOI: 10.1038/s41598-024-63368-2
  
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link.springer.com/article/10.1038/s41598-024-63368-2
May 2024
www.cell.com www.cell.com

An unconventional VH1-2 antibody tolerates escape mutations and shows an antigenic hotspot on SARS-CoV-2 spike

1
1. scibot 30 May 2024
  
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  RRID: CVCL_0336
  
  DOI: 10.1016/j.celrep.2024.114265
  
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  Curator: @abever99
  
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  RRID:CVCL_0336 DOI:10.1016/j.celrep.2024.114265
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DOI:10.1016/j.celrep.2024.114265

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cell.com/cell-reports/fulltext/S2211-1247(24)00593-X
www.nature.com www.nature.com

cGAS suppresses hepatocellular carcinoma independent of its cGAMP synthase activity

1
1. scibot 26 May 2024
  
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  CVCL-0336
  
  DOI: 10.1038/s41418-024-01291-9
  
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  Curator: @bandrow
  
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  RRID:CVCL_0336 DOI:10.1038/s41418-024-01291-9
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DOI:10.1038/s41418-024-01291-9

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nature.com/articles/s41418-024-01291-9
aacrjournals.org aacrjournals.org

β-catenin Activation Reprograms Ammonia Metabolism to Promote Senescence Resistance in Hepatocellular Carcinoma

1
1. scibot 23 May 2024
  
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  RRID: CVCL_0336
  
  DOI: 10.1158/0008-5472.CAN-23-0673
  
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  RRID:CVCL_0336 DOI:10.1158/0008-5472.CAN-23-0673
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DOI:10.1158/0008-5472.CAN-23-0673

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aacrjournals.org/cancerres/article/84/10/1643/745304/Catenin-Activation-Reprograms-Ammonia-Metabolism
aacrjournals.org aacrjournals.org

DNA of neutrophil extracellular traps binds TMCO6 to impair CD8+ T-cell immunity in hepatocellular carcinoma.

1
1. scibot 23 May 2024
  
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  RRID: CVCL_0336
  
  DOI: 10.1158/0008-5472.CAN-23-2986
  
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  RRID:CVCL_0336 DOI:10.1158/0008-5472.CAN-23-2986
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aacrjournals.org/cancerres/article/84/10/1613/745317/DNA-of-Neutrophil-Extracellular-Traps-Binds-TMCO6
onlinelibrary.wiley.com onlinelibrary.wiley.com

Lenvatinib-resistant hepatocellular carcinoma promotes malignant potential of tumor-associated macrophages via exosomal miR-301a-3p

1
1. scibot 16 May 2024
  
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  RRID:CVCL_0336
  
  DOI: 10.1002/ags3.12814
  
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onlinelibrary.wiley.com/doi/10.1002/ags3.12814
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Bioengineering scalable and drug-responsive in vitro human multicellular non-alcoholic fatty liver disease microtissues encapsulated in the liver extracellular matrix-derived hydrogel

1
1. scibot 15 May 2024
  
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  RRID:CVCL_0336
  
  DOI: 10.17179/excli2023-6878
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11089098/
52.53.155.43 52.53.155.43

Pathway metabolite ratios reveal distinctive glutamine metabolism in a subset of proliferating cells

2
1. scibot 10 May 2024
  
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  RRID:CVCL_0336
  
  DOI: 10.1101/2024.02.18.580900
  
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2. scibot 10 May 2024
  
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  RRID:CVCL_0336
  
  DOI: 10.1101/2024.02.18.580900
  
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52.53.155.43/97841ca504d9556b3965877911b65905cd7f6735/2024.02.18.580900v1.full-html.html
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

FEBS Press

1
1. scibot 02 May 2024
  
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  RRID:CVCL_0336
  
  DOI: 10.1002/1873-3468.14889
  
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febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.14889
Apr 2024
dx.doi.org dx.doi.org

Endophytic Streptomyces sp. MSARE05 isolated from roots of Peanut plant produces a novel antimicrobial compound

1
1. scibot 26 Apr 2024
  
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  RRID:CVCL_0336
  
  DOI: 10.1093/jambio/lxae051
  
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dx.doi.org/10.1093/jambio/lxae051
www.sciencedirect.com www.sciencedirect.com

Turnover of PPP1R15A mRNA encoding GADD34 controls responsiveness and adaptation to cellular stress

1
1. scibot 12 Apr 2024
  
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  RRID:CVCL_0336
  
  DOI: 10.1016/j.celrep.2024.114069
  
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sciencedirect.com/science/article/pii/S2211124724003978
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Chemically engineered mTOR-nanoparticle blockers enhance antitumour efficacy

1
1. scibot 11 Apr 2024
  
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  RRID:CVCL_0336
  
  DOI: 10.1016/j.ebiom.2024.105099
  
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sciencedirect.com/science/article/pii/S2352396424001348
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

ISG12a promotes immunotherapy of HBV-associated hepatocellular carcinoma through blocking TRIM21/AKT/β-Catenin/PD-L1 axis

1
1. scibot 10 Apr 2024
  
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  RRID:CVCL_0336
  
  DOI: 10.1016/j.isci.2024.109533
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11000115/
Mar 2024
www.sciencedirect.com www.sciencedirect.com

Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling

1
1. scibot 29 Mar 2024
  
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  Cat#JCRB0403
  
  DOI: 10.1016/j.chembiol.2024.02.013
  
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sciencedirect.com/science/article/pii/S2451945624000874
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A prognostic and immune related risk model based on zinc homeostasis in hepatocellular carcinoma

1
1. scibot 22 Mar 2024
  
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  RRID:CVCL_0336
  
  DOI: 10.1016/j.isci.2024.109389
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10951649/
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Convergent evolution and targeting of diverse E2 epitopes by human broadly neutralizing antibodies are associated with HCV clearance

1
1. scibot 22 Mar 2024
  
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  RRID:CVCL_0336
  
  DOI: 10.1016/j.immuni.2024.03.001
  
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sciencedirect.com/science/article/pii/S1074761324000979
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

SUMOylation controls Hu antigen R posttranscriptional activity in liver cancer

1
1. scibot 21 Mar 2024
  
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  JCRB0403
  
  DOI: 10.1016/j.celrep.2024.113924
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11025316/
www.biorxiv.org www.biorxiv.org

Stabilization of AMPK/PFKL/RPIA in the Glycolytic Bodies Transduces IL6/STAT3 Signal in Hepatocarcinogenesis

1
1. scibot 21 Mar 2024
  
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  RRID:CVCL_0336
  
  DOI: 10.1101/2024.02.29.582877
  
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biorxiv.org/content/10.1101/2024.02.29.582877v1
Feb 2024
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Inhibition of RhoGEF/RhoA alleviates regorafenib resistance and cancer stemness via Hippo signaling pathway in hepatocellular carcinoma

1
1. scibot 09 Feb 2024
  
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  RRID:CVCL_0336
  
  DOI: 10.1016/j.yexcr.2024.113956
  
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sciencedirect.com/science/article/pii/S0014482724000466
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CREB3L4 promotes hepatocellular carcinoma progression and decreases sorafenib chemosensitivity by promoting RHEB-mTORC1 signaling pathway

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ASPM stabilizes the NOTCH intracellular domain 1 and promotes oncogenesis by blocking FBXW7 binding in hepatocellular carcinoma cells

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A conserved Y-shaped RNA structure in the 3’UTR of chikungunya virus genome as a host-specialized element that modulates viral replication and evolution

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A high throughput antiviral screening platform for alphaviruses based on Semliki Forest virus expressing eGFP reporter gene

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Results of German external quality assessment schemes for SARS-CoV-2 antigen detection

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Insights from the Construction of Adenovirus-Based Vaccine Candidates against SARS-CoV-2: Expecting the Unexpected

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SUMOylated IL-33 in the nucleus stabilizes the transcription factor IRF1 in hepatocellular carcinoma cells to promote immune escape

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PZR suppresses innate immune response to RNA viral infection by inhibiting MAVS activation in interferon signaling mediated by RIG-I and MDA5

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SARS-CoV-2 BA.2.86 enters lung cells and evades neutralizing antibodies with high efficiency

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Histone methyltransferase SUV420H1/KMT5B contributes to poor prognosis in hepatocellular carcinoma

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SUMOylation inhibitors activate anti-tumor immunity by reshaping the immune microenvironment in a preclinical model of hepatocellular carcinoma

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Dengue and Zika RNA-RNA interactomes reveal pro- and anti-viral RNA in human cells

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A Cell Surface-Binding Antibody Atlas Nominates a MUC18-Directed Antibody–Drug Conjugate for Targeting Melanoma

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NIR-II fluorescence-guided liver cancer surgery by a small molecular HDAC6 targeting probe

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3D printing injectable microbeads using a composite liposomal ink for local treatment of peritoneal diseases

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Sex difference in liver diseases: How preclinical models help to dissect the sex-related mechanisms sustaining NAFLD and hepatocellular carcinoma

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Anti-tumor effect of PD-L1-targeting antagonistic aptamer-ASO delivery system with dual inhibitory function in immunotherapy

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Decreased B4GALT1 promotes hepatocellular carcinoma cell invasiveness by regulating the laminin-integrin pathway

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Manganese regulation of COPII condensation controls circulating lipid homeostasis

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Immunogenicity of COVID-19 vaccines and their effect on HIV reservoir in older people with HIV

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Synergism of the receptor tyrosine kinase Axl with ErbB receptors mediates resistance to regorafenib in hepatocellular carcinoma

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Molecular Oncology - 2023 - Azbazdar-html.html

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FEBS Press

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SARS-CoV-2 variants with NSP12 P323L/G671S mutations display enhanced virus replication in ferret upper airways and higher transmissibility

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Hypoxia-responsive lncRNA AC115619 encodes a micropeptide that suppresses m6A modifications and hepatocellular carcinoma progression

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Improved approaches to channel capacity estimation discover compromised GPCR signaling in diverse cancer cells

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The Role of miR-1183: A Potential Suppressor in Hepatocellular Carcinoma via Regulating Splicing Factor SRSF1

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MEF2A suppresses stress responses that trigger DDX41-dependent IFN production

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Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice

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An HBV susceptibility variant of KNG1 modulates the therapeutic effects of interferons α and λ1 in HBV infection by promoting MAVS lysosomal degradation

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PPM1H is down-regulated by ATF6 and dephosphorylates p-RPS6KB1 to inhibit progression of hepatocellular carcinoma

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TMEM106B is a receptor mediating ACE2-independent SARS-CoV-2 cell entry

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Upregulation of FAM50A promotes cancer development

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SSRN-id4409313-html.html

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PSMD4 drives progression of hepatocellular carcinoma via Akt/COX2 pathway and p53 inhibition

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Omicron subvariant BA.5 efficiently infects lung cells

1
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  DOI: 10.1038/s41467-023-39147-4
  
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HBx-induced HSPA8 stimulates HBV replication and suppresses ferroptosis to support liver cancer progression

1
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  DOI: 10.1158/0008-5472.CAN-22-3169
  
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Activating an Adaptive Immune Response with a Telomerase-mediated Telomere Targeting Therapeutic in Hepatocellular Carcinoma

1
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  DOI: 10.1158/1535-7163.MCT-23-0039
  
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mct-23-0039-html.html

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May 2023
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Extracellular vesicles in fatty liver promote a metastatic tumor microenvironment

1
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A nanotherapeutic strategy that engages cytotoxic and immunosuppressive activities for the treatment of cancer recurrence following organ transplantation

1
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Cell culture systems for isolation of SARS-CoV-2 clinical isolates and generation of recombinant virus

1
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IL-33/ST2 antagonizes STING signal transduction via autophagy in response to acetaminophen-mediated toxicological immunity

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  DOI: 10.1186/s12964-023-01114-3
  
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AT-752 targets multiple sites and activities on the Dengue virus replication enzyme NS5

1
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  DOI: 10.1016/j.antiviral.2023.105574
  
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FEBS Press

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  DOI: 10.1002/1878-0261.13417
  
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Macrophage CD5L is a target for cancer immunotherapy

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Upregulation of TUBG1 expression promotes hepatocellular carcinoma development

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Feb 2023
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Stiff matrix induces exosome secretion to promote tumour growth

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  DOI: 10.1038/s41556-023-01092-1
  
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A bat MERS-like coronavirus circulates in pangolins and utilizes human DPP4 and host proteases for cell entry

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  DOI: 10.1016/j.cell.2023.01.019
  
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XPO1 intensifies sorafenib resistance by stabilizing acetylation of NPM1 and enhancing epithelial-mesenchymal transition in hepatocellular carcinoma

1
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Jan 2023
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METTL1-mediated m7G tRNA modification promotes lenvatinib resistance in hepatocellular carcinoma

1
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Augmenter of Liver Regeneration Monoclonal Antibody Promotes Apoptosis of Hepatocellular Carcinoma Cells

1
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  DOI: 10.14218/JCTH.2022.00346
  
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ATE1 Inhibits Liver Cancer Progression through RGS5-Mediated Suppression of Wnt/β-Catenin Signaling

1
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  DOI: 10.1158/1541-7786.MCR-21-0027
  
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RNA Helicase DHX37 Facilitates Liver Cancer Progression by Cooperating with PLRG1 to Drive Superenhancer-Mediated Transcription of Cyclin D1

1
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Antisense RNAs Influence Promoter Usage of Their Counterpart Sense Genes in Cancer

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Dec 2022
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WWOX-rs13338697 genotype predicts therapeutic efficacy of ADI-PEG 20 for patients with advanced hepatocellular carcinoma

1
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Long-term variations and potency of neutralizing antibodies against Omicron subvariants after CoronaVac inactivated booster: a 7-month follow-up study

1
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  DOI: 10.1002/jmv.28279
  
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MOSPD2 is an endoplasmic reticulum–lipid droplet tether functioning in LD homeostasis

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DNA Binding and Anticancer Properties of New Pd(II)-Phosphorus Schiff Base Metal Complexes

1
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Implications of differential transcription start site selection on chronic myeloid leukemia and prostate cancer cell protein expression

1
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Host Cell Entry and Neutralization Sensitivity of SARS-CoV-2 Lineages B.1.620 and R.1

1
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  DOI: 10.3390/v14112475
  
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The SARS-CoV-2 Delta-Omicron Recombinant Lineage (XD) Exhibits Immune-Escape Properties Similar to the Omicron (BA.1) Variant

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Nov 2022
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circPRKAA1 activates a Ku80/Ku70/SREBP-1 axis driving de novo fatty acid synthesis in cancer cells

1
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Retrospective immunogenicity analysis of seasonal flu H3N2 vaccines recommended in the past ten years using immunized animal sera

1
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  DOI: 10.1016/j.ebiom.2022.104350
  
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Cobalt-conjugated carbon quantum dots for in vivo monitoring of the pyruvate dehydrogenase kinase inhibitor drug dichloroacetic acid

1
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  DOI: 10.1038/s41598-022-22039-w
  
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GALNT14-mediated O-glycosylation on PHB2 serine-161 enhances cell growth, migration and drug resistance by activating IGF1R cascade in hepatoma cells

1
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  DOI: 10.1038/s41419-022-05419-y
  
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Oct 2022
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Sorbitol dehydrogenase induction of cancer cell necroptosis and macrophage polarization in the HCC microenvironment suppresses tumor progression

1
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Sep 2022
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De novo sphingolipid biosynthesis necessitates detoxification in cancer cells

1
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  DOI: 10.1016/j.celrep.2022.111415
  
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A mosaic-type trimeric RBD-based COVID-19 vaccine candidate induces potent neutralization against Omicron and other SARS-CoV-2 variants

1
1. scibot 22 Sep 2022
  
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  DOI: 10.7554/eLife.78633
  
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Aug 2022
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Identification of potent inhibitors of SARS-CoV-2 infection by combined pharmacological evaluation and cellular network prioritization

1
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Drug transporters are implicated in the diffusion of tacrolimus into the T lymphocyte in kidney and liver transplant recipients: Genetic, mRNA, protein expression, and functionality

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Glutamine deprivation impairs function of infiltrating CD8+ T cells in hepatocellular carcinoma by inducing mitochondrial damage and apoptosis

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https://medrxiv.org/cgi/content/10.1101/2020.10.25.20218990

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GCN2 inhibition sensitizes arginine-deprived hepatocellular carcinoma cells to senolytic treatment

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Integrin alpha 6 (ITGA6) is upregulated and drives hepatocellular carcinoma progression through integrin α6β4 complex

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Establishment of well-differentiated camelid airway cultures to study Middle East respiratory syndrome coronavirus

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An antibacterial compound pyrimidomycin produced by Streptomyces sp. PSAA01 isolated from soil of Eastern Himalayan foothill

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CRISPR/Cas9 Screens Reveal that Hexokinase 2 Enhances Cancer Stemness and Tumorigenicity by Activating the ACSL4-Fatty Acid β-Oxidation Pathway

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SARS-CoV-2 Omicron sublineages show comparable cell entry but differential neutralization by therapeutic antibodies

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Chimeric HDAC and the cytoskeleton inhibitor broxbam as a novel therapeutic strategy for liver cancer

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Blocked metabotropic glutamate receptor 5 enhances chemosensitivity in hepatocellular carcinoma and attenuates chemotoxicity in the normal liver by regulating DNA damage

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SARS-CoV-2 variants C.1.2 and B.1.621 (Mu) partially evade neutralization by antibodies elicited upon infection or vaccination

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Discovery of 5,7-Dimethoxy-2-(3,4,5-trimethoxyphenoxy)-chromen-4-one with Lipid Lowering Effects in Hepatocytes

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In vitro and in vivo assay of the ER lipid scramblase TMEM41B

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Cholesterol suppresses GOLM1-dependent selective autophagy of RTKs in hepatocellular carcinoma

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The interferon-stimulated gene RIPK1 regulates cancer cell intrinsic and extrinsic resistance to immune checkpoint blockade

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The calcium channel inhibitor lacidipine inhibits Zika virus replication in neural progenitor cells

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Deadenylase-dependent mRNA decay of GDF15 and FGF21 orchestrates food intake and energy expenditure

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A phospholipid mimetic targeting LRH-1 ameliorates colitis

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A survey of optimal strategy for signature-based drug repositioning and an application to liver cancer

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Amelioration of hepatic steatosis by dietary essential amino acid-induced ubiquitination

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Alzheimer's disease protease-containing plasma extracellular vesicles transfer to the hippocampus via the choroid plexus

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Establish an assessment model to characterized metastasis ability Single-cell multiomics reveals heterogeneous cell states linked to metastatic potential in liver cancer cell lines

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Anticancer effects of imidazole nucleus in hepatocellular carcinoma cell lines via the inhibition of AKT and ERK1/2 signaling pathways

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A common variant in 11q23.3 associated with hyperlipidemia is mediated by the binding and regulation of GATA4

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ERα inhibits mesenchymal and amoeboidal movement of liver cancer cell via Gα12

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Hepatic MIR20B promotes nonalcoholic fatty liver disease by suppressing PPARA

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The Omicron variant is highly resistant against antibody-mediated neutralization – implications for control of the COVID-19 pandemic

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A genome-wide CRISPR screen identifies interactors of the autophagy pathway as conserved coronavirus targets

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Elevated FBXO45 promotes liver tumorigenesis through enhancing IGF2BP1 ubiquitination and subsequent PLK1 upregulation

1
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The Role of Arginine Metabolism in Oral Tongue Squamous Cell Carcinoma

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Modeling hepatitis C virus kinetics during liver transplantation reveals the role of the liver in virus clearance

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Enhanced Antitumor Effect in Liver Cancer by Amino Acid Depletion-Induced Oxidative Stress

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α-Ketoglutarate Inhibits Thrombosis and Inflammation by Prolyl Hydroxylase-2 Mediated Inactivation of Phospho-Akt

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RBM15 promotes hepatocellular carcinoma progression by regulating N6-methyladenosine modification of YES1 mRNA in an IGF2BP1-dependent manner

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  DOI: 10.1038/s41420-021-00703-w
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8551180/
Oct 2021
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Type 2 diabetes sex-specific effects associated with E167K coding variant in TM6SF2

1
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  DOI: 10.1016/j.isci.2021.103196
  
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5-Hydroxymethyltubercidin exhibits potent antiviral activity against flaviviruses and coronaviruses, including SARS-CoV-2

1
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  RCB1942
  
  DOI: 10.1016/j.isci.2021.103120
  
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NRF2 Dysregulation in Hepatocellular Carcinoma and Ischemia: A Cohort Study and Laboratory Investigation

1
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  RRID:CVCL_0336
  
  DOI: 10.1148/radiol.2020200201
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7526944/
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Application of pseudotyped virus particles to monitor Ebola virus and SARS-CoV-2 viral entry in human cell lines

1
1. scibot 22 Sep 2021
  
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  DOI: 10.1016/j.xpro.2021.100818
  
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Applicability of Scrape Loading-Dye Transfer Assay for Non-Genotoxic Carcinogen Testing

1
1. scibot 04 Sep 2021
  
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  RRID:CVCL_0336
  
  DOI: 10.3390/ijms22168977
  
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FNDC4 acts as an extracellular factor to promote the invasiveness of hepatocellular carcinoma partly via the PI3K/Akt signalling pathway

1
1. scibot 28 Aug 2021
  
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  DOI: 10.1002/cam4.4225
  
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Loss of tyrosine catabolic enzyme HPD promotes glutamine anaplerosis through mTOR signaling in liver cancer

1
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  DOI: 10.1016/j.celrep.2021.109617
  
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Untitled document

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  RRID:CVCL_0336
  
  DOI: 10.1016/j.cmet.2018.12.016
  
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ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency

1
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  JCRB0403
  
  DOI: 10.1016/j.molcel.2021.07.018
  
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Altered m6A Modification of Specific Cellular Transcripts Affects Flaviviridae Infection

1
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  DOI: 10.1016/j.molcel.2019.11.007
  
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Hepatocytes Delete Regulatory T Cells by Enclysis, a CD4+ T Cell Engulfment Process

1
1. scibot 31 Jul 2021
  
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  Huh-7
  
  DOI: 10.1016/j.celrep.2019.09.068
  
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The Cancer SENESCopedia: A delineation of cancer cell senescence

1
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  DOI: 10.1016/j.celrep.2021.109441
  
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GPR146 Deficiency Protects against Hypercholesterolemia and Atherosclerosis

1
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  DOI: 10.1016/j.cell.2019.10.034
  
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Differential Activation of the Transcription Factor IRF1 Underlies the Distinct Immune Responses Elicited by Type I and III Interferons

1
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Untitled document

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  DOI: 10.1371/journal.ppat.1007733
  
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Near-infrared photothermal/photodynamic therapy with indocyanine green induces apoptosis of hepatocellular carcinoma cells through oxidative stress

1
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  HuH-7
  
  DOI: 10.1038/s41598-017-14401-0
  
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Sporadic PCDH18 somatic mutations in EpCAM-positive hepatocellular carcinoma

1
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  HuH7
  
  DOI: 10.1186/s12935-017-0467-x
  
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Role of the Transforming Growth Factor-β in regulating hepatocellular carcinoma oxidative metabolism

1
1. scibot 27 Jul 2021
  
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  Huh7
  
  DOI: 10.1038/s41598-017-12837-y
  
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SARS-CoV-2 variant B.1.617 is resistant to Bamlanivimab and evades antibodies induced by infection and vaccination

1
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Glycerol-3-phosphate biosynthesis regenerates cytosolic NAD+ to alleviate mitochondrial disease

1
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  DOI: 10.1016/j.cmet.2021.06.013
  
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3-hydroxyanthranic acid increases the sensitivity of hepatocellular carcinoma to sorafenib by decreasing tumor cell stemness

1
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  RRID:CVCL_0336
  
  DOI: 10.1038/s41420-021-00561-6
  
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nature.com/articles/s41420-021-00561-6
Jun 2021
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Transcriptionally inactive hepatitis B virus episome DNA preferentially resides in the vicinity of chromosome 19 in 3D host genome upon infection

1
1. scibot 30 Jun 2021
  
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  RRID:CVCL_0336
  
  DOI: 10.1016/j.celrep.2021.109288
  
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CPSF4 regulates circRNA formation and microRNA mediated gene silencing in hepatocellular carcinoma

1
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  RRID:CVCL_0336
  
  DOI: 10.1038/s41388-021-01867-6
  
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Choline kinase alpha 2 acts as a protein kinase to promote lipolysis of lipid droplets

1
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  JCRB0403
  
  DOI: 10.1016/j.molcel.2021.05.005
  
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May 2021
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The autophagy protein Becn1 improves insulin sensitivity by promoting adiponectin secretion via exocyst binding

1
1. scibot 26 May 2021
  
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  Cat#JCRB0403
  
  DOI: 10.1016/j.celrep.2021.109184
  
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The zinc finger protein Miz1 suppresses liver tumorigenesis by restricting hepatocyte-driven macrophage activation and inflammation

1
1. scibot 26 May 2021
  
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TMEM41B acts as an ER scramblase required for lipoprotein biogenesis and lipid homeostasis

1
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  JCRB0403
  
  DOI: 10.1016/j.cmet.2021.05.006
  
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cell.com/cell-metabolism/fulltext/S1550-4131(21)00223-0
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Histone deacetylase inhibitor resminostat in combination with sorafenib counteracts platelet-mediated pro-tumoral effects in hepatocellular carcinoma

1
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  DOI: 10.1038/s41598-021-88983-1
  
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Centrosomal Localization of RXRα Promotes PLK1 Activation and Mitotic Progression and Constitutes a Tumor Vulnerability

1
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  JCRB 0403
  
  DOI: 10.1016/j.devcel.2020.11.012
  
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Receptor-Mediated ER Export of Lipoproteins Controls Lipid Homeostasis in Mice and Humans

1
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  DOI: 10.1016/j.cmet.2020.10.020
  
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Pharmacoproteomics Identifies Kinase Pathways that Drive the Epithelial-Mesenchymal Transition and Drug Resistance in Hepatocellular Carcinoma

1
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  JCRB0403
  
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The kynurenine derivative 3-HAA sensitizes hepatocellular carcinoma to sorafenib by upregulating phosphatases

1
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  RRID:CVCL_0336
  
  DOI: 10.7150/thno.59841
  
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SARS-CoV-2 mutations acquired in mink reduce antibody-mediated neutralization

1
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  DOI: 10.1016/j.celrep.2021.109017
  
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DNAJC5 promotes hepatocellular carcinoma cells proliferation though regulating SKP2 mediated p27 degradation

1
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  DOI: 10.1016/j.bbamcr.2021.118994
  
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SARS-CoV-2 501Y.V2 variants lack higher infectivity but do have immune escape

1
1. scibot 11 Apr 2021
  
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  RRID: CVCL_0336
  
  DOI: 10.1016/j.cell.2021.02.042
  
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sciencedirect.com/science/article/pii/S0092867421002312
Mar 2021
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Functional inhibition of Oct leads to HNF4α upregulation

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1. scibot 18 Mar 2021
  
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  RRID:CVCL_0336
  
  DOI: 10.3892/etm.2021.9780
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7903485/
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Post-transcriptional regulation of antiviral gene expression by N6-methyladenosine

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1. scibot 03 Mar 2021
  
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  RRID:CVCL_0336
  
  DOI: 10.1016/j.celrep.2021.108798
  
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Intein-mediated cytoplasmic reconstitution of a split toxin enables selective cell ablation in mixed populations and tumor xenografts

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1. scibot 02 Mar 2021
  
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  RRID:CVCL_0336
  
  DOI: 10.1073/pnas.2006603117
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7486740/
Feb 2021
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Evasion of type-I interferon by SARS-CoV-2

1
1. scibot 26 Feb 2021
  
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  RRID:CVCL_0336
  
  DOI: 10.1016/j.celrep.2020.108234
  
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A Universal Design of Betacoronavirus Vaccines against COVID-19, MERS, and SARS

1
1. scibot 25 Feb 2021
  
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  RRID:CVCL_0336
  
  DOI: 10.1016/j.cell.2020.06.035
  
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Targeting EphA2 suppresses hepatocellular carcinoma initiation and progression by dual inhibition of JAK1/STAT3 and AKT signaling

1
1. scibot 24 Feb 2021
  
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  JCRB0403
  
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Jan 2021
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CLINICALLY RELEVANT CELL CULTURE MODELS AND THEIR SIGNIFICANCE IN ISOLATION, PATHOGENESIS, VACCINE DEVELOPMENT, REPURPOSING AND SCREENING OF NEW DRUGS FOR SARS-COV-2: A SYSTEMATIC REVIEW

1
1. scibot 29 Jan 2021
  
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  RRID:CVCL_0336
  
  DOI: 10.1016/j.tice.2021.101497
  
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Genome-wide CRISPR-Cas9 knockout library screening identified PTPMT1 in cardiolipin synthesis is crucial to survival in hypoxia in liver cancer

1
1. scibot 27 Jan 2021
  
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  RRID:CVCL_0336
  
  DOI: 10.1016/j.celrep.2020.108676
  
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Dec 2020
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Long non-coding RNA00844 inhibits MAPK signaling to suppress the progression of hepatocellular carcinoma by targeting AZGP1

1
1. scibot 12 Dec 2020
  
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  RRID:CVCL_0336
  
  DOI: 10.21037/atm-20-3848
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7723597/
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Evidence for liver and peripheral immune cells secreting tumor-suppressive extracellular vesicles in melanoma patients

1
1. scibot 07 Dec 2020
  
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  RRID:CVCL_0336
  
  DOI: 10.1016/j.ebiom.2020.103119
  
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RAB5A is associated with genes involved in exosome secretion: Integration of bioinformatics analysis and experimental validation

1
1. scibot 07 Dec 2020
  
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  RRID:CVCL_0336
  
  DOI: 10.1002/jcb.29871
  
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The Short- and Long-Range RNA-RNA Interactome of SARS-CoV-2

1
1. scibot 07 Dec 2020
  
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  RRID:CVCL_0336
  
  DOI: 10.1016/j.molcel.2020.11.004
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7643667/
Oct 2020
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Oral SARS-CoV-2 Inoculation Establishes Subclinical Respiratory Infection with Virus Shedding in Golden Syrian Hamsters

1
1. scibot 14 Oct 2020
  
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  RRID:CVCL_0336
  
  DOI: 10.1016/j.xcrm.2020.100121
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7508015/
elifesciences.org elifesciences.org

A powerful drug combination strategy targeting glutamine addiction for the treatment of human liver cancer

1
1. scibot 10 Oct 2020
  
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  RRID:CVCL_0336
  
  DOI: 10.7554/eLife.56749
  
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Increased dopamine and its receptor dopamine receptor D1 promote tumor growth in human hepatocellular carcinoma

1
1. scibot 10 Oct 2020
  
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  RRID:CVCL_0336
  
  DOI: 10.1002/cac2.12103
  
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onlinelibrary.wiley.com/doi/full/10.1002/cac2.12103
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Evasion of type-I interferon by SARS-CoV-2

1
1. scibot 01 Oct 2020
  
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  RRID:CVCL_0336
  
  DOI: 10.1016/j.celrep.2020.108234
  
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Sep 2020
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mTOR Signaling and SREBP Activity Increase FADS2 Expression and Can Activate Sapienate Biosynthesis

1
1. scibot 26 Sep 2020
  
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  RRID:CVCL_0336
  
  DOI: 10.1016/j.celrep.2020.107806
  
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sciencedirect.com/science/article/pii/S2211124720307877
52.53.155.43 52.53.155.43

The innate immune effector ISG12a promotes cancer immunity by suppressing the canonical Wnt/β-catenin signaling pathway

1
1. scibot 26 Sep 2020
  
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  RRID:CVCL_0336
  
  DOI: 10.1038/s41423-020-00549-9
  
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52.53.155.43/4a6b7d8df5c880ffc700a3bbbc2e9a94b6a09287/s41423-020-00549-9-html.html
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Plasmodium vivax Liver and Blood Stages Recruit the Druggable Host Membrane Channel Aquaporin-3

1
1. scibot 23 Sep 2020
  
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  RRID:CVCL_0336
  
  DOI: 10.1016/j.chembiol.2020.03.009
  
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learn.dcollege.net learn.dcollege.net

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

1
1. scibot 17 Sep 2020
  
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  RRID:CVCL_0336
  
  DOI: 10.1016/j.cell.2020.02.052
  
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learn.dcollege.net/bbcswebdav/xid-536229684_1
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The critical role of dysregulated Hh-FOXM1-TPX2 signaling in human hepatocellular carcinoma cell proliferation

1
1. scibot 17 Sep 2020
  
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  RRID:CVCL_0336
  
  DOI: 10.1186/s12964-020-00628-4
  
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link.springer.com/article/10.1186/s12964-020-00628-4
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Using recombination-dependent lethal mutations to stabilize reporter flaviviruses for rapid serodiagnosis and drug discovery

1
1. scibot 11 Sep 2020
  
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  RRID:CVCL_0336
  
  DOI: 10.1016/j.ebiom.2020.102838
  
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The Exosome Encapsulated microRNAs as Circulating Diagnostic Marker for Hepatocellular Carcinoma with Low Alpha fetoprotein

1
1. scibot 10 Sep 2020
  
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  RRID:CVCL_0336
  
  DOI: 10.1002/ijc.33111
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.33111
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The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity

1
1. scibot 07 Sep 2020
  
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  RRID:CVCL_0336
  
  DOI: 10.1016/j.cell.2020.07.012
  
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APN-mediated phosphorylation of BCKDK promotes hepatocellular carcinoma metastasis and proliferation via the ERK signaling pathway

1
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  RRID: CVCL_0336
  
  DOI: 10.1038/s41419-020-2610-1
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7249043/
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NOD2 inhibits tumorigenesis and increases chemosensitivity of hepatocellular carcinoma by targeting AMPK pathway

1
1. scibot 03 Sep 2020
  
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  RRID: CVCL-0336
  
  DOI: 10.1038/s41419-020-2368-5
  
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nature.com/articles/s41419-020-2368-5

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