566 Matching Annotations
  1. Jul 2022
  2. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Potassium channel Kir4.1 regulates oligodendrocyte differentiation via intracellular pH regulation
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    onlinelibrary.wiley.com/doi/10.1002/glia.24240
  3. Jun 2022
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    An oncogenic JMJD6-DGAT1 axis tunes the epigenetic regulation of lipid droplet formation in clear cell renal cell carcinoma
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    sciencedirect.com/science/article/pii/S1097276522005391
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    Inter-subunit crosstalk via PDZ synergistically governs allosteric activation of proapoptotic HtrA2
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    sciencedirect.com/science/article/pii/S0969212622002325
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    A function for Ataxia telangiectasia and Rad3-related (ATR) kinase in cytokinetic abscission
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    sciencedirect.com/science/article/pii/S2589004222008070
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    Indoleamine 2,3-dioxygenase 1 activation in mature cDC1 promotes tolerogenic education of inflammatory cDC2 via metabolic communication
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    sciencedirect.com/science/article/pii/S1074761322002333
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    A stromal Integrated Stress Response activates perivascular cancer-associated fibroblasts to drive angiogenesis and tumour progression
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    nature.com/articles/s41556-022-00918-8
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    Interspecies commensal interactions have nonlinear impacts on host immunity
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    sciencedirect.com/science/article/pii/S1931312822002645
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    Muscle satellite cells are impaired in type 2 diabetic mice by elevated extracellular adenosine
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    sciencedirect.com/science/article/pii/S2211124722006593
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    miR-182-5p Regulates Nogo-A Expression and Promotes Neurite Outgrowth of Hippocampal Neurons In Vitro
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    ncbi.nlm.nih.gov/pmc/articles/PMC9146179/
  12. May 2022
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    DDX41 is required for cGAS-STING activation against DNA virus infection
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    sciencedirect.com/science/article/pii/S2211124722006295
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    Aβ oligomer concentration in mouse and human brain and its drug-induced reduction ex vivo
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    sciencedirect.com/science/article/pii/S2666379122001550
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    Glutamate–aspartate transporter 1 attenuates oxygen–glucose deprivation-induced injury by promoting glutamate metabolism in primary cortical neurons
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    onlinelibrary.wiley.com/doi/10.1002/jcp.30768
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    Intracellular infection and immune system cues rewire adipocytes to acquire immune function
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    sciencedirect.com/science/article/pii/S1550413122001358
  17. Apr 2022
  18. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Novel mechanosensory role for acid sensing ion channel subtype 1a in evoking the exercise pressor reflex in rats with heart failure
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    physoc.onlinelibrary.wiley.com/doi/10.1113/JP282923
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    Cellular signals converge at the NOX2-SHP-2 axis to induce reductive carboxylation in cancer cells
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    sciencedirect.com/science/article/pii/S2451945622001271
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    Centrosome-dependent microtubule modifications set the conditions for axon formation
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    sciencedirect.com/science/article/pii/S2211124722004442
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    Lyso-PAF, a biologically inactive phospholipid, contributes to RAF1 activation
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    sciencedirect.com/science/article/pii/S1097276522002647
  22. Nov 2021
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    Prenatal interleukin 6 elevation increases glutamatergic synapse density and disrupts hippocampal connectivity in offspring
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    sciencedirect.com/science/article/pii/S107476132100412X
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    High resistance to Toxoplasma gondii infection in inducible nitric oxide synthase knockout rats
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    sciencedirect.com/science/article/pii/S2589004221012499
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    Enteric glial cell heterogeneity regulates intestinal stem cell niches
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    sciencedirect.com/science/article/pii/S1934590921004161
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Myopalladin knockout mice develop cardiac dilation and show a maladaptive response to mechanical pressure overload
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    ncbi.nlm.nih.gov/pmc/articles/PMC8547954/
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TAZ inhibits glucocorticoid receptor and coordinates hepatic glucose homeostasis in normal physiological states
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    ncbi.nlm.nih.gov/pmc/articles/PMC8555985/
  28. Oct 2021
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mechanistic Insights into COVID-19 by Global Analysis of the SARS-CoV-2 3CLpro Substrate Degradome
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    ncbi.nlm.nih.gov/pmc/articles/PMC8501228/
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    GEM-IL: A highly responsive fluorescent lactate indicator
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    sciencedirect.com/science/article/pii/S2667237521001478
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    Lysosomal Zn2+ release triggers rapid, mitochondria-mediated, non-apoptotic cell death in metastatic melanoma
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    sciencedirect.com/science/article/pii/S2211124721013127
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    A Conserved and Seemingly Redundant Escherichia coli Biotin Biosynthesis Gene Expressed Only During Anaerobic Growth
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    onlinelibrary.wiley.com/doi/10.1111/mmi.14826
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    USP7 and VCPFAF1 define the SUMO/Ubiquitin landscape at the DNA replication fork
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    sciencedirect.com/science/article/pii/S2211124721012833
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    PARP1-mediated PARylation activity is essential for oligodendroglial differentiation and CNS myelination
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    sciencedirect.com/science/article/pii/S2211124721011426
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    AKAP9 supports spermatogenesis through its effects on microtubule and actin cytoskeletons in the rat testis
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202100960R
  36. academic.oup.com academic.oup.com
    HIV-1 establishes a sanctuary site in the testis by permeating the BTB through changes in cytoskeletal organization
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    academic.oup.com/endo/article/162/11/bqab156/6338140
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    Vitamin B12 impacts amyloid beta-induced proteotoxicity by regulating the methionine/S-adenosylmethionine cycle
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    sciencedirect.com/science/article/pii/S2211124721012079
  38. Sep 2021
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Thromboxane A2 receptors contribute to the exaggerated exercise pressor reflex in male rats with heart failure
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    ncbi.nlm.nih.gov/pmc/articles/PMC8461035/
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mesenchymal stem cells attenuate liver fibrosis by targeting Ly6Chi/lo macrophages through activating the cytokine-paracrine and apoptotic pathways
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    ncbi.nlm.nih.gov/pmc/articles/PMC8437974/
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    In vivo CRISPR screens identify the E3 ligase Cop1 as a modulator of macrophage infiltration and cancer immunotherapy target
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    sciencedirect.com/science/article/pii/S0092867421010539
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    Prolyl oligopeptidase inhibition reduces alpha-synuclein aggregation in a cellular model of multiple system atrophy
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    onlinelibrary.wiley.com/doi/10.1111/jcmm.16910
  43. Aug 2021
  44. www.sciencedirect.com www.sciencedirect.com
    The impact of spike N501Y mutation on neutralizing activity and RBD binding of SARS-CoV-2 convalescent serum
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    sciencedirect.com/science/article/pii/S2352396421003376
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  47. www.jneurosci.org www.jneurosci.org
    Inhibition of Prolyl Oligopeptidase Restores Spontaneous Motor Behavior in the α-Synuclein Virus Vector–Based Parkinson's Disease Mouse Model by Decreasing α-Synuclein Oligomeric Species in Mouse Brain
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    jneurosci.org/content/36/49/12485
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modeling Patient-Derived Glioblastoma with Cerebral Organoids
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    ncbi.nlm.nih.gov/pmc/articles/PMC6625753/
  51. www.mdpi.com www.mdpi.com
    Buprenorphine Increases HIV-1 Infection In Vitro but Does Not Reactivate HIV-1 from Latency
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    mdpi.com/1999-4915/13/8/1472
  52. academic.oup.com academic.oup.com
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    academic.oup.com/endo/article/158/6/1798/3064423
  53. onlinelibrary.wiley.com onlinelibrary.wiley.com
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14146
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC5334201/
  55. Jul 2021
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC5659757/
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    An Allosteric Anti-tryptase Antibody for the Treatment of Mast Cell-Mediated Severe Asthma
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    sciencedirect.com/science/article/pii/S0092867419310153
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    Actionable Activating Oncogenic ERBB2/HER2 Transmembrane and Juxtamembrane Domain Mutations
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    sciencedirect.com/science/article/pii/S1535610818304240
  59. www.jbc.org www.jbc.org
    NMDA receptor–dependent dephosphorylation of serine 387 in Argonaute 2 increases its degradation and affects dendritic spine density and maturation
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    jbc.org/content/293/24/9311.long
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    Innate Immune Response and Off-Target Mis-splicing Are Common Morpholino-Induced Side Effects in Xenopus
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    sciencedirect.com/science/article/pii/S1534580718300571
  61. onlinelibrary.wiley.com onlinelibrary.wiley.com
    A Division of labor between two biotin protein ligase homologs
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    onlinelibrary.wiley.com/doi/10.1111/mmi.14761
  62. onlinelibrary.wiley.com onlinelibrary.wiley.com
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    onlinelibrary.wiley.com/doi/full/10.1002/jnr.23602
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    Molecular noise filtering in the β-adrenergic signaling network by phospholamban pentamers
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  64. onlinelibrary.wiley.com onlinelibrary.wiley.com
    NMDA receptor blockade ameliorates abnormalities of spike firing of subthalamic nucleus neurons in a parkinsonian nonhuman primate
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    onlinelibrary.wiley.com/doi/10.1002/jnr.24230
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Validation of commercially available sphingosine kinase 2 antibodies for use in immunoblotting, immunoprecipitation and immunofluorescence
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    ncbi.nlm.nih.gov/pmc/articles/PMC5200942/
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Acute administration of ucf-101 ameliorates the locomotor impairments induced by a traumatic spinal cord injury
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    sciencedirect.com/science/article/pii/S0306452215004789
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    The histone chaperone HIR maintains chromatin states to control nitrogen assimilation and fungal virulence
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    Lysine acetylation restricts mutant IDH2 activity to optimize transformation in AML cells
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  70. Jun 2021
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TRPC1/5-CaV3 Complex Mediates Leptin-Induced Excitability in Hypothalamic Neurons
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    ncbi.nlm.nih.gov/pmc/articles/PMC8226082/
  72. May 2021
  73. www.sciencedirect.com www.sciencedirect.com
    α-Synuclein mutation impairs processing of endomembrane compartments and promotes exocytosis and seeding of α-synuclein pathology
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    sciencedirect.com/science/article/pii/S2211124721004332
  74. www.jneurosci.org www.jneurosci.org
    The Wnt effector TCF7l2 promotes oligodendroglial differentiation by repressing autocrine BMP4-mediated signaling
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    jneurosci.org/content/41/8/1650
  75. www.sciencedirect.com www.sciencedirect.com
    Genetic Characterization of Three Distinct Mechanisms Supporting RNA-Driven DNA Repair and Modification Reveals Major Role of DNA Polymerase ζ
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    A BIN2-GLK1 Signaling Module Integrates Brassinosteroid and Light Signaling to Repress Chloroplast Development in the Dark
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    sciencedirect.com/science/article/pii/S153458072030976X
  77. Apr 2021
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    Di-methylation of CD147-K234 Promotes the Progression of NSCLC by Enhancing Lactate Export
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    sciencedirect.com/science/article/pii/S1550413120306653
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    Leucine-sensing mechanism of leucyl-tRNA synthetase 1 for mTORC1 activation
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    sciencedirect.com/science/article/pii/S2211124721003454
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    Proteostasis Regulators Restore Function of Epilepsy-Associated GABAA Receptors
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    sciencedirect.com/science/article/pii/S2451945620303342
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    Illuminating Host-Mycobacterial Interactions with Genome-wide CRISPR Knockout and CRISPRi Screens
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    sciencedirect.com/science/article/pii/S2405471220302945
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    Phenotypic screen identifies calcineurin-sparing FK506 analogs as BMP potentiators for treatment of acute kidney injury
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    sciencedirect.com/science/article/pii/S2451945621001562
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    Chronic stress physically spares but functionally impairs innate-like invariant T cells
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    Proteolytic Shedding of Human Colony‐Stimulating Factor 1 Receptor and its implication
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    onlinelibrary.wiley.com/doi/full/10.1111/jcmm.16474
  85. Mar 2021
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    Systematic characterization of mutations altering protein degradation in human cancers
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  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Prolyl Oligopeptidase Regulates Dopamine Transporter Oligomerization and Phosphorylation in a PKC- and ERK-Independent Manner
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    ncbi.nlm.nih.gov/pmc/articles/PMC7916783/
  88. Feb 2021
  89. journals.plos.org journals.plos.org
    Harmine inhibits breast cancer cell migration and invasion by inducing the degradation of Twist1
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    journals.plos.org/plosone/article
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Niche-derived soluble DLK1 promotes glioma growth
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  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Limiting RyR2 Open Time Prevents Alzheimer’s Disease-Related Neuronal Hyperactivity and Memory Loss but Not β-Amyloid Accumulation
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    ncbi.nlm.nih.gov/pmc/articles/PMC7532726/
  92. www.cell.com www.cell.com
    Ribosome Collision Is Critical for Quality Control during No-Go Decay
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    cell.com/molecular-cell/abstract/S1097-2765(17)30616-0
  93. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Association of N‐cadherin levels and downstream effectors of Rho GTPases with dendritic spine loss induced by chronic stress in rat hippocampal neurons
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    onlinelibrary.wiley.com/doi/10.1002/jnr.23635
  94. www.cell.com www.cell.com
    Single-cell resolved imaging reveals intra-tumor heterogeneity in glycolysis, transitions between metabolic states, and their regulatory mechanisms
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    cell.com/cell-reports/fulltext/S2211-1247(21)00063-2
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of PARP-7 substrates reveals a role for MARylation in microtubule control in ovarian cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC7884071/
  96. www.jneurosci.org www.jneurosci.org
    High salt intake recruits tonic activation of NR2D subunit-containing extrasynaptic NMDARs in vasopressin neurons
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    jneurosci.org/content/41/6/1145
  97. academic.oup.com academic.oup.com
    KIF15 supports spermatogenesis via its effects on Sertoli cell microtubule, actin, vimentin and septin cytoskeletons
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    academic.oup.com/endo/article/162/4/bqab010/6102572
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    Structure of the catalytic core of the Integrator complex
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  99. Jan 2021
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC7868890/
  101. Dec 2020
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neutrophil infiltration regulates clock-gene expression to organize daily hepatic metabolism
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    ncbi.nlm.nih.gov/pmc/articles/PMC7723411/
  103. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Nanoparticle Vaccines Based on the Receptor Binding Domain (RBD) and Heptad Repeat (HR) of SARS-CoV-2 Elicit Robust Protective Immune Responses
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  104. Nov 2020
  105. www.sciencedirect.com www.sciencedirect.com
    Defining Essential Enhancers for Pluripotent Stem Cells Using a Features-Oriented CRISPR-Cas9 Screen
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