1,151 Matching Annotations
  1. Jan 2025
  2. www.sciencedirect.com www.sciencedirect.com
    A cis-regulatory element controls expression of histone deacetylase 9 to fine-tune inflammasome-dependent chronic inflammation in atherosclerosis
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    sciencedirect.com/science/article/pii/S1074761325000263
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Segment specific loss of NFAT5 function in the kidneys is sufficient to induce a global kidney injury like phenotype
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    pmc.ncbi.nlm.nih.gov/articles/PMC11774485/
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A chromosome-scale genome assembly of the pioneer plant Stylosanthes angustifolia: insights into genome evolution and drought adaptation
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    pmc.ncbi.nlm.nih.gov/articles/PMC11758145/
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    Cytoplasmic mRNA decay controlling inflammatory gene expression is determined by pre-mRNA fate decision
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    sciencedirect.com/science/article/pii/S1097276525000012
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Natural killer cell–mediated cytotoxicity shapes the clonal evolution of B cell leukaemia
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    pmc.ncbi.nlm.nih.gov/articles/PMC7617306/
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FOXR2 Targets LHX6+/DLX+ Neural Lineages to Drive Central Nervous System Neuroblastoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11733536/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Brain Transcriptome Changes Associated With an Acute Increase of Protein O‐GlcNAcylation and Implications for Neurodegenerative Disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11741514/
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    Endothelial calcium firing mediates the extravasation of metastatic tumor cells
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    sciencedirect.com/science/article/pii/S2589004224029171
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Antibody-based delivery of interleukin-2 modulates the immunosuppressive tumor microenvironment and achieves cure in pancreatic ductal adenocarcinoma syngeneic mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC11705946/
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    A practical distribution pattern of α-SMA-positive carcinoma associated fibroblasts indicates poor prognosis of patients with pancreatic ductal adenocarcinoma
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    sciencedirect.com/science/article/pii/S1936523325000130
  12. 52.53.155.43 52.53.155.43
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  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    JAK inhibition decreases the autoimmune burden in Down syndrome
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    pmc.ncbi.nlm.nih.gov/articles/PMC11687933/
  14. 52.53.155.43 52.53.155.43
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    Nucleosomal asymmetry shapes histone mark binding and promotes poising at bivalent domains
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    sciencedirect.com/science/article/pii/S1097276524009973
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    1-s2.0-S2589004224027834-main-html.html
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  18. Dec 2024
  19. www.cell.com www.cell.com
    Disrupted methionine cycle triggers muscle atrophy in cancer cachexia through epigenetic regulation of REDD1
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    cell.com/cell-metabolism/fulltext/S1550-4131(24)00413-3
  20. 52.53.155.43 52.53.155.43
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  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    BPDCN MYB fusions regulate cell cycle genes, impair differentiation, and induce myeloid–dendritic cell leukemia
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    pmc.ncbi.nlm.nih.gov/articles/PMC11665559/
  22. www.biorxiv.org www.biorxiv.org
    The gut microbiome promotes mitochondrial respiration in the brain of a Parkinson’s disease mouse model
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    biorxiv.org/content/10.1101/2024.12.18.629251v1
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    3D chromatin hubs as regulatory units of identity and survival in human acute leukemia
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    sciencedirect.com/science/article/pii/S109727652400995X
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pathogenic mitochondrial DNA variants are associated with response to anti-VEGF therapy in ovarian cancer PDX models
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    pmc.ncbi.nlm.nih.gov/articles/PMC11657443/
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    ZNF143 is a transcriptional regulator of nuclear-encoded mitochondrial genes that acts independently of looping and CTCF
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    sciencedirect.com/science/article/pii/S1097276524009560
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    Quantitative profiling of human translation initiation reveals elements that potently regulate endogenous and therapeutically modified mRNAs
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    sciencedirect.com/science/article/pii/S1097276524009559
  27. elifesciences.org elifesciences.org
    Full-length direct RNA sequencing uncovers stress granule-dependent RNA decay upon cellular stress
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    elifesciences.org/articles/96284
  28. elifesciences.org elifesciences.org
    Control of 3′ splice site selection by the yeast splicing factor Fyv6
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    elifesciences.org/articles/100449
  29. 52.53.155.43 52.53.155.43
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    1-s2.0-S2589004224027834-main-html.html
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    Tubulin sequence divergence is associated with the use of distinct microtubule regulators
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    sciencedirect.com/science/article/pii/S096098222401563X
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    Early downmodulation of tumor glycolysis predicts response to fasting-mimicking diet in triple-negative breast cancer patients
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    sciencedirect.com/science/article/pii/S1550413124004509
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    H4K20me3-Mediated Repression of Inflammatory Genes is a Characteristic and Targetable Vulnerability of Persister Cancer Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC7617193/
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Epigenetic and Oncogenic Inhibitors Cooperatively Drive Differentiation and Kill KRAS-Mutant Colorectal Cancers
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    pmc.ncbi.nlm.nih.gov/articles/PMC11609823/
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    Lurbinectedin sensitizes PD-L1 blockade therapy by activating STING-IFN signaling in small-cell lung cancer
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    sciencedirect.com/science/article/pii/S2666379124006232
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    Microglial lipid phosphatase SHIP1 limits complement-mediated synaptic pruning in the healthy developing hippocampus
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    sciencedirect.com/science/article/pii/S1074761324005132
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    Biased signaling by mutant EGFR underlies dependence on PKCα in lung adenocarcinoma
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    sciencedirect.com/science/article/pii/S2211124724013779
  38. www.sciencedirect.com www.sciencedirect.com
    tp53 R217H and R242H mutant zebrafish exhibit dysfunctional p53 hallmarks and recapitulate Li-Fraumeni syndrome phenotypes
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    sciencedirect.com/science/article/pii/S0925443924006069
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    Discovery, Validation and Mechanistic Study of XPO1 Inhibition in the Treatment of Triple-Negative Breast Cancer
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    mdpi.com/2072-6694/16/23/3980
  40. www.science.org www.science.org
    Coordination between the eIF2 kinase GCN2 and p53 signaling supports purine metabolism and the progression of prostate cancer
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    science.org/doi/10.1126/scisignal.adp1375
  41. www.sciencedirect.com www.sciencedirect.com
    The phosphatase PP1 sustains global transcription by promoting RNA polymerase II pause release
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    sciencedirect.com/science/article/pii/S1097276524008852
  42. www.sciencedirect.com www.sciencedirect.com
    Cognate antigen engagement induces HIV-1 expression in latently infected CD4+ T cells from people on long-term antiretroviral therapy
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    sciencedirect.com/science/article/pii/S1074761324005120
  43. www.sciencedirect.com www.sciencedirect.com
    Flt3L enhances clonal diversification and selective expansion of intratumoral CD8+ T cells while differentiating into effector-like cells
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    sciencedirect.com/science/article/pii/S2211124724013743
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    Evolutionary genomics of the emergence of brown algae as key components of coastal ecosystems
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    sciencedirect.com/science/article/pii/S0092867424012728
  45. Nov 2024
  46. gigabytejournal.com gigabytejournal.com
    NeuroVar: an open-source tool for the visualization of gene expression and variation data for biomarkers of neurological diseases
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    gigabytejournal.com/articles/143
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genetic requirement of dact1/2 to regulate noncanonical Wnt signaling and calpain 8 during embryonic convergent extension and craniofacial morphogenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11581427/
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Modeling early phenotypes of Parkinson’s disease by age-induced midbrain-striatum assembloids
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    pmc.ncbi.nlm.nih.gov/articles/PMC11585662/
  49. www.sciencedirect.com www.sciencedirect.com
    Type III interferons induce pyroptosis in gut epithelial cells and impair mucosal repair
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    sciencedirect.com/science/article/pii/S0092867424011589
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Preclinical Multi-Omic Assessment of Pioglitazone in Skeletal Muscles of Mice Implanted with Human HER2/neu Overexpressing Breast Cancer Xenografts
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    pmc.ncbi.nlm.nih.gov/articles/PMC11544806/
  51. 52.53.155.43 52.53.155.43
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  52. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    DNAR-05. EXCEPTIONAL RESPONDERS TO BASE EXCISION REPAIR (BER) INHIBITION FOR RECURRENT GLIOBLASTOMA DISPLAY ENRICHMENT FOR DNA DAMAGE RESPONSE PATHWAYS: RNA SEQUENCING ANALYSIS FROM A MULTICENTER TRIAL
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    pmc.ncbi.nlm.nih.gov/articles/PMC10639771/
  53. 52.53.155.43 52.53.155.43
    mcr-24-0490-html.html
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  54. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Molecular basis of neurodegeneration in a mouse model of Polr3-related disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11537486/
  55. 52.53.155.43 52.53.155.43
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  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Negative cell cycle regulation by calcineurin is necessary for proper beta cell regeneration in zebrafish
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    ncbi.nlm.nih.gov/pmc/articles/PMC11464004/
  57. 52.53.155.43 52.53.155.43
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  58. Oct 2024
  59. aacrjournals.org aacrjournals.org
    NK Receptor Signaling Lowers TCR Activation Threshold, Enhancing Selective Recognition of Cancer Cells by TAA-Specific CTLs
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    aacrjournals.org/cancerimmunolres/article/12/10/1421/748722/NK-Receptor-Signaling-Lowers-TCR-Activation
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Quiescence and aging of melanocyte stem cells and a novel association with PD-L1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11440800/
  61. aacrjournals.org aacrjournals.org
    RNA sequencing and Immunohistochemistry Reveal ZFN7 as a Stronger Marker of Survival than Molecular Subtypes in G-CIMP–negative Glioblastoma
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    aacrjournals.org/clincancerres/article/27/2/645/83327/RNA-sequencing-and-Immunohistochemistry-Reveal
  62. aacrjournals.org aacrjournals.org
    Systematic Analysis of Intronic miRNAs Reveals Cooperativity within the Multicomponent FTX Locus to Promote Colon Cancer Development
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    aacrjournals.org/cancerres/article/81/5/1308/649526/Systematic-Analysis-of-Intronic-miRNAs-Reveals
  63. aacrjournals.org aacrjournals.org
    H3.3 G34W Promotes Growth and Impedes Differentiation of Osteoblast-Like Mesenchymal Progenitors in Giant Cell Tumor of Bone
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    aacrjournals.org/cancerdiscovery/article/10/12/1968/2414/H3-3-G34W-Promotes-Growth-and-Impedes
  64. aacrjournals.org aacrjournals.org
    Glioblastoma TCGA Mesenchymal and IGS 23 Tumors are Identifiable by IHC and have an Immune-phenotype Indicating a Potential Benefit from Immunotherapy
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    aacrjournals.org/clincancerres/article/26/24/6600/82892/Glioblastoma-TCGA-Mesenchymal-and-IGS-23-Tumors
  65. Sep 2024
  66. www.biorxiv.org www.biorxiv.org
    Integrative multiomic approaches reveal ZMAT3 and p21 as conserved hubs in the p53 tumor suppression network
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    biorxiv.org/content/10.1101/2024.09.17.612743v1
  67. www.biorxiv.org www.biorxiv.org
    Acute increase of protein O-GlcNAcylation in mice leads to transcriptome changes in the brain opposite to what is observed in Alzheimer’s Disease
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    biorxiv.org/content/10.1101/2024.09.19.613769v1
  68. www.sciencedirect.com www.sciencedirect.com
    Single-cell and bulk transcriptional profiling of mouse ovaries reveals novel genes and pathways associated with DNA damage response in oocytes
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    sciencedirect.com/science/article/pii/S0012160624002343
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Atypical cellular responses mediated by intracellular constitutive active TrkB (NTRK2) kinase domains and a solely intracellular NTRK2-fusion oncogene
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    ncbi.nlm.nih.gov/pmc/articles/PMC11405271/
  70. www.sciencedirect.com www.sciencedirect.com
    The Role of MFN2 in Regulating Endothelial Cell Senescence: Implications for Vascular Aging
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    sciencedirect.com/science/article/pii/S2589004224020340
  71. www.sciencedirect.com www.sciencedirect.com
    TET2 Regulates the Neuroinflammatory Response in Microglia
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    sciencedirect.com/science/article/pii/S2211124719311908
  72. www.biorxiv.org www.biorxiv.org
    Spontaneously regenerative corticospinal neurons in mice
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    biorxiv.org/content/10.1101/2024.09.09.612115v1
  73. www.biorxiv.org www.biorxiv.org
    Sex-specific chemosensory gene expression in the whitelined sphinx moth (Lepidoptera: Hyles lineata) suggests a role for odorant-binding proteins in host plant choice
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    biorxiv.org/content/10.1101/2024.09.04.611314v1
  74. www.biorxiv.org www.biorxiv.org
    A near-complete genome assembly of the bearded dragon Pogona vitticeps provides insights into the origin of Pogona sex chromosomes
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    biorxiv.org/content/10.1101/2024.09.05.611321v1
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The SWI/SNF PBAF complex facilitates REST occupancy at repressive chromatin
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    ncbi.nlm.nih.gov/pmc/articles/PMC11370600/
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Analysis of miRNAs involved in mouse brain injury upon Coxsackievirus A6 infection
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    ncbi.nlm.nih.gov/pmc/articles/PMC11374775/
  77. www.sciencedirect.com www.sciencedirect.com
    Multiple direct and indirect roles of the Paf1 complex in transcription elongation, splicing, and histone modifications
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    sciencedirect.com/science/article/pii/S2211124724010817
  78. www.sciencedirect.com www.sciencedirect.com
    Targeting EGLN2/PHD1 protects motor neurons and normalizes the astrocytic interferon response
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    sciencedirect.com/science/article/pii/S2211124724010702
  79. www.sciencedirect.com www.sciencedirect.com
    Streamlined regulation of chloroplast development in the liverwort Marchantia polymorpha
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    sciencedirect.com/science/article/pii/S2211124724010477
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multiplexed Spatial Profiling of Hodgkin Reed–Sternberg Cell Neighborhoods in Classic Hodgkin Lymphoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11369618/
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of Aberrantly Overexpressed Polo-like Kinase 4 Is a Potential Effective Treatment for DNA Damage Repair–Deficient Uterine Leiomyosarcoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11369621/
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Detecting Small Cell Transformation in Patients with Advanced EGFR Mutant Lung Adenocarcinoma through Epigenomic cfDNA Profiling
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    ncbi.nlm.nih.gov/pmc/articles/PMC11369616/
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptomic analysis of Asparagus officinalis cultivars with varying levels of freezing tolerance over fall acclimation and spring deacclimation periods
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    ncbi.nlm.nih.gov/pmc/articles/PMC11361922/
  84. www.sciencedirect.com www.sciencedirect.com
    Inhibitory co-receptor Lag3 supports Foxp3+ regulatory T cell function by restraining Myc-dependent metabolic programming
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    sciencedirect.com/science/article/pii/S1074761324004072
  85. Aug 2024
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterizing Relationships between T-cell Inflammation and Outcomes in Patients with High-Risk Neuroblastoma According to Mesenchymal and Adrenergic Signatures
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    ncbi.nlm.nih.gov/pmc/articles/PMC11350481/
  87. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial serine catabolism safeguards maintenance of the hematopoietic stem cell pool in homeostasis and injury
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    sciencedirect.com/science/article/pii/S1934590924002856
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumoral Interferon Beta Induces an Immune-Stimulatory Phenotype in Tumor-Associated Macrophages in Melanoma Brain Metastases
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    ncbi.nlm.nih.gov/pmc/articles/PMC11337092/
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Released bacterial ATP shapes local and systemic inflammation during abdominal sepsis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11335348/
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR screening uncovers a long-range enhancer for ONECUT1 in pancreatic differentiation and links a diabetes risk variant
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  177. www.biorxiv.org www.biorxiv.org
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  180. Apr 2024
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    ER-associated degradation adapter Sel1L is required for CD8+ T cell function and memory formation following acute viral infection
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  183. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  185. aacrjournals.org aacrjournals.org
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  187. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Class I HDAC inhibitors enhance antitumor efficacy and persistence of CAR-T cells by activation of the Wnt pathway
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  197. Mar 2024
  198. www.nature.com www.nature.com
    Clinically-observed FOXA1 mutations upregulate SEMA3C through transcriptional derepression in prostate cancer
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