5,430 Matching Annotations
  1. Jan 2026
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    The co-delivery of Programmed Death 1 ligands enhances and prolongs rAAV-mediated gene expression in pre-immunized mice
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    nature.com/articles/s41434-025-00588-9
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    PRMT5 upregulates KCNMB4 expression via histone methylation to promote paclitaxel resistance in advanced nasopharyngeal carcinoma
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    nature.com/articles/s41419-025-08190-y
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    Protocols to evaluate mutant specificity of an oncogene-targeting siRNA using orthogonal in vitro and in vivo approaches
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    sciencedirect.com/science/article/pii/S2666166725007294
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    Deubiquitinase USP45 stabilizes RTCB and DDX1, promoting tumorigenesis and chemoresistance
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    sciencedirect.com/science/article/pii/S0141813025105278
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    Migrasome-driven mitocytosis relieves mitochondrial damage induced by chikungunya virus TF and 6K
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    sciencedirect.com/science/article/pii/S2949928325001178
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    Dual-faced PUMA in CRC: A cytoplasmic autophagy repressor and mitochondrial mitophagy promoter
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    Membrane-protein-mediated phase separation orchestrates organelle contact sites
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    Guaianolide dimer KGA-1002 targets GRP94 and triggers unfolded protein response-associated degradation of SKP2/AKT axis as a novel antihepatoma agent
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    sciencedirect.com/science/article/pii/S209012322600010X
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    Endometrial stromal cell-derived TMAO sustains decidualization to prevent recurrent spontaneous abortion
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    UBE2O-mediated monoubiquitination licenses NLRP6 inflammasome activation in the intestine
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    Scaffolding-dependent CASP1 constrains excessive cell-intrinsic inflammatory signaling in leukemia
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    KRASG12/13 mutation modulates CRC outcomes via disrupting positive feedback between macrophage and CD4+ T cell
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    DNA-PKcs controls the cytotoxic T cell response to cancer and transplant allograft through regulating LAT-dependent signaling
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    B cells disrupt tertiary lymphoid structure formation and suppress anti-tumor immunity
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    Candida albicans drives colorectal cancer progression by inducing hypoxia signaling
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    Calcium and Cadmium Activate ESRRB to Mediate Cell Stemness and Pluripotency
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    BRD2 bridges TFIID and MOF-H4K16ac-containing nucleosomes to promote transcriptional initiation
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    A CLOCK-targeting lncRNA induces trained immunity against tuberculosis
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    Affinity maturation and light-chain-mediated paratope diversification anticipates viral evolution
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    Crosstalk between the ribosome quality control-associated E3 ubiquitin ligases LTN1 and RNF10
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1873-3468.70230
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    Parallel ZNF598 and GIGYF2 pathways mediate conserved collision-dependent mRNA decay with distinct endonucleolytic features
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    Synergistic intragenic epigenetic deregulation by IDH2 and SRSF2 mutations causes mis-splicing of key transcriptional regulators
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    Pathogenic Gαo Mutants Drive Dominant GPCR Coupling in GNAO1 Encephalopathies
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    LncRNA DANCR Activates p38/mTOR‐Mediated Autophagy via ANXA2 to Exacerbate Oxygen‐Induced Retinal Neovascularization in Mice
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    Slippery Liquid-Infused Porous Surfaces Using Eucalyptus Oil-Loaded Bead-on-String Nanofibers for Antibacterial, Antifungal, and Antibiofilm Applications
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    ANP32A-mediated Histone 3 K27 Acetylation is Essential for Sotorasib Activity in KRAS-mutant Non-Small Cell Lung Cancer
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    Identification of aryl hydrocarbon receptor as a functional target that enhances astrocytic ApoE secretion
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    Structural and functional characterization of the antigenicity of influenza A virus hemagglutinin subtype H15
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    AARS1-mediated AKR1B10 lactylation stabilizes an aerobic glycolysis-positive feedback loop to drive lenvatinib resistance in hepatocellular carcinoma
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    5-HT reuptake blockade induces pyroptosis in BRAFV600E-mutated melanomas via remodeling histone serotonylation
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  35. Dec 2025
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    A TRIM21–UCHL3–ITCH–SIPA1 axis promotes colorectal cancer growth and metastasis
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    Paralogs of Slitrk cell adhesion molecules configure excitatory synapse specificity via distinct cellular mechanisms
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    Deprivation of EGFR signal causes senolysis in PDAC with CDK4/6 inhibition
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    Mitochondrial glutamine import sustains electron transport chain integrity independently of glutaminolysis in cancer
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    Mast cell-specific CysLT2 receptor signaling inhibits cysteinyl leukotriene-dependent mast cell activation and type 2 allergic lung inflammation
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    Repeat-associated non-AUG translation as a common mechanism for the polyGln ataxias
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    Structure-Based Development of Ultra-Broad-Spectrum 3C-Like Protease Inhibitors
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202512342
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    Retroviral insertions contributed to the divergence of human and chimpanzee brains
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    Mechanism of cotranslational modification of histones H2A and H4 by MetAP1 and NatD
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    pmc.ncbi.nlm.nih.gov/articles/PMC12716425/
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    Mechanism of cotranslational modification of histones H2A and H4 by MetAP1 and NatD
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    Anti-FAP CAR-NK cells as a novel targeted therapy against cervical cancer and cancer-associated fibroblasts
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    Downregulation of ZBTB7A/LRF increases fetal hemoglobin expression in β0-thalassemia/hemoglobin E erythroid cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12715185/
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    KRT81 promotes metastasis of colorectal cancer by acting as a protein scaffold for ezrin
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    BET inhibitor-based combinations targeting novel dependencies in MECOM-rearranged (r) AML
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    Core passive and facultative mTOR-mediated mechanisms coordinate mammalian protein synthesis and decay
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    ZAP inhibits double-stranded RNA virus infection by degrading negative-strand RNA and blocking the elongation phase of viral protein synthesis
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    An engineered nanosystem for reprogramming circulating malignant cells and the tumor-immune axis
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    F13A1-Mediated Macrophage Activation Promotes MASH Progression via the PKM2/HIF1A Pathway
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    Mutual Exclusion Analysis Shows that DUSP9 Negatively Regulates PD-L1 Expression and Acts as a Target to Enhance Anti-PD-1 Efficacy
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    General trends in the calnexin-dependent expression and pharmacological rescue of clinical CFTR variants
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    TFE3 fusion proteins promoted the progression of Xp11.2 translocation renal cell carcinoma through post-translational modification of PDL1 by upregulating CCND1/Cyclin D1
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    Intranasal Mosaic H1N1 Live Attenuated Influenza Vaccine Elicits Broad Cross‐Reactive Immunity and Protection Against Group 1 and 2 Influenza A Viruses
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    Serotonin-licensed macrophages potentiate chemoresistance via inositol metabolic crosstalk in ovarian cancer
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    Targeting CTGF overcomes resistance to CSF1R inhibitors by preventing CAF activation in colorectal cancer
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    Liprin-α1 enhances PHLDB3 oncogenic function in colorectal cancer via activation of mTORC2-AKT1 pathway
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    A 20-amino-acid Cardiovirus protein exhibits cytokine-mimicry activity to regulate viral replication
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    Targeting TFAP2β condensation suppresses the development of esophageal squamous cell carcinoma
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    A cell-state axis underlying colonization in carcinomas with implications for metastasis risk prediction and interception
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    Immune and viral surveillance of HIV-1C reservoirs in an Indian cohort
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    ARAP2 regulates responses to interferon-gamma by restricting SOCS1
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    piR-43452 suppresses bladder cancer progression and enhances gemcitabine sensitivity via GTSF1/PIWIL4-mediated LRP1 mRNA destabilization
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    Bile acids regulate lipid metabolism through selective actions on fatty acid absorption
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    Molecular mechanism of resistance to lonafarnib conferred by mutations in the cysteine-rich region of respiratory syncytial virus fusion glycoprotein and discovery of a lonafarnib-derived antiviral PROTAC
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    journals.asm.org/doi/10.1128/jvi.01487-25
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    The CEMIP Hyaluronidase is Elevated in Oligodendrocyte Progenitor Cells and Inhibits Oligodendrocyte Maturation
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