449 Matching Annotations
  1. Feb 2022
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The ratio of toxic-to-nontoxic microRNAs predicts platinum sensitivity in ovarian cancer
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    1. scibot 02 Feb 2022
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      DOI: 10.1158/0008-5472.CAN-21-0953

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    ncbi.nlm.nih.gov/pmc/articles/PMC8338879/
  3. Jan 2022
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    iMyoblasts for ex vivo and in vivo investigations of human myogenesis and disease modeling
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    1. scibot 29 Jan 2022
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      DOI: 10.7554/eLife.70341

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    ncbi.nlm.nih.gov/pmc/articles/PMC8789283/
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Estimated Renal Metabolomics at Reperfusion Predicts One-Year Kidney Graft Function
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    1. scibot 26 Jan 2022
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      DOI: 10.3390/metabo12010057

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    ncbi.nlm.nih.gov/pmc/articles/PMC8778290/
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Heat shock factor 1 (HSF1) cooperates with estrogen receptor α (ERα) in the regulation of estrogen action in breast cancer cells
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    1. scibot 07 Jan 2022
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      DOI: 10.7554/eLife.69843

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    ncbi.nlm.nih.gov/pmc/articles/PMC8709578/
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulatory T cell transcriptomic reprogramming characterizes adverse events by checkpoint inhibitors in solid tumors
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    1. scibot 05 Jan 2022
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      DOI: 10.1158/2326-6066.CIR-20-0969

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    ncbi.nlm.nih.gov/pmc/articles/PMC7611354/
  8. Dec 2021
  9. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Transcriptome analysis reveals the contribution of oligodendrocyte and radial glia-derived cues for maintenance of microglia identity
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      DOI: 10.1002/glia.24136

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    onlinelibrary.wiley.com/doi/10.1002/glia.24136
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Effect of miR-183-5p on Cholestatic Liver Fibrosis by Regulating Fork Head Box Protein O1 Expression
    1
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      DOI: 10.3389/fphys.2021.737313

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    ncbi.nlm.nih.gov/pmc/articles/PMC8639207/
  11. www.sciencedirect.com www.sciencedirect.com
    Pre-existing chromatin accessibility and gene expression differences among naive CD4+ T cells influence effector potential
    1
    1. scibot 01 Dec 2021
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    sciencedirect.com/science/article/pii/S2211124721015503
  12. Nov 2021
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    Prenatal interleukin 6 elevation increases glutamatergic synapse density and disrupts hippocampal connectivity in offspring
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    sciencedirect.com/science/article/pii/S107476132100412X
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    Attention to time-of-day variability improves the reproducibility of gene expression patterns in multiple sclerosis
    1
    1. scibot 09 Nov 2021
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    sciencedirect.com/science/article/pii/S2589004221012165
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Disrupted PGR-B and ESR1 signaling underlies defective decidualization linked to severe preeclampsia
    1
    1. scibot 05 Nov 2021
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      DOI: 10.7554/eLife.70753

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    ncbi.nlm.nih.gov/pmc/articles/PMC8553341/
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    Patch-seq of mouse DRG neurons reveals candidate genes for specific mechanosensory functions
    1
    1. scibot 03 Nov 2021
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    sciencedirect.com/science/article/pii/S2211124721013875
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    Acute depletion of the ARID1A subunit of SWI/SNF complexes reveals distinct pathways for activation and repression of transcription
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    1. scibot 03 Nov 2021
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      DOI: 10.1016/j.celrep.2021.109943

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    sciencedirect.com/science/article/pii/S2211124721014169
  18. Oct 2021
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    Acrylamide modulates the mouse epididymal proteome to drive alterations in the sperm small non-coding RNA profile and dysregulate embryo development
    1
    1. scibot 06 Oct 2021
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    sciencedirect.com/science/article/pii/S2211124721012468
  20. Sep 2021
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Monocytic differentiation and AHR signaling as Primary Nodes of BET Inhibitor Response in Acute Myeloid Leukemia
    1
    1. scibot 28 Sep 2021
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      DOI: 10.1158/2643-3230.bcd-21-0012

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    ncbi.nlm.nih.gov/pmc/articles/PMC8462123/
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Subventricular zone/white matter microglia reconstitute the empty adult microglial niche in a dynamic wave
    1
    1. scibot 14 Sep 2021
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      DOI: 10.7554/eLife.66738

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  23. Aug 2021
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    Pro-inflammatory β cell small extracellular vesicles induce β cell failure through activation of the CXCL10/CXCR3 axis in diabetes
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    1. scibot 25 Aug 2021
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      DOI: 10.1016/j.celrep.2021.109613

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    sciencedirect.com/science/article/pii/S2211124721010512
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    Epigenomic and transcriptional profiling identifies impaired glyoxylate detoxification in NAFLD as a risk factor for hyperoxaluria
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      DOI: 10.1016/j.celrep.2021.109526

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    sciencedirect.com/science/article/pii/S2211124721009578
  26. journals.sagepub.com journals.sagepub.com
    SAGE Journals: Your gateway to world-class research journals
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    1. scibot 13 Aug 2021
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      DOI: 10.1177/1759091419843393

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    journals.sagepub.com/doi/full/10.1177/1759091419843393
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Polycomb-Dependent Epigenome Controls β Cell Dysfunction, Dedifferentiation, and Diabetes
    1
    1. scibot 12 Aug 2021
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      DOI: 10.1016/j.cmet.2018.04.013

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    ncbi.nlm.nih.gov/pmc/articles/PMC5989056/
  28. elifesciences.org elifesciences.org
    Evolution of reduced co-activator dependence led to target expansion of a starvation response pathway
    1
    1. scibot 12 Aug 2021
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      DOI: 10.7554/eLife.25157

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    elifesciences.org/articles/25157
  29. www.eneuro.org www.eneuro.org
    Untitled document
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    1. scibot 11 Aug 2021
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      DOI: 10.1523/ENEURO.0320-18.2018

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    eneuro.org/content/5/6/ENEURO.0320-18.2018
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    1. scibot 09 Aug 2021
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      DOI: 10.7554/eLife.38675

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    ncbi.nlm.nih.gov/pmc/articles/PMC6224195/
  31. www.ncbi.nlm.nih.govhttp: www.ncbi.nlm.nih.govhttp:
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      DOI: 10.1038/s41598-018-29993-4

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    ncbi.nlm.nih.govhttp://europepmc.org/articles/PMC6070528/
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sex‐dependent and sex‐independent regulatory systems of size variation in natural populations
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      DOI: 10.15252/msb.20199012

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    ncbi.nlm.nih.gov/pmc/articles/PMC6878047/
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A 5‐gene prognostic nomogram predicting survival probability of glioblastoma patients
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      DOI: 10.1002/brb3.1258

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    ncbi.nlm.nih.gov/pmc/articles/PMC6456771/
  34. www.sciencedirect.com www.sciencedirect.com
    DUX4-Induced Histone Variants H3.X and H3.Y Mark DUX4 Target Genes for Expression
    1
    1. scibot 01 Aug 2021
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      DOI: 10.1016/j.celrep.2019.10.025

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    sciencedirect.com/science/article/pii/S2211124719313257
  35. Jul 2021
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptomic Signatures of Postnatal and Adult Intrinsically Photosensitive Ganglion Cells
    1
    1. scibot 31 Jul 2021
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      DOI: 10.1523/ENEURO.0022-19.2019

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    ncbi.nlm.nih.gov/pmc/articles/PMC6712207/
  37. academic.oup.com academic.oup.com
    Gtf2i and Gtf2ird1 mutation do not account for the full phenotypic effect of the Williams syndrome critical region in mouse models
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    1. scibot 31 Jul 2021
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      DOI: 10.1093/hmg/ddz176

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    academic.oup.com/hmg/advance-article/doi/10.1093/hmg/ddz176/5550314
  38. journals.sagepub.com journals.sagepub.com
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    journals.sagepub.com/doi/abs/10.1177/1759091419843393
  39. onlinelibrary.wiley.com onlinelibrary.wiley.com
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  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6361723/
  41. academic.oup.com academic.oup.com
    HUMAN TROPHOBLAST DIFFERENTIATION IS ASSOCIATED WITH PROFOUND GENE REGULATORY AND EPIGENETIC CHANGES
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      DOI: 10.1210/en.2019-00144

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    academic.oup.com/endo/article-abstract/160/9/2189/5530214
  42. www.embopress.org www.embopress.org
    CDK12 drives breast tumor initiation and trastuzumab resistance via WNT and IRS1‐ErbB‐PI3K signaling
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      DOI: 10.15252/embr.201948058

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  43. elifesciences.org elifesciences.org
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  44. elifesciences.org elifesciences.org
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      DOI: 10.7554/eLife.26876

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  45. www.sciencedirect.com www.sciencedirect.com
    Targeting CDK9 Reactivates Epigenetically Silenced Genes in Cancer
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      DOI: 10.1016/j.cell.2018.09.051

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    sciencedirect.com/science/article/pii/S0092867418312637
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    Chromatin Environment and Cellular Context Specify Compensatory Activity of Paralogous MEF2 Transcription Factors
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    sciencedirect.com/science/article/pii/S2211124719313336
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    DUX4-Induced Histone Variants H3.X and H3.Y Mark DUX4 Target Genes for Expression
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    sciencedirect.com/science/article/pii/S2211124719313257
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    Modulation of Microglia by Voluntary Exercise or CSF1R Inhibition Prevents Age-Related Loss of Functional Motor Units
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    sciencedirect.com/science/article/pii/S2211124719312963
  49. www.frontiersin.org www.frontiersin.org
    Understanding the Mechanistic Contribution of Herbal Extracts in Compound Kushen Injection With Transcriptome Analysis
    1
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      DOI: 10.3389/fonc.2019.00632

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    frontiersin.org/articles/10.3389/fonc.2019.00632/full
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic interactions of G-quadruplexes in humans
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      DOI: 10.7554/eLife.46793

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    AGO CLIP Reveals an Activated Network for Acute Regulation of Brain Glutamate Homeostasis in Ischemic Stroke
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    Antagonizing Increased miR-135a Levels at the Chronic Stage of Experimental TLE Reduces Spontaneous Recurrent Seizures
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    PI3K Inhibition Activates SGK1 via a Feedback Loop to Promote Chromatin-Based Regulation of ER-Dependent Gene Expression
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    DNA Hypermethylation Encroachment at CpG Island Borders in Cancer Is Predisposed by H3K4 Monomethylation Patterns
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    Molecular Profiling Defines Evolutionarily Conserved Transcription Factor Signatures of Major Vestibulospinal Neuron Groups
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    MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis
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    Ezh2 and Runx1 Mutations Collaborate to Initiate Lympho-Myeloid Leukemia in Early Thymic Progenitors
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    Transcriptome profiling of developing photoreceptor subtypes reveals candidate genes involved in avian photoreceptor diversification
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    Phenotypic Screening Following Transcriptomic Deconvolution to Identify Transcription Factors Mediating Axon Growth Induced by a Kinase Inhibitor - Jeffrey A. Lowell, Nicholas O’Neill, Matt C. Danzi, Hassan Al-Ali, John L. Bixby, Vance P. Lemmon, 2021
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    Development and Characterization of Novel Endoxifen-Resistant Breast Cancer Cell Lines Highlight Numerous Differences from Tamoxifen-Resistant Models
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    Monocytic Ontogeny of Regenerated Macrophages Characterizes the Mesotheliomagenic Responses to Carbon Nanotubes
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    Omics Profiling of S2P Mutant Fibroblasts as a Mean to Unravel the Pathomechanism and Molecular Signatures of X-Linked MBTPS2 Osteogenesis Imperfecta
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    Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonist
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    Stem-like cells drive NF1-associated MPNST functional heterogeneity and tumor progression
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    Cadherin 11 Promotes Immunosuppression and Extracellular Matrix Deposition to Support Growth of Pancreatic Tumors and Resistance to Gemcitabine in Mice
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    Adult Neural Stem Cells Are Alerted by Systemic Inflammation through TNF-α Receptor Signaling
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    Transcriptional Programs of Circuit Assembly in the Drosophila Visual System
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    SAFB2 Enables the Processing of Suboptimal Stem-Loop Structures in Clustered Primary miRNA Transcripts
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    Shedding Light on the Dynamic Role of the “Target of Rapamycin” Kinase in the Fast-Growing C4 Species Setaria viridis, a Suitable Model for Biomass Crops
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    Pathological angiogenesis in retinopathy engages cellular senescence and is amenable to therapeutic elimination via BCL-xL inhibition
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  94. Apr 2021
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    Erosion of human X chromosome inactivation causes major remodeling of the iPSC proteome
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    Tissue-specific modulation of gene expression in response to lowered insulin signalling in Drosophila
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    Immunogenomic Landscape of Hematological Malignancies
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    Early stem cell aging in the mature brain
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    BET Inhibition Blocks Inflammation-Induced Cardiac Dysfunction and SARS-CoV-2 Infection
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  100. Mar 2021
  101. onlinelibrary.wiley.com onlinelibrary.wiley.com
    A Ketogenic Diet Differentially Affects Neuron And Astrocyte Transcription
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  102. elifesciences.org elifesciences.org
    One-shot analysis of translated mammalian lncRNAs with AHARIBO
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    Mapping immune variation and var gene switching in naive hosts infected with Plasmodium falciparum
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  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Zinc Finger Protein CTCF Regulates Extracellular Matrix (ECM)-Related Gene Expression Associated With the Wnt Signaling Pathway in Gastric Cancer
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    Convergent organization of aberrant MYB complex controls oncogenic gene expression in acute myeloid leukemia
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  106. Feb 2021
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    Vitamin D-regulated gene expression profiles: species-specificity and cell-specific effects on metabolism and immunity
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    Def6 regulates endogenous type-I interferon responses in osteoblasts and suppresses osteogenesis
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    The Parkinson's disease–associated kinase LRRK2 regulates genes required for cell adhesion, polarization, and chemotaxis in activated murine macrophages
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    Identification of regenerative processes in neonatal spinal cord injury in the opossum (Monodelphis domestica), a transcriptomic study
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    Zebrafish macrophage developmental arrest underlies depletion of microglia and reveals Csf1r-independent metaphocytes
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    The corepressors GPS2 and SMRT control enhancer and silencer remodeling via eRNA transcription during inflammatory activation of macrophages
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    Evaluating the genome and resistome of extensively drug-resistant Klebsiella pneumoniae using native DNA and RNA Nanopore sequencing
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    PDA Indolylmaleimides Induce Anti-Tumor Effects in Prostate Carcinoma Cell Lines Through Mitotic Death
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  115. Jan 2021
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    Loss of Parkinson’s susceptibility gene LRRK2 promotes carcinogen-induced lung tumorigenesis
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  117. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Failures of nerve regeneration caused by aging or chronic denervation are rescued by restoring Schwann cell c-Jun
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  118. academic.oup.com academic.oup.com
    A chromosome-level genome assembly of the oriental river prawn, Macrobrachium nipponense
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  119. Dec 2020
  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Optogenetic investigation of BMP target gene expression diversity
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  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-cell multiomic profiling of human lungs reveals cell-type-specific and age-dynamic control of SARS-CoV2 host genes
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  122. Nov 2020
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    Original research: Long-term survival of patients with stage III colon cancer treated with VRP-CEA(6D), an alphavirus vector that increases the CD8+ effector memory T cell to Treg ratio
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  124. www.sciencedirect.com www.sciencedirect.com
    Ablation of Fat Cells in Adult Mice Induces Massive Bone Gain
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  125. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    M. tuberculosis Reprograms Hematopoietic Stem Cells to Limit Myelopoiesis and Impair Trained Immunity
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  126. Oct 2020
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    Host-induced spermidine production in motile Pseudomonas aeruginosa triggers phagocytic uptake
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  128. Sep 2020
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    Sphingosine 1-phosphate-regulated transcriptomes in heterogenous arterial and lymphatic endothelium of the aorta
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    Non-Canonical Caspase Activity Antagonizes p38 MAPK Stress-Priming Function to Support Development
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    Genome-Scale CRISPR Screening in Human Intestinal Organoids Identifies Drivers of TGF-β Resistance
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    Symmetric Arginine Dimethylation Is Selectively Required for mRNA Splicing and the Initiation of Type I and Type III Interferon Signaling
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    De novo genome assembly and Hi-C analysis reveal an association between chromatin architecture alterations and sex differentiation in the woody plant Jatropha curcas
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    Maturational Changes in Mouse Cutaneous Touch and Piezo2-Mediated Mechanotransduction
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    Combined Targeting of Estrogen Receptor Alpha and Exportin 1 in Metastatic Breast Cancers
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    Cell-type diversity and regionalized gene expression in the planarian intestine
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  137. www.frontiersin.org www.frontiersin.org
    Time-Course RNAseq Reveals Exserohilum turcicum Effectors and Pathogenicity Determinants
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    De novo Assembly of Transcriptomes From a B73 Maize Line Introgressed With a QTL for Resistance to Gray Leaf Spot Disease Reveals a Candidate Allele of a Lectin Receptor-Like Kinase
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    Osterix-Cre marks distinct subsets of CD45- and CD45+ stromal populations in extra-skeletal tumors with pro-tumorigenic characteristics
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    An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates
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    Failed Apoptosis Enhances Melanoma Cancer Cell Aggressiveness
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    Genome and population sequencing of a chromosome-level genome assembly of the Chinese tapertail anchovy ( Coilia nasus ) provides novel insights into migratory adaptation
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    Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS
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    Pharmacological Induction of RAS-GTP Confers RAF Inhibitor Sensitivity in KRAS Mutant Tumors
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    Dynamic Human Environmental Exposome Revealed by Longitudinal Personal Monitoring
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    LC3-Associated Phagocytosis in Myeloid Cells Promotes Tumor Immune Tolerance
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    Suppression of Plant Immunity by Fungal Chitinase-like Effectors
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    Single Cell and Open Chromatin Analysis Reveals Molecular Origin of Epidermal Cells of the Skin
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    Disruption of the β1L Isoform of GABP Reverses Glioblastoma Replicative Immortality in a TERT Promoter Mutation-Dependent Manner
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    Small Molecule Targeting of Specific BAF (mSWI/SNF) Complexes for HIV Latency Reversal
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  192. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Neuronal activity induces glutathione metabolism gene expression in astrocytes
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    Lung γδ T Cells Mediate Protective Responses during Neonatal Influenza Infection that Are Associated with Type 2 Immunity
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    Quiescent Endothelial Cells Upregulate Fatty Acid β-Oxidation for Vasculoprotection via Redox Homeostasis
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    Transcription Elongation Can Affect Genome 3D Structure
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    Dismissal of RNA Polymerase II Underlies a Large Ligand-Induced Enhancer Decommissioning Program
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    Architectural Proteins and Pluripotency Factors Cooperate to Orchestrate the Transcriptional Response of hESCs to Temperature Stress
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    APD-Containing Cyclolipodepsipeptides Target Mitochondrial Function in Hypoxic Cancer Cells
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    Pseudouridylation of tRNA-Derived Fragments Steers Translational Control in Stem Cells
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    Cooperative Metabolic Adaptations in the Host Can Favor Asymptomatic Infection and Select for Attenuated Virulence in an Enteric Pathogen
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  201. www.nature.com www.nature.com
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    Decoupling Yeast Cell Division and Stress Defense Implicates mRNA Repression in Translational Reallocation during Stress
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    Sensory Neuron Diversity in the Inner Ear Is Shaped by Activity
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    Hyaluronan Receptor LYVE-1-Expressing Macrophages Maintain Arterial Tone through Hyaluronan-Mediated Regulation of Smooth Muscle Cell Collagen
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    Diet-Induced Circadian Enhancer Remodeling Synchronizes Opposing Hepatic Lipid Metabolic Processes
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    Biology and Clinical Implications of the 19q13 Aggressive Prostate Cancer Susceptibility Locus
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    EZH2-Mediated Primary Cilium Deconstruction Drives Metastatic Melanoma Formation
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    Evidence for a Non-leptin System that Defends against Weight Gain in Overfeeding
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    Stable STIM1 Knockdown in Self-Renewing Human Neural Precursors Promotes Premature Neural Differentiation
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    Multiscale Analysis of Independent Alzheimer’s Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus
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    Inhibition of Methyltransferase Setd7 Allows the In Vitro Expansion of Myogenic Stem Cells with Improved Therapeutic Potential
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    Ultraconserved Enhancers Are Required for Normal Development
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    Arabidopsis Serrate Coordinates Histone Methyltransferases ATXR5/6 and RNA Processing Factor RDR6 to Regulate Transposon Expression
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    Hemodynamic Forces Sculpt Developing Heart Valves through a KLF2-WNT9B Paracrine Signaling Axis
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    Reactive Neutrophil Responses Dependent on the Receptor Tyrosine Kinase c-MET Limit Cancer Immunotherapy
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    Developmental Origin Governs CD8+ T Cell Fate Decisions during Infection
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    JMJD6 Licenses ERα-Dependent Enhancer and Coding Gene Activation by Modulating the Recruitment of the CARM1/MED12 Co-activator Complex
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    sciencedirect.com/science/article/pii/S1097276518301874
  219. www.jneurosci.org www.jneurosci.org
    mTORC1 Is Transiently Reactivated in Injured Nerves to Promote c-Jun Elevation and Schwann Cell Dedifferentiation
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    jneurosci.org/content/38/20/4811