1,280 Matching Annotations
  1. Jun 2025
  2. www.sciencedirect.com www.sciencedirect.com
    ChemPerturb-seq screen identifies a small molecule cocktail enhancing human beta cell survival after subcutaneous transplantation
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    sciencedirect.com/science/article/pii/S1934590925002243
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    An organ-chip model of sporadic ALS using iPSC-derived spinal cord motor neurons and an integrated blood-brain-like barrier
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    sciencedirect.com/science/article/pii/S193459092500222X
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    Neurodevelopmental hijacking of oligodendrocyte lineage programs drives glioblastoma infiltration
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    cell.com/developmental-cell/abstract/S1534-5807(25)00260-6
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    Protocol for sex-specific isolation of microglia, oligodendrocyte precursor cells, and astrocytes from neonatal rats using shake-off technique
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    sciencedirect.com/science/article/pii/S2666166725003089
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    A hexamer tandem repeat RNA embedded within an SVA retrotransposon drives R-loop formation and neurodegeneration
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    PRPS activity tunes redox homeostasis in Myc-driven lymphoma
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    Piezo1 senses hyphae and initiates host defense against pathogenic fungi
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    Identification of key genes regulating brown adipose tissue thermogenesis in goat kids (Capra hircus) by using weighted gene co-expression network analysis
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    Restoration of the Tumor Suppressor Function of Y220C-Mutant p53 by Rezatapopt, a Small-Molecule Reactivator
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    Increasing Stemness Drives Prostate Cancer Progression, Plasticity, Therapy Resistance and Poor Patient Survival
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    Proliferating Microglia Exhibit Unique Transcriptional and Functional Alterations in Alzheimer’s Disease
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    Chromosome-level reference genome for the medically important Arabian horned viper (Cerastes gasperettii)
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    Cholesterol metabolism regulated by CAMKK2-CREB signaling promotes castration-resistant prostate cancer
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    Screening a living biobank identifies cabazitaxel as a strategy to combat acquired taxol resistance in high-grade serous ovarian cancer
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  22. May 2025
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A bacterial regulatory uORF senses multiple classes of ribosome-targeting antibiotics
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    Microbial cancer immunotherapy reprograms hematopoiesis to enhance myeloid-driven anti-tumor immunity
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    Pharmacologic ascorbate resistant pancreatic cancer demonstrates enhanced metastatic potential
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    Microglia aging in the hippocampus advances through intermediate states that drive activation and cognitive decline
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    Transcriptome profiling of tendon fibroblasts at the onset of embryonic muscle contraction reveals novel force-responsive genes
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    SMIM20 promotes complex IV biogenesis and Ca2+ signaling in mice heart
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  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    High-resolution transcriptional impact of AIRE: effects of pathogenic variants p.Arg257Ter, p.Cys311Tyr, and polygenic risk variant p.Arg471Cys
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    Improvement in the function of self-activating chimeric antigen receptor by replacing the linker sequence
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    Clear-Cell Renal Cell Carcinoma Molecular Subtypes Differ by African and European Genetic Similarity
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    Convergent Genetic Adaptation in Human Tumors Developed Under Systemic Hypoxia and in Populations Living at High Altitudes
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    Targeting Ovarian Cancer Stem Cells by Dual Inhibition of the Long Noncoding RNA HOTAIR and Lysine Methyltransferase EZH2
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    Genetic Screen in a Pre-Clinical Model of Sarcoma Development Defines Drivers and Therapeutic Vulnerabilities
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    Intratumoral Fusobacterium nucleatum Recruits Tumor-Associated Neutrophils to Promote Gastric Cancer Progression and Immune Evasion
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    Memory T‐Cell Phenotype in Cutaneous T‐Cell Lymphoma Is Modified by Germline Gene Gametocyte Specific Factor 1
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    Complete Loss of PAX4 causes Transient Neonatal Diabetes in Humans
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    Impact of ATF6 deletion on the embryonic brain development
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    The haplotype-resolved T2T genome for Bauhinia × blakeana sheds light on the genetic basis of flower heterosis
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    MCRS1 sensitizes T cell–dependent immunotherapy by augmenting MHC-I expression in solid tumors
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    Avelumab induces greater Fc-Fc receptor-dependent natural killer cell activation and dendritic cell crosstalk compared to durvalumab
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    Tumor break load quantitates structural variant-associated genomic instability with biological and clinical relevance across cancers
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    DNA methyltransferase 1 modulates mitochondrial function through bridging m5C RNA methylation
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    Direct microglia replacement reveals pathologic and therapeutic contributions of brain macrophages to a monogenic neurological disease
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    Repeat-element RNAs integrate a neuronal growth circuit
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    Genetic modeling of ELP1-associated Sonic hedgehog medulloblastoma identifies MDM2 as a selective therapeutic target
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    Mitochondrial fatty acid oxidation regulates adult muscle stem cell function through modulating metabolic flux and protein acetylation
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    Peroxisomes are critical for a unique metabolic demand and survival of alveolar macrophages
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    High expression of THY1 is a prognostic marker for gastric Cancer: Deciphering its transcriptional regulation as a component of the Epithelial–mesenchymal transition
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  53. Apr 2025
  54. www.nature.com www.nature.com
    α-Ketoglutarate promotes trophectoderm induction and maturation from naive human embryonic stem cells
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    LncRNA SLNCR phenocopies the E2F1 DNA binding site to promote melanoma progression
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    Global changes in Staphylococcus aureus virulence and metabolism during colonization of healthy skin
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    The SWI/SNF PBAF complex facilitates REST occupancy at repressive chromatin
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  58. aacrjournals.org aacrjournals.org
    A Phase II Study of Abemaciclib for Patients with Retinoblastoma-Positive, Metastatic Triple-Negative Breast Cancer
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    The Prostaglandin EP4 Antagonist Vorbipiprant Combined with PD-1 Blockade for Refractory Microsatellite Stable Metastatic Colorectal Cancer: A Phase 1b/2a Trial
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    Phase 1/2 trial of XPO1 inhibitor selinexor plus docetaxel in previously treated, advanced KRAS mutant non-small cell lung cancer
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    Enteric glia regulate Paneth cell secretion and intestinal microbial ecology
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    The multi-level effect of chlorpyrifos during clownfish metamorphosis
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    KRIT1 heterozygous mutations are sufficient to induce a pathological phenotype in patient-derived iPSC models of cerebral cavernous malformation
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    YTHDC2 serves a distinct late role in spermatocytes during germ cell differentiation
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    Intestinal secretory differentiation reflects niche-driven phenotypic and epigenetic plasticity of a common signal-responsive terminal cell
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    Early Neutrophil Activation in Psoriatic Skin at Relapse Following Dead Sea Climatotherapy
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    CD103+CD56+ ILCs Are Associated with an Altered CD8+ T-cell Profile within the Tumor Microenvironment
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    Spatially Resolved Tumor Ecosystems and Cell States in Gastric Adenocarcinoma Progression and Evolution
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    Identification of a TNIK-CDK9 Axis as a Targetable Strategy for Platinum-Resistant Ovarian Cancer
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    Sex differences in DNMT3A-mutant clonal hematopoiesis and the effects of estrogen
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    Decoding m6Am by simultaneous transcription-start mapping and methylation quantification
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    Targeting the dendritic cell-secreted immunoregulatory cytokine CCL22 alleviates radioresistance
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    The metabolic sensor LKB1 regulates ILC3 homeostasis and mitochondrial function
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  77. Mar 2025
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    Seeded aggregation of TDP-43 induces its loss of function and reveals early pathological signatures
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    Metallophilic marginal zone macrophages cross-prime CD8+ T cell-mediated protective immunity against blood-borne tumors
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    Lineage contribution of the mesendoderm progenitors in the gastrulating mouse embryo
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    Transcriptome Analysis of Canine Histiocytic Sarcoma Tumors and Cell Lines Reveals Multiple Targets for Therapy
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    Divergent opioid-mediated suppression of inhibition between hippocampus and neocortex across species and development
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    Orchestration of pluripotent stem cell genome reactivation during mitotic exit
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    A niche driven mechanism determines response and a mutation-independent therapeutic approach for myeloid malignancies
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    The domesticated transposon protein L1TD1 associates with its ancestor L1 ORF1p to promote LINE-1 retrotransposition
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    Hi-GDT: A Hi-C-based 3D gene domain analysis tool for analyzing local chromatin contacts in plants
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    The carnosinase dipeptidase CNDP1 is a novel metabolic vulnerability in brain metastasis
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    biorxiv.org/content/10.1101/2025.03.18.644053v1
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    Glucose modulates IRF6 transcription factor dimerization to enable epidermal differentiation
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  177. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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  178. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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  179. www.sciencedirect.com www.sciencedirect.com
    Type III interferons induce pyroptosis in gut epithelial cells and impair mucosal repair
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  180. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Preclinical Multi-Omic Assessment of Pioglitazone in Skeletal Muscles of Mice Implanted with Human HER2/neu Overexpressing Breast Cancer Xenografts
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  181. 52.53.155.43 52.53.155.43
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  182. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    DNAR-05. EXCEPTIONAL RESPONDERS TO BASE EXCISION REPAIR (BER) INHIBITION FOR RECURRENT GLIOBLASTOMA DISPLAY ENRICHMENT FOR DNA DAMAGE RESPONSE PATHWAYS: RNA SEQUENCING ANALYSIS FROM A MULTICENTER TRIAL
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  184. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Molecular basis of neurodegeneration in a mouse model of Polr3-related disease
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  186. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Negative cell cycle regulation by calcineurin is necessary for proper beta cell regeneration in zebrafish
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  188. Oct 2024
  189. aacrjournals.org aacrjournals.org
    NK Receptor Signaling Lowers TCR Activation Threshold, Enhancing Selective Recognition of Cancer Cells by TAA-Specific CTLs
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  190. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Quiescence and aging of melanocyte stem cells and a novel association with PD-L1
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  191. aacrjournals.org aacrjournals.org
    RNA sequencing and Immunohistochemistry Reveal ZFN7 as a Stronger Marker of Survival than Molecular Subtypes in G-CIMP–negative Glioblastoma
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    aacrjournals.org/clincancerres/article/27/2/645/83327/RNA-sequencing-and-Immunohistochemistry-Reveal
  192. aacrjournals.org aacrjournals.org
    Systematic Analysis of Intronic miRNAs Reveals Cooperativity within the Multicomponent FTX Locus to Promote Colon Cancer Development
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    H3.3 G34W Promotes Growth and Impedes Differentiation of Osteoblast-Like Mesenchymal Progenitors in Giant Cell Tumor of Bone
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    Glioblastoma TCGA Mesenchymal and IGS 23 Tumors are Identifiable by IHC and have an Immune-phenotype Indicating a Potential Benefit from Immunotherapy
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  195. Sep 2024
  196. www.biorxiv.org www.biorxiv.org
    Integrative multiomic approaches reveal ZMAT3 and p21 as conserved hubs in the p53 tumor suppression network
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    biorxiv.org/content/10.1101/2024.09.17.612743v1
  197. www.biorxiv.org www.biorxiv.org
    Acute increase of protein O-GlcNAcylation in mice leads to transcriptome changes in the brain opposite to what is observed in Alzheimer’s Disease
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    biorxiv.org/content/10.1101/2024.09.19.613769v1
  198. www.sciencedirect.com www.sciencedirect.com
    Single-cell and bulk transcriptional profiling of mouse ovaries reveals novel genes and pathways associated with DNA damage response in oocytes
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  199. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Atypical cellular responses mediated by intracellular constitutive active TrkB (NTRK2) kinase domains and a solely intracellular NTRK2-fusion oncogene
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    The Role of MFN2 in Regulating Endothelial Cell Senescence: Implications for Vascular Aging
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    sciencedirect.com/science/article/pii/S2589004224020340
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    TET2 Regulates the Neuroinflammatory Response in Microglia
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  202. www.biorxiv.org www.biorxiv.org
    Spontaneously regenerative corticospinal neurons in mice
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  203. www.biorxiv.org www.biorxiv.org
    Sex-specific chemosensory gene expression in the whitelined sphinx moth (Lepidoptera: Hyles lineata) suggests a role for odorant-binding proteins in host plant choice
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  204. www.biorxiv.org www.biorxiv.org
    A near-complete genome assembly of the bearded dragon Pogona vitticeps provides insights into the origin of Pogona sex chromosomes
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    biorxiv.org/content/10.1101/2024.09.05.611321v1
  205. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The SWI/SNF PBAF complex facilitates REST occupancy at repressive chromatin
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