645 Matching Annotations
  1. May 2025
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    Integrating collecting systems in human kidney organoids through fusion of distal nephron to ureteric bud
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    sciencedirect.com/science/article/pii/S1934590925001432
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    Maternal natural killer cells drive neuroimmune disorders in offspring through aberrant secretion of extracellular granzyme B
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    sciencedirect.com/science/article/pii/S1074761325001918
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    Monocytes can efficiently replace all brain macrophages and fetal liver monocytes can generate bona fide SALL1+ microglia
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    sciencedirect.com/science/article/pii/S1074761325001694
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    Nerve- and airway-associated interstitial macrophages mitigate SARS-CoV-2 pathogenesis via type I interferon signaling
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    sciencedirect.com/science/article/pii/S1074761325001645
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    Direct microglia replacement reveals pathologic and therapeutic contributions of brain macrophages to a monogenic neurological disease
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    Genetic modeling of ELP1-associated Sonic hedgehog medulloblastoma identifies MDM2 as a selective therapeutic target
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    sciencedirect.com/science/article/pii/S1535610825001734
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    MCRS1 sensitizes T cell–dependent immunotherapy by augmenting MHC-I expression in solid tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC11572484/
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    Single-cell transcriptomic profiling reveals diversity in human iNKT cells across hematologic tissues
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    Macrophages direct location-dependent recall of B cell memory to vaccination
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    Immunosequencing identifies signatures of T cell responses for early detection of nasopharyngeal carcinoma
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    Inhibition of autotaxin activity with IOA-289 decreases fibrosis in mouse E0771 breast tumors
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    onlinelibrary.wiley.com/doi/10.1002/ijc.35471
  13. Apr 2025
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    Protocol for characterizing craniopharyngioma subtypes and their microenvironments using single-cell RNA sequencing and immunohistochemistry
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    Ontogeny Dictates Oncogenic Potential, Lineage Hierarchy, and Therapy Response in Pediatric Leukemia
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    MIRO1 mutation leads to metabolic maladaptation resulting in Parkinson’s disease-associated dopaminergic neuron loss
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    link.springer.com/article/10.1038/s41540-025-00509-x
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    Phase 2 trial of perioperative chemo-immunotherapy for gastro-esophageal adenocarcinoma: The role of M2 macrophage landscape in predicting response
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    Intestinal secretory differentiation reflects niche-driven phenotypic and epigenetic plasticity of a common signal-responsive terminal cell
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    Spatially Resolved Tumor Ecosystems and Cell States in Gastric Adenocarcinoma Progression and Evolution
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    Deciphering shared molecular dysregulation across Parkinson’s disease variants using a multi-modal network-based data integration and analysis
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    Sex differences in DNMT3A-mutant clonal hematopoiesis and the effects of estrogen
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    Targeting the dendritic cell-secreted immunoregulatory cytokine CCL22 alleviates radioresistance
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  23. Mar 2025
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    Single-cell transcriptomic and functional studies identify glial state changes and a role for inflammatory RIPK1 signaling in ALS pathogenesis
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    Segregated basal ganglia output pathways correspond to genetically divergent neuronal subclasses
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    The local microenvironment suppresses the synergy between irradiation and anti-PD1 therapy in breast-to-brain metastasis
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    Comparative Single-Cell Transcriptomics of Human Neuroblastoma and Preclinical Models Reveals Conservation of an Adrenergic Cell State
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    Growth of the maternal intestine during reproduction
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    Transcriptomic and Histological Characterization of Telocytes in the Human Dorsal Root Ganglion
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    Impaired yolk sac NAD metabolism disrupts murine embryogenesis with relevance to human birth defects
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    Human brain cell-type-specific aging clocks based on single-nuclei transcriptomics
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    Sensory input, sex and function shape hypothalamic cell type development
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  35. Feb 2025
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    The endogenous antigen-specific CD8+ T cell repertoire is composed of unbiased and biased clonotypes with differential fate commitments
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    Fusion oncoproteins and cooperating mutations define disease phenotypes in NUP98-rearranged leukemia
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    Effect of MisMatch repair deficiency on metastasis occurrence in a syngeneic mouse model
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    Combined forces of hydrostatic pressure and actin polymerization drive endothelial tip cell migration and sprouting angiogenesis
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    CV1-secreting sCAR-T cells potentiate the abscopal effect of microwave ablation in heterogeneous tumors
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    Th17 cells secrete TWEAK to trigger epithelial-mesenchymal transition and promote colorectal cancer liver metastasis
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    Copper Drives Remodeling of Metabolic State and Progression of Clear Cell Renal Cell Carcinoma
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    EMT-driven plasticity prospectively increases cell–cell variability to promote therapeutic adaptation in breast cancer
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    Microglial plasticity governed by state-specific enhancer landscapes
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    Deterministic genetic barcoding for multiplexed behavioral and single-cell transcriptomic studies
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    A developmental atlas of mouse vestibular-like inner ear organoids
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    Myofibroblasts emerge during alveolar regeneration following influenza-virus-induced lung injury
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  48. Jan 2025
  49. www.nature.com www.nature.com
    Generating allogeneic CAR-NKT cells for off-the-shelf cancer immunotherapy with genetically engineered HSP cells and feeder-free differentiation culture
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    FOXR2 Targets LHX6+/DLX+ Neural Lineages to Drive Central Nervous System Neuroblastoma
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    Neonatal Brain Injury Triggers Niche-Specific Changes to Cellular Biogeography
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    KDM6B-dependent epigenetic programming of uterine fibroblasts in early pregnancy regulates parturition timing in mice
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    CRISPRi-based screens in iAssembloids to elucidate neuron-glia interactions
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    Single cell approaches define neural stem cell niches and identify microglial ligands that can enhance precursor-mediated oligodendrogenesis
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    Sex-dependent molecular landscape of Alzheimer's disease revealed by large-scale single-cell transcriptomics
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    Nuclear respiratory factor-1 (NRF1) induction as a powerful strategy to deter mitochondrial dysfunction and senescence in mesenchymal stem cells
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    Splenic fibroblasts control marginal zone B cell movement and function via two distinct Notch2-dependent regulatory programs
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  59. Dec 2024
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    Mechanism of enhancing chemotherapy efficacy in pancreatic ductal adenocarcinoma with paricalcitol and hydroxychloroquine
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    Expanding GABAergic Neuronal Diversity in iPSC-Derived Disease Models
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    Cell therapy with human IL-10-producing ILC2s limits xenogeneic graft-versus-host disease by inhibiting pathogenic T cell responses
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    Long non-coding RNA Malat1 fine-tunes bone homeostasis and repair by orchestrating cellular crosstalk and β-catenin-OPG/Jagged1 pathway
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    Decoding Functional and Developmental Trajectories of Tissue-Resident Uterine Dendritic Cells Through Integrative Omics
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    CD69+CD103+CD8+ tissue-resident memory T cells possess stronger anti-tumor activity and predict better prognosis in colorectal cancer
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    Single-cell transcriptomics of vomeronasal neuroepithelium reveals a differential endoplasmic reticulum environment amongst neuronal subtypes
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    B7-H3–Targeted CAR-Vδ1T Cells Exhibit Potent Broad-Spectrum Activity against Solid Tumors
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    Single-Cell Analysis of Bone Marrow CD8+ T Cells in Myeloid Neoplasms Reveals Pathways Associated with Disease Progression and Response to Treatment with Azacitidine
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    Microglial lipid phosphatase SHIP1 limits complement-mediated synaptic pruning in the healthy developing hippocampus
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    Combined inhibition of S100A4 and TIGIT suppresses late-stage breast cancer metastasis to the lung by activating T and NK cells
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    Cycling alpha cells in regenerative drug-treated human pancreatic islets may serve as key beta cell progenitors
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    Biased signaling by mutant EGFR underlies dependence on PKCα in lung adenocarcinoma
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    Flt3L enhances clonal diversification and selective expansion of intratumoral CD8+ T cells while differentiating into effector-like cells
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  76. Nov 2024
  77. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Modeling early phenotypes of Parkinson’s disease by age-induced midbrain-striatum assembloids
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    The Drosophila adult midgut progenitor cells arise from asymmetric divisions of neuroblast-like cells
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    The immune landscape of murine skeletal muscle regeneration and aging
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    Glioblastoma functional heterogeneity and enrichment of cancer stem cells with tumor recurrence
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    Control of Murine Brown Adipocyte Development by GATA6
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    Type III interferons induce pyroptosis in gut epithelial cells and impair mucosal repair
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  83. www.mdpi.com www.mdpi.com
    NF-ΚB Activation as a Key Driver in Chronic Lymphocytic Leukemia Evolution to Richter’s Syndrome: Unraveling the Influence of Immune Microenvironment Dynamics
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  84. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Age-Associated Contraction of Tumor-Specific T Cells Impairs Antitumor Immunity
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    Astrocyte allocation during brain development is controlled by Tcf4-mediated fate restriction
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  88. Oct 2024
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Biomarker analyses investigating disease biology and associations with outcomes in the JAVELIN Merkel 200 trial of avelumab in metastatic Merkel cell carcinoma
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    H3.3 G34W Promotes Growth and Impedes Differentiation of Osteoblast-Like Mesenchymal Progenitors in Giant Cell Tumor of Bone
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    aacrjournals.org/cancerdiscovery/article/10/12/1968/2414/H3-3-G34W-Promotes-Growth-and-Impedes
  91. Sep 2024
  92. elifesciences.org elifesciences.org
    Muscle-resident mesenchymal progenitors sense and repair peripheral nerve injury via the GDNF-BDNF axis
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    Single-cell and bulk transcriptional profiling of mouse ovaries reveals novel genes and pathways associated with DNA damage response in oocytes
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    A PD-1-targeted, receptor-masked IL-2 immunocytokine that engages IL-2Rα strengthens T cell-mediated anti-tumor therapies
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    Exploring the role of KIR3DL2 on NK cells in hepatocellular carcinoma and its potential prognostic implications
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    Reconstitution of the Multiple Myeloma Microenvironment Following Lymphodepletion with BCMA CAR-T Therapy
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  197. Nov 2023
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