384 Matching Annotations
  1. Jun 2025
  2. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Epigenome‐wide association study, meta‐analysis, and multiscore profiling of whole blood in Parkinson's disease
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    onlinelibrary.wiley.com/doi/10.1002/acn3.52292
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Subregional analysis of the amygdala, thalamus, and hypothalamus at the pre-decline stage in Parkinson’s disease with later cognitive impairment
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    pmc.ncbi.nlm.nih.gov/articles/PMC12098468/
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An individualized tractography pipeline for the nucleus basalis of Meynert lateral tract
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    pmc.ncbi.nlm.nih.gov/articles/PMC12148219/
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Optimizing wrist-worn wearable compliance with insights from two Parkinson’s disease cohort studies
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    pmc.ncbi.nlm.nih.gov/articles/PMC12144100/
  6. www.sciencedirect.com www.sciencedirect.com
    Wearables-derived risk score for unintrusive detection of α-synuclein aggregation or dopaminergic deficit
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    sciencedirect.com/science/article/pii/S2352396425002269
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Longitudinal prevalence of neurogenic orthostatic hypotension in the idiopathic Parkinson Progression Marker Initiative (PPMI) cohort
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    pmc.ncbi.nlm.nih.gov/articles/PMC11128342/
  8. movementdisorders.onlinelibrary.wiley.com movementdisorders.onlinelibrary.wiley.com
    The Parkinson's Disease Cognitive Composite: Lessons Forgotten from Preclinical Alzheimer's Cognitive Composites
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    movementdisorders.onlinelibrary.wiley.com/doi/10.1002/mds.30246
  9. May 2025
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    T cell responses towards PINK1 and α-synuclein are elevated in prodromal Parkinson’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC12106619/
  11. www.sciencedirect.com www.sciencedirect.com
    Motor asymmetry in Parkinson’s disease: Diagnostic thresholds based on clinical scores and DaTSCAN imaging
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    sciencedirect.com/science/article/pii/S2590112525000544
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Examining the Relationship Between Physical Function and Anxiety/Depression in Parkinson's
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    pmc.ncbi.nlm.nih.gov/articles/PMC12105650/
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pre-symptomatic Parkinson’s disease blood test quantifying repetitive sequence motifs in transfer RNA fragments
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    pmc.ncbi.nlm.nih.gov/articles/PMC12092246/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Early BMI Change, Cognitive Decline, and CSF AD Biomarkers Alterations in Parkinson's Disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC12093342/
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Relationships between neuropsychiatric symptoms, subtypes of astrocyte activities, and brain pathologies in Alzheimer's disease and Parkinson's disease
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12089078/
  16. www.neurology.org www.neurology.org
    Predicting CSF α-Synuclein Seed Amplification Assay Status From Demographics and Clinical Data | Neurology Open Access
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    neurology.org/doi/10.1212/WN9.0000000000000008
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Independent validation of the PrecivityAD2™ blood test to identify presence or absence of brain amyloid pathology in individuals with cognitive impairment
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12036378/
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Predicting dementia in people with Parkinson’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC12075756/
  19. www.nature.com www.nature.com
    Modulatory effect of levodopa on the basal ganglia-cerebellum connectivity in Parkinson’s disease
    1
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    nature.com/articles/s41531-025-00954-9
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Item Response Modeling and Artificial Neural Network for Differentiation of Parkinson's Patients and Subjects Without Evidence of Dopaminergic Deficit
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12072227/
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Plasma Glucosylceramide Levels Are Regulated by ATP10D and Are Not Involved in Parkinson's Disease Pathogenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12010051/
  22. Apr 2025
  23. www.neurology.org www.neurology.org
    α-Synuclein Seed Amplification Assay Amplification Parameters and the Risk of Progression in Prodromal Parkinson Disease | Neurology
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    neurology.org/doi/10.1212/WNL.0000000000210279
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Hyposmia in Parkinson’s disease; exploring selective odour loss
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    pmc.ncbi.nlm.nih.gov/articles/PMC11971265/
  25. journals.plos.org journals.plos.org
    An integrative network approach for longitudinal stratification in Parkinson’s disease
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    journals.plos.org/ploscompbiol/article
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Decline in striatal binding ratio associated with accelerated decline in performance on symbol digit modality but not MoCA in Parkinson’s Disease Psychosis
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11962800/
  27. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Domain‐Specific Prediction of Clinical Progression in Parkinson's Disease Using the Mosaic Approach
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    onlinelibrary.wiley.com/doi/10.1002/brb3.70289
  28. www.medrxiv.org www.medrxiv.org
    Amplification parameters of the alpha-synuclein seed amplification assay on CSF predict the clinical subtype of Parkinson’s Disease at 10-year follow-up
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    medrxiv.org/content/10.1101/2025.03.27.25324778v1
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Carriers of LRRK2 pathogenic variants show a milder, anatomically distinct brain signature of Parkinson’s disease
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11952604/
  30. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Dopamine Transporter Imaging as Objective Monitoring Biomarker in Parkinson's Disease
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    onlinelibrary.wiley.com/doi/10.1002/ana.27223
  31. Mar 2025
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    LRRK2-associated parkinsonism with and without in vivo evidence of alpha-synuclein aggregates: longitudinal clinical and biomarker characterization
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    pmc.ncbi.nlm.nih.gov/articles/PMC11925012/
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    History of Traumatic Brain Injury Does Not Influence Rate of Progression of Clinical or Pathological Outcomes in Two Early Parkinson's Disease Cohorts
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    pmc.ncbi.nlm.nih.gov/articles/PMC11926254/
  34. www.medrxiv.org www.medrxiv.org
    Using polygenic and transcriptional risk scores to investigate psychiatric and cognitive symptoms in Parkinson’s disease
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    medrxiv.org/content/10.1101/2025.03.20.25324166v1
  35. www.medrxiv.org www.medrxiv.org
    Longitudinal Assessment of DNA Repair Signature Trajectory in Prodromal versus Established Parkinson’s Disease
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    medrxiv.org/content/10.1101/2025.03.19.25324249v1
  36. www.sciencedirect.com www.sciencedirect.com
    Free Water Imaging Reveals Asynchronous Dopaminergic Degeneration in Substantia Nigra and Ventral Tegmental Area in Prodromal and Early Parkinson's Disease
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    sciencedirect.com/science/article/pii/S0361923025001212
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    AskBeacon—performing genomic data exchange and analytics with natural language
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    pmc.ncbi.nlm.nih.gov/articles/PMC11889448/
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Bidirectional relationship between depression and activities of daily living and longitudinal mediation of cognitive function in patients with Parkinson’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11861111/
  39. www.medrxiv.org www.medrxiv.org
    Nasal septum deviation correlates with asymmetry in Parkinson’s disease
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    medrxiv.org/content/10.1101/2025.02.27.25322941v1
  40. www.medrxiv.org www.medrxiv.org
    A monoclonal antibody-based immunoassay reinforces DOPA decarboxylase in cerebrospinal fluid as a diagnostic and prognostic biomarker for Parkinson’s disease
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    medrxiv.org/content/10.1101/2025.02.26.25322938v1
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Male sex accelerates cognitive decline in GBA1 Parkinson’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11880540/
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Epigenetic insights into neuropsychiatric and cognitive symptoms in Parkinson’s disease: A DNA co-methylation network analysis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11873129/
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RGS10 attenuates systemic immune dysregulation induced by chronic inflammatory stress
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    pmc.ncbi.nlm.nih.gov/articles/PMC11852585/
  44. Feb 2025
  45. www.medrxiv.org www.medrxiv.org
    Progression GWAS followed by functional characterization implicates E3 ubiquitin ligase TRIM2 as a potential genetic modifier of Parkinson’s disease progression
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    medrxiv.org/content/10.1101/2025.02.21.25322301v1
  46. www.medrxiv.org www.medrxiv.org
    Contralateral spread of unilateral tremor in Parkinson’s Disease
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    medrxiv.org/content/10.1101/2025.02.20.25322608v1
  47. www.sciencedirect.com www.sciencedirect.com
    Can we detect cognitive “super-agers” in Parkinson’s disease? Cognitive, neuropsychiatric and motor outcomes in the first 10 years of Parkinson’s disease.
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    sciencedirect.com/science/article/pii/S1353802025000860
  48. www.nature.com www.nature.com
    Patient-centered brain transcriptomic and multimodal imaging determinants of clinical progression, physical activity, and treatment needs in Parkinson’s disease
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    nature.com/articles/s41531-025-00878-4
  49. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Motor and nonmotor features of p.A53T alpha-synuclein PD vs idiopathic PD: longitudinal data from the PPMI study
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    pmc.ncbi.nlm.nih.gov/articles/PMC11814018/
  50. 52.53.155.43 52.53.155.43
    A3.2.full-html.html
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    52.53.155.43/19ead0054ea7b2491e9b9e8b2a2e2240e41d75c6/A3.2.full-html.html
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Transcriptomics profiling of Parkinson’s disease progression subtypes reveals distinctive patterns of gene expression
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    pmc.ncbi.nlm.nih.gov/articles/PMC11791511/
  52. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Increased plasma DOPA decarboxylase levels in Lewy body disorders are driven by dopaminergic treatment
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    pmc.ncbi.nlm.nih.gov/articles/PMC11779843/
  53. www.nature.com www.nature.com
    Relative sparing of dopaminergic terminals in the caudate nucleus is a feature of rest tremor in Parkinson’s disease
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    nature.com/articles/s41531-024-00818-8
  54. www.medrxiv.org www.medrxiv.org
    Decline in striatal binding ratio associated with accelerated decline in performance on Symbol Digit Modality but not MoCA in Parkinson’s disease psychosis
    1
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    medrxiv.org/content/10.1101/2024.08.01.24311353v1
  55. Jan 2025
  56. 52.53.155.43 52.53.155.43
    PDF-html.html
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    52.53.155.43/70ac5fe7573cb1b34a3d891a1139294ea0a7c7d4/PDF-html.html
  57. bpspsychub.onlinelibrary.wiley.com bpspsychub.onlinelibrary.wiley.com
    Dopamine genetic risk scores and psychiatric symptoms: Interacting risk factors for impulse control behaviours in de novo Parkinson's disease
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    bpspsychub.onlinelibrary.wiley.com/doi/10.1111/jnp.12415
  58. www.nature.com www.nature.com
    Sustained effect of prasinezumab on Parkinson’s disease motor progression in the open-label extension of the PASADENA trial
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    nature.com/articles/s41591-024-03270-6
  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Exploring the Potential Imaging Biomarkers for Parkinson’s Disease Using Machine Learning Approach
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    pmc.ncbi.nlm.nih.gov/articles/PMC11762086/
  60. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dopaminergic PET to SPECT domain adaptation: a cycle GAN translation approach
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    pmc.ncbi.nlm.nih.gov/articles/PMC11754385/
  61. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Impact of dopamine deficiency and REM sleep behavior disorder on cognition in early neuronal synuclein disease with hyposmia
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    pmc.ncbi.nlm.nih.gov/articles/PMC11661337/
  62. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Brain age in genetic and idiopathic Parkinson's disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11660940/
  63. 52.53.155.43 52.53.155.43
    PDF-html.html
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    52.53.155.43/04879393ca39922a7c00ba26ca5d51a54504677a/PDF-html.html
  64. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Machine Learning Recognizes Stages of Parkinson’s Disease Using Magnetic Resonance Imaging
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    pmc.ncbi.nlm.nih.gov/articles/PMC11679256/
  65. link.springer.com link.springer.com
    Parkinson’s disease subtypes and their association with probable rapid eye movement sleep behavior disorder severity: a brainstem tractography and machine learning investigation
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    link.springer.com/article/10.1007/s11682-024-00956-w
  66. Dec 2024
  67. www.medrxiv.org www.medrxiv.org
    Subregional analysis of the amygdala, thalamus, and hypothalamus at the pre-decline stage in Parkinson’s disease groups with later cognitive impairment
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    medrxiv.org/content/10.1101/2024.12.18.24319260v1
  68. 52.53.155.43 52.53.155.43
    PDF-html.html
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    52.53.155.43/fce3290c43d12dc82717a7106ed7e9afc85291f9/PDF-html.html
  69. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Decreased SNCA Expression in Whole-Blood RNA Analysis of Parkinson’s Disease Adjusting for Lymphocytes
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    pmc.ncbi.nlm.nih.gov/articles/PMC11601380/
  70. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Approximating R1 and R2: A Quantitative Approach to Clinical Weighted MRI
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    pmc.ncbi.nlm.nih.gov/articles/PMC11656103/
  71. link.springer.com link.springer.com
    Cerebrospinal fluid tau and disease progression in early Parkinson’s disease: an 8-year longitudinal study
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    link.springer.com/article/10.1007/s00415-024-12856-6
  72. www.medrxiv.org www.medrxiv.org
    The genetic architecture of gene expression in individuals of African and European ancestry
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    medrxiv.org/content/10.1101/2024.12.13.24318019v1
  73. www.sciencedirect.com www.sciencedirect.com
    Structural changes in early-stage Parkinson’s disease with resting tremor at node, edge and network level
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    sciencedirect.com/science/article/pii/S0361923024003034
  74. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Blood‐based multivariate methylation risk score for cognitive impairment and dementia
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    pmc.ncbi.nlm.nih.gov/articles/PMC11633365/
  75. www.sciencedirect.com www.sciencedirect.com
    Neuroanatomical heterogeneity drives divergent cognitive and motor trajectories in Parkinson's disease subtypes
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    sciencedirect.com/science/article/pii/S0022510X24004714
  76. Nov 2024
  77. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Longitudinal decline in DAT binding in Parkinson’s disease: connections with sleep disturbances
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    pmc.ncbi.nlm.nih.gov/articles/PMC11583529/
  78. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Comparing machine learning and deep learning models to predict cognition progression in Parkinson's disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11544638/
  79. www.sciencedirect.com www.sciencedirect.com
    A prediction model for the walking and balance milestone in Parkinson's disease
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    sciencedirect.com/science/article/pii/S1353802024011878
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SNPs in cytochromes P450 catalyzing cholesterol degradation in brain are associated with Parkinson’s disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC11472000/
  81. Oct 2024
  82. www.sciencedirect.com www.sciencedirect.com
    Temporal evolution of microstructural integrity in cerebellar peduncles in Parkinson’s disease: Stage-specific patterns and dopaminergic correlates
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    sciencedirect.com/science/article/pii/S2213158224001207
  83. www.medrxiv.org www.medrxiv.org
    Language Modeling Screens Parkinson’s Disease with Self-reported Questionnaires
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    medrxiv.org/content/10.1101/2024.09.23.24314200v1
  84. www.medrxiv.org www.medrxiv.org
    Patient-centered Transcriptomic and Multimodal Neuroimaging Determinants of Clinical Progression, Physical Activity and Treatment Needs in Parkinson’s Disease
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    medrxiv.org/content/10.1101/2024.09.25.24314374v1
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Surface‐Based Morphometry Analysis of the Cerebral Cortex in Patients With Probable Idiopathic Rapid Eye Movement Sleep Behavior Disorder
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    ncbi.nlm.nih.gov/pmc/articles/PMC11440017/
  86. link.springer.com link.springer.com
    Impact of excessive daytime sleepiness on the progression of freezing of gait in de novo Parkinson’s disease: a cohort study
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    link.springer.com/article/10.1007/s10072-024-07738-8
  87. Sep 2024
  88. www.medrxiv.org www.medrxiv.org
    Pesticides and lifestyle factors are associated with disease severity of Parkinson’s disease: a longitudinal study
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    medrxiv.org/content/10.1101/2024.09.06.24313168v1
  89. www.medrxiv.org www.medrxiv.org
    Digital risk score sensitively identifies presence of α-synuclein aggregation or dopaminergic deficit
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    medrxiv.org/content/10.1101/2024.09.05.24313156v1
  90. mentalhealth.bmj.com mentalhealth.bmj.com
    Parkinson’s disease psychosis associated with accelerated multidomain cognitive decline
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    mentalhealth.bmj.com/content/27/1/e301062
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Shared and distinct cortical morphometric alterations in five neuropsychiatric symptoms of Parkinson’s disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC11364691/
  92. Aug 2024
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Exposure to household pesticides and Parkinson's disease in the Parkinson's Progression Markers Initiative cohort
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    ncbi.nlm.nih.gov/pmc/articles/PMC11346339/
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MRI subtypes in Parkinson’s disease across diverse populations and clustering approaches
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    ncbi.nlm.nih.gov/pmc/articles/PMC11329719/
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Predicting Cerebrospinal Fluid Alpha-Synuclein Seed Amplification Assay Status from Demographics and Clinical Data
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    ncbi.nlm.nih.gov/pmc/articles/PMC11326325/
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Long-Term Dementia Risk in Parkinson Disease
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  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  104. Jul 2024
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  120. Jun 2024
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  125. May 2024
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  133. Apr 2024
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  142. Mar 2024
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  146. Feb 2024
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  160. Dec 2023
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  163. Nov 2023
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  169. Oct 2023
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  176. Sep 2023
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  184. Aug 2023
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  188. Jul 2023
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  191. Jun 2023
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  195. Jan 2023
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  197. Aug 2022
  198. www.sciencedirect.com www.sciencedirect.com
    Uncertainty-driven ensembles of multi-scale deep architectures for image classification
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    sciencedirect.com/science/article/pii/S1566253522001038
  199. Jul 2022
  200. www.medrxiv.org www.medrxiv.org
    An MRI-based Deep Learning Model to Predict Parkinson’s Disease Stages
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    medrxiv.org/content/10.1101/2021.02.19.21252081v1
  201. Apr 2022
  202. link.springer.com link.springer.com
    Machine Learning Based Approaches in the Detection of Parkinson’s Disease – A Comparative Study
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    link.springer.com/chapter/10.1007/978-981-19-1677-9_68
  203. Apr 2021
  204. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Characterizing resting‐state networks in Parkinson’s disease: A multi‐aspect functional connectivity study
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    onlinelibrary.wiley.com/doi/10.1002/brb3.2101
  205. Jan 2020
  206. www.frontiersin.org www.frontiersin.org
    Parkinson's Disease Detection Using Isosurfaces-Based Features and Convolutional Neural Networks
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    frontiersin.org/articles/10.3389/fninf.2019.00048/full
  207. Nov 2018
  208. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Untitled document
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    onlinelibrary.wiley.com/doi/full/10.1002/brb3.1073