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  1. Sep 2022
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    Inhibition of the CtBP complex and FBXO11 enhances MHC class II expression and anti-cancer immune responses
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    1. scibot 30 Sep 2022
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      DOI: 10.1016/j.ccell.2022.09.007

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    sciencedirect.com/science/article/pii/S1535610822004366
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    A nuclear cAMP microdomain suppresses tumor growth by Hippo pathway inactivation
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      DOI: 10.1016/j.celrep.2022.111412

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    sciencedirect.com/science/article/pii/S2211124722012530
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    Targeting the USP7/RRM2 axis drives senescence and sensitizes melanoma cells to HDAC/LSD1 inhibitors
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    sciencedirect.com/science/article/pii/S2211124722012335
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    Postnatal age-differential ASD-like transcriptomic, synaptic, and behavioral deficits in Myt1l-mutant mice
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    sciencedirect.com/science/article/pii/S2211124722012359
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    MCM7 supports the stemness of bladder cancer stem-like cells by enhancing autophagic flux
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    1. scibot 21 Sep 2022
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    ncbi.nlm.nih.gov/pmc/articles/PMC9468384/
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    CRISPR-Cas9 screen in human embryonic stem cells to identify genes required for neural differentiation
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    sciencedirect.com/science/article/pii/S2666166722005627
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    Control of ribosomal RNA synthesis by hematopoietic transcription factors
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    sciencedirect.com/science/article/pii/S1097276522008474
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    Cancer cell autophagy, reprogrammed macrophages, and remodeled vasculature in glioblastoma triggers tumor immunity
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    sciencedirect.com/science/article/pii/S1535610822003786
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    Posttranslational S-nitrosylation modification regulates HMGB1 secretion and promotes its proinflammatory and neurodegenerative effects
    1
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    sciencedirect.com/science/article/pii/S2211124722011585
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    Increased glucose metabolism in TAMs fuels O-GlcNAcylation of lysosomal Cathepsin B to promote cancer metastasis and chemoresistance
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    1. scibot 11 Sep 2022
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    sciencedirect.com/science/article/pii/S1535610822003762
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    Ablating Lgr5-expressing prostatic stromal cells activates the ERK-mediated mechanosensory signaling and disrupts prostate tissue homeostasis
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    sciencedirect.com/science/article/pii/S2211124722011378
  13. Aug 2022
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    Arid1a mutation suppresses TGF-β signaling and induces cholangiocarcinoma
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    1. scibot 31 Aug 2022
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    sciencedirect.com/science/article/pii/S2211124722010713
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    PH domain-mediated autoinhibition and oncogenic activation of Akt
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    1. scibot 31 Aug 2022
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      DOI: 10.7554/eLife.80148

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    ncbi.nlm.nih.gov/pmc/articles/PMC9417420/
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    Host and microbiome features of secondary infections in lethal covid-19
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    1. scibot 27 Aug 2022
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    sciencedirect.com/science/article/pii/S2589004222011981
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    Mitochondrial microproteins link metabolic cues to respiratory chain biogenesis
    1
    1. scibot 17 Aug 2022
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      DOI: 10.1016/j.celrep.2022.111204

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    sciencedirect.com/science/article/pii/S221112472201021X
  18. Jul 2022
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AKT1 mediates multiple phosphorylation events that functionally promote HSF1 activation
    1
    1. scibot 27 Jul 2022
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      DOI: 10.1111/febs.16375

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    ncbi.nlm.nih.gov/pmc/articles/PMC9309721/
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    Pathological mitophagy disrupts mitochondrial homeostasis in Leber’s hereditary optic neuropathy
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    1. scibot 27 Jul 2022
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    sciencedirect.com/science/article/pii/S2211124722009305
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    GCN2 inhibition sensitizes arginine-deprived hepatocellular carcinoma cells to senolytic treatment
    1
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      DOI: 10.1016/j.cmet.2022.06.010

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    sciencedirect.com/science/article/pii/S1550413122002303
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    Resolution of R-loops by topoisomerase III-β (TOP3B) in coordination with the DEAD-box helicase DDX5
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    sciencedirect.com/science/article/pii/S2211124722008658
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    A ROS-dependent mechanism promotes CDK2 phosphorylation to drive progression through S phase
    1
    1. scibot 12 Jul 2022
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    sciencedirect.com/science/article/pii/S1534580722004488
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    Context-dependent regulation of ferroptosis sensitivity
    1
    1. scibot 09 Jul 2022
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      DOI: 10.1016/j.chembiol.2022.06.004

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    sciencedirect.com/science/article/pii/S2451945622002367
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    Neoadjuvant chemotherapy induces genomic and transcriptomic changes in ovarian cancer
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    1. scibot 06 Jul 2022
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      DOI: 10.1158/0008-5472.CAN-21-1467

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    ncbi.nlm.nih.gov/pmc/articles/PMC8936832/
  26. Jun 2022
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    Neutrophil Extracellular Traps Mediate Acute Liver Failure in Regulation of miR-223/neutrophil Elastase Signaling in Mice
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    1. scibot 28 Jun 2022
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    sciencedirect.com/science/article/pii/S2352345X22000972
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    Coagulation factors promote brown adipose tissue dysfunction and abnormal systemic metabolism in obesity
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    sciencedirect.com/science/article/pii/S2589004222008197
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    Methionine oxidation activates pyruvate kinase M2 to promote pancreatic cancer metastasis
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    sciencedirect.com/science/article/pii/S109727652200541X
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    Actions of Parathyroid Hormone Ligand Analogs in Humanized PTH1R Knock-In Mice
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      DOI: 10.1210/endocr/bqac054

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    academic.oup.com/endo/article-abstract/163/7/bqac054/6573221
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    Progesterone limits the tumor-promoting effects of the beta-subunit of human chorionic gonadotropin via non-nuclear receptors
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    sciencedirect.com/science/article/pii/S2589004222007982
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    Supramolecular assembly of GSK3α as a cellular response to amino acid starvation
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    sciencedirect.com/science/article/pii/S1097276522004920
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    Protein interactome and cell-type expression analyses reveal that cytoplasmic FMR1-interacting protein 1 (CYFIP1), but not CYFIP2, associates with astrocytic focal adhesion
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      DOI: 10.1111/jnc.15622

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15622
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    Parsing the role of NSP1 in SARS-CoV-2 infection
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    ncbi.nlm.nih.gov/pmc/articles/PMC9133101/
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    Satellite cell-specific deletion of Cipc alleviates myopathy in mdx mice
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    sciencedirect.com/science/article/pii/S2211124722007215
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    IL18 signaling causes islet β cell development and insulin secretion via different receptors on acinar and β cells
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    sciencedirect.com/science/article/pii/S1534580722003707
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    LL-37 transports immunoreactive cGAMP to activate STING signaling and enhance interferon-mediated host antiviral immunity
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    sciencedirect.com/science/article/pii/S2211124722006556
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    YAP1 activation is associated with the progression and response to immunotherapy of non-muscle invasive bladder cancer
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      DOI: 10.1016/j.ebiom.2022.104092

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    sciencedirect.com/science/article/pii/S2352396422002730
  39. May 2022
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    The epilepsy-associated protein PCDH19 undergoes NMDA receptor-dependent proteolytic cleavage and regulates the expression of immediate-early genes
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      DOI: 10.1016/j.celrep.2022.110857

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    sciencedirect.com/science/article/pii/S2211124722006301
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    Stromal cell senescence contributes to impaired endometrial decidualization and defective interaction with trophoblast cells
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      DOI: 10.1093/humrep/deac112

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    academic.oup.com/humrep/advance-article/doi/10.1093/humrep/deac112/6590738
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    Harnessing cortical plasticity via gabapentinoid administration promotes recovery after stroke
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      DOI: 10.1093/brain/awac103

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    academic.oup.com/brain/advance-article/doi/10.1093/brain/awac103/6589844
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Durable immunogenicity, adaptation to emerging variants and low dose efficacy of AAV-based COVID19 platform in macaques
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      DOI: 10.1016/j.ymthe.2022.05.007

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    ncbi.nlm.nih.gov/pmc/articles/PMC9088091/
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    C/EBPδ-induced epigenetic changes control the dynamic gene transcription of S100a8 and S100a9
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      DOI: 10.7554/eLife.75594

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    ncbi.nlm.nih.gov/pmc/articles/PMC9122501/
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    Low concentrations of bisphenol A promote the activation of the mitochondrial apoptotic pathway on Beta-TC-6 cells via the generation of intracellular reactive oxygen species and mitochondrial superoxide
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      DOI: 10.1002/jbt.23099

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    Mitotic Spindle Positioning (MISP) is an actin bundler that selectively stabilizes the rootlets of epithelial microvilli
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    Histone deacetylase 3 contributes to the antiviral innate immunity of macrophages by interacting with FOXK1 to regulate STAT1/2 transcription
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    Roflupram attenuates α-synuclein-induced cytotoxicity and promotes the mitochondrial translocation of Parkin in SH-SY5Y cells overexpressing A53T mutant α-synuclein
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    Gestational Diabetes Epigenetically Reprograms the Cart Promoter in Fetal Ovary, Causing Subfertility in Adult Life
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    Inhibition of PHLPP1/2 phosphatases rescues pancreatic β-cells in diabetes
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    Modulation of LIN28B/Let-7 Signaling by Propranolol Contributes to Infantile Hemangioma Involution | Arteriosclerosis, Thrombosis, and Vascular Biology
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    TRIM8 modulates the EWS/FLI oncoprotein to promote survival in Ewing sarcoma
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    Silenced ZNF154 Is Associated with Longer Survival in Resectable Pancreatic Cancer
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  191. www.nature.com www.nature.com
    Reversal of peripheral nerve injury-induced neuropathic pain and cognitive dysfunction via genetic and tomivosertib targeting of MNK
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    Treatment of type 2 diabetes with the designer cytokine IC7Fc
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      GAPDH

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  193. elifesciences.org elifesciences.org
    Caspase-mediated cleavage of IRE1 controls apoptotic cell commitment during endoplasmic reticulum stress
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    Widespread Selection for Oncogenic Mutant Allele Imbalance in Cancer
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    Microbially Produced Imidazole Propionate Impairs Insulin Signaling through mTORC1
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    The Oncogenic Action of NRF2 Depends on De-glycation by Fructosamine-3-Kinase
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    Translational regulation of protrusion-localized RNAs involves silencing and clustering after transport
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      anti-GAPDH

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  199. biosignaling.biomedcentral.com biosignaling.biomedcentral.com
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    Proline-arginine poly-dipeptide encoded by the C9orf72 repeat expansion inhibits adenosine deaminase acting on RNA
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    Heparan Sulfate Proteoglycan Sulfation Regulates Uterine Differentiation and Signaling During Embryo Implantation
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    Human Breast Cancer Xenograft Model Implicates Peroxisome Proliferator–activated Receptor Signaling as Driver of Cancer-induced Muscle Fatigue
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    Effects of Prolonged Dietary Curcumin Exposure on Skeletal Muscle Biochemical and Functional Responses of Aged Male Rats
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    BE-FLARE: a fluorescent reporter of base editing activity reveals editing characteristics of APOBEC3A and APOBEC3B
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    Activation of Group II Metabotropic Glutamate Receptors Promotes LTP Induction at Schaffer Collateral-CA1 Pyramidal Cell Synapses by Priming NMDA Receptors
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      AB_561053

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  209. onlinelibrary.wiley.com onlinelibrary.wiley.com
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      RRID:AB_10698756

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  210. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Fibroblast growth factor 2 regulates activity and gene expression of human post‐mitotic excitatory neurons
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  211. onlinelibrary.wiley.com onlinelibrary.wiley.com
    BMP Signaling Mediated by BMPR1A in Osteoclasts Negatively Regulates Osteoblast Mineralization Through Suppression of Cx43
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      AB_1031003

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  212. www.sciencedirect.com www.sciencedirect.com
    Neuronal VCP loss of function recapitulates FTLD-TDP pathology
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      2118

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  213. www.sciencedirect.com www.sciencedirect.com
    Sustained treatment with an α5 GABA A receptor negative allosteric modulator delays excitatory circuit development while maintaining GABAergic neurotransmission
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      2118

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