8,341 Matching Annotations
  1. Nov 2022
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    Prenatal inflammation perturbs murine fetal hematopoietic development and causes persistent changes to postnatal immunity
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    sciencedirect.com/science/article/pii/S2211124722015510
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    Exercise increases information content and affects long-term stability of hippocampal place codes
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    sciencedirect.com/science/article/pii/S2211124722015698
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    Learning-related contraction of gray matter in rodent sensorimotor cortex is associated with adaptive myelination
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    ncbi.nlm.nih.gov/pmc/articles/PMC9678357/
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    Systemic administration of novel engineered AAV capsids facilitates enhanced transgene expression in the macaque CNS
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    sciencedirect.com/science/article/pii/S2666634022004561
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    Systematic single-cell pathway analysis to characterize early T cell activation
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    sciencedirect.com/science/article/pii/S2211124722015716
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    Ionic and morphological contributions to the variable gain of membrane responses in layer 2/3 pyramidal neurons of mouse primary visual cortex
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    journals.physiology.org/doi/10.1152/jn.00181.2022
  8. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Continued P2X7 Activation Leads to Mitochondrial Fission and Compromising Microglial Phagocytosis after Subarachnoid Haemorrhage
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15712
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    Heat shock factor HSF1 regulates BDNF gene promoters upon acute stress in the hippocampus, together with pCREB
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15707
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    A DARPin-based molecular toolset to probe gephyrin and inhibitory synapse biology
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    ncbi.nlm.nih.gov/pmc/articles/PMC9674349/
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    Microtubule retrograde flow retains neuronal polarization in a fluctuating state
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    ncbi.nlm.nih.gov/pmc/articles/PMC9635824/
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    LRG1 is an adipokine that promotes insulin sensitivity and suppresses inflammation
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    Pericyte Mapping in Cerebral Slices with the Far-red Fluorophore TO-PRO-3
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    Effect of inactivation of Mst1 and Mst2 in the mouse adrenal cortex
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    academic.oup.com/jes/article/7/1/bvac143/6702160
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    Tributyltin Protects Against Ovariectomy-Induced Trabecular Bone Loss in C57BL/6J Mice with an Attenuated Effect in High Fat Fed Mice
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    Transplanted human induced pluripotent stem cells- derived retinal ganglion cells embed within mouse retinas and are electrophysiologically functional
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    ncbi.nlm.nih.gov/pmc/articles/PMC9646916/
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    Topographical organization and morphology of substance P (SP)-immunoreactive axons in the whole stomach of mice
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    onlinelibrary.wiley.com/doi/10.1002/cne.25386
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    Reciprocal effects of mTOR inhibitors on pro-survival proteins dictate therapeutic responses in tuberous sclerosis complex
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    Agr2-associated ER stress promotes adherent-invasive E. coli dysbiosis and triggers CD103+ dendritic cell IL-23-dependent ileocolitis
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    Monocytes maintain central nervous system homeostasis following helminth-induced inflammation
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    BlpC-mediated selfish program leads to rapid loss of Streptococcus pneumoniae clonal diversity during infection
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    Dually innervated dendritic spines develop in the absence of excitatory activity and resist plasticity through tonic inhibitory crosstalk
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    A dietary change to a high-fat diet initiates a rapid adaptation of the intestine
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    Estrone, the major postmenopausal estrogen, binds ERa to induce SNAI2, epithelial-to-mesenchymal transition, and ER+ breast cancer metastasis
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    The transcription factor IRF2 drives interferon-mediated CD8+ T cell exhaustion to restrict anti-tumor immunity
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    The adhesion G-protein-coupled receptor Gpr116 is essential to maintain the skeletal muscle stem cell pool
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    Trigeminal afferents sense locomotion-related meningeal deformations
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    Gestationally dependent immune organization at the maternal-fetal interface
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    Development of single-molecule ubiquitination mediated fluorescence complementation to visualize protein ubiquitination dynamics in dendrites
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    Assessment of spatial transcriptomics for oncology discovery
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    The miR-124-AMPAR pathway connects polygenic risks with behavioral changes shared between schizophrenia and bipolar disorder
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    Extensive preclinical validation of combined RMC-4550 and LY3214996 supports clinical investigation for KRAS mutant pancreatic cancer
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    Genome-scale CRISPR screening in a single mouse liver
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    Protocol to isolate mature thymic T cell subsets using fluorescence-activated cell sorting for assessing gene expression by RNA-seq and transcription factor binding across the genome by CUT&RUN
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    R1441C and G2019S LRRK2 knockin mice have distinct striatal molecular, physiological, and behavioral alterations
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    Architecture of the outbred brown fat proteome defines regulators of metabolic physiology
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    Protein Expression of Amino Acid Transporters Is Altered in Isolated Cerebral Microvessels of 5xFAD Mouse Model of Alzheimer’s Disease
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    SLC38A2 provides proline and alanine to regulate postnatal bone mass accrual in mice
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    Ketone Body Augmentation Decreases Methacholine Hyperresponsiveness in Mouse Models of Allergic Asthma
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    CyclinD2-mediated regulation of neurogenic output from the retinal ciliary margin is perturbed in albinism
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    Tuft-cell-intrinsic and -extrinsic mediators of norovirus tropism regulate viral immunity
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    Loss of neuronal Tet2 enhances hippocampal-dependent cognitive function
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    Extracellular vesicles from pristane-treated CD38-deficient mice express an anti-inflammatory neutrophil protein signature, which reflects the mild lupus severity elicited in these mice
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    Sonic hedgehog-dependent recruitment of GABAergic interneurons into the developing visual thalamus
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    An ancestral mycobacterial effector promotes dissemination of infection
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    Lipopolysaccharide induces placental mitochondrial dysfunction in murine and human systems by reducing MNRR1 levels via a TLR4-independent pathway
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    Phosphorylation of RXRα mediates the effect of JNK to suppress hepatic FGF21 expression and promote metabolic syndrome
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    Mesoscale connections and gene expression empower whole-brain modeling of α-synuclein spread, aggregation, and decay dynamics
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    Dual anti-angiogenic and anti-metastatic activity of myriocin synergistically enhances the anti-tumor activity of cisplatin
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    Engineered human cytokine/antibody fusion proteins expand regulatory T cells and confer autoimmune disease protection
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    Tumor-intrinsic SIRPA promotes sensitivity to checkpoint inhibition immunotherapy in melanoma
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    A binocular perception deficit characterizes prey pursuit in developing mice
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    Deep tissue infection by an invasive human fungal pathogen requires lipid-based suppression of the IL-17 response
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    Gut colonization by Proteobacteria alters host metabolism and modulates cocaine neurobehavioral responses
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    Prolactin Action Is Necessary for Parental Behavior in Male Mice
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    CD74 as a regulator of transcription in normal B cells
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    Melanocortin-4 receptors activate sympathetic preganglionic neurons and elevate blood pressure via TRPV1
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    Mobilizing phospholipids on tumor plasma membrane implicates phosphatidylserine externalization blockade for cancer immunotherapy
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    Long-term progression of retinal degeneration in a preclinical model of CLN7 Batten disease as a baseline for testing clinical therapeutics
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    Integration of mouse ovary morphogenesis with developmental dynamics of the oviduct, ovarian ligaments, and rete ovarii
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  63. Oct 2022
  64. elifesciences.org elifesciences.org
    BehaviorDEPOT is a simple, flexible tool for automated behavioral detection based on markerless pose tracking
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    CRISPRi screens in human iPSC-derived astrocytes elucidate regulators of distinct inflammatory reactive states
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    High-throughput sequencing of single neuron projections reveals spatial organization in the olfactory cortex
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    K+ channel Kv4.1 is expressed in the nociceptors/secondary nociceptive neurons and participates in pain regulation
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    GPCR-Mediated Regulation of Fuel and Energy Metabolism in Peripheral Tissues: Glucagon receptor signaling at white adipose tissue does not regulate lipolysis
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    Notch signaling promotes mature T-cell lymphomagenesis
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    aacrjournals.org/cancerres/article/82/20/3763/709632/Notch-Signaling-Promotes-Mature-T-Cell
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    Phosphoproteomic mapping reveals distinct signaling actions and activation of muscle protein synthesis by Isthmin-1
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    Increased KIF11/Kinesin-5 expression offsets Alzheimer Aβ-mediated toxicity and cognitive dysfunction
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    Systemic vaccination induces CD8+ T cells and remodels the tumor microenvironment
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    Dopaminergic neurons are not a major SHH ligand source for striatal cholinergic or PV interneurons
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    Gasdermin D restricts anti-tumor immunity during PD-L1 checkpoint blockade
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    A protocol to visualize on-target specific drug binding in mammalian tissue with cellular resolution using tissue clearing and click chemistry
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    Genome-scale CRISPR screening reveals that C3aR signaling is critical for rapid capture of fungi by macrophages
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    Genome-wide CRISPR screen reveals v-ATPase as a drug target to lower levels of ALS protein ataxin-2
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    The transcription factor Bach2 negatively regulates murine natural killer cell maturation and function
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    A multienzyme S-nitrosylation cascade regulates cholesterol homeostasis
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    Favine/CCDC3 deficiency accelerated atherosclerosis and thrombus formation is associated with decreased MEF2C-KLF2 pathway
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    REM sleep-active hypothalamic neurons may contribute to hippocampal social-memory consolidation
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    Defibrinogenation Ameliorates Retinal Microgliosis and Inflammation in A CX3CR1-Independent Manner
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    Comprehensive single-cell transcriptional profiling defines shared and unique epithelial injury responses during kidney fibrosis
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    Mapping brain gene coexpression in daytime transcriptomes unveils diurnal molecular networks and deciphers perturbation gene signatures
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    Gut-innervating nociceptors regulate the intestinal microbiota to promote tissue protection
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    Different priming states of synaptic vesicles underlie distinct release probabilities at hippocampal excitatory synapses
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    Nociceptor neurons direct goblet cells via a CGRP-RAMP1 axis to drive mucus production and gut barrier protection
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    Transcription factor RORα enforces stability of the Th17 cell effector program by binding to a Rorc cis-regulatory element
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    Manipulation-specific cortical activity as mice handle food
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    Cellular barcoding of protozoan pathogens reveals the within-host population dynamics of Toxoplasma gondii host colonization
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    Convergent cerebrospinal fluid proteomes and metabolic ontologies in humans and animal models of Rett syndrome
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  184. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tonic activity in lateral habenula neurons acts as a neutral valence brake on reward-seeking behavior
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  185. Aug 2022
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    Integrated single-cell transcriptomic analyses reveal that GPNMB-high macrophages promote PN-MES transition and impede T cell activation in GBM
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    sciencedirect.com/science/article/pii/S2352396422004212
  187. www.sciencedirect.com www.sciencedirect.com
    RBM45 is an m6A-binding protein that affects neuronal differentiation and the splicing of a subset of mRNAs
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    sciencedirect.com/science/article/pii/S2211124722011135
  188. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    B Cells Produce the Tissue-Protective Protein RELMα during Helminth Infection, which Inhibits IL-17 Expression and Limits Emphysema
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    ncbi.nlm.nih.gov/pmc/articles/PMC9413029/
  189. www.sciencedirect.com www.sciencedirect.com
    Induction of tumor cell autosis by myxoma virus-infected CAR-T and TCR-T cells to overcome primary and acquired resistance
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  190. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Toxic and Phenotypic Effects of AAV_Cre Used to Transduce Mesencephalic Dopaminergic Neurons
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    Divergent roles for the gut intraepithelial lymphocyte GLP-1R in control of metabolism, microbiota, and T cell-induced inflammation
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    sciencedirect.com/science/article/pii/S1550413122003461
  192. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Paternal alcohol exposures program intergenerational hormetic effects on offspring fetoplacental growth
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    Protocol to assess the tolerogenic properties of adoptively transferred dendritic cells during murine experimental autoimmune encephalomyelitis
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    Co-expression network analysis of human tau-transgenic mice reveals protein modules associated with tau-induced pathologies
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  195. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sensitivity to extracellular potassium underlies type-intrinsic differences in retinal ganglion cell excitability
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    Antibodies from primary humoral responses modulate recruitment of naive B cells during secondary responses
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    Fungal ablation and transplantation of specific fungal species into PDAC tumor-bearing mice
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