961 Matching Annotations
  1. Sep 2022
  2. www.sciencedirect.com www.sciencedirect.com
    Enteric VIP-producing neurons maintain gut microbiota homeostasis through regulating epithelium fucosylation
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    1. scibot 24 Sep 2022
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    sciencedirect.com/science/article/pii/S1931312822004188
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    cis interaction of CD153 with TCR/CD3 is crucial for the pathogenic activation of senescence-associated T cells
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    1. scibot 21 Sep 2022
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    sciencedirect.com/science/article/pii/S2211124722012050
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    Interaction of RAGE with α-synuclein fibrils mediates inflammatory response of microglia
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    1. scibot 21 Sep 2022
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    sciencedirect.com/science/article/pii/S2211124722012384
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    Spatiotemporal control of ERK pulse frequency coordinates fate decisions during mammary acinar morphogenesis
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    1. scibot 16 Sep 2022
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    sciencedirect.com/science/article/pii/S1534580722005949
  6. journals.plos.org journals.plos.org
    CCT196969 effectively inhibits growth and survival of melanoma brain metastasis cells
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    1. scibot 14 Sep 2022
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      DOI: 10.1371/journal.pone.0273711

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    journals.plos.org/plosone/article
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    PSMG2-controlled proteasome-autophagy balance mediates the tolerance for MEK-targeted therapy in triple-negative breast cancer
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    1. scibot 13 Sep 2022
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    sciencedirect.com/science/article/pii/S2666379122002907
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    Ablating Lgr5-expressing prostatic stromal cells activates the ERK-mediated mechanosensory signaling and disrupts prostate tissue homeostasis
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    1. scibot 08 Sep 2022
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    sciencedirect.com/science/article/pii/S2211124722011378
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    Dopamine drives neuronal excitability via KCNQ channel phosphorylation for reward behavior
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    1. scibot 08 Sep 2022
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    sciencedirect.com/science/article/pii/S2211124722011330
  10. Aug 2022
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    STAT6 in mitochondrial outer membrane impairs mitochondrial fusion by inhibiting MFN2 dimerization
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    1. scibot 30 Aug 2022
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      DOI: 10.1016/j.isci.2022.104923

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    sciencedirect.com/science/article/pii/S2589004222011956
  12. 52.53.155.43 52.53.155.43
    1960-html.html
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  13. aacrjournals.org aacrjournals.org
    Interleukin-27 signaling serves as an immunological checkpoint for innate cytotoxic cells to promote hepatocellular carcinoma
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    1. scibot 27 Aug 2022
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    aacrjournals.org/cancerdiscovery/article/12/8/1960/707258/IL27-Signaling-Serves-as-an-Immunologic-Checkpoint
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    Pituitary adenomas evade apoptosis via noxa deregulation in Cushing’s disease
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    1. scibot 26 Aug 2022
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    sciencedirect.com/science/article/pii/S2211124722010403
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    The AMPK-HOXB9-KRAS axis regulates lung adenocarcinoma growth in response to cellular energy alterations
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    1. scibot 26 Aug 2022
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    sciencedirect.com/science/article/pii/S2211124722010270
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    Internal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade
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    1. scibot 26 Aug 2022
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      DOI: 10.1016/j.medj.2022.07.008

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  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Behavioral and cellular dopamine D1 and D3 receptor-mediated synergy: Implications for L-DOPA-induced dyskinesia
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    1. scibot 26 Aug 2022
      RRID:AB_2281741

      DOI: 10.1016/j.neuropharm.2018.06.024

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    ncbi.nlm.nih.gov/pmc/articles/PMC9380415/
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    Chromatin-bound RB targets promoters, enhancers, and CTCF-bound loci and is redistributed by cell-cycle progression
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    1. scibot 23 Aug 2022
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    sciencedirect.com/science/article/pii/S1097276522007109
  19. www.science.org www.science.org
    Functional and biological heterogeneity of KRASQ61 mutations
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    1. scibot 23 Aug 2022
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      DOI: 10.1126/scisignal.abn2694

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    Tripartite Motif 38 Attenuates Cardiac Fibrosis after Myocardial Infarction by Suppressing TAK1 Activation via TAB2/3 Degradation
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    1. scibot 17 Aug 2022
      RRID:AB_2315112

      DOI: 10.1016/j.isci.2022.104780

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    sciencedirect.com/science/article/pii/S2589004222010525
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    The IRAK4 scaffold integrates TLR4-driven TRIF and MYD88 signaling pathways
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    1. scibot 17 Aug 2022
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    sciencedirect.com/science/article/pii/S2211124722010427
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    Mfsd2b and Spns2 are essential for maintenance of blood vessels during development and in anaphylactic shock
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    1. scibot 17 Aug 2022
      RRID:AB_2315112

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    sciencedirect.com/science/article/pii/S2211124722010257
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    Temporal control of PDGFRα regulates the fibroblast-to-myofibroblast transition in wound healing
    1
    1. scibot 17 Aug 2022
      RRID:AB_2315112

      DOI: 10.1016/j.celrep.2022.111192

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    sciencedirect.com/science/article/pii/S2211124722010099
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    Glycosphingolipids are mediators of cancer plasticity through independent signaling pathways
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    1. scibot 17 Aug 2022
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      DOI: 10.1016/j.celrep.2022.111181

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    sciencedirect.com/science/article/pii/S2211124722009949
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    AP-1 transcription factor network explains diverse patterns of cellular plasticity in melanoma cells
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    1. scibot 10 Aug 2022
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    sciencedirect.com/science/article/pii/S2211124722009561
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    Blocking DCIR mitigates colitis and prevents colorectal tumors by enhancing the GM-CSF-STAT5 pathway
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    sciencedirect.com/science/article/pii/S2211124722009676
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    Inhibition of CSPG receptor PTPσ promotes migration of newly born neuroblasts, axonal sprouting, and recovery from stroke
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    sciencedirect.com/science/article/pii/S2211124722009469
  28. Jul 2022
  29. www.sciencedirect.com www.sciencedirect.com
    High-risk neuroblastoma with NF1 loss of function is targetable using SHP2 inhibition
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  30. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2022 - Li - Maresin 1 intervention Reverses Experimental Pulmonary Arterial Hypertension in mice-html.html
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    52.53.155.43/eeb521b7ce9ed18aede2526ed77220c5d9e406f5/British J Pharmacology - 2022 - Li - Maresin 1 intervention Reverses Experimental Pulmonary Arterial Hypertension in mice-html.html
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    Phosphoproteomics of three exercise modalities identifies canonical signaling and C18ORF25 as an AMPK substrate regulating skeletal muscle function
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    Engineering chimeric antigen receptor neutrophils from human pluripotent stem cells for targeted cancer immunotherapy
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    sciencedirect.com/science/article/pii/S2211124722009342
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    Inactivation of a wheat protein kinase gene confers broad-spectrum resistance to rust fungi
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  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-Wide CRISPR Screening Identifies DCK and CCNL1 as Genes That Contribute to Gemcitabine Resistance in Pancreatic Cancer
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      DOI: 10.3390/cancers14133152

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  35. link.springer.com link.springer.com
    Transmissible ER stress between macrophages and tumor cells configures tumor microenvironment
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      DOI: 10.1007/s00018-022-04413-z

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    A novel germline deletion of p.C630 in RET causes MTC and promotes cell proliferation and sensitivity to pralsetinib
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    academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgac352/6605991
  37. Jun 2022
  38. 52.53.155.43 52.53.155.43
    Control of coronary vascular resistance by eicosanoids via a novel GPCR
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    Bidirectional regulation of synaptic SUMOylation by Group 1 metabotropic glutamate receptors
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    link.springer.com/article/10.1007/s00018-022-04405-z
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    Progesterone limits the tumor-promoting effects of the beta-subunit of human chorionic gonadotropin via non-nuclear receptors
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  41. journals.physiology.org journals.physiology.org
    Control of coronary vascular resistance by eicosanoids via a novel GPCR
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    journals.physiology.org/doi/10.1152/ajpcell.00454.2021
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    The granulosa cell response to luteinizing hormone is partly mediated by YAP1-dependent induction of amphiregulin
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      DOI: 10.1186/s12964-022-00843-1

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    Itaconate is a lysosomal inducer that promotes antibacterial innate immunity
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    Elevated levels of follicular fatty acids induce ovarian inflammation via ERK1/2 and inflammasome activation in PCOS
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      DOI: 10.1210/clinem/dgac281

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  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Astilbin Activates the Reactive Oxidative Species/PPARγ Pathway to Suppress Effector CD4+ T Cell Activities via Direct Binding With Cytochrome P450 1B1
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  47. May 2022
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    Rho–Rho-Kinase Regulates Ras-ERK Signaling Through SynGAP1 for Dendritic Spine Morphology
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    EGFR inhibition potentiates FGFR inhibitor therapy and overcomes resistance in FGFR2 fusion-positive cholangiocarcinoma
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    Cross-species analysis of LZTR1 loss-of-function mutants demonstrates dependency to RIT1 orthologs
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    Downregulation of microRNA-124-3p promotes subventricular zone neural stem cell activation by enhancing the function of BDNF downstream pathways after traumatic brain injury in adult rats
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    Activation of the EGFR/MAPK pathway drives transdifferentiation of quiescent niche cells to stem cells in the Drosophila testis niche
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    Regulation of positive and negative selection and TCR signaling during thymic T cell development by capicua
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    YAP1 and PRDM14 converge to promote cell survival and tumorigenesis
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    A functional taxonomy of tumor suppression in oncogenic KRAS-driven lung cancer
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  93. Dec 2021
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    Translational and post-translational control of human naïve versus primed pluripotency
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    SIRT2 regulates mitochondrial dynamics and reprogramming via MEK1-ERK-DRP1 and AKT1-DRP1 axes
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    Muscarinic signaling regulates voltage-gated potassium channel KCNQ2 phosphorylation in the nucleus accumbens via protein kinase C for aversive learning
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    Endoderm development requires centrioles to restrain p53-mediated apoptosis in the absence of ERK activity
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    Aging Does Not Exacerbate Muscle Loss During Denervation and Lends Unique Muscle-Specific Atrophy Resistance With Akt Activation
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    Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps
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    Inhibition of extracellular vesicle-associated MMP2 abrogates intercellular hepatic miR-122 transfer to liver macrophages and curtails inflammation
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    Halofuginone Sensitizes Lung Cancer Organoids to Cisplatin via Suppressing PI3K/AKT and MAPK Signaling Pathways
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    CHK1 protects oncogenic KRAS-expressing cells from DNA damage and is a target for pancreatic cancer treatment
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    Protein kinase Cι and SRC signaling define reciprocally related subgroups of glioblastoma with distinct therapeutic vulnerabilities
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    Statins affect cancer cell plasticity with distinct consequences for tumor progression and metastasis
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    Parp1 promotes sleep, which enhances DNA repair in neurons
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    Dietary nitrate supplementation prevents radiotherapy-induced xerostomia
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    Role of adipocyte Na,K-ATPase oxidant amplification loop in cognitive decline and neurodegeneration
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    LRG1 destabilizes tumor vessels and restricts immunotherapeutic potency
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    MAPK pathway activation selectively inhibits ASCL1-driven small cell lung cancer
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    Retinoic acid signaling is directly activated in cardiomyocytes and protects mouse hearts from apoptosis after myocardial infarction
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    Anti-Inflammatory and Antimicrobial Volatile Oils: Fennel and Cumin Inhibit Neutrophilic Inflammation via Regulating Calcium and MAPKs
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    Cell geometry, signal dampening, and a bimodal transcriptional response underlie the spatial precision of an ERK-mediated embryonic induction
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    Loss of FBXO31-mediated degradation of DUSP6 dysregulates ERK and PI3K-AKT signaling and promotes prostate tumorigenesis
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    Targeting CDK4/6 Represents a Therapeutic Vulnerability in Acquired BRAF/MEK Inhibitor–Resistant Melanoma
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    PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory
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    Mass Cytometry Reveals Global Immune Remodeling with Multi-lineage Hypersensitivity to Type I Interferon in Down Syndrome
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      Rabbit mAb anti-Phospho- p44/42 MAPK (Thr202/Tyr204) (p-Erk1/2)

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    Midkine promotes articular chondrocyte proliferation through the MK-LRP1-nucleolin signaling pathway
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    ERBB3 overexpression due to miR-205 inactivation confers sensitivity to FGF, metabolic activation, and liability to ERBB3 targeting in glioblastoma
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    OVA66 promotes tumour angiogenesis and progression through enhancing autocrine VEGF-VEGFR2 signalling
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    Critical individual roles of the BCR and FGFR1 kinase domains in BCR‐FGFR1‐driven stem cell leukemia/lymphoma syndrome
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      Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP Rabbit mAb

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    Long chain n-3 fatty acids attenuate oncogenic KRas-driven proliferation by altering plasma membrane nanoscale proteolipid composition
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      Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XPu00a0Rabbit mAb

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    Sustained activation of ERK1/2 MAPK in Schwann cells causes corneal neurofibroma
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