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651 Matching Annotations

Jul 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

AhR ligand aminoflavone suppresses α6‐integrin–Src–Akt signaling to attenuate tamoxifen resistance in breast cancer cells

1
1. scibot 27 Jul 2021
  
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  RRID:AB_32928
  
  DOI: 10.1002/jcp.27013
  
  Resource: (Cell Signaling Technology Cat# 9271, RRID:AB_329825)
  
  Curator: @Naa003
  
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  Curator comments: Phospho-Akt (Ser473) Antibody Cell Signaling Technology Cat# 9271 also 9271S, 9271L, NYUIHC-310
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6202151/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 27 Jul 2021
  
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  AB_329825
  
  DOI: 10.1210/en.2017-00738
  
  Resource: (Cell Signaling Technology Cat# 9271, RRID:AB_329825)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6283434/
europepmc.org europepmc.org

A Novel Small Molecule GDNF Receptor RET Agonist, BT13, Promotes Neurite Growth from Sensory Neurons in Vitro and Attenuates Experimental Neuropathy in the Rat.

1
1. scibot 27 Jul 2021
  
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  RRID:AB_329826
  
  DOI: 10.3389/fphar.2017.00365
  
  Resource: (Cell Signaling Technology Cat# 9271, RRID:AB_329825)
  
  Curator: @bandrow
  
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  RRID:AB_329825 RRIDCUR:Unresolved
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europepmc.org/articles/PMC5478727/
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Modulation of Akt vs Stat3 activity by the focal adhesion kinase in non-neoplastic mouse fibroblasts

1
1. scibot 15 Jul 2021
  
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  Cell-signalling technology Cat. #9271
  
  DOI: 10.1016/j.yexcr.2021.112731
  
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sciencedirect.com/science/article/pii/S0014482721002639
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Extracellular domain shedding of the ALK receptor mediates neuroblastoma cell migration

1
1. scibot 14 Jul 2021
  
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  RRID:AB_329825
  
  DOI: 10.1016/j.celrep.2021.109363
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8328392/
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Doxorubicin induces dysregulation of AMPA receptor and impairs hippocampal synaptic plasticity leading to learning and memory deficits

1
1. scibot 02 Jul 2021
  
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  AB_329825
  
  DOI: 10.1016/j.heliyon.2021.e07456
  
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sciencedirect.com/science/article/pii/S2405844021015590
Jun 2021
journals.physiology.org journals.physiology.org

Pancreatic fat cells of humans with type 2 diabetes display reduced adipogenic and lipolytic activity | American Journal of Physiology-Cell Physiology

1
1. scibot 29 Jun 2021
  
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  RRID:AB_329825
  
  DOI: 10.1152/ajpcell.00595.2020
  
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journals.physiology.org/doi/full/10.1152/ajpcell.00595.2020
academic.oup.com academic.oup.com

Endothelial insulin receptors promote VEGF-A signaling via ERK1/2 and sprouting angiogenesis

1
1. scibot 29 Jun 2021
  
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  RRID:AB_329825
  
  DOI: 10.1210/endocr/bqab104
  
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academic.oup.com/endo/article/162/8/bqab104/6284300
academic.oup.com academic.oup.com

CX3CL1–CX3CR1 signalling deficiency exacerbates obesity-induced inflammation and insulin resistance in male mice

1
1. scibot 29 Jun 2021
  
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  RRID:AB_329825
  
  DOI: 10.1210/endocr/bqab064
  
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academic.oup.com/endo/article/162/6/bqab064/6188411
journals.physiology.org journals.physiology.org

Pancreatic fat cells of humans with type 2 diabetes display reduced adipogenic and lipolytic activity

1
1. scibot 29 Jun 2021
  
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  RRID:AB_329825
  
  DOI: 10.1152/ajpcell.00595.2020
  
  Resource: (Cell Signaling Technology Cat# 9271, RRID:AB_329825)
  
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journals.physiology.org/doi/abs/10.1152/ajpcell.00595.2020
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Co-occurring gain-of-function mutations in HER2 and HER3 modulate HER2/HER3 activation, oncogenesis, and HER2 inhibitor sensitivity

1
1. scibot 25 Jun 2021
  
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  RRID:AB_329825
  
  DOI: 10.1016/j.ccell.2021.06.001
  
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sciencedirect.com/science/article/pii/S1535610821002841
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The AML microenvironment catalyzes a stepwise evolution to gilteritinib resistance

1
1. scibot 25 Jun 2021
  
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  RRID:AB_329825
  
  DOI: 10.1016/j.ccell.2021.06.003
  
  Resource: (Cell Signaling Technology Cat# 9271, RRID:AB_329825)
  
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sciencedirect.com/science/article/pii/S1535610821002865
www.frontiersin.org www.frontiersin.org

Promotion of Bone Lesions Through the Myeloma Integrin α6-Mediated Osteolytic Signaling

1
1. scibot 19 Jun 2021
  
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  AB_329825
  
  DOI: 10.3389/fonc.2021.692190
  
  Resource: (Cell Signaling Technology Cat# 9271, RRID:AB_329825)
  
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frontiersin.org/article/10.3389/fonc.2021.692190/full
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Glutamine regulates ovarian cancer cell migration and invasion through ETS1

1
1. scibot 17 Jun 2021
  
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  RRID:AB_329825
  
  DOI: 10.1016/j.heliyon.2021.e07064
  
  Resource: (Cell Signaling Technology Cat# 9271, RRID:AB_329825)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8180613/
faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com

Palmitic acid induces insulin resistance by a mechanism associated with energy metabolism and calcium entry in neuronal cells

1
1. scibot 17 Jun 2021
  
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  RRID:AB_329825
  
  DOI: 10.1096/fj.202100243R
  
  Resource: (Cell Signaling Technology Cat# 9271, RRID:AB_329825)
  
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faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202100243R
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The CD44/COL17A1 pathway promotes the formation of multilayered, transformed epithelia

1
1. scibot 04 Jun 2021
  
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  RRID:AB_329825
  
  DOI: 10.1016/j.cub.2021.04.078
  
  Resource: (Cell Signaling Technology Cat# 9271, RRID:AB_329825)
  
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sciencedirect.com/science/article/pii/S0960982221006254
May 2021
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PD-L1 recruits phospholipase C and enhances tumorigenicity of lung tumors harboring mutant forms of EGFR

1
1. scibot 26 May 2021
  
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  RRID:AB_329825
  
  DOI: 10.1016/j.celrep.2021.109181
  
  Resource: (Cell Signaling Technology Cat# 9271, RRID:AB_329825)
  
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sciencedirect.com/science/article/pii/S221112472100526X
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The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer

1
1. scibot 18 May 2021
  
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  RRID:AB_329825
  
  DOI: 10.1016/j.cell.2021.04.022
  
  Resource: (Cell Signaling Technology Cat# 9271, RRID:AB_329825)
  
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sciencedirect.com/science/article/pii/S009286742100502X
cancerres.aacrjournals.org cancerres.aacrjournals.org

Integrated Screens Identify CDK1 as a Therapeutic Target in Advanced Gastrointestinal Stromal Tumors

1
1. scibot 13 May 2021
  
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  RRID:AB_329825
  
  DOI: 10.1158/0008-5472.CAN-20-3580
  
  Resource: (Cell Signaling Technology Cat# 9271, RRID:AB_329825)
  
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cancerres.aacrjournals.org/content/81/9/2481
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The selective lipoprotein-associated phospholipase A2 inhibitor darapladib triggers irreversible actions on glioma cell apoptosis and mitochondrial dysfunction

1
1. scibot 09 May 2021
  
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  RRID:AB_329825
  
  DOI: 10.1016/j.taap.2020.115133
  
  Resource: (Cell Signaling Technology Cat# 9271, RRID:AB_329825)
  
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sciencedirect.com/science/article/pii/S0041008X20302593
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Pathologic HIF1α signaling drives adipose progenitor dysfunction in obesity

1
1. scibot 09 May 2021
  
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  RRID:AB_329825
  
  DOI: 10.1016/j.stem.2020.12.008
  
  Resource: (Cell Signaling Technology Cat# 9271, RRID:AB_329825)
  
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sciencedirect.com/science/article/pii/S1934590920305920
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DNA Damage Promotes TMPRSS2-ERG Oncoprotein Destruction and Prostate Cancer Suppression via Signaling Converged by GSK3β and WEE1

1
1. scibot 07 May 2021
  
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  RRID:AB_329825
  
  DOI: 10.1016/j.molcel.2020.07.028
  
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sciencedirect.com/science/article/pii/S1097276520305190
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Insulin- and Lipopolysaccharide-Mediated Signaling in Adipose Tissue Macrophages Regulates Postprandial Glycemia through Akt-mTOR Activation

1
1. scibot 07 May 2021
  
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  RRID:AB_329825
  
  DOI: 10.1016/j.molcel.2020.04.033
  
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sciencedirect.com/science/article/pii/S1097276520302756
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HectD1 controls hematopoietic stem cell regeneration by coordinating ribosome assembly and protein synthesis

1
1. scibot 07 May 2021
  
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  RRID:AB_32982
  
  DOI: 10.1016/j.stem.2021.02.008
  
  Resource: (Cell Signaling Technology Cat# 9271, RRID:AB_329825)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_329825
  
  Curator comments: Phospho-Akt (Ser473) Antibody Cell Signaling Technology Cat# 9271
  
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  RRIDCUR:Unresolved RRID:AB_329825 RRIDCUR:Incorrect
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sciencedirect.com/science/article/pii/S1934590921000588
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Small Extracellular Vesicle Regulation of Mitochondrial Dynamics Reprograms a Hypoxic Tumor Microenvironment

1
1. scibot 05 May 2021
  
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  RRID:AB_329825
  
  DOI: 10.1016/j.devcel.2020.07.014
  
  Resource: (Cell Signaling Technology Cat# 9271, RRID:AB_329825)
  
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sciencedirect.com/science/article/pii/S1534580720305888
Apr 2021
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Caloric Restriction Promotes Immunometabolic Reprogramming Leading to Protection from Tuberculosis

1
1. scibot 30 Apr 2021
  
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  RRID:AB_329825
  
  DOI: 10.1016/j.cmet.2020.12.016
  
  Resource: (Cell Signaling Technology Cat# 9271, RRID:AB_329825)
  
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sciencedirect.com/science/article/pii/S1550413120306719
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MiR-690, an exosomal-derived miRNA from M2-polarized macrophages, improves insulin sensitivity in obese mice

1
1. scibot 30 Apr 2021
  
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  RRID:AB_329825
  
  DOI: 10.1016/j.cmet.2020.12.019
  
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sciencedirect.com/science/article/pii/S1550413120307178
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Functional Genomics Identifies Metabolic Vulnerabilities in Pancreatic Cancer

1
1. scibot 29 Apr 2021
  
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  RRID:AB_329825
  
  DOI: 10.1016/j.cmet.2020.10.018
  
  Resource: (Cell Signaling Technology Cat# 9271, RRID:AB_329825)
  
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sciencedirect.com/science/article/pii/S1550413120305519
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Central Ceramide Signaling Mediates Obesity-Induced Precocious Puberty

1
1. scibot 29 Apr 2021
  
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  RRID:AB_329825
  
  DOI: 10.1016/j.cmet.2020.10.001
  
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sciencedirect.com/science/article/pii/S1550413120305349
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Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle

1
1. scibot 29 Apr 2021
  
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  RRID:AB_329825
  
  DOI: 10.1016/j.cmet.2020.08.011
  
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sciencedirect.com/science/article/pii/S1550413120304241
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Combined Omics Approaches Reveal the Roles of Non-canonical WNT7B Signaling and YY1 in the Proliferation of Human Pancreatic Progenitor Cells

1
1. scibot 27 Apr 2021
  
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  RRID:AB_329825
  
  DOI: 10.1016/j.chembiol.2020.08.018
  
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sciencedirect.com/science/article/pii/S2451945620303408
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Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis

1
1. scibot 22 Apr 2021
  
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  RRID:AB_329825
  
  DOI: 10.1016/j.ccell.2021.02.016
  
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sciencedirect.com/science/article/pii/S1535610821001185
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Reduced Mitochondrial Apoptotic Priming Drives Resistance to BH3 Mimetics in Acute Myeloid Leukemia

1
1. scibot 22 Apr 2021
  
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  RRID:AB_329825
  
  DOI: 10.1016/j.ccell.2020.10.010
  
  Resource: (Cell Signaling Technology Cat# 9271, RRID:AB_329825)
  
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  SciCrunch record: RRID:AB_329825
  
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  RRIDCUR:Validated RRID:AB_329825
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sciencedirect.com/science/article/pii/S1535610820305419
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Developmental partitioning of SYK and ZAP70 prevents autoimmunity and cancer

1
1. scibot 20 Apr 2021
  
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  RRID:AB_329825
  
  DOI: 10.1016/j.molcel.2021.03.043
  
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  RRID:AB_329825 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1097276521002641
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Gene editing and synthetically accessible inhibitors reveal role for TPC2 in HCC cell proliferation and tumor growth

1
1. scibot 11 Apr 2021
  
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  RRID:AB_329825
  
  DOI: 10.1016/j.chembiol.2021.01.023
  
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Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) Interacts With Colony-Stimulating Factor 1 Receptor (CSF1R) but Is Not Necessary for CSF1/CSF1R-Mediated Microglial Survival

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Hericium erinaceus mycelium and its small bioactive compounds promote oligodendrocyte maturation with an increase in myelin basic protein

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Transcriptional programming drives Ibrutinib-resistance evolution in mantle cell lymphoma

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BPS Publications

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  DOI: 10.1111/bph.15368
  
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CXCR4 signaling at the fetal-maternal interface may drive inflammation and syncytia formation during ovine pregnancy †

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An Embryonic Diapause-like Adaptation with Suppressed Myc Activity Enables Tumor Treatment Persistence

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Alternative signaling pathways from IGF1 or Insulin to Akt activation and Foxo1 nuclear efflux in adult skeletal muscle fibers

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  phospho-AKT Ser473
  
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Selective targeting of the androgen receptor-DNA binding domain by the novel antiandrogen SBF-1 and inhibition of the growth of prostate cancer cells

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PD-L1 Reverse Signaling in Dermal Dendritic Cells Promotes Dendritic Cell Migration Required for Skin Immunity

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The insulin‐sensitizing effect of a single exercise bout is similar in type I and type II human muscle fibres

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ErbB3 is a critical regulator of cytoskeletal dynamics in brain microvascular endothelial cells: Implications for vascular remodeling and blood-brain-barrier modulation - Limin Wu, Mohammad R Islam, Janice Lee, Hajime Takase, Shuzhen Guo, Allison M Andrews, Tetyana P Buzhdygan, Justin Mathew, Wenlu Li, Ken Arai, Eng H Lo, Servio H Ramirez, Josephine Lok, 2021

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Mitochondrial Threonyl-tRNA Synthetase TARS2 Is Required for Threonine-Sensitive mTORC1 Activation

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Inflammation-driven senescence-associated secretory phenotype in cancer-associated fibroblasts enhances peritoneal dissemination

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LncRNA RP6‐65G23.1 accelerates proliferation and inhibits apoptosis via p‐ERK1/2/p‐AKT signaling pathway on keratinocytes

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onlinelibrary.wiley.com/doi/10.1002/jcb.29685
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Reduced Na+K+‐ATPase activity may reduce amino acid uptake in IUGR fetal sheep muscle despite unchanged ex vivo amino acid transporter activity

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Synergistic growth inhibition mediated by dual PI3K/mTOR pathway targeting and genetic or direct pharmacological AKT inhibition in human glioblastoma models

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onlinelibrary.wiley.com/doi/10.1111/jnc.14899
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Insulin‐stimulated glucose uptake partly relies on p21‐activated kinase 2 (PAK2), but not PAK1, in mouse skeletal muscle

1
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  AB_329
  
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An acetyl-histone vulnerability in PI3K/AKT inhibition-resistant cancers is targetable by both BET and HDAC inhibitors

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ARHGEF3 regulates skeletal muscle regeneration and strength through autophagy

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A feed-forward regulatory loop in adipose tissue promotes signaling by the hepatokine FGF21

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ARHGEF3 Regulates Skeletal Muscle Regeneration and Strength through Autophagy

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Autoimmune activation of the GnRH receptor induces insulin resistance independent of obesity in a female rat model

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physoc.onlinelibrary.wiley.com/doi/10.14814/phy2.14672
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Staphylococcus aureus Panton‐Valentine Leukocidin triggers an alternative NETosis process targeting mitochondria

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Hetero-oligomerization of Rho and Ras GTPases Connects GPCR Activation to mTORC2-AKT Signaling

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TSPAN1: A Novel Protein Involved in Head and Neck Squamous Cell Carcinoma Chemoresistance

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Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling in KMT2D Mutant Melanoma

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A Small-Molecule Approach to Restore a Slow-Oxidative Phenotype and Defective CaMKIIβ Signaling in Limb Girdle Muscular Dystrophy

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Phosphorylation of eIF2α promotes Schwann cell differentiation and myelination in CMT1B mice with activated UPR

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jneurosci.org/content/40/42/8174
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Mechanisms by which membrane and nuclear ER alpha inhibit adipogenesis in cells isolated from female mice

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TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment

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MED19 Regulates Adipogenesis and Maintenance of White Adipose Tissue Mass by Mediating PPARγ-Dependent Gene Expression

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Maternal exercise attenuates the lower skeletal muscle glucose uptake and insulin secretion caused by paternal obesity in female adult rat offspring

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Metabolic Imaging Detects Resistance to PI3Kα Inhibition Mediated by Persistent FOXM1 Expression in ER+ Breast Cancer

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HSP90 Inhibitor, 17-DMAG, Alone and in Combination with Lapatinib Attenuates Acquired Lapatinib-Resistance in ER-positive, HER2-Overexpressing Breast Cancer Cell Line

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A Single Bout of One-legged Exercise to Local Exhaustion Decreases Insulin Action in Non-exercised Muscle Leading to Decreased Whole-body Insulin Action

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Enhanced Akt/GSK‐3β/CREB signaling mediates the anti‐inflammatory actions of mGluR5 positive allosteric modulators in microglia and following traumatic brain injury in male mice

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Enhancer-Driven lncRNA BDNF-AS Induces Endocrine Resistance and Malignant Progression of Breast Cancer through the RNH1/TRIM21/mTOR Cascade

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Metabolic Control over mTOR-Dependent Diapause-like State

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Pharmacological targeting of α3β4 nicotinic receptors improves peripheral insulin sensitivity in mice with diet-induced obesity

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Nutrient-Driven O-GlcNAcylation Controls DNA Damage Repair Signaling and Stem/Progenitor Cell Homeostasis

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Dissociation of Adaptive Thermogenesis from Glucose Homeostasis in Microbiome-Deficient Mice

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High‐frequency transcranial magnetic stimulation protects APP/PS1 mice against Alzheimer’s disease progress by reducing APOE and enhancing autophagy

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Streptococcus pneumoniae Infection Promotes Histone H3 Dephosphorylation by Modulating Host PP1 Phosphatase

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Formation of Human Neuroblastoma in Mouse-Human Neural Crest Chimeras

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The endothelial barrier is not rate-limiting to insulin action in the myocardium of male mice

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Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone

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Analysis of pulsed cisplatin signalling dynamics identifies effectors of resistance in lung adenocarcinoma

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Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers

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Differential Signaling Mediated by ApoE2, ApoE3, and ApoE4 in Human Neurons Parallels Alzheimer's Disease Risk

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Topological Adaptation of Transmembrane Domains to the Force-Modulated Lipid Bilayer Is a Basis of Sensing Mechanical Force

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Cancer causes metabolic perturbations associated with reduced insulin-stimulated glucose uptake in peripheral tissues and impaired muscle microvascular perfusion

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Late Endosomes Act as mRNA Translation Platforms and Sustain Mitochondria in Axons

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Effects of acute aerobic, resistance and combined exercises on 24-h glucose variability and skeletal muscle signalling responses in type 1 diabetics

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Synthesis, biological evaluation and toxicity of novel tetrandrine analogues

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Acute pharmacological inhibition of matrix metalloproteinase‐9 activity during development restores perineuronal net formation and normalizes auditory processing in Fmr1 KO mice

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DPP-4 inhibition with anagliptin reduces lipotoxicity-induced insulin resistance and steatohepatitis in male mice

1
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Tau Reduction Prevents Key Features of Autism in Mouse Models

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Translational Physiology: Insulin signaling displayed a differential tissue-specific response to low-dose dihydrotestosterone in female mice

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Evidence That STK19 Is Not an NRAS-dependent Melanoma Driver

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Protein synthesis inhibition promotes nitric oxide generation and activation of CGKII-dependent downstream signaling pathways in the retina

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Three-dimensional growth of breast cancer cells potentiates the anti-tumor effects of unacylated ghrelin and AZP-531

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Hyperactivation of TORC1 Drives Resistance to the Pan-HER Tyrosine Kinase Inhibitor Neratinib in HER2-Mutant Cancers

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Developmental and Tumor Angiogenesis Requires the Mitochondria-Shaping Protein Opa1

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Microphthalmia transcription factor expression contributes to bone marrow failure in Fanconi anemia

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BPS Publications

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β2‐adrenoceptor activation improves skeletal muscle autophagy in neurogenic myopathy

1
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AMPK-Regulated Astrocytic Lactate Shuttle Plays a Non-Cell-Autonomous Role in Neuronal Survival

1
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Diet Intake Control Is Indispensable for the Gluconeogenic Response to Sodium‐Glucose Cotransporter 2 Inhibition in Male Mice

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  anti‐phospho‐Akt
  
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Estrogen Stimulation of Pleiotrophin Enhances Osteoblast Differentiation and Maintains Bone Mass in IGFBP-2 Null Mice

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Cathepsin B inhibition blocks neurite outgrowth in cultured neurons by regulating lysosomal trafficking and remodeling

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Obesity-linked suppression of membrane-bound O-acyltransferase 7 (MBOAT7) drives non-alcoholic fatty liver disease

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Enhanced mGlu5 Signaling in Excitatory Neurons Promotes Rapid Antidepressant Effects via AMPA Receptor Activation

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  DOI: 10.1016/j.neuron.2019.07.011
  
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Divergent Polypharmacology-Driven Cellular Activity of Structurally Similar Multi-Kinase Inhibitors through Cumulative Effects on Individual Targets

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A novel 2‐aminobenzimidazole‐based compound Jzu 17 exhibits anti‐ angiogenesis effects via targeting VEGFR‐2 signaling

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  DOI: 10.1111/bph.14813
  
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Acyl-CoA-Binding Protein Is a Lipogenic Factor that Triggers Food Intake and Obesity

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VE-Cadherin Is Required for Lymphatic Valve Formation and Maintenance

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Combination of Hypoglycemia and Metformin Impairs Tumor Metabolic Plasticity and Growth by Modulating the PP2A-GSK3β-MCL-1 Axis

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High-endothelial cell-derived S1P regulates dendritic cell localization and vascular integrity in the lymph node

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PAK4 Kinase Activity Plays a Crucial Role in the Podosome Ring of Myeloid Cells

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Molecularly Distinct Clathrin-Coated Pits Differentially Impact EGFR Fate and Signaling

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DIRAS3 (ARHI) Blocks RAS/MAPK Signaling by Binding Directly to RAS and Disrupting RAS Clusters

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Deletion of Fmr1 from Forebrain Excitatory Neurons Triggers Abnormal Cellular, EEG, and Behavioral Phenotypes in the Auditory Cortex of a Mouse Model of Fragile X Syndrome

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Gestational intermittent hypoxia induces endothelial dysfunction, reduces perivascular adiponectin and causes epigenetic changes in adult male offspring

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Myc‐dependent endothelial proliferation is controlled by phosphotyrosine 1212 in VEGF receptor‐2

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CRH Promotes the Neurogenic Activity of Neural Stem Cells in the Adult Hippocampus

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Hepatic nitric oxide synthase 1 adaptor protein regulates glucose homeostasis and hepatic insulin sensitivity in obese mice depending on its PDZ binding domain

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GPD1 Specifically Marks Dormant Glioma Stem Cells with a Distinct Metabolic Profile

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α-Ketoglutarate-Activated NF-κB Signaling Promotes Compensatory Glucose Uptake and Brain Tumor Development

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Small-Molecule and CRISPR Screening Converge to Reveal Receptor Tyrosine Kinase Dependencies in Pediatric Rhabdoid Tumors

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Paradigms for Precision Medicine in Epichaperome Cancer Therapy

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Lipid Deprivation Induces a Stable, Naive-to-Primed Intermediate State of Pluripotency in Human PSCs

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Endogenous IGF Signaling Directs Heterogeneous Mesoderm Differentiation in Human Embryonic Stem Cells

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A Breakdown in Metabolic Reprogramming Causes Microglia Dysfunction in Alzheimer's Disease

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mTORC1 Activation Requires DRAM-1 by Facilitating Lysosomal Amino Acid Efflux

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Role of hepatic glucocorticoid receptor in metabolism in models of 5αR1 Deficiency in Male Mice

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Perioperative infusion of glucagon like peptide-1 prevents insulin resistance after surgical trauma in female pigs

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WNT-Mediated Regulation of FOXO1 Constitutes a Critical Axis Maintaining Pubertal Mammary Stem Cell Homeostasis

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Functional Redundancy between β1 and β3 Integrin in Activating the IR/Akt/mTORC1 Signaling Axis to Promote ErbB2-Driven Breast Cancer

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Hepatic gluconeogenic response to single and long-term SGLT2 inhibition in lean/obese male hepatic G6pc-reporter mice

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A novel small molecule supports the survival of cultured dopamine neurons and may restore the dopaminergic innervation of the brain in the MPTP mouse model of Parkinson's disease

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3D Cellular Architecture Modulates Tyrosine Kinase Activity, Thereby Switching CD95-Mediated Apoptosis to Survival

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Impaired skeletal muscle mitochondrial pyruvate uptake rewires glucose metabolism to drive whole-body leanness

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Astrocyte truncated tropomyosin receptor kinase B mediates brain‐derived neurotrophic factor anti‐apoptotic effect leading to neuroprotection

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IGF-2 Preprograms Maturing Macrophages to Acquire Oxidative Phosphorylation-Dependent Anti-inflammatory Properties

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Auto-regulation of Secretory Flux by Sensing and Responding to the Folded Cargo Protein Load in the Endoplasmic Reticulum

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Reciprocal Effects of Fibroblast Growth Factor Receptor Signaling on Dengue Virus Replication and Virion Production

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Haem oxygenase‐1 up‐regulation by rosiglitazone via ROS‐dependent Nrf2‐antioxidant response elements axis or PPARγ attenuates LPS‐mediated lung inflammation

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Betulinic acid alleviates endoplasmic reticulum stress‐mediated nonalcoholic fatty liver disease through activation of farnesoid X receptors in mice

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Regulation of the Elongation Phase of Protein Synthesis Enhances Translation Accuracy and Modulates Lifespan

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Norepinephrine protects against apoptosis of mesenchymal stem cells induced by high glucose

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Methyltransferase Nsd2 Ensures Germinal Center Selection by Promoting Adhesive Interactions between B Cells and Follicular Dendritic Cells

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KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism

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The Release of Adipose Stromal Cells from Subcutaneous Adipose Tissue Regulates Ectopic Intramuscular Adipocyte Deposition

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Intrinsic High Aerobic Capacity in Male Rats Protects Against Diet-Induced Insulin Resistance

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Parvifoline AA Promotes Susceptibility of Hepatocarcinoma to Natural Killer Cell-Mediated Cytolysis by Targeting Peroxiredoxin

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Interaction of Discoidin Domain Receptor 1 with a 14-3-3-Beclin-1-Akt1 Complex Modulates Glioblastoma Therapy Sensitivity

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Protein Kinase C Epsilon Deletion in Adipose Tissue, but Not in Liver, Improves Glucose Tolerance

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Lipolysis Triggers a Systemic Insulin Response Essential for Efficient Energy Replenishment of Activated Brown Adipose Tissue in Mice

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Aberrant ERBB4-SRC Signaling as a Hallmark of Group 4 Medulloblastoma Revealed by Integrative Phosphoproteomic Profiling

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Paneth Cells Respond to Inflammation and Contribute to Tissue Regeneration by Acquiring Stem-like Features through SCF/c-Kit Signaling

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AhR ligand aminoflavone suppresses α6‐integrin–Src–Akt signaling to attenuate tamoxifen resistance in breast cancer cells

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BMP6 down-regulates GDNF expression through SMAD1/5 and ERK1/2 signaling pathways in human granulosa-lutein cells

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Knockout of USP19 Deubiquitinating Enzyme Prevents Muscle Wasting by Modulating Insulin and Glucocorticoid Signaling

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Loss of PRMT5 Promotes PDGFRα Degradation during Oligodendrocyte Differentiation and Myelination

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COMMD5/HCaRG Hooks Endosomes on Cytoskeleton and Coordinates EGFR Trafficking

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EGFR Ligands Differentially Stabilize Receptor Dimers to Specify Signaling Kinetics

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Acetyl-CoA Carboxylase 1-Dependent Protein Acetylation Controls Breast Cancer Metastasis and Recurrence

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Liver Cancer Initiation Requires p53 Inhibition by CD44-Enhanced Growth Factor Signaling

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Cross Talk between One-Carbon Metabolism, Eph Signaling, and Histone Methylation Promotes Neural Stem Cell Differentiation

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An ERK-Dependent Feedback Mechanism Prevents Hematopoietic Stem Cell Exhaustion

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Targeting p38α Increases DNA Damage, Chromosome Instability, and the Anti-tumoral Response to Taxanes in Breast Cancer Cells

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EF24 (a curcumin analog) and ZSTK474 emphasizes the effect of cabozantinib in medullary thyroid cancer

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(−)‐ Epigallocatechin‐3‐gallate induces GRP78 accumulation in the ER and shifts mesothelioma constitutive UPR into proapoptotic ER stress

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Systematic Functional Annotation of Somatic Mutations in Cancer

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Low-Protein Diet Induces IRE1α-Dependent Anticancer Immunosurveillance

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Metabolic Maturation during Muscle Stem Cell Differentiation Is Achieved by miR-1/133a-Mediated Inhibition of the Dlk1-Dio3 Mega Gene Cluster

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Angiogenin/Ribonuclease 5 Is an EGFR Ligand and a Serum Biomarker for Erlotinib Sensitivity in Pancreatic Cancer

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Clotrimazole is effective for the regression of endometriotic implants in a Wistar rat experimental model of endometriosis

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