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Apr 2023
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Biphasic expression of thyroid hormone receptor TRβ1 in mammalian retina and anterior ocular tissues

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1. scibot 08 Apr 2023
  
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  AB_2534096
  
  DOI: 10.3389/fendo.2023.1174600
  
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Bub1 and Bub3 regulate metabolic adaptation via macrolipophagy in Drosophila

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1. scibot 08 Apr 2023
  
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  DOI: 10.1016/j.celrep.2023.112343
  
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XLF/Cernunnos loss impairs mouse brain development by altering symmetric proliferative divisions of neural progenitors

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  DOI: 10.1016/j.celrep.2023.112342
  
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sciencedirect.com/science/article/pii/S2211124723003534
Mar 2023
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Examining the engram encoding specificity hypothesis in mice

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1. scibot 29 Mar 2023
  
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  DOI: 10.1016/j.neuron.2023.03.007
  
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Hematopoietic stem cells preferentially traffic misfolded proteins to aggresomes and depend on aggrephagy to maintain protein homeostasis

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1. scibot 28 Mar 2023
  
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  DOI: 10.1016/j.stem.2023.02.010
  
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europepmc.org/article/med/36948186
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Stem cell-based modeling and single-cell multiomics reveal gene-regulatory mechanisms underlying human skeletal development

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  DOI: 10.1016/j.celrep.2023.112276
  
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Multiplex translaminar imaging in the spinal cord of behaving mice

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1. scibot 24 Mar 2023
  
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  DOI: 10.1038/s41467-023-36959-2
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10030868/
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Genetic dissection of mutual interference between two consecutive learning tasks in Drosophila

1
1. scibot 23 Mar 2023
  
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  DOI: 10.7554/eLife.83516
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10030115/
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Inflammasome inhibition protects dopaminergic neurons from α-synuclein pathology in a model of progressive Parkinson’s disease

1
1. scibot 23 Mar 2023
  
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  RRID:AB_253409
  
  DOI: 10.1186/s12974-023-02759-0
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10029189/
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Estradiol regulates leptin sensitivity to control feeding via hypothalamic Cited1

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1. scibot 11 Mar 2023
  
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  DOI: 10.1016/j.cmet.2023.02.004
  
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sciencedirect.com/science/article/pii/S1550413123000402
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Dual role of the P2X7 receptor in dendritic outgrowth during physiological and pathological brain development

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1. scibot 02 Mar 2023
  
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  DOI: 10.1523/JNEUROSCI.0805-22.2022
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9962779/
Feb 2023
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Bat pluripotent stem cells reveal unusual entanglement between host and viruses

1
1. scibot 23 Feb 2023
  
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  DOI: 10.1016/j.cell.2023.01.011
  
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sciencedirect.com/science/article/pii/S0092867423000417
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Inhomogeneous mechanotransduction defines the spatial pattern of apoptosis-induced compensatory proliferation

1
1. scibot 17 Feb 2023
  
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  DOI: 10.1016/j.devcel.2023.01.005
  
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sciencedirect.com/science/article/pii/S1534580723000369
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Caldendrin represses neurite regeneration and growth in dorsal root ganglion neurons

1
1. scibot 17 Feb 2023
  
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  DOI: 10.1038/s41598-023-29622-9
  
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nature.com/articles/s41598-023-29622-9
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3D human induced pluripotent stem cell–derived bioengineered skeletal muscles for tissue, disease and therapy modeling

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1. scibot 17 Feb 2023
  
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  DOI: 10.1038/s41596-022-00790-8
  
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nature.com/articles/s41596-022-00790-8
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Social deprivation induces astrocytic TRPA1-GABA suppression of hippocampal circuits

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1. scibot 16 Feb 2023
  
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  DOI: 10.1016/j.neuron.2023.01.015
  
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The cellular basis of mechanosensation in mammalian tongue

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1. scibot 11 Feb 2023
  
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  DOI: 10.1016/j.celrep.2023.112087
  
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sciencedirect.com/science/article/pii/S2211124723000980
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Senescence Rewires Microenvironment Sensing to Facilitate Antitumor Immunity

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1. scibot 10 Feb 2023
  
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  DOI: 10.1158/2159-8290.CD-22-0528
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9901536/
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Optogenetics and electron tomography for structure-function analysis of cochlear ribbon synapses

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1. scibot 10 Feb 2023
  
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  DOI: 10.7554/eLife.79494
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9908081/
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CD206+ macrophages transventricularly infiltrate the early embryonic cerebral wall to differentiate into microglia

2
1. scibot 09 Feb 2023
  
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  DOI: 10.1016/j.celrep.2023.112092
  
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2. scibot 09 Feb 2023
  
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  RRID:AB_2534096
  
  DOI: 10.1016/j.celrep.2023.112092
  
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The Foundational Data Initiative for Parkinson Disease: Enabling efficient translation from genetic maps to mechanism

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1. scibot 09 Feb 2023
  
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  DOI: 10.1016/j.xgen.2023.100261
  
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A multidimensional atlas of human glioblastoma organoids reveals highly coordinated molecular networks and effective drugs

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  DOI: 10.1101/2023.01.24.525374
  
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biorxiv.org/content/10.1101/2023.01.24.525374v1
Jan 2023
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Mechanism of kisspeptin neuron synchronization for pulsatile hormone secretion in male mice

2
1. scibot 28 Jan 2023
  
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  DOI: 10.1016/j.celrep.2022.111914
  
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2. scibot 04 Jan 2023
  
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  DOI: 10.1016/j.celrep.2022.111914
  
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A dopaminergic reward prediction error signal shapes maternal behavior in mice

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1. scibot 28 Jan 2023
  
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  DOI: 10.1016/j.neuron.2022.11.019
  
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Behavioral state-dependent modulation of insulin-producing cells in Drosophila

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1. scibot 28 Jan 2023
  
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  DOI: 10.1016/j.cub.2022.12.005
  
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Seasonal cues act through the circadian clock and pigment-dispersing factor to control EYES ABSENT and downstream physiological changes

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1. scibot 28 Jan 2023
  
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  DOI: 10.1016/j.cub.2023.01.006
  
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The selective autophagy adaptor p62/SQSTM1 forms phase condensates regulated by HSP27 that facilitate the clearance of damaged lysosomes via lysophagy

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1. scibot 27 Jan 2023
  
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  DOI: 10.1016/j.celrep.2023.112037
  
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Selective integration of diverse taste inputs within a single taste modality

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1. scibot 27 Jan 2023
  
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  DOI: 10.7554/eLife.84856
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9873257/
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Generation of an induced pluripotent stem cell (iPSC) line from a patient with GEFS+ carrying a STX1B (p.Lys45delinsArgMetCysIleGlu and p.Leu46Met) mutation

2
1. scibot 19 Jan 2023
  
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  DOI: 10.1016/j.scr.2023.103028
  
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  DOI: 10.1016/j.scr.2023.103028
  
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sciencedirect.com/science/article/pii/S1873506123000144
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Humidity sensors that alert mosquitoes to nearby hosts and egg-laying sites

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1. scibot 19 Jan 2023
  
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  DOI: 10.1016/j.neuron.2022.12.025
  
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sciencedirect.com/science/article/pii/S0896627322011229
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Neuronopathic GBA1L444P mutation accelerates Glucosylsphingosine levels and formation of hippocampal alpha-synuclein inclusions

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1. scibot 19 Jan 2023
  
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  DOI: 10.1523/JNEUROSCI.0680-22.2022
  
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pmc.ncbi.nlm.nih.gov/articles/PMC9864632/
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Protrusion growth driven by myosin-generated force

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  DOI: 10.1016/j.devcel.2022.12.001
  
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sciencedirect.com/science/article/pii/S1534580722008450
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Neuronal and astrocytic contributions to Huntington’s disease dissected with zinc finger protein transcriptional repressors

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1. scibot 11 Jan 2023
  
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  DOI: 10.1016/j.celrep.2022.111953
  
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Electrical signals in the ER are cell type and stimulus specific with extreme spatial compartmentalization in neurons

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1. scibot 06 Jan 2023
  
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  DOI: 10.1016/j.celrep.2022.111943
  
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sciencedirect.com/science/article/pii/S2211124722018447
Dec 2022
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A novel intergenic enhancer that regulates Bdnf expression in developing cortical neurons

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Foxd1 is Required for 3d Patterning of the Kidney Interstitial Matrix

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Kir4.1 channel activation in NG2 glia contributes to remyelination in ischemic stroke

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Connections between sister and non-sister telomeres of segregating chromatids maintain euploidy

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Structural basis for Parkinson’s disease-linked LRRK2’s binding to microtubules

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The SNARE protein SNAP-25 is required for normal exocytosis at auditory hair cell ribbon synapses

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Developmental trajectories of thalamic progenitors revealed by single-cell transcriptome profiling and Shh perturbation

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B cell expansion hinders the stroma-epithelium regenerative cross talk during mucosal healing

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Table 1 Antibodies and dyes compatible with mLSR-3D

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Physical confinement promotes mesenchymal trans-differentiation of invading transformed cells in vivo

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Intertwined Wdr47-NTD dimer recognizes a basic-helical motif in Camsap proteins for proper central-pair microtubule formation

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Dynamic proteomic and phosphoproteomic atlas of corticostriatal axons in neurodevelopment

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An anti-inflammatory transcriptional cascade conserved from flies to humans

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CASK loss of function differentially regulates neuronal maturation and synaptic function in human induced cortical excitatory neurons

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Sleep need-dependent changes in functional connectivity facilitate transmission of homeostatic sleep drive

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Differential plasticity and fate of brain-resident and recruited macrophages during the onset and resolution of neuroinflammation

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A neurogenetic mechanism of experience-dependent suppression of aggression

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Hypothalamic AgRP neurons exert top-down control on systemic TNF-α release during endotoxemia

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Dopamine activates astrocytes in prefrontal cortex via α1-adrenergic receptors

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Photoreceptors generate neuronal diversity in their target field through a Hedgehog morphogen gradient in Drosophila

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Innate frequency-discrimination hyperacuity in Williams-Beuren syndrome mice

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Regulation of body weight and food intake by AGRP neurons during opioid dependence and abstinence in mice

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A next-generation iPSC-derived forebrain organoid model of tauopathy with tau fibrils by AAV-mediated gene transfer

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Extracellular vesicles mediate the communication of adipose tissue with brain and promote cognitive impairment associated with insulin resistance

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Spatial and temporal control of expression with light-gated LOV-LexA

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Negative autoregulation mitigates collateral RNase activity of repeat-targeting CRISPR-Cas13d in mammalian cells

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osr1 couples intermediate mesoderm cell fate with temporal dynamics of vessel progenitor cell differentiation

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A neural circuit for wind-guided olfactory navigation

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Glial control of sphingolipid levels sculpts diurnal remodeling in a circadian circuit

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In vivo photometry reveals insulin and 2-deoxyglucose maintain prolonged inhibition of VMH Vglut2 neurons in male mice

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Glioblastoma hijacks neuronal mechanisms for brain invasion

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Dendritic Inhibition by Shh Signaling-Dependent Stellate Cell Pool Is Critical for Motor Learning

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IRF8 deficiency induces the transcriptional, functional, and epigenetic reprogramming of cDC1 into the cDC2 lineage

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Neuron-specific translational control shift ensures proteostatic resilience during ER stress

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Functional convergence of on-off direction-selective ganglion cells in the visual thalamus

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Cd59 and inflammation regulate Schwann cell development

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Metabolic-scale gene activation screens identify SLCO2B1 as a heme transporter that enhances cellular iron availability

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Absence of microglia promotes diverse pathologies and early lethality in Alzheimer’s disease mice

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Sodium-calcium exchanger-3 regulates pain “wind-up”: From human psychophysics to spinal mechanisms

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Drosophila gustatory projections are segregated by taste modality and connectivity

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Genetic deletion of the glucocorticoid receptor in Cx3cr1+ myeloid cells is neuroprotective and improves motor recovery after spinal cord injury

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All-viral tracing of monosynaptic inputs to single birthdate-defined neurons in the intact brain

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Stimulation of medial amygdala GABA neurons with kinetically different channelrhodopsins yields opposite behavioral outcomes

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Regionally defined proteomic profiles of human cerebral tissue and organoids reveal conserved molecular modules of neurodevelopment

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An injury-responsive Rac-to-Rho GTPase switch drives activation of muscle stem cells through rapid cytoskeletal remodeling

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Recurrent circadian circuitry regulates central brain activity to maintain sleep

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Canonical Bone Morphogenetic Protein Signaling Regulates Expression of Aquaporin-4 and Its Anchoring Complex in Mouse Astrocytes

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Nasally-delivered interferon-λ protects mice against infection by SARS-CoV-2 variants including Omicron

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CCN2/CTGF—A Modulator of the Optic Nerve Head Astrocyte

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Nup2 meiotic-autonomous region relieves inhibition of Nup60 to promote progression of meiosis and sporulation in Saccharomyces cerevisiae

1
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Drosulfakinin signaling modulates female sexual receptivity in Drosophila

1
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NanoDam identifies Homeobrain (ARX) and Scarecrow (NKX2.1) as conserved temporal factors in the Drosophila central brain and visual system

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Activation of the EGFR/MAPK pathway drives transdifferentiation of quiescent niche cells to stem cells in the Drosophila testis niche

1
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Astrocytic GABA transporter controls sleep by modulating GABAergic signaling in Drosophila circadian neurons

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Identification of bipotent progenitors that give rise to myogenic and connective tissues in mouse

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Transformation of an early-established motor circuit during maturation in zebrafish

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Tonic GABAergic inhibition, via GABAA receptors containing αβƐ subunits, regulates excitability of ventral tegmental area dopamine neurons

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Diurnal rhythms in cholinergic modulation of rapid dopamine signals and associative learning in the striatum

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Hemisynapse Formation Between Target Astrocytes and Cortical Neuron Axons in vitro

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NMDA receptor-dependent prostaglandin-endoperoxide synthase 2 induction in neurons promotes glial proliferation during brain development and injury

1
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Large-scale two-photon calcium imaging in freely moving mice

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Human cerebral organoids reveal progenitor pathology in EML1-linked cortical malformation

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A midbrain-thalamus-cortex circuit reorganizes cortical dynamics to initiate movement

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Visualizing cellular and tissue ultrastructure using Ten-fold Robust Expansion Microscopy (TREx)

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Feb 2022
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Deletion of β-Neurexins in Mice Alters the Distribution of Dense-Core Vesicles in Presynapses of Hippocampal and Cerebellar Neurons

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LAMTOR1 inhibition of TRPML1-dependent lysosomal calcium release regulates dendritic lysosome trafficking and hippocampal neuronal function

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The imprinted Zdbf2 gene finely tunes control of feeding and growth in neonates

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Descending neurons coordinate anterior grooming behavior in Drosophila

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Hypothalamic pregnenolone mediates recognition memory in the context of metabolic disorders

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A cell atlas of microbe-responsive processes in the zebrafish intestine

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Jan 2022
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The lateral posterior clock neurons (LPN) of Drosophila melanogaster express three neuropeptides and have multiple connections within the circadian clock network and beyond

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Serotonergic neurons translate taste detection into internal nutrient regulation

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Trigeminal ganglion and sensory nerves suggest tactile specialization of elephants

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A role for actomyosin contractility in Notch signaling

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Off-Target Expression of Cre-Dependent Adeno-Associated Viruses in Wild-Type C57BL/6J Mice

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Identification and characterization of rostral ventromedial medulla (RVM) neurons synaptically connected to the urinary bladder afferents in female rats with or without neonatal cystitis

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Experimental Epileptogenesis in a Cell Culture Model of Primary Neurons from Rat Brain: A Temporal Multi-Scale Study

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ACE2 and SCARF expression in human DRG nociceptors: implications for SARS-CoV-2 virus neurological effects

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Individual bitter-sensing neurons in Drosophila exhibit both ON and OFF responses that influence synaptic plasticity

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Morphological assessment of GABA and glutamate inputs to GnRH neurons in intact female mice using expansion microscopy

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Brain adiponectin signaling controls peripheral insulin response in Drosophila

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Classification and genetic targeting of cell types in the primary taste and premotor center of the adult Drosophila brain

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Cerebellar spreading depolarization mediates paroxysmal movement disorder

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Reshaping of the androgen-driven chromatin landscape in normal prostate cells by early cancer drivers and effect on therapeutic sensitivity

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Rewiring of human neurodevelopmental gene regulatory programs by human accelerated regions

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Dual role for CXCL12 signaling in semilunar valve development

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Establishment of a GFP::LMNB1 knockin cell line (CSUi002-A-1) from a dystonia patient-specific iPSC by CRISPR/Cas9 editing

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The histone chaperone Anp32e regulates memory formation, transcription, and dendritic morphology by regulating steady-state H2A.Z binding in neurons

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Continuous clonal labeling reveals uniform progenitor potential in the adult exocrine pancreas

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Interaction between Ras and Src clones causes interdependent tumor malignancy via Notch signaling in Drosophila

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Small Interference RNA Targeting Connexin-43 Improves Motor Function and Limits Astrogliosis After Juvenile Traumatic Brain Injury - Aleksandra Ichkova, Andrew M. Fukuda, Nina Nishiyama, Germaine Paris, Andre Obenaus, Jerome Badaut, 2019

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Alcohol Consumption during Adolescence in a Mouse Model of Binge Drinking Alters the Intrinsic Excitability and Function of the Prefrontal Cortex through a Reduction in the Hyperpolarization-Activated Cation Current

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Untitled document

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Upregulation of Anandamide Hydrolysis in the Basolateral Complex of Amygdala Reduces Fear Memory Expression and Indices of Stress and Anxiety

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Extended Flight Bouts Require Disinhibition from GABAergic Mushroom Body Neurons

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Modeling Patient-Derived Glioblastoma with Cerebral Organoids

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A neuronal mechanism controlling the choice between feeding and sexual behaviors in Drosophila

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Ablation of neuronal ADAM17 impairs oligodendrocyte differentiation and myelination

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Inhibitory Connectivity Dominates the Fan Cell Network in Layer II of Lateral Entorhinal Cortex

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Overlapping morphological and functional properties between M4 and M5 intrinsically photosensitive retinal ganglion cells

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Fast Serotonin Voltammetry as a Versatile Tool for Mapping Dynamic Tissue Architecture: I. Responses at Carbon Fibers Describe Local Tissue Physiology

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Upregulation of Anandamide Hydrolysis in the Basolateral Complex of Amygdala Reduces Fear Memory Expression and Indices of Stress and Anxiety

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High-potency ligands for DREADD imaging and activation in rodents and monkeys

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A toolbox of nanobodies developed and validated for use as intrabodies and nanoscale immunolabels in brain neurons

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Gene Co-expression Analysis Identifies Histone Deacetylase 5 and 9 Expression in Midbrain Dopamine Neurons and as Regulators of Neurite Growth via Bone Morphogenetic Protein Signaling

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Urothelial organoids originating from Cd49f high mouse stem cells display Notch-dependent differentiation capacity

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α-Ketoglutarate links p53 to cell fate during tumour suppression

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Role of the Astroglial Glutamate Exchanger xCT in Ventral Hippocampus in Resilience to Stress

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Precise in vivo genome editing via single homology arm donor mediated intron-targeting gene integration for genetic disease correction

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Imaging neuropeptide release at synapses with a genetically engineered reporter

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  Alexa Fluor 488 Goat anti-Chicken IgY
  
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Local synaptic inputs support opposing, network-specific odor representations in a widely projecting modulatory neuron

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Persistent Sodium Current Drives Excitability of Immature Renshaw Cells in Early Embryonic Spinal Networks

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Synapse maintenance and restoration in the retina by NGL2

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Gad1‐promotor‐driven GFP expression in non‐GABAergic neurons of the nucleus endopiriformis in a transgenic mouse line

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Matriptase activation of Gq drives epithelial disruption and inflammation via RSK and DUOX

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Perturbed DNA methylation by Gadd45b induces chromatin disorganization, DNA strand breaks and dopaminergic neuron death

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Sustained treatment with an α5 GABA A receptor negative allosteric modulator delays excitatory circuit development while maintaining GABAergic neurotransmission

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Hypothalamic control of interoceptive hunger

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The Wnt/PCP formin Daam1 drives cell-cell adhesion during nephron development

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Dysregulation of GABAA Receptor-Mediated Neurotransmission during the Auditory Cortex Critical Period in the Fragile X Syndrome Mouse Model

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Anterior thalamic dysfunction underlies cognitive deficits in a subset of neuropsychiatric disease models

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Danger perception and stress response through an olfactory sensor for the bacterial metabolite hydrogen sulfide

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Vinculin-mediated axon growth requires interaction with actin but not talin in mouse neocortical neurons

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Protein appetite drives macronutrient-related differences in ventral tegmental area neural activity

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Specific and behaviorally consequential astrocyte Gq GPCR signaling attenuation in vivo with iβARK

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Generation of interspecies mouse-rat chimeric embryos by embryonic stem (ES) cell microinjection

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Preoptic BRS3 neurons increase body temperature and heart rate via multiple pathways

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NDNF interneurons in layer 1 gain-modulate whole cortical columns according to an animal’s behavioral state

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Convergence of peptidergic and non-peptidergic protein markers in the human dorsal root ganglion and spinal dorsal horn

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Rab34 GTPase mediates ciliary membrane formation in the intracellular ciliogenesis pathway

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CX3CR1 mutation alters synaptic and astrocytic protein expression, topographic gradients, and response latencies in the auditory brainstem

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  DOI: 10.1002/cne.25150
  
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A Hierarchy of Proliferative and Migratory Keratinocytes Maintains the Tympanic Membrane

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1. scibot 09 May 2021
  
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  DOI: 10.1016/j.stem.2020.10.006
  
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Generation of Functional Organs Using a Cell-Competitive Niche in Intra- and Inter-species Rodent Chimeras

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  DOI: 10.1016/j.stem.2020.11.019
  
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Context-Specific Striatal Astrocyte Molecular Responses Are Phenotypically Exploitable

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  DOI: 10.1016/j.neuron.2020.09.021
  
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Parallel Social Information Processing Circuits Are Differentially Impacted in Autism

1
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  DOI: 10.1016/j.neuron.2020.10.002
  
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Remotely Produced and Axon-Derived Netrin-1 Instructs GABAergic Neuron Migration and Dopaminergic Substantia Nigra Development

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  DOI: 10.1016/j.neuron.2020.05.037
  
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A Neural Network for Wind-Guided Compass Navigation

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1. scibot 08 May 2021
  
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  DOI: 10.1016/j.neuron.2020.06.022
  
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Developmental Attenuation of Neuronal Apoptosis by Neural-Specific Splicing of Bak1 Microexon

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  DOI: 10.1016/j.neuron.2020.06.036
  
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Functional Interplay between Histone H2B ADP-Ribosylation and Phosphorylation Controls Adipogenesis

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  DOI: 10.1016/j.molcel.2020.08.002
  
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The Scf/Kit pathway implements self-organized epithelial patterning

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  DOI: 10.1016/j.devcel.2021.02.026
  
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DNA Damage Promotes Epithelial Hyperplasia and Fate Mis-specification via Fibroblast Inflammasome Activation

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  DOI: 10.1016/j.devcel.2020.09.021
  
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Apr 2021
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Defined p16High Senescent Cell Types Are Indispensable for Mouse Healthspan

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  DOI: 10.1016/j.cmet.2020.05.002
  
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Semaphorin3F Drives Dendritic Spine Pruning Through Rho-GTPase Signaling

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1. scibot 26 Apr 2021
  
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  DOI: 10.1007/s12035-021-02373-2
  
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Single-Cell Transcriptomics Reveals Early Emergence of Liver Parenchymal and Non-parenchymal Cell Lineages

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  DOI: 10.1016/j.cell.2020.09.012
  
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Local projections of layer Vb-to-Va are more prominent in lateral than in medial entorhinal cortex

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  DOI: 10.7554/eLife.67262
  
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A visual pathway for skylight polarization processing in Drosophila

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  DOI: 10.7554/eLife.63225
  
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CD81 Controls Beige Fat Progenitor Cell Growth and Energy Balance via FAK Signaling

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  DOI: 10.1016/j.cell.2020.06.021
  
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Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis

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  DOI: 10.1016/j.ccell.2021.02.016
  
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Chemogenetic manipulation of astrocytic signaling in the basolateral amygdala reduces binge‐like alcohol consumption in male mice

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  DOI: 10.1002/jnr.24841
  
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Betaine ameliorates schizophrenic traits by functionally compensating for KIF3-based CRMP2 transport

1
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  DOI: 10.1016/j.celrep.2021.108971
  
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Mar 2021
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Optic nerve regeneration screen identifies multiple genes restricting adult neural repair

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  DOI: 10.1016/j.celrep.2021.108777
  
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