611 Matching Annotations
  1. Jul 2021
  2. www.sciencedirect.com www.sciencedirect.com
    Neuron-Specific Genome Modification in the Adult Rat Brain Using CRISPR-Cas9 Transgenic Rats
    1
    1. scibot 31 Jul 2021
      RRID:AB_2242334

      DOI: 10.1016/j.neuron.2019.01.035

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    sciencedirect.com/science/article/pii/S0896627319300625
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    1. scibot 31 Jul 2021
      RRID:AB_2242334

      DOI: 10.7554/eLife.43511

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    ncbi.nlm.nih.gov/pmc/articles/PMC6414201/
  4. www.nature.com www.nature.com
    Dominant-negative ATF5 rapidly depletes survivin in tumor cells
    1
    1. scibot 30 Jul 2021
      mouse anti-ACTIN

      DOI: 10.1038/s41419-019-1872-y

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    nature.com/articles/s41419-019-1872-y
  5. academic.oup.com academic.oup.com
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    1. scibot 30 Jul 2021
      AB_2242334

      DOI: 10.1210/en.2017-00152

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    academic.oup.com/endo/article/158/8/2543/3836962
  6. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Akt3-mTOR regulates hippocampal neurogenesis in adult mouse
    1
    1. scibot 29 Jul 2021
      RRID:AB_2242334

      DOI: 10.1111/jnc.15441

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15441
  7. academic.oup.com academic.oup.com
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    1. scibot 29 Jul 2021
      RRID:AB_2242334

      DOI: 10.1210/en.2017-03017

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    academic.oup.com/endo/article/159/1/465/4630300
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    A structure-specific small molecule inhibits a miRNA-200 family member precursor and reverses a type 2 diabetes phenotype
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    1. scibot 28 Jul 2021
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      DOI: 10.1016/j.chembiol.2021.07.006

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    sciencedirect.com/science/article/pii/S2451945621003160
  9. academic.oup.com academic.oup.com
    Lack of Lrp5 Signaling in Osteoblasts Sensitizes Male Mice to Diet-Induced Disturbances in Glucose Metabolism
    2
    1. scibot 28 Jul 2021
      AB_2242334

      DOI: 10.1210/en.2017-00657

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    2. scibot 27 Jul 2021
      RRID: AB_2242334

      DOI: 10.1210/en.2017-00657

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    academic.oup.com/endo/article/158/11/3805/4117224
  10. www.sciencedirect.com www.sciencedirect.com
    A Brucella Type IV Effector Targets the COG Tethering Complex to Remodel Host Secretory Traffic and Promote Intracellular Replication
    2
    1. scibot 28 Jul 2021
      RRID:AB_2242334

      DOI: 10.1016/j.chom.2017.07.017

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    2. scibot 28 Jul 2021
      RRID:AB_2242334

      DOI: 10.1016/j.chom.2017.07.017

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    sciencedirect.com/science/article/pii/S1931312817303001
  11. academic.oup.com academic.oup.com
    Glucose Transporter-4 Facilitates Insulin-Stimulated Glucose Uptake in Osteoblasts
    2
    1. scibot 27 Jul 2021
      AB_2242334u00a0

      DOI: 10.1210/en.2016-1583

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    2. scibot 27 Jul 2021
      u03b2-actin (3700, AB_2242334)

      DOI: 10.1210/en.2016-1583

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    academic.oup.com/endo/article/157/11/4094/2758329/Glucose-Transporter-4-Facilitates-Insulin
  12. www.sciencedirect.com www.sciencedirect.com
    Mitophagy Controls the Activities of Tumor Suppressor p53 to Regulate Hepatic Cancer Stem Cells
    1
    1. scibot 27 Jul 2021
      RRID:AB_2242334

      DOI: 10.1016/j.molcel.2017.09.022

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    sciencedirect.com/science/article/pii/S1097276517307001
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 27 Jul 2021
      RRID:AB_10828322

      DOI: 10.1016/j.ebiom.2016.06.041

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    ncbi.nlm.nih.gov/pmc/articles/PMC5006644/
  14. www.ebiomedicine.com www.ebiomedicine.com
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    1. scibot 27 Jul 2021
      RRID:AB_10828322

      DOI: 10.1016/j.ebiom.2016.06.041

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      Curator: @Naa003

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      Curator comments: Beta-Actin (8H10D10) Mouse MAb Antibody Cell Signaling Technology Cat# 3700 also 3700P, 3700S

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    ebiomedicine.com/article/S2352-3964(16)30298-5/abstract
  15. www.sciencedirect.com www.sciencedirect.com
    Nicotinamide phosphoribosyltransferase inhibitors selectively induce apoptosis of AML stem cells by disrupting lipid homeostasis
    1
    1. scibot 22 Jul 2021
      RRID:AB_2242334

      DOI: 10.1016/j.stem.2021.06.004

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    sciencedirect.com/science/article/pii/S1934590921002745
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    Control of gasdermin D oligomerization and pyroptosis by the Ragulator-Rag-mTORC1 pathway
    1
    1. scibot 22 Jul 2021
      RRID:AB_2242334

      DOI: 10.1016/j.cell.2021.06.028

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    sciencedirect.com/science/article/pii/S0092867421007960
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Generation of glucocorticoid resistant SARS-CoV-2 T-cells for adoptive cell therapy
    1
    1. scibot 17 Jul 2021
      RRID:AB_2242334

      DOI: 10.1016/j.celrep.2021.109432

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    ncbi.nlm.nih.gov/pmc/articles/PMC8260499/
  18. www.sciencedirect.com www.sciencedirect.com
    Regulatory variants in TCF7L2 are associated with thoracic aortic aneurysm
    1
    1. scibot 15 Jul 2021
      3700

      DOI: 10.1016/j.ajhg.2021.06.016

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    sciencedirect.com/science/article/pii/S0002929721002408
  19. www.sciencedirect.com www.sciencedirect.com
    Modulation of Akt vs Stat3 activity by the focal adhesion kinase in non-neoplastic mouse fibroblasts
    1
    1. scibot 15 Jul 2021
      Cell-signalling technology Cat. #3700

      DOI: 10.1016/j.yexcr.2021.112731

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    sciencedirect.com/science/article/pii/S0014482721002639
  20. Jun 2021
  21. cancerdiscovery.aacrjournals.org cancerdiscovery.aacrjournals.org
    LKB1/STK11 is a tumor suppressor in the progression of myeloproliferative neoplasms
    1
    1. scibot 29 Jun 2021
      RRID:AB_2242334

      DOI: 10.1158/2159-8290.CD-20-1353

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    cancerdiscovery.aacrjournals.org/content/11/6/1398
  22. cancerdiscovery.aacrjournals.org cancerdiscovery.aacrjournals.org
    TNIK is a therapeutic target in Lung Squamous Cell Carcinoma and regulates FAK activation through Merlin.
    1
    1. scibot 29 Jun 2021
      RRID:AB_2242334

      DOI: 10.1158/2159-8290.CD-20-0797

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    cancerdiscovery.aacrjournals.org/content/11/6/1411
  23. www.sciencedirect.com www.sciencedirect.com
    The glutathione peroxidase Gpx4 prevents lipid peroxidation and ferroptosis to sustain Treg cell activation and suppression of antitumor immunity
    1
    1. scibot 16 Jun 2021
      RRID:AB_2242334

      DOI: 10.1016/j.celrep.2021.109235

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    sciencedirect.com/science/article/pii/S2211124721005945
  24. elifesciences.org elifesciences.org
    PHAROH lncRNA regulates Myc translation in hepatocellular carcinoma via sequestering TIAR
    1
    1. scibot 05 Jun 2021
      RRID:AB_2242334

      DOI: 10.7554/eLife.68263

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    elifesciences.org/articles/68263
  25. www.sciencedirect.com www.sciencedirect.com
    Cytoplasmic RAD23B interacts with CORO1C to synergistically promote colorectal cancer progression and metastasis
    1
    1. scibot 02 Jun 2021
      3700s

      DOI: 10.1016/j.canlet.2021.05.033

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    sciencedirect.com/science/article/pii/S0304383521002573
  26. May 2021
  27. onlinelibrary.wiley.com onlinelibrary.wiley.com
    MicroRNA-3473b regulates the expression of TREM2/ULK1 and inhibits autophagy in inflammatory pathogenesis of Parkinson disease
    1
    1. scibot 20 May 2021
      RRID:AB_2242334

      DOI: 10.1111/jnc.15299

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15299
  28. www.sciencedirect.com www.sciencedirect.com
    Viral tegument proteins restrict cGAS-DNA phase separation to mediate immune evasion
    1
    1. scibot 20 May 2021
      RRID:AB_2242334

      DOI: 10.1016/j.molcel.2021.05.002

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    sciencedirect.com/science/article/pii/S1097276521003592
  29. www.sciencedirect.com www.sciencedirect.com
    MeCP2 controls neural stem cell fate specification through miR-199a-mediated inhibition of BMP-Smad signaling
    1
    1. scibot 19 May 2021
      RRID:AB_2242334

      DOI: 10.1016/j.celrep.2021.109124

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    sciencedirect.com/science/article/pii/S2211124721004630
  30. www.sciencedirect.com www.sciencedirect.com
    Helicobacter pylori CagA elicits BRCAness to induce genome instability that may underlie bacterial gastric carcinogenesis
    1
    1. scibot 14 May 2021
      RRID:AB_2242334

      DOI: 10.1016/j.chom.2021.04.006

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    sciencedirect.com/science/article/pii/S1931312821001827
  31. www.sciencedirect.com www.sciencedirect.com
    RhoA/Cdc42 signaling drives cytoplasmic maturation but not endomitosis in megakaryocytes
    1
    1. scibot 12 May 2021
      RRID:AB_2242334

      DOI: 10.1016/j.celrep.2021.109102

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    sciencedirect.com/science/article/pii/S2211124721004368
  32. www.sciencedirect.com www.sciencedirect.com
    Glycolytic ATP fuels phosphoinositide 3-kinase signaling to support effector T helper 17 cell responses
    1
    1. scibot 12 May 2021
      RRID:AB_2242334

      DOI: 10.1016/j.immuni.2021.04.008

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    sciencedirect.com/science/article/pii/S1074761321001709
  33. journals.physiology.org journals.physiology.org
    MARCKS-Like Protein-1(MLP-1) regulates ENaC Activity in Renal Distal Convoluted Tubule Cells
    1
    1. scibot 10 May 2021
      RRID:AB_2242334

      DOI: 10.1152/ajpcell.00218.2020

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    journals.physiology.org/doi/abs/10.1152/ajpcell.00218.2020
  34. rupress.org rupress.org
    Loss of tRNA-modifying enzyme Elp3 activates a p53-dependent antitumor checkpoint in hematopoiesis
    1
    1. scibot 09 May 2021
      RRID:AB_2242334

      DOI: 10.1084/jem.20200662

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    rupress.org/jem/article/218/3/e20200662/211733/Loss-of-tRNA-modifying-enzyme-Elp3-activates-a-p53
  35. www.sciencedirect.com www.sciencedirect.com
    LEFTY1 Is a Dual-SMAD Inhibitor that Promotes Mammary Progenitor Growth and Tumorigenesis
    1
    1. scibot 09 May 2021
      RRID:AB_2242334

      DOI: 10.1016/j.stem.2020.06.017

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    sciencedirect.com/science/article/pii/S1934590920302848
  36. www.sciencedirect.com www.sciencedirect.com
    Reciprocal communication between astrocytes and endothelial cells is required for astrocytic glutamate transporter 1 (GLT-1) expression
    1
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      RRID:AB_2242334

      DOI: 10.1016/j.neuint.2020.104787

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    sciencedirect.com/science/article/pii/S0197018620301789
  37. www.sciencedirect.com www.sciencedirect.com
    Stabilization of ERK-Phosphorylated METTL3 by USP5 Increases m6A Methylation
    1
    1. scibot 08 May 2021
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      DOI: 10.1016/j.molcel.2020.10.026

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    sciencedirect.com/science/article/pii/S1097276520307334
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    Tumor Interferon Signaling Is Regulated by a lncRNA INCR1 Transcribed from the PD-L1 Locus
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    1. scibot 07 May 2021
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      DOI: 10.1016/j.molcel.2020.05.015

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    sciencedirect.com/science/article/pii/S1097276520303166
  39. www.sciencedirect.com www.sciencedirect.com
    Heparin prevents caspase-11-dependent septic lethality independent of anticoagulant properties
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    1. scibot 07 May 2021
      RRID:AB_2242334

      DOI: 10.1016/j.immuni.2021.01.007

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    sciencedirect.com/science/article/pii/S1074761321000303
  40. www.sciencedirect.com www.sciencedirect.com
    Caspase-8-Dependent Inflammatory Responses Are Controlled by Its Adaptor, FADD, and Necroptosis
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    1. scibot 06 May 2021
      RRID:AB_2242334

      DOI: 10.1016/j.immuni.2020.04.010

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    sciencedirect.com/science/article/pii/S1074761320301680
  41. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    1. scibot 06 May 2021
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      DOI: 10.1002/1878-0261.12953

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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.12953
  42. www.sciencedirect.com www.sciencedirect.com
    Malic enzyme 2 connects the Krebs cycle intermediate fumarate to mitochondrial biogenesis
    1
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  83. Nov 2020
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    Loss of Muscle Carnitine Palmitoyltransferase 2 Prevents Diet-Induced Obesity and Insulin Resistance despite Long-Chain Acylcarnitine Accumulation
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    CTCF-Mediated Genome Architecture Regulates the Dosage of Mitotically Stable Mono-allelic Expression of Autosomal Genes
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  86. Oct 2020
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    Heterotrimeric G‐protein, Gi1, is involved in the regulation of proliferation, neuronal migration and dendrite morphology during cortical development in vivo
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    Persistent DNA Damage and Senescence in the Placenta Impacts Developmental Outcomes of Embryos
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  89. Sep 2020
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    Blockade of Oncogenic NOTCH1 with the SERCA Inhibitor CAD204520 in T Cell Acute Lymphoblastic Leukemia
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    The Set7 Lysine Methyltransferase Regulates Plasticity in Oxidative Phosphorylation Necessary for Trained Immunity Induced by β-Glucan
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    TMEM173 Drives Lethal Coagulation in Sepsis
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    FKBP10 Regulates Protein Translation to Sustain Lung Cancer Growth
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    Selective Neuronal Vulnerability in Alzheimer’s Disease: A Network-Based Analysis
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  95. onlinelibrary.wiley.com onlinelibrary.wiley.com
    GDF15 promotes simultaneous astrocyte remodeling and tight junction strengthening at the blood–brain barrier
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      DOI: 10.1002/jnr.24611

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  96. www.sciencedirect.com www.sciencedirect.com
    A Live-Cell Screen for Altered Erk Dynamics Reveals Principles of Proliferative Control
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    A Non-structural 1 Protein G53D Substitution Attenuates a Clinically Tested Live Dengue Vaccine
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      DOI: 10.1016/j.celrep.2020.107617

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  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hepatitis Delta Virus histone mimicry drives the recruitment of chromatin remodelers for viral RNA replication
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  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GLUT1-mediated glycolysis supports GnRH-induced secretion of luteinizing hormone from female gonadotropes
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      DOI: 10.1038/s41598-020-69913-z

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  100. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    In utero inflammatory challenge induces an early activation of the hepatic innate immune response in late gestation fetal sheep - Miguel A Zarate, Stephanie R Wesolowski, Leanna M Nguyen, Robyn K De Dios, Randall B Wilkening, Paul J Rozance, Clyde J Wright,
    2
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    A dysregulated bile acid-gut microbiota axis contributes to obesity susceptibility
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    Metformin Enhances Autophagy and Normalizes Mitochondrial Function to Alleviate Aging-Associated Inflammation
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      DOI: 10.1016/j.cmet.2020.04.015

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    FBXL5 Regulates IRP2 Stability in Iron Homeostasis via an Oxygen-Responsive [2Fe2S] Cluster
    1
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      DOI: 10.1016/j.molcel.2020.02.011

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    Small Molecule Dysregulation of TEAD Lipidation Induces a Dominant-Negative Inhibition of Hippo Pathway Signaling
    1
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      DOI: 10.1016/j.celrep.2020.107809

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  105. mcr.aacrjournals.org mcr.aacrjournals.org
    Ceramide analog SACLAC modulates sphingolipid levels and Mcl-1 splicing to induce apoptosis in acute myeloid leukemia
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      AB_2242334

      DOI: 10.1158/1541-7786.MCR-19-0619

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  106. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Sirtuin 3 is required for the protective effect of Resveratrol on Manganese‐induced disruption of mitochondrial biogenesis in primary cultured neurons
    1
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      RRID:AB_2242334

      DOI: 10.1111/jnc.15095

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15095
  107. www.sciencedirect.com www.sciencedirect.com
    Inhibition of MEK1/2 Forestalls the Onset of Acquired Resistance to Entrectinib in Multiple Models of NTRK1-Driven Cancer
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      RRID:AB_2242334

      DOI: 10.1016/j.celrep.2020.107994

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    sciencedirect.com/science/article/pii/S2211124720309797
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    RNA Demethylase ALKBH5 Selectively Promotes Tumorigenesis and Cancer Stem Cell Self-Renewal in Acute Myeloid Leukemia
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      RRID:AB_2242334

      DOI: 10.1016/j.stem.2020.04.009

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    sciencedirect.com/science/article/pii/S193459092030148X
  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Piezo1/2 mediate mechanotransduction essential for bone formation through concerted activation of NFAT-YAP1-ß-catenin
    1
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      RRID:AB_2242334

      DOI: 10.7554/eLife.52779

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    ncbi.nlm.nih.gov/pmc/articles/PMC7112954/
  110. onlinelibrary.wiley.com onlinelibrary.wiley.com
    KIF15 promotes the evolution of gastric cancer cells through inhibition of reactive oxygen species‐mediated apoptosis
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      RRID:AB_2242334

      DOI: 10.1002/jcp.29743

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    onlinelibrary.wiley.com/doi/10.1002/jcp.29743
  111. onlinelibrary.wiley.com onlinelibrary.wiley.com
    High‐frequency transcranial magnetic stimulation protects APP/PS1 mice against Alzheimer’s disease progress by reducing APOE and enhancing autophagy
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      RRID:AB_2242334

      DOI: 10.1002/brb3.1740

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  112. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      RRID:AB_2242334

      DOI: 10.1111/bph.14918

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  113. www.cell.com www.cell.com
    A Genome-wide ER-phagy Screen Highlights Key Roles of Mitochondrial Metabolism and ER-Resident UFMylation
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      DOI: 10.1016/j.cell.2020.02.017

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    cell.com/cell/fulltext/S0092-8674(20)30161-6
  114. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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      RRID:AB_2242334

      DOI: 10.1111/bph.15080

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  115. www.cell.com www.cell.com
    NF-κB Dynamics Discriminate between TNF Doses in Single Cells
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      RRID: AB_2242334

      DOI: 10.1016/j.cels.2017.10.011

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    cell.com/cell-systems/abstract/S2405-4712(17)30448-9
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    OVA66 promotes tumour angiogenesis and progression through enhancing autocrine VEGF-VEGFR2 signalling
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      RRID: AB_2242334

      DOI: 10.1016/j.ebiom.2019.02.051

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  117. rupress.org rupress.org
    Genetic manipulation of LKB1 elicits lethal metastatic prostate cancer
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      β-actin

      DOI: 10.1084/jem.20191787

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  118. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Novel role for CRK adaptor proteins as essential components of SRC/FAK signaling for epithelial‐mesenchymal transition and colorectal cancer aggressiveness
    1
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      β‐actin

      DOI: 10.1002/ijc.32955

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    onlinelibrary.wiley.com/doi/10.1002/ijc.32955
  119. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A marine fungus‐derived nitrobenzoyl sesquiterpenoid suppresses RANKL‐induced osteoclastogenesis and attenuates inflammatory bone destruction
    1
    1. scibot 03 Sep 2020
      RRID:AB_2242334

      DOI: 10.1111/bph.15179

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  120. mcr.aacrjournals.org mcr.aacrjournals.org
    Dual Regulation of Histone Methylation by mTOR Complexes Controls Glioblastoma Tumor Cell Growth via EZH2 and SAM
    1
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      β-actin

      DOI: 10.1158/1541-7786.MCR-20-0024

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  121. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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      anti‐mouse β‐Actin

      DOI: 10.1111/bph.15149

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15149
  122. elifesciences.org elifesciences.org
    A non-canonical role for the EDC4 decapping factor in regulating MARF1-mediated mRNA decay
    1
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      Anti-human Actin Mouse monoclonal

      DOI: 10.7554/eLife.54995

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    elifesciences.org/articles/54995
  123. www.sciencedirect.com www.sciencedirect.com
    Islet O-GlcNAcylation Is Required for Lipid Potentiation of Insulin Secretion through SERCA2
    1
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      RRID:AB_2242334

      DOI: 10.1016/j.celrep.2020.107609

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  124. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ER-luminal [Ca2+] regulation of InsP3 receptor gating mediated by an ER-luminal peripheral Ca2+-binding protein
    1
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      RRID:AB_2242334

      DOI: 10.7554/eLife.53531

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    ncbi.nlm.nih.gov/pmc/articles/PMC7259957/
  125. Aug 2020
  126. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Dopaminergic afferents from midbrain to dorsolateral bed nucleus of stria terminalis inhibit release and expression of corticotropin‐releasing hormone in paraventricular nucleus
    1
    1. scibot 23 Aug 2020
      AB_10828322

      DOI: 10.1111/jnc.14992

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    onlinelibrary.wiley.com/doi/10.1111/jnc.14992
  127. Jan 2020
  128. www.frontiersin.org www.frontiersin.org
    Calcium-Sensing Receptor Is Functionally Expressed in the Cochlear Perilymphatic Compartment and Essential for Hearing
    1
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      RRID:AB_2242334

      DOI: 10.3389/fnmol.2019.00175

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    Melleolides from Honey Mushroom Inhibit 5-Lipoxygenase via Cys159
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    Hand2 Selectively Reorganizes Chromatin Accessibility to Induce Pacemaker-like Transcriptional Reprogramming
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    Pharmacological Induction of RAS-GTP Confers RAF Inhibitor Sensitivity in KRAS Mutant Tumors
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    Proteomics, Post-translational Modifications, and Integrative Analyses Reveal Molecular Heterogeneity within Medulloblastoma Subgroups
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    A high-throughput screen of real-time ATP levels in individual cells reveals mechanisms of energy failure
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    SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function
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    Aerobic Glycolysis Controls Myeloid-Derived Suppressor Cells and Tumor Immunity via a Specific CEBPB Isoform in Triple-Negative Breast Cancer
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    Global Analysis of Plasma Lipids Identifies Liver-Derived Acylcarnitines as a Fuel Source for Brown Fat Thermogenesis
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    Brain endothelial cells induce astrocytic expression of the glutamate transporter GLT‐1 by a Notch‐dependent mechanism
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