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463 Matching Annotations

Sep 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Inhibition of the polyamine synthesis enzyme ornithine decarboxylase sensitizes triple-negative breast cancer cells to cytotoxic chemotherapy

1
1. scibot 04 Sep 2020
  
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  pH2A.XS139
  
  DOI: 10.1074/jbc.RA119.012376
  
  Resource: (Cell Signaling Technology Cat# 9718, RRID:AB_2118009)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2118009
  
  Curator comments: Phospho-Histone H2A.X (Ser139) (20E3) Rabbit mAb antibody Cell Signaling Technology Cat# 9718
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7212655/
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

1
1. scibot 03 Sep 2020
  
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  anti‐rabbit γ‐H2AX
  
  DOI: 10.1111/bph.15149
  
  Resource: (Cell Signaling Technology Cat# 9718, RRID:AB_2118009)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2118009
  
  Curator comments: Phospho-Histone H2A.X (Ser139) (20E3) Rabbit mAb antibody Cell Signaling Technology Cat# 9718
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15149
Jan 2020
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p63 and SOX2 Dictate Glucose Reliance and Metabolic Vulnerabilities in Squamous Cell Carcinomas

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2118009
  
  DOI: 10.1016/j.celrep.2019.07.027
  
  Resource: (Cell Signaling Technology Cat# 9718, RRID:AB_2118009)
  
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sciencedirect.com/science/article/pii/S2211124719309246
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Stress-Induced Changes in Bone Marrow Stromal Cell Populations Revealed through Single-Cell Protein Expression Mapping

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2118009
  
  DOI: 10.1016/j.stem.2019.06.003
  
  Resource: (Cell Signaling Technology Cat# 9718, RRID:AB_2118009)
  
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sciencedirect.com/science/article/pii/S193459091930267X
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Poly(ADP-Ribose) Links the DNA Damage Response and Biomineralization

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2118009
  
  DOI: 10.1016/j.celrep.2019.05.038
  
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sciencedirect.com/science/article/pii/S2211124719306588
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Amelioration of age‐related brain function decline by Bruton's tyrosine kinase inhibition

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2118009
  
  DOI: 10.1111/acel.13079
  
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onlinelibrary.wiley.com/doi/10.1111/acel.13079
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Development and Characterization of a Wee1 Kinase Degrader

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2118009
  
  DOI: 10.1016/j.chembiol.2019.10.013
  
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sciencedirect.com/science/article/pii/S2451945619303587
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CDK7 Inhibition Potentiates Genome Instability Triggering Anti-tumor Immunity in Small Cell Lung Cancer

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2118009
  
  DOI: 10.1016/j.ccell.2019.11.003
  
  Resource: (Cell Signaling Technology Cat# 9718, RRID:AB_2118009)
  
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  RRID:AB_2118009 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610819305239
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Loss of Slug Compromises DNA Damage Repair and Accelerates Stem Cell Aging in Mammary Epithelium

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2118009
  
  DOI: 10.1016/j.celrep.2019.06.043
  
  Resource: (Cell Signaling Technology Cat# 9718, RRID:AB_2118009)
  
  Curator: @ethanbadger
  
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  RRID:AB_2118009 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124719308162
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Therapeutic Targeting of RNA Splicing Catalysis through Inhibition of Protein Arginine Methylation

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2118009
  
  DOI: 10.1016/j.ccell.2019.07.003
  
  Resource: (Cell Signaling Technology Cat# 9718, RRID:AB_2118009)
  
  Curator: @ethanbadger
  
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  RRID:AB_2118009 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610819303307
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A Yap-Myc-Sox2-p53 Regulatory Network Dictates Metabolic Homeostasis and Differentiation in Kras-Driven Pancreatic Ductal Adenocarcinomas

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2118009
  
  DOI: 10.1016/j.devcel.2019.07.022
  
  Resource: (Cell Signaling Technology Cat# 9718, RRID:AB_2118009)
  
  Curator: @ethanbadger
  
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  RRID:AB_2118009 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1534580719306288
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Torin2 Exploits Replication and Checkpoint Vulnerabilities to Cause Death of PI3K-Activated Triple-Negative Breast Cancer Cells

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2118009
  
  DOI: 10.1016/j.cels.2019.11.001
  
  Resource: (Cell Signaling Technology Cat# 9718, RRID:AB_2118009)
  
  Curator: @ethanbadger
  
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  RRID:AB_2118009 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2405471219303874
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Small Molecule Inhibitors of KDM5 Histone Demethylases Increase the Radiosensitivity of Breast Cancer Cells Overexpressing JARID1B

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2118009
  
  DOI: 10.3390/molecules24091739
  
  Resource: (Cell Signaling Technology Cat# 9718, RRID:AB_2118009)
  
  Curator: @evieth
  
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  RRID:AB_2118009 RRIDCUR:Validated
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ncbi.nlm.nih.gov/pmc/articles/PMC6540222/
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Modeling of Cisplatin-Induced Signaling Dynamics in Triple-Negative Breast Cancer Cells Reveals Mediators of Sensitivity

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2118009
  
  DOI: 10.1016/j.celrep.2019.07.070
  
  Resource: (Cell Signaling Technology Cat# 9718, RRID:AB_2118009)
  
  Curator: @ethanbadger
  
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  RRID:AB_2118009 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S221112471930974X
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Altered m6A Modification of Specific Cellular Transcripts Affects Flaviviridae Infection

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2118009
  
  DOI: 10.1016/j.molcel.2019.11.007
  
  Resource: (Cell Signaling Technology Cat# 9718, RRID:AB_2118009)
  
  Curator: @ethanbadger
  
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  RRID:AB_2118009 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1097276519308366
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Small-Molecule MYC Inhibitors Suppress Tumor Growth and Enhance Immunotherapy

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2118009
  
  DOI: 10.1016/j.ccell.2019.10.001
  
  Resource: (Cell Signaling Technology Cat# 9718, RRID:AB_2118009)
  
  Curator: @ethanbadger
  
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  RRID:AB_2118009 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610819304398
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Patterns of Early p21 Dynamics Determine Proliferation-Senescence Cell Fate after Chemotherapy

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2118009
  
  DOI: 10.1016/j.cell.2019.05.041
  
  Resource: (Cell Signaling Technology Cat# 9718, RRID:AB_2118009)
  
  Curator: @ethanbadger
  
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  RRID:AB_2118009 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S0092867419306129
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Therapeutic Targeting of CDK12/CDK13 in Triple-Negative Breast Cancer

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2118009
  
  DOI: 10.1016/j.ccell.2019.09.004
  
  Resource: (Cell Signaling Technology Cat# 9718, RRID:AB_2118009)
  
  Curator: @ethanbadger
  
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  RRID:AB_2118009 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610819304246
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Cerebral dopamine Neurotrophic factor–deficiency leads to degeneration of enteric neurons and altered brain dopamine neuronal function in mice

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2118009
  
  DOI: 10.1016/j.nbd.2019.104696
  
  Resource: (Cell Signaling Technology Cat# 9718, RRID:AB_2118009)
  
  Curator: @ethanbadger
  
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  RRID:AB_2118009 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S0969996119303717
link.springer.com link.springer.com

Fibroblasts from patients with idiopathic pulmonary fibrosis are resistant to cisplatin-induced cell death via enhanced CK2-dependent XRCC1 activity

1
1. scibot 13 Jan 2020
  
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  AB_2118009
  
  DOI: 10.1007/s10495-019-01529-9
  
  Resource: (Cell Signaling Technology Cat# 9718, RRID:AB_2118009)
  
  Curator: @Naa003
  
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  RRID:AB_2118009 RRIDCUR:Validated
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link.springer.com/article/10.1007/s10495-019-01529-9
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High Glucose Triggers Nucleotide Imbalance through O-GlcNAcylation of Key Enzymes and Induces KRAS Mutation in Pancreatic Cells

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2118009
  
  DOI: 10.1016/j.cmet.2019.02.005
  
  Resource: (Cell Signaling Technology Cat# 9718, RRID:AB_2118009)
  
  Curator: @ethanbadger
  
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  RRID:AB_2118009 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1550413119300695
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DNA Damage Signaling-Induced Cancer Cell Reprogramming as a Driver of Tumor Relapse

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2118009
  
  DOI: 10.1016/j.molcel.2019.03.002
  
  Resource: (Cell Signaling Technology Cat# 9718, RRID:AB_2118009)
  
  Curator: @ethanbadger
  
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  RRID:AB_2118009 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1097276519301765
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Untitled document

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2118009
  
  DOI: 10.1016/j.devcel.2019.04.014
  
  Resource: (Cell Signaling Technology Cat# 9718, RRID:AB_2118009)
  
  Curator: @ethanbadger
  
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  RRID:AB_2118009 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1534580719302849
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Untitled document

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1. scibot 13 Jan 2020
  
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  RRID:AB_2118009
  
  DOI: 10.1016/j.cmet.2018.12.020
  
  Resource: (Cell Signaling Technology Cat# 9718, RRID:AB_2118009)
  
  Curator: @ethanbadger
  
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  RRID:AB_2118009 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1550413118307575
onlinelibrary.wiley.com onlinelibrary.wiley.com

JARID1B expression and its function in DNA damage repair are tightly regulated by miRNAs in breast cancer

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2118009
  
  DOI: 10.1111/cas.13925
  
  Resource: (Cell Signaling Technology Cat# 9718, RRID:AB_2118009)
  
  Curator: @Naa003
  
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  RRID:AB_2118009 RRIDCUR:Validated
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onlinelibrary.wiley.com/doi/full/10.1111/cas.13925
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Obesity-Induced Cellular Senescence Drives Anxiety and Impairs Neurogenesis

1
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  RRID:AB_2118009
  
  DOI: 10.1016/j.cmet.2018.12.008
  
  Resource: (Cell Signaling Technology Cat# 9718, RRID:AB_2118009)
  
  Curator: @evieth
  
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  RRID:AB_2118009 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1550413118307459
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Untitled document

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  RRID:AB_2118009
  
  DOI: 10.1016/j.celrep.2018.12.089
  
  Resource: (Cell Signaling Technology Cat# 9718, RRID:AB_2118009)
  
  Curator: @ethanbadger
  
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  RRID:AB_2118009 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124718320497
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Untitled document

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  RRID:AB_2118009
  
  DOI: 10.1016/j.cmet.2019.02.001
  
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sciencedirect.com/science/article/pii/S1550413119300658
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Untitled document

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  RRID:AB_2118009
  
  DOI: 10.1016/j.ccell.2018.12.013
  
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sciencedirect.com/science/article/pii/S1535610818305853
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TOP2β-Dependent Nuclear DNA Damage Shapes Extracellular Growth Factor Responses via Dynamic AKT Phosphorylation to Control Virus Latency

1
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  RRID:AB_2118009
  
  DOI: 10.1016/j.molcel.2019.02.032
  
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  RRID:AB_2118009 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1097276519301431
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Untitled document

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  RRID:AB_2118009
  
  DOI: 10.1016/j.ebiom.2019.04.060
  
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sciencedirect.com/science/article/pii/S2352396419302993
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

FXR Regulates Intestinal Cancer Stem Cell Proliferation

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1. scibot 13 Jan 2020
  
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  RRID:AB_2118009
  
  DOI: 10.1016/j.cell.2019.01.036
  
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  Curator: @ethanbadger
  
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  RRID:AB_2118009 RRIDCUR:Validated
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pmc.ncbi.nlm.nih.gov/articles/PMC6701863/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

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  RRID:AB_2118009
  
  DOI: 10.7554/eLife.41351
  
  Resource: (Cell Signaling Technology Cat# 9718, RRID:AB_2118009)
  
  Curator: @evieth
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6351101/
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Untitled document

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1. scibot 12 Jan 2020
  
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  RRID:AB_2118009
  
  DOI: 10.1016/j.cmet.2019.03.001
  
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Pregnancy in human <Emphasis Type="Italic">IAPP</Emphasis> transgenic mice recapitulates beta cell stress in type 2 diabetes

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The Cdkn1aSUPER Mouse as a Tool to Study p53-Mediated Tumor Suppression

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Impaired Notch Signaling Leads to a Decrease in p53 Activity and Mitotic Catastrophe in Aged Muscle Stem Cells

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Multi-level Proteomics Identifies CT45 as a Chemosensitivity Mediator and Immunotherapy Target in Ovarian Cancer

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Histone Ubiquitination by the DNA Damage Response Is Required for Efficient DNA Replication in Unperturbed S Phase

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Therapeutic Ablation of Gain-of-Function Mutant p53 in Colorectal Cancer Inhibits Stat3-Mediated Tumor Growth and Invasion

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Id1 Ablation Protects Hematopoietic Stem Cells from Stress-Induced Exhaustion and Aging

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MAST1 Drives Cisplatin Resistance in Human Cancers by Rewiring cRaf-Independent MEK Activation

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Liver Cancer Initiation Requires p53 Inhibition by CD44-Enhanced Growth Factor Signaling

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Detection of DNA Double Strand Breaks by γH2AX Does Not Result in 53bp1 Recruitment in Mouse Retinal Tissues

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SOD1 Phosphorylation by mTORC1 Couples Nutrient Sensing and Redox Regulation

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A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD+ Decline

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PAF-Myc-Controlled Cell Stemness Is Required for Intestinal Regeneration and Tumorigenesis

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An Integrated Genome-wide CRISPRa Approach to Functionalize lncRNAs in Drug Resistance

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Myeloid Cell-Derived Reactive Oxygen Species Induce Epithelial Mutagenesis

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Melanocyte Stem Cell Activation and Translocation Initiate Cutaneous Melanoma in Response to UV Exposure

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MST4 Phosphorylation of ATG4B Regulates Autophagic Activity, Tumorigenicity, and Radioresistance in Glioblastoma

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A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development

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Transcription-Replication Conflict Orientation Modulates R-Loop Levels and Activates Distinct DNA Damage Responses

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A Sacrifice-for-Survival Mechanism Protects Root Stem Cell Niche from Chilling Stress

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Chromosome Mis-segregation Generates Cell-Cycle-Arrested Cells with Complex Karyotypes that Are Eliminated by the Immune System

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DNA-PK Promotes the Mitochondrial, Metabolic, and Physical Decline that Occurs During Aging

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BTBD18 Regulates a Subset of piRNA-Generating Loci through Transcription Elongation in Mice

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Functions of Replication Protein A as a Sensor of R Loops and a Regulator of RNaseH1

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In Vivo Amelioration of Age-Associated Hallmarks by Partial Reprogramming

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MATE transport of the E. coli-derived genotoxin colibactin

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