6,993 Matching Annotations
  1. Jun 2022
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    Glycerate from intestinal fructose metabolism induces islet cell damage and glucose intolerance
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    Identification of metabolic pathways underlying FGF1 and CHIR99021-mediated cardioprotection
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    sciencedirect.com/science/article/pii/S2589004222007180
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    Lockd promotes myoblast proliferation and muscle regeneration via binding with DHX36 to facilitate 5′ UTR rG4 unwinding and Anp32e translation
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    sciencedirect.com/science/article/pii/S2211124722007094
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    Neural circuit pathology driven by Shank3 mutation disrupts social behaviors
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    Translocator Protein Ligand Etifoxine Attenuates MPTP-Induced Neurotoxicity
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    frontiersin.org/article/10.3389/fnmol.2022.850904/full
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    Optical analysis of AMPAR-mediated synaptic scaling in mouse hippocampus
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    Succinate metabolism in the retinal pigment epithelium uncouples respiration from ATP synthesis
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    Itaconate is a lysosomal inducer that promotes antibacterial innate immunity
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    Evaluating the glycolytic potential of mouse costimulated effector CD8+ T cells ex vivo
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    Inhibition of ATP-citrate lyase improves NASH, liver fibrosis, and dyslipidemia
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    Phosphoproteomic of the acetylcholine pathway enables discovery of the PKC-β-PIX-Rac1-PAK cascade as a stimulatory signal for aversive learning
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    Differentiation of Hebbian and homeostatic plasticity mechanisms within layer 5 visual cortex neurons
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    BCL6-dependent TCF-1+ progenitor cells maintain effector and helper CD4+ T cell responses to persistent antigen
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    Exercise-induced engagement of the IL-15/IL-15Rα axis promotes anti-tumor immunity in pancreatic cancer
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    An inter-organ neural circuit for appetite suppression
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    Cross-tissue, single-cell stromal atlas identifies shared pathological fibroblast phenotypes in four chronic inflammatory diseases
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    Fatty acid oxidation protects cancer cells from apoptosis by increasing mitochondrial membrane lipids
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    Gut bacterial isoamylamine promotes age-related cognitive dysfunction by promoting microglial cell death
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    Neuronal NLRP3 is a parkin substrate that drives neurodegeneration in Parkinson’s disease
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    A pro-metastatic tRNA fragment drives Nucleolin oligomerization and stabilization of its bound metabolic mRNAs
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    Carbon monoxide activates PERK-regulated autophagy to induce immunometabolic reprogramming and boost anti-tumor T cell function
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    A tonic nicotinic brake controls spike timing in striatal spiny projection neurons
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    mGlu1-mediated restoration of prefrontal cortex inhibitory signaling reverses social and cognitive deficits in an NMDA hypofunction model in mice
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  25. May 2022
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    Rho–Rho-Kinase Regulates Ras-ERK Signaling Through SynGAP1 for Dendritic Spine Morphology
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    Binary outcomes of enhancer activity underlie stable random monoallelic expression
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    A versatile viral toolkit for functional discovery in the nervous system
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    GABAergic interneurons expressing the α2 nicotinic receptor subunit are functionally integrated in the striatal microcircuit
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    Alcohol induced increases in sperm Histone H3 lysine 4 trimethylation correlate with increased placental CTCF occupancy and altered developmental programming
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    DDX41 is required for cGAS-STING activation against DNA virus infection
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    Corneal tissue-resident memory T cells form a unique immune compartment at the ocular surface
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    Stimulation of medial amygdala GABA neurons with kinetically different channelrhodopsins yields opposite behavioral outcomes
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    Fine mapping and candidate gene analysis of a dravet syndrome modifier locus on mouse chromosome 11
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    IgM-associated gut bacteria in obesity and type 2 diabetes in C57BL/6 mice and humans
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    Altered synaptic plasticity of the longitudinal dentate gyrus network in noise-induced anxiety
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    Single-cell suspension preparation from murine organs following in vivo mRNA-LNP exposure
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    Co-registration of mouse cortical structures between in vivo and ex vivo images using tangential sectioning
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    A highland-adaptation mutation of the Epas1 protein increases its stability and disrupts the circadian clock in the plateau pika
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    Secretion of interleukin-1 by dedifferentiated melanoma cells inhibits JAK1-STAT3-driven actomyosin contractility of lymph node fibroblastic reticular cells
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    The non-essential TSC complex component TBC1D7 restricts tissue mTORC1 signaling and brain and neuron growth
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    Activation of the transcription factor NRF2 mediates the anti-inflammatory properties of a subset of over-the-counter and prescription NSAIDs
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    Choice-selective sequences dominate in cortical relative to thalamic inputs to NAc to support reinforcement learning
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    Fasting induces a highly resilient deep quiescent state in muscle stem cells via ketone body signaling
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    An integrated transcriptomic and epigenomic atlas of mouse primary motor cortex cell types
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    Defective fractalkine-CX3CR1 signaling aggravates neuroinflammation and affects recovery from cuprizone-induced demyelination
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    Mycobacterium tuberculosis impedes CD40-dependent notch signaling to restrict Th17 polarization during infection
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    Disrupting autorepression circuitry generates “open-loop lethality” to yield escape-resistant antiviral agents
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    JAM-A Signals Through the Hippo Pathway to Regulate Intestinal Epithelial Proliferation
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    Tumor ENPP1(CD203a)/Haptoglobin Axis Exploits Myeloid-Derived Suppressor Cells to Promote Post-Radiotherapy Local Recurrence in Breast Cancer
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    Tumor Microenvironment Acidity Triggers Lipid Accumulation in Liver Cancer via SCD1 Activation
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    HIV Tat and cocaine interactively alter genome-wide DNA methylation and gene expression and exacerbate learning and memory impairments
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    Analysis of the interplay between hepatitis B virus-positive hepatocytes and Kupffer cells ex vivo using mice as a model
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    Lymph node colonization induces tumor-immune tolerance to promote distant metastasis
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    A TLR4-independent critical role for CD14 in intracellular LPS sensing
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    Movement-specific signaling is differentially distributed across motor cortex layer 5 projection neuron classes
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    Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development
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    Aryl hydrocarbon receptor signals in epithelial cells govern the recruitment and location of Helios+ Tregs in the gut
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    Circadian activities of the brain MNK-eIF4E signaling axis contribute to diurnal rhythms of some cognitive functions
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    Fluoxetine exposure throughout neurodevelopment differentially influences basilar dendritic morphology in the motor and prefrontal cortices
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    Mesothelial cell-derived antigen-presenting cancer-associated fibroblasts induce expansion of regulatory T cells in pancreatic cancer
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    Nasally-delivered interferon-λ protects mice against infection by SARS-CoV-2 variants including Omicron
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    Antigen presentation safeguards the integrity of the hematopoietic stem cell pool
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    p57Kip2 imposes the reserve stem cell state of gastric chief cells
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    Ripple-selective GABAergic projection cells in the hippocampus
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    Intracellular infection and immune system cues rewire adipocytes to acquire immune function
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    Activation of a Locus Coeruleus to Dorsal Hippocampus Noradrenergic Circuit Facilitates Associative Learning
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    FILIP1L loss is a driver of aggressive mucinous colorectal adenocarcinoma and mediates cytokinesis defects through PFDN1
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    Colony stimulating factor-1 producing endothelial cells and mesenchymal stromal cells maintain monocytes within a perivascular bone marrow niche
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    Oleic acid is an endogenous ligand of TLX/NR2E1 that triggers hippocampal neurogenesis
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    Differences in spike generation instead of synaptic inputs determine the feature selectivity of two retinal cell types
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    Cocaine Modulates the Neuronal Endosomal System and Extracellular Vesicles in a Sex-Dependent Manner
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    link.springer.com/article/10.1007/s11064-022-03612-1
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    Acute axon damage and demyelination are mitigated by 4-aminopyridine (4-AP) therapy after experimental traumatic brain injury
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    link.springer.com/article/10.1186/s40478-022-01366-z
  82. Apr 2022
  83. www.science.org www.science.org
    A common framework of monocyte-derived macrophage activation
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    science.org/doi/10.1126/sciimmunol.abl7482
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    Functional genetic screen identifies ITPR3/calcium/RELB axis as a driver of colorectal cancer metastatic liver colonization
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    Multimodal imaging of synaptic vesicles with a single probe
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    Tissue remodeling by an opportunistic pathogen triggers allergic inflammation
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    Maladaptive innate immune training of myelopoiesis links inflammatory comorbidities
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    In situ identification of cellular drug targets in mammalian tissue
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    Type VI secretion systems of pathogenic and commensal bacteria mediate niche occupancy in the gut
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    Tankyrase Inhibitor OM-153 Demonstrates Antitumor Efficacy and a Therapeutic Window in Mouse Models
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    aacrjournals.org/cancerrescommun/article/2/4/233/694510/The-Tankyrase-Inhibitor-OM-153-Demonstrates
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    Beta-Amyloid (Aβ1-42) Increases the Expression of NKCC1 in the Mouse Hippocampus
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