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  1. Jan 2020
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    Unique and Shared Epigenetic Programs of the CREBBP and EP300 Acetyltransferases in Germinal Center B Cells Reveal Targetable Dependencies in Lymphoma
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    MeCP2 Represses Enhancers through Chromosome Topology-Associated DNA Methylation
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    Glucose Metabolism Drives Histone Acetylation Landscape Transitions that Dictate Muscle Stem Cell Function
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    Genomic Resolution of DLX-Orchestrated Transcriptional Circuits Driving Development of Forebrain GABAergic Neurons
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    Enhancer Domains in Gastrointestinal Stromal Tumor Regulate KIT Expression and Are Targetable by BET Bromodomain Inhibition
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    Functional Enhancers Shape Extrachromosomal Oncogene Amplifications
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    Dynamic Enhancer DNA Methylation as Basis for Transcriptional and Cellular Heterogeneity of ESCs
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    Natural molecules induce and synergize to boost expression of the human antimicrobial peptide β-defensin-3
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    Brd4 and P300 Confer Transcriptional Competency during Zygotic Genome Activation
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    Heterozygous Mutations in SMARCA2 Reprogram the Enhancer Landscape by Global Retargeting of SMARCA4
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    The RNA Helicase DDX6 Controls Cellular Plasticity by Modulating P-Body Homeostasis
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    Reconstruction of the Global Neural Crest Gene Regulatory Network In Vivo
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    BCL2 Amplicon Loss and Transcriptional Remodeling Drives ABT-199 Resistance in B Cell Lymphoma Models
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    Direct Induction of the Three Pre-implantation Blastocyst Cell Types from Fibroblasts
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    Stem Cell Proliferation Is Kept in Check by the Chromatin Regulators Kismet/CHD7/CHD8 and Trr/MLL3/4
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    Impaired LXRα Phosphorylation Attenuates Progression of Fatty Liver Disease
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    BRD4 directs hematopoietic stem cell development and modulates macrophage inflammatory responses
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    Tracing MYC Expression for Small Molecule Discovery
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    Histone Acetyltransferase p300 Induces De Novo Super-Enhancers to Drive Cellular Senescence
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    De Novo PITX1 Expression Controls Bi-Stable Transcriptional Circuits to Govern Self-Renewal and Differentiation in Squamous Cell Carcinoma
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    Mapping the Global Chromatin Connectivity Network for Sox2 Function in Neural Stem Cell Maintenance
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    The Nuclear Receptor PPARγ Controls Progressive Macrophage Polarization as a Ligand-Insensitive Epigenomic Ratchet of Transcriptional Memory
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    17β-Estradiol and ICI182,780 Differentially Regulate STAT5 Isoforms in Female Mammary Epithelium, With Distinct Outcomes
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    Overcoming Resistance to Dual Innate Immune and MEK Inhibition Downstream of KRAS
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    The Evf2 Ultraconserved Enhancer lncRNA Functionally and Spatially Organizes Megabase Distant Genes in the Developing Forebrain
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    Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses
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    A Chromatin Basis for Cell Lineage and Disease Risk in the Human Pancreas
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    Neutralizing Gatad2a-Chd4-Mbd3/NuRD Complex Facilitates Deterministic Induction of Naive Pluripotency
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    Architectural Proteins and Pluripotency Factors Cooperate to Orchestrate the Transcriptional Response of hESCs to Temperature Stress
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    Cooperative Enhancer Activation by TLX1 and STAT5 Drives Development of NUP214-ABL1/TLX1-Positive T Cell Acute Lymphoblastic Leukemia
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    Multisite Substrate Recognition in Asf1-Dependent Acetylation of Histone H3 K56 by Rtt109
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    Diet-Induced Circadian Enhancer Remodeling Synchronizes Opposing Hepatic Lipid Metabolic Processes
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    Targeting the HTLV-I-Regulated BATF3/IRF4 Transcriptional Network in Adult T Cell Leukemia/Lymphoma
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    GRHL2-Dependent Enhancer Switching Maintains a Pluripotent Stem Cell Transcriptional Subnetwork after Exit from Naive Pluripotency
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    Marked Diversity of Unique Cortical Enhancers Enables Neuron-Specific Tools by Enhancer-Driven Gene Expression
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    The Nucleosome Remodeling and Deacetylation Complex Modulates Chromatin Structure at Sites of Active Transcription to Fine-Tune Gene Expression
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    Epigenetic drift of H3K27me3 in aging links glycolysis to healthy longevity in Drosophila
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    MLL4 Is Required to Maintain Broad H3K4me3 Peaks and Super-Enhancers at Tumor Suppressor Genes
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    Exit from Naive Pluripotency Induces a Transient X Chromosome Inactivation-like State in Males
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    Programming of Schwann Cells by Lats1/2-TAZ/YAP Signaling Drives Malignant Peripheral Nerve Sheath Tumorigenesis
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    Transformation of Accessible Chromatin and 3D Nucleome Underlies Lineage Commitment of Early T Cells
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    The Epigenetic State of PRDM16-Regulated Enhancers in Radial Glia Controls Cortical Neuron Position
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    A Linc1405/Eomes Complex Promotes Cardiac Mesoderm Specification and Cardiogenesis
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    Chromatin Accessibility Dynamics during iPSC Reprogramming
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    Promoter of lncRNA Gene PVT1 Is a Tumor-Suppressor DNA Boundary Element
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    PRC1 Fine-tunes Gene Repression and Activation to Safeguard Skin Development and Stem Cell Specification
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    A Non-catalytic Function of SETD1A Regulates Cyclin K and the DNA Damage Response
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    BRD4 Inhibition Is Synthetic Lethal with PARP Inhibitors through the Induction of Homologous Recombination Deficiency
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    LKB1, Salt-Inducible Kinases, and MEF2C Are Linked Dependencies in Acute Myeloid Leukemia
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    Histone Deacetylases 1 and 2 Regulate Microglia Function during Development, Homeostasis, and Neurodegeneration in a Context-Dependent Manner
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    Chromatin Accessibility Dynamics during Chemical Induction of Pluripotency
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    A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment
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    Different Neuronal Activity Patterns Induce Different Gene Expression Programs
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  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bladder-cancer-associated mutations in RXRA activate peroxisome proliferator-activated receptors to drive urothelial proliferation
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    AP-1 Transcription Factors and the BAF Complex Mediate Signal-Dependent Enhancer Selection
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    Activation of the Notch Signaling Pathway In Vivo Elicits Changes in CSL Nuclear Dynamics
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    Dual Targeting of Oncogenic Activation and Inflammatory Signaling Increases Therapeutic Efficacy in Myeloproliferative Neoplasms
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    The Transcription Factor STAT6 Mediates Direct Repression of Inflammatory Enhancers and Limits Activation of Alternatively Polarized Macrophages
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    CRISPR-Based Chromatin Remodeling of the Endogenous Oct4 or Sox2 Locus Enables Reprogramming to Pluripotency
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    Cohesin Loss Eliminates All Loop Domains
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    The Elongation Factor Spt6 Maintains ESC Pluripotency by Controlling Super-Enhancers and Counteracting Polycomb Proteins
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    CBP Regulates Recruitment and Release of Promoter-Proximal RNA Polymerase II
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    Zfp281 is essential for mouse epiblast maturation through transcriptional and epigenetic control of Nodal signaling
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    Early-Life Gene Expression in Neurons Modulates Lasting Epigenetic States
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    Aberrant Activation of a Gastrointestinal Transcriptional Circuit in Prostate Cancer Mediates Castration Resistance
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    H3.3K27M Cooperates with Trp53 Loss and PDGFRA Gain in Mouse Embryonic Neural Progenitor Cells to Induce Invasive High-Grade Gliomas
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  106. Nov 2017
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    Role of the Astroglial Glutamate Exchanger xCT in Ventral Hippocampus in Resilience to Stress
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    CTCF-Mediated Enhancer-Promoter Interaction Is a Critical Regulator of Cell-to-Cell Variation of Gene Expression
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    Static and Dynamic DNA Loops form AP-1-Bound Activation Hubs during Macrophage Development
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  110. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Epigenetic mechanisms underlying NMDA receptor hypofunction in the prefrontal cortex of juvenile animals in the MAM model for schizophrenia
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    In Situ Capture of Chromatin Interactions by Biotinylated dCas9
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    Evolutionarily Conserved Principles Predict 3D Chromatin Organization
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    Myc Regulates Chromatin Decompaction and Nuclear Architecture during B Cell Activation
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    Circadian Reprogramming in the Liver Identifies Metabolic Pathways of Aging
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    Enhancer Reprogramming Promotes Pancreatic Cancer Metastasis
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    A UTX-MLL4-p300 Transcriptional Regulatory Network Coordinately Shapes Active Enhancer Landscapes for Eliciting Transcription
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  117. genomemedicine.biomedcentral.com genomemedicine.biomedcentral.com
    Identification and characterization of a FOXA2-regulated transcriptional enhancer at a type 2 diabetes intronic locus that controls GCKR expression in liver cells
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    BET Bromodomain Proteins Function as Master Transcription Elongation Factors Independent of CDK9 Recruitment
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    The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis
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    Dynamic Rewiring of Promoter-Anchored Chromatin Loops during Adipocyte Differentiation
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    The Transcription Factor T-bet Limits Amplification of Type I IFN Transcriptome and Circuitry in T Helper 1 Cells
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  122. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mice deficient of Myc super-enhancer region reveal differential control mechanism between normal and pathological growth
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    Genomic Characterization of Murine Monocytes Reveals C/EBPβ Transcription Factor Dependence of Ly6C− Cells
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  124. academic.oup.com academic.oup.com
    Inverse Regulation of DHT Synthesis Enzymes 5α-Reductase Types 1 and 2 by the Androgen Receptor in Prostate Cancer
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  125. academic.oup.com academic.oup.com
    Thyroid Hormone-Dependent Epigenetic Regulation of Melanocortin 4 Receptor Levels in Female Offspring of Obese Rats
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    academic.oup.com/endo/article/158/4/842/2877139/Thyroid-Hormone-Dependent-Epigenetic-Regulation-of
  126. www.sciencedirect.com www.sciencedirect.com
    Polycomb Repressive Complex 2-Mediated Chromatin Repression Guides Effector CD8+ T Cell Terminal Differentiation and Loss of Multipotency
    1
    1. scibot 08 Nov 2017
      AB_2118291

      Curator: @kaitlinsung

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    sciencedirect.com/science/article/pii/S107476131730122X
  127. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ciliary transcription factors and miRNAs precisely regulate Cp110 levels required for ciliary adhesions and ciliogenesis
    1
    1. scibot 08 Nov 2017
      H3K27ac

      Curator: @chewbeccax

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      (Abcam Cat# ab4729, RRID:AB_2118291)

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      RRID:AB_2118291 RRIDCUR:Missing
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    ncbi.nlm.nih.gov/pmc/articles/PMC5045295/
  128. www.sciencedirect.com www.sciencedirect.com
    ERK-Induced Activation of TCF Family of SRF Cofactors Initiates a Chromatin Modification Cascade Associated with Transcription
    1
    1. scibot 08 Nov 2017
      AB_2118291

      Curator: @chewbeccax

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      (Abcam Cat# ab4729, RRID:AB_2118291)

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    sciencedirect.com/science/article/pii/S1097276517300977
  129. www.sciencedirect.com www.sciencedirect.com
    Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis
    1
    1. scibot 08 Nov 2017
      AB_2118291

      Curator: @gabimpine

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      (Abcam Cat# ab4729, RRID:AB_2118291)

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    sciencedirect.com/science/article/pii/S0002929716305201
  130. www.sciencedirect.com www.sciencedirect.com
    An Hdac1/Rpd3-Poised Circuit Balances Continual Self-Renewal and Rapid Restriction of Developmental Potential during Asymmetric Stem Cell Division
    1
    1. scibot 08 Nov 2017
      AB_2118291

      Curator: @Zeljana_Babic

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    sciencedirect.com/science/article/pii/S1534580717300412
  131. www.sciencedirect.com www.sciencedirect.com
    Distinct Roles of Brd2 and Brd4 in Potentiating the Transcriptional Program for Th17 Cell Differentiation
    1
    1. scibot 08 Nov 2017
      AB_2118291

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    sciencedirect.com/science/article/pii/S1097276516308656
  132. www.sciencedirect.com www.sciencedirect.com
    Epigenetic Activation of WNT5A Drives Glioblastoma Stem Cell Differentiation and Invasive Growth
    1
    1. scibot 08 Nov 2017
      AB_2118291

      Curator: @chewbeccax

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      (Abcam Cat# ab4729, RRID:AB_2118291)

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    sciencedirect.com/science/article/pii/S009286741631460X
  133. www.sciencedirect.com www.sciencedirect.com
    Transcriptional Networks Controlled by NKX2-1 in the Development of Forebrain GABAergic Neurons
    1
    1. scibot 08 Nov 2017
      AB_2118291

      Curator: @chewbeccax

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      (Abcam Cat# ab4729, RRID:AB_2118291)

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    sciencedirect.com/science/article/pii/S0896627316305128
  134. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptional Networks Controlled by NKX2-1 in the Development of Forebrain GABAergic Neurons
    1
    1. scibot 08 Nov 2017
      AB_2118291

      Curator: @chewbeccax

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      (Abcam Cat# ab4729, RRID:AB_2118291)

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    ncbi.nlm.nih.gov/pmc/articles/PMC5319854/
  135. www.sciencedirect.com www.sciencedirect.com
    Not All H3K4 Methylations Are Created Equal: Mll2/COMPASS Dependency in Primordial Germ Cell Specification
    1
    1. scibot 08 Nov 2017
      ab4729

      Curator: @kaitlinsung

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      (Abcam Cat# ab4729, RRID:AB_2118291)

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    sciencedirect.com/science/article/pii/S1097276517300394
  136. www.sciencedirect.com www.sciencedirect.com
    Expression of Terminal Effector Genes in Mammalian Neurons Is Maintained by a Dynamic Relay of Transient Enhancers
    1
    1. scibot 08 Nov 2017
      AB_2118291

      Curator: @gabimpine

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      (Abcam Cat# ab4729, RRID:AB_2118291)

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    sciencedirect.com/science/article/pii/S0896627316309059
  137. www.sciencedirect.com www.sciencedirect.com
    Multi-tiered Reorganization of the Genome during B Cell Affinity Maturation Anchored by a Germinal Center-Specific Locus Control Region
    1
    1. scibot 08 Nov 2017
      RRID: AB_2118291

      Curator: @chewbeccax

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      (Abcam Cat# ab4729, RRID:AB_2118291)

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    sciencedirect.com/science/article/pii/S1074761316303363
  138. www.sciencedirect.com www.sciencedirect.com
    Microbiota Diurnal Rhythmicity Programs Host Transcriptome Oscillations
    1
    1. scibot 08 Nov 2017
      AB_2118291

      Curator: @chewbeccax

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      (Abcam Cat# ab4729, RRID:AB_2118291)

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    sciencedirect.com/science/article/pii/S0092867416315240
  139. www.sciencedirect.com www.sciencedirect.com
    A Multi-step Transcriptional and Chromatin State Cascade Underlies Motor Neuron Programming from Embryonic Stem Cells
    1
    1. scibot 08 Nov 2017
      AB_2118291

      Curator: @gabimpine

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      (Abcam Cat# ab4729, RRID:AB_2118291)

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    sciencedirect.com/science/article/pii/S1934590916304027
  140. www.sciencedirect.com www.sciencedirect.com
    LRP8-Reelin-Regulated Neuronal Enhancer Signature Underlying Learning and Memory Formation
    1
    1. scibot 08 Nov 2017
      AB_2118291

      Curator: @gabimpine

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      (Abcam Cat# ab4729, RRID:AB_2118291)

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    sciencedirect.com/science/article/pii/S0896627315002573