1,029 Matching Annotations
  1. Apr 2024
  2. www.embopress.org www.embopress.org
    The regulatory relationship between NAMPT and PD-L1 in cancer and identification of a dual-targeting inhibitor
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    embopress.org/doi/full/10.1038/s44321-024-00051-z
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metabolic priming by multiple enzyme systems supports glycolysis, HIF1α stabilisation, and human cancer cell survival in early hypoxia
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    ncbi.nlm.nih.gov/pmc/articles/PMC11021510/
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Context-dependent roles for ubiquitous mitochondrial creatine kinase CKMT1 in breast cancer progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC11100297/
  5. www.sciencedirect.com www.sciencedirect.com
    A p85 isoform switch enhances PI3K activation on endosomes by a MAP4- and PI3P-dependent mechanism
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    sciencedirect.com/science/article/pii/S2211124724004479
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    Transcriptomics studies reveal functions of Transglutaminase 2 in breast cancer cells using membrane permeable and impermeable inhibitors
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    sciencedirect.com/science/article/pii/S0022283624001645
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-cell Transcriptome Analysis Identifies Senescent Osteocytes as Contributors to Bone Destruction in Breast Cancer Metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10980159/
  8. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16364
  9. link.springer.com link.springer.com
    NCS-1 protein regulates TRPA1 channel through the PI3K pathway in breast cancer and neuronal cells
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    link.springer.com/article/10.1007/s13105-024-01016-z
  10. link.springer.com link.springer.com
    Functionalized siRNA-chitosan nanoformulations promote triple-negative breast cancer cell death via blocking the miRNA-21/AKT/ERK signaling axis: in-silico and in vitro studies
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    link.springer.com/article/10.1007/s00210-024-03068-w
  11. www.sciencedirect.com www.sciencedirect.com
    Pharmacological induction of chromatin remodeling drives chemosensitization in triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2666379124001733
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    Genetic interactions reveal distinct biological and therapeutic implications in breast cancer
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    sciencedirect.com/science/article/pii/S1535610824000916
  13. pubs.rsc.org pubs.rsc.org
    Effectiveness of a novel gene nanotherapy based on putrescine for cancer treatment
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    pubs.rsc.org/en/content/articlelanding/2023/bm/d2bm01456d
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Non-Viral DNA Delivery System Consisting of Multifunctional Chimaeric Peptide Fused with Zinc Finger Protein
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    ncbi.nlm.nih.gov/pmc/articles/PMC10981093/
  15. www.sciencedirect.com www.sciencedirect.com
    Multifunctional host-defense peptides isolated from skin secretions of the banana tree dwelling frog Boana platanera (Hylidae; Hylinae)
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    sciencedirect.com/science/article/pii/S0300908424000701
  16. Mar 2024
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MARCH2, a novel oncogene-regulated SNAIL E3 ligase, suppresses triple negative breast cancer metastases
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    ncbi.nlm.nih.gov/pmc/articles/PMC10977041/
  18. www.futuremedicine.com www.futuremedicine.com
    Alteration of DNA methyltransferases by eribulin elicits broad DNA methylation changes with potential therapeutic implications for triple-negative breast cancer
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    futuremedicine.com/doi/10.2217/epi-2023-0339
  19. www.sciencedirect.com www.sciencedirect.com
    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
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    sciencedirect.com/science/article/pii/S2451945624000874
  20. www.sciencedirect.com www.sciencedirect.com
    IQGAP1 and NWASP promote human cancer cell dissemination and metastasis by regulating β1-integrin via FAK and MRTF/SRF
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    sciencedirect.com/science/article/pii/S2211124724003176
  21. www.sciencedirect.com www.sciencedirect.com
    Multiparatopic antibodies induce targeted downregulation of programmed death-ligand 1
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    sciencedirect.com/science/article/pii/S2451945624000886
  22. www.nature.com www.nature.com
    Light-mediated intracellular polymerization
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    nature.com/articles/s41596-024-00970-8
  23. www.sciencedirect.com www.sciencedirect.com
    Hypoxia-inducible factor 1 recruits FACT and RNF20/40 to mediate histone ubiquitination and transcriptional activation of target genes
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    sciencedirect.com/science/article/pii/S2211124724003000
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    MTCH2 stimulates cellular proliferation and cycles via PI3K/Akt pathway in breast cancer
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    sciencedirect.com/science/article/pii/S2405844024042038
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    De novo steroidogenesis in tumor cells drives bone metastasis and osteoclastogenesis
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    sciencedirect.com/science/article/pii/S221112472400264X
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification and characterization of a small molecule Bcl-2 Functional Converter
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    ncbi.nlm.nih.gov/pmc/articles/PMC10911799/
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Role of hydroxymethylglutharyl-coenzyme A reductase in the induction of stem-like states in breast cancer
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10902018/
  28. www.biorxiv.org www.biorxiv.org
    The transcription factor RIP140 regulates interferon γ signaling in breast cancer
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    biorxiv.org/content/10.1101/2024.02.15.580503v1
  29. Feb 2024
  30. www.sciencedirect.com www.sciencedirect.com
    YAP mediates apoptosis through failed integrin adhesion reinforcement
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    sciencedirect.com/science/article/pii/S2211124724001396
  31. 52.53.155.43 52.53.155.43
    Volumetric Compression Shifts Rho GTPase Balance and Induces Mechanobiological Cell State Transition
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    52.53.155.43/f16191d77bff2fc87d72f7e8ed270d7e66f8124e/2023.10.08.561452v1.full-html.html
  32. aacrjournals.org aacrjournals.org
    Osteoclast-Cancer Cell Metabolic Crosstalk Confers PARP Inhibitor Resistance in Bone Metastatic Breast Cancer
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    aacrjournals.org/cancerres/article/84/3/449/733850/Osteoclast-Cancer-Cell-Metabolic-Cross-talk
  33. 52.53.155.43 52.53.155.43
    can-23-0902-html.html
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  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrative modelling and analysis of signalling crosstalk reveal molecular switches coordinating YAP transcriptional activities
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    ncbi.nlm.nih.gov/pmc/articles/PMC10877689/
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PLK4 as a potential target to enhance radiosensitivity in triple-negative breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10873955/
  36. www.sciencedirect.com www.sciencedirect.com
    In vivo CRISPR knockout screen identifies p47 as a suppressor of HER2+ breast cancer metastasis by regulating NEMO trafficking and autophagy flux
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    sciencedirect.com/science/article/pii/S2211124724001086
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Association of changes in expression of HDAC and SIRT genes after drug treatment with cancer cell line sensitivity to kinase inhibitors
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    ncbi.nlm.nih.gov/pmc/articles/PMC10878021/
  38. 52.53.155.43 52.53.155.43
    An improved PDE6D inhibitor combines with Sildenafil to synergistically inhibit KRAS mutant cancer cell growth
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    52.53.155.43/d64025fcba7405c73976a9e0dc65e9989e0d835f/2023.08.23.554263v1.full-html.html
  39. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17097
  40. www.sciencedirect.com www.sciencedirect.com
    Increased matrix stiffness enhances pro-tumorigenic traits in a physiologically relevant breast tissue- monocyte 3D model
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    sciencedirect.com/science/article/pii/S1742706124000898
  41. www.sciencedirect.com www.sciencedirect.com
    Cullin-RING ligases employ geometrically optimized catalytic partners for substrate targeting
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    sciencedirect.com/science/article/pii/S1097276524000893
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AEP-cleaved DDX3X induces alternative RNA splicing events to mediate cancer cell adaptation in harsh microenvironments
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    ncbi.nlm.nih.gov/pmc/articles/PMC10849765/
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protein Kinase D drives the secretion of invasion mediators in triple-negative breast cancer cell lines
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    ncbi.nlm.nih.gov/pmc/articles/PMC10844833/
  44. onlinelibrary.wiley.com onlinelibrary.wiley.com
    SAA1-dependent reprogramming of adipocytes by tumor cells is associated with triple negative breast cancer aggressiveness
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    onlinelibrary.wiley.com/doi/full/10.1002/ijc.34859
  45. link.springer.com link.springer.com
    Functionalized tetrahedral DNA frameworks for the capture of circulating tumor cells
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    link.springer.com/article/10.1038/s41596-023-00943-3
  46. www.sciencedirect.com www.sciencedirect.com
    Targeting TOP2B as a vulnerability in aging and aging-related diseases
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    sciencedirect.com/science/article/pii/S0925443924000292
  47. www.biorxiv.org www.biorxiv.org
    Sulfatase 2 Inhibition Sensitizes Triple-Negative Breast Cancer Cells to Chemotherapy Through Augmentation of Extracellular ATP
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    biorxiv.org/content/10.1101/2023.09.15.557965v1
  48. www.sciencedirect.com www.sciencedirect.com
    Targeting EMSY-mediated methionine metabolism is a potential therapeutic strategy for triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2666379124000053
  49. www.sciencedirect.com www.sciencedirect.com
    SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion
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    sciencedirect.com/science/article/pii/S0092867424000102
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An estrogen-regulated long non-coding RNA NCALD promotes luminal breast cancer proliferation by activating GRHL2
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    ncbi.nlm.nih.gov/pmc/articles/PMC10829383/
  51. Jan 2024
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10187264/
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Liver X receptors induce antiproliferative effects in basal‐like breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10552888/
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MCAK Inhibitors Induce Aneuploidy in Triple-Negative Breast Cancer Models
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    ncbi.nlm.nih.gov/pmc/articles/PMC10340532/
  55. www.sciencedirect.com www.sciencedirect.com
    Exploring the Multifaceted Impact of Lanthanides on Physiological Pathways in Human Breast Cancer Cells
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    sciencedirect.com/science/article/pii/S0300483X2400012X
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HSF1 inhibits antitumor immune activity in breast cancer by suppressing CCL5 to block CD8+ T cell recruitment.
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    ncbi.nlm.nih.gov/pmc/articles/PMC10790131/
  57. www.sciencedirect.com www.sciencedirect.com
    A novel antagonist of the CCL5/CCR5 axis suppresses the tumor growth and metastasis of triple-negative breast cancer by CCR5-YAP1 regulation
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    sciencedirect.com/science/article/pii/S0304383524000296
  58. www.sciencedirect.com www.sciencedirect.com
    Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma
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    sciencedirect.com/science/article/pii/S1097276523010225
  59. www.sciencedirect.com www.sciencedirect.com
    PAPAS promotes differentiation of mammary epithelial cells and suppresses breast carcinogenesis
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    sciencedirect.com/science/article/pii/S2211124723016558
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-essential amino acid availability influences proteostasis and breast cancer cell survival during proteotoxic stress
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    ncbi.nlm.nih.gov/pmc/articles/PMC10330057/
  61. www.sciencedirect.com www.sciencedirect.com
    Metabolic switch regulates lineage plasticity and induces synthetic lethality in triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S1550413123004552
  62. Dec 2023
  63. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13568
  64. onlinelibrary.wiley.com onlinelibrary.wiley.com
    First evidence of AXL expression on circulating tumor cells in metastatic breast cancer patients: A proof-of-concept study
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    onlinelibrary.wiley.com/doi/10.1002/cam4.6843
  65. www.sciencedirect.com www.sciencedirect.com
    Metabolic regulation of homologous recombination repair by MRE11 lactylation
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    sciencedirect.com/science/article/pii/S009286742301276X
  66. www.sciencedirect.com www.sciencedirect.com
    G-quadruplex is critical to epigenetic activation of the lncRNA HOTAIR in cancer cells
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    sciencedirect.com/science/article/pii/S2589004223026366
  67. www.sciencedirect.com www.sciencedirect.com
    Epinephrine inhibits PI3Kα via the Hippo kinases
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    sciencedirect.com/science/article/pii/S2211124723015474
  68. www.sciencedirect.com www.sciencedirect.com
    Choroid plexus mast cells drive tumor-associated hydrocephalus
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    sciencedirect.com/science/article/pii/S0092867423011820
  69. www.sciencedirect.com www.sciencedirect.com
    Heterogeneity and transcriptional drivers of triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2211124723015760
  70. link.springer.com link.springer.com
    Transcriptome reprogramming through alternative splicing triggered by apigenin drives cell death in triple-negative breast cancer
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    link.springer.com/article/10.1038/s41419-023-06342-6
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Cell Surface-Binding Antibody Atlas Nominates a MUC18-Directed Antibody–Drug Conjugate for Targeting Melanoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10646479/
  72. www.nature.com www.nature.com
    Discovery of a Drug-like, Natural Product-Inspired DCAF11 Ligand Chemotype
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    nature.com/articles/s41467-023-43657-6
  73. www.nature.com www.nature.com
    TNFRSF19 promotes endoplasmic reticulum stress-induced paraptosis via the activation of the MAPK pathway in triple-negative breast cancer cells
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    nature.com/articles/s41417-023-00696-x
  74. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1873-3468.14774
  75. www.biorxiv.org www.biorxiv.org
    A novel antagonist of the CCL5/CCR5 axis suppresses the tumor growth and metastasis of triple-negative breast cancer by CCR5-YAP1 regulation
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    biorxiv.org/content/10.1101/2023.11.15.567291v1
  76. 52.53.155.43 52.53.155.43
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  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Key regulator PNPLA8 drives phospholipid reprogramming induced proliferation and migration in triple-negative breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10683240/
  78. Nov 2023
  79. www.sciencedirect.com www.sciencedirect.com
    Super-resolution microscopy reveals the nanoscale cluster architecture of the DEK protein cancer biomarker
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    sciencedirect.com/science/article/pii/S2589004223023544
  80. www.sciencedirect.com www.sciencedirect.com
    Enniatin A inhibits the chaperone Hsp90 and unleashes the immune system against triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2589004223023854
  81. 52.53.155.43 52.53.155.43
    LncFASA promotes cancer ferroptosis via modulating PRDX1 phase separation
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  82. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Tumor cell SPTBN1 inhibits M2 polarization of macrophages by suppressing CXCL1 expression
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    onlinelibrary.wiley.com/doi/10.1002/jcp.31146
  83. www.sciencedirect.com www.sciencedirect.com
    Anti-tumor effect of PD-L1-targeting antagonistic aptamer-ASO delivery system with dual inhibitory function in immunotherapy
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    sciencedirect.com/science/article/pii/S2451945623003719
  84. www.nature.com www.nature.com
    In situ label-free X-ray imaging for visualizing the localization of nanomedicines and subcellular architecture in intact single cells
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    nature.com/articles/s41596-023-00902-y
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Serine protease inhibitors decrease metastasis in prostate, breast, and ovarian cancers
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    ncbi.nlm.nih.gov/pmc/articles/PMC10620120/
  86. 52.53.155.43 52.53.155.43
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    Widespread BRCA1/2-independent homologous recombination defects are caused by alterations in RNA-binding proteins
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    sciencedirect.com/science/article/pii/S2666379123004329
  88. www.sciencedirect.com www.sciencedirect.com
    PD-L1-mediated immune evasion in triple-negative breast cancer is linked to the loss of ZNF652
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    sciencedirect.com/science/article/pii/S2211124723013554
  89. www.sciencedirect.com www.sciencedirect.com
    Insulin receptor loss impairs mammary tumorigenesis in mice
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    sciencedirect.com/science/article/pii/S2211124723012639
  90. Oct 2023
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mechanistic Insights into the Anti-Proliferative Action of Gut Microbial Metabolites against Breast Adenocarcinoma Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10606851/
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    N-terminal acetylation shields proteins from degradation and promotes age-dependent motility and longevity
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    ncbi.nlm.nih.gov/pmc/articles/PMC10611716/
  93. www.sciencedirect.com www.sciencedirect.com
    Differential DNA damage repair and PARP inhibitor vulnerability of the mammary epithelial lineages
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